Hair care composition, application and hair cosmetic

Abstract

The invention belongs to the field of new daily chemical materials, and discloses a hair care composition which is characterized in that the composition is an oil-in-water emulsion system; micelles in the oil-in-water emulsification system are coated with an oil-soluble hair care conditioner; the oil-in-water emulsification system also comprises glycerol, hydrolyzed sericin and hydrolyzed silk fibroin; the weight ratio of the glycerol to the hydrolyzed sericin to the hydrolyzed silk fibroin is 5: (0.004-0.02): (0.002-0.01). According to the composition, the residence time of the oil-soluble hair care conditioner is prolonged, and the conditioning effect is improved; meanwhile, the invention further provides application and cosmetics of the composition.

Description

Technical Field

[0001] The invention relates to the field of new daily chemical materials, in particular to a hair care composition, use and hair cosmetics. Background Art

[0002] The applicant's R&D partner, Southwest University, has applied for an invention patent CN106947268B, which discloses a method for preparing a sericin / glycerol blended film, its products and applications. It demonstrates that the film has an antibacterial effect, can form a film in contact with the skin, and can block the invasion and growth of external pathogens.

[0003] This project is based on this solution and further expands the application of this product in the field of hair use.

[0004] In the process of hair conditioning, the most common problem is that, especially in transparent shampoo formulas, it is difficult for high-content oil-soluble conditioning agents to exist stably in the formula system and to keep in contact with the hair continuously to fully exert the hair conditioning effect.

[0005] The technical problem to be solved by this scheme is: how to further improve the hair care and conditioning ability of products containing oil-soluble hair conditioning ingredients. Summary of the invention

[0006] The object of the present invention is to provide a hair care composition which increases the residence time of an oil-soluble hair care conditioner and improves the conditioning effect;

[0007] Meanwhile, the invention also provides the use and cosmetics of the composition.

[0008] To achieve the above object, the present invention provides the following technical solutions:

[0009] A hair care composition, the composition being an oil-in-water emulsified system;

[0010] The micelles in the oil-in-water emulsion system are coated with an oil-soluble hair conditioning agent;

[0011] The oil-in-water emulsification system also includes glycerin, hydrolyzed sericin, and hydrolyzed silk fibroin;

[0012] The weight ratio of the glycerol, hydrolyzed sericin and hydrolyzed silk fibroin is 5:0.004-0.02:0.002-0.01.

[0013] In the present invention, micelles are used to wrap the oil-soluble hair conditioner, and glycerol and hydrolyzed sericin are used to form a flexible film. In addition, the hydrophilic and lipophilic properties of the hydrolyzed silk fibroin are used. On the one hand, it participates in the formation of micelles. On the other hand, when the micelles are demulsified, the hydrophilic end can be combined with the flexible film, and the lipophilic end can contact the oil-soluble hair conditioner, which can promote the oil-soluble hair conditioner to be evenly distributed between the flexible film and the hair, prevent the oil-soluble hair conditioner from being washed away by water, increase the residence time of the oil-soluble hair conditioner, and improve the conditioning effect.

[0014] At the same time, the present invention cleverly utilizes the cationic properties of hydrolyzed sericin and hydrolyzed silk fibroin, which can quickly come into contact with the hair when demulsifying, and have excellent hair surface adsorption and uniform film-forming properties.

[0015] Through the above combination of characteristics, the combination of the present invention has a better hair conditioning effect compared with other hair care products.

[0016] The action process of the above composition and hair can be roughly divided into the following steps:

[0017] Step 1: The composition or shampoo / conditioner containing the composition acts on the hair, and the hydrolyzed sericin is adsorbed on the hair. The hydrolyzed sericin and glycerin are mainly responsible for forming a flexible film;

[0018] Step 2: Rinse the hair with water. The micelles remaining on the hair are diluted and demulsified. The hydrolyzed silk fibroin and the oil-soluble hair conditioner are released. Since the hydrolyzed silk fibroin has strong cationicity and certain hydrophobicity, it will enter the flexible membrane with the oil-soluble hair conditioner and further penetrate into the space between the flexible membrane and the hair.

[0019] In this process, the hydrolyzed silk fibroin will be evenly distributed in the inner layer of the flexible membrane, its hydrophilic end will be connected to the flexible membrane, and its lipophilic end will be in contact with the oil-soluble hair conditioning agent, thereby improving the uniformity of the oil-soluble hair conditioning agent distributed on the hair surface;

[0020] After the hair is rinsed, the flexible film formed on its surface will protect the oil-soluble hair conditioning agent in the inner layer, so that the oil-soluble hair conditioning agent stays on the surface of the hair and works for a long time.

[0021] It should be noted that the amount of glycerol used in the present invention far exceeds the amount of hydrolyzed sericin, while the amount of glycerol used in CN106947268B is less than that of sericin. The reason is that in CN106947268B, the film is formed by pouring, so the amount of glycerol cannot be controlled too high, otherwise the glycerol will significantly dilute the sericin, making it impossible for the sericin to form a film. In the present application, the cationic properties of hydrolyzed sericin and the principle of hair adsorption are utilized. The hydrolyzed sericin will quickly adsorb to the hair. If the glycerol concentration in the emulsion is too low, the amount of glycerol involved in the film-forming process will be small. After repeated experiments, we determined that the amount of glycerol should be about 5wt% of the solution, and the more appropriate range is 3-7wt%;

[0022] In the above-mentioned hair care composition, the oil-soluble hair care conditioning agent is one or more combinations of squalane, vegetable oil, organic silicone, hydrogenated polyisobutene, hydrogenated polydecene, dioctyl carbonate, isododecane, isohexadecane hydrogenated rosin acid methyl ester, trimethylolpropane tricaprylate / tricaprate.

[0023] The vegetable oil is one or more combinations of jojoba seed oil, meadowfoam seed oil, macadamia nut oil, shea butter, coconut oil, and argan oil;

[0024] The organosiloxane is one or more combinations of polydimethylsiloxane, polydimethylsiloxane alcohol, amino-terminated polydimethylsiloxane, and phenyl polydimethylsiloxane.

[0025] In the above-mentioned hair care composition, the amount of the emulsifier in the water-in-oil emulsion system is 10-20 wt%.

[0026] In the above-mentioned hair care composition, the emulsifier is one or more combinations of polyglyceryl-2 isostearate, PEG-7 glyceryl cocoate, and PEG-30 hydrogenated castor oil.

[0027] In the above-mentioned hair care composition, the amount of the oil-soluble hair conditioning agent in the water-in-oil emulsion system is 30 to 50 wt %;

[0028] And / or, the concentration of glycerol in the oil-in-water emulsion system is 3-7 wt %.

[0029] At the same time, the present invention also discloses the use of any of the above hair care compositions in preparing hair cosmetics.

[0030] In the above-mentioned use, the cosmetic is shampoo or conditioner.

[0031] Finally, the present invention also discloses a hair cosmetic comprising any one of the above hair care compositions.

[0032] In the above-mentioned hair cosmetic, the amount of the hair care composition is 0.1 to 5 wt%.

[0033] Compared with the prior art, the present invention has the following beneficial effects:

[0034] In the present invention, micelles are used to encapsulate the oil-soluble hair conditioner, and glycerol and hydrolyzed sericin are used to form a flexible film. In addition, the surfactant and lipophilic properties of the hydrolyzed silk fibroin may participate in the formation of micelles. On the other hand, when the micelles are demulsified, the hydrophilic end thereof can be combined with the flexible film, and the lipophilic end can contact the oil-soluble hair conditioner, which can promote the oil-soluble hair conditioner to be evenly distributed between the flexible film and the hair, thereby preventing the oil-soluble hair conditioner from being washed away by water, increasing the residence time of the oil-soluble hair conditioner, and improving the conditioning effect.

[0035] At the same time, the present invention cleverly utilizes the cationic properties of hydrolyzed sericin and hydrolyzed silk fibroin, which can quickly come into contact with the hair when demulsifying and have excellent uniform film-forming properties on the hair surface.

[0036] Through the above combination of characteristics, the combination of the present invention has a better hair conditioning effect compared with other hair care products. BRIEF DESCRIPTION OF THE DRAWINGS

[0037] Figure 1 The test results of the sample of Example 1;

[0038] Figure 2 The test results of the sample of Example 2;

[0039] Figure 3 The test results of the sample of Example 3;

[0040] Figure 4 The test results of the sample of Example 4;

[0041] Figure 5 This is a photo of the chicken embryo experiment in Example 1;

[0042] Figure 6 This is a photo of the chicken embryo experiment in Example 2;

[0043] Figure 7 This is a photo of the chicken embryo experiment in Example 3;

[0044] Figure 8 This is a photo of the chicken embryo after the positive control group experiment;

[0045] Fig. 9 This is a photo of the chicken embryo experiment in the negative control group. DETAILED DESCRIPTION

[0046] The technical solution of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0047] Source of raw materials:

[0048] Hydrolyzed sericin (hereinafter referred to as hydrolyzed sericin solution to avoid confusion): InnoSeriCARE (hair care) hydrolyzed sericin, hydrolyzed sericin content 4wt%; Jiyuanhui (Shanghai) Biotechnology Research Co., Ltd.;

[0049] Hydrolyzed silk fibroin (hereinafter referred to as hydrolyzed silk fibroin solution to avoid confusion): InnoSeriCARE-soluble silk fibroin, hydrolyzed sericin content 2 wt%; Muscle Source Hui (Shanghai) Biotechnology Research Co., Ltd.

[0050] Part I

[0051] Examples and Comparative Examples

[0052] The preparation process of the embodiments and comparative examples of the present invention is as follows:

[0053] 1. Weigh and measure the oil-soluble hair conditioning agent, dissolve it in an oil bath at high temperature and mix it evenly to obtain an oil phase;

[0054] 2. Mix the hydrolyzed sericin solution, the hydrolyzed silk fibroin solution and glycerol, add weighed emulsifiers such as polyglyceryl-2 isostearate and PEG-7 glyceryl cocoate into deionized water, mix the two evenly to obtain an aqueous phase, and heat the aqueous phase to 80°C;

[0055] 3. Add the oil phase to the water phase, and then use a high-speed stirrer to emulsify for 5 minutes at 3000 rpm; cool the emulsion to 60°C, stir at a low speed for 2 hours, and the water-insoluble oil-soluble components spontaneously assemble into stable transparent micelles under the action of the hydrophilic surfactant;

[0056] The formula is shown in Table 1;

[0057] Table 1 Formula Unit: g

[0058]

[0059]

[0060] Part II Performance Test

[0061] Test Item 1: Safety Test

[0062] 1. Experimental Principle

[0063] The chorioallantoic membrane (CAM) is a respiratory membrane that surrounds the chicken embryo. Since the surface of the chicken embryo chorioallantoic membrane is rich in blood vessels and can be regarded as a complete organism, this test uses the characteristics of the complete, clear and transparent vascular system of the chorioallantoic membrane of the mid-stage incubated chicken embryo. A certain amount of the test substance is directly exposed to the chicken embryo chorioallantoic membrane. After the specified time, the changes in the toxic effect indicators of the chorioallantoic membrane (such as bleeding, coagulation and vascular melting) are observed, and scores are given. The mathematical mean value is calculated to evaluate the eye irritation of the test substance.

[0064] 2. Experimental Materials

[0065] Fertilized chicken embryos of Bailaihang chicken (Beijing Boehringer), Examples 1-3, and sterile physiological saline.

[0066] 3. Sample information

[0067] The test samples are Example 1, Example 2 and Example 3;

[0068] 4. Experimental methods

[0069] 4.1 Sample preparation

[0070] According to the addition ratio in Table 2, each test sample was prepared, with 0.9% NaCl solution as the negative control and 0.1Mol / L NaOH solution as the positive control.

[0071] 4.2 Eye irritation test steps

[0072] 1) Chicken embryo hatching:

[0073] Temperature: 37.6 degrees Celsius; Humidity: 45%-60%; Turntable frequency: 3 times / h-6 times / h; No need to rotate at 9 days old, and egg candling inspection should be carried out at 9 days old.

[0074] 2) CAM preparation.

[0075] 3) For each group, at least 4 chicken embryos were used to take 0.3 ml of undiluted liquid test substance.

[0076] 4) For liquid test substances, after applying to the CAM, allow the reaction to continue for 3 minutes, then gently rinse with saline (30 seconds), and then observe the reaction of the CAM (observe the degree of change of each toxic effect).

[0077] Based on the observed phenomena on the CAM membrane, the results of each test sample were evaluated as shown in Table 2. Figures 5 to 9 ; Figure 5 This is a photo of the chicken embryo experiment in Example 1; Figure 6 This is a photo of the chicken embryo experiment in Example 2; Figure 7 This is a photo of the chicken embryo experiment in Example 3; Figure 8 This is a photo of the chicken embryo after the positive control group experiment; Fig. 9 This is a photo of the chicken embryo after the experiment for the negative control group;

[0078] Table 2 Results evaluation

[0079] Sample name Stimulus score Irritation classification Example 1 0 Non-irritating Example 2 0 Non-irritating Example 3 0 Non-irritating Positive Control 18 Strong irritation Negative control 0 Non-irritating

[0080] It can be concluded from the results in the above table that Examples 1-3 are not irritating to the eyes.

[0081] Test Item 2: Combing Force Test

[0082] Test instrument: SK-7A vertical combing machine

[0083] Test method:

[0084] ①Use K12, soak at 60 degrees for one hour, scrub vigorously, repeat 3-4 times, and let the hair dry naturally;

[0085] ② Fix the standard hair bundle to the combing machine through the clamp, and start combing with the comb 15 times;

[0086] ③ Start the one-way spray and comb your hair 5 times;

[0087] ④Stop showering and start combing again 15 times;

[0088] ⑤Evenly apply 3g of shampoo sample on the standard hair bundle and comb it 15 times without flushing; ⑥Comb it 10 times while starting the one-way spray;

[0089] ⑦ Stop showering and start combing again 15 times;

[0090] ⑧ After the standard hair bundle is dried naturally, comb it 15 times with a combing machine

[0091] The test results refer to Table 3;

[0092] Table 3 Combing force test results

[0093]

[0094] Result analysis:

[0095] Through the formula tests of the blank group and each embodiment and comparative example, compared with the blank group, the dry combing and wet combing performances of Example 1 are significantly improved; compared with Comparative Examples 1-3, the wet combing performances of Examples 1-3 do not show significant improvement; compared with Comparative Examples 1-3, the dry combing performances of Examples 1-3 are significantly improved.

[0096] The reason is that there is no obvious correlation between wet combing performance and hydrolyzed sericin and glycerin, and there is no relationship between wet combing performance and demulsification and film formation. The film formed during demulsification is not yet stable and will not make a substantial contribution to the wet combing performance. The main factor that contributes to the wet combing performance is the conditioner in the formula.

[0097] There is a clear correlation between dry combing performance and glycerin, hydrolyzed sericin, and hydrolyzed silk fibroin. Sericin and glycerin play a decisive role in dry combing performance. When silk fibroin is used, it can promote the conditioner to perform better. If the amount of glycerin is too low, there will be too little glycerin involved in film formation, affecting the efficacy of the conditioner.

[0098] It can be seen from Examples 6 and 7 that the use of silicone oil conditioning agents is an important factor in achieving good dry combing performance, but it is not recommended to add silicone oil conditioning agents in some formulations. From an application perspective, it is appropriate to choose to add or not add conditioning agents according to functional requirements.

[0099] Test Item 3: Hair breakage resistance test

[0100] Testing instrument: Intelligent hair tensile strength tester

[0101] Test method:

[0102] ① After fixing the hair, stretch it to a specific length and test the pulling force when the hair breaks. Measurement range: 5cm;

[0103] ② Soak the hair in 10 times diluted shampoo (40℃, 10 minutes) and shake it thoroughly;

[0104] ③ Rinse with tap water (40℃, 1 minute) and dry with a towel;

[0105] ④Stretch the hair to a specific length and test the pulling force when the hair breaks;

[0106] The test results can be found in Table 4;

[0107] Table 4 Hair breakage resistance test results

[0108]

[0109] Result analysis:

[0110] It can be seen from the blank group, the examples and the comparative examples that no obvious improvement is observed in the tensile strength.

[0111] Test Item 4: SEM Photo of Hair

[0112] Test instrument: Scanning electron microscope (model: KYKY-EM6200)

[0113] Test method:

[0114] ① Place the hair sample (2 g, 12 cm) into a 10-fold dilution of shampoo (bath ratio 1:10, 40°C, 10 minutes).

[0115] ② Rinse with tap water (40℃, 1 minute).

[0116] ③ Dry with a towel.

[0117] ④ Scanning electron microscope (SEM) observation

[0118] Test results are visible Figures 1 to 4 ; Figure 1 The test results of the sample of Example 1 are as follows: Figure 2 The test results of the sample of Example 2 are as follows: Figure 3 The test results of the sample of Example 3 are as follows: Figure 4 These are the test results for the samples of Example 4.

[0119] Figure 1 At the microscopic level, a more complete film deposition can be observed, with obvious deposition at the ends of the hair scales. Figures 2 to 4 There is also sedimentation, but the density of the sediment is not as high as Figure 1 .

[0120] Part 3 Application Formulation

[0121] The formula shown in this section is a fluffy and smooth shampoo, and its formula is shown in Table 5;

[0122] Table 5 Recipe

[0123]

[0124]

[0125] It will be apparent to those skilled in the art that the invention is not limited to the details of the exemplary embodiments described above and that the invention can be implemented in other specific forms without departing from the spirit or essential features of the invention. Therefore, the embodiments should be considered exemplary and non-limiting in all respects, and the scope of the invention is defined by the appended claims rather than the foregoing description, and it is intended that all variations falling within the meaning and scope of the equivalent elements of the claims be included in the invention. Any reference numeral in a claim should not be considered as limiting the claim to which it relates.

Claims

1. A hair care composition, characterized in that The composition is an oil-in-water emulsion system; The micelles in the oil-in-water emulsion system are coated with an oil-soluble hair conditioning agent; The oil-in-water emulsification system also includes glycerin, hydrolyzed sericin, and hydrolyzed silk fibroin; The weight ratio of the glycerol, hydrolyzed sericin and hydrolyzed silk fibroin is 5:0.004-0.02:0.002-0.

01.

2. The hair care composition according to claim 1, characterized in that The oil-soluble hair conditioning agent is one or more combinations of squalane, vegetable oil, organic siloxane, hydrogenated polyisobutene, hydrogenated polydecene, dioctyl carbonate, isododecane, isohexadecane hydrogenated rosin acid methyl ester, trimethylolpropane tricaprylate / tricaprate.

3. The hair care composition according to claim 2, characterized in that The vegetable oil is one or more combinations of jojoba seed oil, meadowfoam seed oil, macadamia nut oil, shea butter, coconut oil, and argan oil; The organosiloxane is one or more combinations of polydimethylsiloxane, polydimethylsiloxane alcohol, amino-terminated polydimethylsiloxane, and phenyl polydimethylsiloxane.

4. The hair care composition according to claim 1, characterized in that In the oil-in-water emulsification system, the amount of the emulsifier used is 10-20 wt%.

5. The hair care composition according to claim 4, characterized in that The emulsifier is one or more combinations of polyglyceryl-2 isostearate, PEG-7 glyceryl cocoate, and PEG-30 hydrogenated castor oil.

6. The hair care composition according to claim 1, characterized in that In the water-in-oil emulsified system, the amount of the oil-soluble hair conditioning agent is 30 to 50 wt %; And / or, the concentration of glycerol in the oil-in-water emulsion system is 3-7 wt %.

7. Use of the hair care composition according to any one of claims 1 to 6 in preparing hair cosmetics.

8. The use according to claim 7, characterized in that The cosmetic is shampoo or conditioner.

9. A hair cosmetic, characterized in that: A hair care composition comprising the hair care composition according to any one of claims 1 to 6.

10. The hair cosmetic according to claim 9, characterized in that: The amount of the hair care composition is 0.1 to 5 wt%.

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