Device for removing thrombus

Abstract

The invention provides a thrombus removing device which comprises an outer catheter, a blood vessel expansion mechanism, a developing tube and a suction assembly, the blood vessel expansion mechanism is installed in the outer catheter in a sliding mode, and the suction assembly used for sucking and removing broken thrombus is connected to the outer catheter; the blood vessel expansion mechanism comprises an expansion rod, a rotating sleeve, an outer sliding sleeve and an arc-shaped cutter, the arc-shaped cutter is hinged between the expansion rod and the rotating sleeve, the expansion rod is hinged to the outer sliding sleeve, the rotating sleeve is slidably installed in the outer sliding sleeve, and the outer sliding sleeve is slidably installed in the outer catheter; one end of the outer sliding sleeve is connected with a first driving assembly for driving the arc-shaped cutter to open; a front net basket is arranged in the developing pipe, a core pushing pipe for pushing the front net basket out of the developing pipe is arranged in the developing pipe, and one end of the developing pipe is connected with a second driving assembly for driving the core pushing pipe. The thrombus removing device is scientific and reasonable in structural design, convenient to operate, good in using effect, small in damage to blood vessels, good in thrombus removing effect and capable of being used and popularized.

Description

Technical Field

[0001] The invention relates to a medical device, in particular to a device for removing thrombus. Background Art

[0002] Thrombosis refers to the abnormal coagulation of blood in blood vessels. Thrombosis can block blood vessels, resulting in blood flow obstruction, which in turn can cause serious health problems such as stroke, myocardial infarction, deep vein thrombosis, etc. Traditional treatments include drug thrombolysis, mechanical thrombectomy and surgery, but these methods all have certain risks and limitations. Therefore, the development of a device to remove thrombi is a solution for this type of patients.

[0003] Compared with traditional thrombus removal treatment methods, thrombus removal through device therapy has many advantages, including reducing patient trauma, shortening postoperative recovery time, accurately removing thrombi, reducing damage to surrounding healthy tissues, and reducing the risk of postoperative complications. These advantages make it one of the most promising options for treating venous thrombosis. However, some device treatments also have disadvantages, which may cause damage to blood vessels during thrombus removal, and even cause irreversible damage. For example, a rotary thrombus treatment device may cause mechanical damage to the inner wall of the blood vessel and induce new distal thrombi or emboli; a rheological thrombus removal device may not be able to completely remove thrombi, especially for larger or harder thrombi. At the same time, due to the use of high-speed liquid flow, fluid impact may cause vascular spasm or damage; an ultrasound-assisted thrombolysis device combines ultrasound and CT. Under long-term or high-intensity operation, the high-frequency vibration of ultrasound may cause damage to the inner wall of the blood vessel, resulting in poor treatment effects for certain types of thrombi (such as hard thrombi). Based on the defects of the above-mentioned similar devices, it is necessary to design a vascular robot that can avoid defects as much as possible and combine their respective advantages to clear thrombi. Summary of the invention

[0004] The technical problem to be solved by the present invention is to provide a device for removing blood clots in view of the above-mentioned deficiencies of the prior art. The device can completely remove the blood clots as a whole through the cooperation of the vascular expansion mechanism and the rotary cutting movement, with the auxiliary positioning of the developing tube. The device has a simple structure, convenient operation, accurate positioning and fast blood clot removal.

[0005] In order to solve the above technical problems, the technical solution adopted by the present invention is: a device for removing thrombus, characterized in that it comprises an outer catheter, a vascular expansion mechanism, a developing tube and a suction component, wherein the vascular expansion mechanism is slidably installed in the outer catheter, and the outer catheter is connected with a suction component for suctioning and clearing the broken thrombus;

[0006] The blood vessel expansion mechanism comprises an expansion rod, a rotating sleeve, an outer sliding sleeve and an arc-shaped cutter, wherein the arc-shaped cutter is hinged between the expansion rod and the rotating sleeve, the expansion rod is hinged on the outer sliding sleeve, the rotating sleeve is slidably installed in the outer sliding sleeve, the outer sliding sleeve is slidably installed in the outer catheter, and one end of the outer sliding sleeve is connected to a first driving component for driving the arc-shaped cutter to open;

[0007] A front net basket is arranged in the developing tube, a core push tube for pushing the front net basket out of the developing tube is arranged in the developing tube, and one end of the developing tube is connected to a second driving assembly for driving the core push tube;

[0008] The suction assembly comprises a suction pump and a storage bag, wherein the storage bag is connected to an external catheter via the suction pump.

[0009] Preferably, the first driving assembly includes a screw motor and a first ball screw nut pair, the first ball screw nut pair is connected to an outer sliding sleeve, and the screw motor is transmission-connected to a screw in the first ball screw nut pair.

[0010] Preferably, the second drive assembly comprises a brushless motor, a bevel gear set and a second ball screw nut pair, the output shaft of the brushless motor is keyed to the bevel gear set, and the bevel gear set is connected to the core push tube via the second ball screw nut pair.

[0011] Preferably, a deep groove ball bearing is arranged at the end shoulder position of the outer sliding sleeve, an elastic retaining ring for fixing the inner ring of the deep groove ball bearing is installed on the outer sliding sleeve, the outer ring of the deep groove ball bearing is interference fit connected with a supporting rotating ring, and four expansion rods are equidistantly hinged on the supporting rotating ring.

[0012] Preferably, a rear mesh basket is extruded and installed between the outer sliding sleeve and the outer catheter, and a front mesh basket is extruded and installed at the inner end of the developing tube. Both the front mesh basket and the rear mesh basket are mesh structures formed by weaving nickel-titanium alloy wires through heat setting. When the front mesh basket and the rear mesh basket are in the open state, they are spherical in shape and have a large contact surface with the blood vessel wall.

[0013] Preferably, an inner sliding sleeve is installed between the rotating sleeve and the outer sliding sleeve, the rotating sleeve is connected to the inner sliding sleeve through a frameless motor, the rotating sleeve is connected to the inner ring of the frameless motor through an interference fit through a bushing, the outer ring of the frameless motor is fixedly connected to the shoulder of the inner sliding sleeve, a slider is provided on the inner sliding sleeve, and a sliding groove cooperating with the slider is opened on the inner wall of the outer sliding sleeve.

[0014] Preferably, the liquid inlet port of the suction pump is connected to the external catheter through a suction input tube, a suction valve is provided on the suction input tube, and the liquid outlet port of the suction pump is connected to the storage bag through an output tube.

[0015] Preferably, a delivery port for the outer sliding sleeve to enter is opened at the end of the outer guide tube, a sliding port for the rotating sleeve to enter is opened at the end of the outer sliding sleeve, and a rotating port for the developing tube to enter is opened at the end of the rotating sleeve.

[0016] Preferably, the ultrasonic generator is connected to the developing tube through an ultrasonic transmission ring, the developing tube is filled with ultrasonic gel for ultrasonic transmission, the brushless motor and the bevel gear set are fixedly mounted on the supporting base, and the developing tube is provided with a thrombolytic drug input port connected to the core push tube inside the developing tube.

[0017] Preferably, the developing tube is driven through the thrombus first, and the ultrasonic generator can be used for preliminary thrombolysis. After the front net basket passes through the thrombus, it is unfolded to collect the broken thrombus. Then the screw motor drives the outer sliding sleeve to adjust the arc-shaped tool to the required diameter, and at the same time drives the rear net basket to unfold to collect the broken thrombus. Then the rotating shaft is driven to perform rotary cutting movement, and finally the thrombolytic drug is delivered for coordination.

[0018] Compared with the prior art, the present invention has the following advantages:

[0019] 1. The present invention can reduce the damage to blood vessels when clearing thrombus: the basket in the present invention is in an open state in the blood vessel to intercept and shred the thrombus. The basket will not cause damage to the blood vessel, and plays a role in intercepting the fine thrombus generated during the cutting process, so as to avoid the shredded thrombus being unable to be intercepted and removed from the blood vessel in time, which may cause distal vascular embolism. The arc-shaped tool is used to shred the thrombus, the ultrasonic generator ultrasonically assists in thrombus shredding, and the thrombolytic drug enters from the thrombolytic drug input port to cooperate with thrombolysis. The suction component forms a negative pressure to suck the shredded thrombus to complete thrombus removal and cleaning. The thrombus removal efficiency is high, and there is no need for multiple reciprocating movements in the blood vessel, which reduces the probability of damage to the blood vessel.

[0020] 2. The present invention can improve the efficiency of thrombus removal and has high safety: Compared with the overall pull-out thrombus removal method, the present invention uses an arc-shaped cutter driven by a frameless motor to achieve the purpose of clot cutting. Compared with manual cutting, electric cutting has higher efficiency, can greatly reduce the overall time of interventional treatment, has high efficiency, and the cutting range gradually changes from small to large, making the thrombus removal safer.

[0021] 3. The present invention is applicable to thrombi of different sizes and reduces the probability of mechanical damage. The present invention designs an expansion rod in the expansion mechanism, and drives the outer sliding sleeve through a screw motor to adjust the rotational expansion movement of the expansion rod, thereby controlling the arc-shaped tool to expand to the required diameter size, and can realize the rotational cutting and shredding of thrombi of different diameters, thereby avoiding the mechanical damage to the inner wall of the blood vessel caused by the rotary thrombus treatment device.

[0022] 4. The present invention can effectively dissolve softer thrombi by combining the vibration generated by the ultrasonic generator with the liquid medicine. In addition, ultrasonic vibration can accelerate the penetration and dissolution process of the liquid medicine, thereby improving the treatment efficiency. For harder thrombi, the arc-shaped tool is driven to expand to the required diameter, and the thrombi in the blood vessel are rotationally removed by rotating the rotary sleeve, thereby avoiding damage to the surface of the blood vessel during rotational removal, and significantly reducing the risk of surgery and the probability of complications. At the same time, while the thrombi are rotationally removed, the liquid medicine can be used to further dissolve the thrombi, ensuring that the thrombi are completely removed, thereby improving the treatment effect. In addition, the removed thrombi are collected by the rear basket and the front basket to prevent them from being free in the blood vessels, thereby avoiding the formation of secondary thrombi. This dual collection mechanism greatly reduces the risk of postoperative thrombus re-formation, thereby improving the success rate of surgery and the safety of patients.

[0023] The present invention is further described in detail below with reference to the accompanying drawings and embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a schematic diagram of the overall front view half-section structure of the present invention.

[0025] Figure 2 It is an enlarged schematic diagram of the front end portion of the present invention.

[0026] Figure 3 It is an enlarged schematic diagram of the rear end portion of the present invention.

[0027] Figure 4 This is a three-dimensional structural diagram of the vascular dilation mechanism of the present invention.

[0028] Figure 5 It is a semi-sectioned three-dimensional structural schematic diagram of the vascular dilation mechanism part of the present invention.

[0029] Figure 6 It is a schematic diagram of the structure of the present invention when working in a blood vessel.

[0030] Description of reference numerals:

[0031] 1—arc-shaped tool; 2—elastic retaining ring; 3—support rotating ring;

[0032] 4—deep groove ball bearing; 5—expansion rod; 6—rear basket;

[0033] 7—rotating sleeve; 8—developing tube; 9—front basket;

[0034] 10—outer sliding sleeve; 11—shaft sleeve; 12—inner sliding sleeve;

[0035] 13—frameless motor; 14—external guide tube; 15—screw motor;

[0036] 16—first ball screw nut pair; 17—delivery port; 18—sliding port;

[0038] 19—rotating port; 20—suction valve; 21—suction inlet pipe;

[0039] 22—output tube; 23—storage bag; 24—suction pump;

[0040] 25—thrombolytic drug inlet; 26—second ball screw nut pair; 27—bevel gear set;

[0042] 28—brushless motor; 29—support base; 30—ultrasonic generator. DETAILED DESCRIPTION

[0043] like Figures 1 to 6 As shown, the present invention comprises an outer catheter 14, a vascular expansion mechanism, a developing tube 8 and a suction assembly. The vascular expansion mechanism is slidably installed in the outer catheter 14, and the outer catheter 14 is connected with a suction assembly for suctioning and cleaning broken thrombi.

[0044] The blood vessel expansion mechanism comprises an expansion rod 5, a rotating sleeve 7, an outer sliding sleeve 10 and an arc-shaped cutter 1, wherein the arc-shaped cutter 1 is hinged between the expansion rod 5 and the right end of the rotating sleeve 7, the expansion rod 5 is hinged on the front end of the outer sliding sleeve 10, the rotating sleeve 7 is slidably installed in the outer sliding sleeve 10, the outer sliding sleeve 10 is slidably installed in the outer catheter 14, and one end of the outer sliding sleeve 10 is connected to a first driving component for driving the arc-shaped cutter 1 to open;

[0045] A front mesh basket 9 is disposed at the front end of the developing tube 8, a core push tube for pushing the front mesh basket 9 out of the developing tube 8 is disposed inside the developing tube 8, and a second driving assembly for driving the core push tube is connected to the rear end of the developing tube 8;

[0046] The suction assembly includes a suction pump 24 and a storage bag 23 , and the storage bag 23 is connected to the outer catheter 14 via the suction pump 24 .

[0047] In this embodiment, the first driving assembly includes a screw motor 15 and a first ball screw nut pair 16 . The first ball screw nut pair 16 is connected to the outer sliding sleeve 10 , and the screw motor 15 is transmission-connected to the screw in the first ball screw nut pair 16 .

[0048] In this embodiment, the second drive assembly includes a brushless motor 28, a bevel gear set 27 and a second ball screw nut pair 26, the output shaft of the brushless motor 28 is keyed to the bevel gear set 27, and the bevel gear set 27 is connected to the core push tube through the second ball screw nut pair 26.

[0049] In this embodiment, a deep groove ball bearing 4 is arranged at the end shoulder position of the outer sliding sleeve 10, and an elastic retaining ring 2 for fixing the inner ring of the deep groove ball bearing 4 is installed on the outer sliding sleeve 10. The outer ring of the deep groove ball bearing 4 is connected with a support rotating ring 3 by interference fit, and four expansion rods 5 are equidistantly hinged on the support rotating ring 3. The outer sliding sleeve 10 is driven by a screw motor 15 to adjust the rotational expansion movement of the expansion rod 5, thereby controlling the arc-shaped tool 1 to expand to the required diameter size, so that thrombi of different diameters can be cut and shredded, thereby avoiding the mechanical damage to the inner wall of the blood vessel caused by the rotary thrombus treatment device.

[0050] In this embodiment, the rear mesh basket 6 is extruded and installed between the outer sliding sleeve 10 and the outer catheter 14, and the front mesh basket 9 is extruded and installed at the inner end of the developing tube 8. The front mesh basket 9 and the rear mesh basket 6 are both mesh structures formed by weaving nickel-titanium alloy wires through heat setting. When the front mesh basket 9 and the rear mesh basket 6 are in the open state, they are spherical in shape and have a large contact surface with the blood vessel wall.

[0051] In this embodiment, an inner sliding sleeve 12 is installed between the rotating sleeve 7 and the outer sliding sleeve 10, the rotating sleeve 7 is connected to the inner sliding sleeve 12 through a frameless motor 13, the rotating sleeve 7 is connected to the inner ring of the frameless motor 13 through an interference fit through a sleeve 11, the outer ring of the frameless motor 13 is fixedly connected to the shoulder of the inner sliding sleeve 12, a slider is provided on the inner sliding sleeve 12, and a sliding groove cooperating with the slider is opened on the inner wall of the outer sliding sleeve 10.

[0052] In this embodiment, the liquid inlet port of the suction pump 24 is connected to the external catheter 14 through a suction input pipe 21 , a suction valve 20 is provided on the suction input pipe 21 , and the liquid outlet port of the suction pump 24 is connected to the storage bag 23 through an output pipe 22 .

[0053] In this embodiment, a delivery port 17 is opened at the end of the outer guide tube 14 for the outer sliding sleeve 10 to enter, a sliding port 18 is opened at the end of the outer sliding sleeve 10 for the rotating sleeve 7 to enter, and a rotating port 19 is opened at the end of the rotating sleeve 7 for the developing tube 8 to enter.

[0054] In this embodiment, the ultrasonic generator 30 is connected to the left end of the developing tube 8 through an ultrasonic transmission ring. The developing tube 8 is filled with ultrasonic gel for ultrasonic transmission. The brushless motor 28 and the bevel gear set 27 are fixedly mounted on the support base 29. The developing tube 8 is provided with a thrombolytic drug input port 25 connected to the inner core push tube of the developing tube 8.

[0055] When in use, firstly, the outer catheter 14 is placed near the thrombus in the blood vessel, and the brushless motor 28 drives the bevel gear set 27 to move the delivery tube of the developing tube 8 to the thrombus. For softer thrombi, the robot delivers the thrombolytic solution to the thrombus through the thrombolytic drug inlet 25, and cooperates with the high-frequency vibration of the ultrasonic generator 30 to dissolve the thrombus.

[0056] For harder thrombi, the robot drives the bevel gear set 27 through the brushless motor 28 to move the core push tube in the developing tube 8 through the thrombi, and the core push rod pushes the front net basket 9 out of the developing tube 8, and the front net basket 9 automatically unfolds after being freed from the restraint of the developing tube 8. The outer sliding sleeve is driven to move slowly by the screw motor 15, and the outer sliding sleeve 10 pushes the rear net basket 6 to leave the outer catheter 14 and then automatically unfolds. Since the outer sliding sleeve 10 and the expansion rod 5 are hingedly connected, the expansion rod 5 will slowly rotate and lift up. After the arc-shaped tool 1 is expanded to the required size, the frameless motor 13 is started, and the frameless motor 13 is controlled to drive the rotating sleeve 7 to rotate. Due to the fixing effect of the supporting rotating ring 3 and the deep groove ball bearing 4, the arc-shaped tool 1 will be controlled to perform rotary cutting movement to remove harder thrombi. At the same time, the thrombolytic solution is delivered to the thrombus through the thrombolytic drug input port 25 to cooperate with thrombolysis. Then, the suction pump 24 of the suction assembly is started. After the suction pump 24 is turned on, negative pressure is formed in the outer catheter 14, and the thrombus fragments broken by the arc-shaped tool 1 are sucked into the storage bag 23, thereby achieving the purpose of clearing the thrombus and unblocking the blood vessels.

[0057] At the same time, the rear basket 6 and the front basket 9 are in an open state, which plays a role in intercepting and crushing the thrombus. After the arc-shaped cutter 1 finishes crushing the thrombus, the frameless motor 13 is turned off, the front basket 9 is pulled back into the developing tube 8 to return to the compressed state, and the outer sliding sleeve 10 and the rotating sleeve 7 are pulled to make the rear basket 6 return to the outer catheter 14 in a compressed state. At this time, the crushed thrombus in the two baskets can be taken out for convenient suction. Finally, the suction pump 24 is turned off, and the entire thrombus removal device is slowly withdrawn from the blood vessel, thus completing the thrombus removal operation.

[0058] The above is only a preferred embodiment of the present invention and does not limit the present invention in any way. Any simple modification, change and equivalent change made to the above embodiment according to the technical essence of the invention still falls within the protection scope of the technical solution of the present invention.

Claims

1. A device for removing blood clots, characterized in that: It comprises an outer catheter (14), a vascular expansion mechanism, a developing tube (8) and a suction assembly, wherein the vascular expansion mechanism is slidably mounted inside the outer catheter (14), and the suction assembly for suctioning and clearing broken thrombi is connected to the outer catheter (14); The blood vessel expansion mechanism comprises an expansion rod (5), a rotating sleeve (7), an outer sliding sleeve (10) and an arc-shaped cutter (1); the arc-shaped cutter (1) is hinged between the expansion rod (5) and the rotating sleeve (7); the expansion rod (5) is hinged on the outer sliding sleeve (10); the rotating sleeve (7) is slidably mounted in the outer sliding sleeve (10); the outer sliding sleeve (10) is slidably mounted in the outer catheter (14); one end of the outer sliding sleeve (10) is connected to a first driving component for driving the arc-shaped cutter (1) to open; A front net basket (9) is arranged in the developing tube (8), a core push tube for pushing the front net basket (9) out of the developing tube (8) is arranged in the developing tube (8), and one end of the developing tube (8) is connected to a second driving assembly for driving the core push tube; The suction assembly comprises a suction pump (24) and a storage bag (23), wherein the storage bag (23) is connected to the external catheter (14) via the suction pump (24); The first driving assembly comprises a screw motor (15) and a first ball screw nut pair (16), wherein the first ball screw nut pair (16) is connected to the outer sliding sleeve (10), and the screw motor (15) is transmission-connected to a screw in the first ball screw nut pair (16); The second driving assembly comprises a brushless motor (28), a bevel gear set (27) and a second ball screw nut pair (26); the output shaft of the brushless motor (28) is keyed to the bevel gear set (27), and the bevel gear set (27) is connected to the core push tube via the second ball screw nut pair (26); A deep groove ball bearing (4) is arranged at the end shoulder position of the outer sliding sleeve (10), an elastic retaining ring (2) for fixing the inner ring of the deep groove ball bearing (4) is installed on the outer sliding sleeve (10), the outer ring of the deep groove ball bearing (4) is connected with a supporting rotating ring (3) by interference fit, and four expansion rods (5) are equidistantly hinged on the supporting rotating ring (3); A rear mesh basket (6) is extruded and installed between the outer sliding sleeve (10) and the outer guide tube (14), and a front mesh basket (9) is extruded and installed at the inner end of the developing tube (8). Both the front mesh basket (9) and the rear mesh basket (6) are mesh structures formed by weaving nickel-titanium alloy wires through heat setting.

2. A device for removing blood clots according to claim 1, characterized in that: An inner sliding sleeve (12) is installed between the rotating sleeve (7) and the outer sliding sleeve (10); the rotating sleeve (7) is connected to the inner sliding sleeve (12) via a frameless motor (13); the rotating sleeve (7) is connected to the inner ring of the frameless motor (13) by interference fit via a shaft sleeve (11); the outer ring of the frameless motor (13) is fixedly connected to the shaft shoulder of the inner sliding sleeve (12); a sliding block is provided on the inner sliding sleeve (12); and a sliding groove cooperating with the sliding block is provided on the inner wall of the outer sliding sleeve (10).

3. The device for removing blood clots according to claim 1, characterized in that: The liquid inlet port of the suction pump (24) is connected to the external catheter (14) via a suction input pipe (21), a suction valve (20) is provided on the suction input pipe (21), and the liquid outlet port of the suction pump (24) is connected to the storage bag (23) via an output pipe (22).

4. The device for removing blood clots according to claim 1, characterized in that: The end of the outer guide tube (14) is provided with a delivery port (17) for the outer sliding sleeve (10) to enter, the end of the outer sliding sleeve (10) is provided with a sliding port (18) for the rotating sleeve (7) to enter, and the end of the rotating sleeve (7) is provided with a rotating port (19) for the developing tube (8) to enter.

5. The device for removing blood clots according to claim 1, characterized in that: The developing tube (8) is connected to an ultrasonic generator (30) via an ultrasonic transmission ring, the brushless motor (28) and the bevel gear set (27) are fixedly mounted on a support base (29), and a thrombolytic drug input port (25) connected to an inner core push tube of the developing tube (8) is provided on the developing tube (8).

Images