Aneurysm embolization device and delivery system

Abstract

The present invention relates to an aneurysm embolization device, comprising: a connecting wire, including a flexible section, an embolization section and a shaping section; the flexible section is located at one end of the connecting wire close to the distal end, the shaping section is located at one end of the connecting wire close to the proximal end, and the embolization section is located between the flexible section and the shaping section; the connecting wire is made of nickel-titanium alloy material; a guide spring is sleeved on the flexible section and connected to the connecting wire; the end of the guide spring close to the distal end is a hemispherical end; a developing wire is wound around the embolization section; a plurality of fiber pieces are all arranged on the developing wire and are arranged in sequence along the length direction of the connecting wire; a closing spring is sleeved on the shaping section; a first limiting ball is arranged on the shaping section of the connecting wire and is located at one end of the closing spring close to the proximal end. The above structure occupies a small space in the lumen of the microcatheter in a compressed state, and even if a fiber piece is arranged on the developing wire, it is still convenient to transport the aneurysm embolization device in the microcatheter. The present invention also relates to a conveying system.

Description

Technical Field

[0001] The present invention relates to the technical field of aneurysm occlusion equipment, and in particular to an aneurysm embolization device and a delivery system. Background Art

[0002] Aneurysms are injuries or lesions that occur in the arterial wall. They may occur in any part of the arterial system, but are more common in the main arteries of the limbs, the aorta, and the carotid arteries. Usually, aneurysms develop slowly, but as the aneurysm expands, the arterial wall becomes thinner and is prone to rupture. Once an aneurysm ruptures, it will seriously threaten the patient's life safety, especially the rupture of intracranial aneurysms, which leads to extremely high rates of mortality and disability in patients.

[0003] At present, open clipping surgery and endovascular interventional treatment are mostly used for aneurysms. Open clipping surgery requires craniotomy, which is very damaging to the body and has a long recovery period. Endovascular interventional treatment mainly uses various types of coils to embolize aneurysms, stent-assisted springs, and blood flow guidance to achieve treatment. The embolization coils are mainly bare embolization coils and fiber coils with fiber hair added to the bare embolization coils. These embolization coils have the following disadvantages:

[0004] 1. A single bare coil of embolization spring cannot effectively achieve dense embolization of aneurysms, especially for large aneurysms, which requires more bare coils of embolization springs.

[0005] 2. The fiber spring coil is mainly composed of fiber hairs randomly scattered on the bare coil of the embolic spring. The fiber hairs need to occupy a certain space, and the space of the microcatheter is limited, which greatly increases the difficulty of its delivery in the microcatheter. Summary of the invention

[0006] The present invention provides an aneurysm embolization device and a delivery system to solve the technical problem that the existing fiber spring coil is difficult to deliver in a microcatheter.

[0007] The invention discloses an aneurysm embolization device, which comprises a connecting wire, a guide spring, a developing wire, a plurality of fiber pieces, a closing spring, and a first limiting ball. The connecting wire comprises a flexible section, an embolization section, and a shaping section. The flexible section is located at one end of the connecting wire close to the distal end, the shaping section is located at one end of the connecting wire close to the proximal end, and the embolization section is located between the flexible section and the shaping section. The connecting wire is made of nickel-titanium alloy material. The guide spring is sleeved on the flexible section and connected to the connecting wire. One end of the guide spring close to the distal end is a hemispherical end. The developing wire is wound around the embolization section. The plurality of fiber pieces are all arranged on the developing wire and are sequentially spaced along the length direction of the connecting wire. The closing spring is sleeved on the shaping section. The first limiting ball is arranged on the shaping section of the connecting wire and is located at one end of the closing spring close to the proximal end.

[0008] When the aneurysm embolization device is in an expanded state, the flexible section is in a variable diameter spiral shape, and the guide spring is deformed along with the flexible section; the embolization section forms an embolization support body after expansion, and the developing wire is deformed along with the embolization section; the shaping section is in a variable diameter spiral shape, and the closing spring is deformed along with the shaping section; a part of the shaping section having a first limiting ball is located in the embolization support body, and one end of the shaping section having the first limiting ball is arranged toward the flexible section.

[0009] Furthermore, the fiber part includes a first fixing ring and fiber hairs, wherein the first fixing ring is arranged on the developing wire; one end of the fiber hairs is arranged on the first fixing ring, and the other end of the fiber hairs is arranged toward the flexible section.

[0010] Furthermore, the fiber part also includes fiber hair, one end of the fiber hair is arranged on the first fixing ring, and the other end of the fiber hair is arranged toward the flexible section; the fiber hair is shorter than the fiber hair; when the number of the fiber hair is multiple bundles, the multiple bundles of fiber hair are evenly arranged around the fiber hair.

[0011] Furthermore, the outer diameter of the first fixing ring is 0.2 mm to 0.4 mm; and the distance between two adjacent first fixing rings is 5 mm to 15 mm.

[0012] Furthermore, the guide spring is made of developing material, and its length is 10 mm to 20 mm.

[0013] Furthermore, the aneurysm embolization device also includes a second limiting ball, which is arranged on the shaping section of the connecting wire, and the diameter of the second limiting ball is smaller than the diameter of the first limiting ball; the second limiting ball is located at the end of the first limiting ball close to the proximal end.

[0014] Furthermore, when the aneurysm embolization device is in an expanded state, the embolization segments are wound into a spherical or quasi-spherical embolization support body; and the fiber pieces are used to fill the gaps between the embolization support bodies.

[0015] Furthermore, when the aneurysm embolization device is in an expanded state, the embolization segment expands into a spiral embolization support body; the fiber piece is arranged toward the axis of the embolization support body; and a part of the first limiting ball provided in the shaping segment enters into the embolization support body.

[0016] Furthermore, when the aneurysm embolization device is in an expanded state, the embolization segment expands into a spiral embolization support body, and the middle portion of the embolization support body protrudes outward in a direction away from the axis of the embolization support body; the fiber member is arranged toward the axis of the embolization support body; and the shaping segment is provided with a portion of the first limiting ball entering into the embolization support body.

[0017] The present invention also discloses a delivery system, which includes a microcatheter, a push wire and an aneurysm embolization device as described in any one of the above items, wherein the microcatheter includes a lumen; the aneurysm embolization device is disposed in the lumen; a limiting sleeve is disposed at one end of the push wire and is movably disposed in the lumen; the limiting sleeve is disposed on the first limiting ball or the second limiting ball of the aneurysm embolization device.

[0018] The aneurysm embolization device and delivery system provided by the present invention can achieve the following technical effects:

[0019] Compared with the prior art, the aneurysm embolization device disclosed in this embodiment makes full use of the characteristics of nickel-titanium alloy materials, so that the aneurysm embolization device disclosed in this embodiment has a compressed state suitable for transportation and an expanded state suitable for blocking aneurysms. The connecting wire made of nickel-titanium alloy material is used as the main body, and the guide spring, the developing wire, and the closing spring are sequentially arranged on the three parts of the flexible section, the embolization section and the shaping section of the connecting wire, and a plurality of fiber pieces are arranged on the developing wire. During the release process in the aneurysm, the flexible section of the connecting wire drives the guiding spring to expand and deform first to support the aneurysm top, and can also avoid scratching the aneurysm wall. The embolization section of the connecting wire drives the developing wire to expand and deform subsequently to support the aneurysm body. The shaping section of the connecting wire drives the closing spring to expand and deform into a variable diameter spiral state to block the aneurysm neck. Such a setting can ensure that the fiber piece is completely blocked in the aneurysm and will not enter the blood vessel.

[0020] The above structure occupies a small space in the lumen of the microcatheter in the compressed state. Even if a fiber piece is provided on the developing wire, it is still convenient for the aneurysm embolization device disclosed in this embodiment to be transported in the microcatheter. The embolization density of the aneurysm embolization device in the expanded state is also improved. The first place to improve the embolization density is that there is a double structural deformation at the same position, which is specifically manifested in the cooperation between the flexible segment and the guide spring, the cooperation between the embolization segment and the developing wire, and the cooperation between the shaping segment and the closing spring. The second place to improve the embolization density is that a fiber piece is also provided on the developing wire to fill the gap or internal space of the embolization support body formed by the expansion of the embolization segment. In addition, by providing a developing wire on the embolization segment of the connecting wire, it is not only convenient for the operator to observe the position of the aneurysm embolization device in the lumen of the microcatheter, but also convenient for the operator to observe the expansion state of the aneurysm embolization device after being released in the aneurysm. The first limiting ball is provided on the shaping segment to facilitate the delivery of the aneurysm embolization device in the microcatheter.

[0021] The foregoing general description and the following description are exemplary and explanatory only and are not intended to limit the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] One or more embodiments are exemplarily described by corresponding drawings, and these exemplary descriptions and drawings do not limit the embodiments. Elements with the same reference numerals in the drawings are regarded as similar elements, and wherein:

[0023] Figure 1 is a schematic diagram of an embodiment of an aneurysm embolization device of the present invention in a compressed state;

[0024] Figure 2 is a schematic diagram of an embodiment of a connecting wire of an aneurysm embolization device of the present invention;

[0025] Figure 3 is a schematic diagram of an embodiment of a fiber member of an aneurysm embolization device of the present invention;

[0026] Figure 4 FIG. 1 is a schematic diagram of an explosion of an embodiment of an aneurysm embolization device of the present invention in an expanded state. Figure 1 ;

[0027] Figure 5 is a top view schematic diagram of an embodiment of an aneurysm embolization device of the present invention, in which a flexible segment is in an expanded state;

[0028] Figure 6 is a top view schematic diagram of an embodiment of an aneurysm embolization device of the present invention, in which a shaping segment is in an expanded state;

[0029] Figure 7 FIG. 1 is a schematic diagram of an explosion of an embodiment of an aneurysm embolization device of the present invention in an expanded state. Figure 2 ;

[0030] Figure 8 FIG. 1 is a schematic diagram of an explosion of an embodiment of an aneurysm embolization device of the present invention in an expanded state. Figure 3 ;

[0031] Fig. 9 It is a partial cross-sectional schematic diagram of an embodiment of a delivery system of the present invention in a release process;

[0032] Fig.10 Schematic diagram of an embodiment of an aneurysm embolization device of the present invention in an expanded state Figure 1 ;

[0033] Fig.11 Schematic diagram of an embodiment of an aneurysm embolization device of the present invention in an expanded state Figure 2 .

[0034] Reference numerals:

[0035] 1. Connecting wire; 11. Flexible section; 12. Embolization section; 13. Shaping section; 14. Embolization support; 21. Guide spring; 22. Development wire; 23. Closing spring; 3. Fiber piece; 31. First fixing ring; 32. Fiber hair; 33. Fiber sub-hair; 41. First limiting ball; 42. Second limiting ball; 5. Microcatheter; 51. Tube cavity; 6. Push wire; 61. Limiting sleeve; 62. Second fixing ring. DETAILED DESCRIPTION

[0036] In order to be able to understand the features and technical contents of the embodiments of the present invention in more detail, the implementation of the embodiments of the present invention is described in detail below in conjunction with the accompanying drawings. The attached drawings are for reference only and are not used to limit the embodiments of the present invention. In the following technical description, for the convenience of explanation, a full understanding of the disclosed embodiments is provided through multiple details. However, one or more embodiments can still be implemented without these details. In other cases, to simplify the drawings, well-known structures and devices can be simplified for display.

[0037] The terms "first", "second", etc. in the description and claims of the embodiments of the present invention and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that the terms used in this way can be interchanged where appropriate, so that the embodiments of the embodiments of the present invention described here. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions.

[0038] In the embodiments of the present invention, the terms "upper", "lower", "inside", "middle", "outside", "front", "back" and the like indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings. These terms are mainly used to better describe the embodiments of the present invention and its embodiments, and are not used to limit the indicated devices, elements or components to have a specific direction, or to be constructed and operated in a specific direction. Moreover, in addition to being used to indicate directions or positional relationships, some of the above terms may also be used to indicate other meanings. For example, the term "upper" may also be used to indicate a certain dependency or connection relationship in some cases. For those of ordinary skill in the art, the specific meanings of these terms in the embodiments of the present invention can be understood according to the specific circumstances.

[0039] In addition, the terms "disposed", "connected", and "fixed" should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral structure; it can be a mechanical connection, or an electrical connection; it can be a direct connection, or an indirect connection through an intermediate medium, or it can be an internal connection between two devices, elements, or components. For those of ordinary skill in the art, the specific meanings of the above terms in the embodiments of the present invention can be understood according to specific circumstances.

[0040] Unless otherwise specified, the term "plurality" means two or more and "plurality" means two or more.

[0041] It should be noted that, in the absence of conflict, the embodiments and features in the embodiments of the present invention may be combined with each other.

[0042] In the present invention, the distal end refers to the end away from the operator during surgery, and the proximal end refers to the end close to the operator during surgery.

[0043] First embodiment

[0044] The aneurysm embolization device mentioned in this embodiment, such as Figure 1 , Figure 2 As shown, the aneurysm embolization device includes a connecting wire 1, a guide spring 21, a developing wire 22, a plurality of fiber pieces 3, a closing spring 23, and a first limiting ball 41. In order to facilitate the introduction of the structure of the aneurysm embolization device, the structure of the aneurysm embolization device when it is in a compressed state is introduced. The connecting wire 1 is made of nickel-titanium alloy material, and the connecting wire 1 includes three parts, which are a flexible section 11, an embolization section 12, and a shaping section 13. The flexible section 11 is located at one end of the connecting wire 1 close to the distal end, the shaping section 13 is located at one end of the connecting wire 1 close to the proximal end, and the embolization section 12 is located between the flexible section 11 and the shaping section 13. The guide spring 21 is made of developing material, and one end of the guide spring 21 is a hemispherical end to avoid scratching the inner wall of the blood vessel. The guide spring 21 is sleeved on the flexible section 11 of the connecting wire 1, and the guide spring 21 is fixedly connected to the flexible section 11 of the connecting wire 1. The hemispherical end of the guide spring 21 is located at the end of the flexible section 11 of the connecting wire 1 close to the distal end, the developing wire 22 is spirally wound around the embolization section 12 of the connecting wire 1, and multiple fiber pieces 3 are arranged on the developing wire 22, and multiple fiber pieces 3 are arranged in sequence along the length direction of the connecting wire 1. The closing spring 23 can be made of developing material. The closing spring 23 is sleeved on the shaping section 13 of the connecting wire 1, and both ends of the closing spring 23 are fixedly connected to the shaping section 13 of the connecting wire 1. The first limiting ball 41 is arranged on the shaping section 13 of the connecting wire 1, and the first limiting ball 41 is located at the end of the closing spring 23 close to the proximal end.

[0045] like Figure 1 , Figure 3As shown, the fiber piece 3 includes a first fixing ring 31 and a bundle of fiber hairs 32. The first fixing ring 31 is arranged on the developing wire 22. One end of the bundle of fiber hairs 32 is arranged on the end surface of the first fixing ring 31 facing the flexible section 11, and the other end of the bundle of fiber hairs 32 is arranged toward the flexible section 11 of the connecting wire 1. The outer diameter of the first fixing ring 31 is 0.2mm to 0.4mm, and both ends of the first fixing ring 31 are rounded to avoid damaging the aneurysm wall during the release of the aneurysm embolization device. On the developing wire 22, the distance between two adjacent first fixing rings 31 is 5mm to 15mm, that is, the distance between two adjacent fiber pieces 3 is 5mm to 15mm.

[0046] Optionally, the length of the guide spring 21 is 10 mm to 20 mm. By limiting the length of the guide spring 21 , it is possible to prevent the guide spring 21 from damaging the inner wall of the blood vessel.

[0047] Optionally, the first limiting ball 41 may be made of developing material.

[0048] In the present invention, the developing material may be any one of platinum-iridium alloy, platinum-tungsten alloy and tantalum alloy.

[0049] The aneurysm embolization device disclosed in this embodiment has three different structures in the expanded state, as follows:

[0050] Optional, such as Figure 1 , Figure 4 , Figure 5 As shown, the flexible section 11 is in a variable diameter spiral shape after expansion. When the flexible section 11 is in a variable diameter spiral shape, the diameter of the end of the flexible section 11 close to the proximal end is larger than the diameter of the end of the flexible section 11 close to the distal end. The guide spring 21 disposed on the flexible section 11 also deforms with the flexible section 11 and is in a variable diameter spiral shape. Figure 1 , Figure 4 As shown, the embolization segment 12 forms a spherical or quasi-spherical embolization support body 14 after expansion. Figure 4 The dotted circle in the middle indicates the edge of the spherical embolic support 14. The developing wire 22 arranged on the embolic segment 12 also deforms into a spherical or quasi-spherical shape along with the embolic segment 12. The multiple fiber pieces 3 arranged on the developing wire 22 are used to fill the gaps between the embolic support 14. A part of the spherical or quasi-spherical embolic support 14 enters the space of the variable diameter spiral flexible segment 11. Figure 1 , Figure 4 , Figure 6As shown, the shaping section 13 is in a variable diameter spiral shape after expansion. When the shaping section 13 is in a variable diameter spiral state, the closing spring 23 arranged on the shaping section 13 is also deformed with the shaping section 13 to be in a variable diameter spiral shape. A part of the shaping section 13 in a variable diameter spiral shape provided with the first limiting ball 41 enters into the embolic support body 14. At this time, one end of the shaping section 13 provided with the first limiting ball 41 is arranged toward the flexible section 11 in a variable diameter spiral shape. The diameter of one end of the shaping section 13 provided with the first limiting ball 41 is smaller than the diameter of one end of the shaping section 13 close to the proximal end.

[0051] Optional, such as Figure 1 , Figure 5 , Figure 7 As shown, the flexible section 11 is in a variable diameter spiral shape after expansion. When the flexible section 11 is in a variable diameter spiral shape, the diameter of the end of the flexible section 11 close to the proximal end is larger than the diameter of the end of the flexible section 11 close to the distal end. The guide spring 21 disposed on the flexible section 11 also deforms with the flexible section 11 and is in a variable diameter spiral shape. Figure 1 , Figure 7 As shown, the embolization section 12 forms a spiral embolization support body 14 after expansion, and the developing wire 22 arranged on the embolization section 12 also deforms into a spiral shape along with the embolization section 12. The multiple fiber pieces 3 arranged on the developing wire 22 are all arranged toward the axis of the embolization support body 14 and are used to fill the internal space of the embolization support body 14. Figure 1 , Figure 6 , Figure 7 As shown, the shaping section 13 is in a variable diameter spiral shape after expansion. When the shaping section 13 is in a variable diameter spiral state, the closing spring 23 arranged on the shaping section 13 is also deformed with the shaping section 13 to be in a variable diameter spiral shape. A part of the shaping section 13 in a variable diameter spiral shape provided with the first limiting ball 41 enters into the embolic support body 14. At this time, one end of the shaping section 13 provided with the first limiting ball 41 is arranged toward the flexible section 11 in a variable diameter spiral shape. The diameter of one end of the shaping section 13 provided with the first limiting ball 41 is smaller than the diameter of one end of the shaping section 13 close to the proximal end.

[0052] Optional, such as Figure 1 , Figure 5 , Figure 8 As shown, the flexible section 11 is in a variable diameter spiral shape after expansion. When the flexible section 11 is in a variable diameter spiral shape, the diameter of the end of the flexible section 11 close to the proximal end is larger than the diameter of the end of the flexible section 11 close to the distal end. The guide spring 21 disposed on the flexible section 11 also deforms with the flexible section 11 and is in a variable diameter spiral shape. Figure 1 , Figure 8As shown, the embolization section 12 forms a spiral embolization support body 14 after expansion, and the middle part of the embolization support body 14 protrudes outward in a direction away from the axis of the embolization support body 14, and the developing wire 22 arranged on the embolization section 12 also deforms into a spiral shape along with the embolization section 12. The multiple fiber pieces 3 arranged on the developing wire 22 are all arranged toward the axis of the embolization support body 14 and are used to fill the internal space of the embolization support body 14. Figure 1 , Figure 6 , Figure 8 As shown, the shaping section 13 is in a variable diameter spiral shape after expansion. When the shaping section 13 is in a variable diameter spiral state, the closing spring 23 arranged on the shaping section 13 is also deformed with the shaping section 13 to be in a variable diameter spiral shape. A part of the shaping section 13 in a variable diameter spiral shape provided with the first limiting ball 41 enters into the embolic support body 14. At this time, one end of the shaping section 13 provided with the first limiting ball 41 is arranged toward the flexible section 11 in a variable diameter spiral shape. The diameter of one end of the shaping section 13 provided with the first limiting ball 41 is smaller than the diameter of one end of the shaping section 13 close to the proximal end.

[0053] You can choose any one of the above three technical solutions.

[0054] Compared with the prior art, the aneurysm embolization device disclosed in this embodiment makes full use of the characteristics of nickel-titanium alloy materials, so that the aneurysm embolization device disclosed in this embodiment has a compressed state suitable for transportation and an expanded state suitable for blocking aneurysms. The connecting wire 1 made of nickel-titanium alloy material is used as the main body, and the guide spring 21, the developing wire 22, and the closing spring 23 are sequentially arranged on the three parts of the flexible section 11, the embolization section 12 and the shaping section 13 of the connecting wire 1, and a plurality of fiber pieces 3 are arranged on the developing wire 22. During the release process in the aneurysm, the flexible section 11 of the connecting wire 1 drives the guiding spring 21 to expand and deform first to support the aneurysm top, and can also avoid scratching the aneurysm wall. The embolization section 12 of the connecting wire 1 drives the developing wire 22 to expand and deform subsequently to support the aneurysm body, and the shaping section 13 of the connecting wire 1 drives the closing spring 23 to expand and deform into a variable diameter spiral state to block the aneurysm neck. Such a setting can ensure that the fiber piece 3 is completely blocked in the aneurysm and will not enter the blood vessel.

[0055] The above structure occupies a small space in the tube cavity 51 of the microcatheter 5 in the compressed state. Even if the fiber piece 3 is arranged on the developing wire 22, it is still convenient for the aneurysm embolization device disclosed in this embodiment to be transported in the microcatheter 5. The embolization density of the aneurysm embolization device in the expanded state is also improved. The first place to improve the embolization density is that there are double structural deformations at the same position, which are specifically manifested as the cooperation between the flexible section 11 and the guide spring 21, the cooperation between the embolization section 12 and the developing wire 22, and the cooperation between the shaping section 13 and the closing spring 23. The second place to improve the embolization density is that the fiber piece 3 is also arranged on the developing wire 22 to fill the gap or internal space of the embolization support body 14 formed by the expansion of the embolization section 12. In addition, by arranging the developing wire 22 on the embolization section 12 of the connecting wire 1, it is not only convenient for the operator to observe the position of the aneurysm embolization device in the tube cavity 51 of the microcatheter 5, but also convenient for the operator to observe the expansion state of the aneurysm embolization device after being released in the aneurysm. The first limiting ball 41 is provided on the shaping section 13 to facilitate the delivery of the aneurysm embolization device in the microcatheter 5 .

[0056] Second embodiment

[0057] This embodiment also proposes an aneurysm embolization device. The second embodiment is a further improvement on the first embodiment, and is specifically as follows:

[0058] Optional, such as Figure 3 As shown, the fiber member 3 further includes a bundle of fiber hairs 33, one end of which is arranged on the end surface of the first fixing ring 31 facing the flexible section 11, and the other end of which is arranged toward the flexible section 11. The bundle of fiber hairs 33 is arranged on one side of the fiber hairs 32, and the length of the fiber hairs 33 is shorter than the length of the fiber hairs 32. Such an arrangement can not only increase the embolization density of the aneurysm embolization device in the expanded state, but also facilitate the delivery of the aneurysm embolization device in the compressed state.

[0059] Alternatively, if Figure 3 As shown, the fiber member 3 further includes a plurality of bundles of fiber hairs 33, one end of each of which is disposed on the end surface of the first fixing ring 31 facing the flexible section 11, and the other end of each of which is disposed toward the flexible section 11. The plurality of bundles of fiber hairs 33 are evenly arranged around the fiber hairs 32, and the length of the fiber hairs 33 is shorter than that of the fiber hairs 32. Such an arrangement can not only increase the embolization density of the aneurysm embolization device in the expanded state, but also facilitate the delivery of the aneurysm embolization device in the compressed state.

[0060] Third embodiment

[0061] This embodiment also proposes an aneurysm embolization device. The third embodiment is a further improvement based on the first or second embodiment, and is specifically as follows:

[0062] Optional, such as Figure 1 , Figure 4 , Figure 6 As shown, the aneurysm embolization device also includes a second limiting ball 42, which is arranged on the shaping section 13 of the connecting wire 1, and the second limiting ball 42 is located at the end of the first limiting ball 41 close to the proximal end. The second limiting ball 42 can be made of a developing material, which is convenient for the operator to observe the position of the second limiting ball 42 and then judge the release of the aneurysm embolization device. The diameter of the second limiting ball 42 is smaller than the inner diameter of the limiting sleeve 61, and the inner diameter of the limiting sleeve 61 is smaller than or equal to the diameter of the first limiting ball 41, that is, the diameter of the second limiting ball 42 is smaller than the diameter of the first limiting ball 41, which can ensure that the second limiting ball 42 can smoothly detach from the limiting sleeve 61 of the push wire 6 after the aneurysm embolization device is pushed out of the microcatheter 5 in the later stage.

[0063] Fourth embodiment

[0064] A conveying system mentioned in this embodiment, such as Figure 1 , Fig. 9 As shown, the delivery system includes a microcatheter 5, a push wire 6, and an aneurysm embolization device disclosed in any one of the first to third embodiments. The microcatheter 5 has a lumen 51 inside. A limiting sleeve 61 is provided at one end of the push wire 6, and the limiting sleeve 61 is provided at one end of the push wire 6 close to the distal end through a second fixing ring 62, and is movably provided in the lumen 51 of the microcatheter 5. When in use, the aneurysm embolization device is provided in the lumen 51 of the microcatheter 5, and the limiting sleeve 61 at one end of the push wire 6 is sleeved on the first limiting ball 41 or the second limiting ball 42 of the aneurysm embolization device.

[0065] Application scenario of an exemplary embodiment:

[0066] like Figure 1 , Figure 3 , Figure 4 , Figure 5 , Figure 6 , Fig.10As shown, the aneurysm embolization device and the push wire 6 are arranged in the microcatheter 5, and the limiting sleeve 61 of the push wire 6 is sleeved on the second limiting ball 42, and the end of the limiting sleeve 61 close to the distal end abuts against the first limiting ball 41. After the microcatheter 5 enters the blood vessel, the end of the microcatheter 5 close to the distal end first enters the aneurysm, and the end of the push wire 6 provided with the limiting sleeve 61 moves toward the distal end, and the soft segment first loses the restriction of the microcatheter 5. The connecting wire 1 is made of nickel-titanium alloy material. Since nickel-titanium alloy has the characteristics of memory metal, the soft segment first begins to expand, and the flexible segment 11 is in a variable diameter spiral shape after expansion. As shown in the figure, when the flexible segment 11 is in a variable diameter spiral state, the diameter of the end of the flexible segment 11 close to the embolization segment 12 is greater than the diameter of the end of the flexible segment 11 close to the distal end, and the guide spring 21 arranged on the flexible segment 11 also deforms with the flexible segment 11 to be in a variable diameter spiral shape. Afterwards, the end of the push wire 6 provided with the limiting sleeve 61 continues to move toward the distal end, and the embolization section 12 loses the restriction of the microcatheter 5, and the embolization section 12 also begins to expand and entangle, and forms a spherical or quasi-spherical embolization support 14, and the developing wire 22 provided on the embolization section 12 also deforms into a spherical or quasi-spherical shape along with the embolization section 12. The multiple fiber pieces 3 provided on the developing wire 22 are used to fill the gaps between the embolization support bodies 14. A part of the spherical or quasi-spherical embolization support body 14 enters the space of the flexible section 11 in the shape of a variable diameter spiral. Then, the end of the push wire 6 provided with the limiting sleeve 61 continues to move toward the distal end, and the shaping section 13 loses the restriction of the microcatheter 5. The shaping section 13 begins to expand and is released from the limiting sleeve 61 of the push wire 6. After expansion, the shaping section 13 is in a variable diameter spiral shape. As shown in the figure, when the shaping section 13 is in a variable diameter spiral shape, the diameter of the end of the shaping section 13 provided with the first limiting ball 41 is smaller than the diameter of the end of the shaping section 13 close to the embolization section 12, and the closing spring 23 provided on the shaping section 13 is also deformed with the shaping section 13 to be in a variable diameter spiral shape. A part of the shaping section 13 provided with the first limiting ball 41 in the variable diameter spiral shape enters the embolization support body 14. At this time, the end of the shaping section 13 provided with the first limiting ball 41 is arranged toward the flexible section 11 in the variable diameter spiral shape. However, due to the limitation of the aneurysm wall, the shaping segment 13 uses the portion entering the embolization support body 14 as a fixed portion, and the remaining portion of the shaping segment 13 deforms toward the direction of the soft segment and covers a portion of the embolization support body 14 .

[0067] Application scenario of another exemplary embodiment:

[0068] like Figure 1 , Figure 3 , Figure 5 , Figure 6 , Figure 7 , Fig.11As shown, the aneurysm embolization device and the push wire 6 are arranged in the microcatheter 5, and the limiting sleeve 61 of the push wire 6 is sleeved on the second limiting ball 42, and the end of the limiting sleeve 61 close to the distal end abuts against the first limiting ball 41. After the microcatheter 5 enters the blood vessel, the end of the microcatheter 5 close to the distal end first enters the aneurysm, and the end of the push wire 6 provided with the limiting sleeve 61 moves toward the distal end, and the soft segment first loses the restriction of the microcatheter 5. The connecting wire 1 is made of nickel-titanium alloy material. Since nickel-titanium alloy has the characteristics of memory metal, the soft segment first begins to expand, and the flexible segment 11 is in a variable diameter spiral shape after expansion. As shown in the figure, when the flexible segment 11 is in a variable diameter spiral state, the diameter of the end of the flexible segment 11 close to the embolization segment 12 is greater than the diameter of the end of the flexible segment 11 close to the distal end, and the guide spring 21 arranged on the flexible segment 11 also deforms with the flexible segment 11 to be in a variable diameter spiral shape. Afterwards, the end of the push wire 6 provided with the limiting sleeve 61 continues to move toward the distal end, and the embolization section 12 loses the restriction of the microcatheter 5, and the embolization section 12 also begins to expand and deform, and forms a spiral embolization support body 14, and the developing wire 22 provided on the embolization section 12 also deforms into a spiral shape along with the embolization section 12. The multiple fiber pieces 3 provided on the developing wire 22 are all arranged toward the axis of the embolization support body 14, and are used to fill the internal space of the embolization support body 14. Then, the end of the push wire 6 provided with the limiting sleeve 61 continues to move toward the distal end, and the shaping section 13 loses the restriction of the microcatheter 5. The shaping section 13 begins to expand and is released from the limiting sleeve 61 of the push wire 6. After expansion, the shaping section 13 is in a variable diameter spiral shape. As shown in the figure, when the shaping section 13 is in a variable diameter spiral shape, the diameter of the end of the shaping section 13 provided with the first limiting ball 41 is smaller than the diameter of the end of the shaping section 13 close to the embolization section 12, and the closing spring 23 provided on the shaping section 13 is also deformed with the shaping section 13 to be in a variable diameter spiral shape. A part of the shaping section 13 provided with the first limiting ball 41 in the variable diameter spiral shape enters the embolization support body 14. At this time, the end of the shaping section 13 provided with the first limiting ball 41 is arranged toward the flexible section 11 in the variable diameter spiral shape.

[0069] Application scenario of another exemplary embodiment:

[0070] like Figure 1 , Figure 3 , Figure 5 , Figure 6 , Figure 8 , Fig.11As shown, the aneurysm embolization device and the push wire 6 are arranged in the microcatheter 5, and the limiting sleeve 61 of the push wire 6 is sleeved on the second limiting ball 42, and the end of the limiting sleeve 61 close to the distal end abuts against the first limiting ball 41. After the microcatheter 5 enters the blood vessel, the end of the microcatheter 5 close to the distal end first enters the aneurysm, and the end of the push wire 6 provided with the limiting sleeve 61 moves toward the distal end, and the soft segment first loses the restriction of the microcatheter 5. The connecting wire 1 is made of nickel-titanium alloy material. Since nickel-titanium alloy has the characteristics of memory metal, the soft segment first begins to expand, and the flexible segment 11 is in a variable diameter spiral shape after expansion. As shown in the figure, when the flexible segment 11 is in a variable diameter spiral state, the diameter of the end of the flexible segment 11 close to the embolization segment 12 is greater than the diameter of the end of the flexible segment 11 close to the distal end, and the guide spring 21 arranged on the flexible segment 11 also deforms with the flexible segment 11 to be in a variable diameter spiral shape. Afterwards, the end of the push wire 6 provided with the limiting sleeve 61 continues to move toward the distal end, and the embolization section 12 loses the restriction of the microcatheter 5, and the embolization section 12 also begins to expand and deform, and forms a spiral embolization support body 14, and the middle part of the embolization support body 14 protrudes outward in a direction away from the axis of the embolization support body 14, and the developing wire 22 provided on the embolization section 12 also deforms into a spiral shape along with the embolization section 12, and the middle part of the developing wire 22 also protrudes outward in a direction away from the axis of the embolization support body 14. The multiple fiber pieces 3 provided on the developing wire 22 are all provided toward the axis of the embolization support body 14, and are used to fill the internal space of the embolization support body 14. Then, the end of the push wire 6 provided with the limiting sleeve 61 continues to move toward the distal end, and the shaping section 13 loses the restriction of the microcatheter 5. The shaping section 13 begins to expand and is released from the limiting sleeve 61 of the push wire 6. After expansion, the shaping section 13 is in a variable diameter spiral shape. As shown in the figure, when the shaping section 13 is in a variable diameter spiral shape, the diameter of the end of the shaping section 13 provided with the first limiting ball 41 is smaller than the diameter of the end of the shaping section 13 close to the embolization section 12, and the closing spring 23 provided on the shaping section 13 is also deformed with the shaping section 13 to be in a variable diameter spiral shape. A part of the shaping section 13 provided with the first limiting ball 41 in the variable diameter spiral shape enters the embolization support body 14. At this time, the end of the shaping section 13 provided with the first limiting ball 41 is arranged toward the flexible section 11 in the variable diameter spiral shape.

[0071] The above description and the accompanying drawings fully illustrate the embodiments of the present invention so that those skilled in the art can practice them. Other embodiments may include structural and other changes. The embodiments represent only possible variations. Unless explicitly required, individual components and functions are optional, and the order of operations may vary. Parts and features of some embodiments may be included in or replace parts and features of other embodiments. The embodiments of the present invention are not limited to the structures described above and shown in the accompanying drawings, and various modifications and changes may be made without departing from the scope thereof. The scope of the present invention is limited only by the appended claims.

Claims

1. An aneurysm embolization device, characterized in that: include: The connecting wire (1) comprises a flexible section (11), an embolization section (12) and a shaping section (13); the flexible section (11) is located at an end of the connecting wire (1) close to the distal end, the shaping section (13) is located at an end of the connecting wire (1) close to the proximal end, and the embolization section (12) is located between the flexible section (11) and the shaping section (13); the connecting wire (1) is made of nickel-titanium alloy material; A guide spring (21) is sleeved on the flexible section (11) and connected to the connecting wire (1); an end of the guide spring (21) close to the distal end is a hemispherical end; A developing wire (22) wound around the embolization section (12); A plurality of fiber pieces (3), all arranged on the developing wire (22), and arranged in sequence and spaced apart along the length direction of the connecting wire (1); A closing spring (23) sleeved on the shaping section (13); A first limiting ball (41) is arranged on the shaping section (13) of the connecting wire (1) and is located at an end of the closing spring (23) close to the proximal end; When the aneurysm embolization device is in an expanded state, the flexible section (11) is in the shape of a variable diameter spiral, and the guide spring (21) is deformed along with the flexible section (11); the embolization section (12) forms an embolization support body (14) after expansion, and the developing wire (22) is deformed along with the embolization section (12); the shaping section (13) is in the shape of a variable diameter spiral, and the closing spring (23) is deformed along with the shaping section (13); a portion of the first limiting ball (41) provided in the shaping section (13) is located in the embolization support body (14), and one end of the first limiting ball (41) provided in the shaping section (13) is arranged toward the flexible section (11).

2. The aneurysm embolization device according to claim 1, characterized in that: The fiber member (3) comprises: A first fixing ring (31) is arranged on the developing wire (22); The fiber hair (32) has one end arranged on the first fixing ring (31) and the other end arranged toward the flexible section (11).

3. The aneurysm embolization device according to claim 2, characterized in that: The fiber member (3) further comprises: A fiber hair (33), one end of which is arranged on the first fixing ring (31) and the other end of which is arranged toward the flexible section (11); the fiber hair (33) is shorter than the fiber hair (32); When the number of the fiber hairs (33) is multiple bundles, the multiple bundles of fiber hairs (33) are evenly arranged around the fiber hairs (32).

4. The aneurysm embolization device according to claim 2, characterized in that: The outer diameter of the first fixing ring (31) is 0.2 mm to 0.4 mm; The distance between two adjacent first fixing rings (31) is 5 mm to 15 mm.

5. The aneurysm embolization device according to claim 1, characterized in that: The guide spring (21) is made of developing material and has a length of 10 mm to 20 mm.

6. The aneurysm embolization device according to claim 1, characterized in that: Also includes: The second limiting ball (42) is arranged on the shaping section (13) of the connecting wire (1), and the diameter of the second limiting ball (42) is smaller than the diameter of the first limiting ball (41); the second limiting ball (42) is located at an end of the first limiting ball (41) close to the proximal end.

7. The aneurysm embolization device according to any one of claims 1 to 6, characterized in that: When the aneurysm embolization device is in an expanded state, the embolization segment (12) is wound into a spherical or quasi-spherical embolization support body (14); the fiber piece (3) is used to fill the gaps between the embolization support bodies (14).

8. The aneurysm embolization device according to any one of claims 1 to 6, characterized in that: When the aneurysm embolization device is in an expanded state, the embolization section (12) expands into a spiral embolization support body (14); the fiber piece (3) is arranged toward the axis of the embolization support body (14); and a part of the first limiting ball (41) provided in the shaping section (13) enters into the embolization support body (14).

9. The aneurysm embolization device according to any one of claims 1 to 6, characterized in that: When the aneurysm embolization device is in an expanded state, the embolization segment (12) expands into a spiral embolization support body (14), and the middle portion of the embolization support body (14) protrudes outward in a direction away from the axis of the embolization support body (14); the fiber member (3) is arranged toward the axis of the embolization support body (14); and the shaping segment (13) is provided with a portion of the first limiting ball (41) entering into the embolization support body (14).

10. A conveying system, characterized in that: include: A microcatheter (5), comprising a lumen (51); The aneurysm embolization device according to any one of claims 1 to 9, arranged in the lumen (51); The push wire (6) has a limiting sleeve (61) at one end and is movably arranged in the lumen (51); the limiting sleeve (61) is sleeved on the first limiting ball (41) or the second limiting ball (42) of the aneurysm embolization device.

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