Antibacterial healing-promoting porous medical dressing and preparation method thereof

Abstract

The invention discloses an antibacterial healing-promoting porous medical dressing and a preparation method thereof, and relates to the technical field of medical dressings. The method comprises the steps of S1, foam material pretreatment, S2, dressing bag manufacturing, S3, foaming treatment, S4, curing processing and S5, surface treatment. According to the antibacterial healing-promoting porous medical dressing prepared through the processes S1-S5, the outer layer of a foam dressing is made of a hydrophobic material, the inner layer of the foam dressing is made of a hydrophilic material, the foam dressing has porosity, low surface tension, high elasticity, high plasticity and light weight, exudate of a wound surface is controlled by means of a transfer and absorption mechanism of water vapor, and the wound healing-promoting effect is achieved. The absorbability of the dressing on percolate can reach 10-15 times of the mass of the dressing, and the dressing is completely permeable to oxygen and carbon dioxide, can be used as a drug carrier, can be prepared into various thicknesses and has a better protection effect on wound surfaces.

Description

Technical Field

[0001] The invention relates to the technical field of medical dressings, in particular to an antibacterial and healing-promoting pore-rich medical dressing and a preparation method thereof. Background Art

[0002] Medical dressings are wound dressings, medical materials used to cover sores, wounds or other injuries. With the in-depth study of the pathophysiology of wound healing, people have a deeper understanding of the wound healing process, which has led to the continuous improvement and development of medical wound dressings. Compared with the early days, new wound care dressings have undergone revolutionary changes, and a variety of medical dressings with different properties are available for clinical nursing staff to choose from;

[0003] However, the porous medical dressings in the prior art still have some defects:

[0004] Although the foam dressing prepared by the prior art has a porous structure, the absorption capacity of the prepared dressing is poor. When the dressing is attached to the wound surface, the exudate on the wound surface overflows, which leads to the need to replace the dressing in a short time. At the same time, the dressing is easy to stick to the wound surface, and there is a certain pain when replacing it.

[0005] In view of the above problems, the inventors proposed an antibacterial and healing-promoting porous medical dressing and a preparation method thereof to solve the above problems. Summary of the invention

[0006] In order to solve the above problems, the purpose of the present invention is to provide an antibacterial and healing-promoting porous medical dressing and a preparation method thereof.

[0007] In order to solve the above technical problems, the present invention adopts the following technical solution: a method for preparing an antibacterial and healing-promoting porous medical dressing, comprising the following steps:

[0008] S1. Foam material pretreatment

[0009] First, cut the matrix material into blocks of appropriate size for later use;

[0010] S2. Make dressing pack

[0011] Put the matrix material into a mixing device, gradually add additives, and fully mix the matrix material and additives by stirring and heating to obtain a dressing bag;

[0012] S3, Foaming treatment

[0013] Inject the dressing pack into the foaming mold. During injection, control the injection speed and injection pressure to ensure the uniformity and stability of the dressing pack;

[0014] S4, curing process

[0015] Placing the foaming mold filled with the dressing pack in a constant temperature device to solidify the dressing pack in the foaming mold. During this process, the dressing pack will gradually harden and solidify to form the shape of the foaming mold to obtain a foam dressing;

[0016] S5. Surface treatment

[0017] After curing, the foam dressing is taken out from the foaming mold, and the foam dressing is cut into different shapes and sizes as needed, and the surface is plastically processed to improve the air permeability and water absorption of the foam dressing.

[0018] Preferably, in S1, the matrix material is any one of polyurethane and polyvinyl alcohol.

[0019] Preferably, in S3, the injection speed is 80-100 mm / s, and the injection pressure is 1.5-40 bar.

[0020] Preferably, in S4, the curing time is 120 to 180 seconds, and the curing temperature is 30 to 40°C.

[0021] Preferably, in S2, the specific steps of making the dressing pack are as follows:

[0022] A1: 55-85% of a matrix material, 20-40% of a foaming agent, 10-30% of a cross-linking agent and 1-5% of an additive are mixed and stirred to obtain a mixture;

[0023] A2: The obtained mixture is injected into a foaming mold, and the mixture in the foaming mold is foamed.

[0024] Preferably, in A1, the additives include an antimicrobial agent, an active agent, a wetting agent and a pigment.

[0025] The present invention also provides an antibacterial and healing-promoting pore-rich medical dressing prepared by the above preparation method.

[0026] Compared with the prior art, the present invention has the following beneficial effects:

[0027] 1. In the present invention, the antibacterial and healing-promoting porous medical dressing prepared by the S1-S5 process has an outer layer of a hydrophobic material and an inner layer of a hydrophilic material. The foam dressing has porosity, low surface tension, elasticity, strong plasticity, and is lightweight. It relies on the transport and absorption mechanism of water vapor to control the exudate from the wound surface. The absorption capacity of the exudate can reach 10-15 times the mass of the dressing itself. It is completely permeable to oxygen and carbon dioxide and can be used as a drug carrier. At the same time, it can be made into various thicknesses and has a good protective effect on the wound surface.

[0028] 2. In the present invention, the antibacterial and healing-promoting porous medical dressing prepared from S1-S5 has pores less than 20 μm, does not soak normal skin, does not adhere to wounds, heals without scabs, leaves no residue on the wound, is painless when replaced, reduces scar formation, and is suitable for burn wounds of varying degrees, various surgical incisions, and superficial trauma. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0030] Figure 1 The present invention is a flow chart of a method for preparing an antibacterial and healing-promoting porous medical dressing. DETAILED DESCRIPTION

[0031] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0032] Embodiment 1: Figure 1 As shown, the present invention provides a method for preparing an antibacterial and healing-promoting porous medical dressing, comprising the following steps:

[0033] S1. Foam material pretreatment

[0034] Firstly, the matrix material is cut into blocks of appropriate size, and the matrix material is polyurethane, which is set aside;

[0035] S2. Make dressing pack

[0036] Put the matrix material into a mixing device, gradually add additives, and fully mix the matrix material and additives by stirring and heating to obtain a dressing bag;

[0037] S3, Foaming treatment

[0038] Inject the dressing pack into the foaming mold at a speed of 80 mm / s and a pressure of 10 bar to ensure uniformity and stability of the dressing pack;

[0039] S4. Curing process

[0040] The foaming mold filled with the dressing pack is placed in a constant temperature device, and the dressing pack in the foaming mold is cured for 120 seconds at a curing temperature of 35°C. During this process, the dressing pack will gradually harden and solidify to form the shape of the foaming mold to obtain a foam dressing;

[0041] S5. Surface treatment

[0042] After curing, the foam dressing is taken out from the foaming mold, and the foam dressing is cut into different shapes and sizes as needed, and the surface is plastically processed to improve the air permeability and water absorption of the foam dressing.

[0043] In S2, the specific steps for making the dressing pack are as follows:

[0044] A1: 70% of a matrix material, 30% of a foaming agent, 15% of a cross-linking agent and 3% of an additive are mixed and stirred to obtain a mixture, wherein the additive comprises an antibacterial agent, an active agent, a wetting agent and a pigment;

[0045] A2: The obtained mixture is injected into a foaming mold, and the mixture in the foaming mold is foamed.

[0046] The present invention also provides an antibacterial and healing-promoting pore-rich medical dressing prepared by the above preparation method.

[0047] Embodiment 2: A method for preparing an antibacterial and healing-promoting porous medical dressing, comprising the following steps:

[0048] S1. Foam material pretreatment

[0049] Firstly, the matrix material is cut into blocks of appropriate size, and the matrix material is polyurethane, which is set aside;

[0050] S2. Make dressing pack

[0051] Put the matrix material into a mixing device, gradually add additives, and fully mix the matrix material and additives by stirring and heating to obtain a dressing bag;

[0052] S3, Foaming treatment

[0053] Inject the dressing pack into the foaming mold at a speed of 100 mm / s and a pressure of 15 bar to ensure uniformity and stability of the dressing pack;

[0054] S4, curing process

[0055] The foaming mold filled with the dressing pack is placed in a constant temperature device, and the dressing pack in the foaming mold is cured for 150 seconds at a curing temperature of 40°C. During this process, the dressing pack will gradually harden and solidify to form the shape of the foaming mold to obtain a foam dressing;

[0056] S5. Surface treatment

[0057] After curing, the foam dressing is taken out from the foaming mold, and the foam dressing is cut into different shapes and sizes as needed, and the surface is plastically processed to improve the air permeability and water absorption of the foam dressing.

[0058] In S2, the specific steps for making the dressing pack are as follows:

[0059] A1: 60% of a matrix material, 20% of a foaming agent, 20% of a cross-linking agent and 5% of an additive are mixed and stirred to obtain a mixture, wherein the additive comprises an antibacterial agent, an active agent, a wetting agent and a pigment;

[0060] A2: The obtained mixture is injected into a foaming mold, and the mixture in the foaming mold is foamed.

[0061] Embodiment 3: A method for preparing an antibacterial and healing-promoting porous medical dressing, comprising the following steps:

[0062] S1. Foam material pretreatment

[0063] Firstly, the matrix material is cut into blocks of appropriate size, and the matrix material is polyvinyl alcohol, and set aside;

[0064] S2. Make dressing pack

[0065] Put the matrix material into a mixing device, gradually add additives, and fully mix the matrix material and additives by stirring and heating to obtain a dressing bag;

[0066] S3, Foaming treatment

[0067] Inject the dressing pack into the foaming mold at a speed of 90 mm / s and a pressure of 25 bar to ensure uniformity and stability of the dressing pack;

[0068] S4. Curing process

[0069] The foaming mold filled with the dressing pack is placed in a constant temperature device, and the dressing pack in the foaming mold is cured. The curing time is 180 seconds and the curing temperature is 40°C. During this process, the dressing pack will gradually harden and solidify to form the shape of the foaming mold to obtain a foam dressing;

[0070] S5. Surface treatment

[0071] After curing, the foam dressing is taken out from the foaming mold, and the foam dressing is cut into different shapes and sizes as needed, and the surface is plastically processed to improve the air permeability and water absorption of the foam dressing.

[0072] In S2, the specific steps for making the dressing pack are as follows:

[0073] A1: 80% of a matrix material, 35% of a foaming agent, 30% of a cross-linking agent and 5% of an additive are mixed and stirred to obtain a mixture, wherein the additive comprises an antibacterial agent, an active agent, a wetting agent and a pigment;

[0074] A2: The obtained mixture is injected into a foaming mold, and the mixture in the foaming mold is foamed.

[0075] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include these modifications and variations.

Claims

1. A method for preparing an antibacterial and healing-promoting porous medical dressing, characterized in that: The following steps are involved: S1. Foam material pretreatment First, cut the matrix material into blocks of appropriate size for later use; S2. Make dressing pack Put the matrix material into a mixing device, gradually add additives, and fully mix the matrix material and additives by stirring and heating to obtain a dressing bag; S3, Foaming treatment Inject the dressing pack into the foaming mold. During injection, control the injection speed and injection pressure to ensure the uniformity and stability of the dressing pack; S4, curing process Placing the foaming mold filled with the dressing pack in a constant temperature device to solidify the dressing pack in the foaming mold. During this process, the dressing pack will gradually harden and solidify to form the shape of the foaming mold to obtain a foam dressing; S5. Surface treatment After curing, the foam dressing is taken out from the foaming mold, and the foam dressing is cut into different shapes and sizes as needed, and the surface is plastically processed to improve the air permeability and water absorption of the foam dressing.

2. The method for preparing an antibacterial and healing-promoting porous medical dressing according to claim 1, characterized in that: In S1, the matrix material is any one of polyurethane and polyvinyl alcohol.

3. The method for preparing an antibacterial and healing-promoting porous medical dressing according to claim 1, characterized in that: In S3, the injection speed is 80-100 mm / s, and the injection pressure is 1.5-40 bar.

4. The method for preparing an antibacterial and healing-promoting porous medical dressing according to claim 1, characterized in that: In S4, the curing time is 120 to 180 seconds, and the curing temperature is 30 to 40°C.

5. The method for preparing an antibacterial and healing-promoting porous medical dressing according to claim 1, characterized in that: In S2, the specific steps of making the dressing pack are as follows: A1: 55-85% of a matrix material, 20-40% of a foaming agent, 10-30% of a cross-linking agent and 1-5% of an additive are mixed and stirred to obtain a mixture; A2: The obtained mixture is injected into a foaming mold, and the mixture in the foaming mold is foamed.

6. The antibacterial and healing-promoting porous medical dressing and its preparation method as claimed in claim 5, characterized in that: In A1, the additives include antimicrobial agents, active agents, wetting agents and pigments.

7. An antibacterial and healing-promoting porous medical dressing prepared by the preparation method according to any one of claims 1 to 6.

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