Weeding composition containing mesosulfuron-methyl as well as preparation method and application of weeding composition

Abstract

The invention relates to the technical field of pesticide weeding, in particular to a mesosulfuron-containing weeding composition as well as a preparation method and application thereof. The mesosulfuron-methyl-containing weeding composition is prepared from the following components in percentage by mass: 1% of mesosulfuron-methyl, 18% of an emulsifier, 3% of a safener, 2.7% of a stabilizer, 1-3% of organic bentonite, 2-3% of white carbon black, 3-3.5% of a surfactant and the balance of soybean first-grade salad oil, the stabilizer is prepared by mixing triphenylethyl phenol polyether ammonium sulfate, a naphthalene sulfonate formaldehyde condensate and diatomite according to the mass ratio of 5: 7: 15, and the average particle size of the diatomite is 5.2 microns. The mesosulfuron-containing weeding composition provided by the invention has the advantages that the weeding effect is ensured, the environment safety, the crop safety and the economic cost are considered, and the mesosulfuron-containing weeding composition is an ideal herbicide choice.

Description

Technical Field

[0001] The present application relates to the technical field of pesticide weed control, and in particular to a herbicidal composition containing mesosulfuron-methyl and a preparation method and application thereof. Background Art

[0002] Wheat is the third largest food crop in my country after corn and rice, accounting for more than 20% of the country's total grain output. Therefore, ensuring continuous high wheat yields is of great significance to maintaining my country's grain self-sufficiency rate and ensuring national food security. However, wheat production faces many threats, among which weeds are one of the most important factors. The area of ​​wheat fields in my country with weed damage accounts for more than 90% of the cultivated area, and the yield loss is as high as 15%. At the same time, with the continuous increase in labor costs in my country, the use of herbicides to control weed damage in wheat fields has become a necessary measure for wheat production.

[0003] Methsulfuron-methyl is a sulfonylurea herbicide, which is mainly absorbed by the stems and leaves of plants, conducted through the phloem and xylem, and absorbed in small amounts through the soil, inhibiting the activity of acetolactate synthase in sensitive plants, resulting in the blockage of the synthesis of branched-chain amino acids, thereby inhibiting cell division and causing the death of sensitive plants. It can be used to control a variety of grass weeds in wheat fields, such as foxtail millet, wild oats, clover, bluegrass, hard grass, alkaligrass, multiflora ryegrass, lycopersicon esculentum, brome, candle grass, knotweed, and rush, but the control effect on broadleaf weeds is not ideal. In addition, when conventional methsulfuron-methyl is used as a herbicide in wheat fields, the methsulfuron content is 3%-4%, the methsulfuron content is high, the safety is low, and there is a hidden danger of phytotoxicity. Summary of the invention

[0004] The purpose of the present application is to provide a herbicidal composition containing mesosulfuron and its preparation method and application in view of the deficiencies of the current technology. The herbicidal composition containing mesosulfuron prepared in the present application not only has good control effect on resistant weeds and reduces the dosage of the agent, but also has good safety for wheat and no effect on subsequent crops. It is an ideal herbicide with broad application prospects. The surfactant can improve the adhesion and conductivity of mesosulfuron on the weed leaves in the wheat field, so that mesosulfuron can better adhere to the leaf surface and stem surface of the weeds, improve the control effect of mesosulfuron on weeds, and has good safety for wheat.

[0005] In the first aspect, the present application provides a herbicidal composition containing mesosulfuron-methyl, which adopts the following technical scheme: A herbicidal composition containing mesosulfuron is prepared from the following components by mass percentage: 1% mesosulfuron, 18% emulsifier, 3% safener, 2.7% stabilizer, 1-3% organic bentonite, 2-3% white carbon black, 3-3.5% surfactant, and first-grade soybean salad oil (complemented to 100%), wherein the stabilizer is prepared by mixing triphenyl phenol polyether ammonium sulfate, naphthalene sulfonate formaldehyde condensate and diatomaceous earth in a mass ratio of 5:7:15, and the average particle size of the diatomaceous earth is 5.2 μm.

[0006] By adopting the above technical scheme, mesosulfuron: as the main active ingredient, it is a sulfonylurea herbicide, which is absorbed and transmitted through the stems and leaves of plants, inhibits the activity of acetolactate synthase in sensitive plants, leads to the synthesis of branched-chain amino acids, thereby inhibiting cell division and causing the death of sensitive plants. It can be used to control a variety of grass weeds in wheat fields. Emulsifier: helps to evenly disperse mesosulfuron in water to form a stable emulsion, improve the adhesion and conductivity of the agent on the plant surface. Safener: has a synergistic effect with mesosulfuron, can improve the control effect of mesosulfuron on weeds, while reducing the hidden dangers of wheat damage, and improve wheat safety, yield and quality. Stabilizer (triphenylethylphenol polyether ammonium sulfate, naphthalene sulfonate formaldehyde condensate and diatomaceous earth): helps to maintain the stability of the agent, prevent the decomposition or failure of the active ingredients, and improve the comprehensive performance of the herbicidal composition. Among them, diatomaceous earth also has good adsorption properties, which helps the agent to adhere to the plant surface. Organic bentonite: has good adsorption and swelling properties, which helps the agent adhere to and conduct on the plant surface. White carbon black: has adsorption properties, which helps the agent adhere to the plant surface. Surfactant: can improve the adhesion and conductivity of methyl disulfone on the weed leaves in wheat fields, so that methyl disulfone can better adhere to the weed leaf and stem surfaces, and improve the control effect of methyl disulfone on weeds. First-grade soybean salad oil: as a solvent, it helps the dissolution and dispersion of the agent, and at the same time has a certain lubricating effect, which is beneficial to the adhesion and conduction of the agent on the plant surface. In summary, the herbicidal composition containing methyl disulfone in the present application achieves good control effect on resistant weeds through the synergistic effect of each component, reduces the dosage of the agent, improves the safety of wheat, has no effect on subsequent crops, and has broad application prospects.

[0007] Preferably, the preparation method of mesosulfuron-methyl comprises the following steps: S21, add 700g of dichloromethane and 35g of di(trichloromethyl)carbonate to a dry reaction bottle, stir, cool the solution to 3°C after the di(trichloromethyl)carbonate is dissolved, dropwise add the pyrimidineamine solution to the di(trichloromethyl)carbonate solution, stir for 35min after the addition, then dropwise add 100g of triethylamine, stir for 1h after the addition, to obtain solution A for standby use; control the temperature below 45°C during the reaction; S22, add 69g of 5-methanesulfonylaminomethyl-2-methoxycarbonylbenzenesulfonamide and 150g of dichloromethane to another dry reaction bottle, cool to 3°C, slowly add solution A under stirring, the reaction is exothermic, and the dropping speed of solution A is controlled so that the temperature of the system does not exceed 30°C; S23. After adding solution A, continue stirring for 3 hours, add 1L of deionized water, stir thoroughly, let stand to separate the layers, separate the organic phase, acidify the aqueous phase with 0.1L of 2M hydrochloric acid, filter the precipitated solid, and dry to obtain methyl disulfone with a purity of 99.5%.

[0008] By adopting the above technical solution, mesosulfuron is a highly effective herbicide with good control effect on resistant weeds. In the preparation process of the present application, high-purity mesosulfuron can be effectively obtained through specific chemical reaction steps.

[0009] Preferably, in step S21, the pyrimidineamine solution is prepared by dissolving 35 g of pyrimidineamine in 100 g of dichloromethane.

[0010] Preferably, the emulsifier is emulsifier 8801 produced by Nanjing Kehong Chemical Co., Ltd.

[0011] Preferably, the safener is at least one of mefenpyr-butyl, ethyl 5-phenyl-4,5-dihydroisoxazole-3-carboxylate and 5-aminolevulinic acid.

[0012] Preferably, the safener is prepared by mixing mefenpyr-butyl, ethyl 5-phenyl-4,5-dihydroisoxazole-3-carboxylate and 5-aminolevulinic acid in a mass ratio of 3:4:3.

[0013] By adopting the above technical scheme, the safener is prepared by mixing pyraclostrobin, 5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester and 5-aminolevulinic acid in a mass ratio of 3:4:3. The synergistic effect of these three compounds in the safener is mainly manifested in the following aspects: Improving the weed control effect of mesosulfuron-butyl: pyraclostrobin, 5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester and 5-aminolevulinic acid all have the effect of enhancing plant stress resistance, which can improve the weed control effect of mesosulfuron-butyl. Reducing the hidden danger of phytotoxicity to wheat: pyraclostrobin, 5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester and 5-aminolevulinic acid all have the ability to protect plants from drug damage, which can reduce the hidden danger of phytotoxicity to wheat caused by mesosulfuron-butyl. Improve wheat safety, yield and quality: pyraclostrobin, 5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester and 5-aminolevulinic acid all have the effect of promoting plant growth and development, and can improve wheat safety, yield and quality. In summary, the safener is prepared by mixing pyraclostrobin, 5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester and 5-aminolevulinic acid in a mass ratio of 3:4:3. Its role in this application is to enhance the weed control effect of methyl disulfone, reduce the hidden danger of wheat damage, and improve wheat safety, yield and quality.

[0014] Preferably, the surfactant is prepared by mixing lauryl alcohol polyethylene glycol ether acetal, alkylphenol polyoxyethylene ether phosphate and alkyl polyoxyethylene ether sulfonate in a mass ratio of 5:4:4.

[0015] By adopting the above technical scheme, surfactants play a vital role in the herbicidal composition containing mesosulfuron, because they can improve the adhesion and conductivity of mesosulfuron on the leaf surface of weeds. Through this improvement, mesosulfuron can better adhere to the leaf surface and stem surface of weeds, thereby improving its control effect on weeds. In addition, surfactants can also improve the safety of wheat and reduce the potential damage of the agent to wheat. The surfactant is prepared by mixing lauryl alcohol polyglycol ether acetal, alkylphenol polyoxyethylene ether phosphate and alkyl polyoxyethylene ether sulfonate in a mass ratio of 5:4:4. There is a synergistic effect between these three components, which jointly improves the herbicidal effect of mesosulfuron and the safety of wheat. Lauryl alcohol polyglycol ether acetal has good wettability and permeability, which can help mesosulfuron better adhere to the surface of weeds and promote its conduction in the plant body. Alkylphenol polyoxyethylene ether phosphate has excellent emulsification and dispersibility, which helps mesosulfuron to be evenly distributed on the surface of weeds and improves the efficacy. The alkyl polyoxyethylene ether sulfonate has good surface activity and stability, and can enhance the adhesion of mesosulfuron on the surface of weeds while reducing damage to wheat. In summary, through the synergistic effect of these three surfactants, the herbicidal composition containing mesosulfuron prepared in the present application not only has good control effect on resistant weeds and reduces the dosage of the agent, but also has good safety for wheat and no effect on subsequent crops. It is an ideal herbicide with broad application prospects.

[0016] Preferably, the average particle size of the white carbon black is 5 microns, and the average particle size of the organic bentonite is 325 meshes.

[0017] In a second aspect, the present application provides a method for preparing a herbicidal composition containing mesosulfuron-methyl, using the following technical scheme: As a general technical concept, the present application also provides a method for preparing the above-mentioned herbicidal composition containing methyl disulfone, comprising the following steps: according to the formula dosage, methyl disulfone, emulsifier, safener, stabilizer, organic bentonite, white carbon black, surfactant and soybean primary salad oil are mixed and stirred evenly to obtain the herbicidal composition containing methyl disulfone.

[0018] In a third aspect, the present application provides an application of a herbicidal composition containing mesosulfuron, using the following technical solution: As a general technical concept, the present application also provides the use of the above-mentioned herbicidal composition containing mesosulfuron-methyl for controlling annual weeds in winter wheat fields, using a stem and leaf spray method with a dosage of 60-100 mL per mu.

[0019] In summary, the beneficial technical effects of this application are: 1. Improve weed control effect: The surfactant improves the adhesion and conductivity of mesosulfuron on the weed leaves, allowing the agent to better act on the weeds and improve the control effect on grass weeds such as foxtail millet, wild oats, and sedge.

[0020] 2. Reduce the amount of medicine used: Due to the synergistic effect of mesosulfuron, safener, stabilizer and other ingredients in the composition, a good herbicidal effect can be achieved at a lower dosage, reducing the amount of chemical agents used.

[0021] 3. Improve crop safety: The addition of safeners not only improves the weed control effect, but also reduces the hidden dangers of pesticide damage to crops such as wheat, ensuring the growth safety and yield quality of crops.

[0022] 4. Environmentally friendly: Reducing the use of chemical pesticides helps to reduce the pollution pressure on the environment, and the composition has no adverse effects on subsequent crops, which is conducive to the sustainable development of agriculture.

[0023] 5. Wide application: The composition can be used to control a variety of grass weeds in wheat fields, and has a wide weed control spectrum and good application prospects.

[0024] 6. Good stability: Through the specific stabilizer formula, the stability of mesosulfuron in the preparation is ensured, the shelf life of the product is extended, and it is convenient for storage and use.

[0025] 7. Economic benefits: Due to its high weed control ability and safety to crops, farmers can reduce losses caused by weeds and reduce the increased costs caused by excessive use of chemicals, thereby improving economic benefits. DETAILED DESCRIPTION

[0026] The embodiments of the present application will be described in detail below in conjunction with the examples, but those skilled in the art will appreciate that the following examples are only used to illustrate the present application and should not be considered to limit the scope of the present application. If the specific conditions are not specified in the examples, they are carried out according to the conventional conditions or the conditions recommended by the manufacturer. If the manufacturer is not specified for the reagents or instruments used, they are all conventional products that can be purchased commercially. The emulsifier is purchased from Nanjing Kehong Chemical Co., Ltd., and the model is emulsifier 8801.

[0027] In the following examples, 1 portion means 100 g.

[0028] Preparation Example 1 Preparation of Mesosulfuron The preparation method of mesosulfuron-methyl comprises the following steps: S21, add 700g of dichloromethane and 35g of di(trichloromethyl)carbonate to a dry reaction bottle, stir, cool the solution to 3°C after the di(trichloromethyl)carbonate is dissolved, dropwise add pyrimidineamine solution (the pyrimidineamine solution is prepared by dissolving 35g of pyrimidineamine in 100g of dichloromethane) to the di(trichloromethyl)carbonate solution, stir for 35min after the addition, then dropwise add 100g of triethylamine, stir for 1h after the addition, and obtain solution A for standby use; control the temperature below 45°C during the reaction; S22, add 69g of 5-methanesulfonylaminomethyl-2-methoxycarbonylbenzenesulfonamide and 150g of dichloromethane to another dry reaction bottle, cool to 3°C, slowly add solution A under stirring, the reaction is exothermic, and the dropping speed of solution A is controlled so that the temperature of the system does not exceed 30°C; S23. After adding solution A, continue stirring for 3 hours, add 1L of deionized water, stir thoroughly, let stand to separate the layers, separate the organic phase, acidify the aqueous phase with 0.1L of 2M hydrochloric acid, filter the precipitated solid, and dry to obtain methyl disulfone with a purity of 99.5%. Example 1

[0029] A herbicidal composition containing mesosulfuron is prepared from the following components by mass percentage: 1% mesosulfuron, 18% emulsifier 8801, 3% safener, 2.7% stabilizer, 1% organic bentonite, 2% white carbon black, 3% surfactant, and first-grade soybean salad oil (complemented to 100%), wherein the stabilizer is prepared by mixing triphenyl phenol polyether ammonium sulfate, naphthalene sulfonate formaldehyde condensate and diatomaceous earth in a mass ratio of 5:7:15, the diatomaceous earth has an average particle size of 5.2 μm, the white carbon black has an average particle size of 5 microns, the organic bentonite has an average particle size of 325 meshes, the safener is 5-aminolevulinic acid, and the surfactant is prepared by mixing lauryl alcohol polyethylene glycol ether acetal, alkylphenol polyoxyethylene ether phosphate and alkyl polyoxyethylene ether sulfonate in a mass ratio of 5:4:4; the mesosulfuron is the mesosulfuron prepared in Preparation Example 1; The preparation method of the above-mentioned herbicidal composition containing mesosulfuron comprises the following steps: according to the formula dosage, mesosulfuron, emulsifier 8801, safener, stabilizer, organic bentonite, white carbon black, surfactant and first-grade soybean salad oil are mixed and stirred evenly to obtain the herbicidal composition containing mesosulfuron. Example 2

[0030] A herbicidal composition containing mesosulfuron is prepared from the following components by mass percentage: 1% mesosulfuron, 18% emulsifier 8801, 3% safener, 2.7% stabilizer, 3% organic bentonite, 3% white carbon black, 3.5% surfactant, and first-grade soybean salad oil is supplemented to 100%, wherein the stabilizer is prepared by mixing triphenyl phenol polyether ammonium sulfate, naphthalene sulfonate formaldehyde condensate and diatomaceous earth in a mass ratio of 5:7:15, the diatomaceous earth has an average particle size of 5.2 μm, the white carbon black has an average particle size of 5 microns, the organic bentonite has an average particle size of 325 meshes, the safener is 5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester, and the surfactant is prepared by mixing lauryl alcohol polyethylene glycol ether acetal, alkylphenol polyoxyethylene ether phosphate and alkyl polyoxyethylene ether sulfonate in a mass ratio of 5:4:4; the mesosulfuron is the mesosulfuron prepared in Preparation Example 1; The preparation method of the above-mentioned herbicidal composition containing mesosulfuron comprises the following steps: according to the formula dosage, mesosulfuron, emulsifier 8801, safener, stabilizer, organic bentonite, white carbon black, surfactant and first-grade soybean salad oil are mixed and stirred evenly to obtain the herbicidal composition containing mesosulfuron. Example 3

[0031] A herbicidal composition containing mesotrione, which is prepared from the following components by mass percentage: 1% mesotrione, 18% emulsifier 8801, 3% safener, 2.7% stabilizer, 2% organic bentonite, 2.5% white carbon black, 3.4% surfactant, and first-grade soybean salad oil (complemented to 100%), wherein the stabilizer is prepared by mixing triphenyl phenol polyether ammonium sulfate, naphthalene sulfonate formaldehyde condensate and diatomaceous earth in a mass ratio of 5:7:15, the diatomaceous earth has an average particle size of 5.2 μm, the white carbon black has an average particle size of 5 microns, the organic bentonite has an average particle size of 325 meshes, the safener is pyraclostrobin, and the surfactant is prepared by mixing lauryl alcohol polyethylene glycol ether acetal, alkylphenol polyoxyethylene ether phosphate and alkyl polyoxyethylene ether sulfonate in a mass ratio of 5:4:4; the mesotrione is the mesotrione prepared in Preparation Example 1; The preparation method of the above-mentioned herbicidal composition containing mesosulfuron comprises the following steps: according to the formula dosage, mesosulfuron, emulsifier 8801, safener, stabilizer, organic bentonite, white carbon black, surfactant and first-grade soybean salad oil are mixed and stirred evenly to obtain the herbicidal composition containing mesosulfuron. Example 4

[0032] The same as Example 3, except that: the safener is prepared by mixing mefenpyr-butyl, ethyl 5-phenyl-4,5-dihydroisoxazole-3-carboxylate and 5-aminolevulinic acid in a mass ratio of 3:4:3.

[0033] Comparative Example 1 The same as Example 4, except that the methyl disulfone was purchased from Hubei Kewode Chemical Co., Ltd. (CAS: 208465-21-8, purity 95%).

[0034] Comparative Example 2 The same as Example 4, except that the stabilizer is prepared by mixing triphenyl phenol polyether ammonium sulfate and diatomaceous earth in a mass ratio of 12:15.

[0035] Comparative Example 3 The same as Example 4, except that the stabilizer is prepared by mixing naphthalenesulfonate formaldehyde condensate and diatomaceous earth in a mass ratio of 12:15.

[0036] Comparative Example 4 The same as Example 4, except that the surfactant is lauryl alcohol polyethylene glycol ether acetal.

[0037] Comparative Example 5 The same as Example 4, except that the surfactant is alkylphenol polyoxyethylene ether phosphate.

[0038] Comparative Example 6 The same as Example 4, except that the surfactant is alkyl polyoxyethylene ether sulfonate.

[0039] Performance test: Experiment on the effect of weed control in wheat fields Refer to "Guidelines for Field Efficacy Tests of Pesticides (I) Control of Weeds in Wheat Crops with Herbicides" (GB / T17980.41-2000).

[0040] The test site is Liangjiawu Village, Panggezhuang Town, Daxing District, Beijing. The wheat field soil is sandy loam with medium fertility and flat land. The test crop is winter wheat, the variety is Agricultural University 211, and the previous crop of the test site is rice.

[0041] Test targets: Common weeds in wheat fields, mainly including Alopecurus mume, Hard grass, Chickweed, Chickweed, Shepherd's purse, Artemisia selengensis, and Cyperus difformis.

[0042] Experimental design: A total of 11 treatments were set up in the experiment, and the herbicidal compositions containing mesosulfuron prepared in Examples 1 to 4 and Comparative Examples 1 to 6 and clean water (control area) were tested. All experimental plots were arranged in random blocks, with a plot area of ​​40 m 2 , each treatment was repeated 4 times.

[0043] Application time: The test was carried out by spraying the stems and leaves when the weeds were in the 3rd and 4th stages. The application equipment was a 3WBD backpack electric sprayer with a spray pressure of 0.5 MPa. The dosage of the herbicidal composition containing methyl disulfone was 90 mL per mu, and it was diluted with 10 L of water before spraying.

[0044] Test investigation method: observe the wheat damage at 15d and 30d after application - safety investigation: grade and score each test plot according to the damage classification method: grade 1, normal crop growth, no damage symptoms; grade 2, slight damage to crops, less than 3% damage; grade 3, moderate damage to crops, which can be recovered later and will not affect the yield; grade 4, severe damage to crops, difficult to recover, resulting in reduced yield; grade 5, severe damage to crops, unable to recover, resulting in significant reduction or total yield; using the absolute value investigation method, 15d, 30d, 45d after application, randomly sample 4 points in each test plot, 0.25m at each point 2 The plant protection efficacy in each test plot was investigated, and the fresh weight was measured 45 days after application to calculate the fresh weight protection efficacy.

[0045] Calculation method:

[0046]

[0047] The test results are shown in Table 1.

[0048] Wheat yield: After the wheat matured, the number of ears was investigated in each experimental plot, the yield was measured by threshing, and the thousand-grain weight was measured. The test results are shown in Table 1.

[0049] Table 1 Test results and yield of weed control effect on wheat fields

[0050] Analyzing the data in Table 1, we can see that: 1) The herbicidal composition containing mesosulfuron-methyl prepared in Examples 1 to 4 not only has a good control effect on weeds and reduces the dosage of the agent, but also has good safety for wheat and no effect on subsequent crops. It is an ideal herbicide with broad application prospects and can improve the yield and quality of wheat.

[0051] 2) The performance comparison analysis of the herbicidal composition containing mesosulfuron prepared in combination with Example 4 and Example 1-Example 3 shows that the safener is prepared by mixing pyraclostrobin, 5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester and 5-aminolevulinic acid in a mass ratio of 3:4:3. The synergistic effect between these three compounds can further enhance the control effect of mesosulfuron on weeds: pyraclostrobin, 5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester and 5-aminolevulinic acid all have the effect of enhancing plant stress resistance, which can enhance the control effect of mesosulfuron on weeds. Reduce the hidden danger of phytotoxicity to wheat: pyraclostrobin, 5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester and 5-aminolevulinic acid all have the ability to protect plants from drug damage, which can reduce the hidden danger of phytotoxicity of mesosulfuron to wheat. Improve wheat safety, yield and quality: pyraclostrobin, 5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester and 5-aminolevulinic acid all have the effect of promoting plant growth and development, and can improve wheat safety, yield and quality. In summary, the safener is prepared by mixing pyraclostrobin, 5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester and 5-aminolevulinic acid in a mass ratio of 3:4:3, which can significantly improve the weed control effect of methyl disulfone, reduce the hidden dangers of wheat damage, and improve wheat safety, yield and quality.

[0052] 3) The comparative analysis of the performance of the herbicidal composition containing mesosulfuron prepared in combination with Example 3 and Comparative Example 1 shows that the high-purity mesosulfuron prepared in the present application is a highly effective herbicide with good control effect on resistant weeds, and is superior to mesosulfuron on the market.

[0053] 4) The performance comparison analysis of the herbicidal composition containing mesosulfuron prepared in combination with Example 3 and Comparative Examples 2-3 shows that the stabilizer is prepared by mixing triphenyl phenol polyether ammonium sulfate, naphthalene sulfonate formaldehyde condensate and diatomaceous earth in a mass ratio of 5:7:15. The synergistic effect between triphenyl phenol polyether ammonium sulfate and naphthalene sulfonate formaldehyde condensate can significantly improve the weed control effect of the herbicidal composition and the safety of wheat, and at the same time can increase the yield of wheat.

[0054] 5) The performance comparison analysis of the herbicidal composition containing mesosulfuron prepared in combination with Example 3 and Comparative Examples 4-6 shows that the surfactant is prepared by mixing lauryl alcohol polyethylene glycol ether acetal, alkylphenol polyoxyethylene ether phosphate and alkyl polyoxyethylene ether sulfonate in a mass ratio of 5:4:4. The surfactant plays a vital role in the herbicidal composition containing mesosulfuron because they can improve the adhesion and conductivity of mesosulfuron on the leaf surface of weeds. Through this improvement, mesosulfuron can better adhere to the leaf surface and stem surface of weeds, thereby improving its control effect on weeds. In addition, the surfactant can also improve the safety of wheat and reduce the potential damage of the agent to wheat. Utilizing the synergistic effect between these three surfactants, the herbicidal composition containing mesosulfuron prepared in the present application not only has a good control effect on resistant weeds, reduces the dosage of the agent, but also has good safety for wheat and no effect on subsequent crops. It is an ideal herbicide with broad application prospects.

[0055] The above embodiments are only used to explain the technical solutions of the present application rather than to limit them. Although the above embodiments provide a specific description of the present application, relevant technical personnel should understand that the specific implementation modes of the present invention can still be modified or replaced by equivalents, and any modifications and equivalent replacements that do not depart from the spirit and scope of the present application should be included in the scope of protection of the present application.

Claims

1. A herbicidal composition containing mesosulfuron, characterized in that: The invention is prepared from the following components in percentage by mass: 1% methyl disulfone, 18% emulsifier, 3% safener, 2.7% stabilizer, 1-3% organic bentonite, 2-3% white carbon black, 3-3.5% surfactant, and first-grade soybean salad oil (complemented to 100%), wherein the stabilizer is prepared by mixing triphenyl phenol polyether ammonium sulfate, naphthalene sulfonate formaldehyde condensate and diatomaceous earth in a mass ratio of 5:7:15, and the average particle size of the diatomaceous earth is 5.2 μm.

2. A herbicidal composition containing mesosulfuron-methyl according to claim 1, characterized in that: The preparation method of mesosulfuron-methyl comprises the following steps: S21, add 700g of dichloromethane and 35g of di(trichloromethyl)carbonate to a dry reaction bottle, stir, cool the solution to 3°C after the di(trichloromethyl)carbonate is dissolved, dropwise add the pyrimidineamine solution to the di(trichloromethyl)carbonate solution, stir for 35min after the addition, then dropwise add 100g of triethylamine, stir for 1h after the addition, to obtain solution A for standby use; control the temperature below 45°C during the reaction; S22, add 69g of 5-methanesulfonylaminomethyl-2-methoxycarbonylbenzenesulfonamide and 150g of dichloromethane to another dry reaction bottle, cool to 3°C, slowly add solution A under stirring, the reaction is exothermic, and the dropping speed of solution A is controlled so that the temperature of the system does not exceed 30°C; S23. After adding solution A, continue stirring for 3 hours, add 1L of deionized water, stir thoroughly, let stand to separate the layers, separate the organic phase, acidify the aqueous phase with 0.1L of 2M hydrochloric acid, filter the precipitated solid, and dry to obtain methyl disulfone with a purity of 99.5%.

3. A herbicidal composition containing mesosulfuron-methyl according to claim 2, characterized in that: In step S21, the pyrimidineamine solution is prepared by dissolving 35 g of pyrimidineamine in 100 g of dichloromethane.

4. A herbicidal composition containing mesosulfuron-methyl according to claim 1, characterized in that: The emulsifier is emulsifier 8801 produced by Nanjing Kehong Chemical Co., Ltd.

5. A herbicidal composition containing mesosulfuron-methyl according to claim 1, characterized in that: The safener is at least one of mefenpyr-butyl, ethyl 5-phenyl-4,5-dihydroisoxazole-3-carboxylate and 5-aminolevulinic acid.

6. A herbicidal composition containing mesosulfuron-methyl according to claim 5, characterized in that: The safener is prepared by mixing mefenpyr-butyl, 5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester and 5-aminolevulinic acid in a mass ratio of 3:4:

3.

7. A herbicidal composition containing mesosulfuron-methyl according to claim 1, characterized in that: The surfactant is prepared by mixing lauryl alcohol polyethylene glycol ether acetal, alkylphenol polyoxyethylene ether phosphate and alkyl polyoxyethylene ether sulfonate in a mass ratio of 5:4:

4.

8. The herbicidal composition containing mesosulfuron-methyl according to claim 1, characterized in that: The average particle size of the white carbon black is 5 microns, and the average particle size of the organic bentonite is 325 meshes.

9. A method for preparing a herbicidal composition containing mesosulfuron-methyl according to any one of claims 1 to 8, characterized in that: The following steps are involved: According to the dosage of the formula, mesosulfuron, emulsifier, safener, stabilizer, organic bentonite, white carbon black, surfactant and first-grade soybean salad oil are mixed and stirred evenly to obtain a herbicidal composition containing mesosulfuron.

10. Use of a herbicidal composition containing mesosulfuron-methyl as claimed in any one of claims 1 to 8 for controlling annual weeds in winter wheat fields, characterized in that: Use stem and leaf spray method, with a dosage of 60-100mL per acre.

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