Uniform stirring and mixing equipment for preparing urokinase

By combining stirring, jitter and filtration components in the urokinase preparation equipment, synchronous mixing and self-cleaning of urokinase raw materials and their auxiliary agents is achieved, solving the problem of low efficiency of existing equipment and improving mixing efficiency and purity.

CN119320691AInactive Publication Date: 2025-01-17山东康耐斯生物科技有限公司
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Patent Information

Application Number
CN202411878766.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-19
Publication Date
2025-01-17
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

Existing urokinase preparation equipment cannot achieve synchronous mixing, filtration and self-cleaning of urokinase raw materials and their auxiliary agents, resulting in low working efficiency.

Method used

A urokinase preparation device including a stirring tank, a jitter assembly and a filtration component is designed. The adhesion and agglomeration between the materials are broken through the coordination between the agitation component and the jitter assembly. The filter component lifts and lowers the impurities during stirring, and the scraping component automatically Clean up impurities to achieve uniform mixing of materials and guarantee purity.

Benefits of technology

The mixing efficiency of urokinase raw materials and their auxiliary agents is improved, the purity of the mixture is ensured, local overheating and filter plate blockage is avoided, and the continuous operation ability and working efficiency of the equipment is improved.

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Abstract

The invention discloses uniform stirring and mixing equipment for urokinase preparation, and particularly relates to the technical field of urokinase preparation equipment.The uniform stirring and mixing equipment comprises a stirring tank, a stirring assembly is arranged in the stirring tank, a shaking assembly is arranged at the upper end of the stirring tank, and filtering assemblies are symmetrically arranged on the two sides of the stirring tank. According to the stirring and uniform mixing equipment for preparing urokinase, the stirring assembly is matched with the shaking assembly, so that the stirring and uniform mixing equipment shakes up and down during rotation, the adhesion and agglomeration phenomena between urokinase raw materials and auxiliary agents thereof are broken, it is ensured that each part of materials can uniformly participate in the reaction, the problem of local overheating is avoided, and the service life of the urokinase raw materials is prolonged. The mixing efficiency is integrally improved, meanwhile, the filtering assembly can continuously ascend and descend during stirring, large-particle impurities or incompletely-dissolved solids in mixed liquid are captured and separated in real time, the purity of the mixed liquid is guaranteed, the mixed liquid is automatically cleaned through the scraping assembly, and continuous and effective work of the filtering assembly is guaranteed.
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Description

Technical Field

[0001] The invention relates to the technical field of urokinase preparation equipment, in particular to a stirring and uniform mixing equipment for urokinase preparation. Background Art

[0002] Urokinase is an enzyme protein isolated from healthy human urine or obtained from human kidney tissue culture. It can also be regarded as an enzyme substance secreted into the urine by the kidney and belongs to the protease family. Prourokinase is a precursor protein produced by the kidney. After partial degradation, it is excreted from the urine in the form of urokinase, or it can be extracted from kidney cell culture medium. In the production process of urokinase, stirring and mixing equipment plays a vital role.

[0003] Chinese patent announcement number CN220284061U discloses a stirring and mixing device for preparing urokinase, including a mixing chamber, a supporting foot is provided at the bottom of the mixing chamber, a feed port is embedded at the upper left end of the mixing chamber, a stirring chamber is provided in the middle of the mixing chamber, a filter chamber is provided at the upper left corner of the mixing chamber, the lower end of the feed port is connected to the top of the filter chamber, the lower right side of the filter chamber is connected to the left side wall of the stirring chamber through a conveying pipe, and a silica gel particle addition channel is provided at the upper right end of the mixing chamber. The utility model can filter out impurities in urine at multiple stages by providing a filter chamber, filter paper, filter net and activated carbon adsorption layer, thereby improving the quality of the prepared urokinase. In addition, by providing a silica gel particle addition channel, it is easy to add silica gel particles, and silica gel particles and urine can be input at the same time, thereby improving work efficiency. However, in the prior art, only the urokinase raw material and its auxiliary agent can be filtered individually, and it is impossible to achieve simultaneous mixing, filtering and self-cleaning, and the overall working efficiency is low. Summary of the invention

[0004] The main purpose of the present invention is to provide a stirring and mixing device for preparing urokinase, which can effectively solve the problem that urokinase raw materials and auxiliary agents cannot be mixed, filtered and self-cleaned synchronously.

[0005] To achieve the above object, the technical solution adopted by the present invention is: A stirring and mixing device for preparing urokinase comprises a stirring tank, a stirring component is arranged inside the stirring tank, a shaking component is arranged at the upper end of the stirring tank, filtering components are symmetrically arranged on both sides of the stirring tank, and two scraping components are arranged inside the stirring tank.

[0006] Preferably, a fixing plate is fixedly connected to the lower end of the stirring tank, a discharge port is fixedly connected to the lower end of the fixing plate, a supporting leg is fixedly connected to the lower end of the fixing plate, and a fixing seat is fixedly connected to the upper end of the stirring tank.

[0007] Preferably, the stirring assembly includes an L-shaped seat fixedly connected to the upper end of the stirring tank, a motor is fixedly installed on the upper end of the horizontal part of the L-shaped seat, a rotating shaft 1 is fixedly connected to the output end of the motor, a transmission mechanism 1 is fixedly connected to the outer surface of the rotating shaft 1, a rotating shaft 2 is fixedly connected to the inner surface of the transmission mechanism 1 away from the rotating shaft 1, and the rear side of the rotating shaft 2 is rotatably connected to the vertical part of the L-shaped seat.

[0008] Preferably, the front side of the rotating shaft 2 is fixedly connected with a bevel gear 1, the outer surface of the bevel gear 1 is meshingly connected with a bevel gear 2, the surface of the bevel gear 2 is fixedly connected with a rotating rod 1, the inner cavity of the rotating rod 1 is slidably connected with a rotating rod 2, the outer surface of the rotating rod 2 is rotatably connected to the stirring tank, the outer surface of the rotating rod 2 is fixedly connected with a limiting block 1, the outer surface of the limiting block 1 is slidably connected to the rotating rod 1, the front side of the vertical part of the L-shaped seat is fixedly connected with a support block, and the outer surface of the rotating rod 2 is fixedly connected to a stirring rod.

[0009] Preferably, the shaking assembly includes an eccentric wheel fixedly connected to an outer surface of a rotating shaft, the outer surface of the eccentric wheel is rotatably connected to a circular sleeve, the lower end of the circular sleeve is fixedly connected to a connecting rod, and the inner surface of the lower end of the connecting rod is rotatably connected to a fixed rod.

[0010] Preferably, the front side of the vertical part of the L-shaped seat is fixedly connected with a rotating shaft 2, the outer surface of the rotating shaft 2 is rotatably connected to two swing seats, the interiors of the two swing seats are slidably connected with sliding blocks, the outer surface of the rotating rod 2 is fixedly connected with a fixed block, the outer surface of the fixed block is symmetrically fixedly connected with a limiting axis, the ends of the two sliding blocks away from the swing seats are rotatably connected to the two limiting axes, and the outer surface of the fixed rod is fixedly connected to the two swing seats.

[0011] Preferably, the filter assembly includes a transmission mechanism 2 fixedly connected to the upper end of the rotating rod 1, a lower side of the transmission mechanism 2 away from the end of the rotating rod 1 is fixedly connected to a bidirectional screw rod, and an outer surface of the bidirectional screw rod is threadedly connected to a convex frame.

[0012] Preferably, the outer surface of the rotating rod 2 is fixedly connected to two limit blocks 2, the outer surface of the limit block 2 is slidably connected to a filter plate, the outer surface of the filter plate is provided with a through groove, the outer surface of the filter plate is provided with a limit groove 1, the outer surfaces of the two limit blocks 2 are slidably connected to the limit groove 1, and the outer surface of the filter plate is provided with a limit groove 2.

[0013] Preferably, one end of the convex frame away from the bidirectional screw rod is rotatably connected to the second limiting groove, and the side surface of the convex frame is rotatably connected to the inner surface of the mixing tank.

[0014] Preferably, the scraper assembly includes a spring fixedly connected to the top wall of the fixed seat, the bottom end of the spring is fixedly connected to a connecting plate, the internal thread of the connecting plate is connected to a bolt, the outer surface of the bolt is threadedly connected to a collecting box, and the lower end of the collecting box is slidably connected to the filter plate.

[0015] Compared with the prior art, the present invention has the following beneficial effects: The present invention cooperates with the stirring component and the shaking component to make them shake up and down synchronously when rotating, effectively breaking the adhesion and agglomeration between the urokinase raw material and its auxiliary agent, ensuring that each part of the material can evenly participate in the reaction, avoiding the problem of local overheating, and improving the overall mixing efficiency. At the same time, the filtering component will continue to rise and fall during stirring, capturing and separating large particles of impurities or incompletely dissolved solids in the mixed liquid in real time, ensuring the purity of the mixed liquid, and automatically cleaning it through the scraping component, ensuring the continuous and effective operation of the filtering component. The present invention achieves the effect of shaking the urokinase raw material and its auxiliary agents while stirring them through the coordination of the stirring component and the shaking component, so that the adhesion and agglomeration between the materials are effectively broken, the dispersion and mixing of the materials are promoted, and the urokinase raw material and its auxiliary agents can be more evenly distributed in the stirring tank. At the same time, the shaking component can also reduce the accumulation of materials on the stirring rod or the inner wall of the stirring tank, avoiding the problem of local overheating caused by excessive local materials. The present invention achieves the effect of real-time capture and separation of large particle impurities or incompletely dissolved solids in the mixed liquid by the structural coordination among the stirring component, the filtering component and the scraping component, thereby ensuring the purity of the mixed liquid. The scraping component can automatically clean the impurities on the filter plate, avoiding the downtime for cleaning caused by clogging of the filter plate, and improving the continuous operation capability and work efficiency of the equipment. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the overall structure of the present invention; Figure 2 It is a schematic diagram of the internal structure of the present invention; Figure 3 It is a schematic diagram of another state of the internal structure of the present invention; Figure 4 It is a partial structural schematic diagram of the stirring assembly of the present invention; Figure 5 It is a partial structural schematic diagram of the shaking component of the present invention; Figure 6 For the present invention Figure 5 A is an enlarged structural diagram; Figure 7It is a partial structural schematic diagram of the filter assembly of the present invention; Figure 8 For the present invention Figure 7 Schematic diagram of the structure at B in FIG. Fig. 9 It is a schematic diagram of the structure of the filter assembly of the present invention; Fig.10 It is a schematic structural diagram of the scraper assembly of the present invention.

[0017] In the figure: 1, mixing tank; 11, discharge port; 12, support leg; 13, fixed seat; 14, fixed plate; 2, mixing assembly; 21, L-shaped seat; 22, motor; 23, rotating shaft 1; 24, transmission mechanism 1; 25, bevel gear 1; 251, rotating shaft 2; 26, bevel gear 2; 27, rotating rod 1; 28, rotating rod 2; 29, limit block 1; 210, support block; 211, mixing rod; 3, shaking assembly; 31, eccentric wheel; 32, Circular ring sleeve; 33, connecting rod; 34, fixed rod; 35, rotating shaft 2; 36, swing seat; 37, sliding block; 38, fixed block; 39, limiting shaft; 4, filter assembly; 41, transmission mechanism 2; 42, two-way screw rod; 43, convex frame; 44, filter plate; 45, through groove; 451, limiting groove 1; 46, limiting block 2; 452, limiting groove 2; 5, scraper assembly; 51, spring; 52, connecting plate; 53, collecting box; 54, bolt. DETAILED DESCRIPTION

[0018] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further explained below in conjunction with specific implementation methods.

[0019] Embodiment 1, as Figure 1 As shown, a stirring and mixing device for preparing urokinase comprises a stirring tank 1, wherein a stirring component 2 is arranged inside the stirring tank 1, thereby ensuring the preliminary mixing of the urokinase raw material and its auxiliary agent in the container, and a shaking component 3 is arranged at the upper end of the stirring tank 1, thereby breaking the adhesion and agglomeration phenomenon between the materials, and the shaking can more effectively promote the dispersion and mixing of the materials, thereby ensuring that each part of the materials can evenly participate in the reaction, and filtering components 4 are symmetrically arranged on both sides of the stirring tank 1, thereby continuously filtering the urokinase raw material and its auxiliary agent while stirring, thereby capturing and separating large particle impurities or incompletely dissolved solids in the mixed liquid in real time during the stirring process, thereby avoiding the negative impact of these impurities on subsequent reactions or product quality, and two scraping components 5 are arranged inside the stirring tank 1, thereby avoiding the blockage problem caused by the accumulation of impurities, thereby ensuring the continuous and effective operation of the filtering component 4.

[0020] During the operation of this embodiment, the stirring component 2 and the shaking component 3 are coordinated to make them shake up and down synchronously during rotation, effectively breaking the adhesion and agglomeration between the urokinase raw material and its auxiliary agent, ensuring that each part of the material can participate in the reaction evenly, avoiding the problem of local overheating, and improving the overall mixing efficiency. At the same time, the filter component 4 will continue to rise and fall during stirring, capturing and separating large particles of impurities or incompletely dissolved solids in the mixed liquid in real time, ensuring the purity of the mixed liquid, and automatically cleaning it through the scraper component 5, ensuring the continuous and effective operation of the filter component 4.

[0021] Example 2: Based on Example 1, this example is to achieve the effect of shaking while stirring the urokinase raw material and its auxiliary agent. For details, see Figure 1-6 A fixing plate 14 is fixedly connected to the lower end of the mixing tank 1, a discharge port 11 is fixedly connected to the lower end of the fixing plate 14, a supporting leg 12 is fixedly connected to the lower end of the fixing plate 14, and a fixing seat 13 is fixedly connected to the upper end of the mixing tank 1. The fixing seat 13 is a semicircular opening, and materials can be loaded from the opening.

[0022] For further information, see Figure 3-5 The stirring assembly 2 includes an L-shaped seat 21 fixedly connected to the upper end of the stirring tank 1, a motor 22 is fixedly installed on the upper end of the horizontal part of the L-shaped seat 21, a rotating shaft 23 is fixedly connected to the output end of the motor 22, a transmission mechanism 24 is fixedly connected to the outer surface of the rotating shaft 23, the transmission mechanism 24 is composed of a belt and two pulleys, and belongs to the prior art, a rotating shaft 251 is fixedly connected to the inner surface of the transmission mechanism 24 away from the rotating shaft 23, and the rear side of the rotating shaft 251 is rotatably connected to the vertical part of the L-shaped seat 21.

[0023] For further information, see Figure 3 , Figure 5 and Figure 6The front side of the rotating shaft 251 is fixedly connected with a bevel gear 1 25, and the rotating shaft 251 can limit the transmission mechanism 1 24 and the bevel gear 1 25, and the outer surface of the bevel gear 1 25 is meshedly connected with a bevel gear 26, and the surface of the bevel gear 26 is fixedly connected with a rotating rod 1 27, and the bevel gear 26 can drive the rotating rod 1 27 to rotate, and the inner cavity of the rotating rod 1 27 is slidably connected with a rotating rod 28, and the outer surface of the rotating rod 28 is rotatably connected to the stirring tank 1, and the outer surface of the rotating rod 28 is fixedly connected with a limiting block 1 29, and the outer surface of the limiting block 1 29 is slidably connected to the rotating rod 1 27, and the limiting block 1 29 can make the rotating rod 28 rotate with the rotating rod 1 27, and at the same time does not hinder the up and down movement of the rotating rod 28, and the front side of the vertical part of the L-shaped seat 21 is fixedly connected with a supporting block 210, which is convenient for providing support for the rotating rod 1 27 and the rotating rod 28 to keep it stable, and the outer surface of the rotating rod 28 is fixedly connected with a stirring rod 211.

[0024] For further information, see Figure 5 The shaking assembly 3 includes an eccentric wheel 31 fixedly connected to the outer surface of the rotating shaft 23, the outer surface of the eccentric wheel 31 is rotatably connected to a ring sleeve 32, the lower end of the ring sleeve 32 is fixedly connected to a connecting rod 33, the rotation of the eccentric wheel 31 will drive the ring sleeve 32 and the connecting rod 33 to slightly shake up and down and left and right, the inner surface of the lower end of the connecting rod 33 is rotatably connected to a fixed rod 34, the fixed rod 34 can limit the ring sleeve 32 and the connecting rod 33, so that when it shakes up and down, it drives the two swing seats 36 to swing around the rotating shaft 2 35 as the axis.

[0025] For further information, see Figure 5-6 The front side of the vertical part of the L-shaped seat 21 is fixedly connected with a rotating shaft 25, and the outer surface of the rotating shaft 25 is rotatably connected to two swinging seats 36. The rotating shaft 25 is convenient for limiting the swinging seat 36, so that the swinging seat 36 can only swing with the rotating shaft 25 as the axis. The interior of the two swinging seats 36 is slidably connected with sliding blocks 37, and the outer surface of the rotating rod 28 is fixedly connected with a fixed block 38, and the outer surface of the fixed block 38 is symmetrically fixedly connected with the limiting axis 39. The two sliding blocks 37 are rotatably connected with the two limiting axes 39 at one end away from the swinging seat 36. When the swinging seat 36 drives the sliding block 37 to swing, it can drive the fixed block 38 and the rotating rod 28 as a whole to move slightly up and down, so that the entire stirring rod 211 will also continuously shake up and down when rotating, further breaking the adhesion and agglomeration phenomenon between the materials. The outer surface of the fixed rod 34 is fixedly connected to the two swinging seats 36, and the fixed rod 34 is convenient for connecting the connecting rod 33 with the swinging seat 36, so that the two move together.

[0026] Pour the urokinase raw material and its auxiliary agent into the stirring tank 1 from the opening of the fixed seat 13, start the motor 22 to drive the rotating shaft 23 to rotate, so that the rotating shaft 23 drives the transmission mechanism 24 to rotate, drives the bevel gear 1 25 to mesh with the bevel gear 26, drives the rotating rod 1 27 to rotate, and rotates the rotating rod 28, the limiting block 1 29 and the stirring rod 211 together to stir the urokinase raw material and its auxiliary agent, and the rotating shaft 1 23 will drive the eccentric wheel 31 to rotate while rotating, thereby driving the annular sleeve 32 and the connecting rod 33 to shake up and down and left and right, and further drive the swing seat 36 to swing up and down with the rotating shaft 2 35 as the axis, so that the sliding block 37, the fixed block 38 and the limiting shaft 39 drive the rotating rod 28 and the stirring rod 211 to shake up and down as a whole.

[0027] Therefore, the present scheme achieves the effect of shaking the urokinase raw material and its auxiliary agent while stirring through the cooperation of the stirring component 2 and the shaking component 3, so as to effectively break the adhesion and agglomeration between the materials, promote the dispersion and mixing of the materials, and make the urokinase raw material and its auxiliary agent more evenly distributed in the stirring tank 1. At the same time, the shaking component 3 can also reduce the accumulation of materials on the stirring rod 211 or the inner wall of the stirring tank 1, avoiding the problem of local overheating caused by excessive local materials.

[0028] Embodiment 3: This embodiment is based on Embodiments 1 and 2, and is for achieving the effect of continuous filtration and automatic cleaning of urokinase raw materials and auxiliary agents thereof.

[0029] For details, see Figure 1-3 , Figure 7-10 The filter assembly 4 includes a transmission mechanism 2 41 fixedly connected to the upper end of the rotating rod 1 27. The transmission mechanism 2 41 is composed of a belt and two pulleys, which is the prior art. The lower side of the transmission mechanism 2 41 away from one end of the rotating rod 1 27 is fixedly connected with a bidirectional screw rod 42. The outer surface of the bidirectional screw rod 42 is threadedly connected with a convex frame 43. The rotation of the bidirectional screw rod 42 can drive the convex frame 43 to continuously perform lifting and lowering movements on the surface of the bidirectional screw rod 42.

[0030] For further information, see Figure 2 , Figure 3 , Fig. 9 and Fig.10The outer surface of the rotating rod 28 is fixedly connected with two limit blocks 246, and the outer surface of the limit block 46 is slidably connected with the filter plate 44. The outer surface of the filter plate 44 is provided with a through groove 45, and the outer surface of the filter plate 44 is provided with a limit groove 1 451. The outer surfaces of the two limit blocks 46 are slidably connected with the limit groove 1 451. The limit block 46 can limit the filter plate 44 so that it rotates with the rotating rod 28, and can also be lifted and lowered on the limit block 46, and the position of the limit groove 2452 is always on the same vertical line with the stirring rod 211. The outer surface of the filter plate 44 is provided with a limit groove 2452, so that the filter plate 44 will not be blocked by the stirring rod 211 when it is lifted and lowered.

[0031] Furthermore, one end of the convex frame 43 away from the bidirectional screw rod 42 is rotatably connected to the second limiting groove 452, and the side surface of the convex frame 43 is rotatably connected to the inner surface of the stirring tank 1. The convex frame 43 can drive the filter plate 44 to rise and fall back and forth, allowing the filter plate 44 to repeatedly filter the urokinase raw material and its auxiliary agent to ensure their purity and stability, and the side surface of the convex frame 43 can also be used to clean the inner wall of the stirring tank 1 to avoid residues adhering to the inner wall.

[0032] For further information, see Fig.10 The scraper assembly 5 includes a spring 51 fixedly connected to the top wall of the fixing seat 13, which can provide a buffer space for the rise of the filter plate 44. When the filter plate 44 contacts the collecting box 53, it can still rotate and move upward a certain distance, so that the collecting box 53 can scrape away the impurities filtered out from the surface of the filter plate 44. The bottom end of the spring 51 is fixedly connected to a connecting plate 52, and the internal thread of the connecting plate 52 is connected to a bolt 54. The outer surface of the bolt 54 is threadedly connected to the collecting box 53, which is convenient for replacing and cleaning the collecting box 53. The lower end of the collecting box 53 is slidably connected to the filter plate 44.

[0033] When the rotating rod 1 27 is rotating, it can drive the two transmission mechanisms 2 41 to rotate, and the transmission mechanism 2 41 drives the two-way screw rods 42 on both sides to rotate in the same direction, so that the convex frame 43 drives the filter plate 44 to pass through the stirring rod 211, and continuously rise and fall inside the stirring tank 1. When the upper end of the filter plate 44 contacts the collecting box 53, it continues to rise and rotate. At this time, the upward force will squeeze the spring 51, so that the collecting box 53 and the filter plate 44 are more closely fitted. The collecting box 53 can clean the impurities filtered out on the surface of the filter plate 44 and collect them inside the collecting box 53. Then the filter plate 44 will continue to descend and rise with the convex frame 43, and continuously reciprocate to filter the urokinase raw material and its auxiliary agent. Among them, the collecting box 53 can be separated from the connecting plate 52 by the bolt 54, which is convenient for cleaning and replacing the collecting box 53.

[0034] Therefore, this solution uses the structural coordination between the stirring component 2, the filtering component 4 and the scraper component 5 to enable the filter plate 44 to continuously rise and fall during the stirring process, thereby achieving the effect of real-time capture and separation of large particles of impurities or incompletely dissolved solids in the mixed liquid, thereby ensuring the purity of the mixed liquid, while the scraper component 5 can automatically clean the impurities on the filter plate 44, avoiding the downtime for cleaning caused by blockage of the filter plate 44, thereby improving the continuous operation capability and work efficiency of the equipment.

[0035] It should be noted that the specific installation method, circuit connection method and control method of the motor 22, transmission mechanism 1 24 and transmission mechanism 2 41 used in the present invention are all conventional designs and will not be elaborated in detail in the present invention.

[0036] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A stirring and mixing device for preparing urokinase, comprising a stirring tank (1), characterized in that: The stirring tank (1) is provided with a stirring assembly (2) inside, a shaking assembly (3) is provided at the upper end of the stirring tank (1), filtering assemblies (4) are symmetrically provided on both sides of the stirring tank (1), and two scraping assemblies (5) are provided inside the stirring tank (1).

2. The stirring and mixing device for preparing urokinase according to claim 1, characterized in that: The lower end of the stirring tank (1) is fixedly connected to a fixing plate (14), the lower end of the fixing plate (14) is fixedly connected to a discharge port (11), the lower end of the fixing plate (14) is fixedly connected to a supporting leg (12), and the upper end of the stirring tank (1) is fixedly connected to a fixing seat (13).

3. A stirring and mixing device for preparing urokinase according to claim 2, characterized in that: The stirring assembly (2) comprises an L-shaped seat (21) fixedly connected to the upper end of the stirring tank (1); a motor (22) is fixedly mounted on the upper end of the horizontal portion of the L-shaped seat (21); a rotating shaft 1 (23) is fixedly connected to the output end of the motor (22); a transmission mechanism 1 (24) is fixedly connected to the outer surface of the rotating shaft 1 (23); a rotating shaft 2 (251) is fixedly connected to the inner surface of the transmission mechanism 1 (24) at an end away from the rotating shaft 1 (23); and a rear side of the rotating shaft 2 (251) is rotatably connected to the vertical portion of the L-shaped seat (21).

4. The stirring and mixing device for preparing urokinase according to claim 3, characterized in that: The front side of the second rotating shaft (251) is fixedly connected to a bevel gear (25), the outer surface of the bevel gear (25) is meshingly connected to a bevel gear (26), the surface of the bevel gear (26) is fixedly connected to a rotating rod (27), the inner cavity of the rotating rod (27) is slidably connected to a rotating rod (28), the outer surface of the rotating rod (28) is rotatably connected to the stirring tank (1), the outer surface of the rotating rod (28) is fixedly connected to a limiting block (29), the outer surface of the limiting block (29) is slidably connected to the rotating rod (27), the front side of the vertical part of the L-shaped seat (21) is fixedly connected to a support block (210), and the outer surface of the rotating rod (28) is fixedly connected to a stirring rod (211).

5. The stirring and mixing device for preparing urokinase according to claim 4, characterized in that: The shaking assembly (3) comprises an eccentric wheel (31) fixedly connected to the outer surface of the rotating shaft (23); the outer surface of the eccentric wheel (31) is rotatably connected to a circular ring sleeve (32); the lower end of the circular ring sleeve (32) is fixedly connected to a connecting rod (33); and the inner surface of the lower end of the connecting rod (33) is rotatably connected to a fixing rod (34).

6. The stirring and mixing device for preparing urokinase according to claim 5, characterized in that: The front side of the vertical part of the L-shaped seat (21) is fixedly connected to a second rotating shaft (35); the outer surface of the second rotating shaft (35) is rotatably connected to two swing seats (36); the interiors of the two swing seats (36) are slidably connected to sliding blocks (37); the outer surface of the second rotating rod (28) is fixedly connected to a fixed block (38); the outer surface of the fixed block (38) is symmetrically fixedly connected to a limit shaft (39); one end of the two sliding blocks (37) away from the swing seat (36) is rotatably connected to the two limit shafts (39); and the outer surface of the fixed rod (34) is fixedly connected to the two swing seats (36).

7. The stirring and mixing device for preparing urokinase according to claim 4, characterized in that: The filter assembly (4) comprises a second transmission mechanism (41) fixedly connected to the upper end of the first rotating rod (27); a bidirectional screw rod (42) is fixedly connected to the lower side of the second transmission mechanism (41) away from one end of the first rotating rod (27); and a convex bracket (43) is threadedly connected to the outer surface of the bidirectional screw rod (42).

8. The stirring and mixing device for preparing urokinase according to claim 7, characterized in that: The outer surface of the second rotating rod (28) is fixedly connected to two second limit blocks (46), the outer surface of the second limit block (46) is slidably connected to a filter plate (44), the outer surface of the filter plate (44) is provided with a through groove (45), the outer surface of the filter plate (44) is provided with a first limit groove (451), the outer surfaces of the two second limit blocks (46) are slidably connected to the first limit groove (451), and the outer surface of the filter plate (44) is provided with a second limit groove (452).

9. The stirring and mixing device for preparing urokinase according to claim 8, characterized in that: One end of the convex frame (43) away from the bidirectional screw rod (42) is rotatably connected to the second limiting groove (452), and the side surface of the convex frame (43) is rotatably connected to the inner surface of the stirring tank (1).

10. The stirring and mixing device for preparing urokinase according to claim 8, characterized in that: The scraper assembly (5) comprises a spring (51) fixedly connected to the top wall of the fixing seat (13); the bottom end of the spring (51) is fixedly connected to a connecting plate (52); the inner surface of the connecting plate (52) is threadedly connected to a bolt (54); the outer surface of the bolt (54) is threadedly connected to a collecting box (53); and the lower end of the collecting box (53) is slidably connected to the filter plate (44).

Citation Information

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