Exothermic external application preparation for treating shoulder, neck, waist and leg pain and preparation method thereof

Abstract

The invention discloses a fever external application preparation for treating shoulder, neck, waist and leg pain and a preparation method thereof. The fever external application preparation comprises safflower, pseudo-ginseng, ligusticum wallichii, frankincense, myrrh and dragon's blood. Folium artemisiae argyi, cassia twig, dried ginger, gentiana macrophylla and rhizoma drynariae; radix codonopsis, radix astragali, radix ginseng, radix rehmanniae praeparata, radix angelicae sinensis, rhizoma atractylodis macrocephalae, poria cocos and radix glycyrrhizae; the traditional Chinese medicine is prepared from radix clematidis, anisetree bark, lycopodium clavatum, notopterygium root, radix angelicae pubescentis, herba artemisiae anomalae, radix saposhnikoviae, turmeric and mustard. Various medicinal materials are compatible according to the theory of traditional Chinese medicine and can generate a synergistic effect. For example, the medicinal materials for promoting blood circulation to remove blood stasis are matched with the medicinal materials for warming and activating meridians, so that blood circulation is promoted to remove blood stasis on the basis of warming and activating meridians, blood stasis is easier to dissipate, and qi and blood circulation is smoother. The wind-dispelling and dampness-eliminating medicinal materials and the qi-tonifying and blood-nourishing medicinal materials are combined for use, so that the resistance of the body is enhanced while exogenous evil is eliminated, the evil is eliminated without hurting the body resistance, the body resistance is strengthened without leaving evil, and the effect of the whole preparation on treating the shoulder, neck, waist and leg pain is enhanced.

Description

Technical Field

[0001] The invention relates to a heating external compress preparation for treating pain in the shoulder, neck, waist and legs, and in particular to a heating external compress preparation for treating pain in the shoulder, neck, waist and legs and a preparation method thereof. Background Art

[0002] Shoulder, neck, waist and leg pain has become an extremely common disease in modern society, and its incidence rate is showing an upward trend. In the modern fast-paced life mode, people's lifestyles have undergone tremendous changes, which has largely led to the high incidence of shoulder, neck, waist and leg pain.

[0003] Modern office workers often work at their desks and sit for long periods of time. Coupled with aging, lack of attention to health, and external factors, they are prone to shoulder, neck, waist and leg pain. Pain not only affects the body, but can develop from mild soreness to severe tingling or distending pain, seriously affecting life, reducing quality of life and work efficiency, and even causing psychological problems. Treatment methods include oral medications, physical therapy, and surgical treatment. The effective amount of oral medications is reduced after the first-pass effect of the digestive system and liver, and it is also easy to cause gastrointestinal discomfort. Physical therapy requires regular visits to medical institutions, which is inconvenient, the effect is not lasting, and the cost is high. Surgical treatment has high risks, with risks of infection, bleeding, and nerve damage. The postoperative recovery period is long, the cost is high, and it is easy to relapse, and it also brings a psychological burden. Surgery is generally considered when the pain is severe and other methods are ineffective. Therefore, there is an urgent need for a better preparation for treating shoulder, neck, waist and leg pain on the market. Summary of the invention

[0004] The technical problem to be solved by the present invention is to overcome the defects of the above-mentioned technology and provide a heating external application preparation for treating shoulder, neck, waist and leg pain and a preparation method thereof.

[0005] In order to solve the above technical problems, the technical solution provided by the present invention is a heating external application preparation for treating shoulder, neck, waist and leg pain and a preparation method thereof, comprising:

[0006] 3-10g safflower, 3-9g Panax notoginseng, 3-10g Chuanxiong, 3-10g frankincense, 3-10g myrrh, 1-2g dragon's blood;

[0007] Artemisia argyi 3-10g, cinnamon twig 3-10g, dried ginger 3-10g, gentiana macrophylla 3-10g, drynariae rhizome 3-10g;

[0008] Codonopsis pilosula 9-30g, Astragalus membranaceus 9-30g, Ginseng 3-9g, Rehmannia root 9-15g, Angelica 6-12g, Atractylodes macrocephala 6-12g, Poria 9-15g, Licorice root 3-6g;

[0009] Clematis 6-10g, Radix Glehniae 3-6g, Herba Lycopodii 9-15g, Radix Notopterygii 3-10g, Radix Angelicae Pubescentis 3-10g, Radix Angelicae Pubescentis 6-10g, Radix Saposhnikoviae 3-10g, Rhizoma Curcumae 3-10g, Semen Sinapis 3-6g;

[0010] Pearl 3-6g, clove 1-3g, Eucommia ulmoides 6-10g, tangerine peel 3-10g, bupleurum 3-10g, scorpion 3-6g, vegetable oil 3-6g, propolis 3-6g, pine smoke toner 1-2g, camphor 1-2g, menthol 1-2g.

[0011] As an improvement, it includes: 3g of safflower, 3g of Panax notoginseng, 3g of Chuanxiong, 3g of frankincense, 3g of myrrh, and 1g of dragon's blood;

[0012] Artemisia argyi 3g, cinnamon twig 3g, dried ginger 3g, gentiana macrophylla 3g, drynariae rhizome 3g;

[0013] Codonopsis pilosula 9g, Astragalus membranaceus 9g, Ginseng 3g, Rehmannia glutinosa 9g, Angelica sinensis 6g, Atractylodes macrocephala 6g, Poria 9g, Licorice root 3g;

[0014] Clematis 6g, Radix Glehniae 3g, Herba Lycopodii 9g, Radix Notopterygii 3g, Radix Angelicae Pubescentis 3g, Radix Angelicae Pubescentis 6g, Radix Saposhnikoviae 3g, Rhizoma Curcumae 3g, Semen Sinapis 3g;

[0015] Pearl 3g, clove 1g, Eucommia ulmoides 6g, tangerine peel 3g, bupleurum 3g, scorpion 3g, vegetable oil 3g, propolis 3g, pine smoke toner 1g, camphor 1g, menthol 1g.

[0016] As an improvement, it includes: 10g of safflower, 9g of Panax notoginseng, 10g of Chuanxiong, 10g of frankincense, 10g of myrrh, and 2g of dragon's blood;

[0017] Artemisia argyi 10g, cinnamon twig 10g, dried ginger 10g, gentiana macrophylla 10g, drynariae rhizome 10g;

[0018] Codonopsis pilosula 30g, Astragalus membranaceus 30g, Ginseng 9g, Rehmannia root 15g, Angelica 12g, Atractylodes macrocephala 12g, Poria 15g, Licorice root 6g;

[0019] Clematis 10g, Radix Glehniae 6g, Herba Lycopodii 15g, Radix Notopterygii 10g, Radix Angelicae Pubescentis 10g, Radix Angelicae Pubescentis 10g, Radix Saposhnikoviae 10g, Rhizoma Curcumae 10g, Semen Sinapis 6g;

[0020] Pearl 6g, clove 3g, Eucommia ulmoides 10g, tangerine peel 10g, bupleurum 10g, scorpion 6g, vegetable oil 6g, propolis 6g, pine smoke ink powder 2g, camphor 2g, menthol 2g.

[0021] As an improvement, it includes: 6.5g safflower, 6g Panax notoginseng, 6.5g Chuanxiong, 6.5g frankincense, 6.5g myrrh, 1.5g Sanguisorba officinalis,

[0022] 6.5g of mugwort leaf, 6.5g of cinnamon twig, 6.5g of dried ginger, 6.5g of gentiana macrophylla, 6.5g of drynaria,

[0023] Codonopsis pilosula 19.5g, Astragalus membranaceus 19.5g, Ginseng 6g, Rehmannia glutinosa 12g, Angelica sinensis 9g, Atractylodes macrocephala 9g, Poria 12g, Licorice root 4.5g,

[0024] Clematis 8g, Radix Glehniae 4.5g, Herba Lycopodii 12g, Radix Notopterygii 6.5g, Radix Angelicae Pubescentis 6.5g, Radix Ligustici Nucifera 8g, Radix Saposhnikoviae 6.5g, Rhizoma Curcumae 6.5g, Semen Sinapis 4.5g,

[0025] Pearl 4.5g, clove 2g, Eucommia ulmoides 8g, tangerine peel 6.5g, bupleurum 6.5g, scorpion 4.5g, vegetable oil 4.5g, propolis 4.5g, pine smoke toner 1.5g, camphor 1.5g, menthol 1.5g.

[0026] The method includes the steps of weighing medicinal materials, crushing medicinal materials, preparing matrix, preparing preparations and packaging.

[0027] As an improvement, weigh the medicinal materials:

[0028] First, accurately weigh each medicinal ingredient according to the type of medicinal ingredient in the formula and the average weight required for each;

[0029] When weighing, use an accurate electronic scale to ensure that the weight of each medicinal ingredient meets the recipe requirements.

[0030] As an improvement, crush the herbs:

[0031] Place the weighed Chinese medicinal materials in a cool and ventilated place to dry naturally or use an oven to dry at low temperature to remove excess moisture and prevent the medicinal materials from deteriorating;

[0032] After drying, the medicinal materials are put into a Chinese medicine grinder for crushing;

[0033] Pearl treatment: Pearls need to be treated separately due to their hard texture;

[0034] Put it into a special pulverizing device to grind it into extremely fine powder, and screen it through a 80-100 mesh screen;

[0035] Grinding of other medicinal materials: Put the medicinal materials with lower hardness, such as mugwort leaves and cassia twigs, into the grinder and grind them. After grinding, pass them through a 60-80 mesh screen to ensure the fineness of the powder;

[0036] Finally, the pearl powder is mixed evenly with other medicinal material powders to obtain the final mixed medicinal powder for later use.

[0037] As an improvement, matrix preparation: select a container, pour 3-6g of vegetable oil into it, and use a heating device (such as a hot plate) to heat the vegetable oil to 60-80°C; at this temperature, the vegetable oil can better dissolve other ingredients;

[0038] Next, add 3-6g of propolis to the heated vegetable oil and continue stirring until the propolis is completely dissolved in the vegetable oil;

[0039] Subsequently, 1-2 g of pine smoke toner is added to the mixture and stirred evenly to ensure that the pine smoke toner is dispersed to form a stable matrix.

[0040] As an improvement, the preparation is as follows: the prepared mixed powder is slowly added to the prepared matrix, the stirring device is turned on, and the stirring speed is maintained between 200-300 rpm to ensure that the powder and the matrix are fully mixed to form a uniform drug paste;

[0041] When the temperature of the paste drops to 40-50°C, add 1-2g of camphor and 1-2g of menthol, and continue stirring until these two ingredients are completely dissolved in the paste.

[0042] As an improvement, packaging: the prepared herbal health cream is packaged into clean sealed bags or sealed containers according to the predetermined dosage;

[0043] Maintain a sterile environment during the packaging process to avoid contamination;

[0044] At the same time, the product name, production date, expiration date, usage, storage conditions and important information of precautions should be clearly marked on the packaging so that users can use it correctly.

[0045] The advantages of the present invention compared with the prior art are: promoting blood circulation and removing blood stasis, warming meridians and unblocking collaterals, and dispelling wind and dampness: the blood circulation and blood stasis-removing medicinal materials (such as safflower, Panax notoginseng, etc.), the meridian-warming and unblocking medicinal materials (such as wormwood, cassia twig, etc.) and the wind-removing and dampness-removing medicinal materials (such as clematis, lycopodiella clove, etc.) in the present preparation are mutually compatible, and comprehensive treatment is carried out for the various causes of shoulder, neck, waist and leg pain. From the perspective of traditional Chinese medicine, qi and blood stasis, cold stagnation of meridians, and rheumatism are the common causes of this type of pain. These medicinal materials are combined to remove pathological factors such as blood stasis, cold and dampness, and rheumatism (treating the symptoms), and can restore the normal physiological function of the body (treating the root cause) by regulating the operation of meridian qi and blood.

[0046] Invigorating Qi and nourishing blood, regulating internal organs: The Qi and blood nourishing herbs in the formula (such as Codonopsis pilosula, Astragalus membranaceus, etc.) help replenish the body's positive energy. In traditional Chinese medicine theory, sufficient positive energy can resist external pathogens and ensure smooth flow of Qi and blood. At the same time, some herbs, such as Eucommia ulmoides to nourish the liver and kidneys, and Tangerine peel to regulate Qi and strengthen the spleen, have a certain regulating effect on the functions of internal organs. When the liver and kidneys are replenished, the tendons and bones are nourished; when the spleen and stomach are healthy, the Qi and blood are active. This regulation of the functions of internal organs helps to fundamentally improve the pathogenesis of shoulder, neck, waist and leg pain.

[0047] Synergistic effect: Multiple herbs can be combined according to the theory of traditional Chinese medicine to produce synergistic effects. For example, herbs that promote blood circulation and dissipate blood stasis are combined with herbs that warm the meridians and dredge the collaterals. On the basis of warming and unblocking the meridians, herbs that promote blood circulation and dissipate blood stasis are combined, making blood stasis easier to dissipate and blood circulation smoother. Herbs that dispel wind and dampness are combined with herbs that replenish qi and nourish blood. While removing external evil, they enhance the body's resistance, so that evil is removed without hurting the body, and the body is strengthened without retaining evil, thereby enhancing the effect of the entire preparation in treating shoulder, neck, waist and leg pain. DETAILED DESCRIPTION

[0048] The present invention is further described in detail below with reference to specific embodiments.

[0049] A heating external application preparation for treating pain in the shoulder, neck, waist and legs and a preparation method thereof,

[0050] Embodiment 1:

[0051] 3-10g safflower, 3-9g Panax notoginseng, 3-10g Chuanxiong, 3-10g frankincense, 3-10g myrrh, 1-2g dragon's blood;

[0052] Artemisia argyi 3-10g, cinnamon twig 3-10g, dried ginger 3-10g, gentiana macrophylla 3-10g, drynariae rhizome 3-10g;

[0053] Codonopsis pilosula 9-30g, Astragalus membranaceus 9-30g, Ginseng 3-9g, Rehmannia root 9-15g, Angelica 6-12g, Atractylodes macrocephala 6-12g, Poria 9-15g, Licorice root 3-6g;

[0054] Clematis 6-10g, Radix Glehniae 3-6g, Herba Lycopodii 9-15g, Radix Notopterygii 3-10g, Radix Angelicae Pubescentis 3-10g, Radix Angelicae Pubescentis 6-10g, Radix Saposhnikoviae 3-10g, Rhizoma Curcumae 3-10g, Semen Sinapis 3-6g;

[0055] Pearl 3-6g, clove 1-3g, Eucommia ulmoides 6-10g, tangerine peel 3-10g, bupleurum 3-10g, scorpion 3-6g, vegetable oil 3-6g, propolis 3-6g, pine smoke toner 1-2g, camphor 1-2g, menthol 1-2g.

[0056] Weighing of medicinal materials:

[0057] First, accurately weigh each herb according to the type of herb in the formula and the average weight required for each. Use an accurate electronic scale to ensure that the weight of each herb meets the formula requirements. For example, 6.5g of safflower, 6g of Panax notoginseng, 6.5g of Chuanxiong, etc., until all the herbs are weighed.

[0058] Medicinal material crushing:

[0059] Place the weighed Chinese medicinal materials in a cool and ventilated place to dry naturally or use an oven at low temperature to remove excess moisture and prevent the medicinal materials from deteriorating. After drying, put the medicinal materials into a Chinese medicine grinder for crushing.

[0060] Pearl processing: Pearls need to be processed separately due to their hard texture. They are crushed into extremely fine powder in a special crushing equipment and screened through a 80-100 mesh screen.

[0061] Grinding of other medicinal materials: Put the medicinal materials with lower hardness such as mugwort leaves and cassia twigs into the grinder and grind them. After grinding, pass them through a 60-80 mesh sieve to ensure the fineness of the powder.

[0062] Finally, the pearl powder is mixed evenly with other medicinal material powders to obtain the final mixed medicinal powder for later use.

[0063] Matrix preparation:

[0064] Choose a container, pour 3-6g of vegetable oil into it, and use a heating device (such as a hot plate) to heat the vegetable oil to 60-80℃. At this temperature, the vegetable oil can better dissolve other ingredients. Next, add 3-6g of propolis to the heated vegetable oil and continue to stir until the propolis is completely dissolved in the vegetable oil. Then, add 1-2g of pine smoke toner powder to the mixture and continue to stir evenly to ensure that the pine smoke toner powder is dispersed and forms a stable matrix.

[0065] Preparation of formulations:

[0066] Slowly add the prepared mixed powder to the prepared matrix, turn on the stirring device, and keep the stirring speed between 200-300 rpm to ensure that the powder and the matrix are fully mixed to form a uniform paste. When the temperature of the paste drops to 40-50°C, add 1-2g camphor and 1-2g menthol, and continue stirring until these two ingredients are completely dissolved in the paste.

[0067] Packaging: Pack the prepared herbal health cream into clean sealed bags or sealed containers according to the predetermined dosage. Maintain a sterile environment during the packaging process to avoid contamination. At the same time, clearly mark the product name, production date, expiration date, usage, storage conditions and important information on the packaging to facilitate users to use it correctly.

[0068] Embodiment 2:

[0069] 3g safflower, 3g Panax notoginseng, 3g Chuanxiong, 3g frankincense, 3g myrrh, 1g Sanguisorba officinalis;

[0070] Artemisia argyi 3g, cinnamon twig 3g, dried ginger 3g, gentiana macrophylla 3g, drynariae rhizome 3g;

[0071] Codonopsis pilosula 9g, Astragalus membranaceus 9g, Ginseng 3g, Rehmannia glutinosa 9g, Angelica sinensis 6g, Atractylodes macrocephala 6g, Poria 9g, Licorice root 3g;

[0072] Clematis 6g, Radix Glehniae 3g, Herba Lycopodii 9g, Radix Notopterygii 3g, Radix Angelicae Pubescentis 3g, Radix Angelicae Pubescentis 6g, Radix Saposhnikoviae 3g, Rhizoma Curcumae 3g, Semen Sinapis 3g;

[0073] Pearl 3g, clove 1g, Eucommia ulmoides 6g, tangerine peel 3g, bupleurum 3g, scorpion 3g, vegetable oil 3g, propolis 3g, pine smoke toner 1g, camphor 1g, menthol 1g.

[0074] Embodiment three:

[0075] 10g safflower, 9g Panax notoginseng, 10g Chuanxiong, 10g frankincense, 10g myrrh, 2g Sanguisorba officinalis;

[0076] Artemisia argyi 10g, cinnamon twig 10g, dried ginger 10g, gentiana macrophylla 10g, drynariae rhizome 10g;

[0077] Codonopsis pilosula 30g, Astragalus membranaceus 30g, Ginseng 9g, Rehmannia root 15g, Angelica 12g, Atractylodes macrocephala 12g, Poria 15g, Licorice root 6g;

[0078] Clematis 10g, Radix Glehniae 6g, Herba Lycopodii 15g, Radix Notopterygii 10g, Radix Angelicae Pubescentis 10g, Radix Angelicae Pubescentis 10g, Radix Saposhnikoviae 10g, Rhizoma Curcumae 10g, Semen Sinapis 6g;

[0079] Pearl 6g, clove 3g, Eucommia ulmoides 10g, tangerine peel 10g, bupleurum 10g, scorpion 6g, vegetable oil 6g, propolis 6g, pine smoke ink powder 2g, camphor 2g, menthol 2g.

[0080] Embodiment 4:

[0081] 6.5g safflower, 6g Panax notoginseng, 6.5g Chuanxiong, 6.5g frankincense, 6.5g myrrh, 1.5g Sanguisorba officinalis,

[0082] 6.5g of mugwort leaf, 6.5g of cinnamon twig, 6.5g of dried ginger, 6.5g of gentiana macrophylla, 6.5g of drynaria,

[0083] Codonopsis pilosula 19.5g, Astragalus membranaceus 19.5g, Ginseng 6g, Rehmannia glutinosa 12g, Angelica sinensis 9g, Atractylodes macrocephala 9g, Poria 12g, Licorice root 4.5g,

[0084] Clematis 8g, Radix Glehniae 4.5g, Herba Lycopodii 12g, Radix Notopterygii 6.5g, Radix Angelicae Pubescentis 6.5g, Radix Ligustici Nucifera 8g, Radix Saposhnikoviae 6.5g, Rhizoma Curcumae 6.5g, Semen Sinapis 4.5g,

[0085] Pearl 4.5g, clove 2g, Eucommia ulmoides 8g, tangerine peel 6.5g, bupleurum 6.5g, scorpion 4.5g, vegetable oil 4.5g, propolis 4.5g, pine smoke toner 1.5g, camphor 1.5g, menthol 1.5g.

[0086] The effects, functions, pharmacological research and clinical application results of blood-activating and stasis-removing medicinal materials, including safflower, Panax notoginseng, Ligusticum chuanxiong, frankincense, myrrh and Sanguisorba officinalis.

[0087] Function and indications:

[0088] Improve blood circulation: In shoulder, neck, waist and leg pain, there is often poor blood circulation in some parts. For example, due to long-term poor posture, strain or trauma, blood stasis in these parts occurs. Blood-activating and stasis-removing herbs such as safflower, Panax notoginseng, Chuanxiong, frankincense, myrrh and dragon's blood can promote blood flow, eliminate blood stasis and make the meridians unobstructed, thereby relieving symptoms such as pain and swelling caused by blood circulation disorders.

[0089] For shoulder and neck pain, such as long-term desk work, the neck muscles are in a state of tension for a long time, which can easily cause blood stasis. These herbs can improve the blood supply to the neck and relieve pain. For waist and leg pain, such as congestion and swelling after a sprained waist or poor blood circulation in the legs caused by varicose veins, they can play a role in promoting blood circulation and removing blood stasis to relieve symptoms.

[0090] 1. Reduces Pain and Swelling:

[0091] This type of medicinal material has the effect of relieving pain and swelling. When the human body is injured or suffering from a disease, blood stasis will trigger a local inflammatory reaction, resulting in pain and swelling. Blood-activating and stasis-removing medicinal materials can relieve pain and swelling by improving the local circulation of qi and blood and reducing the accumulation of inflammatory mediators. For example, in the case of waist and leg pain caused by traumatic injuries, Panax notoginseng can both remove blood stasis and stop bleeding, and activate blood circulation and relieve pain, and has a significant effect on reducing pain and swelling in the injured area; frankincense and myrrh have similar effects, and they play an important role in reducing swelling and pain around joints.

[0092] Pharmacological studies:

[0093] Safflower: Safflower contains ingredients such as safflower yellow. Pharmacological studies have shown that safflower yellow has the effect of dilating blood vessels, increasing the inner diameter of blood vessels, reducing vascular resistance, and thus improving blood circulation. At the same time, it also has an antioxidant effect, which can reduce the damage of free radicals to vascular endothelial cells and protect the normal function of blood vessels, which helps to alleviate the pain in the shoulders, necks, waists and legs caused by vascular diseases.

[0094] Panax notoginseng: The main active ingredient of Panax notoginseng is Panax notoginseng saponin. Panax notoginseng saponin has the effect of inhibiting platelet aggregation and reducing blood viscosity, thereby preventing thrombosis and improving the rheological properties of blood. In addition, Panax notoginseng also has anti-inflammatory effects, which can inhibit the release of inflammatory factors and reduce inflammatory reactions, which is of great significance for relieving pain in the shoulder, neck, waist and legs caused by inflammation.

[0095] Chuanxiong: Chuanxiong is the main active ingredient in Chuanxiong. Chuanxiong can inhibit the contraction of vascular smooth muscle, dilate blood vessels, and increase local blood flow. At the same time, Chuanxiong also has the effects of anti-platelet aggregation and improving microcirculation, which helps to improve the nutrient supply of local tissues and promote the repair of damaged tissues, thereby alleviating pain in the shoulders, neck, waist and legs.

[0096] Frankincense and myrrh: Frankincense and myrrh contain volatile oils, resins and other ingredients. These ingredients have anti-inflammatory and analgesic effects. They can inhibit the activation of inflammatory cells and the release of inflammatory mediators, and reduce local inflammatory reactions. At the same time, they can also reduce pain perception by regulating the release of neurotransmitters, and have a positive effect on improving the symptoms of shoulder, neck, waist and leg pain.

[0097] Dragon's Blood: Dragon's Blood contains dracotin and other ingredients. Draconis has anti-coagulation, anti-inflammatory, and wound healing effects. In the treatment of shoulder, neck, waist and leg pain, its anti-coagulation effect helps to improve the hypercoagulable state of blood and prevent thrombosis; its anti-inflammatory effect can reduce local inflammatory reactions, promote the repair of painful areas, and relieve pain and swelling.

[0098] Clinical application effect:

[0099] Pain relief: In clinical applications, topical preparations containing these blood-activating and stasis-removing herbs have a significant pain-relieving effect on patients with shoulder, neck, waist and leg pain. After using them, many patients experienced a significant reduction in pain levels and a significant decrease in pain scores. For example, for patients with periarthritis of the shoulder, after using this topical preparation, shoulder pain was relieved in a short period of time and joint mobility was also improved. For waist and leg pain caused by lumbar disc herniation, long-term use of this preparation can also reduce the frequency and severity of pain attacks.

[0100] Swelling reduction: For local swelling caused by trauma or inflammation, such as swelling after ankle sprain or joint swelling caused by knee synovitis, the topical preparations made from these herbs can promote the reduction of swelling. Clinical observations have found that after using the preparations, the skin tension of the swollen area gradually decreases and the swelling range shrinks, which helps restore the normal function of the injured area.

[0101] Functional improvement: In patients with shoulder, neck, waist and leg pain, due to pain and swelling, they often suffer from functional disorders such as limited joint movement and decreased muscle strength. After using external application preparations containing blood-activating and blood-stasis-removing herbs, as pain and swelling are relieved, the patient's joint mobility gradually increases and muscle strength is also restored. For example, in patients with cervical spondylosis, the range of motion of the neck is improved after using the preparation, and they can turn their heads, lower their heads and raise their heads more freely; in patients with sciatica, the walking ability and muscle strength of the lower limbs are also improved to a certain extent.

[0102] The effects, functions and indications, pharmacological research and clinical application results of meridian-warming and collateral-unblocking medicinal materials, including mugwort leaf, cinnamon twig, dried ginger, gentiana macrophylla and drynaria.

[0103] Function and indications:

[0104] For the syndrome of cold stagnation in meridians: pain in the shoulder, neck, waist and legs is often related to poor blood circulation in the meridians. Stagnation of meridians by pathogenic cold is one of the common causes. This type of herbs can warm the meridians and dispel cold, and is suitable for pain caused by stagnation of blood and qi in the meridians due to invasion of pathogenic cold. For example, in the neck and shoulders, invasion of pathogenic cold may cause muscle tension and pain. Using these herbs can warm the local meridians and relieve pain; in the waist and legs, stagnation of pathogenic cold may cause cold pain and difficulty in movement. They can warm the meridians, dispel cold and relieve pain.

[0105] Improve blood circulation

[0106] Pain occurs when Qi and blood are blocked. Warming meridian and unblocking collaterals herbs can help to unblock Qi and blood blockages in the meridians. Whether it is Qi and blood stagnation caused directly by cold evil, or other factors leading to poor Qi and blood circulation and secondary cold stagnation, these herbs can promote the normal circulation of Qi and blood. For example, Drynaria fortunei has a certain effect on improving waist and leg pain caused by poor Qi and blood flow and meridian blockage due to trauma or liver and kidney deficiency; Gentiana macrophylla can be used to eliminate shoulder, neck, waist and leg pain caused by poor meridian flow caused by rheumatism.

[0107] Pharmacological studies:

[0108] Mugwort: The volatile oil components in mugwort have a warming and stimulating effect. Pharmacological studies have shown that mugwort volatile oil can dilate local blood vessels, improve blood circulation, and produce a local sense of warmth, thereby playing the role of warming the meridians and dispersing cold. At the same time, mugwort also has antibacterial and anti-inflammatory effects, which helps to reduce the local inflammatory response caused by cold stagnation of qi and blood.

[0109] Cinnamon twig: Cinnamon twig contains active ingredients such as cinnamaldehyde. Cinnamaldehyde has the effect of promoting blood circulation, dilating blood vessels, and enhancing blood flow, thereby achieving the effect of warming and unblocking the meridians. In addition, cinnamaldehyde also has certain anti-inflammatory and analgesic effects, which can reduce pain and inflammation caused by blocked meridians.

[0110] Dried ginger: The gingerol components in dried ginger have warming properties. These components can stimulate nerve endings, produce a warming sensation, and play a role in warming the meridians. At the same time, gingerol has anti-inflammatory and antioxidant effects, which can reduce the local inflammatory response caused by the cold pathogen stagnation of the meridians, improve the local microenvironment, and promote the smooth flow of qi and blood.

[0111] Gentiana macrophylla: Gentiana macrophylla mainly contains alkaloids such as genuine A and B. Genuine A has anti-inflammatory, analgesic and antipyretic pharmacological effects. In terms of warming the meridians and dredging the collaterals, genuine A can reduce local inflammatory reactions and regulate the body's immune function, thereby improving the conditions of meridian obstruction and poor blood circulation caused by rheumatism and other factors, achieving the purpose of dredging the meridians and relieving pain.

[0112] Drynaria: Drynaria contains ingredients such as naringin and drynaria dihydroflavonoids. Naringin has the effect of promoting bone formation and improving bone density, and has a certain improvement effect on waist and leg pain caused by liver and kidney deficiency, osteoporosis, etc. Drynaria dihydroflavonoids have anti-inflammatory and analgesic pharmacological properties, which helps to relieve local pain, and at the same time can promote local blood circulation, achieve the functions of warming the meridians and relieving pain.

[0113] Clinical application effect:

[0114] Relieve pain symptoms: In clinical applications, external application preparations made from these meridian-warming and collateral-dredging herbs have a significant effect on relieving pain in patients with shoulder, neck, waist and leg pain. For pain caused by cold pathogens, such as neck and shoulder pain caused by cold stagnation and qi stagnation, the pain level is significantly reduced after use. Among patients with waist and leg pain, especially those whose pain is aggravated by cold and relieved by warmth, the frequency and intensity of pain attacks are reduced after using this preparation.

[0115] Improve local cold sensation: For patients with local cold sensation, such as cold pain in the waist and feeling cold, the cold sensation will gradually decrease after using this external compress preparation. This is because the warming and cold-dispersing effects of these medicinal materials improve local blood circulation, and heat can be better transferred to local tissues, thereby improving the local cold symptoms.

[0116] Promoting joint mobility: In patients with shoulder, neck, waist and leg pain accompanied by limited joint mobility, the range of motion of the joints will be improved after using external compresses containing meridian-warming and collateral-dredging herbs. For example, in patients with frozen shoulder, the range of motion of the shoulder may be limited due to muscle tension and pain caused by cold stagnation in the meridians. After using this preparation, as the meridians are unblocked and the cold evil is dispelled, shoulder abduction, lifting and other activities gradually become more flexible. In patients with knee pain and poor flexion and extension, the flexion and extension function of the knee joint can also be improved to a certain extent after use.

[0117] The effects, functions, pharmacological research and clinical application results of Qi-tonifying and blood-nourishing herbs, including Codonopsis pilosula, Astragalus membranaceus, Ginseng, Rehmannia root, Angelica sinensis, Atractylodes macrocephala, Poria cocos and Licorice.

[0118] Function and indications:

[0119] Warming the meridians and dispersing cold: Among the causes of shoulder, neck, waist and leg pain, invasion of cold evil is one of the common factors. Cold is a yin evil that can easily damage yang energy. Coldness is stagnant and can cause poor circulation of qi and blood. Warming meridians and unblocking collaterals herbs such as wormwood leaf, cinnamon twig, dried ginger, gentiana macrophylla, and bone-healing stalk can warm and dissipate cold evil in the body.

[0120] For example, for neck and shoulder pain caused by prolonged exposure to cold, these herbs can warm the local meridians, dispel the evil cold, restore the warming effect of Yang Qi, and improve the circulation of Qi and blood. In the waist and legs, the invasion of evil cold may cause cold and dampness pain, and these herbs can specifically warm the cold and dampness and relieve pain.

[0121] Unblocking meridians and relieving pain

[0122] When cold pathogens stagnate the meridians or qi and blood deficiency causes meridian blockage, pain will occur. These herbs have the function of unblocking the meridians, which can clear the blockages in the meridians and make qi and blood flow smoothly, thus achieving the purpose of pain relief.

[0123] For example, Drynaria fortunei can be used to treat low back and leg pain caused by insufficient kidney qi and malnutrition of meridians, and it improves symptoms by tonifying the kidneys and strengthening bones, unblocking meridians and relieving pain; Gentiana macrophylla can eliminate rheumatism and unblock meridians, and has a good effect on relieving shoulder, neck, waist and leg pain caused by rheumatism blocking the meridians.

[0124] Pharmacological studies:

[0125] Mugwort: Mugwort mainly contains volatile oils, flavonoids and other ingredients. The ingredients in its volatile oils, such as eucalyptol, have antibacterial and anti-inflammatory effects, and can reduce local inflammatory reactions. From the perspective of warming the meridians and dispersing cold, volatile oil from mugwort can dilate local blood vessels, promote blood circulation, and make the body feel warm, thereby playing a role in warming the meridians.

[0126] Cinnamon twig: Cinnamon twig contains volatile oil, cinnamaldehyde and other ingredients. Cinnamaldehyde has antipyretic, analgesic and anti-inflammatory effects. Pharmacological studies have shown that cinnamon twig can dilate blood vessels and increase blood circulation. Its effect of warming and unblocking meridians may be related to its regulation of vasoconstriction. It can promote the circulation of the body's yang energy, dispel pathogenic cold, and improve the condition of cold stagnation in the meridians.

[0127] Dried ginger: Gingerol, the main ingredient in dried ginger, has anti-inflammatory, antioxidant, and antipyretic effects. Gingerol can stimulate vasodilation and improve local blood circulation. At the same time, its warming properties help dispel cold pathogens. In the treatment of shoulder, neck, waist and leg pain, dried ginger warms the meridians and alleviates the stagnation of qi and blood caused by cold pathogens.

[0128] Gentiana macrophylla: Gentiana macrophylla contains alkaloids such as genuine A and B. Genuine A has anti-inflammatory, analgesic and antipyretic effects. Genuine A can inhibit the release of inflammatory mediators and reduce local inflammatory reactions. At the same time, Gentiana macrophylla regulates the neuro-endocrine-immune network and improves the body's internal environment, thereby playing a role in removing rheumatism, unblocking meridians and relieving pain.

[0129] Drynaria: Drynaria contains ingredients such as naringin and drynaria dihydroflavonoids. These ingredients have the effects of promoting bone formation, improving bone density, anti-inflammatory, and analgesic. Drynaria dihydroflavonoids can regulate the activity of osteoblasts and osteoclasts, and play a role in treating waist and leg pain caused by osteoporosis or traumatic injuries by strengthening the kidneys and bones, unblocking meridians, and relieving pain.

[0130] Clinical application effect:

[0131] Pain relief: In clinical applications, topical preparations containing these meridian-warming and collateral-dredging herbs have a significant pain relief effect on patients with shoulder, neck, waist and leg pain. For patients with cold pain, such as patients with frozen shoulder syndrome (periarthritis of the shoulder), the shoulder pain is significantly relieved after using this preparation, especially in cold weather or at night. For patients with cold pain in the waist, such as patients with kidney-yang deficiency-type waist pain, the pain intensity and frequency of the waist are reduced after using this preparation.

[0132] Improvement of cold symptoms: It has a significant effect on improving the symptoms of cold symptoms caused by the invasion of cold evil, such as local chills and fear of wind. For example, some patients with neck and shoulder pain often have symptoms of fear of wind in the neck. After using this external application preparation, the fear of wind in the neck is significantly alleviated, and the local cold feeling gradually disappears.

[0133] Improved joint mobility: For patients with shoulder, neck, waist and leg pain accompanied by limited mobility, the cold pathogen stagnates the meridians, leading to poor joint mobility. After using external compresses containing meridian-warming and collateral-dredging herbs, the joint mobility gradually increases as the meridians are unblocked and the cold pathogen is dispelled. For example, for patients with knee pain accompanied by poor flexion and extension, the flexion and extension function of the knee joint is improved and the range of motion is expanded after using the preparation for a period of time.

[0134] The effects, main functions, pharmacological research and clinical application effects of medicinal materials for dispelling wind and dampness, such as Clematis chinensis, Radix Glehniae, Herba Lycopodii, Rhizoma Angelicae Pubescentis, Radix Angelicae Pubescentis, Rhizoma Ligustici Urtusa, Saposhnikovia divaricata, Curcuma longa and Semen Sinapis.

[0135] Function and indications:

[0136] Dispelling wind and dampness: In the pathogenesis of shoulder, neck, waist and leg pain, the invasion of wind evil and dampness evil is a common factor. Wind is the root of all diseases, and wind evil often coexists with dampness evil. These herbs for dispelling wind and dampness can dispel the wind evil and dampness evil that invade the shoulder, neck, waist and legs of the human body.

[0137] For example, for the waist and leg pain that is prone to occur when living in a humid environment or in humid weather, herbs such as Smilax glabra and Radix Glehniae can eliminate dampness in the body and improve symptoms such as heaviness and soreness caused by dampness blocking the meridians; for the neck and shoulder pain that occurs after exogenous wind evil, herbs such as Saposhnikovia divaricata and Notopterygium wilfordii can dispel wind evil and relieve muscle spasms and pain.

[0138] Unblocking meridians and relieving pain: When wind and dampness invade the human body, they often block the meridians, causing poor circulation of qi and blood, thus causing pain. Herbs that dispel wind and dampness have the effect of unblocking meridians, which can dredge the meridians blocked by wind and dampness, allowing qi and blood to flow smoothly, thereby achieving the purpose of relieving pain.

[0139] For example, herb Stretching Grass can stretch the tendons and veins, and has a very good effect on improving symptoms such as difficulty in flexing and extending the limb joints and pain caused by rheumatism blocking the meridians; Turmeric can break up blood and promote qi circulation, unblock menstruation and relieve pain, and can reduce pain in the shoulders, neck, waist and legs caused by blocked meridians.

[0140] Pharmacological studies:

[0141] Clematis: Clematis contains ingredients such as anemonin and proanemonin. Pharmacological studies have shown that these ingredients have anti-inflammatory and analgesic effects. Clematis can reduce inflammatory reactions, inhibit the release of pain mediators, and relax smooth muscles. It has a certain effect on relieving muscle tension and joint pain caused by rheumatism.

[0142] Maple bark: The volatile oil and other ingredients in the maple bark have anti-inflammatory, analgesic and anti-rheumatic effects. Its volatile oil components can regulate the body's immune function, reduce local inflammatory reactions, and inhibit the damage of rheumatic factors to joints and muscles, thereby playing a role in treating rheumatic pain.

[0143] Herba Lycopodiellae: Herba Lycopodiellae contains alkaloids such as lycopodiolae and lycopodiolae. These alkaloids have obvious analgesic and anti-inflammatory effects, and can inhibit the activation of inflammatory cells and the release of inflammatory mediators. Herba Lycopodiellae can also regulate the central nervous system and improve local blood circulation, thereby achieving the effect of dredging meridians and relieving pain.

[0144] Qianghuo: Qianghuo contains volatile oil, Qianghuo alcohol and other ingredients. Qianghuo alcohol has anti-inflammatory, antipyretic and analgesic effects. Its volatile oil can dilate cerebral and peripheral blood vessels, improve local blood circulation, relieve symptoms such as muscle soreness and joint pain caused by rheumatism and cold evil, and at the same time improve the body's ability to resist cold.

[0145] Duhuo: Duhuo contains dihydroanacardiaceae alcohol, angelica alcohol and other ingredients. These ingredients have anti-inflammatory, analgesic and sedative effects. Duhuo can regulate the central nervous system and relieve pain. At the same time, its anti-inflammatory effect can reduce local inflammatory reactions and is effective in treating rheumatic pain in the lower body.

[0146] Northern Liujinu: Northern Liujinu contains flavonoids, coumarins and other ingredients. Flavonoids have antioxidant and anti-inflammatory effects, and coumarins have blood circulation and analgesic effects. Northern Liujinu can reduce local inflammatory reactions, improve blood circulation, and have a certain therapeutic effect on shoulder, neck, waist and leg pain caused by blood stasis or rheumatic pain.

[0147] Saposhnikovia divaricata: Saposhnikovia divaricata contains volatile oils, chromones and other ingredients. Volatile oils have anti-inflammatory and analgesic effects, and chromones have antipyretic and anti-allergic effects. Saposhnikovia divaricata can reduce local inflammatory reactions, inhibit the occurrence of pain, and at the same time dispel wind evil and prevent it from invading the human body again.

[0148] Turmeric: Turmeric contains ingredients such as curcumin. Curcumin has multiple pharmacological effects such as anti-inflammatory, antioxidant, and anti-tumor. In the treatment of shoulder, neck, waist, and leg pain, curcumin can reduce local inflammatory reactions and improve pain symptoms by regulating cell signaling pathways. At the same time, its blood-breaking and qi-promoting effects help to dredge the meridians.

[0149] Mustard: Mustard contains glucosinolate, potassium glucosinolate and other ingredients. The isothiocyanates produced by enzymatic hydrolysis of glucosinolate have anti-inflammatory, analgesic and antibacterial effects. Mustard can promote local blood circulation and relieve pain and swelling caused by rheumatism blocking the meridians.

[0150] Clinical application effect:

[0151] Pain relief: In clinical applications, topical preparations containing these wind-removing and dampness-removing herbs have a significant pain relief effect on patients with shoulder, neck, waist and leg pain. For joint pain caused by rheumatoid arthritis, such as knee and shoulder joint pain, the pain level is significantly reduced after using this preparation, and the pain score is significantly reduced. For patients with waist and leg pain caused by exogenous wind and rheumatism, the frequency of pain attacks is also reduced.

[0152] Improved joint mobility: In patients with shoulder, neck, waist and leg pain accompanied by limited joint mobility, wind and dampness blocking the meridians lead to joint stiffness and difficulty in flexion and extension. After using external application preparations containing wind-removing and dampness-removing herbs, the range of motion of the joints gradually increases as the wind and dampness are removed and the meridians are unblocked. For example, in patients with frozen shoulder, the range of motion of the shoulder, such as abduction and lifting, is improved after using the preparation; in patients with rheumatoid arthritis, the flexibility of the joints, such as fingers and wrists, is also improved.

[0153] Prevent recurrence: This type of medicinal material can relieve pain and improve joint mobility. Due to its function of dispelling wind and dampness, it can also prevent wind and dampness from invading the human body again to a certain extent, thereby reducing the recurrence rate of shoulder, neck, waist and leg pain. For example, for patients with a history of rheumatic arthralgia, continuing to use the topical preparation for a period of time after the pain symptoms are relieved can reduce the possibility of pain recurrence caused by factors such as weather changes or fatigue.

[0154] Other medicinal materials and auxiliary materials, the effects, functions and indications, pharmacological research and clinical application effects of pearl, clove, eucommia bark, tangerine peel, bupleurum, scorpion, vegetable oil, propolis, pine smoke powder, camphor and menthol.

[0155] Function and indications:

[0156] Pearl: Pearl has the function of detoxification and muscle regeneration. In the treatment of shoulder, neck, waist and leg pain, if the local skin is damaged due to pain, friction or other reasons, pearls can help promote wound healing, prevent infection, reduce inflammatory reactions, and have a certain effect on improving the health of the local skin.

[0157] Clove: Clove warms the middle and lowers adverse reactions, nourishes the kidney and boosts yang. In this preparation, the warming effect of clove can assist in warming the meridians and dispersing cold, and has a certain effect on relieving pain in the shoulders, neck, waist and legs caused by cold stagnation in the meridians. It is especially suitable for pain accompanied by local chills, preference for warmth and other cold symptoms.

[0158] Eucommia: Eucommia nourishes the liver and kidneys and strengthens the tendons and bones. In the symptoms of shoulder, neck, waist and leg pain, it has an improving effect on tendon and bone weakness, waist and knee pain caused by liver and kidney deficiency. By nourishing the liver and kidneys, it strengthens the function of bones and muscles, thereby relieving pain and improving the movement ability of the limbs.

[0159] Tangerine peel: Tangerine peel can regulate qi and strengthen the spleen, and eliminate dampness and resolve phlegm. In preparations, the qi-regulating effect of tangerine peel helps regulate the circulation of qi and blood, allowing other drugs to better play their roles in promoting blood circulation and removing blood stasis, dispelling wind and removing dampness. Tangerine peel can play an auxiliary role in regulating local pain caused by qi stagnation or pain in the shoulders, neck, waist and legs caused by poor qi and blood circulation.

[0160] Bupleurum: Bupleurum can relieve fever, soothe the liver and relieve depression, and raise Yang Qi. In the treatment of shoulder, neck, waist and leg pain, Bupleurum can regulate the body's Qi and make Qi and blood flow smoothly, which helps to relieve pain caused by Qi stagnation or Yang Qi failure, especially for pain accompanied by depression or physical drowsiness.

[0161] Scorpion: Scorpion can calm wind and calm spasms, dredge meridians and relieve pain, and attack toxins and disperse nodules. In the preparation, the dredge meridian and relieve pain effect of the scorpion can directly act on the meridians of the shoulder, neck, waist and legs. It has a better effect on the situation of stubborn pain and severe meridian blockage, and can reduce the degree of pain.

[0162] Plant oil (excipient): Plant oil, as a matrix, moisturizes the skin, allowing the drug to better adhere to the skin surface and facilitate drug absorption. At the same time, it can prevent the drug from drying too quickly, prolong the contact time between the drug and the skin, and help the drug to play a therapeutic role.

[0163] Propolis (auxiliary material): Propolis has antibacterial and anti-inflammatory effects. In this topical preparation, propolis can prevent infection at the application site due to skin damage or inflammation, ensure the safety of the treatment process, and also help reduce local inflammatory reactions and promote pain relief.

[0164] Pine smoke toner (excipient): Pine smoke toner may have astringent and detumescent effects. In topical preparations, it can help reduce local swelling symptoms, promote astringency of painful areas, and improve local discomfort.

[0165] Camphor (auxiliary material): Camphor has the effects of reducing swelling and relieving pain, opening the meridians, and relieving stagnant qi. In the preparation, the cooling sensation produced by camphor not only increases the comfort of patients when using it, but also relieves local pain and inflammation and improves the condition of local qi and blood stagnation.

[0166] Menthol (auxiliary material): Menthol has the effects of dispelling wind, clearing heat and detoxifying. In the preparation, the cool feeling brought by menthol can relieve local pain and inflammation, and has a certain effect on relieving pain in the shoulder, neck, waist and legs caused by wind-heat or damp-heat, and can also make patients feel more refreshed and comfortable when using it.

[0167] Pharmacological studies:

[0168] Pearl: Pearl contains calcium carbonate, multiple amino acids and trace elements. Calcium carbonate is the main component of pearls, which helps promote tissue repair and wound healing. Amino acids and trace elements have anti-inflammatory and antioxidant effects, which can reduce local inflammatory reactions and promote cell regeneration and repair.

[0169] Clove: Clove mainly contains volatile oil, of which eugenol is the main active ingredient. Eugenol has anti-inflammatory, antibacterial, and analgesic pharmacological effects. It can inhibit the release of inflammatory factors, reduce local inflammatory reactions, and reduce pain perception by acting on nerve endings.

[0170] Eucommia: Eucommia contains ingredients such as eucommia gum and pinoresinol diglucoside. Pinoresinol diglucoside has the effect of promoting the proliferation and differentiation of osteoblasts, thus helping to strengthen bones. Eucommia gum and other ingredients have the effects of regulating the body's immune function and anti-inflammatory, and have a certain pharmacological basis for improving pain and decreased body function caused by liver and kidney deficiency.

[0171] Tangerine peel: Tangerine peel contains volatile oil, hesperidin and other ingredients. Hesperidin has anti-inflammatory, antioxidant, anti-allergic and other effects. Volatile oil components can regulate the movement of gastrointestinal smooth muscles, regulate the body's qi and blood circulation as a whole, alleviate local qi stagnation symptoms, and reduce inflammatory reactions.

[0172] Bupleurum:

[0173] Bupleurum contains ingredients such as saikosaponins. Saikosaponins have anti-inflammatory, antipyretic, and immune-regulating effects. They can inhibit the release of inflammatory mediators, regulate the body's immune response, thereby smoothing the flow of qi and blood and alleviating pain in the shoulders, necks, waists, and legs caused by inflammation or immune disorders.

[0174] Scorpion: Scorpion contains scorpion toxin and other ingredients. Scorpion toxin has analgesic, anti-inflammatory, anticonvulsant and other effects. It can reduce pain perception by regulating the release of neurotransmitters, inhibiting the activation of inflammatory cells and the release of inflammatory mediators, thereby reducing local pain and inflammation.

[0175] Propolis: Propolis contains a variety of compounds such as flavonoids and terpenes. Flavonoids have antibacterial, anti-inflammatory, and antioxidant effects, and terpenes have immunomodulatory effects. These ingredients work together to make propolis have the effects of antibacterial, anti-inflammatory, and enhancing immunity, and play an important auxiliary therapeutic role in topical preparations.

[0176] Pine soot toner: The pharmacological mechanism of pine soot toner is not very clear, but it may be related to the carbon and other ingredients it contains. Carbon has a certain adsorption and astringent effect, which may help reduce local swelling and exudation, thereby playing a role in astringency and swelling reduction.

[0177] Camphor: Camphor stimulates the cold receptors on the skin, causing local vascular reflex dilation and improving local blood circulation. At the same time, camphor also has certain anti-inflammatory and analgesic effects, which can reduce local pain and inflammatory reactions.

[0178] Menthol: Menthol can stimulate the cold receptors at the nerve endings, producing a cooling sensation. Pharmacologically, menthol has anti-inflammatory, analgesic, and antipruritic effects, and can reduce local inflammatory reactions and relieve pain symptoms.

[0179] Clinical application effect:

[0180] Pain relief: In clinical applications, topical preparations containing these herbs and excipients have a significant pain relief effect on patients with shoulder, neck, waist and leg pain. Herbs such as scorpion, clove, and bupleurum can relieve pain through their respective pharmacological effects. Whether it is pain caused by qi stagnation and blood stasis, cold stagnation in the meridians or other reasons, it can be relieved to a certain extent. The cooling sensation brought by camphor and menthol can also help distract patients from the pain and further reduce the subjective feeling of pain.

[0181] Improvement of local symptoms: Pearls can help repair local skin and improve skin conditions for patients with damaged or inflamed skin. The antibacterial and anti-inflammatory effects of propolis can prevent skin infection and have a good improvement effect on patients with inflammatory symptoms such as redness, swelling, heat and pain in the painful area. The astringent effect of pine soot toner can reduce local swelling and improve the appearance and discomfort of the painful area.

[0182] Overall function regulation: Eucommia ulmoides nourishes the liver and kidneys, and tangerine peel regulates qi and strengthens the spleen, which helps regulate the body's functions as a whole. For shoulder, neck, waist and leg pain caused by liver and kidney deficiency or poor blood circulation, while relieving pain, it can also improve the body's resistance and self-repair ability. Bupleurum's role in regulating qi and other functions also helps improve the patient's overall physical condition and reduce the recurrence rate of pain. Vegetable oil as a matrix ensures the effective application of the drug, allowing other medicinal materials and excipients to play a better role and jointly improve the symptoms of shoulder, neck, waist and leg pain.

[0183] 1. Medicinal materials for promoting blood circulation and removing blood stasis:

[0184] Safflower: Effect: Safflower has the effects of promoting blood circulation, dredge meridians, dissipate blood stasis and relieve pain. In the treatment of shoulder, neck, waist and leg pain, it helps to improve local blood circulation, eliminate pain and swelling caused by blood stasis, promote the dissipation of blood stasis, and make the meridians unobstructed.

[0185] Panax notoginseng: Function: Panax notoginseng is a well-known hemostatic and stasis-removing medicine, and also has the effect of reducing swelling and relieving pain. In external application preparations, Panax notoginseng can be used to remove blood stasis and stop bleeding, promote blood circulation and relieve pain for local blood stasis caused by trauma or poor blood circulation, help relieve blood stasis and swelling in the painful area, and promote tissue repair.

[0186] Chuanxiong: Effect: Chuanxiong is a blood-qi medicine that can both activate blood and promote qi. In preparations, Chuanxiong can improve the poor circulation of qi and blood in the shoulders, neck, waist and legs by activating blood and promoting qi. It has a good conditioning effect on pain caused by qi stagnation and blood stasis, and can guide other drugs to the diseased area.

[0187] Frankincense: Effects: Frankincense has the effects of promoting blood circulation, relieving pain, reducing swelling and promoting tissue regeneration. It helps to dissipate local blood stasis and relieve pain. At the same time, it has a certain effect on relieving local muscle tension and inflammation caused by pain, and promotes the repair and regeneration of damaged tissues.

[0188] Myrrh: Effects: Myrrh has similar effects to frankincense, and can dissipate blood stasis, relieve pain, and reduce swelling and promote tissue regeneration. In preparations, it can work with frankincense and other drugs to enhance the effects of promoting blood circulation, removing blood stasis, relieving pain and reducing swelling, and improve pain and inflammation in the shoulder, neck, waist and legs.

[0189] Dracaena: Effects: Dracaena has the effects of promoting blood circulation and relieving pain, removing blood stasis and stopping bleeding, promoting tissue regeneration and healing sores. In external application preparations, Dracaena can promote local blood circulation, dissipate blood stasis, relieve pain, and help repair damaged skin and tissues. It has a certain therapeutic effect on skin damage or inflammation that may exist in the painful areas of the shoulders, neck, waist and legs.

[0190] 2. Warming meridians and unblocking collaterals herbs:

[0191] Mugwort: Effects: Mugwort has the effects of warming the meridians and stopping bleeding, dispelling cold and relieving pain, removing dampness and relieving itching. In this preparation, its properties of warming the meridians and dispelling cold are mainly used. For pain in the shoulders, necks, waists and legs caused by cold evil stagnation of meridians, mugwort can dispel cold evil through its warm power, unblock the meridians, and allow the normal flow of qi and blood, thereby relieving pain.

[0192] Cinnamon twig: Effect: Cinnamon twig can induce sweating and relieve muscle pain, warm and dredge the meridians, and help yang and transform qi. In preparations, the warming and dredge meridians effect of cinnamon twig helps improve blood circulation in the shoulders, neck, waist and legs, especially for symptoms such as pain and limb numbness caused by cold stagnation in the meridians, and can promote the circulation of yang qi and dispel cold evil.

[0193] Dried ginger: Effect: Dried ginger has the effects of warming the middle and dispelling cold, restoring yang and unblocking meridians, and warming the lungs and transforming phlegm. In this external application preparation, the warming and dispelling cold effects of dried ginger can be used to improve the cold pain symptoms caused by the invasion of cold evil in the shoulder, neck, waist and legs, enhance the local warm feeling, promote the circulation of qi and blood, and relieve pain.

[0194] Gentiana macrophylla: Effect: Gentiana macrophylla has the effects of removing rheumatism, clearing dampness and heat, relieving pain and reducing deficiency fever. In the treatment of shoulder, neck, waist and leg pain, Gentiana macrophylla mainly plays the role of removing rheumatism and relieving pain, and can alleviate the pain caused by rheumatism blocking the meridians, and the symptoms of poor flexion and extension of joints.

[0195] Drynaria: Effect: Drynaria has the effects of healing and relieving pain, nourishing the kidney and strengthening bones. In preparations, Drynaria can heal and relieve pain caused by injuries or insufficient kidney qi in the shoulder, neck, waist and legs, and at the same time help to strengthen the function of bones and muscles and promote the repair of injuries.

[0196] 3. Qi-tonifying and blood-nourishing herbs:

[0197] Codonopsis: Effect: Codonopsis has the effects of tonifying the middle and replenishing qi, strengthening the spleen and benefiting the lungs. In preparations, although it is mainly used to treat pain in the shoulders, neck, waist and legs, replenishing qi helps to enhance the body's resistance and repair capabilities, enabling the body to better cope with pain and injury, and providing a good physical foundation for other drugs to work.

[0198] Astragalus: Effects: Astragalus can replenish qi and raise yang, consolidate the exterior and stop sweating, promote diuresis and reduce swelling, promote the production of body fluids and nourish blood, relieve stagnation and relieve numbness, remove toxins and discharge pus, and heal sores and promote tissue regeneration. In this preparation, the qi-replenishing effect of Astragalus can enhance the body's yang, improve the condition of local qi and blood deficiency, help relieve pain in the shoulders, necks, waists and legs caused by qi and blood deficiency, and also promote the absorption and effect of the drug.

[0199] Ginseng: Effects: Ginseng has the effects of replenishing vital energy, restoring pulse and strengthening deficiency, nourishing spleen and lung, promoting body fluid and nourishing blood, calming nerves and improving intelligence. In preparations, ginseng replenishes vital energy and can enhance the overall functional state of the human body. For pain in the shoulders, neck, waist and legs caused by insufficient vital energy, ginseng can provide enough energy to support the body's self-repair and help other drugs to exert their efficacy.

[0200] Rehmannia root: Effect: Rehmannia root has the effects of nourishing yin and blood, replenishing essence and filling marrow. In the preparations for treating shoulder, neck, waist and leg pain, blood nourishment helps nourish local muscles, bones and meridians, and has a certain effect on relieving pain caused by blood deficiency that cannot nourish tendons and veins, and also provides a material basis for the body's repair.

[0201] Angelica: Effect: Angelica has the effects of nourishing blood, activating blood circulation, regulating menstruation and relieving pain, and moistening the intestines and relieving constipation. In preparations, Angelica can both nourish blood and activate blood circulation, improve pain caused by blood deficiency and blood stasis in the shoulders, neck, waist and legs, regulate local qi and blood circulation, and promote nutrition supply and metabolism in the painful area.

[0202] Atractylodes macrocephala: Effect: Atractylodes macrocephala has the effects of strengthening the spleen and replenishing qi, drying dampness and promoting diuresis, stopping sweating, and calming the fetus. Here, the spleen-strengthening and qi-replenishing effects of Atractylodes macrocephala help improve the transportation and transformation functions of the spleen and stomach, making the qi and blood biochemically active, thereby providing the body with sufficient qi and blood to cope with pain and repair injuries in the shoulders, neck, waist and legs, and indirectly enhancing the effects of other drugs.

[0203] Poria: Function: Poria has the effects of promoting water and removing dampness, strengthening the spleen, and calming the mind. In the preparation, Poria regulates the body's water metabolism through the effects of strengthening the spleen and promoting water and removing dampness, helps to reduce local swelling and pain caused by stagnant water and dampness, and creates a good internal environment for other drugs to take effect.

[0204] Licorice: Effects: Licorice has the effects of tonifying the spleen and replenishing qi, clearing away heat and detoxifying, removing phlegm and relieving cough, relieving pain, and harmonizing various medicines. In this preparation, the relieving pain of licorice can directly relieve the pain symptoms of the shoulders, neck, waist and legs. At the same time, its function of harmonizing various medicines can make various medicines synergize with each other and reduce possible adverse reactions between drugs.

[0205] 4. Herbs for dispelling wind and dampness:

[0206] Clematis: Effect: Clematis has the effect of removing rheumatism and unblocking meridians. When treating pain in the shoulder, neck, waist and legs, Clematis can effectively remove the rheumatism in the meridians and make the meridians unblocked. It has a good effect on improving symptoms such as joint pain, limb numbness, and flexion and extension difficulties caused by rheumatism blocking the meridians.

[0207] Radix Glehniae Bark: Function: Radix Glehniae Bark is mainly used to dispel wind and dampness, promote qi and relieve pain. In preparations, Radix Glehniae Bark can target the rheumatic evil qi in the shoulders, neck, waist and legs, play a role in dispelling wind and dampness, thereby alleviating the pain and discomfort caused by rheumatism and improving the local joint activity function.

[0208] Stretching grass: Effect: Stretching grass can dispel wind and dampness, relax muscles and activate blood circulation. For patients with shoulder, neck, waist and leg pain, stretching grass can help stretch the tendons and veins, dispel rheumatism, relieve muscle tension, joint stiffness and pain caused by rheumatism or long-term strain, and improve the flexibility of limbs.

[0209] Qianghuo: Effect: Qianghuo has the effects of dispelling cold, expelling wind and dampness, and relieving pain. In preparations, Qianghuo is mainly used to dispel wind and dampness, relieve pain, and can relieve pain in the shoulders, neck, waist and legs caused by exogenous wind, cold and dampness or endogenous cold and dampness, especially for shoulder and neck pain in the upper body.

[0210] Duhuo: Effect: Duhuo has the effects of dispelling wind and dampness, relieving numbness and relieving pain. Different from Qianghuo, Duhuo focuses more on rheumatic pain in the lower body, and has a significant effect on treating pain in the waist and legs. It can improve symptoms such as lower limb pain, numbness, and flexion and extension difficulties caused by rheumatic arthralgia blocking the meridians.

[0211] Northern Liujinu: Effect: Northern Liujinu has the effects of promoting blood circulation and removing blood stasis, promoting menstruation and relieving pain, cooling blood and stopping bleeding, and clearing away heat and dampness. In the preparation, its effects of promoting blood circulation and removing blood stasis and promoting menstruation and relieving pain help to improve the pain caused by blood stasis or meridian obstruction in the shoulder, neck, waist and legs. At the same time, its effect of clearing heat and removing dampness can relieve the pain caused by damp-heat blocking the meridians.

[0212] Saposhnikovia divaricata: Function: Saposhnikovia divaricata has the effects of dispelling wind and relieving exterior symptoms, removing dampness and relieving pain, and stopping spasms. In preparations for treating pain in the shoulder, neck, waist and legs, Saposhnikovia divaricata can dispel wind evil, remove dampness and relieve pain. It has a good effect on improving pain caused by wind evil invasion or rheumatism, and can prevent wind evil from invading the human body again.

[0213] Turmeric: Effect: Turmeric has the effects of breaking blood and promoting qi, promoting menstruation and relieving pain. In preparations, turmeric can improve the stagnation of qi and blood in the shoulders, neck, waist and legs, promote menstruation and relieve pain, and relieve pain symptoms caused by poor qi and blood circulation or meridian blockage.

[0214] Mustard: Effect: Mustard has the effects of warming the lungs and dispelling phlegm, promoting qi and dispersing stagnation, and dredging meridians and relieving pain. In this preparation, mustard mainly plays the role of dredging meridians and relieving pain. It can dredge meridians and relieve pain caused by meridian blockage and qi and blood stagnation in the shoulder, neck, waist and legs.

[0215] 5. Other medicinal materials and excipients:

[0216] Pearl: Effect: Pearl has the effects of calming the nerves, improving eyesight, removing cataracts, detoxifying and promoting tissue regeneration. In topical preparations, pearl may help promote the repair of the skin in the painful area and reduce local inflammatory reactions. At the same time, its detoxifying and promoting tissue regeneration can play a certain therapeutic role on possible skin damage or inflammation.

[0217] Clove: Effect: Clove has the effects of warming the middle and lowering adverse reactions, nourishing the kidney and supporting yang. In preparations, the warming effect of clove can enhance the local sense of warmth, help dispel the evil of cold, and have a certain auxiliary effect on the pain in the shoulder, neck, waist and legs caused by cold stagnation in the meridians.

[0218] Eucommia: Effect: Eucommia has the effects of nourishing the liver and kidney, strengthening the tendons and bones, and calming the fetus. In the treatment of shoulder, neck, waist and leg pain, Eucommia can nourish the liver and kidney, strengthen the tendons and bones, and have a certain effect on improving the symptoms of weakness and pain caused by liver and kidney deficiency, and enhance the function of bones and muscles.

[0219] Tangerine peel: Function: Tangerine peel has the effects of regulating qi and strengthening the spleen, drying dampness and resolving phlegm. In preparations, the qi-regulating effect of tangerine peel helps regulate the circulation of qi and blood, allowing other drugs to better play the role of promoting blood circulation and removing blood stasis, dispelling wind and removing dampness, etc. At the same time, its function of drying dampness and resolving phlegm can improve the discomfort caused by local phlegm and dampness blockage.

[0220] Bupleurum: Effects: Bupleurum has the effects of dispersing fever, relieving liver depression, and raising Yang Qi. In this preparation, Bupleurum may help relieve shoulder, neck, waist and leg pain caused by Qi stagnation by regulating the body's Qi and allowing Qi and blood to flow smoothly, and can also raise Yang Qi and enhance the body's disease resistance.

[0221] Scorpion: Effect: Scorpion has the effects of calming wind and relieving spasms, unblocking meridians and relieving pain, and attacking toxins and dispersing nodules. In the preparation, the unblocking and analgesic effect of the scorpion can directly act on the meridians of the painful parts of the shoulders, neck, waist and legs, relieving pain symptoms, especially for those with more stubborn pain and severe meridian blockage.

[0222] Vegetable oil: Function: Vegetable oil, as a matrix, can moisturize the skin and make the drug adhere to the skin surface, which is convenient for the absorption of the drug. At the same time, it can prevent the drug from drying too quickly, maintain the contact time between the drug and the skin, and is conducive to the drug to take effect.

[0223] Propolis: Effect: Propolis has antibacterial and anti-inflammatory effects, as well as immunity-enhancing effects. In preparations, propolis can play an antibacterial and anti-inflammatory role, preventing infection at the site of application due to skin damage or inflammation. At the same time, its immunity-enhancing function helps the body better cope with pain and injury.

[0224] Pine soot toner: Effect: Pine soot toner may have certain astringent, hemostatic, and detumescent effects. In external application preparations, it can help reduce local swelling and pain, and promote astringency and repair of painful areas.

[0225] Camphor: Effect: Camphor has the effects of clearing the meridians, relieving stagnant qi, removing filth and turbidity, killing insects and relieving itching, and reducing swelling and relieving pain. In preparations, camphor can produce a cooling sensation, relieve local pain and inflammation, and at the same time, its effects of clearing the meridians and relieving stagnant qi help improve the condition of local qi and blood stagnation.

[0226] Menthol: Effect: Menthol has the effects of dispelling wind, clearing heat and detoxifying. In preparations, menthol can bring a cool feeling, relieve local pain and inflammation, and its effect of dispelling wind and clearing heat helps relieve pain in the shoulders, neck, waist and legs caused by wind-heat or damp-heat.

[0227] Treating both the symptoms and the root cause:

[0228] Activate blood circulation and remove blood stasis, warm the meridians and dredge the collaterals, dispel wind and dampness:

[0229] The blood-activating and stasis-removing herbs (such as safflower, Panax notoginseng, etc.), meridian-warming and collateral-draining herbs (such as mugwort leaves, cassia twigs, etc.), and wind-removing and dampness-removing herbs (such as clematis, smilax glabra, etc.) in this preparation are compatible with each other to provide comprehensive treatment for various causes of shoulder, neck, waist and leg pain. From the perspective of traditional Chinese medicine, blood stasis, cold stagnation in the meridians, and rheumatism are common causes of this type of pain. These herbs combined can not only remove pathological factors such as blood stasis, cold and dampness, and rheumatism (treating the symptoms), but also restore the body's normal physiological functions (treating the root cause) by regulating the circulation of qi and blood in the meridians.

[0230] Tonify Qi and blood, regulate internal organs:

[0231] The Qi-tonifying and blood-nourishing herbs in the formula (such as Codonopsis pilosula and Astragalus membranaceus) help replenish the body's positive Qi. In TCM theory, sufficient positive Qi can resist external pathogens and ensure smooth Qi and blood circulation. At the same time, some herbs, such as Eucommia ulmoides to nourish the liver and kidneys, and Tangerine peel to regulate Qi and strengthen the spleen, have a certain regulating effect on the functions of the internal organs. The liver and kidneys are nourished, and the tendons and bones are nourished; the spleen and stomach are healthy, and the Qi and blood are active. This regulation of the functions of the internal organs helps to fundamentally improve the pathogenesis of shoulder, neck, waist and leg pain.

[0232] Synergy:

[0233] Multiple medicinal materials can be combined according to the theory of traditional Chinese medicine to produce synergistic effects. For example, the combination of blood-activating and stasis-removing medicinal materials and meridian-warming and collateral-dredging medicinal materials can activate blood circulation and remove stasis on the basis of warming and unblocking the meridians, making blood stasis easier to dissipate and blood circulation smoother. The combination of wind-removing and dampness-removing medicinal materials and qi-replenishing and blood-nourishing medicinal materials can enhance the body's resistance while removing external evil, so that the evil can be removed without hurting the body, and the body can be strengthened without retaining the evil, thereby enhancing the effect of the entire preparation in treating shoulder, neck, waist and leg pain.

[0234] Multi-target effect:

[0235] Anti-inflammatory and analgesic:

[0236] Many medicinal materials have anti-inflammatory and analgesic pharmacological effects. For example, frankincense and myrrh contain volatile oils, resins and other ingredients, which have anti-inflammatory and analgesic effects; alkaloids such as genuine A and B in Gentiana macrophylla also have anti-inflammatory, analgesic and antipyretic effects. These ingredients can reduce inflammatory reactions in the shoulder, neck, waist and legs and relieve pain symptoms by inhibiting the release of inflammatory factors and regulating neurotransmitters.

[0237] 1. Improves Blood Circulation:

[0238] The safflower yellow pigment in safflower can dilate blood vessels, and the notoginseng saponins in Panax notoginseng can inhibit platelet aggregation and reduce blood viscosity. The ligustrazine in Chuanxiong can dilate blood vessels and improve microcirculation. Various medicinal materials improve the blood circulation of the shoulders, neck, waist and legs from different aspects, increase local blood supply, enable nutrients to better reach the painful area, and take away metabolic waste and inflammatory mediators, which helps to relieve pain and promote tissue repair.

[0239] Regulates immune function:

[0240] Some medicinal materials, such as propolis, contain a variety of compounds such as flavonoids and terpenes, which have immunomodulatory effects; saikosaponins in bupleurum can also regulate immune responses. In the treatment of shoulder, neck, waist and leg pain, regulating immune function helps the body better cope with the disease, enhances the body's resistance and prevents further deterioration of the disease.

[0241] Enhance drug absorption and duration of action:

[0242] The role of vegetable oil matrix:

[0243] Plant oil as a matrix can not only moisturize the skin and make the drug adhere to the skin surface better, but also prevent the drug from drying out too quickly. This is conducive to the long-term contact of the drug with the skin, promoting the absorption of the drug, allowing the drug to continue to work, prolonging the maintenance time of the treatment effect, and thus improving the treatment effect on shoulder, neck, waist and leg pain.

[0244] Wide applicability:

[0245] This preparation is suitable for shoulder, neck, waist and leg pain caused by various reasons. Whether it is blood stasis pain caused by trauma, cold stagnation pain caused by exogenous cold and dampness, or joint pain caused by diseases such as rheumatoid arthritis, this preparation can be used for treatment. Its combination of various medicinal materials covers the treatment needs of different causes and provides a comprehensive solution for clinical treatment.

[0246] Higher security:

[0247] Advantages of topical preparations:

[0248] As an external application preparation, it avoids the gastrointestinal adverse reactions that may be caused by oral medications. Especially for some patients with weak gastrointestinal function or adverse reactions to oral medications, external preparations are a relatively safe treatment option.

[0249] Safety of medicinal materials:

[0250] Although Chinese medicinal materials such as scorpion are used in the formula, the amount used in the external application preparation is carefully considered and formulated based on the experience of traditional Chinese medicine external application. At the same time, other medicinal materials such as cloves and wormwood are also commonly used external application materials in traditional Chinese medicine, and are relatively safe at normal dosages. In addition, the auxiliary materials in the preparation, such as vegetable oil and propolis, also have a certain degree of safety. Propolis itself has antibacterial and anti-inflammatory effects, which helps prevent infection at the external application site.

[0251] Ease of Use:

[0252] The topical preparation is easy to use and can be used by patients at home according to the instructions. It does not require special medical equipment or professional medical staff to operate. This is very convenient for patients with limited mobility or difficulty in seeking medical treatment, improves patient compliance, and is conducive to the treatment and recovery of the disease.

[0253] The present invention and its implementation methods are described above, and such description is not restrictive. In short, if ordinary technicians in the field are inspired by it and design methods and embodiments similar to the technical solution without creativity without departing from the purpose of the invention, they should all fall within the protection scope of the present invention.

Claims

1. A heating external application preparation for treating pain in the shoulder, neck, waist and legs and a preparation method thereof, characterized in that: include: 3-10g safflower, 3-9g Panax notoginseng, 3-10g Chuanxiong, 3-10g frankincense, 3-10g myrrh, 1-2g dragon's blood; Artemisia argyi 3-10g, cinnamon twig 3-10g, dried ginger 3-10g, gentiana macrophylla 3-10g, drynariae rhizome 3-10g; Codonopsis pilosula 9-30g, Astragalus membranaceus 9-30g, Ginseng 3-9g, Rehmannia root 9-15g, Angelica 6-12g, Atractylodes macrocephala 6-12g, Poria 9-15g, Licorice root 3-6g; Clematis 6-10g, Radix Glehniae 3-6g, Herba Lycopodii 9-15g, Radix Notopterygii 3-10g, Radix Angelicae Pubescentis 3-10g, Radix Angelicae Pubescentis 6-10g, Radix Saposhnikoviae 3-10g, Rhizoma Curcumae 3-10g, Semen Sinapis 3-6g; Pearl 3-6g, clove 1-3g, Eucommia ulmoides 6-10g, dried orange peel 3-10g, bupleurum 3-10g, scorpion 3-6g, vegetable oil 3-6g, propolis 3-6g, pine smoke powder 1-2g, camphor 1-2g, menthol 1-2g; It includes the steps of weighing medicinal materials, crushing medicinal materials, preparing matrix, preparing preparations and packaging; Weighing of medicinal materials: Accurately weigh each medicinal ingredient according to the type of medicinal ingredient in the formula and the average weight required for each; When weighing, use an accurate electronic scale to ensure that the weight of each medicinal material meets the requirements of the formula; Medicinal material crushing: Place the weighed Chinese medicinal materials in a cool and ventilated place to dry naturally or use an oven to dry at low temperature to remove excess moisture and prevent the medicinal materials from deteriorating; After drying, the medicinal materials are put into a traditional Chinese medicine grinder for crushing; Pearl treatment: Pearls need to be treated separately due to their hard texture; Put it into a special pulverizing device to grind it into extremely fine powder, and screen it through a 80-100 mesh screen; Grinding of other medicinal materials: Put the medicinal materials with lower hardness, such as mugwort leaves and cassia twigs, into the grinder and grind them. After grinding, pass them through a 60-80 mesh screen to ensure the fineness of the powder. Finally, the pearl powder is mixed evenly with other medicinal material powders to obtain the final mixed medicinal powder for later use; Matrix preparation: Choose a container, pour 3-6g of vegetable oil into it, and use a heating device (such as a hot plate) to heat the vegetable oil to 60-80℃; at this temperature, the vegetable oil can better dissolve other ingredients; Next, add 3-6g of propolis to the heated vegetable oil and continue stirring until the propolis is completely dissolved in the vegetable oil; Then, add 1-2g of pine smoke toner powder into the mixture and continue to stir evenly to ensure that the pine smoke toner powder is dispersed to form a stable matrix; Preparation of formulations: Slowly add the prepared mixed powder to the prepared matrix, turn on the stirring device, and keep the stirring speed between 200-300 rpm to ensure that the powder and the matrix are fully mixed to form a uniform drug paste; When the temperature of the paste drops to 40-50°C, add 1-2g of camphor and 1-2g of menthol, and continue stirring until the two ingredients are completely dissolved in the paste; Package: Packing the prepared herbal health cream into clean sealed bags or sealed containers according to the predetermined dosage; Maintain a sterile environment during the packaging process to avoid contamination; At the same time, the product name, production date, expiration date, usage, storage conditions and important information of precautions should be clearly marked on the packaging so that users can use it correctly.

2. A heating external application preparation for treating shoulder, neck, waist and leg pain according to claim 1 and its preparation method, characterized in that: include: 3g safflower, 3g Panax notoginseng, 3g Chuanxiong, 3g frankincense, 3g myrrh, 1g Sanguisorba officinalis; Artemisia argyi 3g, cinnamon twig 3g, dried ginger 3g, gentiana macrophylla 3g, drynariae rhizome 3g; Codonopsis pilosula 9g, Astragalus membranaceus 9g, Ginseng 3g, Rehmannia glutinosa 9g, Angelica sinensis 6g, Atractylodes macrocephala 6g, Poria 9g, Licorice root 3g; Clematis 6g, Radix Glehniae 3g, Herba Lycopodii 9g, Radix Notopterygii 3g, Radix Angelicae Pubescentis 3g, Radix Angelicae Pubescentis 6g, Radix Saposhnikoviae 3g, Rhizoma Curcumae 3g, Semen Sinapis 3g; Pearl 3g, clove 1g, Eucommia ulmoides 6g, tangerine peel 3g, bupleurum 3g, scorpion 3g, vegetable oil 3g, propolis 3g, pine smoke toner 1g, camphor 1g, menthol 1g.

3. A heating external application preparation for treating shoulder, neck, waist and leg pain according to claim 1 and its preparation method, characterized in that: include: 10g safflower, 9g Panax notoginseng, 10g Chuanxiong, 10g frankincense, 10g myrrh, 2g Sanguisorba officinalis; Artemisia argyi 10g, cinnamon twig 10g, dried ginger 10g, gentiana macrophylla 10g, drynariae rhizome 10g; Codonopsis pilosula 30g, Astragalus membranaceus 30g, Ginseng 9g, Rehmannia root 15g, Angelica 12g, Atractylodes macrocephala 12g, Poria 15g, Licorice root 6g; Clematis 10g, Radix Dipterae 6g, Herba Lycopodii 15g, Radix Notopterygii 10g, Radix Angelicae Pubescentis 10g, Radix Angelicae Pubescentis 10g, Radix Saposhnikoviae 10g, Rhizoma Curcumae 10g, Semen Sinapis 6g; Pearl 6g, clove 3g, Eucommia ulmoides 10g, tangerine peel 10g, bupleurum 10g, scorpion 6g, vegetable oil 6g, propolis 6g, pine smoke ink powder 2g, camphor 2g, menthol 2g.

4. A heating external application preparation for treating shoulder, neck, waist and leg pain and a preparation method thereof according to claim 1, characterized in that: include: 6.5g safflower, 6g Panax notoginseng, 6.5g Chuanxiong, 6.5g frankincense, 6.5g myrrh, 1.5g Sanguisorba officinalis, 6.5g of mugwort leaf, 6.5g of cinnamon twig, 6.5g of dried ginger, 6.5g of gentiana macrophylla, 6.5g of drynaria, Codonopsis pilosula 19.5g, Astragalus membranaceus 19.5g, Ginseng 6g, Rehmannia glutinosa 12g, Angelica sinensis 9g, Atractylodes macrocephala 9g, Poria 12g, Licorice root 4.5g, Clematis 8g, Radix Glehniae 4.5g, Herba Lycopodii 12g, Radix Notopterygii 6.5g, Radix Angelicae Pubescentis 6.5g, Radix Ligustici Nucifera 8g, Radix Saposhnikoviae 6.5g, Rhizoma Curcumae 6.5g, Semen Sinapis 4.5g, Pearl 4.5g, clove 2g, Eucommia ulmoides 8g, tangerine peel 6.5g, bupleurum 6.5g, scorpion 4.5g, vegetable oil 4.5g, propolis 4.5g, pine smoke toner 1.5g, camphor 1.5g, menthol 1.5g.