Drug injection device

Abstract

The present invention relates to a drug injection device, comprising: a drug solution chamber for storing a drug solution; a discharge unit which is provided in the liquid medicine chamber and through which the liquid medicine is discharged; and a laser light supply unit that supplies a pulsed laser light to the drug solution to generate bubbles that induce the volume of the drug solution to expand and disappear, thereby generating a shock wave that urges the drug solution toward the discharge unit.

Description

Technical Field

[0001] The invention relates to a medicine injection device. Background Art

[0002] A drug injection device is a device that effectively injects a required amount of drug into the body by minimizing the side effects produced in the conventional method and maximizing the therapeutic effect of the drug when using a drug for treating a disease or wound of the human body.

[0003] Although the common syringe, which is the most commonly used in drug injection devices, can accurately and effectively inject drugs, it is feared by patients due to the pain during injection, and there are inevitable problems such as the concern about infection caused by the wound.

[0004] In order to solve this problem, needle-free injectors have been developed.

[0005] For example, the needle-free syringe includes a pressure chamber for storing a working fluid, a drug liquid chamber combined with the pressure chamber and storing the drug liquid, an elastic membrane sandwiched between the pressure chamber and the drug liquid chamber, an injection nozzle equipped in the drug liquid chamber, and a heat energy transfer unit for transferring heat energy to the working fluid.

[0006] In the prior art, a heat energy transfer unit can transfer heat energy to a working fluid stored in a pressure chamber to generate bubbles. By means of shock waves generated by the rapid expansion and disappearance of such bubbles, the elastic membrane can stretch and deform toward the drug liquid chamber, thereby applying a propulsion pressure to the drug liquid stored in the drug chamber so that it can be discharged through the nozzle.

[0007] However, the prior art is composed of a pressure chamber, an elastic membrane, a drug chamber, a spray nozzle and an energy transfer unit, and thus has a problem of being very complex in structure. Summary of the invention

[0008] Technical issues The present invention is proposed to solve the above-mentioned problems. The object of the present invention is to provide a drug injection device which does not require a pressure chamber and an elastic membrane and can simplify the structure.

[0009] The technical problems to be solved by the present invention are not limited to the technical problems mentioned above, and ordinary technicians can clearly understand other technical problems not mentioned from the following records.

[0010] Technical Solution A drug injection device according to an embodiment of the present invention may include: a drug liquid chamber for storing drug liquid; a discharge portion provided in the drug liquid chamber for discharging the drug liquid; and a laser supply portion for supplying pulsed laser to the drug liquid to generate bubbles, wherein the bubbles induce the volume of the drug liquid to expand and disappear, thereby generating a shock wave that pushes the drug liquid toward the discharge portion.

[0011] Furthermore, the drug solution may be a liquid, a sol or a liquid phase substance that generates the bubbles by the pulse laser.

[0012] In addition, the drug injection device may further include: a drug liquid storage unit, storing the drug liquid to be supplied to the drug liquid chamber; and a check valve, so that the drug liquid stored in the drug liquid storage unit is transferred only to the drug liquid chamber, wherein after the drug liquid is discharged through the discharge unit, the drug liquid stored in the drug liquid storage unit can be injected into the drug liquid storage unit through the check valve by means of the negative pressure generated in the drug liquid chamber.

[0013] In addition, the drug injection device may also include: a temperature sensor for measuring the temperature of the drug stored in the drug liquid chamber; a flow sensor for measuring the flow rate of the drug liquid discharged through the discharge portion; a pressure sensor for measuring the pressure of the drug liquid stored in the drug liquid chamber; and a control portion for forcing the check valve to open when at least one of the temperature value measured by the temperature sensor, the flow value measured by the flow sensor, and the pressure value measured by the pressure sensor exceeds a set reference value, so that the drug liquid stored in the drug liquid storage portion is supplied to the drug liquid chamber.

[0014] Furthermore, the medical solution may include a filler.

[0015] Furthermore, the drug injection device may further include: a drug liquid guide provided at the discharge portion to guide the drug liquid discharged through the discharge portion to be sprayed in the form of fine particles.

[0016] Furthermore, the liquid medicine guide includes: a guide body, which is equipped on the discharge part to reduce the cross-sectional area of ​​the discharge part; and a guide groove, which is formed in a spiral shape on the outer peripheral surface of the guide body, wherein the liquid medicine discharged through the discharge part can flow along the guide groove while generating a vortex, thereby being sprayed in the form of fine particles.

[0017] Furthermore, the drug injection device may further include: a temperature adjustment unit for heating or cooling the drug solution stored in the drug solution chamber so that the temperature of the drug solution stored in the drug solution chamber is maintained at a set temperature.

[0018] Furthermore, the temperature regulating unit may include: a Peltier element, which is equipped in the drug liquid chamber to release cold heat or warm heat; and a current supply unit, which adjusts the direction of current applied to the Peltier element according to the set temperature so that the Peltier element releases cold heat or warm heat.

[0019] Furthermore, the drug liquid chamber may include a heat insulating material.

[0020] Furthermore, the drug injection device may further include: an auxiliary temperature adjustment unit, which is provided in the drug solution storage unit to heat or cool the drug solution stored in the drug solution chamber so that the temperature of the drug solution stored in the drug solution chamber is maintained at a set temperature.

[0021] Furthermore, the temperature regulating unit may include: an auxiliary Peltier element, which is equipped in the liquid medicine storage unit to release cold or warm heat; and an auxiliary current supply unit, which adjusts the direction of the current applied to the auxiliary Peltier element according to the set temperature so that the auxiliary Peltier element releases cold or warm heat.

[0022] In addition, the drug injection device may also include: a plunger, which is equipped in the drug liquid chamber and can be moved back and forth and approach the discharge part to apply pressure to discharge the drug liquid stored in the drug liquid chamber through the discharge part; a moving coil, which is equipped with the plunger; a first magnetic coil, which is equipped on one side of the drug liquid chamber and applies a magnetic force to make the moving coil approach the discharge part; and a second magnetic coil, which is equipped on the other side of the drug liquid chamber and applies a magnetic force to separate the moving coil from the discharge part.

[0023] Furthermore, the drug injection device may further include: a current applying unit for a moving coil, applying a pulse current to the moving coil; a current applying unit for a first magnetic coil, applying a pulse current to the first magnetic coil; and a current applying unit for a second magnetic coil, applying a pulse current to the second magnetic coil.

[0024] Beneficial Effects The drug injection device according to an embodiment of the present invention does not require a pressure chamber and an elastic membrane, thereby having an effect of being able to simplify the structure.

[0025] The effects of the present invention are not limited to the effects mentioned above, and those skilled in the art can clearly understand other effects not mentioned through the following description. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 is a cross-sectional view showing a medicine injection device according to a first embodiment of the present invention.

[0027] Figures 2 to 41 is a cross-sectional view showing a process of injecting a medicine into the skin by the medicine injection device according to the first embodiment of the present invention.

[0028] Figure 5 is a cross-sectional view showing a medicine injection device according to a second embodiment of the present invention.

[0029] Figure 6 is a cross-sectional view showing a medicine injection device according to a third embodiment of the present invention.

[0030] Figure 7 is a cross-sectional view showing a medicine injection device according to a fourth embodiment of the present invention.

[0031] Figure 8 is a cross-sectional view showing a medicine injection device according to a fifth embodiment of the present invention.

[0032] Figures 9 to 11 4 is a cross-sectional view showing a process of injecting a medicine into the skin by the medicine injection device according to the fifth embodiment of the present invention.

[0033] Fig.12 is a cross-sectional view showing a medicine injection device according to a sixth embodiment of the present invention.

[0034] Fig.13 is a cross-sectional view showing a medicine injection device according to a seventh embodiment of the present invention.

[0035] Fig.14 is a cross-sectional view showing a medicine injection device according to an eighth embodiment of the present invention.

[0036] Fig.15 is a cross-sectional view showing a medicine injection device according to a ninth embodiment of the present invention.

[0037] Fig.16 is a cross-sectional view showing a state in which a medicine is discharged by a medicine injection device according to a ninth embodiment of the present invention. DETAILED DESCRIPTION

[0038] The advantages, features and methods for achieving the advantages, features and methods of the present invention can be clearly understood by referring to the embodiments described in detail below in conjunction with the accompanying drawings. However, the present invention is not limited to the embodiments disclosed below, and can be implemented in various forms that are different from each other. The present embodiments are provided only to complete the disclosure of the present invention and to fully inform the ordinary technicians in the technical field to which the present invention belongs. The present invention is only defined by the scope of the claims.

[0039] Unless otherwise defined, all terms (including technical and scientific terms) used in this specification may be used with the meanings commonly understood by those skilled in the art in the art to which the present invention belongs. Furthermore, for terms defined in commonly used dictionaries, unless otherwise clearly and specifically defined, they should not be idealized or over-interpreted.

[0040] Before describing the present invention, in a plurality of embodiments, components having the same configuration are denoted by the same reference numerals, and a first embodiment will be representatively described, while in other embodiments, configurations different from the first embodiment will be described.

[0041] Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

[0042] Figure 1 1 is a cross-sectional view showing a drug injection device according to a first embodiment of the present invention.

[0043] like Figure 1 As shown, the drug injection device according to the first embodiment of the present invention may include a drug liquid chamber 100 , a discharge part 200 , and a laser supply part 300 .

[0044] The medical fluid chamber 100 stores the medical fluid 10. Specifically, the medical fluid chamber 100 may have a sealed storage space inside, and the medical fluid 10 may be stored in such storage space.

[0045] The drug liquid chamber 100 may be formed in a cylindrical shape. The drug liquid chamber 100 may be provided with a discharge unit 200 which will be described later.

[0046] The discharge unit 200 is provided in the drug liquid chamber 100 and is used to discharge the drug liquid 10. Here, the driving principle of discharging the drug liquid 10 from the drug liquid chamber 100 through the discharge unit 200 will be described later. For example, the discharge unit 200 may have a linear shape, a spray nozzle shape, or a needle shape, but the present invention is not particularly limited thereto, and other shapes may also be applied.

[0047] The discharge portion 200 may be formed in a hole shape on the lower side of the drug liquid chamber 100. The drug discharge speed may be determined according to the diameter of such a discharge portion 200. For example, the diameter of the discharge portion 200 may be 50 microns to 1000 microns. However, in a case where the diameter of the discharge portion 200 is less than 50 microns, the amount of the drug liquid 10 discharged from the discharge portion 200 is relatively small, and thus the drug liquid 10 may not be injected into the skin at a sufficient depth. Also, in a case where the diameter of the discharge portion 200 exceeds 1000 microns, the amount of the drug liquid 10 discharged from the discharge portion 200 is relatively large, and thus the amount of the drug liquid 10 that cannot be injected into the skin and is ejected increases. Therefore, preferably, the diameter of the discharge portion 200 is limited to the above-mentioned value.

[0048] The laser supply unit 300 supplies pulsed laser to the drug solution 10 to generate bubbles 20. Such bubbles 20 can induce the volume of the drug solution 10 to expand and disappear, thereby generating a shock wave that pushes the drug solution 10 toward the discharge unit 200. As a result, the drug solution 10 can be discharged from the drug solution chamber 100 through the discharge unit 200.

[0049] For example, the laser supply unit 300 may supply a pulse laser oscillating at 10 Hz to 40 Hz for 1 second to the chemical solution 10 .

[0050] In addition, when the bubbles 20 are generated and the volume of the drug solution 10 expands, a positive pressure may be formed in the drug solution chamber 100. Thereafter, the bubbles 20 may disappear and generate a shock wave to discharge the drug solution 10 from the drug solution chamber 100 through the discharge portion 200, and a negative pressure may be formed in the drug solution chamber 100.

[0051] The drug solution 10 used in the drug injection device according to one embodiment of the present invention may be a liquid, sol or liquid-phase substance that generates bubbles 20 by pulsed laser. In other words, the drug solution 10 may be a liquid, sol or liquid-phase substance that generates bubbles by absorbing pulsed laser and causing the liquid molecular structure to collapse (breakdown). For example, the drug solution 10 may be a filler or water. Here, the filler may be a filler of a polymer series, specifically, polylactic acid (PLA: Poly LacticAcid), poly-DL-lactic acid (PDLA, Poly-DL-lactic acid), polycaprolactone (PCL: Poly Caprolactone) or polydioxanone (PDO: polydioxanone).

[0052] In one embodiment, when the drug solution 10 stored in the drug solution chamber 100 is a polymer-series filler, even if a pulsed laser is applied instantaneously to the polymer-series filler, due to the characteristics of the polymer-series filler, the temperature is likely to rise and soften, and the polymer-series filler is likely to decompose rapidly, so that the polymer-series filler is easily injected into the skin, thereby imparting a collagen regeneration effect to the internal tissues of the skin.

[0053] The following describes the process of injecting medicine into the skin by the medicine injection device according to the first embodiment of the present invention. The control unit 600 may also perform the following process. Furthermore, the following process may also be applicable to the second to fourth embodiments.

[0054] Figures 2 to 4 1 is a cross-sectional view showing a process of injecting a medicine into the skin by the medicine injection device according to the first embodiment of the present invention.

[0055] First, if Figure 2As shown, the laser supply unit 300 supplies pulse laser light to a specific position of the chemical solution 10 filled in the chemical solution chamber 100 .

[0056] Next, if Figure 3 As shown, the molecular structure of the chemical solution 10 that absorbs the pulse laser light collapses, and bubbles 20 are generated.

[0057] Then, if Figure 4 As shown, the bubbles 20 generated in the liquid chamber 100 induce the volume of the liquid medicine 10 to expand and disappear, thereby generating a shock wave that pushes the liquid medicine 10 toward the discharge part 200. As a result, the liquid medicine 10 can be discharged from the liquid chamber 100 through the discharge part 200.

[0058] In the past, the heat energy transfer unit transferred heat energy to the working fluid stored in the pressure chamber to generate bubbles. The elastic membrane was stretched and deformed toward the medicine chamber by the shock wave generated by the rapid expansion and disappearance of the bubbles. As a result, a propulsion pressure was applied to the medicine stored in the medicine chamber and discharged through the nozzle. Moreover, since it is composed of a pressure chamber, an elastic membrane, a medicine chamber, a nozzle and an energy transfer unit, its structure is very complicated.

[0059] On the contrary, in the drug injection device according to the first embodiment of the present invention, even without a pressure chamber and an elastic membrane, the laser supply unit 300 can directly supply pulsed laser to the drug liquid 10 stored in the drug liquid chamber 100 to generate bubbles 20. Such bubbles 20 induce the volume of the drug liquid to expand and disappear, and the drug liquid 10 stored in the drug liquid chamber 100 is discharged by the generated shock wave. Therefore, a pressure chamber and an elastic membrane are not required, thereby simplifying the structure.

[0060] Figure 5 is a cross-sectional view showing a medicine injection device according to a second embodiment of the present invention.

[0061] like Figure 5 As shown, different from the first embodiment, the drug injection device according to the second embodiment of the present invention may further include a drug solution storage portion 400 , a check valve 500 and a control portion 600 .

[0062] The drug liquid storage part 400 stores the drug liquid 10 to be supplied to the drug liquid chamber 100. For example, the drug liquid storage part 400 may use a drug liquid tank storing the drug liquid 10.

[0063] The check valve 500 can transfer the medical solution 10 stored in the medical solution storage part 400 only to the medical solution chamber 100 .

[0064] Therefore, in this embodiment, after the medical solution is discharged through the discharge portion 200 , the medical solution 10 stored in the medical solution storage portion 400 may be injected into the medical solution storage portion 400 through the check valve 500 by the negative pressure generated in the medical solution chamber 100 .

[0065] The drug injection device according to the second embodiment of the present invention may further include a temperature sensor 710 , a flow sensor 720 , a pressure sensor 730 and a control unit 600 .

[0066] The temperature sensor 710 may measure the temperature of the medical solution 10 stored in the medical solution chamber 100 . The temperature sensor 710 may be provided in the medical solution chamber 100 .

[0067] The flow sensor 720 can measure the flow rate of the medical solution 10 discharged through the discharge unit 200. Such a flow sensor 720 can be provided in the discharge unit 200.

[0068] The pressure sensor 730 may measure the pressure of the medical solution 10 stored in the medical solution chamber 100 . The pressure sensor 730 may be provided in the medical solution chamber 100 .

[0069] When at least one of the temperature value measured by the temperature sensor 710, the flow value measured by the flow sensor 720, and the pressure value measured by the pressure sensor 730 exceeds a set reference value, the control unit 600 may forcibly open the check valve 500 so that the medical solution 10 stored in the medical solution storage unit 400 is supplied to the medical solution chamber 100. Here, in the control unit 600, the set reference value for the temperature value may be 37 to 40 degrees, the set reference value for the flow value may be 3 ml to 4 ml, and the set reference value for the pressure value may be 1 atmospheric pressure.

[0070] Figure 6 is a cross-sectional view showing a medicine injection device according to a third embodiment of the present invention.

[0071] like Figure 6 As shown, unlike the first embodiment, the drug injection device according to the third embodiment of the present invention may further include a drug liquid guide 800 .

[0072] The liquid medicine guide 800 may be provided at the discharge portion 200 to guide the liquid medicine 10 discharged through the discharge portion 200 to be sprayed in the form of fine particles. The liquid medicine guide 800 may include a guide body 810 and a guide groove 820 .

[0073] The guide body 810 is provided at the discharge portion 200 , thereby playing a role of reducing the cross-sectional area of ​​the discharge portion 200 .

[0074] The guide groove 820 may be formed in a spiral shape on the outer circumferential surface of the guide body 810 .

[0075] Therefore, the drug solution 10 discharged from the discharge unit 200 flows along the guide groove 820 and generates a vortex, so that it can be sprayed in the form of fine particles.

[0076] The fine particles sprayed through the discharge unit 200 in this way have a very small diameter and a very slow flow rate, and thus can easily pass through the skin surface and be easily injected into the deep part of the skin.

[0077] Figure 7 is a cross-sectional view showing a medicine injection device according to a fourth embodiment of the present invention.

[0078] like Figure 7 As shown, unlike the first embodiment, in the drug injection device according to the fourth embodiment of the present invention, a plurality of protrusions 110 may be formed on the lower side of the drug liquid chamber 100 , and a plurality of discharge portions 200 may be respectively provided to the plurality of protrusions 110 .

[0079] The protrusion 110 may have a shape in which the diameter decreases as it approaches the skin.

[0080] Therefore, in the present embodiment, as the drug is discharged through the plurality of discharge parts 200 , the drug injection range of the skin can be expanded.

[0081] Figure 8 is a cross-sectional view showing a medicine injection device according to a fifth embodiment of the present invention.

[0082] like Figure 8 As shown, the drug injection device according to the fifth embodiment of the present invention may include a drug liquid chamber 100 , a discharge portion 200 , a laser supply portion 300 , and a temperature adjustment portion 900 .

[0083] The medical fluid chamber 100 stores the medical fluid 10. Specifically, the medical fluid chamber 100 may have a sealed storage space inside, and the medical fluid 10 may be stored in such storage space.

[0084] The drug liquid chamber 100 may be formed in a cylindrical shape. The drug liquid chamber 100 may be provided with a discharge unit 200 described later.

[0085] In one embodiment, the drug liquid chamber 100 can maintain a set temperature by the temperature adjustment unit 900 described later. At this time, in order to minimize the heat loss of the drug liquid chamber 100, the drug liquid chamber 100 can include a heat insulating material. For example, the heat insulating material can include foamed polystyrene.

[0086] The discharge unit 200 is provided in the drug liquid chamber 100 and is used to discharge the drug liquid 10. Here, the driving principle of discharging the drug liquid 10 from the drug liquid chamber 100 through the discharge unit 200 will be described later. For example, the discharge unit 200 may have a linear shape, a spray nozzle shape, or a needle shape, but the present invention is not particularly limited thereto, and other shapes may also be applied.

[0087] The discharge portion 200 may be formed in a hole shape on the lower side of the drug liquid chamber 100. The drug discharge speed may be determined according to the diameter of such a discharge portion 200. For example, the diameter of the discharge portion 200 may be 50 microns to 1000 microns. However, in a case where the diameter of the discharge portion 200 is less than 50 microns, the amount of the drug liquid 10 discharged from the discharge portion 200 is relatively small, and thus the drug liquid 10 may not be injected into the skin at a sufficient depth. Also, in a case where the diameter of the discharge portion 200 exceeds 1000 microns, the amount of the drug liquid 10 discharged from the discharge portion 200 is relatively large, and thus the amount of the drug liquid 10 that cannot be injected into the skin and is ejected increases. Therefore, preferably, the diameter of the discharge portion 200 is limited to the above-mentioned value.

[0088] The laser supply unit 300 supplies pulsed laser light to the drug solution 10 to generate bubbles 20. Such bubbles 20 can induce the volume expansion of the drug solution 10 and then disappear, thereby generating a shock wave that pushes the drug solution 10 toward the discharge unit 200. As a result, the drug solution 10 can be discharged from the drug solution chamber 100 through the discharge unit 200. At this time, the drug solution 10 discharged through the discharge unit 200 can be injected deep into the skin.

[0089] For example, the laser supply unit 300 may supply a pulse laser oscillating at 10 Hz to 40 Hz for 1 second to the chemical solution 10 .

[0090] In addition, when the bubbles 20 are generated and the volume of the drug solution 10 expands, a positive pressure may be formed in the drug solution chamber 100. Thereafter, the bubbles 20 may disappear and generate a shock wave, and after the drug solution 10 is discharged from the drug solution chamber 100 through the discharge portion 200, a negative pressure may be formed in the drug solution chamber 100.

[0091] The temperature adjustment part 900 can heat or cool the drug solution 10 stored in the drug solution chamber 100, so that the temperature of the drug solution stored in the drug solution chamber 100 is maintained at a set temperature. Therefore, as the temperature of the drug solution stored in the drug solution chamber 100 is maintained at a set temperature by the temperature adjustment part 900, the drug solution 10 discharged through the discharge part 200 and injected into the deep part of the skin can transfer warm or cold heat to the deep part of the skin.

[0092] In one embodiment, the temperature adjustment unit 900 can heat or cool the drug liquid chamber 100 based on the temperature of the drug liquid measured by the temperature sensor 710 described later, so that the temperature of the drug liquid stored in the drug liquid chamber 100 is maintained at a set temperature. In addition, the temperature adjustment unit 900 can be controlled by the control unit 600 described later.

[0093] In another embodiment, the set temperature of the temperature adjustment part 900 may be -10°C to 50°C.

[0094] For example, when the temperature setting of the temperature adjustment part 900 is -10°C to 40°C, the liquid medicine 10 discharged through the discharge part 200 and injected into the deep part of the skin can transfer heat and cold to the deep part of the skin. At this time, when the temperature setting of the temperature adjustment part 900 is -10°C to 0°C, an antifreeze such as glycerin is mixed in the liquid medicine 10, thereby preventing the liquid medicine 10 from freezing. Furthermore, when the liquid medicine at -10°C to 0°C is injected into the deep part of the skin, it can be used to treat keloids, raised skin and skin scars in the deep part of the skin.

[0095] Furthermore, when the set temperature of the temperature adjustment part 900 is 40° C. to 50° C., the medicinal solution 10 discharged through the discharge part 200 and injected into the deep part of the skin can transmit heat to the deep part of the skin.

[0096] The temperature adjustment unit 900 may include a Peltier element 910 and a current supply unit 920 .

[0097] The Peltier element 910 is provided in the liquid medicine chamber 100, and plays the role of releasing cold or heat or warm. For example, for the Peltier element 910, if the current is applied in the positive direction, one side can release cold or heat, and the other side can release warm heat. If the current is applied in the reverse direction, one side can release warm heat, and the other side can release cold or heat. Referring to this example, one side of the Peltier element 910 can be in contact with the liquid medicine 10 stored in the liquid medicine chamber 100, and the other side can be combined with the inner surface of the liquid medicine chamber 100. If the current is applied to the Peltier element 910 in the positive direction, the cold or heat can be released from one side of the Peltier element 910 to the liquid medicine 10 stored in the liquid medicine chamber 100. And, if the current is applied to the Peltier element 910 in the reverse direction, the warm heat can be released from one side of the Peltier element 910 to the liquid medicine 10 stored in the liquid medicine chamber 100.

[0098] The current supply unit 920 can adjust the direction of the current applied to the Peltier element 910 according to the set temperature so that the Peltier element 910 releases cold heat or warm heat. As in the example described above, when one side of the Peltier element 910 is in contact with the drug liquid chamber 100 and the other side of the Peltier element 910 is not in contact with the drug liquid chamber 100, if the current supply unit 920 applies current to the Peltier element 910 in the forward direction, cold heat can be released from one side of the Peltier element 910 to the drug liquid 10 stored in the drug liquid chamber 100, and if the current supply unit 920 applies current to the Peltier element 910 in the reverse direction, warm heat can be released from one side of the Peltier element 910 to the drug liquid 10 stored in the drug liquid chamber 100.

[0099] The drug solution 10 used in the drug injection device according to one embodiment of the present invention may be a liquid, sol or liquid-phase substance that generates bubbles 20 by pulsed laser. In other words, the drug solution 10 may be a liquid, sol or liquid-phase substance that generates bubbles by absorbing pulsed laser and causing the liquid molecular structure to collapse (breakdown). For example, the drug solution 10 may be a filler or water. Here, the filler may be a filler of a polymer series, specifically, polylactic acid (PLA: Poly LacticAcid), poly-DL-lactic acid (PDLA, Poly-DL-lactic acid), polycaprolactone (PCL: Poly Caprolactone) or polydioxanone (PDO: polydioxanone).

[0100] In one embodiment, when the drug solution 10 stored in the drug solution chamber 100 is a polymer-series filler, even if a pulsed laser is applied instantaneously to the polymer-series filler, the temperature of the polymer-series filler is likely to rise and soften, causing rapid decomposition of the polymer-series filler, and the polymer-series filler is easily injected into the skin, thereby imparting a collagen regeneration effect to the internal tissues of the skin.

[0101] Hereinafter, the process of injecting medicine into the skin by the medicine injection device according to the fifth embodiment of the present invention will be described. The control unit 600 may also perform the following process. Furthermore, the following process may also be applicable to the sixth to eighth embodiments.

[0102] Figures 9 to 11 4 is a cross-sectional view showing a process of injecting a medicine into the skin by the medicine injection device according to the fifth embodiment of the present invention.

[0103] First, the temperature regulating unit 900 heats or cools the drug 10 stored in the drug chamber 100 so that the temperature of the drug 10 stored in the drug chamber 100 is maintained at the set temperature. For example, when the set temperature is lower than the set temperature of the drug stored in the drug chamber 100, the temperature regulating unit 900 may heat the drug chamber 100. Also, when the set temperature is lower than the set temperature of the drug stored in the drug chamber 100, the temperature regulating unit 900 may cool the drug chamber 100. At this time, the auxiliary temperature regulating unit 1000 described later may heat or cool the drug 10 stored in the drug storage unit 400 so that the temperature of the drug 10 stored in the drug storage unit 400 described later is maintained at the set temperature.

[0104] Afterwards, if Fig. 9 As shown, the laser supply unit 300 supplies pulse laser light to a specific position of the chemical solution 10 filled in the chemical solution chamber 100 .

[0105] Next, if Fig.10As shown, the molecular structure of the chemical solution 10 that absorbs the pulse laser light collapses, and bubbles 20 are generated.

[0106] Then, if Fig.11 As shown, the bubbles 20 generated in the drug liquid chamber 100 induce the volume expansion of the drug liquid 10 and disappear, thereby generating a shock wave that drags the drug liquid 10 to the discharge portion 200. As a result, the drug liquid 10 can be discharged from the drug liquid chamber 100 through the discharge portion 200. The drug liquid 10 discharged in this way is injected into the deep part of the skin, so that it can transmit heat or cold to the deep part of the skin.

[0107] In the past, the heat energy transfer unit transferred heat energy to the working fluid stored in the pressure chamber to generate bubbles. The elastic membrane was stretched and deformed toward the medicine chamber by the shock wave generated by the rapid expansion and disappearance of the bubbles. As a result, a propulsion pressure was applied to the medicine stored in the medicine chamber and discharged through the nozzle. Moreover, since it is composed of a pressure chamber, an elastic membrane, a medicine chamber, a nozzle and an energy transfer unit, its structure is very complicated.

[0108] On the contrary, in the drug injection device according to the first embodiment of the present invention, even without a pressure chamber and an elastic membrane, the laser supply unit 300 can directly supply pulsed laser to the drug liquid 10 stored in the drug liquid chamber 100 to generate bubbles 20. Such bubbles 20 induce the volume of the drug liquid to expand and disappear, and the drug liquid 10 stored in the drug liquid chamber 100 is discharged by the generated shock wave. Therefore, a pressure chamber and an elastic membrane are not required, thereby simplifying the structure.

[0109] Fig.12 is a cross-sectional view showing a medicine injection device according to a sixth embodiment of the present invention.

[0110] like Fig.12 As shown, different from the fifth embodiment, the drug injection device according to the sixth embodiment of the present invention may further include a drug liquid storage portion 400 , a check valve 500 and a control portion 600 .

[0111] The drug liquid storage part 400 stores the drug liquid 10 to be supplied to the drug liquid chamber 100. For example, the drug liquid storage part 400 may use a drug liquid tank storing the drug liquid 10.

[0112] The check valve 500 can transfer the medical solution 10 stored in the medical solution storage part 400 only to the medical solution chamber 100 .

[0113] Therefore, in this embodiment, after the medical solution is discharged through the discharge portion 200 , the medical solution 10 stored in the medical solution storage portion 400 may be injected into the medical solution storage portion 400 through the check valve 500 due to the negative pressure generated in the medical solution chamber 100 .

[0114] The medicine injection device according to the sixth embodiment of the present invention may further include a temperature sensor 710 , a flow sensor 720 , a pressure sensor 730 and a control unit 600 .

[0115] The temperature sensor 710 may measure the temperature of the medical solution 10 stored in the medical solution chamber 100 . The temperature sensor 710 may be provided in the medical solution chamber 100 .

[0116] The flow sensor 720 can measure the flow rate of the medical solution 10 discharged through the discharge unit 200. Such a flow sensor 720 can be provided in the discharge unit 200.

[0117] The pressure sensor 730 may measure the pressure of the medical solution 10 stored in the medical solution chamber 100 . The pressure sensor 730 may be provided in the medical solution chamber 100 .

[0118] When at least one of the temperature value measured by the temperature sensor 710, the flow value measured by the flow sensor 720, and the pressure value measured by the pressure sensor 730 exceeds a set reference value, the control unit 600 may forcibly open the check valve 500 so that the medical solution 10 stored in the medical solution storage unit 400 is supplied to the medical solution chamber 100. Here, in the control unit 600, the set reference value for the temperature value may be 37 to 40 degrees, the set reference value for the flow value may be 3 ml to 4 ml, and the set reference value for the pressure value may be 1 atmospheric pressure.

[0119] Furthermore, the medicine injection device according to the sixth embodiment of the present invention may further include an auxiliary temperature regulating part 1000 .

[0120] The auxiliary temperature adjustment unit 1000 may be provided in the chemical liquid storage unit 400 , and may heat or cool the chemical liquid stored in the chemical liquid storage unit 400 to maintain the temperature of the chemical liquid stored in the chemical liquid storage unit 400 at a set temperature.

[0121] Furthermore, the auxiliary temperature adjustment unit 1000 may include an auxiliary Peltier element 1010 and an auxiliary current supply unit 1020 .

[0122] The auxiliary Peltier element 1010 can be equipped in the liquid medicine storage unit 400 and can release cold or warm. The working principle of the auxiliary Peltier element 1020 is different only in that the applicable object is the liquid medicine storage unit 400, which can be the same as the Peltier element 910.

[0123] The auxiliary current supply unit 1020 can adjust the direction of the current applied to the auxiliary Peltier element 1010 according to the set temperature, so that the auxiliary Peltier element 1010 releases cold or warm heat. The working principle of this auxiliary current supply unit 1020 is different only in that the applicable object is the auxiliary Peltier element 1020, which can be the same as the auxiliary Peltier element 910.

[0124] Fig.13 is a cross-sectional view showing a medicine injection device according to a seventh embodiment of the present invention.

[0125] like Fig.13 As shown, unlike the fifth embodiment, the drug injection device according to the seventh embodiment of the present invention may further include a drug liquid guide 800 .

[0126] The liquid medicine guide 800 may be provided at the discharge portion 200 to guide the liquid medicine 10 discharged through the discharge portion 200 to be sprayed in the form of fine particles. The liquid medicine guide 800 may include a guide body 810 and a guide groove 820 .

[0127] The guide body 810 is provided at the discharge portion 200 , thereby playing a role of reducing the cross-sectional area of ​​the discharge portion 200 .

[0128] The guide groove 820 may be formed in a spiral shape on the outer circumferential surface of the guide body 810 .

[0129] Therefore, the drug solution 10 discharged from the discharge unit 200 flows along the guide groove 820 and generates a vortex, so that it can be sprayed in the form of fine particles.

[0130] The fine particles sprayed through the discharge unit 200 in this way have a very small diameter and a very slow flow rate, and thus can easily pass through the skin surface and be easily injected into the deep part of the skin.

[0131] Fig.14 is a cross-sectional view showing a medicine injection device according to an eighth embodiment of the present invention.

[0132] like Fig.14 As shown, unlike the fifth embodiment, in the drug injection device according to the eighth embodiment of the present invention, a plurality of protrusions 110 may be formed on the lower side of the drug liquid chamber 100 , and a plurality of discharge portions 200 may be respectively provided to the plurality of protrusions 110 .

[0133] The protrusion 110 may have a shape in which the diameter decreases as it approaches the skin.

[0134] Therefore, in the present embodiment, as the drug is discharged through the plurality of discharge parts 200 , the drug injection range of the skin can be expanded.

[0135] Fig.15is a cross-sectional view showing a medicine injection device according to a ninth embodiment of the present invention, Fig.16 is a cross-sectional view showing a state in which a medicine is discharged by a medicine injection device according to a ninth embodiment of the present invention.

[0136] like Figure 15 to Figure 16 As shown, unlike the fifth embodiment, the drug injection device according to the ninth embodiment of the present invention may also include: a plunger 1100, a moving coil 1200, a first magnetic coil 1300, a second magnetic coil 1400, a current applying part 1500 for the moving coil, a current applying part 1600 for the first magnetic coil, and a current applying part 1700 for the second magnetic coil.

[0137] The plunger 1100 is provided in the drug liquid chamber 100 so as to be reciprocatable, and approaches the discharge portion to apply pressure to discharge the drug liquid 10 stored in the drug liquid chamber 100 through the discharge portion 200 .

[0138] The plunger 1100 may include a plunger head and a plunger shaft. Here, the plunger head may have an outer diameter corresponding to the inner diameter of the medical fluid chamber 100, and the shaft of the plunger 1100 may have an outer diameter smaller than that of the plunger head.

[0139] The moving coil 1200 may be provided in the plunger 1100. The moving coil 1200 may be moved toward the discharge portion 200 by the magnetic force generated between the first magnetic coil 1300 and the moving coil 1200, and may be moved away from the discharge portion 200 by the magnetic force generated between the second magnetic coil 1400 and the moving coil 1200, and the details of this will be described later. The moving coil 1200 may receive a pulse current from the moving coil current applying unit 1500 described later to generate a magnetic force.

[0140] The first magnetic coil 1300 may be provided at one side of the drug liquid chamber 100, and apply a magnetic force to move the moving coil 1200 close to the discharge portion 200. For example, the first magnetic coil 1300 may be provided at the upper end of the drug liquid chamber 100 where the discharge portion 200 is not provided, and the moving coil 1200 may be provided between the first magnetic coil 1300 and the discharge portion 200.

[0141] In one embodiment, if the moving coil 1200 and the first magnetic coil 1300 receive a pulse current, the moving coil 1200 and the first magnetic coil 1300 may have magnetic forces of the same polarity. Therefore, if magnetic forces are simultaneously formed in the moving coil 1200 and the first magnetic coil 1300, as a repulsive force is generated between the moving coil 1200 and the first magnetic coil 1300, the moving coil 1200 and the plunger 1100 may move in a direction close to the drug liquid chamber 100.

[0142] The second magnetic coil 1400 may be provided at the other side of the drug liquid chamber 100, and may apply a magnetic force to separate the moving coil 1200 from the discharge portion 200. For example, the second magnetic coil 1400 may be provided at the lower end portion of the drug liquid chamber 100 where the discharge portion 200 is located, and the moving coil 1200 may be provided between the first magnetic coil 1300 and the second magnetic coil 1400.

[0143] In one embodiment, if the moving coil 1200 and the second magnetic coil 1400 receive a pulse current, the moving coil 1200 and the second magnetic coil 1400 may have magnetic forces of the same polarity. Therefore, if magnetic forces are simultaneously formed in the moving coil 1200 and the second magnetic coil 1400, as a repulsive force is generated between the moving coil 1200 and the second magnetic coil 1400, the moving coil 1200 and the plunger 1100 may move toward a direction close to the drug liquid chamber 100.

[0144] Although not in Figure 15 to Figure 16 , but the ninth embodiment may include the discharge portion 200, the drug liquid storage portion 400, and the check valve 500 of the sixth embodiment. Therefore, if the moving coil 1200 and the plunger 1100 move in a direction close to the drug liquid chamber 100, after the drug liquid is discharged from the drug liquid chamber 100 through the discharge portion 200, the drug liquid 10 stored in the drug liquid storage portion 400 may be injected into the drug liquid storage portion 400 through the check valve 500 by the negative pressure generated in the drug liquid chamber 100.

[0145] The moving coil current applying unit 1500 may be electrically connected to the moving coil 1200 to apply a pulse current to the moving coil 1200 .

[0146] The first magnetic coil current applying unit 1600 may be electrically connected to the first magnetic coil 1300 to apply a pulse current to the first magnetic coil 1300 .

[0147] The second magnetic coil current applying unit 1700 may be electrically connected to the second magnetic coil 1400 to apply a pulse current to the second magnetic coil 1400 .

[0148] Such a moving coil current applying unit 1500 , a first magnetic coil current applying unit 1600 , and a second magnetic coil current applying unit 1700 can apply a pulse current under the control of a control unit.

[0149] Hereinafter, the operation of the medicine injection device according to the ninth embodiment of the present invention will be described. The following process may be performed by the control part 600.

[0150] First, the moving coil current applying unit 1500 and the first magnetic coil current applying unit 1600 simultaneously apply pulse current to the moving coil 1200 and the first magnetic coil 1300 .

[0151] As a result, as a repulsive force is generated between the moving coil 1200 and the first magnetic coil 1300, the moving coil 1200 and the plunger 1100 may move toward the direction approaching the drug liquid chamber 100. At this time, as the plunger 1100 moves toward the direction approaching the discharge portion 200 and applies pressure to discharge the drug liquid stored in the drug liquid chamber 100 to the discharge portion 200, the drug liquid stored in the drug liquid chamber 100 may be discharged through the discharge portion 200.

[0152] Subsequently, the moving coil current applying section 1500 and the second magnetic coil current applying section 1700 simultaneously apply pulse currents to the moving coil 1200 and the second magnetic coil 1400 .

[0153] As a result, as a repulsive force is generated between the moving coil 1200 and the second magnetic coil 1400 , the moving coil 1200 and the plunger 1100 may move in a direction away from the medical fluid chamber 100 .

[0154] According to the present invention, the drug injection device according to an embodiment of the present invention does not require a pressure chamber and an elastic membrane, thereby having an effect of being able to simplify the structure.

[0155] Furthermore, the drug injection device according to an embodiment of the present invention has the following effect: by adjusting the temperature of the drug stored in the drug chamber, the drug injected from the drug chamber into the deep part of the skin can transfer warmth and coldness to the deep part of the skin.

[0156] The embodiments of the present invention are described above with reference to the accompanying drawings, but it is understood by those with ordinary knowledge in the technical field to which the present invention belongs that the present invention can be implemented in other specific forms without changing the technical concept or essential features of the present invention. Therefore, the embodiments described above should be understood to be exemplary in all aspects, rather than restrictive.

Claims

1. A drug injection device, comprising: A medicine liquid chamber for storing medicine liquid; A discharge part, provided in the liquid medicine chamber, for discharging the liquid medicine; as well as a laser supply unit for supplying pulsed laser to the liquid medicine to generate bubbles, The bubbles induce the volume of the drug liquid to expand and then disappear, thereby generating a shock wave that pushes the drug liquid toward the discharge portion.

2. The drug injection device according to claim 1, wherein: The drug solution is a liquid, sol or liquid phase substance that generates the bubbles by the pulse laser.

3. The drug injection device according to claim 1, further comprising: a liquid medicine storage unit for storing liquid medicine to be supplied to the liquid medicine chamber; as well as a check valve to transfer the liquid medicine stored in the liquid medicine storage unit only to the liquid medicine chamber; After the drug liquid is discharged through the discharge portion, the drug liquid stored in the drug liquid storage portion is injected into the drug liquid storage portion through the check valve by the negative pressure generated in the drug liquid chamber.

4. The drug injection device according to claim 3, further comprising: a temperature sensor for measuring the temperature of the liquid medicine stored in the liquid medicine chamber; a flow sensor for measuring the flow rate of the liquid medicine discharged through the discharge portion; a pressure sensor for measuring the pressure of the liquid medicine stored in the liquid medicine chamber; as well as The control unit forces the check valve to open when at least one of the temperature value measured by the temperature sensor, the flow value measured by the flow sensor, and the pressure value measured by the pressure sensor exceeds a set reference value, so that the drug stored in the drug storage unit is supplied to the drug chamber.

5. The drug injection device according to claim 1, wherein: The medical solution includes a filler.

6. The drug injection device according to claim 1, further comprising: The liquid medicine guide is provided at the discharge portion to guide the liquid medicine discharged through the discharge portion to be sprayed in the form of fine particles.

7. The drug injection device according to claim 6, wherein: The drug liquid guide comprises: a guide body, provided at the discharge portion to reduce a cross-sectional area of ​​the discharge portion; and A guide groove is formed in a spiral shape on the outer peripheral surface of the guide body. The liquid medicine discharged through the discharge portion flows along the guide groove while generating a vortex, thereby being sprayed in the form of fine particles.

8. The drug infusion device according to claim 3, further comprising: The temperature adjustment unit heats or cools the drug solution stored in the drug solution chamber so that the temperature of the drug solution stored in the drug solution chamber is maintained at a set temperature.

9. The drug injection device according to claim 8, wherein: The temperature regulating unit comprises: A Peltier element is provided in the liquid medicine chamber to release cold or warm heat; and The current supply unit adjusts the direction of the current applied to the Peltier element according to the set temperature so that the Peltier element releases cold heat or warm heat.

10. The drug injection device according to claim 8, wherein: The drug liquid chamber includes a heat insulating material.

11. The drug infusion device according to claim 8, further comprising: The auxiliary temperature adjustment unit is provided in the drug liquid storage unit to heat or cool the drug liquid stored in the drug liquid chamber so that the temperature of the drug liquid stored in the drug liquid chamber is maintained at a set temperature.

12. The drug injection device according to claim 9, wherein: The temperature regulating unit comprises: an auxiliary Peltier element, provided in the liquid medicine storage portion, to release cold or warm heat; and The auxiliary current supply unit adjusts the direction of the current applied to the auxiliary Peltier element according to the set temperature, so that the auxiliary Peltier element releases cold heat or warm heat.

13. The drug infusion device according to claim 1, further comprising: a plunger, which is reciprocally movably provided in the drug liquid chamber and approaches the discharge portion to apply pressure to discharge the drug liquid stored in the drug liquid chamber through the discharge portion; A moving coil, provided on the plunger; A first magnetic coil is provided at one side of the liquid medicine chamber and applies a magnetic force to make the moving coil approach the discharge portion; as well as The second magnetic coil is disposed on the other side of the drug liquid chamber and applies a magnetic force to separate the moving coil from the discharge portion.

14. The drug infusion device according to claim 13, further comprising: a moving coil current applying unit for applying a pulse current to the moving coil; a first magnetic coil current applying unit for applying a pulse current to the first magnetic coil; as well as The second magnetic coil current applying unit applies a pulse current to the second magnetic coil.

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