Traditional Chinese veterinary medicine for treating diarrhea of newborn livestock as well as preparation process and application of traditional Chinese veterinary medicine

By using Chinese veterinary medicines made of Chinese medicinal materials such as Poria cocos peel, the problems of low survival rates and antibiotic resistance of existing drugs have been solved, and higher survival rates and stronger disease resistance have been achieved, while reducing production costs.

CN119405733APending Publication Date: 2025-02-11HARBIN LVDASHENG ANIMAL PHARM CO LTD
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Patent Information

Application Number
CN202411659958.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-20
Publication Date
2025-02-11

AI Technical Summary

Technical Problem

The survival rate of existing drugs for treating diarrhea in adolescent animals is low, and the resistance to antibiotics increases and the efficacy is reduced.

Method used

Chinese veterinary medicines made of Chinese medicinal materials such as Poria cocos peel, Scutellaria baicalensis, Poplar flower, Schisandra chinensis, Whitehead, White Peony, and Maleola are prepared through decoction and ethanol extraction to form oral preparations or solid granulation.

Benefits of technology

It improves the survival rate of diarrhea in young animals, reduces the irritation and damage of drugs to young animals, enhances the resistance of young animals, and reduces production costs and improves production efficiency.

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Abstract

The invention relates to the technical field of veterinary drugs, and discloses a traditional Chinese veterinary drug for treating diarrhea of newborn livestock and a preparation method and application of the traditional Chinese veterinary drug. The traditional Chinese medicine composition comprises the following components in parts by weight: 10-30 parts of poria cocos peel, 10-30 parts of scutellaria baicalensis, 20-80 parts of poplar flower, 10-60 parts of schisandra chinensis, 5-20 parts of Chinese pulsatilla root, 5-20 parts of white paeony root and 10-30 parts of purslane. According to the traditional Chinese veterinary medicine for treating diarrhea of the newborn livestock and the preparation process and application thereof, the veterinary medicine obtained through the steps is prepared from Chinese herbal medicines, so that stimulation and harm of the medicine to the newborn livestock can be reduced, meanwhile, the aim of preventing diarrhea is achieved according to the characteristics of the Chinese herbal medicines, and therefore the higher survival rate of the newborn livestock is ensured; meanwhile, normal lactation of the newborn livestock is not affected, so that the immunity of the newborn livestock is improved, and the preparation method is simple in steps and easy to operate in the preparation process of the traditional Chinese veterinary medicine, so that the production cost is reduced.
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Description

Technical Field

[0001] The invention relates to the technical field of veterinary medicines, in particular to a traditional Chinese veterinary medicine for treating diarrhea in young livestock, and a preparation process and application thereof. Background Art

[0002] Piglet diarrhea is a global problem that has long plagued the healthy development of the pig industry. The disease is widespread, has no obvious seasonal outbreak, and is highly contagious. When piglets become ill, it often causes slow growth, reduced feed returns, and even death, causing huge economic losses to the pig industry. There is currently no effective vaccine for immunization and prevention of the disease. Drug treatment is still the main means of prevention and treatment, and antibiotics are the preferred drug for its treatment.

[0003] However, with the long-term use of antibiotics in veterinary clinics, drug resistance has continued to increase and its efficacy has significantly decreased. Therefore, based on previous research, Chinese scholars currently use traditional Chinese medicine to treat piglet diarrhea. Traditional Chinese veterinary theory believes that piglet diarrhea is often related to exogenous pathogens, internal injuries from milk and food, and weak spleen and stomach. The relationship between external factors and dampness is the most obvious. In addition, poor feeding and management lead to dysfunction of the spleen and stomach, inability to digest water and grain, and inability to distinguish between clear and turbid, resulting in diarrhea. Piglets mainly have paste-like, yellow, grayish white, and black loose feces, and some show watery diarrhea.

[0004] A Chinese invention patent with authorization announcement number CN104547177B discloses a Chinese veterinary medicine for treating diarrhea in piglets, a preparation method and a use thereof, wherein the Chinese veterinary medicine is a preparation prepared from raw materials in the following weight ratio: 9 parts of dried tangerine peel, 6 parts of nutmeg, 6 parts of terminalia chebula, and 3 parts of piper longum; it is a preparation prepared from water and / or ethanol extracts of each raw material as active ingredients, plus excipients or auxiliary ingredients commonly used in medicines; the preparation is an oral preparation.

[0005] The survival rate of the above-mentioned Chinese veterinary medicine for treating diarrhea in young livestock is only 73.9%, and the survival rate needs to be improved. Summary of the invention

[0006] 1. Technical issues to be solved

[0007] In view of the deficiencies of the prior art, the present invention provides a traditional Chinese veterinary medicine for treating diarrhea in young livestock, and a preparation process and use thereof, which solves the problem of low survival rate of the existing drugs for treating diarrhea in young livestock.

[0008] (II) Technical solution

[0009] To achieve the above object, the present invention provides the following technical solutions:

[0010] A traditional Chinese veterinary medicine for treating diarrhea in young livestock comprises tuckahoe peel, scutellaria baicalensis, poplar flower, schisandra chinensis, pulsatilla scabra, white peony root and purslane root, wherein the tuckahoe peel accounts for 10-30 parts, the scutellaria baicalensis accounts for 10-30 parts, the poplar flower accounts for 20-80 parts, the schisandra chinensis accounts for 10-60 parts, the pulsatilla scabra accounts for 5-20 parts, the white peony root accounts for 5-20 parts and the purslane root accounts for 10-30 parts.

[0011] A preparation process of a traditional Chinese veterinary medicine for treating diarrhea in young livestock comprises the following steps:

[0012] S1. Preparation of veterinary drug raw materials: Poria peel, Scutellaria baicalensis, poplar flower, Schisandra chinensis, Pulsatilla scabra, White peony root, Portulaca oleracea;

[0013] Among them, the veterinary drug of the present invention can be made into liquid or solid according to the needs;

[0014] S2. Wash the raw materials in S1 with clean water 2-3 times to remove dust and impurities adhering to the surface, thereby ensuring the quality of subsequent veterinary drugs;

[0015] S3, decocting the raw materials obtained in S2 three times, with the decocting time being 1.5-2 hours each, to obtain a veterinary drug stock solution;

[0016] S4, filtering the veterinary drug stock solution obtained in S3, and after filtering, mixing the veterinary drug stock solutions obtained by decoction three times;

[0017] S5, add ethanol 6 times the weight of the veterinary drug stock solution, let it stand for 20-24 hours, filter and recover the ethanol after the standing is completed, add pure water to make up to volume, adjust the pH to 5.0-8.0, and then add potassium sorbate;

[0018] S6, filling and sterilizing the veterinary drug obtained in S5 to obtain the veterinary drug stock solution;

[0019] S7. When the veterinary drug concentrate needs to be made into a solid, pure water is replaced with auxiliary materials based on S5, and the amount of auxiliary materials is 5-10 parts. The veterinary drug concentrate is then granulated by spray drying, dried at 60°C to less than 5% moisture, and sieved through a 10-80 mesh sieve for whole granules.

[0020] Preferably, a corresponding amount of preservative can be added in S1 as required to ensure that the prepared veterinary drug will not deteriorate during storage, and the preservative is potassium sorbate.

[0021] Preferably, in S3, 10 times the weight of the raw material is added with clean water during the first decoction, 8 times the weight of the raw material is added with clean water during the second decoction, and 6 times the weight of the raw material is added with clean water during the third decoction.

[0022] Preferably, the 1:1 mentioned in S4 is the weight ratio of the medicinal solution to the medicinal material.

[0023] Preferably, in S2, after the cleaning is completed, the raw materials are dried by a drying device for later use.

[0024] A use of a traditional Chinese veterinary medicine for treating diarrhea in young animals. When the veterinary medicine is used, the veterinary medicine stock solution can be used according to the weight of the young animals, that is, 1 ml of the veterinary medicine stock solution is used for 10 jin, thereby treating diarrhea in young animals.

[0025] (III) Beneficial effects

[0026] Compared with the prior art, the present invention provides a Chinese veterinary medicine for treating diarrhea in young livestock, and its preparation process and use, which have the following beneficial effects:

[0027] 1. The Chinese veterinary medicine obtained through the above steps has the effects of clearing away heat and detoxifying, removing dampness and stopping diseases, and Scutellaria baicalensis is good at clearing heat and drying dampness, purging fire and detoxifying, and is mainly used for damp-heat diarrhea. The combination of the two has stronger dehumidifying and detoxifying effects, and is used in veterinary clinics to treat diarrhea in piglets. The mild properties of traditional Chinese medicine reduce the stimulation and harm of drugs to young animals, and the purpose of preventing diarrhea is achieved according to the characteristics of the Chinese medicinal materials themselves, thereby ensuring a higher survival rate of young animals, and will not affect the normal lactation of young animals, thereby improving the resistance of young animals. The preparation method is simple and easy to operate in the process of making traditional Chinese veterinary medicine, thereby reducing production costs and improving production efficiency.

[0028] 2. The veterinary medicine prepared through the above steps is made of pure Chinese herbal medicine and has almost no harm to young animals. Therefore, in the case of resisting diarrhea, it can also play the role of conditioning and protecting young animals. DETAILED DESCRIPTION

[0029] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0030] A Chinese veterinary medicine for treating diarrhea in young animals, comprising Poria peel, Scutellaria baicalensis, poplar flower, Schisandra chinensis, Pulsatilla scabra, White Peony Root, and Portulaca oleracea.

[0031] The proportion of Poria peel is 10-30 parts, the proportion of Scutellaria baicalensis is 10-30 parts, the proportion of poplar flower is 20-80 parts, the proportion of Schisandra chinensis is 10-60 parts, the proportion of Pulsatilla scabra is 5-20 parts, the proportion of white peony root is 5-20 parts, and the proportion of Portulaca oleracea is 10-30 parts.

[0032] Embodiment 1:

[0033] A preparation process of a traditional Chinese veterinary medicine for treating diarrhea in young livestock comprises the following steps:

[0034] S1. Veterinary drugs are made of the following raw materials: 30 parts of Poria peel, 30 parts of Scutellaria baicalensis, 80 parts of Poplar flower, 60 parts of Schisandra chinensis, 20 parts of Pulsatilla scutellariae, 20 parts of White Peony Root, and 30 parts of Purslane;

[0035] Among them, a corresponding amount of preservative can be added according to demand to ensure that the prepared veterinary drugs will not deteriorate during storage, and the preservative is potassium sorbate;

[0036] Among them, the veterinary drug of the present invention can be made into liquid or solid according to the needs;

[0037] S2. Wash the raw materials in S1 twice with clean water to remove dust and impurities adhering to the surface, thereby ensuring the quality of subsequent veterinary drugs;

[0038] After cleaning, the raw materials are dried by drying equipment for later use;

[0039] S3, decocting the raw materials obtained in S2 three times, each decocting time is 1.5 hours, to obtain a veterinary drug stock solution;

[0040] The first decoction added 10 times the weight of the raw material water, the second decoction added 8 times the weight of the raw material water, and the third decoction added 6 times the weight of the raw material water;

[0041] S4, filtering the veterinary drug stock solution obtained in S3, and after filtering, mixing the veterinary drug stock solutions obtained by decoction three times;

[0042] Among them, 1:1 is the weight ratio of the liquid medicine to the medicinal material;

[0043] S5, add ethanol with a weight of 6 times that of the veterinary drug stock solution, let it stand for 20 hours, filter and recover the ethanol after the standing is completed, add pure water to make up to volume, adjust the pH to 5.0, and then add potassium sorbate;

[0044] S6, filling and sterilizing the veterinary drug obtained in S5 to obtain the veterinary drug stock solution;

[0045] S7. When the veterinary drug stock solution needs to be made into a solid, pure water is replaced with an auxiliary material based on S5, and the amount of the auxiliary material is 5 parts. The veterinary drug stock solution is then used to granulate by spray drying, dried at 60°C to a moisture content of less than 5%, and sieved through a 10-mesh sieve;

[0046] Among them, auxiliary materials are ground rice, bran, etc.

[0047] Among them, when using, the veterinary drug concentrate can be used according to the weight of the young livestock, that is, 1 ml is used for 10 jin.

[0048] The veterinary medicine obtained through the above steps is made of Chinese herbal medicine, so the stimulation and harm of the medicine to young animals can be reduced. At the same time, the purpose of preventing diarrhea can be achieved according to the characteristics of the Chinese herbal medicine itself, thereby ensuring a higher survival rate of young animals, and at the same time will not affect the normal lactation of young animals, thereby improving the resistance of young animals. The preparation method is simple and easy to operate in the process of making Chinese veterinary medicine, thereby reducing production costs and improving production efficiency.

[0049] Embodiment 2:

[0050] A preparation process of a traditional Chinese veterinary medicine for treating diarrhea in young livestock comprises the following steps:

[0051] S1. Veterinary drugs are made of the following raw materials: 10 parts of Poria peel, 10 parts of Scutellaria baicalensis, 20 parts of Poplar flower, 10 parts of Schisandra chinensis, 5 parts of Pulsatilla scutellariae, 5 parts of White Peony Root, and 10 parts of Portulaca oleracea.

[0052] Among them, a corresponding amount of preservative can be added according to demand to ensure that the prepared veterinary drugs will not deteriorate during storage, and the preservative is potassium sorbate;

[0053] Among them, the veterinary drug of the present invention can be made into liquid or solid according to the needs;

[0054] S2. Wash the raw materials in S1 with clean water for 3 times to remove dust and impurities adhering to the surface, thereby ensuring the quality of subsequent veterinary drugs;

[0055] After cleaning, the raw materials are dried by drying equipment for later use;

[0056] S3, decocting the raw materials obtained in S2 three times, each decocting time is 2 hours, to obtain a veterinary drug stock solution;

[0057] The first decoction added 10 times the weight of the raw material water, the second decoction added 8 times the weight of the raw material water, and the third decoction added 6 times the weight of the raw material water;

[0058] S4, filtering the veterinary drug stock solution obtained in S3, and after filtering, mixing the veterinary drug stock solutions obtained by decoction three times;

[0059] Among them, 1:1 is the weight ratio of the liquid medicine to the medicinal material;

[0060] S5, add 6 times the amount of ethanol as the veterinary drug stock solution, let it stand for 20-24 hours, filter and recover the ethanol after the standing is completed, add pure water to make up to volume, adjust the pH to 8.0, and then add potassium sorbate;

[0061] S6, filling and sterilizing the veterinary drug obtained in S5 to obtain the veterinary drug stock solution;

[0062] Among them, when using, the veterinary drug stock solution can be used according to the weight of the young animal, that is, 1 ml for 10 jin;

[0063] The veterinary medicine obtained through the above steps is made of Chinese herbal medicine, so the stimulation and harm of the medicine to young animals can be reduced. At the same time, the purpose of preventing diarrhea can be achieved according to the characteristics of the Chinese herbal medicine itself, thereby ensuring a higher survival rate of young animals, and at the same time will not affect the normal lactation of young animals, thereby improving the resistance of young animals. The preparation method is simple and easy to operate in the process of making Chinese veterinary medicine, thereby reducing production costs and improving production efficiency.

[0064] Embodiment three:

[0065] A preparation process of a traditional Chinese veterinary medicine for treating diarrhea in young livestock comprises the following steps:

[0066] S1. Veterinary drugs are made of the following raw materials: 20 parts of Poria peel, 20 parts of Scutellaria baicalensis, 40 parts of Poplar flower, 30 parts of Schisandra chinensis, 10 parts of Pulsatilla scutellariae, 10 parts of White Peony Root, and 25 parts of Purslane;

[0067] Among them, a corresponding amount of preservative can be added according to demand to ensure that the prepared veterinary drugs will not deteriorate during storage, and the preservative is potassium sorbate;

[0068] Among them, the veterinary drug of the present invention can be made into liquid or solid according to the needs;

[0069] S2. Wash the raw materials in S1 twice with clean water to remove dust and impurities adhering to the surface, thereby ensuring the quality of subsequent veterinary drugs;

[0070] After cleaning, the raw materials are dried by drying equipment for later use;

[0071] S3, decocting the raw materials obtained in S2 three times, each decocting time is 1.8 hours, to obtain a veterinary drug stock solution;

[0072] The first decoction added 10 times the weight of the raw material water, the second decoction added 8 times the weight of the raw material water, and the third decoction added 6 times the weight of the raw material water;

[0073] S4, filtering the veterinary drug stock solution obtained in S3, and after filtering, mixing the veterinary drug stock solutions obtained by decoction three times;

[0074] Among them, 1:1 is the weight ratio of the liquid medicine to the medicinal material;

[0075] S5, add ethanol with a weight of 6 times the amount of the veterinary drug stock solution, let it stand for 22 hours, filter and recover the ethanol after the standing is completed, adjust the pH to 6.0, and then add potassium sorbate;

[0076] S6, filling and sterilizing the veterinary drug obtained in S5 to obtain the veterinary drug stock solution;

[0077] S7. When the veterinary drug concentrate needs to be made into a solid, pure water is replaced with an auxiliary material based on S5, and the amount of the auxiliary material is 6 parts. The veterinary drug concentrate is then used to prepare granules by spray drying, dried at 60°C to a moisture content of less than 5%, and sieved through a 40-mesh sieve.

[0078] Among them, the auxiliary materials are ground rice, bran, etc.;

[0079] Among them, when using, the veterinary drug stock solution can be used according to the weight of the young animal, that is, 1 ml for 10 jin;

[0080] The veterinary medicine obtained through the above steps is made of Chinese herbal medicine, so the stimulation and harm of the medicine to young animals can be reduced. At the same time, the purpose of preventing diarrhea can be achieved according to the characteristics of the Chinese herbal medicine itself, thereby ensuring a higher survival rate of young animals, and at the same time will not affect the normal lactation of young animals, thereby improving the resistance of young animals. The preparation method is simple and easy to operate in the process of making Chinese veterinary medicine, thereby reducing production costs and improving production efficiency.

[0081] Embodiment 4:

[0082] A preparation process of a traditional Chinese veterinary medicine for treating diarrhea in young livestock comprises the following steps:

[0083] S1. Veterinary drugs are made of the following raw materials: 30 parts of Poria peel, 30 parts of Scutellaria baicalensis, 80 parts of Poplar flower, 10 parts of Schisandra chinensis, 5 parts of Pulsatilla scutellariae, 5 parts of White Peony Root, and 15 parts of Portulaca oleracea.

[0084] Among them, a corresponding amount of preservative can be added according to demand to ensure that the prepared veterinary drugs will not deteriorate during storage, and the preservative is potassium sorbate;

[0085] Among them, the veterinary drug of the present invention can be made into liquid or solid according to the needs;

[0086] S2. Wash the raw materials in S1 with clean water for 3 times to remove dust and impurities adhering to the surface, thereby ensuring the quality of subsequent veterinary drugs;

[0087] After cleaning, the raw materials are dried by drying equipment for later use;

[0088] S3, decocting the raw materials obtained in S2 three times, each decocting time is 1.9 hours, to obtain a veterinary drug stock solution;

[0089] The first decoction added 10 times the weight of the raw material water, the second decoction added 8 times the weight of the raw material water, and the third decoction added 6 times the weight of the raw material water;

[0090] S4, filtering the veterinary drug stock solution obtained in S3, and after filtering, mixing the veterinary drug stock solutions obtained by decoction three times;

[0091] Among them, 1:1 is the weight ratio of the liquid medicine to the medicinal material;

[0092] S5, add 6 times the amount of ethanol of the veterinary drug stock solution, let it stand for 23 hours, filter and recover the ethanol after the standing is completed, adjust the pH to 7.0, and then add potassium sorbate;

[0093] S6, filling and sterilizing the veterinary drug obtained in S5 to obtain the veterinary drug stock solution;

[0094] S7. When the veterinary drug concentrate needs to be made into a solid, pure water is replaced with an auxiliary material based on S5, and the amount of the auxiliary material is 8 parts. The veterinary drug concentrate is then used to prepare granules by spray drying, dried at 60°C to a moisture content of less than 5%, and sieved through a 60-mesh sieve.

[0095] Among them, the auxiliary materials are ground rice, bran, etc.;

[0096] Among them, when using, the veterinary drug stock solution can be used according to the weight of the young animal, that is, 1 ml for 10 jin;

[0097] The veterinary medicine obtained through the above steps is made of Chinese herbal medicine, so the stimulation and harm of the medicine to young animals can be reduced. At the same time, the purpose of preventing diarrhea can be achieved according to the characteristics of the Chinese herbal medicine itself, thereby ensuring a higher survival rate of young animals, and at the same time will not affect the normal lactation of young animals, thereby improving the resistance of young animals. The preparation method is simple and easy to operate in the process of making Chinese veterinary medicine, thereby reducing production costs and improving production efficiency.

[0098] Embodiment five:

[0099] A preparation process of a traditional Chinese veterinary medicine for treating diarrhea in young livestock comprises the following steps:

[0100] S1. Veterinary drugs are made of the following raw materials: 10 parts of Poria peel, 10 parts of Scutellaria baicalensis, 20 parts of Poplar flower, 60 parts of Schisandra chinensis, 20 parts of Pulsatilla scutellariae, 20 parts of White Peony Root, and 30 parts of Portulaca oleracea.

[0101] Among them, a corresponding amount of preservative can be added according to demand to ensure that the prepared veterinary drugs will not deteriorate during storage, and the preservative is potassium sorbate;

[0102] Among them, the veterinary drug of the present invention can be made into liquid or solid according to the needs;

[0103] S2. Wash the raw materials in S1 twice with clean water to remove dust and impurities adhering to the surface, thereby ensuring the quality of subsequent veterinary drugs;

[0104] After cleaning, the raw materials are dried by drying equipment for later use;

[0105] S3, decocting the raw materials obtained in S2 three times, each decocting time is 1.6 hours, to obtain a veterinary drug stock solution;

[0106] The first decoction added 10 times the weight of the raw material water, the second decoction added 8 times the weight of the raw material water, and the third decoction added 6 times the weight of the raw material water;

[0107] S4, filtering the veterinary drug stock solution obtained in S3, and after filtering, mixing the veterinary drug stock solutions obtained by decoction three times;

[0108] Among them, 1:1 is the weight ratio of the liquid medicine to the medicinal material;

[0109] S5, add ethanol 6 times the weight of the veterinary drug stock solution, let it stand for 21 hours, filter and recover the ethanol after the standing is completed, add pure water to make up to volume, adjust the pH to 7.5, and then add potassium sorbate;

[0110] S6, filling and sterilizing the veterinary drug obtained in S5 to obtain the veterinary drug stock solution;

[0111] S7. When the veterinary drug stock solution needs to be made into a solid, pure water is replaced with an auxiliary material based on S5, and the amount of the auxiliary material is 9 parts. The veterinary drug stock solution is then used for granulation by spray drying, dried at 60°C to a moisture content of less than 5%, and sieved with a 70-mesh sieve;

[0112] Among them, the auxiliary materials are ground rice, bran, etc.;

[0113] Among them, when using, the veterinary drug stock solution can be used according to the weight of the young animal, that is, 1 ml for 10 jin;

[0114] The veterinary medicine obtained through the above steps is made of Chinese herbal medicine, so the stimulation and harm of the medicine to young animals can be reduced. At the same time, the purpose of preventing diarrhea can be achieved according to the characteristics of the Chinese herbal medicine itself, thereby ensuring a higher survival rate of young animals, and at the same time will not affect the normal lactation of young animals, thereby improving the resistance of young animals. The preparation method is simple and easy to operate in the process of making Chinese veterinary medicine, thereby reducing production costs and improving production efficiency.

[0115] The following table shows the usage data of veterinary raw materials in the specific processing of the present invention:

[0116]

[0117] A use of a traditional Chinese veterinary medicine for treating diarrhea in young animals: When using the traditional Chinese veterinary medicine, the veterinary medicine concentrate can be used according to the weight of the young animals, that is, 1 ml is used for 10 jin, so as to treat diarrhea in young animals.

[0118] Through clinical verification in 7 large-scale pig farms, vomiting and diarrhea were found and 3 ml / head was immediately administered twice a day for 2 consecutive days. Pig farms with high mortality rate of suckling piglets and diarrhea and PEDV positive were selected, and 5 litters were kept in each farm as controls;

[0119] Control group 1: Oral administration of 2% norfloxacin nicotinic acid oral solution 3 ml / head, twice a day, for 2 consecutive days;

[0120] Control group 2: the Chinese veterinary medicine prepared in Example 1 disclosed in the Chinese invention patent with authorization announcement number CN104547177B, 5 ml / head, twice a day, for 2 consecutive days;

[0121] The remaining diarrhea piglets were experimental groups 1-5, and were gavaged with 5 ml of the Chinese veterinary medicine prepared in the above examples 1-5, twice a day, for 2 consecutive days;

[0122] The number of diarrheal patients in the test group and the experimental group was counted. After 3 days of treatment, the number of cured patients and the number of effective patients were counted on the 5th day.

[0123] Judgment criteria: Cured: The piglet has formed stools, is in good spirits, suckles normally, has clean and smooth fur, and has a locked anus.

[0124] Significantly effective: The piglets’ stools are thick and paste-like, their spirits tend to be normal, they can suckle, their fur is clean, and there is no obvious stool adhesion around the anus.

[0125] Ineffective: The piglets have porridge-like stools, are emaciated, listless or dehydrated, have dirty areas around the anus, and have a loose and red anus.

[0126] Death: All piglets that died from the start of treatment to the 5th day or were unable to suckle were counted as dead.

[0127] Number of heads cure Significant effect invalid die Control group 1 500 235 132 88 45 Control group 2 500 289 112 65 34 Experimental Group 1 500 338 118 32 12 Experimental Group 2 500 340 121 28 11 Experimental Group 3 500 348 109 30 13 Experimental Group 4 500 341 123 26 10 Experimental Group 5 500 345 115 29 11

[0128] The present invention has been tested to show that the cure rate is significantly higher than the existing Chinese veterinary medicine and Western medicine treatment effects, and the pure Chinese medicine production of the present invention can reduce the damage of the medicine to piglets, ensuring that the piglets will not suffer from loss of appetite and mental depression due to the influence of the medicine after being cured. At the same time, the medicinal properties of Chinese medicine can improve the immunity of piglets, and the production steps are simple and easy to operate, thereby reducing production costs.

[0129] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A Chinese veterinary medicine for treating diarrhea in young livestock, characterized in that: The invention is prepared from the following raw materials in proportion by weight: 10-30 parts of Poria peel, 10-30 parts of Scutellaria baicalensis, 20-80 parts of poplar flower, 10-60 parts of Schisandra chinensis, 5-20 parts of Pulsatilla scutellariae, 5-20 parts of White Peony Root and 10-30 parts of Portulaca oleracea.

2. A Chinese veterinary medicine for treating diarrhea in young livestock according to claim 1, characterized in that: The invention is prepared from the following raw materials in the following weight proportions: 10 parts of Poria peel, 10 parts of Scutellaria baicalensis, 20 parts of Poplar flower, 60 parts of Schisandra chinensis, 20 parts of Pulsatilla scutellariae, 20 parts of White Peony Root, and 30 parts of Portulaca oleracea.

3. A Chinese veterinary medicine for treating diarrhea in young livestock according to claim 1, characterized in that: The medicine is prepared from the following raw materials in proportion by weight: 30 parts of Poria peel, 30 parts of Scutellaria baicalensis, 80 parts of poplar flower, 10 parts of Schisandra chinensis, 5 parts of Pulsatilla scutellariae, 5 parts of White Peony Root and 15 parts of Portulaca oleracea.

4. A Chinese veterinary medicine for treating diarrhea in young livestock according to claim 1, characterized in that: The medicine is prepared from the following raw materials in the following weight proportions: 20 parts of Poria peel, 20 parts of Scutellaria baicalensis, 40 parts of poplar flower, 30 parts of Schisandra chinensis, 10 parts of Pulsatilla scutellariae, 10 parts of White Peony Root and 25 parts of Portulaca oleracea.

5. A preparation process of a Chinese veterinary medicine for treating diarrhea in young livestock according to any one of claims 1 to 4, characterized in that: The following steps are involved: S1. Preparation of veterinary drug raw materials: Poria peel, Scutellaria baicalensis, poplar flower, Schisandra chinensis, Pulsatilla scabra, White peony root, Portulaca oleracea; S2. Wash the raw materials in S1 with clean water 2-3 times to remove dust and impurities adhering to the surface; S3, decocting the raw materials obtained in S2 three times, with the decocting time being 1.5-2 hours each, to obtain a veterinary drug stock solution; S4, filtering the veterinary drug stock solution obtained in S3, and after filtering, mixing the veterinary drug stock solutions obtained by three decoctions; S5, add 6 times the amount of ethanol of the veterinary drug stock solution, let it stand for 20-24 hours, filter and recover the ethanol after the standing is completed, add pure water to make up to volume, adjust the pH to 5.0-8.0, and then add potassium sorbate; S6. Fill and sterilize the veterinary medicine obtained in S5 to obtain the Chinese veterinary medicine concentrate.

6. The process for preparing a Chinese veterinary medicine for treating diarrhea in young livestock according to claim 5, characterized in that: In S1, a corresponding amount of preservative can be added as required to ensure that the prepared veterinary drug will not deteriorate during storage, and the preservative is potassium sorbate.

7. The preparation process of a Chinese veterinary medicine for treating diarrhea in young livestock according to claim 5, characterized in that: In S3, 10 times the amount of clean water is added to the raw material for the first decoction, 8 times the weight of the raw material is added to the second decoction, and 6 times the weight of the raw material is added to the third decoction.

8. The process for preparing a Chinese veterinary medicine for treating diarrhea in young livestock according to claim 5, characterized in that: The 1:1 mentioned in S4 is the weight ratio of the medicinal solution to the medicinal material.

9. The process for preparing a Chinese veterinary medicine for treating diarrhea in young livestock according to claim 5, characterized in that: In S2, after the cleaning is completed, the raw materials are dried by a drying device for later use.

10. A use of a traditional Chinese veterinary medicine for treating diarrhea in young animals according to any one of claims 1 to 4, characterized in that: When the veterinary drug is used, the veterinary drug stock solution can be used according to the weight of the young animals to treat diarrhea in the young animals.

Citation Information

Patent Citations

  • A traditional Chinese veterinary medicine for treating diarrhea in piglets, its preparation method and uses

    CN104547177B