Preparation process and method for extracting chlorogenic acid from folium cortex eucommiae

Abstract

The invention relates to the technical field of extraction of chlorogenic acid from folium cortex eucommiae, and discloses a preparation process and method for extracting chlorogenic acid from folium cortex eucommiae, a preparation cylinder is included, an extraction filtering mechanism is arranged in the preparation cylinder, an additional filtering plate assembly is arranged on one side of the extraction filtering mechanism, and a cover plate is movably connected to the top end of the preparation cylinder. Through the arrangement of the extracting and filtering mechanism, the effect of conveniently extracting and filtering chlorogenic acid in folium cortex eucommiae can be achieved, in the using process, auxiliary fixing and further pressurized extraction of an extracted product are completed through a filter plate and a pressing plate, then the extracted product is placed in water to be soaked and extracted, then the filter plate is pulled up through a pull rod, and then the extracted product is taken out through the pull rod. The filter plate is used for filtering the eucommia ulmoides leaf particles and the extracting solution, so that the situation that a plurality of devices are needed to complete extraction and filtration as the traditional preparation equipment needs to perform extraction and then perform filtration can be avoided, the integrity of the preparation equipment is ensured, and the preparation equipment is more practical to use.

Description

Technical Field

[0001] The invention relates to the technical field of extracting chlorogenic acid from eucommia leaves, and specifically to a preparation process and a method for extracting chlorogenic acid from eucommia leaves. Background Art

[0002] Chlorogenic acid in Eucommia leaves is one of its main active ingredients. Chlorogenic acid exists naturally in Eucommia leaves and plays a certain role in the physiological activities of Eucommia. From the chemical structure point of view, it is an ester formed by caffeic acid and quinic acid. Chlorogenic acid in Eucommia leaves also has multiple biological activities such as antioxidant and anti-inflammatory. It occupies an important position in the medicinal and health-care value of Eucommia, and may have a series of potential positive effects on human health. At the same time, the content of chlorogenic acid is often used as an important indicator for evaluating the quality of Eucommia leaves.

[0003] In the prior art, patent number CN 218306295 U is a kind of ultrasonic extraction equipment for preparing ganoderma lucidum polysaccharide, which belongs to the technical field of beauty cosmetics production equipment. The equipment includes a box, an isolation screen, a water spray pipe, a pressure pump and an ultrasonic extractor. When adding ganoderma lucidum powder and water for ultrasonic extraction, the pressure pump is started, and the ganoderma lucidum powder on the isolation screen is sprayed with normal temperature or low temperature water through the water spray pipe, so that the ganoderma lucidum powder accumulated at the bottom moves upward. After multiple spraying, the negative effect of ganoderma lucidum powder accumulation on ultrasonic extraction can be reduced. At the same time, the spraying of normal temperature water or low temperature water can reduce the degradation effect of the thermal effect of ultrasonic extraction on ganoderma lucidum polysaccharide. The extraction equipment solves the problem of insufficient extraction.

[0004] Although the above invention patent solves the problem of insufficient extraction, most of the preparation equipment currently used is not convenient for extracting and filtering chlorogenic acid. During use, traditional preparation equipment needs to extract chlorogenic acid first and then filter. The preparation process is relatively complicated and requires more procedures and multiple equipment for preparation, which makes the practicality of the preparation equipment poor and inconvenient to disassemble the filter plate and the fixing ring. During use, if the filter plate cannot be removed, the residue filtered on the filter plate may be difficult to remove. If the filter plate is not cleaned for a long time, it may cause the Eucommia leaf residue on the filter plate to accumulate and clog, thereby making the filter plate unable to perform normal filtering work, which makes the practicality of the preparation equipment poor. Summary of the invention

[0005] The present invention provides a preparation process and method for extracting chlorogenic acid from eucommia leaves, which solves the problems raised by a preparation process and method for extracting chlorogenic acid from eucommia leaves in the related art.

[0006] The technical solution of the present invention is as follows:

[0007] A preparation process for extracting chlorogenic acid from eucommia leaves, using a preparation device for extracting chlorogenic acid from eucommia leaves, the device comprising a preparation cylinder, an extraction and filtering mechanism is arranged inside the preparation cylinder, an additional filter plate assembly is arranged on one side of the extraction and filtering mechanism, a cover plate is movably connected to the top of the preparation cylinder, a handle is fixedly connected to the top of the cover plate, a pipe is fixedly connected to the outer wall of the preparation cylinder, a water pump is fixedly connected to the outer wall of the pipe, and a heating element is fixedly connected to the outer wall of the preparation cylinder.

[0008] Preferably, the extraction and filtration mechanism includes a retaining ring, the number of which is two, and the two retaining rings are symmetrically arranged with the vertical midline of the preparation cylinder as the symmetry axis, and a filter plate is attached to the top of the retaining ring, and the retaining ring can clamp the filter plate to the inner wall of the preparation cylinder.

[0009] Preferably, a fixing ring is movably connected to the top of the filter plate, and a vertical center line of the fixing ring coincides with a vertical center line of the filter plate.

[0010] Preferably, a pull rod is fixedly connected to the top of the filter plate, and a vertical center line of the pull rod coincides with a vertical center line of the filter plate.

[0011] Preferably, a fixing ring is movably connected to the top of the filter plate, and a vertical center line of the fixing ring coincides with a vertical center line of the filter plate.

[0012] Preferably, the outer wall of the fixing ring is fixedly connected to a support frame, and the bottom of the support frame is fixedly connected to an electric push rod.

[0013] Preferably, a pressing plate is fixedly connected to the bottom end of the electric push rod, and a vertical center line of the pressing plate coincides with a vertical center line of the fixing ring.

[0014] Preferably, the outer wall of the fixing ring is provided with an additional filter plate assembly, and the additional filter plate assembly includes a mounting plate. The outer wall of the fixing ring is fixedly connected with the mounting plate. There are two mounting plates, and the two mounting plates are symmetrically arranged with the vertical center line of the fixing ring as the axis of symmetry.

[0015] Preferably, the top of the mounting plate and the top of the filter plate are both provided with through holes, and the inner walls of the through holes are movably connected with bolts;

[0016] The shape and size of the bolt match the shape and size of the through hole, and a nut is threadedly connected to the outer wall of the bolt.

[0017] A method for preparing a preparation device for extracting chlorogenic acid from eucommia leaves comprises the following steps:

[0018] Step S1: Open the cover plate by the handle, and then pull the pull rod, which drives the remaining components of the extraction and filtration mechanism and the additional filter plate assembly to rise synchronously, and pull up the filter plate;

[0019] Step S2: placing the crushed Eucommia leaf particles into the fixing ring, and then starting the electric push rod to make the electric push rod start to extend, and the electric push rod drives the pressing plate to start to descend, so that the pressing plate fixes the Eucommia leaf particles and squeezes the Eucommia leaf through the pressing plate;

[0020] Step S3: placing the filter plate on the clamping ring and fixing it by a pull rod;

[0021] Step S4: Pour the prepared 70% ethanol into the preparation cylinder, and then start the heating element. At this time, start the electric push rod in reverse to make the pressing plate break away from the control of the Eucommia leaf particles, so that the chlorogenic acid in the Eucommia leaf is dissolved in the 70% ethanol, thereby completing the extraction work;

[0022] Step S5: Open the cover plate by a handle, pull the pull rod, and pull the filter plate out of the preparation cylinder. When the filter plate is pulled out upward, impurities in the water and the residue of the Eucommia leaf particles can be filtered onto the filter plate and pulled out together with the filter plate;

[0023] Step S6: The water pump discharges the extract in the preparation tube out of the preparation tube through the pipeline, and the extract is collected by the container for later use;

[0024] Step S7: recovering ethanol from the extract at 50-60° C. under reduced pressure until there is no alcohol taste, and extracting again to obtain an extract;

[0025] Step S8: After adding activated carbon to the extract, boiling and filtering to obtain a filtrate, the filtrate is spray-dried and cyclone-dried to obtain chlorogenic acid powder.

[0026] The working principle and beneficial effects of the present invention are:

[0027] 1. The extraction and filtration mechanism of the present invention can facilitate the extraction and filtration of chlorogenic acid in Eucommia ulmoides leaves. During use, the filter plate and the pressing plate are used to auxiliary fix the extract and further pressurized extraction, and then the extract is placed in water for immersion extraction. The filter plate is then pulled up by a pull rod to filter the Eucommia ulmoides leaf particles and the extract. This can avoid the situation where multiple devices are required to complete the extraction and filtration because traditional preparation equipment needs to extract first and then filter, thereby ensuring the integrity of the preparation equipment and making the preparation equipment more practical to use.

[0028] 2. The additional filter plate assembly of the present invention can facilitate the disassembly of the filter plate and the fixing ring. During use, the filter plate and the fixing ring can be disassembled by rotating the nut out of the bolt, thereby avoiding the difficulty in removing the filtered residue on the filter plate due to the inability to remove the filter plate. If the filter plate is not cleaned for a long time, the eucommia leaf residue on the filter plate will accumulate and clog the filter plate, making it impossible for the filter plate to perform normal filtering work, thereby ensuring the practicability of the preparation equipment. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0030] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;

[0031] Figure 2 It is a cross-sectional view of the internal structure of the preparation tube of the present invention;

[0032] Figure 3 It is a schematic diagram of the connection structure between the filter plate and the clamp ring of the present invention;

[0033] Figure 4 It is a schematic diagram of the structure of the extraction and filtration mechanism of the present invention;

[0034] Figure 5 It is a schematic diagram of the structure of the additional filter plate assembly of the present invention;

[0035] Figure 6 It is a schematic diagram of the through hole structure opened on the mounting plate and the filter plate of the present invention.

[0036] In the figure:

[0037] 1. Prepare the cylinder;

[0038] 2. Extraction and filtration mechanism; 201. Clamp ring; 202. Filter plate; 203. Fixing ring; 204. Pull rod; 205. Support frame; 206. Electric push rod; 207. Press plate;

[0039] 3. Additional filter plate assembly; 301. Mounting plate; 302. Through hole; 303. Bolt; 304. Nut;

[0040] 4. Cover; 5. Handle; 6. Pipe; 7. Water pump; 8. Heating element. DETAILED DESCRIPTION

[0041] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0042] Example 1

[0043] like Figure 1 and Figure 2 As shown, a preparation process and method for extracting chlorogenic acid from eucommia leaves include a preparation barrel 1, an extraction and filtering mechanism 2 is arranged inside the preparation barrel 1, an additional filter plate assembly 3 is arranged on one side of the extraction and filtering mechanism 2, a cover plate 4 is movably connected to the top of the preparation barrel 1, a handle 5 is fixedly connected to the top of the cover plate 4, a pipe 6 is fixedly connected to the outer wall of the preparation barrel 1, a water pump 7 is fixedly connected to the outer wall of the pipe 6, and a heating element 8 is fixedly connected to the outer wall of the preparation barrel 1.

[0044] In this embodiment, when the preparation equipment is needed to prepare chlorogenic acid in Eucommia leaves, the cover plate 4 is first opened by the handle 5, and the chlorogenic acid in the Eucommia leaves is extracted by the set extraction and filtering mechanism 2. During the extraction process, the hot water in the preparation cylinder 1 is kept at a constant temperature by starting the heating element 8, so that the chlorogenic acid in the Eucommia leaves is dissolved into the hot water by immersion in the hot water, thereby completing the extraction work, and then the residue and the extract are filtered by the set extraction and filtering mechanism 2 to complete the work. When the work is completed, the filter plate 202 needs to be disassembled and separated from the fixing ring 203 to facilitate the cleaning of the filter plate 202, and the additional filter plate assembly 3 is provided to disassemble and complete the work.

[0045] Example 2

[0046] like Figure 1 , Figure 2 , Figure 3 and Figure 4As shown, based on the same concept as the above-mentioned embodiment 1, this embodiment further proposes an extraction and filtration mechanism 2, which includes a clamping ring 201. The number of the clamping rings 201 is two, and the two clamping rings 201 are symmetrically arranged with the vertical midline of the preparation tube 1 as the symmetry axis. The top of the clamping ring 201 is attached with a filter plate 202, and the clamping ring 201 can clamp the filter plate 202 on the inner wall of the preparation tube 1. The top of the filter plate 202 is movably connected with a fixing ring 203, and the vertical axis of the fixing ring 203 is symmetrical. The straight center line coincides with the vertical center line of the filter plate 202, a pull rod 204 is fixedly connected to the top of the filter plate 202, the vertical center line of the pull rod 204 coincides with the vertical center line of the filter plate 202, the outer wall of the fixed ring 203 is fixedly connected to a support frame 205, the bottom of the support frame 205 is fixedly connected to an electric push rod 206, the bottom end of the electric push rod 206 is fixedly connected to a pressure plate 207, the vertical center line of the pressure plate 207 coincides with the vertical center line of the fixed ring 203.

[0047] In this embodiment, when the preparation equipment is needed to prepare chlorogenic acid in Eucommia ulmoides leaves, the cover plate 4 is first opened by the handle 5, and then the pull rod 204 is pulled, and the pull rod 204 drives the remaining components of the extraction and filtration mechanism 2 and the additional filter plate assembly 3 to rise synchronously, and the filter plate 202 is pulled up, and then the crushed Eucommia ulmoides leaf particles are placed in the fixing ring 203, and then the electric push rod 206 is started, so that the electric push rod 206 begins to extend, and the electric push rod 206 drives the pressing plate 207 to begin to descend, so that the pressing plate 207 fixes the Eucommia ulmoides leaf particles, and the pressing plate 207 squeezes the Eucommia ulmoides leaves, so that the effective ingredients in the Eucommia ulmoides leaves can be released faster and better, and then the filter plate 202 is placed on the clamping ring 201 and fixed by the pull rod 204, and then the well-proportioned Pour the hot water into the preparation cylinder 1, and then start the heating element 8 to keep the hot water in the preparation cylinder 1 at a constant temperature. At this time, start the electric push rod 206 in reverse to make the pressure plate 207 break away from the control of the Eucommia leaf particles, so that the chlorogenic acid in the Eucommia leaves is dissolved into the hot water through hot water immersion, thereby completing the extraction work, and then open the cover plate 4 through the handle 5, pull the pull rod 204, and pull the filter plate 202 out of the preparation cylinder 1. When the filter plate 202 is pulled out upward, the impurities in the water and the residue of the Eucommia leaf particles can be filtered onto the filter plate 202 and pulled out together with the filter plate 202. Then start the water pump 7, and the water pump 7 discharges the extract in the preparation cylinder 1 out of the preparation cylinder 1 through the pipe 6, and the extract is received by the container, thereby completing the preparation work.

[0048] like Figure 2 , Figure 5 and Figure 6As shown, based on the same concept as the above-mentioned embodiment 1, this embodiment further proposes an additional filter plate assembly 3, which includes a mounting plate 301, and the outer wall of the fixing ring 203 is fixedly connected with the mounting plate 301. The number of the mounting plates 301 is two, and the two mounting plates 301 are symmetrically arranged with the vertical center line of the fixing ring 203 as the symmetry axis. The top of the mounting plate 301 and the top of the filter plate 202 are both provided with a through hole 302, and the inner wall of the through hole 302 is movably connected with a bolt 303, the shape and size of the bolt 303 match the shape and size of the through hole 302, and the outer wall of the bolt 303 is threadedly connected with a nut 304.

[0049] In this embodiment, when the work is completed, the filter plate 202 needs to be disassembled and separated from the fixing ring 203 to facilitate cleaning of the filter plate 202. At this time, the nut 304 is rotated to rotate the nut 304 out of the outer wall of the bolt 303, and then the bolt 303 is taken out from the through hole 302 opened on the mounting plate 301 and the through hole 302 opened on the filter plate 202, and then the fixing ring 203 can be disassembled and separated from the filter plate 202 to facilitate cleaning of the filter plate 202, thereby completing the disassembly and cleaning work.

[0050] Example 3

[0051] In combination with Examples 1 and 2, further, Figure 1-6 As shown, a method for preparing a preparation device for extracting chlorogenic acid from Eucommia ulmoides leaves comprises the following steps:

[0052] Step S1: Open the cover plate 4 through the handle 5, and then pull the pull rod 204, the pull rod 204 drives the other components of the extraction and filtration mechanism 2 and the additional filter plate assembly 3 to rise synchronously, and pull up the filter plate 202;

[0053] Step S2: placing the crushed Eucommia leaf particles into the fixing ring 203, and then starting the electric push rod 206, so that the electric push rod 206 begins to extend, and the electric push rod 206 drives the pressing plate 207 to begin to descend, so that the pressing plate 207 fixes the Eucommia leaf particles, and the Eucommia leaf is squeezed by the pressing plate 207;

[0054] Step S3: placing the filter plate 202 on the clamping ring 201 and fixing it by the pull rod 204;

[0055] Step S4: pour the prepared 70% ethanol into the preparation cylinder 1, and then start the heating element 8, and then start the electric push rod 206 in reverse, so that the pressing plate 207 is released from the control of the Eucommia leaf particles, so that the chlorogenic acid in the Eucommia leaf is dissolved in the 70% ethanol through immersion in 70% ethanol, thereby completing the extraction work;

[0056] Step S5: Open the cover plate 4 by the handle 5, pull the pull rod 204, and pull the filter plate out of the preparation cylinder 1. When the filter plate 202 is pulled out upward, the impurities in the water and the residue of the Eucommia leaf particles can be filtered onto the filter plate 202 and pulled out together with the filter plate 202;

[0057] Step S6: the water pump 7 discharges the extract in the preparation tube 1 out of the preparation tube 1 through the pipeline 6, and the extract is collected by a container for later use;

[0058] Step S7: recovering ethanol from the extract at 50-60° C. under reduced pressure until there is no alcohol taste, and extracting again to obtain an extract;

[0059] Step S8: After adding activated carbon to the extract, boiling and filtering to obtain a filtrate, the filtrate is spray-dried and cyclone-dried to obtain chlorogenic acid powder.

[0060] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A preparation process for extracting chlorogenic acid from Eucommia ulmoides leaves, characterized in that , a preparation device for extracting chlorogenic acid from Eucommia ulmoides leaves is used, the device comprising a preparation cylinder (1), an extraction and filtering mechanism (2) is arranged inside the preparation cylinder (1), an additional filter plate assembly (3) is arranged on one side of the extraction and filtering mechanism (2), a cover plate (4) is movably connected to the top of the preparation cylinder (1), a handle (5) is fixedly connected to the top of the cover plate (4), a pipe (6) is fixedly connected to the outer wall of the preparation cylinder (1), a water pump (7) is fixedly connected to the outer wall of the pipe (6), and a heating element (8) is fixedly connected to the outer wall of the preparation cylinder (1).

2. The preparation equipment for extracting chlorogenic acid from Eucommia ulmoides leaves according to claim 1, characterized in that: The extraction and filtering mechanism (2) comprises a clamping ring (201), the number of the clamping rings (201) is two, and the two clamping rings (201) are symmetrically arranged with the vertical center line of the preparation barrel (1) as the symmetry axis, and the top of the clamping ring (201) is attached with a filter plate (202), and the clamping ring (201) can clamp the filter plate (202) on the inner wall of the preparation barrel (1).

3. The preparation equipment for extracting chlorogenic acid from Eucommia ulmoides leaves according to claim 2, characterized in that: A fixing ring (203) is movably connected to the top of the filter plate (202), and the vertical center line of the fixing ring (203) coincides with the vertical center line of the filter plate (202).

4. The preparation equipment for extracting chlorogenic acid from Eucommia ulmoides leaves according to claim 3, characterized in that: A pull rod (204) is fixedly connected to the top of the filter plate (202), and a vertical center line of the pull rod (204) coincides with a vertical center line of the filter plate (202).

5. The preparation equipment for extracting chlorogenic acid from Eucommia ulmoides leaves according to claim 2, characterized in that: A fixing ring (203) is movably connected to the top of the filter plate (202), and the vertical center line of the fixing ring (203) coincides with the vertical center line of the filter plate (202).

6. The preparation equipment for extracting chlorogenic acid from Eucommia ulmoides leaves according to claim 4, characterized in that: The outer wall of the fixing ring (203) is fixedly connected to a support frame (205), and the bottom of the support frame (205) is fixedly connected to an electric push rod (206).

7. The preparation equipment for extracting chlorogenic acid from Eucommia ulmoides leaves according to claim 6, characterized in that: The bottom end of the electric push rod (206) is fixedly connected to a pressing plate (207), and the vertical center line of the pressing plate (207) coincides with the vertical center line of the fixing ring (203).

8. The preparation equipment for extracting chlorogenic acid from Eucommia ulmoides leaves according to claim 4, characterized in that: The outer wall of the fixing ring (203) is provided with an additional filter plate assembly (3), and the additional filter plate assembly (3) comprises a mounting plate (301). The outer wall of the fixing ring (203) is fixedly connected with the mounting plate (301), and the number of the mounting plates (301) is two, and the two mounting plates (301) are symmetrically arranged with the vertical center line of the fixing ring (203) as a symmetry axis.

9. The preparation equipment for extracting chlorogenic acid from Eucommia ulmoides leaves according to claim 8, characterized in that: A through hole (302) is provided on the top of the mounting plate (301) and the top of the filter plate (202), and a bolt (303) is movably connected to the inner wall of the through hole (302); The shape and size of the bolt (303) match those of the through hole (302), and a nut (304) is threadedly connected to the outer wall of the bolt (303).

10. The method for preparing the equipment for extracting chlorogenic acid from Eucommia ulmoides leaves according to claims 1-9, characterized in that: The following steps are involved: Step S1: Open the cover plate (4) by means of the handle (5), and then pull the pull rod (204), so that the pull rod (204) drives the remaining components of the extraction and filtration mechanism (2) and the additional filter plate assembly (3) to rise synchronously, thereby pulling up the filter plate (202); Step S2: placing the crushed Eucommia leaf particles into the fixing ring (203), and then starting the electric push rod (206), so that the electric push rod (206) begins to extend, and the electric push rod (206) drives the pressing plate (207) to begin to descend, so that the pressing plate (207) fixes the Eucommia leaf particles, and the Eucommia leaf is squeezed by the pressing plate (207); Step S3: placing the filter plate (202) on the clamping ring (201) and fixing it by using the pull rod (204); Step S4: pour the prepared 70% ethanol into the preparation cylinder (1), and then start the heating element (8). At this time, start the electric push rod (206) in reverse, so that the pressing plate (207) is released from the control of the Eucommia leaf particles, so that the chlorogenic acid in the Eucommia leaf is dissolved in the 70% ethanol through immersion in 70% ethanol, thereby completing the extraction work; Step S5: Open the cover plate (4) by means of the handle (5), pull the pull rod (204), and pull the filter plate out of the preparation cylinder (1). When the filter plate (202) is pulled out upward, impurities in the water and the residue of the Eucommia leaf particles can be filtered onto the filter plate (202) and pulled out together with the filter plate (202); Step S6: the water pump (7) discharges the extract in the preparation tube (1) out of the preparation tube (1) through the pipeline (6), and the extract is collected in a container for later use; Step S7: recovering ethanol from the extract at 50-60° C. under reduced pressure until there is no alcohol taste, and extracting again to obtain an extract; Step S8: After adding activated carbon to the extract, boiling and filtering to obtain a filtrate, the filtrate is spray-dried and cyclone-dried to obtain chlorogenic acid powder.

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