A method for refining fermented organic acid

Abstract

The invention relates to the technical field of refining methods, and specifically discloses a method for refining fermented organic acids, comprising the following steps: heating inactivation, acidification, separation of an organic phase and an aqueous phase, filtering to remove solids, cooling, filtering, and drying; and in the process of filtering to remove solids, detecting the amount of solid residues in the organic phase after filtration to evaluate the solid removal effect of the adsorbent; and also comprising: in the process of filtering to remove solids, optimizing the selection process of the adsorbent; the invention can quickly identify the adsorbent with the best solid removal effect and the highest stability, and through a scientific and rigorous experimental design and evaluation system, provides strong support for the selection of adsorbents in the refining process of fermented organic acids, which not only improves the refining efficiency but also ensures the product quality.

Description

Technical Field

[0001] The invention relates to the technical field of refining methods, and in particular to a method for refining fermented organic acids. Background Art

[0002] Organic acids refer to some organic compounds with acidity. The most common organic acid is carboxylic acid (R-COOH), whose acidity comes from the carboxyl group (-COOH). Sulfonic acid (R-SO3H), sulfinic acid (R-SOOH), thiocarboxylic acid (R-SH) and others are also organic acids.

[0003] The Chinese invention patent with the announcement number CN103772186B discloses a method for refining fermented organic acids. The method comprises: I, heating and inactivating the terminated fermentation liquid; II, acidifying to crystallize the organic acid and obtain an organic acid crystallization aqueous solution; III, directly mixing the organic acid crystallization aqueous solution with an ether solvent to dissolve the organic acid, and separating the organic phase and the aqueous phase; IV, adding an adsorbent to the organic phase obtained in step III, filtering and removing solids; V, cooling the organic phase obtained in step IV until the organic acid crystallizes, filtering to obtain an organic acid crystallization filter cake, and drying the filter cake to obtain a refined organic acid product. The method of the present invention uses an ether solvent to refine organic acids, shortens the process flow, saves equipment, time and energy consumption, and can obtain organic acids with a purity greater than 99.5wt%, which is more suitable for industrial production.

[0004] In the production and refining process of organic acids, although the existing technology can meet the production needs to a certain extent, it still faces key problems such as poor adsorption effect and improper adsorbent selection. Specifically, many traditional refining methods use adsorption steps to remove impurities, but the adsorption effect is often unsatisfactory, resulting in the final product purity being difficult to meet the expected standards. This not only affects the application performance of organic acids, but also increases the difficulty and cost of subsequent processing.

[0005] In addition, the choice of adsorbent is also one of the key factors affecting the refining effect. There are many types of adsorbents available, but not all of them are suitable for the refining of organic acids. Improperly selected adsorbents may lead to low adsorption efficiency and even introduce new impurities, further affecting the quality and safety of the product. Summary of the invention

[0006] The object of the present invention is to provide a method for purifying fermented organic acids to solve at least one of the above-mentioned problems of the prior art.

[0007] The present invention provides a method for refining fermented organic acid, comprising the following steps: heating inactivation, acidification, separation of organic phase and aqueous phase, filtering to remove solids, cooling, filtering, and drying;

[0008] In the process of filtering and removing solids, the amount of solid residue in the organic phase after filtration is tested to evaluate the effect of the adsorbent in removing solids;

[0009] It also includes: optimizing the selection process of the adsorbent during the filtration and solid removal process, the specific process is:

[0010] B1: Use different adsorbents to perform filtration and removal experiments on solids in the organic phase to obtain the removal capacity coefficients of different adsorbents;

[0011] B2: Sort different adsorbents in descending order of their removal capacity coefficients, and give priority to the adsorbents with the highest ranking.

[0012] As a further solution of the present invention: the process of filtering and removing solids is:

[0013] Add adsorbent to the organic phase and filter to remove solids.

[0014] As a further solution of the present invention: the specific process of evaluating the effect of the adsorbent on removing solids is as follows:

[0015] A1: During the filtration process, the amount of solid residue in the organic phase is periodically tested to obtain the mass fraction of solids in the organic phase in each test period;

[0016] A2: Based on the quality scores of all sample detection points in each detection cycle, the discrete value and offset value of each detection cycle are obtained respectively, and then the discrete value and the offset value are summed up to obtain the filtering effect characterization value;

[0017] A3: Evaluate the solid removal effect of the adsorbent based on the filtration effect characterization value.

[0018] As a further solution of the present invention: the process of obtaining the mass fraction is:

[0019] Extracting a sample from the sampling area and obtaining a sampling volume of the sample;

[0020] The sample is placed on a heating device to evaporate the ether solvent until the sample is completely dry to obtain the remaining solids, and the mass of the remaining solids is weighed by a precision balance to obtain the mass of the remaining solids;

[0021] Calculate the ratio of the remaining solid mass to the sample volume, and then multiply by 100% to obtain the mass fraction.

[0022] As a further solution of the present invention: the process of obtaining discrete values ​​is:

[0023] By formula: , calculate and obtain the discrete representation value of the i-th detection cycle , where n is the number of sample detection points, represents the quality score of the kth sample detection point in the i-th detection cycle, represents the average quality score of all adjacent sample detection points of the kth sample detection point in the i-th detection cycle, It represents the range of quality scores of all sample detection points in the i-th detection cycle, It represents the average quality score of all sample detection points in the i-th detection cycle;

[0024] By formula: , calculate and obtain the change representation value of the i-th detection cycle;

[0025] By formula: , calculate the discrete value of the i-th detection cycle , where T represents the preset change characterization threshold.

[0026] As a further solution of the present invention: the process of obtaining the offset value is:

[0027] Extract the quality score of each sample detection point, and perform difference calculation with the quality score cycle threshold to obtain the detection point cycle effect value;

[0028] If the periodic effect value of the test point is less than or equal to 0, the quality score of the sample test point is marked as the qualified quality score;

[0029] If the periodic effect value of the test point is greater than 0, the quality score of the sample test point is marked as a substandard quality score;

[0030] All substandard quality scores are summed up to obtain the offset value.

[0031] As a further solution of the present invention: Based on the filtration effect characterization value, the process of evaluating the solid removal effect of the adsorbent is as follows:

[0032] Preset a filtering effect characterization threshold, and compare and analyze the filtering effect characterization value of each detection cycle with the filtering effect characterization threshold;

[0033] If the filtration effect characterization value is less than or equal to the filtration effect characterization threshold, it is determined that the solid removal effect of the adsorbent in the corresponding detection period is excellent, and a period removal standard-reaching signal is generated;

[0034] If the filtration effect characterization value is greater than the filtration effect characterization threshold, it is determined that the adsorbent's solid removal effect in the corresponding detection period is poor, and a period removal failure signal is generated.

[0035] As a further solution of the present invention: the process of obtaining the removal capacity coefficients of different adsorbents is:

[0036] The periodic standard-reaching characterization values ​​and the removal stability characterization values ​​corresponding to different adsorbents are obtained respectively, and the periodic standard-reaching characterization values ​​and the removal stability characterization values ​​are summed up and calculated to obtain the removal capacity coefficient.

[0037] As a further solution of the present invention: the process of obtaining the periodic standard characterization value is as follows:

[0038] Based on the filtration removal experiment of any adsorbent, the number of times the periodic removal standard-reaching signal is generated is extracted to obtain the periodic standard-reaching number;

[0039] Then, the ratio of the number of cycles that meet the standard to the total number of detection cycles is calculated to obtain the cycle standard characterization value.

[0040] As a further solution of the present invention: the process of obtaining the stable characterization value is as follows:

[0041] Based on all the periodic removal failure signals in any adsorbent filtration removal experiment, the periodic removal failure signals are marked as the removal failure period;

[0042] By formula: , calculate and obtain the removal stability characterization value Q, where m represents the total number of removal cycles that do not meet the standard, represents the sampling time of the rth non-standard removal cycle, represents the sampling time of the r-1th non-standard removal cycle, Represented as the preset first hyperparameter, represents the discrete value of the rth unqualified cycle, It represents the average value of all discrete values ​​excluding the periods that do not meet the standard. exp() is an exponential function with a natural constant as the base, and e is a natural constant.

[0043] Beneficial effects of the present invention:

[0044] 1. The present invention uses discrete values ​​and offset values ​​to conduct a comprehensive and in-depth evaluation of the removal effect of the adsorbent. The discrete value reveals the uniformity of solid distribution in the organic phase and the difference in the effect of the adsorbent in the removal process by comprehensively considering multiple dimensions such as the extreme difference, the average value, and the difference between adjacent points. The offset value intuitively demonstrates the overall performance of the adsorbent in removing solids by comparing the actual mass fraction with the preset mass fraction threshold, thereby achieving effective monitoring of the residual solid content in the organic phase during the filtration process and accurately evaluating the removal effect of the adsorbent, thereby ensuring that the organic acid product finally obtained has a high purity;

[0045] 2. The present invention quantitatively evaluates the performance of each adsorbent through the periodic standard characterization value and the removal stability characterization value. The periodic standard characterization value reflects the frequency of the adsorbent reaching the preset removal standard within the continuous filtration cycle, while the removal stability characterization value measures the stability of the adsorbent during use by calculating the discrete degree of the removal non-standard signal and combining the time weight, and then calculates the removal capacity coefficient as the evaluation standard of the comprehensive performance of the adsorbent. By comparing the removal capacity coefficients of different adsorbents, the adsorbents are ranked, so that the adsorbent with the best solid removal effect and the highest stability can be quickly identified. Through scientific and rigorous experimental design and evaluation system, it provides strong support for the selection of adsorbents in the refining process of fermented organic acids, which not only improves the refining efficiency but also ensures product quality. BRIEF DESCRIPTION OF THE DRAWINGS

[0046] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0047] Figure 1 This is a flow chart of a method for purifying a fermented organic acid provided in Example 1 of the present invention;

[0048] Figure 2 This is a flow chart of a method for purifying a fermented organic acid provided in Example 2 of the present invention;

[0049] Figure 3 This is a flow chart of a method for purifying a fermented organic acid provided in Example 3 of the present invention;

[0050] Figure 4 It is a structural schematic diagram of a fermentation organic acid refining device provided in Example 5 of the present invention.

[0051] In the figure: 3, computer device; 301, processor; 302, memory; 303, computer program. DETAILED DESCRIPTION

[0052] In order to enable those skilled in the art to better understand the scheme of the present invention, the technical scheme in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work should fall within the scope of protection of the present invention.

[0053] Embodiment 1

[0054] Figure 1 A flowchart of a fermentation organic acid refining method provided in Example 1 of the present invention, the embodiment of the present invention can be applied to the case of a fermentation organic acid refining method, the fermentation organic acid refining method can be performed by a fermentation organic acid refining system, the fermentation organic acid refining system can be implemented by software and / or hardware, and the fermentation organic acid refining system can be configured in a fermentation organic acid refining device. Optionally, a fermentation organic acid refining device can be an electronic device, which can be a notebook, a desktop computer, a smart tablet, etc., and the embodiment of the present invention does not limit this.

[0055] like Figure 1 As shown, a method for refining a fermented organic acid provided by an embodiment of the present invention specifically comprises the following steps:

[0056] S1: heating and inactivating the terminated fermentation liquid;

[0057] The terminated fermentation broth is a metabolite obtained by fermenting liquid wax by microorganisms. The fermentation broth is a complex multiphase system, which contains unreacted liquid wax, microbial cells and fragments, unused culture medium, metabolites, microbial secretions, proteins and pigments.

[0058] S2: Acidification to cause the organic acid to crystallize and obtain an organic acid crystal aqueous solution;

[0059] S3: directly mixing the organic acid crystal aqueous solution with an ether solvent to dissolve the organic acid, and separating the organic phase and the aqueous phase;

[0060] Wherein, the ether solvent is one or more of n-propyl ether, isopropyl ether, n-butyl ether, isobutyl ether, and isoamyl ether; the organic acid crystalline aqueous solution and the ether solvent are dissolved under heating conditions, and the heating temperature is 50 to 140° C.;

[0061] S4: adding an adsorbent to the organic phase obtained in S3, and filtering to remove solids;

[0062] S5: The organic phase obtained in S4 is cooled until the organic acid crystals are precipitated, and the organic acid crystal filter cake is obtained by filtering. The filter cake is dried to obtain a refined organic acid product, and the purity of the organic acid product is above 99.5wt%.

[0063] Embodiment 2

[0064] Based on Example 1, during the addition and filtration of the adsorbent, solids must be effectively removed to avoid contamination of the organic acid product. Figure 2As shown, a method for purifying a fermented organic acid according to an embodiment of the present invention further comprises: detecting the amount of solid residues in the organic phase after filtration to evaluate the effect of the adsorbent in removing solids, and the specific method comprises the following steps:

[0065] Based on Example 1, during the addition and filtration of the adsorbent, solids must be effectively removed to avoid contamination of the organic acid product. Figure 2 As shown, a method for purifying a fermented organic acid according to an embodiment of the present invention further includes: detecting the amount of solid residues in the organic phase during the filtration process to evaluate the effect of the adsorbent in removing solids, and the specific method is the following steps:

[0066] A1: During the filtration process, the amount of solid residue in the organic phase is periodically tested to obtain the mass fraction of solids in the organic phase in each test period;

[0067] In some embodiments, a plurality of sample detection points are preset in the organic phase, and at the end time point of the detection cycle, a sample is weighed from each sample detection point to obtain the sample amount;

[0068] Glossary: ​​Sampling volume refers to the mass of the organic phase sample taken;

[0069] The sample is placed on a heating device to evaporate the ether solvent until the sample is completely dry to obtain the remaining solids, and the mass of the remaining solids is weighed by a precision balance to obtain the mass of the remaining solids;

[0070] The heating device includes but is not limited to: electric heating plate, vacuum drying oven;

[0071] Calculate the ratio of the remaining solid mass to the sampling volume, then multiply by 100% to obtain the mass fraction of each sample test point;

[0072] A2: Based on the quality scores of all sample detection points in each detection cycle, the discrete value and offset value of each detection cycle are obtained respectively, and then the discrete value and the offset value are summed up to obtain the filtering effect characterization value;

[0073] Specifically, the process of obtaining discrete values ​​is:

[0074] By formula: , calculate and obtain the discrete representation value of the i-th detection cycle , where n is the number of sample detection points, represents the quality score of the kth sample detection point in the i-th detection cycle, represents the average quality score of all adjacent sample detection points of the kth sample detection point in the i-th detection cycle, It represents the range of quality scores of all sample detection points in the i-th detection cycle, It represents the average quality score of all sample detection points in the i-th detection cycle;

[0075] By formula: , calculate and obtain the change representation value of the i-th detection cycle;

[0076] By formula: , calculate the discrete value of the i-th detection cycle , where T represents the preset change characterization threshold;

[0077] The process of obtaining the offset value is:

[0078] Extract the quality score of each sample detection point, and perform difference calculation with the quality score cycle threshold to obtain the detection point cycle effect value;

[0079] It should be explained that the mass score cycle threshold represents the preset mass score of each sample detection point in the corresponding detection cycle, and this value is an empirical value;

[0080] If the detection point period effect value is less than or equal to 0, it means that the removal effect of the sample detection point corresponding to the detection point period effect value in the detection period reaches the preset effect, and the quality score of the sample detection point is marked as the qualified quality score;

[0081] If the detection point period effect value is greater than 0, it means that the removal effect of the sample detection point corresponding to the detection point period effect value in the detection period does not reach the preset effect, and the quality score of the sample detection point is marked as a substandard quality score;

[0082] All substandard quality scores are summed up to obtain an offset value;

[0083] Preset a filtering effect characterization threshold, and compare and analyze the filtering effect characterization value of each detection cycle with the filtering effect characterization threshold;

[0084] If the filtration effect characterization value is less than or equal to the filtration effect characterization threshold, it means that the difference between the residual solid amount in the organic phase and the set amount in the detection period corresponding to the filtration effect characterization value is small, and the uniformity of the adsorption effect is good, that is, it is determined that the adsorbent has an excellent solid removal effect in the corresponding detection period, and a period removal standard-reaching signal is generated;

[0085] If the filtration effect characterization value is greater than the filtration effect characterization threshold, it means that the residual solid amount in the organic phase in the detection period corresponding to the filtration effect characterization value is greatly different from the set amount, and the uniformity of the adsorption effect is poor, that is, it is determined that the adsorbent has a poor solid removal effect in the corresponding detection period, and a period removal failure signal is generated;

[0086] The technical solution of the embodiment of the present invention is mainly as follows: a comprehensive and in-depth evaluation of the removal effect of the adsorbent is performed through discrete values ​​and offset values. The discrete value reveals the uniformity of the distribution of solids in the organic phase and the difference in the effect of the adsorbent in the removal process by comprehensively considering multiple dimensions such as the extreme difference, the average value, and the difference in adjacent point differences. The offset value intuitively demonstrates the overall effectiveness of the adsorbent in removing solids by comparing the actual mass fraction with the preset mass fraction threshold, thereby achieving effective monitoring of the residual solids in the organic phase during the filtration process and accurately evaluating the removal effect of the adsorbent, thereby ensuring that the final organic acid product has a high purity.

[0087] Embodiment 3

[0088] Based on Example 1 and Example 2, during the process of adding the adsorbent and filtering, the selection of the adsorbent can help remove the solids more effectively and quickly. Please refer to Figure 3 As shown, a method for refining a fermented organic acid according to an embodiment of the present invention further includes: in the process of adding and filtering the adsorbent, optimizing the selection process of the adsorbent to ensure that the solids are removed more effectively and quickly, and the specific method is the following steps:

[0089] B1: Filter and remove solids from the organic phase using different adsorbents;

[0090] It should be explained that in the experiment of filtering and removing solids from the organic phase using different adsorbents, the type of adsorbent is the only variable in each experiment, and other experimental conditions need to be the same in each experiment, such as: filtration time, organic phase properties (temperature, viscosity, HP value), solid concentration, and filtration equipment;

[0091] The periodic standard characterization values ​​and the removal stability characterization values ​​corresponding to different adsorbents are respectively obtained, and the periodic standard characterization values ​​and the removal stability characterization values ​​are summed and calculated to obtain the removal capacity coefficient;

[0092] Specifically, the process of obtaining the periodic target characterization value is as follows:

[0093] Based on the filtration removal experiment of any adsorbent, the number of times the periodic removal standard-reaching signal is generated is extracted to obtain the periodic standard-reaching number;

[0094] Then, the ratio of the number of cycles that meet the standard to the total number of detection cycles is calculated to obtain the cycle standard characterization value;

[0095] The process of obtaining the destabilization characterization value is as follows:

[0096] Based on all the periodic removal failure signals in any adsorbent filtration removal experiment, the periodic removal failure signals are marked as the removal failure period;

[0097] By formula: , calculate and obtain the removal stability characterization value Q, where m represents the total number of removal cycles that do not meet the standard, represents the sampling time of the rth non-standard removal cycle, represents the sampling time of the r-1th non-standard removal cycle, Represented as the preset first hyperparameter, represents the discrete value of the rth unqualified cycle, It represents the average value of all discrete values ​​excluding the periods that do not meet the standard, exp() is an exponential function with a natural constant as the base, and e is a natural constant;

[0098] The exemplary preset first hyperparameter is 0.01. In specific applications, the implementer can set it according to the specific situation, but it is necessary to ensure that the preset first hyperparameter is greater than 0;

[0099] It needs to be explained that represents the first product corresponding to the sampling time of the rth period of removing non-standard items, Indicates the first eigenvalue of the rth non-standard removal period sampling time in the current time period. The first eigenvalue is used as the weight value. The larger the time interval between the rth non-standard removal period sampling time and the r-1th non-standard removal period sampling time, the smaller the corresponding weight value, and the smaller the impact on the overall fluctuation of all discrete values ​​in the filtering process;

[0100] It should be further explained that the larger the value of the removal stability characterization value, the higher the stability of the corresponding adsorbent in the filtration removal experiment;

[0101] B2: Sort different adsorbents in descending order of their removal capacity coefficient values. The higher the ranking of the adsorbent, the smaller the value of its adsorbent removal capacity coefficient, that is, when the filtration time is fixed, the better the solid removal effect of the adsorbent, so in the process of selecting different adsorbents, the higher the ranking of the adsorbent, the better the solid removal effect of the adsorbent;

[0102] The technical solution of the embodiment of the present invention is mainly as follows: the performance of each adsorbent is quantitatively evaluated through the periodic standard characterization value and the removal stability characterization value. The periodic standard characterization value reflects the frequency of the adsorbent reaching the preset removal standard within the continuous filtration cycle, while the removal stability characterization value measures the stability of the adsorbent during use by calculating the discrete degree of the removal non-standard signal and combining the time weight, and then calculates the removal capacity coefficient as the evaluation standard of the comprehensive performance of the adsorbent. By comparing the removal capacity coefficients of different adsorbents, the adsorbents are ranked, so that the adsorbent with the best solids removal effect and the highest stability can be quickly identified. Through scientific and rigorous experimental design and evaluation system, it provides strong support for the selection of adsorbents in the fermentation organic acid refining process, which not only improves the refining efficiency but also ensures product quality.

[0103] Embodiment 4

[0104] On the basis of Example 1, Example 2 and Example 3, a fermentation organic acid purification system according to an embodiment of the present invention comprises:

[0105] Removal evaluation module: During the solid removal process, the residual solids in the organic phase after filtration are tested to evaluate the solid removal effect of the adsorbent;

[0106] It also includes: optimizing the selection process of the adsorbent during the filtration and solid removal process, specifically:

[0107] Removal capacity acquisition module: Use different adsorbents to perform filtration and removal experiments on solids in the organic phase to obtain the removal capacity coefficients of different adsorbents;

[0108] Removal capacity ranking module: sort different adsorbents according to the descending order of the removal capacity coefficient values ​​of different adsorbents.

[0109] Embodiment 5

[0110] Reference Figure 4 The embodiment of the present invention further provides a computer device 3, comprising: a memory 302 and a processor 301 and a computer program 303 stored in the memory 302. When the computer program 303 is executed on the processor 301, a method for refining a fermented organic acid as described in any one of the above methods is implemented.

[0111] The computer device 3 may be a computing device such as a desktop computer, a notebook, a PDA, or a cloud server. The computer device 3 may include, but is not limited to, a processor 301 and a memory 302. Those skilled in the art will appreciate that

[0112] Figure 4It is only an example of computer device 3 and does not constitute a limitation on computer device 3. It may include more or fewer components than shown in the figure, or a combination of certain components, or different components, for example, it may also include input and output devices, network access devices, etc.

[0113] The processor 301 may be a central processing unit (CPU), or other general-purpose processors, digital signal processors (DSP), application-specific integrated circuits (ASIC), field-programmable gate arrays (FPGA) or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, etc. A general-purpose processor may be a microprocessor or any conventional processor, etc.

[0114] In some embodiments, the memory 302 may be an internal storage unit of the computer device 3, such as a hard disk or memory of the computer device 3. In other embodiments, the memory 302 may also be an external storage device of the computer device 3, such as a plug-in hard disk, a smart memory card (Smart Media Card, SMC), a secure digital (Secure Digital, SD) card, a flash card (Flash Card), etc. equipped on the computer device 3. Further, the memory 302 may also include both an internal storage unit of the computer device 3 and an external storage device. The memory 302 is used to store an operating system, an application program, a boot loader (BootLoader), data, and other programs, such as the program code of the computer program, etc. The memory 302 may also be used to temporarily store data that has been output or is to be output.

[0115] Embodiment 6

[0116] An embodiment of the present invention further provides a computer-readable storage medium having a computer program stored thereon. When the computer program is executed by a processor, a method for purifying a fermented organic acid as described in any one of the above methods is implemented.

[0117] In this embodiment, if the integrated unit is implemented in the form of a software functional unit and sold or used as an independent product, it can be stored in a computer-readable storage medium. Based on this understanding, the present application implements all or part of the processes in the above-mentioned embodiment method, which can be completed by instructing the relevant hardware through a computer program. The computer program can be stored in a computer-readable storage medium. When the computer program is executed by the processor, the steps of the above-mentioned various method embodiments can be implemented. Among them, the computer program includes computer program code, and the computer program code can be in source code form, object code form, executable file or some intermediate form. The computer-readable medium can at least include: any entity or device that can carry the computer program code to the camera / terminal device, recording medium, computer memory, read-only memory (ROM, Read-Only Memory), random access memory (RAM, Random Access Memory), electric carrier signal, telecommunication signal and software distribution medium. For example, USB flash drive, mobile hard disk, disk or optical disk. In some jurisdictions, according to legislation and patent practice, computer-readable media cannot be electric carrier signals and telecommunication signals.

[0118] In the above embodiments, the description of each embodiment has its own emphasis. For parts that are not described or recorded in detail in a certain embodiment, reference can be made to the relevant descriptions of other embodiments.

[0119] Those of ordinary skill in the art will appreciate that the units and algorithm steps of each example described in conjunction with the embodiments disclosed herein can be implemented in electronic hardware, or a combination of computer software and electronic hardware. Whether these functions are performed in hardware or software depends on the specific application and design constraints of the technical solution. Professional and technical personnel can use different methods to implement the described functions for each specific application, but such implementation should not be considered to be beyond the scope of this application.

[0120] In the embodiments disclosed in the present application, it should be understood that the disclosed apparatus / terminal equipment and method can be implemented in other ways. For example, the apparatus / terminal equipment embodiments described above are merely illustrative. For example, the division of the modules or units is only a logical function division. There may be other division methods in actual implementation. For example, multiple units or components can be combined or integrated into another system, or some features can be ignored or not executed.

[0121] One point, the mutual coupling or direct coupling or communication connection shown or discussed may be an indirect coupling or communication connection through some interface, device or unit, which may be electrical, mechanical or other forms.

[0122] The units described as separate components may or may not be physically separated, and the components shown as units may or may not be physical units, that is, they may be located in one place or distributed on multiple network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.

[0123] The above formulas are all dimensionless and numerical calculations. The formula is a formula for the most recent real situation obtained by collecting a large amount of data and performing software simulation. The preset parameters in the formula are set by technicians in this field according to actual conditions.

[0124] The above is a detailed description of an embodiment of the present invention, but the content is only a preferred embodiment of the present invention and cannot be considered to limit the scope of implementation of the present invention. All equivalent changes and improvements made within the scope of the present invention should still fall within the scope of the patent coverage of the present invention.

Claims

1. A method for purifying a fermented organic acid, characterized in that: The following steps are involved: Heat inactivation, acidification, separation of organic phase and aqueous phase, filtration to remove solids, cooling, filtration, and drying; In the process of filtering and removing solids, the amount of solid residue in the organic phase after filtration is tested to evaluate the effect of the adsorbent in removing solids; It also includes: optimizing the selection process of the adsorbent during the filtration and solid removal process, the specific process is: B1: Use different adsorbents to perform filtration and removal experiments on solids in the organic phase to obtain the removal capacity coefficients of different adsorbents; the process of obtaining the removal capacity coefficients of different adsorbents is as follows: The periodic standard characterization values ​​and the removal stability characterization values ​​corresponding to different adsorbents are respectively obtained, and the periodic standard characterization values ​​and the removal stability characterization values ​​are summed and calculated to obtain the removal capacity coefficient; The process of obtaining the destabilization characterization value is as follows: Based on all the periodic removal failure signals in any adsorbent filtration removal experiment, the periodic removal failure signals are marked as the removal failure period; By formula: , calculate and obtain the removal stability characterization value Q, where m represents the total number of removal cycles that do not meet the standard, represents the sampling time of the rth non-standard removal cycle, represents the sampling time of the r-1th non-standard removal cycle, Represented as the preset first hyperparameter, represents the discrete value of the rth unqualified cycle, It represents the average value of all discrete values ​​excluding the periods that do not meet the standard, exp() is an exponential function with a natural constant as the base, and e is a natural constant; B2: Sort different adsorbents in descending order of their removal capacity coefficients, and give priority to the adsorbents with the highest ranking.

2. The method for refining a fermented organic acid according to claim 1, characterized in that: The process of filtering and removing solids is: Add adsorbent to the organic phase and filter to remove solids.

3. The method for refining a fermented organic acid according to claim 1, characterized in that: The specific process of evaluating the effect of adsorbent in removing solids is as follows: A1: During the filtration process, the amount of solid residue in the organic phase is periodically tested to obtain the mass fraction of solids in the organic phase in each test period; A2: Based on the quality scores of all sample detection points in each detection cycle, the discrete value and offset value of each detection cycle are obtained respectively, and then the discrete value and the offset value are summed up to obtain the filtering effect characterization value; A3: Evaluate the solid removal effect of the adsorbent based on the filtration effect characterization value.

4. The method for purifying a fermented organic acid according to claim 3, characterized in that: The process of obtaining the quality score is as follows: Extracting a sample from the sampling area and obtaining a sampling volume of the sample; The sample is placed on a heating device to evaporate the ether solvent until the sample is completely dry to obtain the remaining solids, and the mass of the remaining solids is weighed by a precision balance to obtain the mass of the remaining solids; Calculate the ratio of the remaining solid mass to the sample volume, and then multiply by 100% to obtain the mass fraction.

5. The method for purifying a fermented organic acid according to claim 3, characterized in that: The process of obtaining discrete values ​​is: By formula: , calculate and obtain the discrete representation value of the i-th detection cycle , where n is the number of sample detection points, represents the quality score of the kth sample detection point in the i-th detection cycle, represents the average quality score of all adjacent sample detection points of the kth sample detection point in the i-th detection cycle, It represents the range of quality scores of all sample detection points in the i-th detection cycle, It represents the average quality score of all sample detection points in the i-th detection cycle; By formula: , calculate and obtain the change representation value of the i-th detection cycle; By formula: , calculate the discrete value of the i-th detection cycle , where T represents the preset change characterization threshold.

6. The method for purifying a fermented organic acid according to claim 3, characterized in that: The process of obtaining the offset value is: Extract the quality score of each sample detection point, and perform difference calculation with the quality score cycle threshold to obtain the detection point cycle effect value; If the periodic effect value of the test point is less than or equal to 0, the quality score of the sample test point is marked as the qualified quality score; If the periodic effect value of the test point is greater than 0, the quality score of the sample test point is marked as a substandard quality score; All substandard quality scores are summed up to obtain the offset value.

7. The method for purifying a fermented organic acid according to claim 3, characterized in that: Based on the filtration effect characterization value, the process of evaluating the adsorbent's solid removal effect is as follows: Preset a filtering effect characterization threshold, and compare and analyze the filtering effect characterization value of each detection cycle with the filtering effect characterization threshold; If the filtration effect characterization value is less than or equal to the filtration effect characterization threshold, it is determined that the solid removal effect of the adsorbent in the corresponding detection period is excellent, and a period removal standard-reaching signal is generated; If the filtration effect characterization value is greater than the filtration effect characterization threshold, it is determined that the adsorbent's solid removal effect in the corresponding detection period is poor, and a period removal failure signal is generated.

8. The method for purifying a fermented organic acid according to claim 1, characterized in that: The process of obtaining the periodic compliance characterization value is as follows: Based on the filtration removal experiment of any adsorbent, the number of times the periodic removal standard-reaching signal is generated is extracted to obtain the periodic standard-reaching number; Then, the ratio of the number of cycles that meet the standard to the total number of detection cycles is calculated to obtain the cycle standard characterization value.

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