Rapid crystallization device for clindamycin phosphate

Abstract

The present invention discloses a clindamycin phosphate rapid crystallization apparatus, and particularly relates to the technical field of crystallization apparatuses, the clindamycin phosphate rapid crystallization apparatus comprises a base, the base is provided with a separation crystallization assembly, the separation crystallization assembly comprises a crystallization cylinder arranged on the top of the base, and the top of the crystallization cylinder is sleeved with a heating cylinder. Raw materials between the lining filter cylinder and the locking block can be separated through the lining filter cylinder, impurities can be reserved in the lining filter cylinder, the raw materials can be easily separated and filtered, the follow-up crystallization efficiency and effect of the raw materials are ensured, heat conduction heating is conducted through the second flow dividing cone block, and the crystallization efficiency of the raw materials is improved. The separated raw materials are crystallized in the crystallization cylinder and are gathered together through the filter element, so that the resistance between the raw materials and the extension rod and the filter element during rotation is increased, the stirring efficiency and effect of the raw materials during separation are improved, impurities are easily separated into the lining filter cylinder, and the crystallization effect of the separated raw materials is ensured.

Description

Technical Field

[0001] The present invention relates to the technical field of crystallization devices, and more particularly to a rapid crystallization device for clindamycin phosphate. Background Art

[0002] Clindamycin phosphate is an organic compound and also an antibiotic drug. Crystallization is a common method for separating and purifying solid substances. By controlling crystallization conditions, such as temperature, solvent, pH value, etc., a high-purity clindamycin phosphate crystalline product can be obtained. This high-purity product has better stability and efficacy and meets the requirements of pharmaceutical production. The crystallization process can change the physical properties of the drug, such as crystal form, particle size, solubility, etc. These changes in properties may help improve the solubility, bioavailability and stability of the drug. For example, certain crystal forms of clindamycin phosphate may be more soluble, thereby increasing the absorption rate and effect of the drug.

[0003] Among them, the patent with announcement number CN222218673U discloses a crystallization device, including a mother liquor tank, an oscillating temperature crystallization tube and a crystallization tank; the oscillating temperature crystallization tube includes a plurality of low-temperature crystallization tubes and a plurality of high-temperature dissolving crystal tubes, the plurality of low-temperature crystallization tubes are alternately connected with the plurality of high-temperature dissolving crystal tubes and the head and tail are both low-temperature crystallization tubes, wherein the mother liquor tank is connected to the first low-temperature crystallization tube in the oscillating temperature crystallization tube, and the crystallization tank is connected to the last low-temperature crystallization tube in the oscillating temperature crystallization tube; When the structure is in use, the mother liquor to be crystallized is finally collected in the crystallization tank from the mother liquor tank through the alternately arranged low-temperature crystallization tube and the oscillating temperature crystallization tube of the high-temperature crystal dissolving tube. The mother liquor to be crystallized can be cooled and heated in sequence uninterruptedly by the above device. The oscillating temperature crystallization can quickly obtain the crystallized material. However, the structure is not easy to filter out impurities when in use, resulting in the crystals containing impurities, resulting in lower molding quality. Summary of the invention

[0004] In order to overcome the above defects of the prior art, the present invention provides a rapid crystallization device for clindamycin phosphate, aiming to solve the problems raised in the above background technology.

[0005] The present invention provides the following technical solution: a rapid crystallization device for clindamycin phosphate, comprising a base, on which a separation crystallization component is arranged; The separation crystallization assembly comprises a crystallization cylinder arranged on the top of the base, a heating cylinder is sleeved on the top of the crystallization cylinder, a sealing ring is arranged between the crystallization cylinder and the heating cylinder, and a lining filter cylinder is arranged in the middle of the heating cylinder; A first diverter cone block is provided in the middle of the liner filter cartridge, a second diverter cone block is provided at the bottom of the first diverter cone block, the second diverter cone block is installed at the bottom of the inner cavity of the crystallization cylinder by bolts, and the first diverter cone block is rotatably connected to the second diverter cone block, and the vertical cross-section shape of the first diverter cone block and the second diverter cone block is set to be conical; A support plate is provided at the top of the inner cavity of the lining filter cartridge, a traction plate which can be adjusted up and down is provided at the bottom of the support plate, a plurality of extension rods with adjustable angles are distributed on the outside of the traction plate, and a filter element for filtering is provided at the bottom of each extension rod, a turntable is fixedly provided at the bottom of the first diversion cone block, a plurality of booster cross bars are distributed on the outside of the turntable, and the lining filter cartridge is installed on the turntable.

[0006] It can be seen that in the above technical solution, the raw materials are added into the crystallization cylinder and the heating cylinder, and then the connecting cover is buckled back, and the first diverter cone block is driven to rotate by the driving motor. When the first diverter cone block rotates, the locking block and the lining filter cylinder are driven to rotate, so that the raw materials between the lining filter cylinder and the locking block can be separated through the lining filter cylinder, while the impurities can be retained in the lining filter cylinder, and the separated raw materials can be stored at the bottom of the inner cavity of the crystallization cylinder, and at the same time, heat conduction heating is carried out through the second diverter cone block, so that the separated raw materials can be crystallized in the crystallization cylinder.

[0007] Optionally, in a possible embodiment, a limited seat is provided on the top of the support plate, and a rotating rod is rotatably connected to the middle part of the limited seat, and the rotating rod passes through the support plate and extends to the middle part of the traction plate, and the rotating rod is threadedly connected to the traction plate, and the top of the extension rod extends to the bottom of the support plate and is hinged to the support plate, and a plurality of axle pin seats are fixedly provided on the outer side of the traction plate, and each of the axle pin seats is hinged with an axle pin part, and a plurality of axle pin parts respectively extend to corresponding extension rods and are hinged with the extension rods, and a sealing cover is provided on the top of the crystallization cylinder, and an articulated frame is hinged on the sealing cover, and a connecting cover is fixedly provided on one end of the articulated frame, and a temperature sensor extending into the crystallization cylinder is provided on one side of the connecting cover, and the connecting cover is snap-connected with the sealing cover, and a handle is rotatably connected to the connecting cover, and the handle extends to the top of the rotating rod, and the limited seat and the support plate are both installed on the sealing cover; It can be seen that in the above technical scheme, by rotating the handle, the rotation of the handle drives the rotating rod to rotate, and the rotation of the rotating rod causes the traction plate to be displaced at the bottom of the support plate, and the displacement of the traction plate drives the axle pin to be displaced, so that the axle pin pulls the extension rod to rotate along the axis point of the connection between the extension rod and the support plate and the axle pin and the extension rod, thereby allowing each extension rod and the filter element to approach and gather together, so that when the raw materials are separated in the inner lining filter cartridge, each filter core can be inserted into the raw material, so that the raw material is obstructed during rotation, and the raw material is easy to stir during rotation. When the filter core extends into the raw material, impurities in the raw material can be filtered on the filter core, and by gathering the filter cores together, the resistance between the raw material and the extension rod and the filter core during rotation is increased, thereby improving the stirring efficiency and effect of the raw material during separation, and making it easy for impurities to be separated in the inner lining filter cartridge, thereby ensuring the crystallization effect of the raw material after separation.

[0008] Optionally, in a possible embodiment, a locking block is provided at the top of the first diverter cone block, and a driving motor is installed at the bottom of the crystallization cylinder by bolts, and the output end of the driving motor sequentially passes through the crystallization cylinder and the second diverter cone block and extends to the bottom end of the locking block, and the output end of the driving motor is rotatably connected to the crystallization cylinder and the second diverter cone block, and a plurality of supporting legs are distributed on the outside of the crystallization cylinder, and each of the supporting legs is installed on the outside of the lining filter cylinder by bolts, and a discharge pipe is provided at the bottom of the crystallization cylinder.

[0009] Technical effects and advantages of the present invention: 1. The present invention drives the first diverter cone block to rotate by a driving motor. When the first diverter cone block rotates, it drives the locking block and the inner liner filter cartridge to rotate, so that the raw materials between the inner liner filter cartridge and the locking block can be separated through the inner liner filter cartridge, while the impurities can be retained in the inner liner filter cartridge, which makes it easy to separate and filter the raw materials, thereby ensuring the subsequent raw material crystallization efficiency and effect; 2. The present invention allows the separated raw materials to be stored at the bottom of the inner cavity of the crystallization cylinder and to be heated by heat conduction through the second diverter cone block, so that the separated raw materials can be crystallized in the crystallization cylinder. At the same time, the raw materials pass through the conical sections of the first diverter cone block and the second diverter cone block, which facilitates the raw materials to diffuse to the outside of the first diverter cone block and the second diverter cone block during separation and subsequent crystallization, thereby avoiding the accumulation of raw materials; 3. The present invention drives the rotating rod to rotate by rotating the handle, and the rotating rod will cause the traction plate to be displaced at the bottom of the supporting plate when the traction plate is displaced, and the shaft pin will be displaced when the traction plate is displaced, so that the shaft pin pulls the extension rod to rotate along the axis point of the connection between the extension rod and the supporting plate and the shaft pin and the extension rod, and then each extension rod and the filter core can be close to and gathered together, which makes it easy for the raw materials to be separated in the liner filter cartridge, and each filter core can be inserted into the raw materials, so that the raw materials are blocked when rotating, and it is easy to stir the raw materials when rotating; 4. In the present invention, when the filter core is extended into the raw material, the impurities in the raw material can be filtered on the filter core, and the resistance between the raw material and the extension rod and the filter core is increased when the raw material rotates by gathering the filter core together, thereby improving the stirring efficiency and effect of the raw material during separation, making it easier for the impurities to be separated in the inner lining filter cartridge, and ensuring the crystallization effect of the raw material after separation; To sum up, the overall design is simple and the structure is reasonable. Through the corresponding coordination of various structures, the raw materials between the lining filter cartridge and the locking block can be separated through the lining filter cartridge, while impurities can remain in the lining filter cartridge, which is easy to separate and filter the raw materials, ensuring the subsequent raw material crystallization efficiency and effect. The separated raw materials can be stored at the bottom of the inner cavity of the crystallization cylinder, and at the same time, they are heated by heat conduction through the second diverter cone block, so that the separated raw materials can be crystallized in the crystallization cylinder, and at the same time, the conical cross-sections of the first diverter cone block and the second diverter cone block are convenient for the raw materials to diffuse to the outside of the first diverter cone block and the second diverter cone block during separation and subsequent crystallization, so as to avoid the accumulation of raw materials. When the filter element extends into the raw material, impurities in the raw material can be filtered on the filter element, and by gathering the filter elements together, it is achieved to increase the resistance between the raw material and the extension rod and the filter element during rotation, thereby improving the stirring efficiency and effect of the raw material during separation, and making it easy for impurities to be separated in the lining filter cartridge, ensuring the crystallization effect of the raw material after separation. BRIEF DESCRIPTION OF THE DRAWINGS

[0010] In order to more clearly illustrate the technical solutions in the present disclosure, the following briefly introduces the drawings required for use in some embodiments. Obviously, the drawings described below are only drawings of some embodiments of the present disclosure. For those of ordinary skill in the art, other drawings can also be obtained based on these drawings. In addition, the drawings described below can be regarded as schematic diagrams, and are not intended to limit the actual size of the product involved in the embodiments of the present disclosure, the actual process of the method, the actual timing of the signal, etc.

[0011] Figure 1 It is the front view of the overall structure of the present invention.

[0012] Figure 2 It is a cross-sectional view of the overall structure of the present invention.

[0013] Figure 3 It is a three-dimensional view of the sealing cover, hinged frame, connecting cover and handle of the present invention.

[0014] Figure 4 It is a stereoscopic diagram of the base, support legs, heating cylinder, lining filter cylinder and first diversion cone block of the present invention.

[0015] Figure 5 It is a schematic diagram of the first diverter cone block, the crystallization cylinder and the heating cylinder installed together in the present invention.

[0016] Figure 6 It is a stereoscopic diagram of the support plate, the limiting seat, the rotating rod, the pulling plate, the extension rod and the filter element of the present invention.

[0017] Figure 7 It is a three-dimensional diagram of the support plate, the limiting seat and the rotating rod of the present invention.

[0018] Figure 8 It is a stereoscopic diagram of the traction plate, the shaft pin, the extension rod and the filter element of the present invention.

[0019] Fig. 9 It is a stereoscopic diagram of the first diverter cone block, the locking block, the rotating disk and the booster cross bar of the present invention.

[0020] The accompanying drawings are marked as follows: 1. base; 2. crystallization cylinder; 3. heating cylinder; 4. inner lining filter cylinder; 5. first diverter cone block; 6. second diverter cone block; 7. limit seat; 8. support plate; 9. rotating rod; 10. traction plate; 11. axle pin; 12. extension rod; 13. filter element; 14. sealing cover; 15. hinged frame; 16. connecting cover; 17. handle; 18. axle pin seat; 19. turntable; 20. booster cross bar; 21. locking block; 22. support leg; 23. discharge pipe; 24. drive motor; 25. temperature sensor. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0022] As attached Figure 1 - Fig. 9The rapid crystallization device of clindamycin phosphate shown in the figure, through the separation crystallization assembly set on the base 1, through the corresponding cooperation of various structures, the raw materials between the lining filter cartridge 4 and the locking block 21 can be separated through the lining filter cartridge 4, and the impurities can be retained in the lining filter cartridge 4, which is easy to separate and filter the raw materials, ensuring the subsequent raw material crystallization efficiency and effect, the separated raw materials can be stored at the bottom of the inner cavity of the crystallization cylinder 2, and at the same time, the separated raw materials can be heated by heat conduction through the second diverter cone block 6, so that the separated raw materials can be crystallized in the crystallization cylinder 2, and at the same time, the first diverter cone block 5 and the second The conical cross section of the diverter cone block 6 facilitates the diffusion of the raw materials to the outside of the first diverter cone block 5 and the second diverter cone block 6 during separation and subsequent crystallization, thereby avoiding the accumulation of the raw materials. When the filter core 13 extends into the raw materials, the impurities in the raw materials can be filtered on the filter core 13. By gathering the filter core 13 together, the resistance between the raw materials and the extension rod 12 and the filter core 13 during rotation is increased, thereby improving the original stirring efficiency and effect during separation, making it easier for impurities to be separated in the inner liner filter cartridge 4, and ensuring the crystallization effect of the raw materials after separation. The specific structural arrangement of the components is as follows; The separation crystallization assembly comprises a crystallization cylinder 2 arranged on the top of the base 1, a heating cylinder 3 is sleeved on the top of the crystallization cylinder 2, a sealing ring is arranged between the crystallization cylinder 2 and the heating cylinder 3, and a lining filter cylinder 4 is arranged in the middle of the heating cylinder 3; A first diverter cone block 5 is provided in the middle of the liner filter cartridge 4, a second diverter cone block 6 is provided at the bottom of the first diverter cone block 5, the second diverter cone block 6 is installed at the bottom of the inner cavity of the crystallization cylinder 2 by bolts, and the first diverter cone block 5 is rotatably connected with the second diverter cone block 6, and the vertical cross-section shape of the first diverter cone block 5 and the second diverter cone block 6 is set to be conical; A support plate 8 is provided at the top of the inner cavity of the lining filter cartridge 4, and a traction plate 10 which can be adjusted up and down is provided at the bottom of the support plate 8. A plurality of angle-adjustable extension rods 12 are distributed on the outside of the traction plate 10, and a filter element 13 for filtering is provided at the bottom of each extension rod 12. A turntable 19 is fixedly provided at the bottom of the first diversion cone block 5, and a plurality of booster cross bars 20 are distributed on the outside of the turntable 19, and the lining filter cartridge 4 is installed on the turntable 19.

[0023] A limited seat 7 is provided at the top of the support plate 8, and a rotating rod 9 is rotatably connected to the middle of the limited seat 7. The rotating rod 9 passes through the support plate 8 and extends to the middle of the traction plate 10. The rotating rod 9 is threadedly connected to the traction plate 10. The top of the extension rod 12 extends to the bottom of the support plate 8 and is hinged to the support plate 8. A plurality of shaft pin seats 18 are fixedly provided on the outer side of the traction plate 10, and each shaft pin seat 18 is hinged with a shaft pin 11. The plurality of shaft pins 11 extend to the corresponding extension rods 12 and are respectively connected to the corresponding extension rods 12. The top of the crystallization cylinder 2 is hinged with the extension rod 12, and a sealing cover 14 is provided. A hinge frame 15 is hinged on the sealing cover 14, and a connecting cover 16 is fixedly provided at one end of the hinge frame 15. A temperature sensor 25 extending into the crystallization cylinder 2 is provided on one side of the connecting cover 16. The connecting cover 16 is snap-connected with the sealing cover 14, and a handle 17 is rotatably connected to the connecting cover 16, and the handle 17 extends to the top of the rotating rod 9, and the limiting seat 7 and the supporting plate 8 are both installed on the sealing cover 14; A locking block 21 is provided at the top of the first diverter cone block 5, and a driving motor 24 is installed at the bottom of the crystallization cylinder 2 by bolts. The output end of the driving motor 24 passes through the crystallization cylinder 2 and the second diverter cone block 6 in sequence and extends to the bottom end of the locking block 21. The output end of the driving motor 24 is rotatably connected to the crystallization cylinder 2 and the second diverter cone block 6. A plurality of supporting legs 22 are distributed on the outside of the crystallization cylinder 2, and each supporting leg 22 is installed on the outside of the lining filter cylinder 4 by bolts. A discharge pipe 23 is provided at the bottom of the crystallization cylinder 2.

[0024] According to the above structure, when in use, the staff installs the device at the designated position, opens the connection cover 16 through the hinge frame 15, adds the raw material into the crystallization cylinder 2 and the heating cylinder 3, then buckles the connection cover 16, and drives the first diverter cone block 5 to rotate through the driving motor 24. When the first diverter cone block 5 rotates, it drives the locking block 21 and the lining filter cartridge 4 to rotate, so that the raw material between the lining filter cartridge 4 and the locking block 21 can be separated through the lining filter cartridge 4, while the impurities can be retained in the lining filter cartridge 4. The separated raw material can be stored at the bottom of the inner cavity of the crystallization cylinder 2, and at the same time, it is heated by heat conduction through the second diverter cone block 6, so that the separated raw material can be crystallized in the crystallization cylinder 2; At the same time, when performing separation crystallization, by rotating the handle 17, the handle 17 rotates and drives the rotating rod 9 to rotate. When the rotating rod 9 rotates, the traction plate 10 will be displaced at the bottom of the supporting plate 8. When the traction plate 10 is displaced, the shaft pin 11 will be displaced, so that the shaft pin 11 pulls the extension rod 12 to rotate along the axis point where the extension rod 12 and the supporting plate 8 and the shaft pin 11 and the extension rod 12 are connected, and then each extension rod 12 and the filter core 13 are close to and gathered together, which makes it easy for the raw materials to be separated in the liner filter cartridge 4. Each filter core 13 can be inserted into the raw materials, so that the raw materials are blocked when rotating, and it is easy for the raw materials to be stirred when rotating; And when the filter core 13 extends into the raw material, the impurities in the raw material can be filtered on the filter core 13, and by gathering the filter core 13 together, the resistance between the raw material and the extension rod 12 and the filter core 13 during rotation is increased, thereby improving the original stirring efficiency and effect during separation, making it easier for impurities to be separated in the inner lining filter cartridge 4, ensuring the crystallization effect of the raw material after separation.

[0025] Different from the prior art, the present application discloses a rapid crystallization device for clindamycin phosphate. By using the corresponding structures, the raw materials between the inner liner filter cartridge 4 and the locking block 21 can be separated through the inner liner filter cartridge 4, while the impurities can be retained in the inner liner filter cartridge 4, which is easy to separate and filter the raw materials, ensuring the subsequent raw material crystallization efficiency and effect. The separated raw materials can be stored at the bottom of the inner cavity of the crystallization cylinder 2, and at the same time, they are heated by heat conduction through the second diverter cone block 6, so that the separated raw materials can be crystallized in the crystallization cylinder 2, and at the same time, they are heated by the first diverter cone block 6. The conical cross-sections of the blocks 5 and the second diverter cone block 6 facilitate the diffusion of the raw materials toward the outside of the first diverter cone block 5 and the second diverter cone block 6 during separation and subsequent crystallization, thereby avoiding the accumulation of the raw materials. When the filter element 13 extends into the raw materials, the impurities in the raw materials can be filtered on the filter element 13. By gathering the filter elements 13 together, the resistance between the raw materials and the extension rod 12 and the filter element 13 during rotation is increased, thereby improving the original stirring efficiency and effect during separation, making it easier for impurities to be separated in the inner lining filter cartridge 4, thereby ensuring the crystallization effect of the raw materials after separation.

[0026] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A rapid crystallization device for clindamycin phosphate, comprising a base (1), characterized in that: The base (1) is provided with a separation crystallization component; The separation crystallization assembly comprises a crystallization cylinder (2) arranged on the top of the base (1), a heating cylinder (3) is sleeved on the top of the crystallization cylinder (2), a sealing ring is arranged between the crystallization cylinder (2) and the heating cylinder (3), and an inner lining filter cylinder (4) is arranged in the middle of the heating cylinder (3); A first diverter cone block (5) is arranged in the middle of the inner lining filter cartridge (4), a second diverter cone block (6) is arranged at the bottom of the first diverter cone block (5), the second diverter cone block (6) is mounted on the bottom of the inner cavity of the crystallization cylinder (2) by means of bolts, and the first diverter cone block (5) is rotatably connected to the second diverter cone block (6), and the vertical cross-section shapes of the first diverter cone block (5) and the second diverter cone block (6) are arranged to be conical; A support plate (8) is arranged at the top of the inner cavity of the liner filter cartridge (4), a traction plate (10) which is adjustable up and down is arranged at the bottom of the support plate (8), a plurality of extension rods (12) which are adjustable in angle are arranged on the outside of the traction plate (10), and a filter core (13) for filtering is arranged at the bottom of each extension rod (12).

2. The rapid crystallization device of clindamycin phosphate according to claim 1, characterized in that: A limit seat (7) is arranged on the top of the support plate (8), and a rotating rod (9) is rotatably connected to the middle of the limit seat (7). The rotating rod (9) passes through the support plate (8) and extends to the middle of the traction plate (10).

3. The rapid crystallization device of clindamycin phosphate according to claim 2, characterized in that: The rotating rod (9) is threadedly connected to the traction plate (10), and the top of the extension rod (12) extends to the bottom of the support plate (8) and is hinged to the support plate (8).

4. The rapid crystallization device of clindamycin phosphate according to claim 1, characterized in that: A plurality of axle pin seats (18) are fixedly provided on the outer side of the traction plate (10), and each of the axle pin seats (18) is hingedly connected to axle pin members (11). The plurality of axle pin members (11) respectively extend to corresponding extension rods (12) and are hingedly connected to the extension rods (12).

5. The rapid crystallization device of clindamycin phosphate according to claim 2, characterized in that: A sealing cover (14) is provided at the top of the crystallization cylinder (2), a hinge frame (15) is hingedly connected to the sealing cover (14), a connecting cover (16) is fixedly provided at one end of the hinge frame (15), and a temperature sensor (25) extending into the crystallization cylinder (2) is provided on one side of the connecting cover (16).

6. The rapid crystallization device of clindamycin phosphate according to claim 5, characterized in that: The connecting cover (16) is snap-connected with the sealing cover (14), and a handle (17) is rotatably connected to the connecting cover (16). The handle (17) extends to the top end of the rotating rod (9), and the limiting seat (7) and the supporting plate (8) are both mounted on the sealing cover (14).

7. The rapid crystallization device of clindamycin phosphate according to claim 1, characterized in that: A rotating disk (19) is fixedly arranged at the bottom of the first flow dividing cone block (5), a plurality of boosting cross bars (20) are distributed on the outer side of the rotating disk (19), and the lining filter cartridge (4) is mounted on the rotating disk (19).

8. The rapid crystallization device of clindamycin phosphate according to claim 1, characterized in that: A locking block (21) is provided at the top end of the first diverter cone block (5), and a driving motor (24) is mounted at the bottom of the crystallization cylinder (2) via bolts.

9. The rapid crystallization device of clindamycin phosphate according to claim 8, characterized in that: The output end of the drive motor (24) passes through the crystallization cylinder (2) and the second diverter cone block (6) in sequence and extends to the bottom end of the locking block (21), and the output end of the drive motor (24) is rotatably connected to the crystallization cylinder (2) and the second diverter cone block (6).

10. The rapid crystallization device of clindamycin phosphate according to claim 1, characterized in that: A plurality of support legs (22) are distributed on the outside of the crystallization cylinder (2), and each of the support legs (22) is mounted on the outside of the lining filter cylinder (4) by means of bolts. A discharge pipe (23) is provided at the bottom of the crystallization cylinder (2).

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