Sample processing device

Abstract

The invention provides a sample treatment device, and relates to the technical field of medical equipment, the sample treatment device comprises a turntable assembly, a puncture positioning assembly and a sample unloading assembly which are arranged on a wallboard, the turntable assembly comprises a turntable, a plurality of accommodating cavities are circumferentially formed in the turntable and are used for accommodating sampling tubes, and the puncture positioning assembly and the sample unloading assembly are respectively positioned on one side of the turntable; the rotating disc rotates to drive the sampling pipe to rotate to stations corresponding to the puncture positioning assembly and the sample unloading assembly respectively, the puncture positioning assembly performs puncture sampling on the sampling pipe, and the sample unloading assembly unloads the sampling pipe from the rotating disc. The multiple containing cavities are formed in the rotating disc, related operation can be carried out on the multiple sampling pipes at the same time, all the processes of sample pretreatment are completed through driving of the rotating disc, the sample treatment efficiency is improved, and meanwhile the limited design space is met. The whole device is stable in structure and ensures the reliability of sample treatment. The full-flow operation of small-scale batch sample loading, uniform mixing, sampling and sample unloading is realized, and the sample processing efficiency and reliability are improved.

Description

Technical Field

[0001] The present application relates to the technical field of medical equipment and devices, and in particular to a sample processing device. Background Art

[0002] In traditional portable sample analyzers, samples are usually loaded by automatic loading instruments or manual injection. Among them, the sample processing device of the automatic loading instrument is often complex in structure, occupies a large space, or is exposed outside the machine, which is difficult to apply to small sample analyzers; and manual loading requires that the blood sample be fully mixed before blood testing, and then tested with the instrument. Manual single-tube sampling is inefficient and complicated to operate. A single injection workstation cannot meet the requirements of continuous sampling, and it is difficult to apply to emergency scenarios. Summary of the invention

[0003] The purpose of the embodiments of the present application is to provide a sample processing device that can realize the full process operation of small-batch loading, mixing, sampling and unloading, thereby improving the efficiency and reliability of sample processing.

[0004] On the one hand, an embodiment of the present application provides a sample processing device, including a turntable assembly, a puncture positioning assembly and a sample unloading assembly arranged on a wall panel, the turntable assembly including a turntable, a plurality of accommodating cavities circumferentially arranged on the turntable for accommodating sampling tubes, the puncture positioning assembly and the sample unloading assembly are respectively located on one side of the turntable, the turntable rotates and drives the sampling tube to rotate to the workstations corresponding to the puncture positioning assembly and the sample unloading assembly, the puncture positioning assembly punctures and samples the sampling tube, and the sample unloading assembly unloads the sampling tube from the turntable.

[0005] Optionally, the turntable assembly includes a motor and a core shaft connected to the motor, and the core shaft is connected to the turntable.

[0006] Optionally, the turntable assembly further includes a first retaining ring and a second retaining ring, wherein the first retaining ring and the second retaining ring are arranged opposite to each other and are enclosed together with the sample unloading assembly on the outer peripheral wall of the turntable to cover the cavity opening of the accommodating cavity.

[0007] Optionally, an injection port is provided on the first retaining ring, and the injection port is communicated with a containing cavity close to the injection port.

[0008] Optionally, the puncture positioning assembly includes a mounting plate fixed on the wall panel, and a limit block fixed to the mounting plate, the mounting plate extends from the wall panel to the outer periphery of the turntable and the disk surface of the turntable away from the wall panel, and forms a bending portion on the disk surface of the turntable, the limit block is fixed on the bending portion and is located between the bending portion and the turntable, and an elastic member is also arranged between the mounting plate and the limit block.

[0009] Optionally, a puncture hole is formed on the end surface of the mounting plate facing the accommodating cavity, and the puncture hole is communicated with the accommodating cavity.

[0010] Optionally, the sample unloading assembly includes a base fixed on the wall panel, a slide rail and a motor are provided on the base, the motor is connected to a slider, the slider is cooperatively connected to the slide rail, and a movable door is provided on the slider so that the movable door moves along the slide rail. The direction in which the movable door moves along the slide rail is perpendicular to the surface of the turntable, and the movable door corresponds to the cavity opening of the accommodating cavity at the bottom of the turntable.

[0011] Optionally, it also includes a detection component, which is respectively located in the accommodating chamber near the injection port to detect whether the sampling tube is in place, the accommodating chamber near the unloading assembly to detect whether the sampling tube has completed unloading, and the accommodating chamber at the bottom of the turntable to detect whether the turntable is accurately positioned.

[0012] Optionally, the detection component includes an optical coupler or an optical sensor.

[0013] Optionally, a controller is also included, and the controller is electrically connected to the detection component, the turntable component, the sample unloading component, and the puncture positioning component respectively.

[0014] The sample processing device provided by the embodiment of the present application has a turntable assembly, a puncture positioning assembly and a sample unloading assembly arranged on the wall panel. The turntable assembly includes a turntable, and a plurality of accommodating cavities are arranged on the circumference of the turntable for accommodating sampling tubes. The puncture positioning assembly and the sample unloading assembly are respectively located on one side of the turntable. The turntable rotates and drives the sampling tube to rotate to the workstations corresponding to the puncture positioning assembly and the sample unloading assembly respectively. The puncture positioning assembly punctures and samples the sampling tube, and the sample unloading assembly unloads the sampling tube from the turntable. The sample can be injected, shaken, sampled and unloaded. The device is provided with a sample puncture position, and the sample can be punctured and sucked with the puncture positioning assembly. After the sample is processed, the sample unloading function can be performed. The setting of multiple accommodating cavities on the turntable can perform related operations on multiple sampling tubes at the same time. All processes of sample pre-processing are completed by the turntable drive to improve the efficiency of sample processing and meet the limited design space. And the structure of the whole device is stable, which can ensure the reliability of sample processing. It realizes the whole process of small batch loading, mixing, sampling and unloading, and improves the efficiency and reliability of sample processing. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments of the present application will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0016] Figure 1 This is one of the schematic diagrams of the structure of the sample processing device provided in this embodiment;

[0017] Figure 2 This is the second structural schematic diagram of the sample processing device provided in this embodiment;

[0018] Figure 3 This is the third structural schematic diagram of the sample processing device provided in this embodiment.

[0019] Icons: 10-wall panel; 11-turntable; 110-accommodating cavity; 111-groove; 112-first retaining ring; 113-second retaining ring; 114-cavity opening; 115-inlet; 116-core shaft; 117-noise reduction member; 118-motor; 120-motor; 121-slide rail; 122-moving door; 123-base; 130-mounting plate; 130a-puncture port; 131-bending part; 132-limiting block; 141-injection detection assembly; 142-unloading detection assembly; 142a-optical coupling plate; 142b-optical coupling; 142c-optical coupling baffle; 143-sample positioning assembly; 20-sampling tube. DETAILED DESCRIPTION

[0020] The technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application.

[0021] In the description of this application, it should be noted that the terms "inside", "outside", etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, or the orientation or positional relationship in which the product of the application is usually placed when in use, which is only for the convenience of describing this application and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this application. In addition, the terms "first", "second", etc. are only used to distinguish the description, and cannot be understood as indicating or implying relative importance.

[0022] It should also be noted that, unless otherwise clearly specified and limited, the terms "disposed" and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a direct connection, or an indirect connection through an intermediate medium, or it can be the internal communication of two elements. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0023] Based on the limitations of current sample analyzers in applicable scenarios such as sample loading and mixing, an embodiment of the present application provides a sample processing device that occupies a small space, has a simple structure, and accurate positioning, and can realize functions such as small-scale batch automatic sample loading, mixing, puncture positioning, and sample unloading.

[0024] For details, please refer to Figure 1 As shown, an embodiment of the present application provides a sample processing device, including: a turntable assembly, a puncture positioning assembly and a sample unloading assembly arranged on a wall panel 10, the turntable assembly includes a turntable 11, and a plurality of accommodating cavities 110 are circumferentially arranged on the turntable 11 for accommodating a sampling tube 20, the puncture positioning assembly and the sample unloading assembly are respectively located on one side of the turntable 11, the turntable 11 rotates, driving the sampling tube 20 to rotate to the workstations corresponding to the puncture positioning assembly and the sample unloading assembly, the puncture positioning assembly punctures and samples the sampling tube 20, and the sample unloading assembly unloads the sampling tube 20 from the turntable 11.

[0025] The sampling tube 20 is arranged in the accommodating cavity 110 of the turntable 11. There are multiple accommodating cavities 110, which are arranged along the circumference of the turntable 11, and one sampling tube 20 is arranged in one accommodating cavity 110. For example, the turntable 11 is a circular turntable 11, and the sampling tube 20 is located in the accommodating cavity 110. The multiple sampling tubes 20 are arranged in a circle circumferentially on the turntable 11, and each sampling tube 20 is arranged radially, and the bottom of each sampling tube 20 points to the center of the turntable 11. When the turntable 11 rotates, the multiple sampling tubes 20 are driven to rotate, so as to achieve the effect of shaking the multiple sampling tubes 20 at the same time.

[0026] When the turntable 11 rotates to different positions, the same sampling tube 20 can be in different positions. The puncture positioning assembly and the sample unloading assembly are respectively located on one side of the turntable 11 and correspond to the cavity 114 of the accommodating cavity 110, so that when the sampling tube 20 rotates with the turntable 11 to the puncture position corresponding to the puncture positioning assembly, the sampling tube 20 is punctured by the puncture positioning assembly; when the sampling tube 20 rotates to the sample unloading position corresponding to the sample unloading assembly, the sample unloading assembly unloads the sampling tube 20 from the turntable 11, thereby completing an operation cycle.

[0027] The sample processing device provided in the embodiment of the present application can realize sample injection, shaking, sampling and sample unloading. The device is provided with a sample puncture position, which can perform functions such as puncturing and aspirating samples in conjunction with the puncture positioning component. The sample unloading function can be performed after the sample processing is completed.

[0028] The arrangement of multiple accommodating chambers 110 on the turntable 11 allows for the simultaneous operation of multiple sampling tubes 20, and all sample pre-processing processes (including sample injection, transportation, rotation and shaking, puncture sampling, and sample unloading) are completed through the drive of the turntable 11, so as to improve the efficiency of sample processing while meeting the limited design space. The entire device has a stable structure, which can ensure the reliability of sample processing.

[0029] In some embodiments, Figure 2 As shown, the sample processing device is fixed on the wall panel 10 as a whole, and the turntable assembly includes a motor 118 and a core shaft 116. The core shaft 116 passes through the wall panel 10 and is connected to the motor 118. The core shaft 116 is also fixedly connected to the turntable 11. The motor 118 drives the turntable 11 to rotate through the core shaft 116, so that the sampling tube 20 in the turntable 11 rotates to different positions.

[0030] The turntable assembly also includes a first retaining ring 112 and a second retaining ring 113, which are relatively enclosed on the outer peripheral wall of the turntable 11, and can cover the cavity opening 114 of the accommodating cavity 110 of the turntable 11 to prevent the sampling tube 20 in the cavity opening 114 from slipping out of the accommodating cavity 110 under the action of gravity and centrifugal force.

[0031] Among them, the first retaining ring 112 is arranged on one side of the turntable 11 and is fixedly connected to the wallboard 10. The first retaining ring 112 is provided with a sample inlet 115, and the sample inlet 115 is correspondingly connected to the accommodating cavity 110 located at the sample inlet position on the turntable 11, and the sampling tube 20 enters the accommodating cavity 110 of the turntable 11 through the sample inlet 115. The second retaining ring 113 is arranged on the other side of the turntable 11 and is also fixed to the wallboard 10. A noise reduction member 117, such as noise reduction cotton, is also arranged inside the second retaining ring 113, that is, between the second retaining ring 113 and the turntable 11, which is used to reduce the noise generated by the collision between the sampling tube 20 and the second retaining ring 113 during the rotation and shaking process.

[0032] The puncture positioning assembly is located directly above the turntable 11, and the puncture positioning assembly includes a mounting plate 130, a limit block 132 and a plurality of elastic members, such as a spring. The spring is located between the mounting plate 130 and the limit block 132, and one end of the spring is fixed to the mounting plate 130 and the other end is fixed to the limit block 132.

[0033] The mounting plate 130 is fixed on the wall panel 10. The mounting plate 130 extends to the turntable 11 and forms a bent portion 131 on the side of the turntable 11 away from the wall panel 10. The mounting plate 130 is located at the upper end of the outer peripheral wall of the turntable 11 and a puncture hole 130a is opened. The puncture hole 130a is connected to the cavity 114 of the turntable 11. The limit block 132 is located between the disk surface of the turntable 11 away from the wall panel 10 and the bent portion 131 of the mounting plate 130. The limit block 132 is connected to the bent portion 131 of the mounting plate 130, and a groove 111 is formed on the disk surface of the turntable 11 at the position of the limit block 132.

[0034] Due to the setting of the groove 111, the accommodating chamber 110 forms a semi-closed structure at the position of the groove 111. In the natural state, under the compression force of the spring, a limiting space is formed between the limiting block 132 and the groove 111. The limiting space can be understood as the upper end part of the accommodating chamber 110 close to the outer peripheral wall of the turntable 11. The inner diameter of the limiting space in the direction perpendicular to the turntable 11 is smaller than the inner diameter in the direction parallel to the turntable 11, that is, the cross-section of the limiting space forms a long strip in the radial direction of the turntable 11, which is adapted to the shape of the sampling tube 20. The limiting block 132 can limit the sampling tube 20 within the limiting space.

[0035] When the sampling tube 20 reaches the puncture position through the rotation of the turntable 11, the spring located between the mounting plate 130 and the limit block 132 will continuously generate a compressive force on the tube cap of the sampling tube 20, so that the sampling tube 20 is stable at the puncture position without shaking, and the mounting plate 130 forms a puncture opening 130a on the end face facing the accommodating chamber 110, and the puncture opening 130a is connected to the accommodating chamber 110, so that the puncture needle can pass through the puncture opening 130a to pierce the sampling tube 20 in the accommodating chamber 110 for puncture sampling operation.

[0036] The sample unloading assembly is located on the outer periphery of the turntable 11 and below the first retaining ring 112 . The first retaining ring 112 , the sample unloading assembly and the second retaining ring 113 form an annular structure, which is blocked on the outer peripheral wall of the turntable 11 to prevent the sampling tube 20 in the turntable 11 from slipping out of the turntable 11 .

[0037] Specifically, refer to Figure 3 As shown, the sample unloading assembly is located at the bottom of the turntable 11, and includes a base 123, which is fixed on the wall panel 10, a slide rail 121 and a motor 120 are fixed on the base 123, a slider is adapted on the slide rail 121, the motor 120 is connected to the slider, and a movable door 122 is fixed on the slider or is integrally arranged with the slider. When the motor 120 rotates, the movable door 122 is driven to move on the slide rail 121, and the direction in which the movable door 122 moves along the slide rail 121 is perpendicular to the direction of the turntable 11, and the movable door 122 corresponds to the cavity 114 of the accommodating cavity 110 at the bottom of the turntable 11.

[0038] In this way, when the movable door 122 moves, it can block the cavity opening 114 of the sample unloading position accommodating cavity 110 of the turntable 11 or move away from the cavity opening 114. In the non-unloading state, the movable door 122 blocks the cavity opening 114 of the accommodating cavity 110; when the sample needs to be unloaded, the movable door 122 moves away from the cavity opening 114 of the accommodating cavity 110, and the cavity opening 114 is not blocked at this time, and the sampling tube 20 in the cavity opening 114 can slide out of the cavity opening 114 by gravity. The lower part of the sample unloading position corresponds to the waste tube bin, and the sampling tube 20 naturally slides into the waste tube bin after sliding out.

[0039] On the other hand, the sample processing device is also provided with a plurality of detection components. According to different setting positions, the detection components include a sample introduction detection component 141 , a sample unloading detection component 142 and a sample positioning component 143 .

[0040] The sampling detection assembly 141 is fixed on the wall panel 10 and is located at the upper end of the cavity 114 of the rotating disk 11 accommodating cavity 110 closest to the sampling port 115, and is used to detect whether the sampling tube 20 is properly injected and whether the sampling tube 20 exceeds the specified length.

[0041] The sample unloading detection component 142 is disposed on the base 123 of the sample unloading component. The base 123 is fixed on the wall panel 10 and is located at the upper end of the cavity opening 114 closest to the sample unloading position accommodating cavity 110 for detecting whether the sampling tube 20 is unloaded.

[0042] The sample positioning assembly 143 is located at the upper end of the cavity opening 114 of the accommodating cavity 110 at the bottom of the turntable 11 , and is fixed on the wall panel 10 , and is used for accurate positioning of the turntable 11 .

[0043] The detection component may specifically be an optical coupler 142b or an optical sensor. Figure 3 As shown, taking the sample unloading detection component 142 as an example, an optical coupling plate 142a is provided on the base 123, and an optical coupler 142b is provided on the optical coupling plate 142a. An optical coupling baffle 142c is connected to the movable door 122 of the sample unloading component, so that the optical coupling baffle 142c can move with the movable door 122. When the movable door 122 blocks the cavity opening 114 of the accommodating cavity 110 at the sample unloading position, the optical coupling 142b baffle is located in the optical coupling 142b. When the movable door 122 is moved away to expose the cavity opening 114 of the accommodating cavity 110 for sample unloading, the optical coupling baffle 142c moves with the movable door 122 and is removed from the optical coupling 142b. At this time, the optical coupling 142b gives a signal to the controller, indicating that the sample unloading is completed. The detection components at other positions are executed with reference to the above, and no further description is given.

[0044] The sample processing device also includes a controller, which is electrically connected to the detection component, the motor 118 of the turntable component, the motor 120 of the sample unloading component, the puncture positioning component, etc., so as to automatically control, automatically detect, automatically puncture, etc. the entire sample processing device, realize automation of operation, and improve operation efficiency and response accuracy.

[0045] In summary, in the sample processing device provided by the embodiment of the present application, when injecting a sample, the sampling tube 20 is put in from the injection port 115 of the first retaining ring 112, passes through the cavity 114 of the turntable 11 to reach the accommodating cavity 110, and the turntable 11 is rotated by the motor 118 of the turntable assembly and the sample in the sampling tube 20 is shaken evenly. Since the sample unloading assembly and the first retaining ring 112 and the second retaining ring 113 form an annular structure and surround the outer peripheral wall of the turntable 11, blocking the cavity 114, the sampling tube 20 will not slide down under the action of gravity and centrifugal force, and the turntable 11 drives the sampling tube 20 to rotate and mix evenly. After rotating several times, the sampling tube 20 reaches the puncture position, and the sampling tube 20 is fixed in the set position by the limit block 132 of the puncture positioning assembly. The puncture needle passes through the puncture port 130a on the mounting plate 130, and punctures the sampling tube 20 for sampling.

[0046] When unloading samples, the motor 118 drives the turntable 11 to rotate, and the sampling tube 20 reaches the unloading position. The motor 120 of the unloading assembly drives the slider and the movable door 122 fixed on the slider, so that the movable door 122 moves in the direction perpendicular to the surface of the turntable 11, away from the turntable 11, and the cavity 114 located at the unloading position is not blocked by the movable door 122. The sampling tube 20 naturally slides from the accommodating cavity 110 into the waste tube bin by gravity. The sample processing device of the present application can simultaneously perform steps such as injection, puncture, and shaking while unloading samples, greatly improving the sample processing efficiency. A high degree of integration is achieved through the stacking design of multiple accommodating cavities 110 on the turntable 11, and all processes of sample pre-processing (including injection, transportation, rotation and shaking, puncture sampling and unloading) are completed through the turntable assembly with a streamlined structure and drive, while meeting the limited design space.

[0047] Through the sample processing device provided in the above-mentioned embodiment of the present application, the sampling tube 20 is injected, transported, shaken, cached, and unloaded, and the process is more concise. Through the cooperation of the turntable 11 and the retaining ring, the requirements of external injection and internal rotation of the test tube can be realized, and the structure is more flexible and space-saving. At the same time, the motion stability is improved. The stable movement of the device is also achieved through the precise motor 118 drive and the limit block 132. The sample processing device provided in the embodiment of the present application improves the reliability and efficiency of sample processing while ensuring the stability of its operating state; in the case of limited space, various functions of the full process of sample processing are realized, the performance of the immunoassay analyzer is significantly improved, and a wider range of application needs are met.

[0048] The above description is only an embodiment of the present application and is not intended to limit the protection scope of the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A sample processing device, characterized in that: include: A turntable assembly, a puncture positioning assembly and a sample unloading assembly are arranged on the wall panel, wherein the turntable assembly includes a turntable, and a plurality of accommodating cavities are circumferentially arranged on the turntable for accommodating sampling tubes. The puncture positioning assembly and the sample unloading assembly are respectively located on one side of the turntable. The turntable rotates and drives the sampling tube to rotate to the workstations corresponding to the puncture positioning assembly and the sample unloading assembly respectively. The puncture positioning assembly punctures and samples the sampling tube, and the sample unloading assembly unloads the sampling tube from the turntable.

2. The sample processing device according to claim 1, characterized in that: The turntable assembly includes a motor and a core shaft connected to the motor, and the core shaft is connected to the turntable.

3. The sample processing device according to claim 2, characterized in that: The turntable assembly further includes a first retaining ring and a second retaining ring, wherein the first retaining ring and the second retaining ring are arranged opposite to each other and are enclosed together with the sample unloading assembly on the outer peripheral wall of the turntable to cover the cavity opening of the accommodating cavity.

4. The sample processing device according to claim 3, characterized in that: The first retaining ring is provided with an injection port, and the injection port is communicated with the accommodating cavity close to the injection port.

5. The sample processing device according to claim 1, characterized in that: The puncture positioning assembly includes a mounting plate fixed on the wall panel, and a limit block fixed to the mounting plate, the mounting plate extends from the wall panel to the outer periphery of the turntable and the disk surface of the turntable away from the wall panel, and forms a bending portion at the disk surface of the turntable, the limit block is fixed on the bending portion and is located between the bending portion and the turntable, and an elastic member is also arranged between the mounting plate and the limit block.

6. The sample processing device according to claim 5, characterized in that: A puncture hole is formed on the end surface of the mounting plate facing the accommodating cavity, and the puncture hole is communicated with the accommodating cavity.

7. The sample processing device according to claim 1, characterized in that: The sample unloading assembly includes a base fixed on the wall panel, a slide rail and a motor are arranged on the base, the motor is connected with a slider, the slider is cooperatively connected with the slide rail, a movable door is arranged on the slider so that the movable door moves along the slide rail, the direction in which the movable door moves along the slide rail is perpendicular to the surface of the turntable, and the movable door corresponds to the cavity opening of the accommodating cavity at the bottom of the turntable.

8. The sample processing device according to any one of claims 1 to 7, characterized in that: It also includes a detection component, which is respectively located in the accommodating chamber near the injection port to detect whether the sampling tube is in place, the accommodating chamber near the unloading assembly to detect whether the sampling tube has completed unloading, and the accommodating chamber at the bottom of the turntable to detect whether the turntable is accurately positioned.

9. The sample processing device according to claim 8, characterized in that: The detection component includes an optical coupler or an optical sensor.

10. The sample processing device according to claim 8, characterized in that: It also includes a controller, which is electrically connected to the detection component, the turntable component, the sample unloading component, and the puncture positioning component respectively.

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