Urine filtering device and urine filtering method

Abstract

The invention provides a urine filtering device and a urine filtering method.The urine filtering device comprises a first barrel body and a second barrel body, one end of the first barrel body and one end of the second barrel body are set to be first opening ends, and the other ends of the first barrel body and the second barrel body can be communicated with the atmosphere; the first can body and the second can body are provided with sliding grooves. The baffle and the filter screen can penetrate through the side walls of the first barrel body and the second barrel body from the outer sides of the first barrel body and the second barrel body along the sliding grooves to extend into the first barrel body or the second barrel body, and the baffle and the filter screen divide the first barrel body or the second barrel body into two independent cavities respectively; the two pistons are respectively matched with the inner walls of one sides of the first opening ends of the first barrel body and the second barrel body. According to the device, a large amount of manual operation is avoided, the urine sample treatment efficiency is higher, and the operation is simpler and quicker; the treatment of the urine sample is completed at the detected person, so that an experimenter for subsequent detection does not need to be in contact with the urine, and the disgusting of the experimenter is avoided.

Description

Technical Field

[0001] The present application relates to the technical field of medical equipment, and in particular to a urine filtering device and a urine filtering method. Background Art

[0002] Bladder cancer refers to a malignant tumor that occurs on the bladder mucosa. It is the most common malignant tumor of the urinary system and one of the top ten common tumors in the body. It ranks first in the incidence of genitourinary tumors in my country, and its incidence in the West is second only to prostate cancer.

[0003] About 90% of bladder cancer patients have hematuria as their initial clinical manifestation, which is usually painless, intermittent, and visible throughout the entire process, and sometimes microscopic hematuria. For patients over 40 years old with painless macroscopic hematuria, the possibility of urinary tract tumors, especially bladder cancer, should be considered. At this time, it is generally necessary to prepare a sample for methylation detection from the patient's urine residue and perform the corresponding test.

[0004] In the prior art, the collection of methylation detection samples for bladder cancer is obtained by centrifuging urine. Generally, after obtaining the urine sample of the subject, the urine sample is transferred into a centrifuge tube. After centrifugation, the urine sample is stratified. A pipette is used to take the urine residue, and the urine residue is diluted with a diluent to prepare a methylation detection sample. However, the preparation process of the above-mentioned methylation detection sample is cumbersome; the handling of urine is unhygienic, easy to pollute the laboratory environment, and easy to cause disgust to the experimenters; the efficiency of sample pre-treatment is low. Summary of the invention

[0005] In order to solve the problems in the prior art, the present application provides a urine filtering device and a urine filtering method using the urine filtering device. The technical solution of the present application is as follows:

[0006] 1. A urine filtering device, comprising:

[0007] A first barrel body and a second barrel body, wherein one end of the first barrel body and the second barrel body is set as a first open end, and the other end can be communicated with the atmosphere; and the first barrel body and the second barrel body are provided with a slide groove;

[0008] A baffle and a filter screen, wherein the baffle and the filter screen can extend from the outside of the first barrel body and the second barrel body through the side walls thereof along the chute into the first barrel body or the second barrel body, and respectively divide the first barrel body or the second barrel body into two independent chambers;

[0009] Two pistons are respectively matched with the inner wall of one side of the first opening end of the first barrel body and the second barrel body.

[0010] 2. The urine filtration device according to item 1, wherein:

[0011] The other end of the first barrel body and / or the second barrel body is configured as a second open end;

[0012] The urine filtering device also includes:

[0013] A cover body, wherein the cover body is matched with the second open end of the first barrel body and / or the second barrel body; and an air hole is arranged on the cover body.

[0014] 3. The urine filtration device as described in item 1, wherein the equivalent circular diameter of the pores is less than 4 mm.

[0015] 4. The urine filtering device according to item 1, wherein the baffle comprises:

[0016] Baffle body;

[0017] a first sealing ring, which is disposed on the baffle body and is used to seal the baffle body and the inner wall of the first barrel body or the second barrel body when the baffle is inserted into the slide groove;

[0018] The first pulling portion is arranged on the baffle body and is used for pulling the baffle body.

[0019] 5. The urine filtering device according to item 1, wherein the filter screen comprises:

[0020] Frame;

[0021] A filter body, wherein the filter body is laid on the frame;

[0022] a second sealing ring, which is disposed on the frame body and is used to seal the frame body and the inner wall of the first barrel body or the second barrel body when the filter screen is inserted into the chute;

[0023] The second pull-out portion is arranged on the frame body and is used for pulling out the frame body.

[0024] 6. The urine filtration device according to item 5, wherein the pore size of the filter body is 1 to 200 nm.

[0025] 7. The urine filtering device as described in item 5, wherein the filter screen further comprises: a support body, wherein the support body is arranged on the frame body and located at the bottom of the filter screen body to support the filter screen body.

[0026] 8. The urine filtration device as described in item 7, wherein the support body is a load-bearing net.

[0027] 9. The urine filtering device as described in item 1, wherein the piston comprises: a piston body, the piston body being capable of cooperating with the inner wall of one side of the first open end of the first barrel body and the second barrel body; and a piston rod, one end of which is connected to the piston body.

[0028] 10. The urine filtration device as described in item 1, wherein the urine filtration device further comprises: a connecting piece, wherein the connecting piece connects the first barrel body 11 and the second barrel body 12.

[0029] 11. The urine filtration device as described in item 1, wherein the urine filtration device further comprises: a handle, and the handle is arranged on the first barrel body and / or the second barrel body.

[0030] 12. A method for filtering urine, comprising filtering urine using the urine filtering device described in any one of items 1 to 11, wherein:

[0031] The first opening ends of the first barrel body and the second barrel body face downward; the filter screen extends into the first barrel body through the slide groove of the first barrel body to divide the first barrel body into a first upper chamber and a first lower chamber; the baffle extends into the second barrel body through the slide groove of the second barrel body to divide the second barrel body into a second upper chamber and a second lower chamber;

[0032] One of the pistons extends into the first lower chamber; the other piston seals the first open end of the second barrel to store the diluent in the second lower chamber;

[0033] The method comprises:

[0034] The sample adding and filtering step comprises: adding a urine sample into the first upper chamber, and downwardly pulling a piston inserted into the first lower chamber, so that the urine sample is sucked from the first upper chamber into the first lower chamber, and urine residues are intercepted on the upper part of the filter;

[0035] The replacement step includes: exchanging the positions of the filter screen and the baffle plate, and keeping the side of the filter screen that intercepts urine residues facing upward;

[0036] The dilution step pushes the piston sealing the first open end of the second barrel body to press the diluent from the second lower chamber into the second upper chamber, and the diluent flushes the urine residue on the filter screen and dilutes the urine residue.

[0037] The present application provides a novel device for preparing samples for methylation detection, which can process urine samples more simply and quickly to prepare samples for methylation detection. Only three steps, namely, "sample addition and filtration step", "transposition step" and "dilution step" are required to complete the collection and processing of urine samples. Moreover, the device allows the processing of urine samples to be completed at the person being tested, thus avoiding laboratory environmental pollution. Experimental personnel who conduct subsequent tests do not need to come into contact with urine, thus not causing disgust to the experimental personnel. At the same time, a large amount of manual operation is avoided. The device of the present application makes the processing efficiency of urine samples higher. When a second barrel body and corresponding slide grooves and baffles are provided, the diluent can be well retained in the second lower chamber before the urine sample is processed, so that the urine sample can be processed in time after it is obtained; when a cover body with air holes is provided, it is not only convenient to push and pull the piston, but also convenient to add and remove the diluted methylation detection sample from the urine sample; when a baffle with a first sealing ring is provided, it can ensure better preservation of the diluent and prevent the diluted methylation detection sample from flowing back to the second lower chamber; when a filter screen with a second sealing ring is provided, it can ensure that all urine samples can be filtered through the filter screen to ensure the filtering effect.

[0038] The above description is only an overview of the technical solution of the present application. In order to make the technical means of the present application clearer and to enable those skilled in the art to implement it according to the contents of the specification, and to make the above and other purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are exemplified below. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] Figure 1 : A schematic diagram of the structure of a urine filtering device;

[0040] Figure 2 : Schematic diagram of cover structure;

[0041] Figure 3 : Schematic diagram of the cross-sectional structure of the first barrel and the second barrel;

[0042] Figure 4 : Schematic diagram of baffle structure;

[0043] Figure 5 : Schematic diagram of the upper structure of the filter;

[0044] Figure 6 : Schematic diagram of the lower structure of the filter;

[0045] Figure 7 : Schematic diagram of piston structure.

[0046] Description of reference numerals:

[0047] 11. first barrel body; 11-1. first upper chamber; 11-2. first lower chamber; 12. second barrel body; 12-1. second upper chamber; 12-2. second lower chamber; 13. first opening end; 14. slide groove; 15. second opening end; 16. cover body; 16-1. air hole; 16-2. protrusion; 17. handle; 18. connector;

[0048] 20. baffle; 21. baffle body; 22. first sealing ring; 23. first pull-out portion;

[0049] 30. filter screen; 31. frame; 32. filter screen body; 33. second sealing ring; 34. second pull-out portion; 35. support body;

[0050] 40. Piston; 41. Piston body; 42. Piston rod. DETAILED DESCRIPTION

[0051] The following embodiments of the present application are only used to illustrate the specific embodiments of the present application, and these embodiments cannot be understood as limiting the present application. Any other changes, modifications, substitutions, combinations, and simplifications made without departing from the spirit and principle of the present application are deemed to be equivalent replacement methods and fall within the scope of protection of the present application.

[0052] Those skilled in the art should understand that, in the disclosure of the present application, the terms "first", "second", "third", "fourth", "fifth", etc. are only used to distinguish different structures, but do not limit the number, connection relationship, etc. of specific structures; in addition, the directions or positional relationships indicated by "longitudinal", "lateral", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc. are based on the directions or positional relationships shown in the accompanying drawings, which are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation. Therefore, the above terms cannot be understood as limitations on the present application.

[0053] This embodiment provides a urine filtering device, such as Figure 1 As shown, including:

[0054] A first barrel body 11 and a second barrel body 12, wherein one end of the first barrel body 11 and the second barrel body 12 is set as a first open end 13, and the other end can be communicated with the atmosphere; and the first barrel body 11 and the second barrel body 12 are provided with a slide groove 14;

[0055] The baffle 20 and the filter 30 are capable of extending into the first barrel body and the second barrel body from the outside of the first barrel body and the second barrel body through the side walls thereof along the chute 14, and dividing the first barrel body and the second barrel body into two independent chambers respectively;

[0056] Two pistons 40 are respectively matched with the inner wall of one side of the first opening end 13 of the first barrel body 11 and the second barrel body 12 .

[0057] When using the urine filtering device of the present application for urine filtering, the first open end 13 of the first barrel body 11 and the second barrel body 12 needs to face downward; the filter screen 30 extends into the first barrel body 11 through the slide groove 14 of the first barrel body 11 to divide the first barrel body 11 into a first upper chamber 11-1 and a first lower chamber 11-2; the baffle 20 extends into the second barrel body 12 through the slide groove 14 of the second barrel body 12 to divide the second barrel body 12 into a second upper chamber 12-1 and a second lower chamber 12-2; a piston 40 extends into the first lower chamber 11-2; another piston 40 seals the first open end 13 of the second barrel body 12 to store the diluent in the second lower chamber 12-2.

[0058] Afterwards, the urine filtering device of the present application is used to filter urine, which specifically includes:

[0059] The sample adding and filtering step includes: adding a urine sample into the first upper chamber 11-1, and pulling down the piston 40 inserted into the first lower chamber 11-2 to suck the urine sample from the first upper chamber 11-1 into the first lower chamber 11-2, and the urine residue is intercepted on the upper part of the filter screen 30;

[0060] The replacement step includes: exchanging the positions of the filter screen 30 and the baffle 20, and keeping the side of the filter screen 30 that retains urine residue facing upward;

[0061] The dilution step pushes the piston 40 sealing the first open end of the second barrel body 12 to press the diluent from the second lower chamber 12-2 into the second upper chamber 12-1, and the diluent washes down the urine residue on the filter screen 30 and dilutes the urine residue.

[0062] The present application has no specific limitation on the shapes of the first barrel body and the second barrel body, such as a column, a quadrangular pyramid or a cuboid, and in the present embodiment, they are cuboids.

[0063] There is no specific limitation in the present application on the materials of the first barrel body and the second barrel body. In the present embodiment, both the first barrel body and the second barrel body are made of polymer materials.

[0064] The present application has no specific limitation on the volumes of the first barrel body and its first upper chamber, first lower chamber, and the second barrel body and its second upper chamber, second lower chamber, and those skilled in the art can make specific adjustments and designs according to the volume of the urine sample to be processed.

[0065] Therefore, it can be known that the present application provides a new device for preparing samples for methylation detection. Through the above device, urine samples can be processed more simply and quickly to prepare samples for methylation detection, and only three steps are required to complete the collection and processing of urine samples; moreover, the above device enables the processing of urine samples to be completed at the person being tested, avoiding laboratory environmental pollution, and the experimenters conducting subsequent tests do not need to come into contact with urine, so it will not cause disgust to the experimenters; at the same time, since a large number of manual operations are avoided, the above device of the present application makes the processing efficiency of urine samples higher; the second barrel body and the corresponding slide trough and baffle are provided, which can well retain the diluent in the second lower chamber before the urine sample is processed, so that the urine sample can be processed in time after it is obtained.

[0066] In one embodiment, Figure 1 , Figure 2 As shown, the other end of the first barrel body 11 and / or the second barrel body 12 is set as a second open end 15; the urine filtering device also includes: a cover body 16, the cover body 16 is matched with the second open end 15 of the first barrel body 11 and / or the second barrel body 12; and the cover body 16 is provided with an air hole 16-1.

[0067] There is no specific limitation on the material of the cover body in the present application. The cover body 16 in the present embodiment is made of a polymer material.

[0068] In this embodiment, by providing a cover 16 for the first barrel body 11 and the second barrel body 12, it is possible to conveniently add a urine sample into the first upper chamber 11-1 and take out a diluted methylation detection sample from the second upper chamber 12-1. At the same time, a vent hole 16-1 is provided to connect the first upper chamber 11-1 and the second upper chamber 12-1 to the atmosphere, thereby facilitating the pushing and pulling of the piston 40.

[0069] Preferably, the equivalent circular diameter of the air hole is less than 4 mm (such as 1 mm, 2 mm or 3 mm), so as to ensure that the liquid does not flow out while being connected to the atmosphere to maintain the air pressure balance in the first barrel body and the second barrel body.

[0070] It should be noted that the equivalent circle diameter in the present application refers to the diameter of a circle with the same area.

[0071] In addition, if Figure 1 , Figure 2As shown, a protrusion 16-2 may be provided on the cover 16, so that the cover 16 can be easily opened. Of course, a groove may also be provided on the cover 16 to facilitate opening of the cover 16.

[0072] In one embodiment, Figure 4 As shown, the baffle 20 includes:

[0073] Baffle body 21;

[0074] a first sealing ring 22, which is disposed on the baffle body 21 and is used to seal the baffle body 21 and the inner wall of the first barrel body 11 or the second barrel body 12 when the baffle 20 is inserted into the slide groove 14;

[0075] The first pull-out portion 23 is disposed on the baffle body 21 to be used for pulling out the baffle body 21 .

[0076] The present application has no specific restrictions on the location of the first sealing ring 22 on the baffle body 21, as long as it can seal the baffle 20 and the inner wall of the first barrel body 11 or the second barrel body 12, such as being arranged on the upper side, lower side and / or side of the baffle body. In this embodiment, the first sealing ring 22 is arranged around the upper edge of the baffle body 21 (such as Figure 4 shown).

[0077] There is no specific limitation in the present application on the material of the baffle body. The baffle body in the present embodiment is made of polymer material.

[0078] The first pull-out portion 23 is a pull-out handle with a rectangular groove disposed on one side of the baffle body 21 in this embodiment.

[0079] This embodiment provides a specific solution for the baffle 20, which can insert the baffle body 21 into the slide groove 14 through the first pull-out portion 23, and the first sealing ring 22 seals the baffle body 21 and the inner wall of the first barrel body 11 or the second barrel body 12, thereby dividing the first barrel body or the second barrel body into two independent chambers.

[0080] In one embodiment, Figure 5 , Figure 6 As shown, the filter screen 30 includes:

[0081] Frame 31;

[0082] A filter body 32, the filter body 32 is laid on the frame 31; in this embodiment, the filter body 32 is a filter membrane;

[0083] A second sealing ring 33, which is disposed on the frame to seal the frame and the inner wall of the first barrel 11 or the second barrel 12 when the filter 30 is inserted into the chute 14;

[0084] The second drawer 34 is disposed on the frame body 31 to be used for drawing the frame body 31 .

[0085] The present application has no specific restrictions on the location of the second sealing ring 33 on the frame 31, as long as it can seal the frame 31 and the inner wall of the first barrel 11 or the second barrel, such as being arranged on the upper side, lower side and / or side of the frame. Figure 5 as shown) and the lower edge (as Figure 6 ) settings.

[0086] This embodiment provides a specific solution for the filter 30, which can insert the frame 31 into the slide groove 14 through the second pull-out portion 34, and the second sealing ring 33 seals the frame 31 and the inner wall of the first barrel body 11 or the second barrel body 12, thereby dividing the first barrel body 11 or the second barrel body 12 into two independent chambers.

[0087] Regarding the pore size of the filter body 32, those skilled in the art can change the pore size of the filter body according to the diameter of the urine residue to be retained. The proper selection of the pore size of the filter body can ensure that the diluted methylation detection sample prepared by the above-mentioned device is consistent with the diluted methylation detection sample prepared after centrifugation in the prior art. In the present application, the pore size of the filter body is preferably 1 to 200nm (specifically 20nm, 40nm, 60nm, 80nm, 100nm, 120nm, 140nm, 160nm or 180nm). In this embodiment, a filter membrane with a pore size of 8nm is used to filter and obtain urine residues of the required size for the methylation detection sample.

[0088] The second pull-out portion 34 is a pull-out handle with a rectangular groove disposed on one side of the frame body 31 in this embodiment.

[0089] In one embodiment, Figure 5 , Figure 6 As shown, the filter screen 30 further includes: a support body 35 , which is disposed on the frame body 31 and located at the bottom of the filter screen body 32 to support the filter screen body 32 .

[0090] The support 35 supports the filter body 32, so that the filter body 32 will not be broken due to excessive force and will not affect the filtering effect. Figure 6 The grid-like load-bearing net shown.

[0091] In one embodiment, Figure 7 As shown, the piston 40 includes:

[0092] A piston body 41, wherein the piston body 41 can cooperate with the inner wall of the first barrel body 11 and the first opening end 13 of the second barrel body 12; in this embodiment, the piston body 41 is a rubber plug;

[0093] A piston rod 42 , one end of which is connected to the piston body 41 .

[0094] The piston body 41 cooperates with the inner wall on the side of the first open end 13 of the first barrel body 11, so that it is convenient to drive the piston body 41 to move downward by pulling down the piston rod 42, thereby facilitating the suction of the urine sample from the first upper chamber 11-1 into the first lower chamber 11-2, so as to intercept the urine residue through the upper part of the filter 30; the piston body 41 cooperates with the inner wall on the side of the first open end 13 of the second barrel body 12, so that it is convenient to drive the piston body 41 to move upward by pushing up the piston rod 42, thereby facilitating the pressing of the diluent from the second lower chamber 12-2 into the second upper chamber 12-1, so as to dilute the urine residue and obtain a sample for methylation detection.

[0095] In one embodiment, Figure 1 , Figure 3 As shown, the urine filtering device further includes: a connecting member 18, wherein the connecting member 18 connects the first barrel body 11 and the second barrel body 12; in this embodiment, the connecting member 18 is a plurality of connecting columns.

[0096] The first barrel body 11 and the second barrel body 12 can be connected by the connecting piece 18. In particular, when the connection strength of the connecting piece 18 is so small that the user can break it by hand to separate the first barrel body 11 and the second barrel body 12, the connecting piece 18 can be torn off during the above-mentioned "replacement step" to separate the first barrel body 11 and the second barrel body 12, and the first barrel body 11 sealed with the treated urine can be directly thrown away.

[0097] In one embodiment, Figure 1 , Figure 3 As shown, the urine filtering device further includes: a handle 17 , and the handle 17 is disposed on the first barrel body 11 and / or the second barrel body 12 .

[0098] The handle 17 is provided to facilitate the use of the device by a person. In particular, when the handle 17 is provided along the length direction of the first barrel body 11 and the second barrel body 12 and distributed on both sides of the upper and lower sides of the chute, if it is provided as a reinforcing rib structure, the connection strength of the upper and lower chambers can be increased, making it less likely to deform, and reducing the impact of the reduced structural strength caused by the provision of the chute.

[0099] Although the embodiments of the present application are described above, the present application is not limited to the above specific embodiments and application fields, and the above specific embodiments are merely illustrative and instructive, rather than restrictive. A person of ordinary skill in the art can make many forms under the guidance of this specification and without departing from the scope of protection of the claims of the present application, all of which belong to the scope of protection claimed in the present application.

Claims

1. A urine filtering device, comprising: A first barrel body and a second barrel body, wherein one end of the first barrel body and the second barrel body is set as a first open end, and the other end can be communicated with the atmosphere; and the first barrel body and the second barrel body are provided with a slide groove; A baffle and a filter screen, wherein the baffle and the filter screen can extend from the outside of the first barrel body and the second barrel body through the side walls thereof along the chute into the first barrel body or the second barrel body, and respectively divide the first barrel body or the second barrel body into two independent chambers; Two pistons are respectively matched with the inner wall of one side of the first opening end of the first barrel body and the second barrel body.

2. The urine filtration device according to claim 1, wherein: The other end of the first barrel body and / or the second barrel body is configured as a second open end; The urine filtering device also includes: A cover body, wherein the cover body is matched with the second open end of the first barrel body and / or the second barrel body; and an air hole is arranged on the cover body.

3. The urine filtration device according to claim 1, wherein: The equivalent circular diameter of the pores is less than 4 mm.

4. The urine filtration device according to claim 1, wherein: The baffle comprises: Baffle body; a first sealing ring, which is disposed on the baffle body and is used to seal the baffle body and the inner wall of the first barrel body or the second barrel body when the baffle is inserted into the slide groove; The first pulling portion is arranged on the baffle body and is used for pulling the baffle body.

5. The urine filtration device according to claim 1, wherein: The filter comprises: Frame; A filter body, wherein the filter body is laid on the frame; a second sealing ring, which is disposed on the frame body and is used to seal the frame body and the inner wall of the first barrel body or the second barrel body when the filter screen is inserted into the chute; A second pull-out portion, disposed on the frame body, for pulling out the frame body; Preferably, the pore size of the filter body is 1-200 nm.

6. The urine filtration device according to claim 5, wherein: The filter screen also includes: A support body, the support body is arranged on the frame body and located at the bottom of the filter body, so as to support the filter body; Preferably, the support body is a load-bearing net.

7. The urine filtration device according to claim 1, wherein: The piston comprises: A piston body, wherein the piston body can cooperate with the inner wall of one side of the first opening end of the first barrel body and the second barrel body; A piston rod, one end of which is connected to the piston body.

8. The urine filtration device according to claim 1, wherein: The urine filtering device also includes: A connecting piece, wherein the connecting piece connects the first barrel body 11 and the second barrel body 12.

9. The urine filtration device according to claim 1, wherein: The urine filtering device also includes: A handle is arranged on the first barrel body and / or the second barrel body.

10. A method for filtering urine, using the urine filtering device according to any one of claims 1 to 9 to filter urine, wherein: The first opening ends of the first barrel body and the second barrel body face downward; the filter screen extends into the first barrel body through the slide groove of the first barrel body to divide the first barrel body into a first upper chamber and a first lower chamber; the baffle extends into the second barrel body through the slide groove of the second barrel body to divide the second barrel body into a second upper chamber and a second lower chamber; one of the pistons extends into the first lower chamber; Another of the pistons seals the first open end of the second barrel to store the diluent in the second lower chamber; The method comprises: The sample adding and filtering step comprises: adding a urine sample into the first upper chamber, and downwardly pulling a piston inserted into the first lower chamber, so that the urine sample is sucked from the first upper chamber into the first lower chamber, and urine residues are intercepted on the upper part of the filter; The replacement step includes: exchanging the positions of the filter screen and the baffle plate, and keeping the side of the filter screen that intercepts urine residues facing upward; The dilution step pushes the piston sealing the first open end of the second barrel body to press the diluent from the second lower chamber into the second upper chamber, and the diluent flushes the urine residue on the filter screen and dilutes the urine residue.

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