Full-automatic pathological tissue slicing device

By designing a fully automatic pathological tissue slicing device, using technical means such as reciprocating motion locking mechanism and horizontal propulsion mechanism, the problems of low continuity and cross-contamination caused by manual operation of pathological tissue slicing in the prior art are solved, and an efficient and automated slicing process is achieved.

CN119526493AInactive Publication Date: 2025-02-28ZHONGSHAN HOSPITAL AFFILIATED TO FUDAN UNIV XIAMEN HOSPITAL
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Patent Information

Application Number
CN202411757345.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-03
Publication Date
2025-02-28
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

In the prior art, the pathological tissue slicing process is manually operated, resulting in low slice continuity, cumbersome debris cleaning and prone to cross-contamination.

Method used

A fully automatic pathological tissue slicing device is designed, including a reciprocating motion locking mechanism, a horizontal propulsion mechanism, a paraffin pathological tissue block fixing mechanism, a cutting knife mechanism and a debris aspiration mechanism, to realize automatic slice and debris cleaning of paraffin pathological tissue.

Benefits of technology

Efficient and automated pathological tissue sections are achieved, which improves section continuity, reduces the complexity of debris cleaning, and avoids cross-contamination.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention provides a full-automatic pathological tissue slicing device. The full-automatic pathological tissue slicing device comprises a base, a reciprocating motion locking mechanism is arranged at the top of the base, a horizontal pushing mechanism is arranged on the reciprocating motion locking mechanism, and a paraffin pathological tissue block fixing mechanism is arranged on the reciprocating motion locking mechanism. A cutter mechanism mounted at the top of the base is arranged on one side of the paraffin pathological tissue block fixing mechanism; the paraffin pathological tissue block fixing mechanism is used for fixing a paraffin pathological tissue block; the reciprocating motion locking mechanism is used for conducting longitudinal reciprocating motion on the pathological tissue and meanwhile is matched with the cutter mechanism to slice the pathological tissue. The full-automatic pathological tissue slicing device provided by the invention has the advantages that the use is efficient, time and labor are saved, the labor cost is saved, paraffin pathological tissue slicing can be autonomously and controllably carried out, and chipping cross contamination is removed in time.
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Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a fully automatic pathological tissue slicing device. Background Art

[0002] Pathological sections are made by taking a certain size of lesion tissue, using pathological histological methods to make pathological sections, and using a microscope to further examine the lesion. The occurrence and development process of the lesion, and finally make a pathological diagnosis.

[0003] Most of the pathological tissue sections used in the prior art are embedded in paraffin and then sectioned. However, in the prior art, the sectioning process is mostly done manually, which easily leads to low continuity of the sectioning. At the same time, it is cumbersome to clean the debris generated by the sectioning, which easily leads to cross contamination when the section is sliced ​​again.

[0004] Therefore, it is necessary to provide a new fully automatic pathological tissue slicing device to solve the above-mentioned technical problems. Summary of the invention

[0005] The technical problem solved by the present invention is to provide a fully automatic pathological tissue slicing device which is efficient, time-saving, labor-saving, and manpower-saving, and can autonomously and controllably perform paraffin pathological tissue slicing and timely remove debris cross contamination.

[0006] In order to solve the above technical problems, the fully automatic pathological tissue slicing device provided by the present invention comprises: a base, a reciprocating locking mechanism is provided on the top of the base, a horizontal propulsion mechanism is provided on the reciprocating locking mechanism, a paraffin pathological tissue block fixing mechanism is provided on the reciprocating locking mechanism, a cutting mechanism installed on the top of the base is provided on one side of the paraffin pathological tissue block fixing mechanism, a debris suction mechanism is provided on the cutting mechanism, and paraffin section inspection mechanisms are provided on both sides of the cutting mechanism; The paraffin pathological tissue block fixing mechanism is used to fix the paraffin pathological tissue block; The reciprocating locking mechanism is used to perform longitudinal reciprocating motion on the pathological tissue and simultaneously cooperate with the cutting mechanism to slice the pathological tissue; The horizontal propulsion mechanism is used to move the paraffin pathological tissue block laterally toward the cutting mechanism when the reciprocating locking mechanism performs longitudinal reciprocating motion on the pathological tissue, thereby achieving continuous tissue slicing; The paraffin section inspection mechanism is used to scan and monitor the thickness of tissue sections and the flatness of wax blocks in real time; The debris suction mechanism is used to promptly remove debris tissue that may be cross-contaminated.

[0007] Preferably, the reciprocating locking mechanism includes a support plate arranged above the base, a power shaft is rotatably installed on the top of the support plate, a connecting plate is fixedly installed on one end of the power shaft, a lifting rod is fixedly installed on the side of the connecting plate away from the power shaft, the lifting rod and the power shaft are not arranged concentrically, two return strips are sleeved on the outer side of the lifting rod, a mounting block is fixedly installed on the same side of the two return strips, two lifting rails are symmetrically fixedly installed on the top of the support plate, and the two mounting blocks are slidably connected to the two lifting rails respectively.

[0008] Preferably, a motor is fixedly mounted on the top of the support plate, and an output shaft of the motor is connected to the power shaft via a first belt.

[0009] Preferably, two rotating seats are fixedly mounted on the top of the support plate, the power shaft is rotatably mounted on the two rotating seats, and the power shaft passes through the rotating seats.

[0010] Preferably, the horizontal propulsion mechanism includes a first rotating rod rotatably installed between the two rotating shafts, the first rotating rod is connected to the power shaft by a second belt, the first rotating rod is fixedly sleeved with a first bevel gear, the support plate is rotatably installed with a second rotating rod, the second rotating rod passes through the support plate, the top fixed sleeve of the second rotating rod is provided with a second bevel gear, the second bevel gear is meshed with the first bevel gear, the bottom fixed sleeve of the second rotating rod is provided with a third bevel gear, the bottom of the support plate is rotatably installed with a third rotating rod, the outer fixed sleeve of the third rotating rod is provided with a fourth bevel gear, the fourth bevel gear is meshed with the third bevel gear, the top of the base is rotatably installed with two translation screws, the outer threaded sleeve of the translation screw is provided with an internal threaded sleeve, the internal threaded sleeve is rotatably installed at the bottom of the support plate, and the third rotating rod is connected to the two internal threaded sleeves by two third belts.

[0011] Preferably, a slider is fixedly mounted on the bottom end of the support plate, a slide rail is fixedly mounted on the top of the base, and the slider is slidably mounted on the slide rail.

[0012] Preferably, the paraffin pathological tissue block fixing mechanism includes a positioning frame with an opening on one side fixedly mounted on one of the mounting blocks, one end of a plurality of first springs is fixedly mounted on an inner wall of one side of the positioning frame, the other ends of the plurality of first springs are fixedly mounted on the same baffle, the baffle is slidably mounted in the positioning frame, an outer box with an opening on one side is fixedly mounted on the inner wall of the positioning frame, a limit stop box is slidably mounted in the outer box, one end of a plurality of second springs is fixedly mounted in the limit stop box, the other end of the second spring is connected to the outer box, a mounting plate is fixedly mounted on the outer box, an elastic plate is fixedly mounted on the mounting plate, a limit column is fixedly mounted on the elastic plate, a limit groove is provided on the limit stop box, and an end of the limit column away from the elastic plate is located in the limit groove.

[0013] Preferably, sliding holes are provided on the inner walls on both sides of the outer box, and limiting blocks are fixedly installed on both sides of the positioning stop box, and the limiting blocks pass through the corresponding sliding holes.

[0014] Preferably, the cutter mechanism comprises a cutter fixedly mounted on the top of the base, and the cutter is wedge-shaped.

[0015] Preferably, the cutter mechanism includes a cutter slidably mounted on the top of the base, a sliding block is fixedly mounted on the bottom of the cutter, a sliding seat is fixedly mounted on the top of the base, the sliding block is slidably mounted on the sliding seat, fixed blocks are fixedly mounted on both sides of the cutter, a lifting screw is threadedly mounted on the fixed block, a first wedge block is rotatably mounted on the bottom end of the lifting screw, two second wedge blocks are fixedly mounted on the top of the base, and the inclined surface of the first wedge block contacts the inclined surface of the second wedge block.

[0016] Compared with the related art, the fully automatic pathological tissue slicing device provided by the present invention has the following beneficial effects: The present invention provides a fully automatic pathological tissue slicing device. Through a paraffin pathological tissue block fixing mechanism composed of a positioning frame, a first spring, a baffle, a limit stop box, an outer box, a mounting plate, an elastic plate, a limit column, a limit groove, a limit block and a second spring, the device can quickly and conveniently install paraffin-embedded pathological tissue of a specific size, and can quickly and conveniently remove the unsliced ​​paraffin-embedded pathological tissue from the positioning frame after the slicing is completed; through a reciprocating motion locking mechanism composed of a support plate, a power shaft, a connecting plate, a lifting rod, a return strip, a mounting block, a lifting rail, a rotating seat, a motor and a first belt, the paraffin-embedded pathological tissue can be made to perform longitudinal reciprocating motion, and in coordination with a first rotating rod, a second belt, a first bevel gear, a second bevel gear, a second rotating rod, a third bevel gear, a third rotating rod, a fourth bevel gear, a mounting seat, a translation screw, an internal threaded sleeve, a third belt, a slide rail The horizontal propulsion mechanism formed by the slider can make the paraffin-embedded pathological tissue approach the cutter while making longitudinal reciprocating motion, so that the automatic slicing of the paraffin-embedded pathological tissue can be realized in cooperation with the cutter; the elastic rubber plate and the protective cover cooperate to prevent the debris generated when slicing the paraffin-embedded pathological tissue from falling into the reciprocating motion locking mechanism and the horizontal propulsion mechanism, and can ensure the normal movement of the reciprocating motion locking mechanism and the horizontal propulsion mechanism, and also avoid the cleaning of the reciprocating motion locking mechanism and the horizontal propulsion mechanism; the cutter mechanism composed of the cutter, the fixed block, the lifting screw, the first wedge block, the second wedge block, the sliding seat and the sliding block can cooperate with the reciprocating motion locking mechanism and the horizontal propulsion mechanism to realize the automatic slicing of the paraffin-embedded pathological tissue, and can facilitate the cleaning of the debris after the slicing is completed, so as to avoid the cross contamination of the paraffin-embedded pathological tissue when slicing. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 A schematic structural diagram of a preferred embodiment of the fully automatic pathological tissue slicing device provided by the present invention; Figure 2 for Figure 1 The schematic diagram of the structure after the paraffin section inspection mechanism and the debris suction mechanism are removed is shown; Figure 3 for Figure 2 The schematic diagram of the structure after the protective cover is removed is shown; Figure 4 for Figure 3 A schematic diagram of the structure from another perspective is shown; Figure 5 for Figure 3 A schematic diagram of the connection structure of the reciprocating locking mechanism, the horizontal propulsion mechanism and the paraffin pathological tissue block fixing mechanism shown; Figure 6 for Figure 5The structural schematic diagram of the reciprocating locking mechanism shown; Figure 7 for Figure 5 A schematic diagram of the connection structure between the horizontal propulsion mechanism and the partial reciprocating motion locking mechanism shown; Figure 8 for Figure 7 The schematic diagram of the structure after the support plate is removed is shown; Fig. 9 for Figure 5 The exploded structural diagram of the paraffin pathological tissue block fixing mechanism shown; Fig.10 for Fig. 9 The schematic diagram of the structure after removing the mounting block, the positioning frame, the first spring and the baffle is shown; Fig.11 for Fig.10 The front view structural schematic diagram shown; Fig.12 for Fig.11 Schematic diagram of the explosion structure shown; Fig.13 for Figure 2 The structural schematic diagram of the cutter mechanism shown; Fig.14 for Fig.13 A schematic diagram of the exploded structure from another perspective is shown.

[0018] Numbers in the figure: 1, base, 2, reciprocating motion locking mechanism, 201, support plate, 202, power shaft, 203, connecting plate, 204, lifting rod, 205, return strip, 206, mounting block, 207, lifting rail, 208, rotating seat, 209, motor, 210, first belt, 3, horizontal propulsion mechanism, 301, first rotating rod, 302, second belt, 303, first bevel gear, 304, second bevel gear, 305, second rotating rod, 306, third bevel gear, 307, third rotating rod, 308, fourth bevel gear, 309, mounting seat, 310, translation screw, 311 , internal threaded sleeve, 312, third belt, 313, slide rail, 314, slider, 4, paraffin pathological tissue block fixing mechanism, 401, positioning frame, 402, first spring, 403, baffle, 404, limit block box, 405, outer box, 406, mounting plate, 407, elastic plate, 408, limit column, 409, limit groove, 410, limit block, 411, second spring, 5, elastic rubber plate, 6, cutter mechanism, 601, cutter, 602, fixed block, 603, lifting screw, 604, first wedge block, 605, second wedge block, 606, sliding seat, 607, sliding block, 7, protective cover. DETAILED DESCRIPTION

[0019] The present invention will be further described below in conjunction with the accompanying drawings and implementation modes.

[0020] Please refer to Figure 1-Figure 14 ,in, Figure 1 A schematic structural diagram of a preferred embodiment of the fully automatic pathological tissue slicing device provided by the present invention; Figure 2 for Figure 1 The schematic diagram of the structure after the paraffin section inspection mechanism and the debris suction mechanism are removed is shown; Figure 3 for Figure 2 The schematic diagram of the structure after the protective cover is removed is shown; Figure 4 for Figure 3 A schematic diagram of the structure from another perspective is shown; Figure 5 for Figure 3 A schematic diagram of the connection structure of the reciprocating locking mechanism, the horizontal propulsion mechanism and the paraffin pathological tissue block fixing mechanism shown; Figure 6 for Figure 5 The structural schematic diagram of the reciprocating locking mechanism shown; Figure 7 for Figure 5 A schematic diagram of the connection structure between the horizontal propulsion mechanism and the partial reciprocating motion locking mechanism shown; Figure 8 for Figure 7 The schematic diagram of the structure after the support plate is removed is shown; Fig. 9 for Figure 5 The exploded structural diagram of the paraffin pathological tissue block fixing mechanism shown; Fig.10 for Fig. 9 The schematic diagram of the structure after removing the mounting block, the positioning frame, the first spring and the baffle is shown; Fig.11 for Fig.10 The front view structural schematic diagram shown; Fig.12 for Fig.11 Schematic diagram of the explosion structure shown; Fig.13 for Figure 2 The structural schematic diagram of the cutter mechanism shown; Fig.14 for Fig.13 The exploded structure schematic diagram of another perspective is shown. The fully automatic pathological tissue slicing device comprises: a base 1, a reciprocating locking mechanism 2 is provided on the top of the base 1, a horizontal propulsion mechanism 3 is provided on the reciprocating locking mechanism 2, a paraffin pathological tissue block fixing mechanism 4 is provided on the reciprocating locking mechanism 2, a cutting mechanism 6 installed on the top of the base 1 is provided on one side of the paraffin pathological tissue block fixing mechanism 4, a debris suction mechanism 9 is provided on the cutting mechanism 6, and paraffin section inspection mechanisms 8 are provided on both sides of the cutting mechanism 6; The paraffin pathological tissue block fixing mechanism 4 is used to fix the paraffin pathological tissue block; The reciprocating locking mechanism 2 is used to perform longitudinal reciprocating motion on the pathological tissue, and simultaneously cooperates with the cutting mechanism to slice the pathological tissue; The horizontal propulsion mechanism 3 is used to move the paraffin pathological tissue block laterally toward the cutting mechanism 6 when the reciprocating locking mechanism 2 performs longitudinal reciprocating motion on the pathological tissue, thereby achieving continuous tissue sectioning; The paraffin section inspection mechanism 8 is used to scan and monitor the thickness of tissue sections and the flatness of wax blocks in real time; The debris suction mechanism 9 is used to promptly remove possible cross-contaminated debris tissue.

[0021] The reciprocating locking mechanism 2 includes a support plate 201 arranged above the base 1, and a power shaft 202 is rotatably installed on the top of the support plate 201, and a connecting plate 203 is fixedly installed on one end of the power shaft 202, and a lifting rod 204 is fixedly installed on the side of the connecting plate 203 away from the power shaft 202, and the lifting rod 204 and the power shaft 202 are not arranged concentrically, and two return strips 205 are sleeved on the outer side of the lifting rod 204, and a mounting block 206 is fixedly installed on the same side of the two return strips 205, and two lifting rails 208 are symmetrically fixedly installed on the top of the support plate 201, and the two mounting blocks 206 are slidably connected to the two lifting rails 207 respectively.

[0022] A motor 209 is fixedly mounted on the top of the support plate 201 , and an output shaft of the motor 209 is connected to the power shaft 202 via a first belt 210 .

[0023] Two rotating seats 208 are fixedly installed on the top of the support plate 201 , and the power shaft 202 is rotatably installed on the two rotating seats 208 . The power shaft 202 passes through the rotating seats 208 .

[0024] The horizontal propulsion mechanism 3 includes a first rotating rod 301 rotatably mounted between the two rotating shafts 208, the first rotating rod 301 is connected to the power shaft 202 through a second belt 302, a first bevel gear 303 is fixedly sleeved on the first rotating rod 301, a second rotating rod 305 is rotatably mounted on the support plate 201, the second rotating rod 305 penetrates the support plate 201, a second bevel gear 304 is fixedly sleeved on the top end of the second rotating rod 305, the second bevel gear 304 is meshed with the first bevel gear 303, a third bevel gear 306 is fixedly sleeved on the bottom end of the second rotating rod 305, and the bottom of the support plate 201 is fixedly sleeved with a third bevel gear 306. A third rotating rod 307 is rotatably installed, and a fourth bevel gear 308 is fixedly sleeved on the outer side of the third rotating rod 307, and the fourth bevel gear 308 is meshed with the third bevel gear 306. Two translation screws 310 are rotatably installed on the top of the base 1, and four mounting seats 309 are fixedly installed on the top of the base 1. The translation screw 310 is rotatably installed on two corresponding mounting seats 309, and an inner threaded sleeve 311 is rotatably installed on the outer threaded sleeve of the translation screw 310. The inner threaded sleeve 311 is rotatably installed on the bottom of the support plate 201, and the third rotating rod 307 is connected to the two inner threaded sleeves 311 through two third belts 312.

[0025] A slider 314 is fixedly mounted on the bottom end of the support plate 201 , a slide rail 313 is fixedly mounted on the top of the base 1 , and the slider 314 is slidably mounted on the slide rail 313 .

[0026] The paraffin pathological tissue block fixing mechanism 4 includes a positioning frame 401 with an opening on one side fixedly mounted on one of the mounting blocks 206, one end of a plurality of first springs 402 is fixedly mounted on an inner wall of one side of the positioning frame 401, and the other end of the plurality of first springs 402 is fixedly mounted with a same baffle 403, the baffle 403 is slidably mounted in the positioning frame 401, an outer box 405 with an opening on one side is fixedly mounted on the inner wall of the positioning frame 401, a limit stop box 404 is slidably mounted in the outer box 405, and the limit stop box 404 and the baffle 403 are slidably mounted. Fixedly connected, the outer box 405 is fixedly connected to the inner wall of the positioning frame 401, one end of a plurality of second springs 411 is fixedly installed in the limit stop box 404, the other end of the second spring 411 is connected to the outer box 405, a mounting plate 406 is fixedly installed on the outer box 405, an elastic plate 407 is fixedly installed on the mounting plate 406, a limiting column 408 is fixedly installed on the elastic plate 407, a limiting groove 409 is provided on the limit stop box 404, and one end of the limiting column 408 away from the elastic plate 407 is located in the limiting groove 409.

[0027] Sliding holes are provided on the inner walls of both sides of the outer box 405 , and limiting blocks 410 are fixedly installed on both sides of the positioning stop box 404 , and the limiting blocks 410 pass through the corresponding sliding holes.

[0028] In this embodiment, the cutter mechanism 6 includes a cutter 601 slidably mounted on the top of the base 1, a sliding block 607 is fixedly mounted on the bottom of the cutter 601, a sliding seat 606 is fixedly mounted on the top of the base 1, and the sliding block 607 is slidably mounted on the sliding seat 606. Fixed blocks 602 are fixedly mounted on both sides of the cutter 601, and a lifting screw 603 is threadedly mounted on the fixed block 602. A first wedge block 604 is rotatably mounted on the bottom end of the lifting screw 603. Two second wedge blocks 605 are fixedly mounted on the top of the base 1, and the inclined surface of the first wedge block 604 is in contact with the inclined surface of the second wedge block 605.

[0029] A protective cover 7 is fixedly mounted on the top of the base 1 , and the cutter 601 is in contact with the protective cover 7 . A through hole is opened on one side of the protective cover 7 , and an elastic rubber plate 5 is arranged in the through hole. The elastic rubber plate 5 is fixedly connected to one of the mounting blocks 206 .

[0030] like Figure 1 As shown, the two paraffin section inspection mechanisms 8 are respectively fixedly mounted on both sides of the protective cover 7, and the paraffin section inspection mechanisms 8 are infrared or laser probes.

[0031] The debris suction mechanism 9 is installed on the side of the cutter 601 away from the protective cover 7. The debris suction mechanism 9 includes a suction head. A connecting head is provided on the side of the suction head away from the cutter 601. The connecting head is externally connected to a negative pressure tube, and the paraffin pathological tissue section debris on the cutter 601 is cleaned by using negative pressure.

[0032] In other embodiments, the cutter mechanism 6 may only include a cutter 601 fixedly mounted on the top of the base 1, and the cutter 601 is wedge-shaped.

[0033] The working principle of the fully automatic pathological tissue slicing device provided by the present invention is as follows: When in use, firstly, the paraffin-embedded pathological tissue is placed in the positioning frame 401. When the paraffin-embedded pathological tissue contacts the baffle 403, the paraffin-embedded pathological tissue pushes the baffle 403 to move, and the baffle 403 pushes the limit stop box 404 to move in the outer box 405. The first spring 402 and the second spring 411 are compressed. At this time, the limit post 408 moves in the limit groove 409, and the elastic plate 407 is twisted. When the limit post 408 contacts the inner wall of the limit groove 409 on one side away from the outer box 405, the paraffin-embedded pathological tissue cannot move. At this time, you only need to let go. Under the elastic force of the first spring 402 and the second spring 411, the limit post 408 is stuck in the slot on the limit groove 409. At this time, the installation of the paraffin-embedded pathological tissue is completed. After installation, less than half of the volume of the paraffin-embedded pathological tissue is located outside the positioning frame 401, which is convenient for slicing. The motor 209 is started, and the motor 209 drives the power shaft 202 to rotate through the first belt 210, and the power shaft 202 drives the connecting plate 203 to rotate, and the connecting plate 203 drives the lifting rod 204 to rotate with the power shaft 202 as the axis. When the lifting rod 204 rotates from bottom to top, the lifting rod 204 slides in the return bar 205 and drives the return bar 205 to move upward. The return bar 205 drives the two mounting blocks 206 to slide upward on the lifting rail 207, and the mounting blocks 206 drive the positioning frame 401 to move upward, thereby driving the paraffin-embedded pathological tissue to move upward. When the lifting rod 204 rotates from top to bottom, the paraffin-embedded pathological tissue moves downward, thereby realizing the up and down movement of the paraffin-embedded pathological tissue; While the motor 209 is rotating, the power shaft 202 drives the first rotating rod 301 to rotate through the second belt 302, the first rotating rod 301 drives the second rotating rod 305 to rotate through the first bevel gear 303 and the second bevel gear 304, the second rotating rod 305 drives the third rotating rod 307 to rotate through the third bevel gear 306 and the fourth bevel gear 308, and the third rotating rod 307 drives the internal threaded sleeve 311 to rotate on the outside of the translation screw 310 through the third belt 312, so that the internal threaded sleeve 311 rotates on the translation screw 310 while driving the support plate 201 to move toward the direction close to the cutter 601, so that the paraffin-embedded pathological tissue moves toward the direction close to the cutter 601, thereby realizing the automatic sectioning of the paraffin-embedded pathological tissue.

[0034] When the slicing is completed and the unsliced ​​paraffin-embedded pathological tissue needs to be removed, it is only necessary to continue pressing the paraffin-embedded pathological tissue to make the baffle plate 403 continue to move into the positioning frame 401. At this time, the limiting column 408 contacts the inner wall of the limiting groove 409 away from the outer box 405 again. At this time, the elastic force of the elastic plate 407 makes the elastic plate 407 parallel to the mounting plate 406. At this time, it is only necessary to loosen the paraffin-embedded pathological tissue, and the unsliced ​​paraffin-embedded pathological tissue can be ejected from the positioning frame 401 under the elastic force of the first spring 402 and the second spring 411. When it is necessary to clean the cutter 601, the positioning frame 401 and the baffle 403, it is only necessary to rotate the lifting screw 603. The lifting screw 603 rotates on the fixed block 602 and drives the first wedge block 604 to move upward until the first wedge block 604 moves to above the second wedge block 605. At this time, it is only necessary to pull the lifting screw 603 to disengage the cutter 601 from the protective cover 7, so that the cutter 601, the positioning frame 401 and the baffle 403 can be cleaned conveniently, and the protective cover and the elastic rubber plate 5 can also be cleaned conveniently, so as to ensure that the next slice will not be cross-contaminated.

[0035] Compared with the related art, the fully automatic pathological tissue slicing device provided by the present invention has the following beneficial effects: The present invention provides a fully automatic pathological tissue slicing device, which can quickly and conveniently install paraffin-embedded pathological tissue of a specific size through a paraffin pathological tissue block fixing mechanism 4 composed of a positioning frame 401, a first spring 402, a baffle 403, a limit stop box 404, an outer box 405, a mounting plate 406, an elastic plate 407, a limit column 408, a limit groove 409, a limit block 410 and a second spring 411, and can quickly and conveniently remove the paraffin-embedded pathological tissue that has not been sliced ​​from the positioning frame 401 after slicing is completed; The reciprocating motion locking mechanism 2 composed of the support plate 201, the power shaft 202, the connecting plate 203, the lifting rod 204, the return strip 205, the mounting block 206, the lifting rail 207, the rotating seat 208, the motor 209 and the first belt 210 can realize the longitudinal reciprocating motion of the paraffin-embedded pathological tissue, and the first rotating rod 301, the second belt 302, the first bevel gear 303, the second bevel gear 304, the second rotating rod 305, the third bevel gear 306, the third rotating rod 307, the fourth bevel gear 308, the mounting seat 310 and the second belt 311 can realize the longitudinal reciprocating motion of the paraffin-embedded pathological tissue. 09. The horizontal propulsion mechanism 3 composed of the translation screw 310, the internal threaded sleeve 311, the third belt 312, the slide rail 313 and the slider 314 can make the paraffin-embedded pathological tissue approach the cutter 601 while making longitudinal reciprocating motion, so as to cooperate with the cutter 601 to realize the automatic slicing of the paraffin-embedded pathological tissue; the elastic rubber plate 5 and the protective cover 7 cooperate to prevent the debris generated when slicing the paraffin-embedded pathological tissue from falling into the reciprocating motion locking mechanism 2 and the horizontal propulsion mechanism 3, and can ensure that the reciprocating motion locking mechanism 2 and the horizontal propulsion mechanism The normal movement of the propulsion mechanism 3 also avoids the cleaning of the reciprocating locking mechanism 2 and the horizontal propulsion mechanism 3; the cutter mechanism 6 composed of the cutter 601, the fixed block 602, the lifting screw 603, the first wedge block 604, the second wedge block 605, the sliding seat 606 and the sliding block 607 can cooperate with the reciprocating locking mechanism 2 and the horizontal propulsion mechanism 3 to realize automatic slicing of paraffin-embedded pathological tissue, and at the same time can facilitate the cleaning of debris after slicing, thereby avoiding cross contamination of paraffin-embedded pathological tissue during slicing.

[0036] The above descriptions are merely embodiments of the present invention and are not intended to limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made using the contents of the present invention specification and drawings, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. A fully automatic pathological tissue sectioning device, characterized in that: include: A base, wherein a reciprocating locking mechanism is provided on the top of the base, a horizontal propulsion mechanism is provided on the reciprocating locking mechanism, a paraffin pathological tissue block fixing mechanism is provided on the reciprocating locking mechanism, a cutting mechanism installed on the top of the base is provided on one side of the paraffin pathological tissue block fixing mechanism, a debris suction mechanism is provided on the cutting mechanism, and paraffin section inspection mechanisms are provided on both sides of the cutting mechanism; The paraffin pathological tissue block fixing mechanism is used to fix the paraffin pathological tissue block; The reciprocating locking mechanism is used to perform longitudinal reciprocating motion on the pathological tissue and simultaneously cooperate with the cutting mechanism to slice the pathological tissue; The horizontal propulsion mechanism is used to move the paraffin pathological tissue block laterally toward the cutting mechanism when the reciprocating locking mechanism performs longitudinal reciprocating motion on the pathological tissue, thereby achieving continuous tissue slicing; The paraffin section inspection mechanism is used to scan and monitor the thickness of tissue sections and the flatness of wax blocks in real time; The debris suction mechanism is used to promptly remove debris tissue that may be cross-contaminated.

2. The fully automatic pathological tissue slicing device according to claim 1, characterized in that: The reciprocating locking mechanism includes a support plate arranged above the base, a power shaft is rotatably installed on the top of the support plate, a connecting plate is fixedly installed on one end of the power shaft, a lifting rod is fixedly installed on the side of the connecting plate away from the power shaft, the lifting rod and the power shaft are not arranged concentrically, two return strips are sleeved on the outer side of the lifting rod, and a mounting block is fixedly installed on the same side of the two return strips, and two lifting rails are symmetrically fixedly installed on the top of the support plate, and the two mounting blocks are slidably connected to the two lifting rails respectively.

3. The fully automatic pathological tissue slicing device according to claim 2, characterized in that: A motor is fixedly mounted on the top of the support plate, and an output shaft of the motor is connected to the power shaft via a first belt.

4. The fully automatic pathological tissue slicing device according to claim 2, characterized in that: Two rotating seats are fixedly installed on the top of the support plate, and the power shaft is rotatably installed on the two rotating seats, and the power shaft passes through the rotating seats.

5. The fully automatic pathological tissue slicing device according to claim 4, characterized in that: The gear mechanism is a plurality of gears, and the plurality of gears are connected to each other with a plurality of gears, and the plurality of gears are connected with each other with a plurality of gears, and the plurality of gears are connected with each other with a plurality of gears.

6. The fully automatic pathological tissue slicing device according to claim 5, characterized in that: A sliding block is fixedly installed at the bottom end of the support plate, a sliding rail is fixedly installed at the top of the base, and the sliding block is slidably installed on the sliding rail.

7. The fully automatic pathological tissue slicing device according to claim 2, characterized in that: The paraffin pathological tissue block fixing mechanism includes a positioning frame with an opening on one side fixedly mounted on one of the mounting blocks, one end of a plurality of first springs being fixedly mounted on an inner wall of one side of the positioning frame, the other ends of the plurality of first springs being fixedly mounted on the same baffle, the baffle being slidably mounted in the positioning frame, an outer box with an opening on one side being fixedly mounted on the inner wall of the positioning frame, a limit stop box being slidably mounted in the outer box, one end of a plurality of second springs being fixedly mounted in the limit stop box, the other end of the second spring being connected to the outer box, a mounting plate being fixedly mounted on the outer box, an elastic plate being fixedly mounted on the mounting plate, a limit column being fixedly mounted on the elastic plate, a limit groove being provided on the limit stop box, and an end of the limit column away from the elastic plate being located in the limit groove.

8. The fully automatic pathological tissue slicing device according to claim 2, characterized in that: Sliding holes are provided on the inner walls of both sides of the outer box, and limiting blocks are fixedly installed on both sides of the positioning stop box, and the limiting blocks pass through the corresponding sliding holes.

9. The fully automatic pathological tissue slicing device according to claim 1, characterized in that: The cutter mechanism comprises a cutter fixedly mounted on the top of the base, and the cutter is wedge-shaped.

10. The fully automatic pathological tissue slicing device according to claim 1, characterized in that: The cutter mechanism includes a cutter slidably mounted on the top of the base, a sliding block is fixedly mounted on the bottom of the cutter, a sliding seat is fixedly mounted on the top of the base, the sliding block is slidably mounted on the sliding seat, fixed blocks are fixedly mounted on both sides of the cutter, a lifting screw is threadedly mounted on the fixed block, a first wedge block is rotatably mounted on the bottom end of the lifting screw, and two second wedge blocks are fixedly mounted on the top of the base, and the inclined surface of the first wedge block contacts the inclined surface of the second wedge block.

Citation Information

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