Device implanted into corneal endothelium

Abstract

The invention relates to a device for implanting corneal endothelium. The device comprises an injector, an implanting box and a spine section, an endothelial implant is placed in the implantation box; the spine section is fixedly connected to one side of the implantation box and enables the implantation box to enter an eye anterior chamber to-be-implanted area through puncture; the injector is located on one side of the exterior of the implantation box, and the injector is communicated with the interior of the implantation box so as to inject gas into the implantation box; and the implantation box is provided with an anti-curl structure which is used for flattening the endothelial implant and implanting the endothelial implant into the to-be-implanted area of the anterior chamber of the eye after the injector injects gas. The endothelial implant flattening device has the advantages that the endothelial implant does not need to be flattened through an instrument after being implanted, and harm to a patient caused by the flattening operation of the endothelial implant is avoided.

Description

Technical Field

[0001] The invention relates to the field of medical devices, and in particular to a device for implanting corneal endothelium. Background Art

[0002] Corneal endothelial transplantation is a surgical method used to treat severe corneal endothelial diseases, such as corneal endothelial decompensation. This surgical method improves the patient's vision by transplanting healthy corneal endothelial grafts to cover the diseased endothelial surface.

[0003] After the Descemet's layer and endothelial layer of the corneal endothelial graft are completely separated from the corneal stroma, it will curl up due to the effect of surface tension. Currently, the graft is implanted in the anterior chamber of the eye in a curled shape, and then the curled graft is flattened using an instrument. Using an instrument to flatten the curled endothelial graft has the following defects:

[0004] 1. The endothelial cells of the graft are easily damaged in the process of flattening the graft using instruments;

[0005] 2. The operation time is long, causing surgical damage to the eye, aggravating the inflammatory response, and increasing the potential risk of infection;

[0006] 3. The graft is thin and small and has a front and back requirement when implanted in the anterior chamber of the eye. Flattening a curled graft may cause the graft to flip over, resulting in the front and back of the graft being reversed and causing the operation to fail. Summary of the invention

[0007] In summary, in order to overcome the deficiencies of the prior art, the technical problem to be solved by the present invention is to provide a device for implanting the corneal endothelium.

[0008] The technical solution of the present invention to solve the above technical problems is as follows: a device for implanting corneal endothelium, comprising a syringe, an implantation box and a spike segment; an endothelial graft is placed in the implantation box; the spike segment is fixedly connected to one side of the implantation box and allows the implantation box to enter the implantation area of ​​the anterior chamber of the eye through puncture; the syringe is located on the outer side of the implantation box, and the syringe is connected to the inside of the implantation box to inject gas into the implantation box; the implantation box is provided with an anti-curling structure that flattens the endothelial graft and implants it into the implantation area of ​​the anterior chamber of the eye after the syringe injects gas.

[0009] The beneficial effect of the present invention is that the endothelial graft does not need to be flattened by an instrument after implantation, thereby avoiding the harm to the patient caused by the flattening operation of the endothelial graft.

[0010] Based on the above technical solution, the present invention can also be improved as follows.

[0011] Furthermore, the anti-curling structure includes a partition and an implantation hole; the partition is fixed inside the implantation box and divides the inside of the implantation box into an upper and lower cavity, and an air hole is provided on the partition; the implantation hole matches the shape and size of the endothelial graft and is located at the top of the implantation box; the syringe is connected to the lower cavity, and the endothelial graft is placed in the upper cavity and located on the partition.

[0012] The beneficial effect of adopting the above further solution is: the endothelial graft is flattened and implanted into the waiting area of ​​the anterior chamber of the eye by gas.

[0013] Furthermore, a cover plate is provided on the side of the implantation box at a position corresponding to the upper cavity, which can be opened or closed to open or close the upper cavity.

[0014] The beneficial effect of adopting the above further solution is that an endothelial graft is placed in the upper cavity.

[0015] Furthermore, the bottom of one side of the implant box is provided with an air inlet port connected to the lower cavity, and the syringe outlet is detachably plugged into the air inlet port.

[0016] The beneficial effect of adopting the above further solution is that it is easy for the syringe to absorb gas.

[0017] Furthermore, the syringe is filled with C3F8 gas.

[0018] The beneficial effect of adopting the above further solution is: the endothelial graft is flattened by utilizing the expandability of C3F8 gas, and the flattening effect is better. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a structural schematic diagram of the present invention;

[0020] Figure 2 It is an enlarged schematic diagram of injecting gas into the implant box;

[0021] Figure 3 An enlarged schematic diagram of the endothelial graft being flattened by gas and implanted into the anterior chamber of the eye;

[0022] Figure 4 An enlarged schematic diagram of the implant box when the baffle is opened;

[0023] Therein, the dashed arrows represent gas or open stoppers.

[0024] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0025] 1. syringe, 2. implantation box, 3. spike section, 4. endothelial graft, 5. partition, 6. implantation hole, 7. pore, 8. cover plate. DETAILED DESCRIPTION

[0026] The principles and features of the present invention are described below in conjunction with the accompanying drawings. The examples given are only used to explain the present invention and are not used to limit the scope of the present invention.

[0027] like Figure 1 As shown, a device for implanting corneal endothelium is characterized in that it includes a syringe 1, an implant box 2 and a spike segment 3. An endothelial graft 4 is placed in the implant box 2. The spike segment 3 is fixedly connected to one side of the implant box 2 and allows the implant box 2 to enter the implant area of ​​the anterior chamber of the eye through puncture. The syringe 1 is on the outside side of the implant box 2, and the syringe 1 is connected to the inside of the implant box 2 to inject gas into the implant box 2. C3F8 gas is loaded in the syringe 1. The implant box 2 is provided with an anti-curling structure that flattens the endothelial graft 4 and implants it into the implant area of ​​the anterior chamber of the eye after the syringe 1 injects gas.

[0028] like Figure 2 and 3 As shown, the anti-curling structure includes a partition 5 and an implantation hole 6. The partition 5 is fixed inside the implantation box 2 and divides the inside of the implantation box 2 into an upper and lower cavity, and an air hole 7 is provided on the partition 5. The implantation hole 6 matches the shape and size of the endothelial graft 4 and is located at the top of the implantation box 2. The syringe 1 is connected to the lower cavity, and the endothelial graft 4 is placed in the upper cavity and located on the partition 5. An air inlet end connected to the lower cavity is provided at the bottom of one side of the implantation box 2, and the outlet of the syringe 1 is detachably plugged into the air inlet end.

[0029] like Figure 4 As shown, a cover plate 8 for opening or closing the upper cavity is provided at the side of the implantation box 2 corresponding to the position of the upper cavity.

[0030] When performing corneal endothelial transplantation, first remove the syringe 1 from the air inlet end of the implant box 2, pull the piston rod to absorb a certain amount of C3F8 gas in the syringe 1, and then re-insert the syringe 1 into the air inlet end of the implant box 2. Turn the cover plate 8 to open the upper cavity of the implant box 2, and then place the endothelial graft 4 coated with a protective agent (medical sodium hyaluronate to protect the endothelial graft from damage) into the upper cavity of the implant box 2 and close the cover plate 8. The protective agent has a certain adhesive force that can flatten the endothelial graft 4 without curling. Then, use the spike section 3 to puncture the anterior chamber of the patient's eye so that the implant box 2 reaches the area to be implanted. Then, slowly push the piston rod of the syringe 1 to inject the C3F8 gas inside it into the lower cavity of the implant box 2. Since the C3F8 gas has two physical properties of expansion and retention, it expands and diffuses upward through the pores 7 in the lower cavity of the implant box 2 and lifts the endothelial graft 4 in the upper cavity. Since the middle part of the endothelial graft 4 is subject to the expansion force of the C3F8 gas, while the part close to the periphery is temporarily not subject to the expansion force (the part close to the periphery is placed on the partition 5), the middle part of the endothelial graft 4 will first bulge upward and expand, and will be first implanted into the waiting area of ​​the anterior chamber of the eye through the implantation hole 6. As the gas continues to expand, the part close to the periphery of the endothelial graft 4 will then be implanted into the waiting area of ​​the anterior chamber of the eye through the implantation hole 6. At this point, the endothelial graft 4 is implanted into the waiting area in a flattened state. After the endothelial graft 4 is implanted, it does not need to be flattened by an instrument, thereby avoiding the harm caused to the patient by the flattening operation of the endothelial graft 4.

[0031] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A device for implanting corneal endothelium, characterized in that: The invention comprises a syringe (1), an implant box (2) and a spike section (3); an endothelial graft (4) is placed in the implant box (2); the spike section (3) is fixedly connected to one side of the implant box (2) and allows the implant box (2) to enter the implantation area of ​​the anterior chamber of the eye through puncture; the syringe (1) is located on the outside of the implant box (2), and the syringe (1) is connected to the inside of the implant box (2) to inject gas into the implant box (2); the implant box (2) is provided with an anti-curling structure for flattening the endothelial graft (4) and implanting it into the implantation area of ​​the anterior chamber of the eye after the syringe (1) injects gas.

2. The device for implanting corneal endothelium according to claim 1, characterized in that: The anti-curling structure comprises a partition (5) and an implantation hole (6); the partition (5) is fixed inside the implantation box (2) and divides the inside of the implantation box (2) into two layers of cavities, an upper layer and a lower layer, and an air hole (7) is provided on the partition (5); the implantation hole (6) matches the shape and size of the endothelial graft (4) and is located at the top of the implantation box (2); the syringe (1) is connected to the lower cavity, and the endothelial graft (4) is placed in the upper cavity and is located on the partition (5).

3. The device for implanting corneal endothelium according to claim 2, characterized in that: A cover plate (8) for opening or closing the upper cavity is provided at a position on the side of the implantation box (2) corresponding to the upper cavity.

4. The device for implanting corneal endothelium according to claim 2, characterized in that: An air inlet end communicating with the lower cavity is provided at the bottom of one side of the implant box (2), and the outlet of the syringe (1) is detachably plugged into the air inlet end.

5. The device for implanting corneal endothelium according to any one of claims 1 to 4, characterized in that: The syringe (1) is filled with C3F8 gas.

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