Portable uterine cavity cell sampler for reproductive clinical research

Abstract

The invention discloses a portable uterine cavity cell sampler for reproductive clinical research, relates to the technical field of gynecological sampling devices, and provides the following scheme that the portable uterine cavity cell sampler comprises a uterine cavity cell sampling rod piece, and a medical negative pressure mechanism is arranged in the right side area of the uterine cavity cell sampling rod piece; the medical negative pressure mechanism comprises a machine body, a negative pressure collecting bottle placed on the front side of the machine body, a connecting pipe and a negative pressure guiding pipe, wherein the connecting pipe and the negative pressure guiding pipe are connected to the upper end face of the negative pressure collecting bottle. According to the technical scheme, the uterine cavity cell sampling rod piece is matched with the medical negative pressure machine, the negative pressure machine is used for providing negative pressure suction capacity for the sampling rod piece, a uterine cavity solution is sucked by means of the multidirectional port in the tail end of the probing pipe fitting, the solution is collected into the negative pressure collecting bottle under the matching of all pipelines, and the negative pressure collecting bottle is used for collecting the uterine cavity cells. And sampling is carried out in a suction mode, so that the pain feeling of a patient is reduced, and damage to the uterine cavity can be reduced to a large extent.

Description

Technical Field

[0001] The invention relates to the technical field of gynecological samplers, and in particular to a portable uterine cavity cell sampler for reproductive clinical research. Background Art

[0002] Endometrial cancer is a common malignant tumor of the female reproductive system. Due to the improvement of living standards and the lack of effective screening methods, the incidence of endometrial cancer is increasing. Early detection of endometrial cancer and precancerous lesions will significantly improve the prognosis of patients and increase their survival rate. At present, the commonly used methods for monitoring endometrial lesions include transvaginal ultrasound, diagnostic curettage, hysteroscopic endometrial biopsy, etc.

[0003] Among them, diagnostic curettage is the most classic method. It has been used clinically since 1843 and is one of the most common gynecological surgeries in the world. It was once the preferred examination method for postmenopausal vaginal bleeding and was the standard for diagnosing endometrial cancer before hysteroscopy. This method is an invasive surgery. Due to blind curettage, the specimen satisfaction rate is 24%~27%, the sampling limitation is 4%~41%, and it is easy to miss the diagnosis. In addition, diagnostic curettage is an invasive surgery with obvious pain. There may be risks of complications such as bleeding, infection, uterine perforation, and intrauterine adhesions after the operation. Especially for patients with repeated transplantation failures or recurrent miscarriages, after the cervix is ​​dilated, scraping the endometrium with a curette will cause pain and discomfort to the patient. Summary of the invention

[0004] In view of the defect that routine uterine cavity sampling is proposed in the above-mentioned background technology, especially for patients with repeated implantation failures or recurrent miscarriages, scraping the endometrium with a scraper after cervical dilation will cause pain and discomfort to the patients, and increase the psychological burden on the patients, a technical solution of a portable uterine cavity cell sampler for reproductive clinical research is provided.

[0005] It includes a uterine cavity cell sampling rod, and a medical negative pressure mechanism is arranged in the right area of ​​the uterine cavity cell sampling rod; wherein the medical negative pressure mechanism includes an organism, a negative pressure collection bottle placed on the front side of the organism, and a connecting tube and a negative pressure guide tube connected to the upper end surface of the negative pressure collection bottle, and one end of the connecting tube away from the negative pressure collection bottle is connected to the negative pressure output end of the organism, and one end of the negative pressure guide tube away from the negative pressure collection bottle is connected to the inside of the uterine cavity cell sampling rod; Specifically, the negative pressure collection bottle is placed in the groove on the front side of the body, and the negative pressure collection bottle is supported and clamped by the collection bottle bracket, the connecting tube is connected to the negative pressure output port on the front side of the body in turn, and the other end of the negative pressure guide tube is connected to the bottom end port of the diversion elbow. Since the insertion depth of the connecting tube into the negative pressure collection bottle is shallower than the insertion depth of the bottom end of the negative pressure guide tube, the solution sucked by the negative pressure guide tube will be collected into the negative pressure collection bottle. At the same time, the hook on the side of the connecting block can be hooked on the support frame, so that the uterine cavity cell sampling rod has a storage function. In addition, since the top of the body has a lifting handle and the bottom of the body has a universal roller, the medical negative pressure mechanism can be moved together with the uterine cavity cell sampling rod by relying on the lifting handle to achieve a portable function.

[0006] The uterine cavity cell sampling rod comprises a handle, a connecting block fixed at the top of the handle, and an insertion tube fixed at the top of the connecting block; wherein a diversion elbow is fixed through the interior of the connecting block, a fixing ring is fixed at the top end of the connecting block, and 6-8 buckles arranged in a ring array are fixed on the top end surface of the fixing ring; The end of the probe tube is fixedly connected to a cylinder, and the interior of the cylinder is provided with 6-8 drainage tubes in a circular array; the top port of the diversion elbow is inserted into the bottom port of the probe tube, and the bottom port of the diversion elbow is connected to the end of the negative pressure guide tube away from the negative pressure collection bottle through a pipe joint.

[0007] Specifically, after the probe tube is inserted into the genitals and reaches the uterine cavity, the sampling port at the end of the probe tube and the outer port of the drainage tube are brought into contact with the surface of the uterine cavity. Under the action of negative pressure provided by the medical negative pressure mechanism, the solution in the uterine cavity is guided into the interior of the probe tube by the sampling port and the drainage tube, and the extracted solution is collected as a sample into the negative pressure collection bottle through the diversion bend and the negative pressure guide tube. Moreover, after the probe tube is used, the negative pressure collection bottle, the negative pressure guide tube and the diversion bend are rinsed and dried with clean water or cleaning fluid, and the bottom end port of the new probe tube is aligned with the upper end face of the fixing ring, and the bayonet and buckle on the bottom end face of the probe tube are used for plugging, so as to realize the replacement of the probe tube.

[0008] In the above-mentioned technical solution of a portable intrauterine cell sampler for reproductive clinical research, preferably: four universal rollers are installed at the four corners of the bottom surface of the body by screws, and a lifting handle is fixedly connected to the top surface of the body, and a support frame is fixedly connected to the left surface of the body.

[0009] In the above-mentioned technical solution of a portable uterine cavity cell sampler for reproductive clinical research, preferably: the front area of ​​the body is provided with a groove for placing a negative pressure collection bottle, and a collection bottle bracket clamped with the outer ring surface of the negative pressure collection bottle is fixedly connected to the front surface of the body.

[0010] In the technical solution of the above-mentioned portable intrauterine cell sampler for reproductive clinical research, preferably: a circle of criss-crossing anti-slip patterns is provided on the outer ring surface of the handle, and grooves are provided on the outer ring surface of the handle to fit the grip of human fingers.

[0011] In the above-mentioned technical solution of a portable intrauterine cell sampler for reproductive clinical research, preferably: a cavity is opened inside the connecting block for the diversion bend to pass through and be fixed, and the two ends of the diversion bend pass through the interior of the cavity respectively, wherein a hook is fixedly connected to the surface of the connecting block, and the hook is hooked on the support frame.

[0012] In the technical solution of the portable intrauterine cell sampler for reproductive clinical research, preferably: 5-7 rubber rings are fixed on the outer ring surface of the top of the diversion bend, and the outer ring surface of the rubber ring is in close contact with the inner wall of the bottom port of the probe tube.

[0013] In the above-mentioned technical solution of a portable intrauterine cell sampler for reproductive clinical research, preferably: a circular hole is provided inside the fixing ring for the top end of the diversion bend tube to pass through, and the top end face of the fixing ring is in contact with the bottom end face of the probe tube, wherein 6-8 bayonet holes are provided in a circular array on the bottom end face of the probe tube, and the bayonet holes and the buckles are coupled and snap-connected to each other.

[0014] In the technical solution of the portable uterine cavity cell sampler for reproductive clinical research, preferably: a sample flow cavity penetrating the cylinder is opened inside the probe tube, and a sampling port is provided at the top port position of the sample flow cavity.

[0015] In the above-mentioned technical solution of a portable intrauterine cell sampler for reproductive clinical research, preferably: 6-8 through holes are opened in a circular array on the outer ring surface of the cylinder for the drainage tube to pass through; wherein the port of the sampling port and the port of the drainage tube are both chamfered with arcs, and the outer port of the drainage tube is flush with the outer ring surface of the cylinder.

[0016] In the technical solution of the above-mentioned portable uterine cavity cell sampler for reproductive clinical research, preferably: the drainage tube is located at one end inside the cylinder and is connected to each other, and an opening for the sample flow cavity is set in the middle part after the drainage tubes are fused and connected to each other.

[0017] It can be seen from the above technical scheme that the present invention provides a portable uterine cavity cell sampler for reproductive clinical research. Compared with the prior art, the present invention has the following beneficial effects: In the technical solution of the present invention, a uterine cell sampling rod is coordinated with a medical negative pressure machine, and the negative pressure machine is used to provide negative pressure suction capability for the sampling rod. The uterine cavity solution is sucked with the help of a multi-directional port on the end of the probe tube, and the solution is collected into a negative pressure collection bottle with the cooperation of various pipelines. Sampling by suction not only reduces the patient's pain, but also can greatly reduce the damage to the uterine cavity. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces and describes the drawings required for use in the embodiments of the present invention or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention, and for ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0019] Figure 1 This is a schematic diagram of the overall structure of the uterine cavity cell sampler; Figure 2 It is a schematic diagram of the overall structure of a medical negative pressure device; Figure 3 Schematic diagram of the rod for sampling uterine cavity cells; Figure 4 is a schematic diagram of the probe pipe in the sampler; Figure 5 It is a schematic diagram of the handle mechanism in the sampler; Figure 6 For attachment Figure 4 Schematic diagram of the enlarged area A in FIG. Figure 7 For attachment Figure 4 Schematic diagram of the enlarged area B in FIG.

[0020] Attached Figure 1 -Attached Figure 7 The corresponding relationship of the parts is as follows: 1. Medical negative pressure mechanism; 11. Machine body; 12. Universal roller; 13. Collection bottle bracket; 14. Support frame; 15. Negative pressure guide tube; 16. Connecting tube; 17. Negative pressure collection bottle; 2. Uterine cavity cell sampling rod; 21. Handle; 22. Probe tube; 23. Connecting block; 24. Diversion elbow; 25. Rubber ring; 26. Fixing ring; 27. Buckle; 28. Chamber; 29. ​​Hook; 210. Cylinder; 211. Sampling port; 212. Drainage tube; 213. Through hole; 214. Sample flow cavity; 215. Bayonet. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described below are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0022] In order to more clearly explain and illustrate the technical solution and implementation of the present invention, several preferred specific embodiments for implementing the technical solution of the present invention are introduced below.

[0023] Embodiment: A preferred technical solution of a portable uterine cavity cell sampler for reproductive clinical research: Refer to the instruction manual Figure 1 As shown: it includes a uterine cavity cell sampling rod 2, and the right area of ​​the uterine cavity cell sampling rod 2 is provided with a medical negative pressure mechanism 1; wherein, refer to the attached manual Figure 2 As shown: the medical negative pressure mechanism 1 comprises an organism 11, a negative pressure collection bottle 17 placed on the front side of the organism 11, and a connecting tube 16 and a negative pressure guide tube 15 connected to the upper end surface of the negative pressure collection bottle 17, and one end of the connecting tube 16 away from the negative pressure collection bottle 17 is connected to the negative pressure output end of the organism 11, and one end of the negative pressure guide tube 15 away from the negative pressure collection bottle 17 is connected to the inside of the uterine cavity cell sampling rod 2; Refer to the instruction manual Figure 5 As shown: the uterine cavity cell sampling rod 2 includes a handle 21, a connecting block 23 fixed at the top of the handle 21, and an insertion tube 22 fixed at the top of the connecting block 23; wherein a diversion elbow 24 is fixed through the interior of the connecting block 23, a fixing ring 26 is fixed at the top end of the connecting block 23, and 6-8 buckles 27 arranged in a ring array are fixed on the top end surface of the fixing ring 26; Refer to the instruction manual Figure 6 As shown: the end of the probe tube 22 is fixedly connected to a cylinder 210, and the interior of the cylinder 210 is provided with 6-8 drainage tubes 212 in a circular array; the top end port of the diversion elbow 24 is inserted into the bottom end port of the probe tube 22, and the bottom end port of the diversion elbow 24 is connected to the end of the negative pressure guide tube 15 away from the negative pressure collection bottle 17 through a pipe joint.

[0024] Refer to the instruction manual Figure 2 As shown: four universal rollers 12 are installed at the four corners of the bottom surface of the body 11 by screws, and a lifting handle is fixedly connected to the top surface of the body 11, and a support frame 14 is fixedly connected to the left surface of the body 11. A groove for placing a negative pressure collection bottle 17 is provided in the front area of ​​the body 11, and a collection bottle bracket 13 clamped with the outer ring surface of the negative pressure collection bottle 17 is fixedly connected to the front surface of the body 11.

[0025] Refer to the instruction manual Figure 5 As shown: the outer surface of the handle 21 is provided with a circle of crisscross anti-skid lines, and the outer surface of the handle 21 is provided with grooves that fit the human fingers. The connection block 23 has a chamber 28 for the diversion bend 24 to pass through and fix, and the two ends of the diversion bend 24 pass through the chamber 28 respectively, wherein a hook 29 is fixedly connected to the surface of the connection block 23, and the hook 29 is hooked on the support frame 14. 5-7 circles of rubber rings 25 are fixed on the outer surface of the top of the diversion bend 24, and the outer surface of the rubber ring 25 is in close contact with the inner wall of the bottom end port of the probe 22. A circular hole is provided inside the fixing ring 26 for the top end of the diversion bend pipe 24 to pass through, and the top end face of the fixing ring 26 is in contact with the bottom end face of the probe tube 22, wherein 6-8 bayonet holes 215 are provided in a circular array on the bottom end face of the probe tube 22, and the bayonet holes 215 and the buckle 27 are coupled and snap-connected to each other.

[0026] Refer to the instruction manual Figure 6 As shown: a sample flow cavity 214 penetrating the cylinder 210 is provided inside the probe tube 22, and a sampling port 211 is provided at the top port position of the sample flow cavity 214; 6-8 through holes 213 are provided in a circular array on the outer surface of the cylinder 210 for the drainage tube 212 to pass through; wherein, the ports of the sampling port 211 and the ports of the drainage tube 212 are both chamfered with arcs, and the outer port of the drainage tube 212 is flush with the outer surface of the cylinder 210; the drainage tube 212 is located at one end inside the cylinder 210 and is interconnected, and an opening through which the sample flow cavity 214 passes is provided in the middle portion after the drainage tubes 212 are fused and connected.

[0027] According to the above-mentioned preferred technical solution, the workflow of the technical solution is described as follows: The negative pressure collection bottle 17 is placed in the groove on the front side of the body 11, and the negative pressure collection bottle 17 is supported and clamped by the collection bottle bracket 13, and the connecting tube 16 is connected to the negative pressure output port on the front side of the body 11 in turn, and the other end of the negative pressure guide tube 15 is connected to the bottom end port of the diversion elbow 24. Since the depth of the connecting tube 16 inserted into the negative pressure collection bottle 17 is shallower than the insertion depth of the bottom end of the negative pressure guide tube 15, the solution sucked by the negative pressure guide tube 15 will be collected in the negative pressure collection bottle 17. At the same time, the hook 29 on the side of the connecting block 23 can be hooked on the support frame 14, so that the uterine cavity cell sampling rod 2 has a storage function. In addition, since the top of the body 11 has a lifting handle and the bottom of the body 11 has a universal roller 12, the medical negative pressure mechanism 1 can be moved together with the uterine cavity cell sampling rod 2 by relying on the lifting handle to achieve a portable function.

[0028] When in use, under the guidance of color Doppler ultrasound, after the probe tube 22 is inserted into the genitals and reaches the uterine cavity, the sampling port 211 at the end of the probe tube 22 and the outer port of the drainage tube 212 are in contact with the surface of the uterine cavity. Under the action of the negative pressure provided by the medical negative pressure mechanism 1, the solution in the uterine cavity is guided into the inside of the probe tube 22 by the sampling port 211 and the drainage tube 212, and the extracted solution is collected as a sample into the inside of the negative pressure collection bottle 17 through the diversion bend 24 and the negative pressure guide tube 15. Moreover, after the probe tube 22 is used, the negative pressure collection bottle 17, the negative pressure guide tube 15 and the diversion bend 24 are rinsed and dried with clean water or cleaning fluid, and the bottom end port of the new probe tube 22 is aligned with the upper end face of the fixing ring 26, and the bayonet 215 on the bottom end face of the probe tube 22 is plugged into the buckle 27 to achieve the replacement of the probe tube 22.

[0029] The present invention is not limited to the above-mentioned optimal implementation mode. Anyone should be aware that any structural changes made under the inspiration of the present invention, and any technical solutions that are the same or similar to the present invention, fall within the protection scope of the present invention. Finally, it should be noted that the structures, proportions, sizes, etc. illustrated in the drawings of this specification are only used to match the contents disclosed in the specification for people familiar with this technology to understand and read, and are not used to limit the restrictive conditions that can be implemented in this application, so they have no technical substantive significance. Any structural modification, change in proportional relationship or adjustment of size, without affecting the effects that can be produced by this application and the purposes that can be achieved, should still fall within the scope that can be covered by the technical content disclosed in this application.

Claims

1. A portable uterine cavity cell sampler for reproductive clinical research, comprising a uterine cavity cell sampling rod (2), characterized in that: A medical negative pressure mechanism (1) is arranged in the right area of ​​the uterine cavity cell sampling rod (2); wherein the medical negative pressure mechanism (1) comprises an organism (11), a negative pressure collection bottle (17) placed on the front side of the organism (11), and a connecting tube (16) and a negative pressure guide tube (15) connected to the upper end surface of the negative pressure collection bottle (17), wherein the end of the connecting tube (16) away from the negative pressure collection bottle (17) is connected to the negative pressure output end of the organism (11), and the end of the negative pressure guide tube (15) away from the negative pressure collection bottle (17) is connected to the inside of the uterine cavity cell sampling rod (2); The intrauterine cell sampling rod (2) comprises a handle (21), a connecting block (23) fixed at the top of the handle (21), and an insertion tube (22) fixed at the top of the connecting block (23); wherein a diversion elbow (24) is fixedly passed through the interior of the connecting block (23), a fixing ring (26) is fixedly disposed at the top end of the connecting block (23), and 6 to 8 buckles (27) arranged in a ring array are fixedly disposed at the top end surface of the fixing ring (26); The end of the probe tube (22) is fixedly connected to a cylinder (210), and the interior of the cylinder (210) is provided with 6-8 drainage tubes (212) in a circular array. The top end port of the diversion bend tube (24) is inserted into the bottom end port of the probe tube (22), and the bottom end port of the diversion bend tube (24) is connected to an end of the negative pressure guide tube (15) away from the negative pressure collection bottle (17) via a pipe joint.

2. A portable uterine cavity cell sampler for reproductive clinical research according to claim 1, characterized in that: Four universal rollers (12) are installed at the four corners of the bottom surface of the body (11) by means of screws, a lifting handle is fixedly connected to the top surface of the body (11), and a support frame (14) is fixedly connected to the left side surface of the body (11).

3. A portable uterine cavity cell sampler for reproductive clinical research according to claim 1, characterized in that: The front area of ​​the machine body (11) is provided with a groove for placing a negative pressure collection bottle (17), and the front surface of the machine body (11) is fixedly connected with a collection bottle bracket (13) clamped with the outer ring surface of the negative pressure collection bottle (17).

4. A portable uterine cavity cell sampler for reproductive clinical research according to claim 1, characterized in that: The outer surface of the handle (21) is provided with a circle of crisscross anti-slip patterns, and the outer surface of the handle (21) is provided with grooves that fit the grip of human fingers.

5. A portable uterine cavity cell sampler for reproductive clinical research according to claim 1, characterized in that: The connection block (23) is provided with a chamber (28) for the diversion bend pipe (24) to pass through and be fixed thereto, and the two ends of the diversion bend pipe (24) respectively pass through the chamber (28), wherein a hook (29) is fixedly connected to the surface of the connection block (23), and the hook (29) is hooked on the support frame (14).

6. A portable uterine cavity cell sampler for reproductive clinical research according to claim 1, characterized in that: 5-7 rubber rings (25) are fixed on the outer ring surface of the top end of the diversion bend pipe (24), and the outer ring surface of the rubber ring (25) is in close contact with the inner wall of the bottom end port of the probe pipe (22).

7. A portable uterine cavity cell sampler for reproductive clinical research according to claim 1, characterized in that: The fixing ring (26) is provided with a circular hole inside for the top end of the diversion bend pipe (24) to pass through, and the top end surface of the fixing ring (26) contacts the bottom end surface of the probe tube (22), wherein 6 to 8 bayonet holes (215) are provided in a circular array on the bottom end surface of the probe tube (22), and the bayonet holes (215) and the buckle (27) are coupled and snap-fitted to each other.

8. A portable uterine cavity cell sampler for reproductive clinical research according to claim 1, characterized in that: A sample circulation cavity (214) penetrating the cylinder (210) is provided inside the probe tube (22), and a sampling port (211) is provided at the top end of the sample circulation cavity (214).

9. A portable uterine cavity cell sampler for reproductive clinical research according to claim 1, characterized in that: The outer surface of the cylinder (210) is provided with 6 to 8 through holes (213) in a circular array for the drainage tube (212) to pass through; wherein the port of the sampling port (211) and the port of the drainage tube (212) are both chamfered, and the outer port of the drainage tube (212) is flush with the outer surface of the cylinder (210).

10. A portable uterine cavity cell sampler for reproductive clinical research according to claim 1, characterized in that: The drainage tubes (212) are located at one end inside the cylinder (210) and are connected to each other, and an opening that is connected to the sample flow cavity (214) is provided in the middle of the drainage tubes (212) after they are connected to each other.

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