Detection device and sample analyzer

Abstract

The invention provides a detection device and a sample analyzer, and relates to the technical field of optical detection equipment. The detection device comprises a base, a bearing assembly, a light source assembly, a PMT assembly and a driver, the bearing assembly is provided with a bearing part, the light source assembly is provided with a calibration end arranged on the bearing assembly, and the PMT assembly is provided with a detection end. The driver drives the movable part of the bearing assembly to be switched between a first state and a second state, when the movable part of the bearing assembly is in the first state, the bearing part is opposite to the detection end, and when the bearing assembly is in the second state, the calibration end is opposite to the detection end. According to the detection device, the bearing part capable of bearing the object to be detected and the calibration end of the light source assembly are arranged on the bearing assembly, so that the detection device can integrate the detection function and the calibration function, switching of the detection function and the calibration function is achieved through movement of the bearing assembly, and therefore the detection device is higher in integration degree and more compact in structure.

Description

Technical Field

[0001] The present application relates to a detection device and a sample analyzer, belonging to the technical field of optical detection equipment. Background Art

[0002] Fluorescence analysis technology can directly or indirectly perform quantitative and qualitative analysis on inorganic and organic compounds, so it has high sensitivity and selectivity and has been widely used. Fluorescence analysis technology can specifically collect fluorescence data through PMT (photomultiplier tube) detection equipment.

[0003] In the related art, the photomultiplier tube in the PMT detection device may have the problem of low detection accuracy, so it is necessary to set up a calibration device connected to the photomultiplier tube to calibrate the photomultiplier tube, which makes the structure of the PMT detection device complex and not compact. Summary of the invention

[0004] The present application provides a detection device and a sample analyzer, which solve the problem that the PMT detection equipment in the related art has a complex and non-compact structure.

[0005] In a first aspect, the present application provides a detection device, comprising:

[0006] Pedestal;

[0007] A bearing assembly, comprising a movable part, the movable part is movably arranged on the base, and the movable part has a bearing portion;

[0008] A light source assembly having a calibration end, wherein the calibration end is arranged on the bearing assembly and is located at one side of the bearing portion;

[0009] A PMT component is arranged on the base, and the PMT component has a detection end;

[0010] A driver connected to the movable member, the driver being configured to drive the movable member to move;

[0011] Wherein, the driver drives the movable part to switch between a first state and a second state. When the movable part is in the first state, the movable part is opposite to the detection end. When the movable part is in the second state, the calibration end is opposite to the detection end.

[0012] In some embodiments, the driver is a motor, the movable part is a turntable, the turntable is rotatably disposed on the base, and the driver is configured to drive the turntable to rotate to the first state or the second state.

[0013] In some embodiments, the supporting assembly further includes a shell, the turntable is a turntable, the shell is disposed on the base, the turntable is rotatably disposed in the shell, and the detection end is located in the shell.

[0014] In some embodiments, a detection channel is provided on the turntable so that the bearing portion is opposite to the detection end.

[0015] In some embodiments, a transmission part is further included, and the transmission part is located on a side of the base facing away from the shell. The turntable has a rotating shaft, and the output end of the driver and the rotating shaft are respectively connected to the transmission part.

[0016] In some embodiments, the light source assembly includes a reference light source unit and an optical fiber line, the reference light source unit is disposed on the base, one end of the optical fiber line is connected to the reference light source unit, the other end of the optical fiber line is passed through the housing and is located inside the housing, and the other end of the optical fiber line is the calibration end;

[0017] The rotary disk is provided with a calibration channel, and when the rotary disk is in the second state, the calibration channel is located between the calibration end and the detection end, so that the calibration end is opposite to the detection end.

[0018] In some embodiments, it also includes an excitation liquid portion, which is arranged above the shell, the excitation liquid portion has an excitation liquid output end, the shell has an input opening opposite to the excitation liquid output end, and the turntable is configured to be rotatable so that the bearing portion is opposite to the input opening.

[0019] In some embodiments, a lifting part is further included, the excitation liquid part is connected to the lifting part, and the lifting part is configured to drive the excitation liquid output end to move toward or away from the base.

[0020] In some embodiments, a light shield is further included, the shell has a limiting groove, the limiting groove is arranged around the input opening, the light shield is connected to the lifting part, and the light shield is configured to be embedded in the limiting groove to cover the input opening inside.

[0021] In some embodiments, a waste liquid collecting portion is further included, which is arranged above the shell and connected to the lifting portion. The waste liquid collecting portion has a collecting end, and the shell has a collecting opening opposite to the collecting end. The turntable is configured to be rotatable so that the supporting portion is opposite to the collecting opening, and the lifting portion is configured to drive the collecting end to move toward or away from the base.

[0022] In some embodiments, the shell is provided with a container installation opening, and the driver is configured to drive the turntable to rotate until the bearing portion is opposite to the container installation opening.

[0023] In some embodiments, the turntable is further provided with an excitation liquid avoidance opening and a collection part avoidance opening, and the turntable is configured to be rotatable so that the excitation liquid avoidance opening is opposite to the excitation liquid output end, or so that the collection part avoidance opening is opposite to the collection end.

[0024] In a second aspect, based on the above detection device, the present application also proposes a sample analyzer, comprising the above detection device.

[0025] In the detection device and sample analyzer proposed in the embodiment of the present application, the detection device includes a bearing assembly, the bearing part of the movable part of the bearing assembly can be used to place the object to be detected, the driver drives the movable part so that the relative position relationship between the movable part and the base can be adjusted, so that the relative position relationship between the bearing part and the base can be adjusted, so that the object to be detected placed on the bearing part can move with the movable part to be opposite to the detection end of the PMT assembly to detect the object to be detected, and the calibration end of the light source assembly can be opposite to the detection end of the PMT assembly to calibrate the PMT assembly by emitting calibration light to the detection end of the PMT assembly through the calibration end. The detection device of the present application can integrate the functions of detection and calibration, and realize the switching of the detection and calibration functions through the movement of the movable part of the bearing assembly, so that the detection device of the present application has a higher degree of integration and a more compact structure. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] The above and other purposes, features and advantages of the embodiments of the present application will become more easily understood through the following detailed description with reference to the accompanying drawings. In the accompanying drawings, multiple embodiments of the present application will be described in an exemplary and non-limiting manner, wherein:

[0027] Figure 1 A three-dimensional diagram of a detection device according to an embodiment of the present application;

[0028] Figure 2 This is a schematic diagram of the internal structure of the carrying component in the detection device of the embodiment of the present application in the first state;

[0029] Figure 3 This is a schematic diagram of the internal structure of the carrying component in the detection device of an embodiment of the present application in the second state;

[0030] Figure 4 A three-dimensional diagram of the bottom side of the detection device according to an embodiment of the present application;

[0031] Figure 5 It is a schematic top view of the movable part of the detection device according to the embodiment of the present application.

[0032] Reference numerals:

[0033] 100-base, 110-base plate, 120-legs,

[0034] 200-carrying assembly, 210-housing, 211-input opening, 212-collecting opening, 213-limiting groove, 214-container mounting opening, 215-boss, 220-turntable, 221-carrying part, 222-rotating shaft, 223-excitation liquid part avoidance opening, 224-collecting part avoidance opening, 225-detection channel, 226-calibration channel,

[0035] 300-light source assembly, 310-reference light source unit, 320-optical fiber line, 321-calibration end,

[0036] 400-PMT assembly, 410-detection end,

[0037] 500-driver, 510-transmission unit,

[0038] 600-excitation liquid part, 610-excitation liquid output end, 620-light shield,

[0039] 700-lifting part,

[0040] 800-waste liquid collection part, 810-collection end. DETAILED DESCRIPTION

[0041] Embodiments of the present application are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present application, and should not be construed as limiting the present application.

[0042] In the description of the present application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0043] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of this application, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0044] In this application, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, an electrical connection, or communication with each other; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0045] In the present application, unless otherwise clearly specified and limited, a first feature being “above” or “below” a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being “above”, “above”, and “above” a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being “below”, “below”, and “below” a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0046] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present application. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0047] Fluorescence analysis technology can directly or indirectly perform quantitative and qualitative analysis on inorganic and organic compounds, so it has high sensitivity and selectivity and has been widely used. Fluorescence analysis technology can specifically collect fluorescence data through PMT (photomultiplier tube) detection equipment.

[0048] In the related art, the photomultiplier tube in the PMT detection device may have the problem of low detection accuracy, so it is necessary to set up a calibration device connected to the photomultiplier tube to calibrate the photomultiplier tube, which makes the structure of the PMT detection device complex and not compact.

[0049] In the detection device proposed in the embodiment of the present application, the bearing part of the movable part of the bearing assembly can be used to place the object to be detected, and the driver drives the movable part so that the relative position relationship between the movable part and the base can be adjusted, thereby making the relative position relationship between the bearing part and the base adjustable, so that the object to be detected placed on the bearing part can move with the movable part to be opposite to the detection end of the PMT assembly to detect the object to be detected, and the calibration end of the light source assembly can be opposite to the detection end of the PMT assembly to calibrate the PMT assembly by emitting calibration light to the detection end of the PMT assembly through the calibration end. The detection device of the present application can integrate the functions of detection and calibration, and realize the switching of the detection and calibration functions through the movement of the movable part of the bearing assembly, so that the detection device of the present application has a higher degree of integration and a more compact structure.

[0050] The detection device and sample analyzer provided in the present application are described in detail below in conjunction with specific embodiments.

[0051] The present application embodiment proposes a detection device, referring to Figure 1-Figure 3 As shown, it includes a base 100, a carrying assembly 200, a PMT assembly 400 and a driver 500. The detection device can be used to detect the reagent to be detected and can perform optical calibration on the PMT assembly 400.

[0052] Among them, the housing 210 is the basic component of the detection device of the present application, and the housing 210 can provide an installation foundation for other at least some components of the detection device. The bearing assembly 200 is arranged on the base 100, and a bearing part 221 is arranged on the bearing assembly 200. The object to be detected, such as a reagent to be detected, can be arranged on the bearing part 221. Specifically, the reagent to be detected can be placed in a container such as a test tube, and the container such as a test tube can be placed on the bearing part 221 of the bearing assembly 200. The light source assembly 300 can emit a calibration light source. Specifically, the light source assembly 300 has a calibration end 321, and the light source assembly 300 can emit a calibration light through the calibration end 321. The calibration end 321 of the light source assembly 300 is arranged on the bearing assembly 200 and is located on one side of the bearing part 221, so that the calibration end 321 and the bearing part 221 are distributed at different parts of the bearing assembly 200.

[0053] The PMT assembly 400 is arranged on the base 100, and the detection end 410 of the PMT assembly 400 is located on one side of the carrier assembly 200. The PMT assembly 400 is specifically a photomultiplier tube assembly. The PMT assembly 400 can directly or indirectly perform quantitative and qualitative analysis on the object to be detected using fluorescence analysis technology. Specifically, the PMT assembly 400 has a detection end 410, and the detection end 410 of the PMT assembly 400 can receive a signal emitted by the object to be detected. Specifically, by mixing the object to be detected with the excitation liquid, the object to be detected itself can generate a weak light signal, and the detection end 410 of the PMT assembly can receive the light signal generated by the object to be detected, and compare the light signal with the signal in the database, so as to analyze the object to be detected.

[0054] At least part of the bearing assembly 200 is movably connected to the base 100. Specifically, the bearing assembly 200 includes a movable part, which can be a movable part such as a turntable or a slider. The movable part is movably connected to the base 100, and the bearing part 221 is located on the movable part. The driver 500 is connected to the movable part, so the driver 500 can drive the movable part to move relative to the base 100, thereby driving the bearing part 221 located on the movable part to move relative to the base 100, so that the relative position relationship between the bearing part 221 and the base 100 can be changed. When the driver 500 drives the movable part to move relative to the base 100, the base 100 can switch between the first state and the second state. When the movable part is in the first state, the bearing part 221 of the movable part is opposite to the detection end 410 of the PMT assembly 400. If a container loaded with the object to be detected is placed on the bearing part 221, the container loaded with the object to be detected can be opposite to the detection end 410 of the PMT assembly 400, so that the object to be detected can be opposite to the detection end 410 of the PMT assembly 400. At this time, the PMT can be started to detect the object to be detected. When the movable part is in the second state, the calibration end 321 of the light source assembly 300 can be opposite to the detection end 410 of the PMT assembly 400. At this time, if both the light source assembly 300 and the PMT assembly 400 are started, the calibration end 310 of the light source assembly 300 can emit calibration light to the detection end 410 of the PMT assembly 400, thereby achieving the purpose of calibrating the PMT assembly 400.

[0055] When the detection device of the present application is used to detect the object to be detected, the movable part of the carrier assembly 200 can be driven to rotate by the driver 500 first, so that the movable part is switched to the second state, so that the calibration end 321 of the light source assembly 300 and the detection end 410 of the PMT assembly 400 are relative, so that the PMT assembly 400 is detected and calibrated. If the PMT assembly 400 has reached the use requirements or reached the use requirements after manual adjustment, the movable part of the carrier assembly 200 is driven to rotate by the driver 500, so that the movable part is switched to the first state, so that the object to be detected located at the bearing part 221 of the movable part can be relative to the detection end 410 of the PMT assembly 400, so as to complete the detection of the object to be detected. In addition, it should be understood that the object to be detected can be placed on the bearing part 221 of the movable part before the PMT assembly 400 is calibrated, or placed on the bearing part 221 of the movable part after the PMT assembly 400 is calibrated, and this application is not limited thereto.

[0056] In some embodiments, reference Figure 1-Figure 3 As shown, the movable part of the supporting component 200 of the present application is a turntable 220, and the turntable 220 is rotatably connected to the base 100. Accordingly, the supporting portion 221 can be distributed on the supporting component 200 other than its rotating portion. The driver 500 can adopt a motor, and the output end of the motor is connected to the turntable 220 to drive the turntable 220 to rotate, so that the object to be detected placed on the supporting portion 221 can be rotated to be opposite to the detection end 410 of the PMT component 400.

[0057] Specifically, the rotation connection between the turntable 220 and the base 100 can be set at the center of the turntable 220, and the bearing part 221 is set away from the center of the bearing assembly 200. The driver 500 drives the turntable 220 to rotate at different angles so that the bearing part 221 and the calibration end 321 of the light source assembly 300 are respectively opposite to the detection end 410 of the PMT assembly 400. The turntable 220 can be a disk structure. Since the turntable 220 is rotatably connected to the base 100, the relative position relationship between the turntable 220 itself and the base 100 will not change during the rotation of the bearing assembly 200 relative to the base 100, and only the relative position relationship between the bearing part 221 set on the turntable 220 and the base 100 will change. In this way, when the turntable 220 switches between the first state and the second state, the space range occupied by the turntable 220 on the base 100 does not change much, so that the detection device of the present application has a relatively compact structure in various states.

[0058] In addition, in other embodiments, the movable member of the present application may also be configured to be movably connected to the base 100, so that the movable member can reciprocate relative to the base 100, and accordingly, the driver 500 may drive the movable member to move to the first state or the second state, so that the bearing portion 221 and the calibration end 321 are respectively opposite to the detection end 410. Specifically, the bearing portion 221 and the calibration end 321 provided on the movable member may be located on the same side of the detection end 410, and the driver 500 drives the movable member to move in a linear direction, so that the bearing portion 221 or the calibration end 321 is opposite to the detection end 410.

[0059] In some embodiments, the bearing assembly 200 of the present application may further include a housing 210, wherein the housing 210 may be fixedly disposed on the base 100, the housing 210 has a cavity, and the turntable 220 is disposed in the cavity of the housing 210. The turntable 220 is connected to the driver 500, and the driver 500 may drive the turntable 220 to rotate. The bearing portion 221 of the bearing assembly 200 is disposed on the turntable 220, and the driver 500 drives the turntable 220 to rotate so that the bearing assembly 200 switches between the first state and the second state. The turntable 220 is specifically a disc structure, and accordingly, the inner cavity of the housing 210 is a cylindrical cavity structure, and the outer edge of the turntable 220 may contact the inner wall of the housing 210 or have a small gap, so that when the driver 500 drives the turntable 220 to rotate, the inner wall of the housing 210 may limit the turntable 220, so that the turntable 220 has a higher rotation accuracy.

[0060] The turntable 220 is arranged in the housing 210, and the housing 210 can also cover the bearing part 221 of the bearing assembly 200 therein. The housing 210 can have an opening for the PMT assembly 400 to pass through, and the detection end 410 of the PMT assembly 400 can extend into the housing 210 through the opening of the housing 210. The object to be detected placed on the bearing part 221, the calibration end 321 of the light source assembly 300, and the detection end 410 of the PMT assembly 400 are all located in the housing 210. When the PMT assembly 400 detects the object to be detected and the light source assembly 300 calibrates the PMT assembly 400, the detection and calibration processes are all implemented in the housing 210, and the housing 210 can shield external light to a certain extent, thereby reducing the interference of external light on the detection result of the object to be detected and the calibration result of the PMT assembly 400, so as to make the detection accuracy of the object to be detected and the calibration accuracy of the PMT assembly 400 higher.

[0061] The bottom end of the housing 210 can be arranged on the base 100, and the top end of the housing 210 is provided with an opening communicating with the inner cavity of the housing 210 and a movable top cover, and the top cover can open and close the opening at the top end of the housing 210, so that by opening the top cover of the housing 210, the user can also inspect and maintain the turntable 220 arranged in the housing 210 and the calibration end 321 of the light source assembly 300. The top cover of the housing 210 can be connected to the housing 210 in a rotatable manner.

[0062] In some embodiments, reference Figure 2-Figure 4 As shown, the detection device of the present application may also be provided with a transmission part 510, and the transmission part 510 is connected to both the driver 500 and the turntable 220, so that the driver 500 can drive the turntable 220 to rotate through the transmission part 510, and the driver 500 is connected to the turntable 220 through the transmission part 510, which can avoid direct contact between the driver 500 and the turntable 220, thereby reducing the loss of the output end of the driver 500. The transmission part 510 can adopt a pulley structure, specifically, the transmission part 510 can include a first pulley, a second pulley and a rotating belt, the turntable 220 can be provided with a rotating shaft 222, the rotating shaft 222 can extend out of the housing 210, the first transmission wheel is connected to the output end of the driver 500, the second transmission wheel is connected to the rotating shaft 222, and the transmission belt is sleeved on the first transmission wheel and the second transmission wheel. When the driver 500 drives the first transmission wheel to rotate, the second transmission wheel can be driven by the transmission belt to make the turntable 220 rotatable.

[0063] Of course, the transmission part 510 may also adopt a gear structure. Specifically, the transmission part 510 may include a first gear and a second gear. The first gear is connected to the output end of the driver 500, and the second gear is connected to the rotating shaft 222. The first gear and the second gear are meshed. After the driver 500 drives the first gear to rotate, it can drive the second gear to rotate, so that the rotating disk 220 can rotate.

[0064] In some embodiments, reference Figure 4 As shown, in order to further make the structure of the detection device of the present application compact, it can be achieved by making full use of the available installation space on the base 100. Specifically, the bearing assembly 200 can be arranged on the upper side of the base 100, the driver 500 can be arranged on the upper side of the base 100 and on one side of the bearing assembly 200, and the transmission part 510 can be arranged on one side of the bottom of the base 100, so that the transmission part 510 and the driver 500 are distributed on the opposite sides of the base 100, and the transmission part 510 and the bearing assembly 200 are also distributed on the opposite sides of the base 100, so that the opposite sides of the base 100 can be used to install the components of the detection device, and accordingly, the surface area of ​​one side of the base 100 does not need to be set too large, so that the base 100 and the detection device of the present application have a compact structure.

[0065] Specifically, the driver 500 can be set upside down on the base 100, the output end of the driver 500 is passed through the base 100 and extends to the bottom side of the base 100, and the rotating shaft 222 is also passed through the base 100 and extends to the bottom side of the base 100, so that the transmission part 510 located on the bottom side of the base 100 can be connected to both the output end of the driver 500 and the rotating shaft 222.

[0066] In some embodiments, reference Figure 2 and Figure 3 As shown, the light source assembly 300 in the present application includes a reference light source unit 310 and an optical fiber line 320, wherein the reference light source unit 310 is the main component of the light source assembly 300, and the reference light source unit 310 can generate reference light. One end of the optical fiber line 320 can be connected to the output end of the reference light source unit 310, and the other end of the optical fiber line 320 is the calibration end 321 of the light source assembly 300, so the other end of the optical fiber line 320 can be inserted into the housing 210 and fixed in the housing 210. Specifically, the turntable 220 can be provided with a calibration channel 226, and when the turntable 220 is in the first state, part of the turntable 220 is located between the calibration end 321 and the detection end 410 to block the calibration end 321 and the detection end 410, so that the light emitted by the calibration end 321 can be blocked by the turntable 220. When the turntable 220 is in the second state, the calibration channel 226 of the turntable 220 is located between the calibration end 321 and the detection end 410, so that the calibration end 321 and the detection end 410 can be connected, so that the calibration end 321 is opposite to the detection end 410, and the light emitted by the calibration end 321 can pass through the calibration channel 226 and be received by the detection end 410.

[0067] exist Figure 2 and Figure 3 In the illustrated embodiment, a boss 215 is provided on the side of the bottom wall of the housing 210 facing the turntable 220, and a slot that cooperates with the boss 215 is provided on the turntable 220, and the boss 215 extends into the slot. In this way, when the driver 500 drives the turntable 220 to rotate, the outer wall of the boss 215 can limit the turntable 220, so that the turntable 220 can rotate more accurately. The calibration end 321 of the optical fiber line 320 is fixed on the boss 215. When the turntable 220 rotates to a position where the calibration end 321 is opposite to the detection end 410, that is, the calibration channel 226 is located between the calibration end 321 and the detection end 410, the light emitted by the calibration end 321 can pass through the calibration channel 226 and be received by the detection end 410.

[0068] By setting the optical fiber line 320, the calibration end 321 of the light source assembly 300 can be set more flexibly, so that the main reference light source part 310 of the light source assembly 300 does not need to be set on the turntable 220, thereby reducing the weight of the components carried on the turntable 220. Correspondingly, the overall weight of the components that need to be driven by the driver 500 is relatively smaller, so that the driver 500 does not need to adopt a large driving force and high-power model, thereby reducing the cost of the detection device of the present application.

[0069] refer to Figure 2 and Figure 4 As shown, the base 100 may specifically include a substrate 110 and a support leg 120, wherein the support leg 120 is arranged on the bottom side of the substrate 110 to support the substrate 110, the driver 500, the bearing assembly 200 and the PMT assembly 400 may be arranged on the side of the substrate 110 facing away from the support leg 120, the reference light source unit 310 may be arranged on the support leg 120, and the optical fiber line 320 may extend from the support leg 120 to the substrate 110, so that the reference light source unit 310 will not occupy the available installation space on the substrate 110, so that the structure of the detection device of the present application is compact.

[0070] In some embodiments, reference Figure 1 and Figure 2 As shown, the detection device of the present application may also be provided with an excitation liquid section 600, which can input excitation liquid into the object to be detected, so that the detection result after the PMT assembly 400 detects the object to be detected is clearer and more accurate. Among them, the excitation liquid section 600 has an excitation liquid output end 610, and the excitation liquid section 600 can output the excitation liquid through the excitation liquid output end 610. The excitation liquid section 600 can be arranged on the top side of the shell 210, so that the excitation liquid output end 610 is also located on the top side of the shell 210. An input opening 211 is provided on the top side of the shell 210, and the input opening 211 of the shell 210 is arranged opposite to the excitation liquid output end 610 of the excitation liquid section 600, so that the excitation liquid output by the excitation liquid output end 610 can fall into the shell 210 through the input opening 211 of the shell 210 under the action of its own gravity.

[0071] When the driver 500 drives the turntable 220 to rotate, the driver 500 can also drive the turntable 220 to rotate until the bearing part 221 is opposite to the input opening 211, so that the excitation liquid falls into the housing 210 through the input opening 211 and can fall into the object to be detected in the bearing part 221, so that the excitation liquid can be mixed with the object to be detected. Specifically, it can be arranged that when the turntable 220 rotates to the bearing part 221 and is opposite to the detection end 410 of the PMT assembly 400, the bearing part 221 can also be opposite to the input opening 211 of the housing 210, so that the excitation liquid can be added to the object to be detected in the bearing part 221 through the excitation liquid part 600, and then the PMT assembly 400 can detect the object to be detected.

[0072] In the present application, the supporting portion 221 on the turntable 220 can be specifically configured as a receiving groove opened on the turntable 220, and a container for loading the object to be detected, such as a test tube, can be placed in the receiving groove of the turntable 220, and the opening of the receiving groove is located at the top of the receiving groove, and the top opening of the receiving groove can be opposite to the input opening 211 of the shell 210, so that the test tube can be placed into the receiving groove through the opening of the receiving groove, and the top opening of the test tube can be arranged opposite to the input opening 211 of the shell 210, so that the excitation liquid part 600 can input the excitation liquid into the test tube through the input opening 211. The receiving groove of the turntable 220 can be set adjacent to the edge of the turntable 220, and the side wall of the turntable 220 can also be set with a detection channel 225 connected to the receiving groove. The detection channel 225 of the turntable 220 can be rotated to between the detection end 410 of the PMT component 400 and the receiving groove, so that the receiving groove and the detection end 410 can be connected, so that the detection end 410 of the PMT component 400 is opposite to the receiving groove, so that the PMT component 400 can be opposite to the test tube placed in the receiving groove to detect the object to be detected in the test tube.

[0073] The top opening of the test tube may be arranged close to the input opening 211 of the housing 210 , so that the excitation liquid can fall into the test tube more accurately and mix with the object to be detected after falling into the housing 210 through the input opening 211 .

[0074] The shell 210 may also have a container installation opening 214, and the container loaded with the object to be detected can be inserted into the bearing part 221 of the turntable 220 through the container installation opening 214 of the shell 210. Specifically, the driver 500 can drive the turntable 220 to rotate until the bearing part 221 is opposite to the container installation opening 214.

[0075] In some embodiments, reference Figure 1 and Figure 2As shown, in order to allow the excitation liquid output by the excitation liquid unit 600 to be more accurately injected into the test tube and mixed with the object to be detected, the detection device of the present application may also be provided with a lifting unit 700, which is connected to the excitation liquid unit 600, and the lifting unit 700 is configured to drive the excitation liquid output end 610 of the excitation liquid unit 600 to move toward the base 100 or away from the base 100. When the turntable 220 rotates to the bearing portion 221 and the input opening 211 of the housing 210, the lifting unit 700 drives the excitation liquid output end 610 of the excitation liquid unit 600 to move toward the base 100 so that the excitation liquid output end 610 can be close to the input opening 211 of the housing 210. The lifting part 700 continues to drive the excitation liquid output end 610 to move toward the base 100, so that the excitation liquid output end 610 can extend into the shell 210 through the input opening 211 of the shell 210, until the excitation liquid output end 610 extends into the test tube, and the excitation liquid part 600 can inject the excitation liquid into the test tube through the excitation liquid output end 610. In this way, it can be ensured that the excitation liquid output by the excitation liquid part 600 completely falls into the test tube and mixes with the object to be detected, and prevents the excitation liquid from spilling outside the test tube. After the injection of the excitation liquid into the test tube is completed, the object to be detected can be detected through the PMT assembly 400.

[0076] When the PMT assembly 400 completes the detection of the object to be detected, the lifting portion 700 can drive the excitation liquid portion 600 to move in a direction away from the base 100, so that the excitation liquid output end 610 of the excitation liquid portion 600 moves out of the test tube and out of the shell 210, so that the excitation liquid output end 610 of the excitation liquid portion 600 will not interfere with the shell 210.

[0077] In some embodiments, it should be understood that, since the top of the housing 210 is provided with an input opening 211, in order to prevent external light from entering the housing 210 through the input opening 211 and interfering with the detection result of the PMT assembly 400 detecting the object to be detected, reference Figure 1 and Figure 2 As shown, the detection device of the present application may also be provided with a light shield 620. The light shield 620 is connected to the lifting part 700. When the lifting part 700 drives the excitation liquid part 600 to move toward the base 100 or away from the base 100, the light shield 620 may also move toward the base 100 or away from the base 100 with the lifting part 700. After the lifting part 700 drives the excitation liquid part 600 to move toward the base 100, the light shield 620 may move toward the housing 210, so that the light shield 620 covers the input opening 211 of the housing 210, so that the light shield 620 can shield external light, so that the external light cannot enter the housing 210 through the input opening 211 of the housing 210.

[0078] Specifically, the light shield 620 can be set on the excitation liquid output end 610 of the excitation liquid part 600. When the lifting part 700 drives the excitation liquid output end 610 to extend into the test tube, the light shield 620 can just cover the input opening 211 of the shell 210. The shell 210 can also be provided with a limiting groove 213, which can be arranged around the input opening 211. When the light shield 620 is covered on the input opening 211, the end of the light shield 620 can be embedded in the limiting groove 213, so that the light shield 620 is stably connected to the shell 210, and at the same time, the external light can be further blocked outside the light shield 620.

[0079] In some embodiments, it should be understood that after the detection of the objects to be detected in the test tubes placed in the carrying portion 221 of the turntable 220 is completed, the objects to be detected need to be collected and processed in a centralized manner to prevent contamination of the objects to be detected. Figure 1 and Figure 2 As shown, the detection device of the present application may also be provided with a waste liquid collection part 800, wherein the waste liquid collection part 800 is arranged on the top side of the housing 210, and the waste liquid collection part 800 has a collection end 810, through which the waste liquid collection part 800 can absorb the object to be detected, and the waste liquid collection part 800 can be arranged on the top side of the housing 210, so that the collection end 810 is also located on the top side of the housing 210. The top side of the housing 210 is provided with a collection opening 212, and the collection opening 212 of the housing 210 is arranged opposite to the collection end 810 of the waste liquid collection part 800. When the detection of the object to be detected is completed, the driver 500 can drive the turntable 220 to rotate, so that the turntable 220 rotates to the bearing part 221 and is opposite to the collection opening 212, so that the collection end 810 of the waste liquid collection part 800 can absorb the object to be detected that has been detected in the test tube arranged on the bearing part 221.

[0080] The lifting part 700 is connected to the waste liquid collecting part 800, and the lifting part 700 is configured to drive the collecting end 810 of the waste liquid collecting part 800 to move toward the base 100 or away from the base 100. When the turntable 220 rotates to the bearing part 221 and is opposite to the collecting opening 212 of the shell 210, the lifting part 700 drives the collecting end 810 of the waste liquid collecting part 800 to move toward the base 100 so that the collecting end 810 can be close to the collecting opening 212 of the shell 210. The lifting part 700 continues to drive the collecting end 810 to move toward the base 100 so that the collecting end 810 passes through the collecting opening 212 of the shell 210 and extends into the shell 210, until the collecting end 810 extends into the test tube, and the waste liquid collecting part 800 can absorb the object to be detected in the test tube through the collecting end 810.

[0081] When the waste liquid collecting part 800 completes the object to be detected in the test tube, the lifting part 700 can drive the waste liquid collecting part 800 to move in the direction away from the base 100, so that the collecting end 810 of the waste liquid collecting part 800 is moved out of the test tube and out of the shell 210. In this way, the collecting end 810 of the waste liquid collecting part 800 will not interfere with the shell 210, and the user can open the top cover of the shell 210 to take and place the test tube on the carrying part 221 to replace the object to be detected.

[0082] It should be understood that since the excitation liquid section 600 and the waste liquid collection section 800 are both arranged on the lifting section 700, when the lifting section 700 drives the excitation liquid section 600 or the waste liquid collection section 800 to move up and down, the excitation liquid section 600 and the waste liquid collection section 800 will be lifted and lowered at the same time. In order to avoid the excitation liquid section 600 and the waste liquid collection section 800 from interfering with the turntable 220, refer to Figure 5 As shown, the turntable 220 may also be provided with an exciting liquid portion avoidance opening 223 and a collecting portion avoidance opening 224, and the housing 210 is provided with an opening structure corresponding to the exciting liquid portion avoidance opening 223 and the collecting portion avoidance opening 224 of the turntable 220. Specifically, when the bearing portion 221 of the turntable 220 is opposite to the input opening 211, after the lifting portion 700 drives the exciting liquid portion 600 and the waste liquid collecting portion 800 to move toward the turntable 220 at the same time, the collecting end 810 of the waste liquid collecting portion 800 may be arranged through the collecting opening 212 of the housing and extend into the collecting portion avoidance opening 224 of the turntable. When the supporting part 221 of the turntable 220 is opposite to the collecting opening 212, after the lifting part 700 drives the excitation liquid part 600 and the waste liquid collecting part 800 to move toward the turntable 220 at the same time, the excitation liquid output end 610 of the excitation liquid part 600 can be passed through the input opening 212 of the shell and extend into the excitation liquid part avoidance port 223 of the turntable.

[0083] Based on the above detection device, an embodiment of the present application further proposes a sample analyzer, including the above detection device.

[0084] Finally, it should be noted that the above implementation modes are only used to illustrate the technical solutions of the present application, rather than to limit it. Although the present application has been described in detail with reference to the aforementioned implementation modes, a person of ordinary skill in the art should understand that the technical solutions described in the aforementioned implementation modes can still be modified, or some or all of the technical features therein can be replaced by equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the implementation modes of the present application.

Claims

1. A detection device, characterized in that: include Pedestal; A bearing assembly, comprising a movable part, the movable part is movably arranged on the base, and the movable part has a bearing portion; A light source assembly having a calibration end, wherein the calibration end is arranged on the bearing assembly and is located at one side of the bearing portion; A PMT component is arranged on the base, and the PMT component has a detection end; A driver connected to the movable member, the driver being configured to drive the movable member to move; Wherein, the driver drives the movable part to switch between a first state and a second state. When the movable part is in the first state, the bearing part is opposite to the detection end. When the movable part is in the second state, the calibration end is opposite to the detection end.

2. The detection device according to claim 1, characterized in that: The driver is a motor, the movable part is a turntable, the turntable is rotatably disposed on the base, and the driver is configured to drive the turntable to rotate to the first state or the second state.

3. The detection device according to claim 2, characterized in that: The bearing assembly further comprises a shell, the shell is arranged on the base, the turntable is rotatably arranged in the shell, and the detection end is located in the shell.

4. The detection device according to claim 3, characterized in that: The rotating disk is provided with a detection channel so that the bearing portion is opposite to the detection end.

5. The detection device according to claim 3, characterized in that: It also includes a transmission part, which is located on the side of the base facing away from the shell. The turntable has a rotating shaft, and the output end of the driver and the rotating shaft are respectively connected to the transmission part.

6. The detection device according to claim 3, characterized in that: The light source assembly comprises a reference light source unit and an optical fiber line, wherein the reference light source unit is arranged on the base, one end of the optical fiber line is connected to the reference light source unit, the other end of the optical fiber line is passed through the housing and is located inside the housing, and the other end of the optical fiber line is the calibration end; The turntable is provided with a calibration channel. When the turntable is in the second state, the calibration channel is located between the calibration end and the detection end so that the calibration end is opposite to the detection end.

7. The detection device according to any one of claims 3 to 6, characterized in that: It also includes an excitation liquid portion, which is arranged above the shell, the excitation liquid portion has an excitation liquid output end, the shell is provided with an input opening opposite to the excitation liquid output end, and the turntable is configured to be rotatable so that the bearing portion is opposite to the input opening.

8. The detection device according to claim 7, characterized in that: It also includes a lifting part, the excitation liquid part is connected to the lifting part, and the lifting part is configured to drive the excitation liquid output end to move toward or away from the base.

9. The detection device according to claim 8, characterized in that: It also includes a light shield, the shell is provided with a limiting groove, the limiting groove is arranged around the input opening, the light shield is connected to the lifting part, and the light shield is configured to be embedded in the limiting groove to cover the input opening inside.

10. The detection device according to claim 8, characterized in that: It also includes a waste liquid collecting part, which is arranged above the shell and connected to the lifting part. The waste liquid collecting part has a collecting end, and the shell is provided with a collecting opening opposite to the collecting end. The turntable is configured to be rotatable so that the bearing part is opposite to the collecting opening, and the lifting part is configured to drive the collecting end to move toward or away from the base.

11. The detection device according to claim 10, characterized in that: The turntable is also provided with an excitation liquid avoidance opening and a collection part avoidance opening, and the turntable is configured to be rotatable until the excitation liquid avoidance opening is opposite to the excitation liquid output end, or to be rotated until the collection part avoidance opening is opposite to the collection end.

12. The detection device according to claim 3, characterized in that: The shell is provided with a container installation opening, and the driver is configured to drive the turntable to rotate until the bearing portion is opposite to the container installation opening.

13. A sample analyzer, characterized in that: Comprising a detection device as described in any one of claims 1-12.

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