Dry suspending agent as well as preparation method and application thereof

Abstract

The invention relates to the technical field of pesticides, and provides a dry suspending agent as well as a preparation method and application thereof. The dry suspending agent comprises the following components in parts by weight: 25-80 parts of an active component, 10-15 parts of a first wetting dispersant and 3-8 parts of a second wetting dispersant. According to the dry suspending agent, through compounding of the first wetting dispersant and the second wetting dispersant, the dispersion effect of the wetting dispersants is effectively improved, the dispersity of active ingredients in the dry suspending agent is improved, and the pesticide effect of the dry suspending agent is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of pesticides, and in particular to a dry suspension concentrate and a preparation method and application thereof. Background Art

[0002] The application of pesticides has made great contributions to promoting crop yields, improving the quality of crop products, and reducing labor intensity. How to ensure that the yield and quality of crops at this stage are not affected while reducing the amount and frequency of pesticide use has become a problem that must be solved. Exploring high-efficiency and low-toxic pesticide formulations is one of the directions to solve this problem, and dry suspension concentrates are a type of pesticide formulation that is beneficial to improving the efficacy of pesticides and reducing the amount and frequency of pesticide use. Dry suspension concentrates refer to a type of formulation whose particles can quickly disintegrate and disperse in water to form an aqueous suspension after being placed in water. As a new type of environmentally friendly formulation, dry suspension concentrates have many application characteristics, such as rapid disintegration in water, good dispersibility, high suspension, fine liquid particles, resistance to rain erosion, improved efficacy, and environmental friendliness. In addition, compared with traditional pesticide formulations, the production environment of dry suspension concentrates has been greatly improved, reducing dust pollution.

[0003] The particle size and efficacy of pesticide formulations, including dry suspensions, are positively correlated to a certain extent: for example, on the same leaf area, the smaller the particle size of the pesticide, the greater the amount attached to the leaf, and the greater the amount that can enter the plant or insect body through the stomata, and the better the efficacy. Therefore, research on nano-level pesticide formulation products can reduce the amount of pesticides used and improve the efficacy of pesticides. Nanopesticides refer to pesticide formulations that, based on certain pest control scenarios, use functional materials and nanotechnology to make the active ingredients of pesticides stably exist in a nanoscale dispersed state in the formulation and use dispersion system, and can exert application performance different from the original formulation when used. Nanopesticides have the characteristics of small particles, are easily absorbed by target pests or plants, and have the advantages of high efficacy and low dosage.

[0004] Unfortunately, in the prior art, the particle size of water-based pesticide formulations such as dry suspensions is relatively large, and the particle size is basically above 10 microns. The particle size of very few products can reach 5 to 10 microns, which is far from reaching the nanometer level. This results in the efficacy of the pesticide in the dry suspension being limited by the particle size. Therefore, it is urgent to provide a pesticide formulation with a smaller particle size. Summary of the invention

[0005] The purpose of the present application is to provide a dry suspension concentrate and a preparation method and application thereof, so as to solve the technical problem that after the dry suspension concentrate is dispersed in the prior art, the particle size in the obtained suspension is large, which affects the efficacy of the pesticide.

[0006] In order to achieve the above application purpose, the technical solution adopted in this application is as follows:

[0007] In the first aspect, the embodiment provides a dry suspension. The dry suspension of the embodiment of the present application comprises the following components in parts by weight:

[0008] Active ingredient 25-80 parts

[0009] 10-15 parts of the first wetting and dispersing agent

[0010] 3 to 8 parts of the second wetting and dispersing agent.

[0011] Wherein, the first wetting and dispersing agent includes at least one of sodium dodecylbenzene sulfonate, HDB-1904x, HDB-1903, MorwetEFW, Morwet IP, Petro AA, 207k, DS6008, Morwet D425, Agrilan700, Winst 3117, Winst3118, SP-DF2238, SP-DF2258, and GY-D800; and / or

[0012] The second wetting and dispersing agent includes at least one of F608, MF605, Hostaphat 1306, AA4145, OROTAN731A, OROTAN963, and OROTAN1124.

[0013] The dry suspension concentrate of the embodiment of the present application is compounded between the first wetting dispersant and the second wetting dispersant, which greatly improves the dispersing effect on the active ingredients of the pesticide in the dry suspension concentrate, improves the dispersibility of the active ingredients in the dry suspension concentrate, and enables the dry suspension concentrate particles to quickly disintegrate and disperse to form a suspension after being dispersed in a solvent such as water, and the particle size of the particles in the formed suspension is very small, even reaching the nanometer level, thereby effectively improving the efficacy of the pesticide in the dry suspension concentrate.

[0014] In a second aspect, the present invention provides a method for preparing the above dry suspension concentrate. The method for preparing the dry suspension concentrate in the present invention comprises the following steps:

[0015] The active ingredient, the first wetting and dispersing agent, the second wetting and dispersing agent and the solvent are mixed and ground to obtain a mixed slurry;

[0016] The mixed slurry is dried to obtain a dry suspension.

[0017] The dry suspension preparation method of the embodiment of the present application controls the content of the first wetting dispersant, the second wetting dispersant and the active component within a specific range, so that the active component can be well dispersed in the mixed slurry, and a dry suspension with good dispersibility of the active component is obtained after subsequent drying treatment. In addition, the preparation method of the embodiment of the present application has fewer process steps, controllable process parameters, less dust pollution during the preparation process, high production efficiency, and is conducive to large-scale industrial production.

[0018] In a third aspect, the embodiments of the present application provide the use of the dry suspension concentrate described above in the control of crop diseases and insect pests.

[0019] Based on the good dispersibility of the active components in the dry suspension concentrate of the embodiment of the present application, the small particle size after being made into a suspension, the large amount of active components attached to the plant surface, and the high utilization rate of the active components, the dry suspension concentrate of the embodiment of the present application has a good effect on the prevention and control of crop diseases and insect pests. DETAILED DESCRIPTION

[0020] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present application more clearly understood, the present application is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0021] In this application, the term "and / or" describes the association relationship of associated objects, indicating that there may be three relationships. For example, A and / or B can mean: A exists alone, A and B exist at the same time, and B exists alone. A and B can be singular or plural. The character " / " generally indicates that the associated objects are in an "or" relationship.

[0022] In this application, "at least one" means one or more, and "plurality" means two or more. "At least one of the following" or similar expressions refers to any combination of these items, including any combination of single items or plural items. For example, "at least one of a, b, or c", or "at least one of a, b, and c" can all mean: a, b, c, a~b (i.e. a and b), a~c, b~c, or a~b~c, where a, b, c can be single or multiple, respectively.

[0023] It should be understood that in the various embodiments of the present application, the size of the serial numbers of the above-mentioned processes does not mean the order of execution, some or all of the steps can be executed in parallel or sequentially, and the execution order of each process should be determined by its function and internal logic, and should not constitute any limitation on the implementation process of the embodiments of the present application.

[0024] The terms used in the embodiments of the present application are only for the purpose of describing specific embodiments, and are not intended to limit the present application. The singular forms "a", "an" and "the" used in the embodiments of the present application and the appended claims are also intended to include plural forms, unless the context clearly indicates other meanings.

[0025] The weight of the relevant components mentioned in the embodiment description of the present application can not only refer to the specific content of each component, but also represent the proportional relationship between the weights of the components. Therefore, as long as the content of the relevant components is proportionally enlarged or reduced according to the embodiment description of the present application, it is within the scope disclosed in the embodiment description of the present application. Specifically, the mass in the embodiment description of the present application can be μg, mg, g, kg and other mass units known in the chemical industry.

[0026] The terms "first" and "second" are used only for descriptive purposes to distinguish objects such as substances from each other, and should not be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features. For example, without departing from the scope of the embodiments of the present application, the first XX may also be referred to as the second XX, and similarly, the second XX may also be referred to as the first XX. Thus, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features.

[0027] In order to solve the technical problem that after the pesticide dry suspension is dispersed in the prior art, the particle size in the obtained suspension is large, resulting in limited efficacy of the pesticide active ingredients, the present application proposes the following technical solution.

[0028] In the first aspect, the present invention provides a dry suspension concentrate. The dry suspension concentrate of the present invention comprises the following components in parts by weight:

[0029] Active ingredient 25-80 parts

[0030] 10-15 parts of the first wetting and dispersing agent

[0031] 3 to 8 parts of the second wetting and dispersing agent.

[0032] Wherein, the first wetting and dispersing agent includes at least one of sodium dodecylbenzene sulfonate, HDB-1904x, HDB-1903, MorwetEFW, Morwet IP, Petro AA, 207k, DS6008, Morwet D425, Agrilan 700, Winst 3117, Winst3118, SP-DF2238, SP-DF2258, and GY-D800; and / or

[0033] The second wetting and dispersing agent includes at least one of F608, MF605, Hostaphat 1306, AA4145, OROTAN731A, OROTAN963, and OROTAN1124.

[0034] The dry suspension of the present application embodiment is compounded with the traditional first wetting dispersant and the novel second wetting dispersant to enhance the synergy, which greatly improves the dispersing effect on the active ingredient and improves the dispersibility of the active ingredient in the dry suspension. When the dry suspension of the present application embodiment is dispersed in a solvent such as water to form a suspension, the active ingredient in the suspension has good dispersibility and a small particle size, even reaching the nanometer level. When these suspensions are applied by spraying, the active ingredient particles are attached to a large amount of leaves and other parts, and are easily absorbed by target pests or plants, and have the characteristics of high efficacy and low dosage.

[0035] The first wetting dispersant is a traditional wetting dispersant commonly used in the dry suspension concentrate in the industry; the second wetting dispersant is a new type of wetting dispersant that is not commonly used in the dry suspension concentrate in the industry. The compound use of the two types of dispersants effectively improves the dispersion effect. Among them, the sources of the first wetting dispersant and the wetting dispersant can be shown in the following Table 1:

[0036] Table 1

[0037]

[0038]

[0039] In some embodiments, the weight fraction of the first wetting and dispersing agent in the dry suspension of the present application can be 10 to 14.5 parts, and can be 10 to 14 parts, 11 to 15 parts, or 12 to 15 parts. In the exemplary embodiment, the weight fraction of the first wetting and dispersing agent in the dry suspension of the present application can be 10 parts, 10.5 parts, 11 parts, 11.5 parts, 12 parts, 12.5 parts, 13 parts, 13.5 parts, 14 parts, 14.5 parts, 15 parts, etc., which are typical but non-limiting weight fractions, or any weight fraction between any two numerical ranges. Controlling the weight fraction of the first wetting and dispersing agent within this range further promotes the synergistic effect of the compounding between the first wetting and dispersing agent and the second wetting and dispersing agent, improves the dispersion effect, and further improves the dispersibility of the active ingredient in the dry suspension of the present application.

[0040] In some embodiments, the weight fraction of the second wetting dispersant in the dry suspension of the present application can be 3 to 7.5 parts, which can be 3 to 7 parts, 3 to 6 parts, 4 to 8 parts, and 5 to 8 parts. In the exemplary embodiment, the weight fraction of the second wetting dispersant in the dry suspension of the present application can be 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts, 5.5 parts, 6 parts, 6.5 parts, 7 parts, 7.8 parts, 8 parts, etc., which are typical but non-limiting weight fractions, or any weight fraction between any two numerical ranges. Controlling the weight fraction of the second wetting dispersant within this range further promotes the compounding synergistic effect between the second wetting dispersant and the first wetting dispersant, improves the dispersing effect of the wetting dispersant on the active ingredient, reduces the particle size of the dry suspension of the present application embodiment after forming a suspension, and further improves the efficacy.

[0041] It should be noted that the first wetting and dispersing agent of the dry suspension agent of the embodiment of the present application may be only one, or two or more, and there is no specific limitation; the second wetting and dispersing agent may be only one, or two or more, and there is no specific limitation. For example, in an exemplary embodiment, the first wetting and dispersing agent in the dry suspension agent of the embodiment of the present application may include HDB-1904X and Morwet-D425 in a mass ratio of 3:10, and the second wetting and dispersing agent may include Hostaphat 1306; in another exemplary embodiment, the first wetting and dispersing agent in the dry suspension agent of the embodiment of the present application may include Morwet-EFW and Winst 3117MAX in a mass ratio of 2:10, and the second wetting and dispersing agent may include MF608 and MF605 in a mass ratio of 3:3.

[0042] In some embodiments, the weight proportion of the active ingredient in the dry suspension of the present application can be 30 to 80 parts, which can be selected as 25 to 75 parts, 30 to 75 parts, 40 to 80 parts, and 50 to 80 parts. In the exemplary embodiment, the weight proportion of the active ingredient in the dry suspension of the present application can be 25 parts, 28 parts, 30 parts, 32 parts, 35 parts, 38 parts, 40 parts, 42 parts, 45 parts, 48 ​​parts, 50 parts, 52 parts, 55 parts, 58 parts, 60 parts, 62 parts, 65 parts, 68 parts, 70 parts, 72 parts, 75 parts, 78 parts, 80 parts, etc., which are typical but non-limiting weight proportions, or any weight proportion between any two numerical ranges. Controlling the weight proportion of the active ingredient within this range further improves the dispersibility of the active ingredient in the dry suspension of the present application embodiment and improves the efficacy of the dry suspension of the present application embodiment.

[0043] In some embodiments, the active ingredient of the dry suspension of the present application embodiment may include at least one of spirotetramat and pymetrozine. The dispersibility of the active ingredient in the dry suspension is not only affected by the wetting and dispersing agent, but also by the physical and chemical properties of the active ingredient. When the active ingredient is spirotetramat and / or pymetrozine, spirotetramat and / or pymetrozine interact with the wetting and dispersing agent in the dry suspension, which can further improve the dispersibility and dispersion stability of the active ingredient in the dry suspension, and reduce the particle size of the suspension obtained by redispersing the dry suspension in water.

[0044] In some embodiments, when the active ingredients include spirotetramat and pymetrozine, the mass ratio of spirotetramat and pymetrozine can be (25-40): (25-40), optionally (25-40): (30-40), (25-40): (25-40), (25-40): (25-40). In the exemplary embodiment, the mass ratio of spirotetramat and pymetrozine can be a typical but non-limiting mass ratio such as 25:40, 25:35, 25:30, 25:25, 30:25, 35:25, 40:25, or any mass ratio between any two ratio ranges. Controlling the mass ratio of spirotetramat and pymetrozine further promotes the synergistic effect between the two active ingredients of spirotetramat and pymetrozine, and further improves the dispersibility and dispersion stability of the active ingredients in the dry suspension.

[0045] In some embodiments, the weight proportion of the active ingredient spirotetramat in the dry suspension of the present application can be 25 to 40 parts, optionally 25 to 35 parts, 28 to 40 parts, or 30 to 40 parts. In the exemplary embodiment, the weight proportion of the active ingredient spirotetramat can be 25 parts, 26 parts, 27 parts, 28 parts, 29 parts, 30 parts, 31 parts, 32 parts, 33 parts, 34 parts, 35 parts, 36 parts, 37 parts, 38 parts, 39 parts, 40 parts, etc., which are typical but non-limiting weight proportions, or any weight proportion between any two numerical ranges.

[0046] In some embodiments, the weight proportion of the active ingredient pymetrozine in the dry suspension of the present application can be 25 to 40 parts, optionally 25 to 35 parts, 28 to 40 parts, or 30 to 40 parts. In the exemplary embodiment, the weight proportion of the active ingredient pymetrozine can be 25 parts, 26 parts, 27 parts, 28 parts, 29 parts, 30 parts, 31 parts, 32 parts, 33 parts, 34 parts, 35 parts, 36 parts, 37 parts, 38 parts, 39 parts, 40 parts, etc., which are typical but non-limiting weight proportions, or any weight proportion between any two numerical ranges.

[0047] By controlling the weight proportions of spirotetramat and pymetrozine within the range, the content of the active ingredient in the dry suspension is increased on the basis of promoting the synergistic effect between the two active ingredients of spirotetramat and pymetrozine, and the dispersibility of the active ingredient in the dry suspension is further improved, so that the efficacy of the dry suspension is further improved when the mass of the dry suspension is the same.

[0048] In some embodiments, the dry suspension of the present application may further include a filler. The addition of the filler can effectively fill the gaps between the active ingredient particles of the dry suspension of the present application, stabilize the dispersion state of the active ingredient particles, reduce the aggregation between the active ingredient particles, and reduce the occurrence of agglomeration and active ingredient precipitation.

[0049] In some embodiments, the filler may include at least one of barium sulfate and sodium sulfate. These fillers have good stability and a high relative area, and have good hydrophilicity, and can not only stabilize the dispersion state of the active ingredient particles, but also promote the dry suspension to be quickly wetted by water when the dry suspension of the embodiment of the present application is redispersed in water to form a suspension, thereby further promoting the redispersion of the dry suspension in water and improving the dispersibility of the dry suspension in water.

[0050] In some embodiments, when the dry suspension of the present application contains fillers, the weight percentage of the fillers can be 10 to 60 parts, and can be selected as 10 to 30 parts, 10 to 50 parts, and 30 to 60 parts. In the exemplary embodiment, the weight percentage of the fillers in the dry suspension of the present application can be 10 parts, 11 parts, 12 parts, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 25 parts, 30 parts, 35 parts, 40 parts, 45 parts, 50 parts, 55 parts, 60 parts, etc. Typical but non-limiting weight percentages. Controlling the weight percentage of the fillers in the dry suspension of the present application within this range further improves the dispersion stability of the active ingredient particles in the dry suspension, improves the dispersibility of the dry suspension in water, and at the same time increases the content of the active ingredient in the dry suspension, and improves the efficacy of the dry suspension.

[0051] In some embodiments, the dry suspension of the present application may further include an acid-base regulator. In the exemplary embodiment, the acid-base regulator may include at least one of citric acid, lactic acid, phosphoric acid, and acetic acid. The addition of these acid-base regulators can effectively adjust the pH value of the dry suspension of the present application, improve the dispersibility and stability of the dry suspension itself, and improve the dispersibility and stability of the suspension obtained by dispersing the dry suspension in water, thereby improving the efficacy of the dry suspension.

[0052] In some embodiments, when the dry suspension of the present application contains an acid-base regulator, the weight portion of the acid-base regulator can be 0.3 to 1 part, and can be selected as 0.3 to 0.9 parts, 0.3 to 0.8 parts, 0.4 to 1 parts, 0.5 to 1 parts, and 0.5 to 0.8 parts. In the exemplary embodiment, the weight portion of the acid-base regulator in the dry suspension of the present application can be 0.3 parts, 0.4 parts, 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, 0.9 parts, 1 parts, etc., which are typical but non-limiting weight portions, or any weight portion between any two numerical ranges. The weight portion of the acid-base regulator is controlled within this range, and the pH of the dry suspension is adjusted within an appropriate range, so as to further improve the dispersibility and stability of the active components of the pesticide, and improve the utilization and efficacy of the active ingredients.

[0053] In some embodiments, the dry suspension of the present application may further include a defoamer. In the exemplary embodiment, the defoamer may include at least one of organosiloxane, tributyl phosphate, trioctyl phosphate, saturated aliphatic carboxylic acid ester, and alkyl ether phosphate. The addition of these defoamers can effectively reduce the foam generated during the preparation of the dry suspension of the present application, improve production efficiency and product yield, and can also reduce the foam generated in the suspension prepared by dispersing the dry suspension of the present application in water when used, further improve the dispersibility of the active ingredients in the suspension, improve the spraying effect of the suspension, and improve the efficacy.

[0054] In some embodiments, when the dry suspension of the present application contains a defoamer, the weight portion of the defoamer can be 1 to 2 parts, which can be selected from 1 to 1.8 parts, 1 to 1.5 parts, 1.2 to 2 parts, and 1.5 to 2 parts. In the exemplary embodiment, the weight portion of the defoamer in the dry suspension of the present application can be 1 part, 1.1 parts, 1.2 parts, 1.3 parts, 1.4 parts, 1.5 parts, 1.6 parts, 1.7 parts, 1.8 parts, 1.9 parts, 2 parts, etc., which are typical but non-limiting weight portions, or any weight portion between any two numerical ranges. Controlling the weight portion of the defoamer in the dry suspension of the present application embodiment within this range further reduces the foam generated during the preparation of the dry suspension of the present application embodiment, as well as the foam in the suspension prepared by dispersing in water, further improves the spraying effect of the suspension, and improves the efficacy.

[0055] In some embodiments, the moisture content of the dry suspension of the present application can be ≤3%, and can be selected as 1% to 3%. In the exemplary embodiment, the moisture content of the dry suspension can be 1%, 1.2%, 1.5%, 1.6%, 1.7%, 1.8%, 1.9%, 2%, 2.1%, 2.2%, 2.3%, 2.4%, 2.5%, 2.6%, 2.7%, 2.8%, 2.9%, 3%, etc., which are typical but non-limiting values. Controlling the moisture content of the dry suspension of the present application embodiment within this range can reduce the occurrence of agglomeration of the dry suspension of the present application embodiment, and further improve the storage stability of the dry suspension.

[0056] In some embodiments, the particle size of the dry suspension of the present invention can be 120 mesh to 20 mesh. Controlling the particle size of the dry suspension of the present invention within this range further improves the stability of the dry suspension and prolongs the shelf life of the dry suspension.

[0057] In some embodiments, when the dry suspension agent of the present application is dispersed in water to form a suspension, the particle size D90 of the particles in the suspension can be 400-700 nm, optionally 400-600 nm, 500-700 nm. The suspension can be a suspension formed by dispersing 1 g of the dry suspension agent in 50 g of water. In the exemplary embodiment, when the dry suspension of the present application is dispersed in water to form a suspension, the particle size D90 of the suspension can be 400nm, 410nm, 420nm, 430nm, 440nm, 450nm, 460nm, 470nm, 480nm, 490nm, 500nm, 510nm, 520nm, 530nm, 540nm, 550nm, 560nm, 570nm, 580nm, 590nm, 600nm, 610nm, 620nm, 630nm, 640nm, 650nm, 670nm, 680nm, 690nm, 700nm and other typical but non-limiting sizes, or any size between any two numerical ranges. Controlling the particle size of the particles in the suspension made from the dry suspension of the present application embodiment within this range further promotes the performance of the efficacy of the active ingredients in the dry suspension and improves the efficacy of the dry suspension.

[0058] In a second aspect, the present invention provides a method for preparing the above-mentioned dry suspension concentrate. The method for preparing the dry suspension concentrate in the present invention comprises the following steps:

[0059] Step S10: mixing and grinding the active ingredient, the first wetting and dispersing agent, the second wetting and dispersing agent and the solvent to obtain a mixed slurry;

[0060] Step S20: drying the mixed slurry to obtain a dry suspension.

[0061] The active ingredient, the first wetting and dispersing agent, the second wetting and dispersing agent and the dry suspending agent are the active ingredient, the first wetting and dispersing agent, the second wetting and dispersing agent and the dry suspending agent mentioned above, and will not be described in detail here.

[0062] The dry suspension preparation method of the embodiment of the present application mixes and grinds two types of dispersants, the first wetting dispersant and the second wetting dispersant, with the active ingredient and the solvent, and controls the weight proportions of the first wetting dispersant, the second wetting dispersant and the active ingredient within a specific range, effectively improving the dispersibility of the active ingredient, making the particle size in the obtained mixed slurry small, which can reach the nanometer level, thereby effectively improving the dispersibility of the active component in the dry suspension obtained after drying, and improving the efficacy of the dry suspension. In addition, the dry suspension preparation method of the embodiment of the present application has fewer process steps, less dust pollution, easy-to-control process conditions, high production efficiency, and is suitable for large-scale industrial production.

[0063] Step S10:

[0064] In step S10, the active ingredient, the first wetting and dispersing agent, the second wetting and dispersing agent, and the solvent are mixed so that the materials are mixed with each other, and then ground to disperse the active ingredient to obtain a mixed slurry with a small particle size.

[0065] In some embodiments, the solvent may include water. The preparation of the mixed slurry with a solvent including water further improves the dispersibility of the active ingredient. At the same time, when the dry suspension of the present application embodiment is used, water is usually used to redisperse it to form a suspension, and water is used as a solvent to prepare the mixed slurry, which effectively reduces the difference between the particle size in the mixed slurry and the particle size in the suspension during use, thereby improving the quality control level of the product. In addition, using water as a solvent can effectively reduce the volatilization of organic solvents in the subsequent drying process, which is beneficial to reducing production costs and environmental protection.

[0066] In some embodiments, the water content in the mixed slurry can be 30% to 60%, optionally 45% to 60%, 50% to 60%. In the exemplary embodiment, the water content in the mixed slurry can be 30%, 35%, 40%, 45%, 50%, 55%, 60% and other typical but non-limiting values, or any value between any two numerical ranges. Controlling the water content in the mixed slurry within this range further promotes the mixing and dispersion of materials, improves the rheological properties of the mixed slurry, further reduces the particle size of particles in the mixed slurry, improves the dispersion stability of the mixed slurry, and reduces the difficulty of the subsequent drying process, thereby improving the stability of the quality of the dry suspension product.

[0067] In some embodiments, at least one of an acid-base regulator, a defoamer and a filler is also added during the mixing process. The addition of these additives can further improve the dispersibility and dispersion stability of the active components in the mixed slurry, while reducing the generation of foam during the mixing process, grinding process, etc., improving production efficiency, and improving the quality of the dry suspension. When acid-base regulators, defoamers, fillers and other additives are added during the mixing process, the weight portion of the acid-base regulator can be 0.3 to 1 part, the weight portion of the defoamer can be 1 to 2 parts, and the weight portion of the filler can be 10 to 60 parts. These acid-base regulators, defoamers and fillers are the acid-base regulators, defoamers and fillers mentioned above, and will not be repeated here.

[0068] In some embodiments, a high-speed shearing machine can be used for mixing to further promote the mixing of materials. In a further embodiment, the mixing process using a high-speed shearing machine can be carried out at a speed of 1500 to 2000 revolutions per minute for 30 minutes.

[0069] In some embodiments, grinding can be performed in a horizontal sand mill to promote the dispersion of active ingredients in the mixed slurry. In further embodiments, grinding can be performed in a horizontal sand mill until no large particles exist in the mixed slurry, for example, the particle size of the particles in the mixed slurry is less than 5 microns, and can also be less than 3 μm, without specific limitation.

[0070] In some embodiments, after the grinding process, the mixed slurry can also be screened. In an exemplary embodiment, a 120-mesh screen can be used to screen the mixed slurry. The screening process effectively removes the foamed rice and oversized particles in the mixed slurry, further improving the uniformity of the mixed slurry.

[0071] In some embodiments, a high-pressure homogenizer may be used to homogenize the mixed slurry before drying. In the exemplary embodiment, the pressure of the homogenization process may be 500-800 MPa, optionally 500-600 MPa, 500-650 MPa; the flow rate may be 20-30 L / min, 20-25 L / min, 22-30 L / min; and the time may be 30-40 min. In the exemplary embodiment, the pressure of the homogenization process can be 500Mpa, 510Mpa, 520Mpa, 530Mpa, 540Mpa, 550Mpa, 560Mpa, 570Mpa, 580Mpa, 590Mpa, 600Mpa, 610Mpa, 620Mpa, 630Mpa, 640Mpa, 650Mpa, 660Mpa, 670Mpa, 680Mpa, 690Mpa, 700Mpa, 750Mpa, 800Mpa, etc., or any typical but non-limiting size. Any size between two numerical ranges; the flow rate of homogenization treatment can be 20L / min, 21L / min, 22L / min, 23L / min, 24L / min, 25L / min, 26L / min, 27L / min, 28L / min, 29L / min, 30L / min and other typical but non-limiting sizes, or any size between any two numerical ranges; the time of homogenization treatment can be 20min, 25min, 30min and other typical but non-limiting times, or any time between any two numerical ranges. Homogenizing the mixed slurry with a high-pressure homogenizer can further promote the dispersion of the active components, reduce the particle size of the particles in the mixed slurry, improve the dispersibility of the active components in the prepared dry suspension, and improve the efficacy of the dry suspension.

[0072] In some embodiments, the particle size D90 of the mixed slurry in the above embodiments can be 400-700nm; optionally 400-600nm, 400-550nm, 500-700nm. In the exemplary embodiment, the particle size D90 of the particles in the mixed slurry can be 400nm, 410nm, 420nm, 430nm, 440nm, 450nm, 460nm, 470nm, 480nm, 490nm, 500nm, 510nm, 520nm, 530nm, 540nm, 550nm, 560nm, 570nm, 580nm, 590nm, 600nm, 610nm, 620nm, 630nm, 640nm, 650nm, 660nm, 670nm, 680nm, 690nm, 700nm and other typical but non-limiting sizes, or any size between any two numerical ranges. Controlling the particle size of the particles in the mixed slurry within this range further promotes the dispersion of the active ingredients, improves the dispersibility of the active ingredients in the prepared dry suspension, and improves the efficacy of the dry suspension.

[0073] Step S20:

[0074] The mixed slurry is dried in step S20 to volatilize the solvent in the mixed slurry to obtain a dry suspension.

[0075] In some embodiments, the drying process may be spray drying, which effectively promotes the volatilization of the solvent in the mixed slurry and allows the good dispersibility of the active components in the mixed slurry to be well maintained in the dried material, thereby obtaining a dry suspension with a high degree of dispersion of the active components.

[0076] In some embodiments, the spray pressure in the spray drying process can be 4-6MPa, the air inlet temperature can be 130-150°C, and the air outlet temperature can be 55-75°C. In the exemplary embodiment, the spray pressure can be 4MPa, 4.5MPa, 5MPa, 5.5MPa, 6MPa, etc., which are typical but non-limiting values, or any value between two numerical ranges; the air inlet temperature can be 130°C, 135°C, 140°C, 145°C, 150°C, etc., which are typical but non-limiting values, or any value between two numerical ranges; the air outlet temperature can be 55°C, 60°C, 65°C, 70°C, 75°C, etc., which are typical but non-limiting values, or any value between two numerical ranges. Controlling the spray pressure, air inlet temperature, and air outlet temperature of the spray drying process within this range effectively maintains the dispersibility of the active component while promoting the full volatilization of the solvent, reduces the decomposition and volatilization of the active component, and further improves the quality and yield of the obtained dry suspension.

[0077] In some embodiments, after the spray drying process, the material can also be screened. In an exemplary embodiment, the material can be screened using a screener to obtain a dry suspension with a particle size of 120 mesh to 20 mesh. The screening process effectively removes lumps in the material, reduces powder in the material, and improves the particle uniformity of the dry suspension.

[0078] In a third aspect, the embodiments of the present application provide the use of the dry suspension concentrate described above in the control of crop diseases and insect pests.

[0079] The dry suspension concentrate of the present application has good dispersibility of the active components of the pesticide, and the particle size of the particles dispersed in a solvent such as water in the suspension is small. After the suspension is applied, the amount of active ingredients attached to the target pests and plant surfaces is large, so that the dry suspension concentrate of the present application has a good effect on the prevention and control of crop diseases and insect pests.

[0080] In some embodiments, the crop pest control includes at least one of wheat aphid control and tomato whitefly control. When the active ingredient includes spirotetramat and / or pymetrozine, the active ingredient has a good control effect on wheat aphids and tomato whiteflies. The dry suspension concentrate of the present application improves the dispersibility of the active ingredient, thereby further improving the control effect of the active ingredient on wheat aphids and tomato whiteflies.

[0081] In some embodiments, the amount of the dry suspension agent in the present application can be 90 to 112.5 g ai·hm -2 (active ingredient, g / hectare).

[0082] In some embodiments, when the dry suspension agent of the embodiment of the present application is used, 20 to 40 g of the dry suspension agent can be dispersed in 0.5 to 1.0 L of water to form a suspension for spraying. In the exemplary embodiment, when the dry suspension agent of the embodiment of the present application is used, 20 g, 25 g, 30 g, 35 g, 40 g of typical but non-limiting weights, or any weight of dry suspension agent between any two numerical ranges can be dispersed in 0.5 to 1.0 L of water to form a suspension for spraying. In further embodiments, the spraying method can be low-volume spraying and / or ultra-low-volume spraying to further improve the utilization rate of the dry suspension agent and improve the control effect of the dry suspension agent on crop diseases and pests.

[0083] In order to enable the above implementation details and operations of the present application to be clearly understood by those skilled in the art, and to demonstrate the significant improvement in performance of the dry suspension concentrate of the present application embodiment and its preparation method and application, the above technical solution is illustrated by multiple embodiments below.

[0084] 1. Dry suspension and its preparation method

[0085] Example 1

[0086] The present embodiment provides a dry suspension, and the dry suspension of the present embodiment is a 65% spirotetramat·pymetrozine nano dry suspension. The dry suspension of the present embodiment includes active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, an acid-base regulator, a defoamer, and a filler. Among them, the content of the active ingredients spirotetramat and pymetrozine is shown in Table 2; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the acid-base regulator, the defoamer, and the filler are shown in Table 2.

[0087] Table 2

[0088]

[0089] Note: The solid content of the frosting is 50%.

[0090] The method for preparing the dry suspension concentrate of this embodiment comprises the following steps:

[0091] Step S1: 100 kg of water is added to a 200 kg stirring kettle, and the weights of acid-base regulator citric acid, first wetting and dispersing agent HDB-1904x and Morwet-D425 and second wetting and dispersing agent Hostaphat 1306 are added in sequence, and stirred for 5 to 10 minutes. Then, the weights of active ingredients spirotetramat and pymetrozine, defoaming agent organosiloxane and filler anhydrous barium sulfate are added in sequence, and the mixture is mixed for 30 minutes by a high-speed shearing machine at 2000 rpm to prepare a premixed slurry after being mixed evenly.

[0092] Step S2: Add the premixed slurry in step S1 into a horizontal sand mill and sand grind for 60 minutes, using 0.4-0.6 mm beads as the grinding medium, until the particle size is less than 5 microns to obtain a mixed slurry.

[0093] Step S3: filtering the mixed slurry in step S2 using 120-mesh gauze to obtain a filtered mixed slurry.

[0094] Step S4: Add the mixed slurry filtered in step S3 into a high-pressure homogenizer for homogenization. The homogenization pressure is 500 MPa, the flow rate is 30 L / min, the temperature is 30°C, and the speed is 3000 rpm. The particle size of the mixed slurry is controlled to be nanometer level.

[0095] Step S5: The mixed slurry that has been homogenized in step S4 is pumped into a centrifugal spray dryer for drying and granulation. The spray pressure of the spray drying tower is controlled at 4 MPa, the inlet air temperature is controlled at 145° C., and the outlet air temperature is controlled at 70° C. The moisture content of the particles obtained after spray drying is less than 3%, and the particles obtained after drying are sieved using a material sieving machine to obtain particles with a particle size of 120 mesh to 20 mesh, which are the dry suspension agent of this embodiment.

[0096] Example 2

[0097] The present embodiment provides a dry suspension, which is a 65% spirotetramat·pymetrozine nano dry suspension. The dry suspension of the present embodiment includes active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, an acid-base regulator, a defoamer and a filler. Among them, the active ingredients are spirotetramat and pymetrozine in the content as shown in Table 3; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the acid-base regulator, the defoamer and the filler are shown in Table 3.

[0098] The preparation method of the dry suspension concentrate of this embodiment is substantially the same as the preparation method of the dry suspension concentrate of embodiment 1.

[0099] Table 3

[0100]

[0101] Note: The solid content of the frosting is 50%.

[0102] Example 3

[0103] The present embodiment provides a dry suspension, and the dry suspension of the present embodiment is a 65% spirotetramat·pymetrozine nano dry suspension. The dry suspension of the present embodiment includes active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, an acid-base regulator, a defoamer and a filler. Among them, the active ingredients are spirotetramat and pymetrozine in the content as shown in Table 4; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the acid-base regulator, the defoamer and the filler are shown in Table 4.

[0104] The preparation method of the dry suspension concentrate of this embodiment is substantially the same as the preparation method of the dry suspension concentrate of embodiment 1.

[0105] Table 4

[0106]

[0107]

[0108] Note: The solid content of the frosting is 50%.

[0109] Example 4

[0110] The present embodiment provides a dry suspension, which is a 65% spirotetramat·pymetrozine nano dry suspension. The dry suspension of the present embodiment includes active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, an acid-base regulator, a defoamer and a filler. Among them, the active ingredients are spirotetramat and pymetrozine in the content as shown in Table 5; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the acid-base regulator, the defoamer and the filler are shown in Table 5.

[0111] The preparation method of the dry suspension concentrate of this embodiment is substantially the same as the preparation method of the dry suspension concentrate of embodiment 1.

[0112] Table 5

[0113]

[0114] Note: The solid content of the frosting is 50%.

[0115] Example 5

[0116] The present embodiment provides a dry suspension, and the dry suspension of the present embodiment is a 65% spirotetramat·pymetrozine nano dry suspension. The dry suspension of the present embodiment includes active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, an acid-base regulator, a defoamer and a filler. Among them, the active ingredients are spirotetramat and pymetrozine in the content as shown in Table 6; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the acid-base regulator, the defoamer and the filler are shown in Table 6.

[0117] The preparation method of the dry suspension concentrate of this embodiment is substantially the same as the preparation method of the dry suspension concentrate of embodiment 1.

[0118] Table 6

[0119]

[0120] Note: The solid content of the frosting is 50%.

[0121] Example 6

[0122] The present embodiment provides a dry suspension, and the dry suspension of the present embodiment is a 65% spirotetramat·pymetrozine nano dry suspension. The dry suspension of the present embodiment comprises active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, an acid-base regulator, a defoamer and a filler. Among them, the content of the active ingredients spirotetramat and pymetrozine is shown in Table 7; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the acid-base regulator, the defoamer and the filler are shown in Table 7.

[0123] The preparation method of the dry suspension concentrate of this embodiment is substantially the same as the preparation method of the dry suspension concentrate of embodiment 1.

[0124] Table 7

[0125]

[0126] Note: The solid content of the frosting is 50%.

[0127] Comparative Example 1

[0128] This comparative example provides a dry suspension, which is a 65% spirotetramat·pymetrozine nano dry suspension. The dry suspension in this comparative example includes active ingredients spirotetramat and pymetrozine, a first wetting and dispersing agent, a second wetting and dispersing agent, an acid-base regulator, a defoamer and a filler. Among them, the active ingredients are spirotetramat and pymetrozine in the content as shown in Table 8; the types and contents of the first wetting and dispersing agent, the second wetting and dispersing agent, the acid-base regulator, the defoamer and the filler are shown in Table 8.

[0129] The preparation method of the dry suspension concentrate of this comparative example is basically the same as the preparation method of the dry suspension concentrate of Example 1.

[0130] Table 8

[0131]

[0132] Note: The solid content of the frosting is 50%.

[0133] Compared with Example 6, the difference of Comparative Example 1 is that the second wetting and dispersing agents OROTAN 731A and OROTAN 1124 in the dry suspension concentrate of Example 6 are replaced by the first wetting powder GY-D800.

[0134] Comparative Example 2

[0135] This comparative example provides a dry suspension concentrate, which is a 65% spirotetramat·pymetrozine nano dry suspension concentrate. The components of the dry suspension concentrate in this comparative example are the same as those of the dry suspension concentrate in comparative example 1.

[0136] The preparation method of the dry suspension concentrate of this comparative example is substantially the same as the preparation method of the dry suspension concentrate of comparative example 1, except that: the high-pressure homogenizer is not used for high-pressure homogenization during the preparation of the dry suspension concentrate of this comparative example.

[0137] 2. Investigation of physical and chemical properties:

[0138] 2.1. Investigation of mixed slurry and finished product particle size

[0139] The mixed slurries of different sand grinding times in the preparation process of the dry suspension concentrates of the above Examples 1-6 and Comparative Examples 1-2, and the mixed slurries after homogenization were taken, and their particle sizes were measured. The results are shown in Table 9. Another appropriate amount of the dry suspension concentrates obtained after spray drying of the above Examples 1-6 and Comparative Examples 1-2 was taken and dispersed in an appropriate amount of water at a ratio of dry suspension concentrate: water = 1:50 to form a suspension, and the particle size in the suspension was measured. The results are shown in Table 9.

[0140] Table 9

[0141]

[0142]

[0143] As shown in Table 9, compared with Comparative Examples 1 and 2 which use only one wetting dispersant, the grinding efficiency of the mixed slurry is more than doubled by compounding the first wetting dispersant and the second wetting dispersant at the same time. For the same grinding time, the particle size D90 of the mixed slurries of Examples 1 to 6 in which the two wetting dispersants are mixed is approximately about half of the particle size of the mixed slurries of Comparative Examples 1 and 2 which use only the first wetting dispersant.

[0144] After homogenization by a high-pressure homogenizer, the particle size of the mixed slurry is further reduced to about 500 nm, which indicates that the particle size of the mixed slurry in the preparation of the dry suspension concentrate in the embodiment of the present application can be further reduced by homogenization by a high-pressure homogenizer.

[0145] In addition, the mixed slurry is spray-dried to obtain a dry suspension, and the dry suspension is redispersed in water to obtain a suspension. Compared with the mixed slurry, the particle size of the particles in the suspension is not significantly increased, which indicates that the active ingredient particles and the auxiliary agent in the dry suspension of the embodiment of the present application are tightly combined, and no obvious shedding occurs in a high temperature environment. The quality of the produced dry suspension is stable and meets the actual application requirements.

[0146] 2.2. Preparation performance investigation

[0147] The dry suspensions of Examples 1 to 6 and Comparative Example 1 were subjected to stability tests. The stability test items included a room temperature storage test and a hot storage test, wherein the room temperature storage test condition was storage at 25°C for 14 days, and the hot storage test condition was storage at 54°C for 14 days. The appearance, content change (i.e., the decomposition rate of the active ingredient), suspension rate (GB / T 14825-2006), dispersibility (GB / T 32775-2016), and persistent foaming (GB / T28137-2011) of the dry suspensions after storage were investigated, and the results are shown in Table 10, which is the test results after 14 days of hot storage.

[0148] Table 10

[0149]

[0150]

[0151] Note: The "decomposition rate" in Table 10 represents the difference between the content of the active ingredient after 14 days of storage at room temperature and the content of the active ingredient after 14 days of hot storage. The decomposition rate should be less than or equal to 3%, wherein, decomposition rate (%) = (content after 14 days of storage at room temperature - content after 14 days of hot storage) / content after 14 days of storage at room temperature × 100%.

[0152] As shown in Table 10, after the dry suspension concentrates of Examples 1 to 6 of the present application were stored at room temperature for 14 days and hot stored for 14 days, the dry suspension concentrates had uniform appearance, less foam, good dispersibility, high suspension rate of active ingredients and low decomposition rate of active ingredients, indicating that the dry suspension concentrates provided by the examples of the present application have good stability and are easy to store and transport.

[0153] 2.3. Particle size study of dry suspension preparations

[0154] The dry suspension concentrates of Examples 1 to 6 and Comparative Example 1 were respectively taken, and the particle sizes after being dispersed in water were measured, and the results are shown in Table 10. The dry suspension concentrates of Examples 1 to 6 and Comparative Example 1 were stored at room temperature and hot storage, and the samples after storage were dispersed in water, and the particle sizes were measured, and the results are shown in Table 11. The room temperature storage test condition was storage at 25°C for 14 days, and the hot storage test condition was storage at 54°C for 14 days.

[0155] Table 11

[0156]

[0157] As shown in Table 11, the dry suspensions of Examples 1 to 6 were redispersed in water to prepare suspensions, and the particle size in the suspensions reached the nanometer level, about 500 nm, and after 14 days of storage at room temperature and 14 days of heat storage, the particle size did not change significantly, and was still about 500 nm. However, after the dry suspension of Comparative Example 1 was redispersed to prepare a suspension, the particle size of the particles in the suspension was greater than 2.5 μm. This shows that the dry suspension provided by the embodiment of the present application is compounded with the first wetting dispersant and the second wetting dispersant, not only greatly improving the grinding efficiency during the preparation of the dry suspension, but also greatly improving the dispersibility of the active ingredient in the dry suspension. For example, in the same grinding time, the particle size of the dry suspension of Examples 1-6 is only about one-fifth of that of the comparative example. At the same time, the particle size of the suspension of the samples of Examples 1-6 stored hot for 14 days did not change significantly, indicating that the dispersion stability of the active ingredient in the dry suspension of the embodiment of the present application is further improved by compounding the first wetting dispersant and the second wetting dispersant.

[0158] 3. Field efficacy study - wheat aphids

[0159] Chemical treatment:

[0160] Treatments 1-7: dry suspensions of Examples 1 to 6 and Comparative Example 1; Treatment 8 (control agent): 75% spirotetramat·pymetrozine (wherein the ratio of spirotetramat to pymetrozine is spirotetramat:pymetrozine=20:55, Shaanxi Shanggezhilu Biological Science Co., Ltd.).

[0161] Test subject: wheat aphid

[0162] Test method: Refer to the Field Efficacy Test Guidelines (II) Pesticide Control of Wheat Aphids (GB / T17980,79-2000), set 10m 2 The plots were separated by protective rows, with 3 replicates for each treatment and a blank control area for drug administration.

[0163] Trial time: May 10, 2023 - May 24, 2023.

[0164] Experimental location: Shangjiang Village, Anjiazhuang Town, Feicheng City, Tai'an City, Shandong Province.

[0165] Field survey and statistical analysis: Aphids were surveyed in the plots 1, 3, 7, and 14 days after application. Five sampling points were taken in each plot. 5 to 10 plants with aphids were fixed at each point. The number of aphids on the fixed plants was surveyed and the control effect was calculated. The calculation formula is shown in the following formula (1):

[0166]

[0167] The particle size of each treatment at the time of application and the aphid control effect are shown in Table 12:

[0168] Table 12

[0169]

[0170]

[0171] As shown in Table 12, the dry suspension concentrates of Examples 1 to 6 have smaller particle sizes than the dry suspension concentrates of the comparative example and the dry suspension concentrates sold on the market, and the dry suspension concentrates of Examples 1 to 6 have better control effects on controlling wheat aphids than the dry suspension concentrates of the comparative example and the dry suspension concentrates sold on the market.

[0172] Among them, the 14-day control effect of the dry suspension concentrate of Example 1 was the highest, which was 87.05%, 18.93% higher than the control effect of 70.12% of the control agent; the dry suspension concentrates of Example 6 and Comparative Example 1 had basically the same composition, except that the dry suspension concentrate of Comparative Example 1 did not contain the second wetting and dispersing agent, and the control effect of the dry suspension concentrate of Example 6 on wheat aphids was significantly higher than that of the dry suspension concentrate of Comparative Example 1. This shows that when the total amount of active ingredients of the pesticide applied is the same, the dry suspension concentrate provided in the examples of the present application effectively improves the efficacy of the active ingredients.

[0173] 3. Field efficacy study - Tomato whitefly

[0174] Chemical treatment:

[0175] Treatments 1-7: dry suspensions of Examples 1 to 6 and Comparative Example 1; Treatment 8 (control agent): 40% spirotetramat suspension (Guangxi Tianyuan Biochemical Co., Ltd.).

[0176] Test subject: Tomato whitefly.

[0177] Test method: Refer to the Pesticide Field Efficacy Test Standard Part 43: Insecticides for Control of Vegetable Whiteflies (NY / T1464.43-2012), set 15m for each treatment. 2 The plots were separated by protective rows, with 4 replicates and a blank control area.

[0178] Trial time: July 10, 2023 - July 24, 2023.

[0179] Experimental location: Nanwushan Village, Jiaxiang County, Jining City, Shandong Province.

[0180] Field survey and statistical analysis: 10 plants were marked in each plot. The number of adults on the whole plant was investigated in the morning before application when the adults were inactive. The number of live adults in the plot was investigated 1 day, 3 days, 7 days, and 14 days after application, and the control effect was calculated. The calculation formula is shown in the above formula (1):

[0181] The particle size of each treatment at the time of application and the aphid control effect are shown in Table 13:

[0182] Table 13

[0183]

[0184] As shown in Table 13, compared with the dry suspension concentrate of Comparative Example 1 and the control agent, the dry suspension concentrates of Examples 1 to 6 have better effects in controlling tomato whiteflies. This shows that the dry suspension concentrates provided in the examples of the present application effectively improve the efficacy of the pesticide under the condition of the same pesticide dosage.

[0185] The above description is only a preferred embodiment of the present application and is not intended to limit the present application. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present application should be included in the protection scope of the present application.

Claims

1. A dry suspension concentrate, characterized in that: The composition comprises the following components in parts by weight: Active ingredient 25-80 parts 10-15 parts of the first wetting and dispersing agent 3 to 8 parts of the second wetting and dispersing agent; Wherein, the first wetting and dispersing agent includes at least one of sodium dodecylbenzene sulfonate, HDB-1904x, HDB-1903, MorwetEFW, Morwet IP, Petro AA, 207k, DS6008, Morwet D425, Agrilan 700, Winst 3117, Winst3118, SP-DF2238, SP-DF2258, and GY-D800; The second wetting and dispersing agent includes at least one of F608, MF605, Hostaphat 1306, AA4145, OROTAN731A, OROTAN963, and OROTAN1124.

2. The dry suspension concentrate according to claim 1, wherein The active ingredient includes at least one of spirotetramat and pymetrozine.

3. The dry suspension concentrate as claimed in claim 2, characterized in that The weight proportion of spirotetramat is 25 to 40 parts; and / or The weight proportion of the pymetrozine is 25 to 40 parts.

4. The dry suspension concentrate according to any one of claims 1 to 3, characterized in that The dry suspension agent further comprises at least one of an acid-base regulator, a defoamer, and a filler, and the weight proportion of the at least one of the acid-base regulator, the defoamer, and the filler in the dry suspension agent is as follows: 0.3 to 1 part of the acid-base regulator 1 to 2 parts of the defoamer The filler is 10 to 60 parts.

5. The dry suspension concentrate as claimed in claim 4, characterized in that The acid-base regulator comprises at least one of citric acid, lactic acid, phosphoric acid and acetic acid; and / or The defoaming agent comprises at least one of organic siloxane, tributyl phosphate, trioctyl phosphate, saturated aliphatic carboxylic acid ester, and alkyl ether phosphate; and / or The filler includes at least one of barium sulfate and sodium sulfate.

6. The dry suspension according to any one of claims 1 to 3 and 5, characterized in that: The water content of the dry suspension is ≤ 3%; and / or The particle size of the dry suspension is greater than or equal to 120 mesh and less than or equal to 20 mesh; and / or The dry suspending agent is dispersed in water to prepare a suspension, and the particle size of the particles in the suspension is 400-700nm.

7. The method for preparing a dry suspension according to any one of claims 1 to 3, characterized in that: The steps include: The active ingredient, the first wetting and dispersing agent, the second wetting and dispersing agent and the solvent are mixed and ground to obtain a mixed slurry; The mixed slurry is dried to obtain a dry suspension.

8. The preparation method according to claim 7, characterized in that: Before drying the mixed slurry, the slurry is further homogenized; and / or The mass content of water in the mixed slurry is 30-60%; and / or The particle size of the particles in the mixed slurry is 400-700 nm; and / or The mixing treatment further includes adding at least one of an acid-base regulator, a defoamer, and a filler, and the weight proportion of the at least one of the acid-base regulator, the defoamer, and the filler in the dry suspension is as follows: 0.3 to 1 part of the acid-base regulator 1 to 2 parts of the defoamer 10 to 60 parts of the filler; and / or The drying treatment method is spray drying, and the conditions of the spray drying include the following: the spray pressure is 4-6MPa, the air inlet temperature is 130-150°C, and the air outlet temperature is 55-75°C.

9. Use of the dry suspension concentrate according to any one of claims 1 to 6 or the dry suspension concentrate prepared by the preparation method according to any one of claims 7 to 8 in controlling crop diseases and insect pests.

10. The use according to claim 9, characterized in that The crop pest control includes at least one of wheat aphid control and tomato whitefly control; and / or The dosage of the dry suspension is 90-112.5 g ai·hm -2 ; and / or The method for using the dry suspension comprises: dispersing 20 to 40 g of the dry suspension in 0.5 to 1.0 L of water to prepare a suspension, and performing spraying treatment.

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