Preparation method and application of pH response type tannic acid modified pyraclostrobin metal organic framework nanocomposite
By modifying tannin on the metal organic framework nanocomposite of pyramidine, a pH-responsive nanocomposite was formed, which solved the problem of photolysis of pyramidine and short effective period, and achieved the improvement of its slow-release and antifungal activity.
CN119655263APending Publication Date: 2025-03-21GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY
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Patent Information
- Application Number
- CN202411846102.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-16
- Publication Date
- 2025-03-21
AI Technical Summary
Technical Problem
During the application of pyrazolestrobin in the field, there are shortcomings such as photolysis and short validity period, which seriously restricts its efficient use in disease prevention and control.
Method used
The preparation method of pyrazolestrobin metal organic framework nanocomposite (Pyr-ZIF-8-TA) modified with pH-responsive tannin was adopted. The slow-release and pH-responsiveness of the nanocomposite were improved by loading pyrazolestrobin and modifying with tannin.
Benefits of technology
It improves the slow-release and pH response ability of pyrazolestrobin, extends its effectiveness period, and enhances its antifungal biological activity, thereby improving efficient utilization in the field of fungal disease prevention and control.
✦ Generated by Eureka AI based on patent content.
Abstract
The invention discloses a preparation method and application of a pH response type tannic acid modified pyraclostrobin metal organic framework nano-composite. The preparation method comprises the following steps: constructing a pyraclostrobin metal organic framework nano-composite by using pyraclostrobin, dimethylimidazole and zinc acetate, and then carrying out interface function modification on the pyraclostrobin-loaded metal organic framework nano-composite by using tannic acid to prepare the tannic acid modified pyraclostrobin metal organic framework nano-composite. The tannic acid modified pyraclostrobin metal organic framework nano-composite endows the pyraclostrobin with the characteristics of sustained and controlled release and pH environment response, meanwhile, Botrytis cinerea thalli are caused to generate excessive active oxygen, and the efficient utilization of the pyraclostrobin in the field of fungal disease prevention and control is enhanced. The metal organic framework nano-composite and the tannic acid have degradability and biocompatibility, and the metal organic framework nano-composite is low in preparation cost, simple in process and suitable for popularization and application.
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