Multi-marker kit device for early screening of cancers and use method of multi-marker kit device

By designing a portable multimarker kit device, combined with a disinfection system and a joint detection algorithm, the problem of hospital infection prevention and control in traditional cancer screening equipment at outdoor screening points has been solved, and efficient and accurate early cancer screening has been achieved.

CN120427912APending Publication Date: 2025-08-05JIANGSU MODI BIOTECHNOLOGY CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202510560225.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-30
Publication Date
2025-08-05

AI Technical Summary

Technical Problem

Traditional cancer screening equipment is difficult to ensure standardized hospital infection prevention and control measures in outdoor screening points or temporary medical places, and the testing equipment is complex and inconvenient to carry, which affects the reliability and timeliness of testing.

Method used

A multi-marker kit device including a centrifuge, operating table, centrifugal limit tube and electric slide rail is designed, equipped with a disinfection system, and convenient disinfection processing is achieved through the electric slide rail and the rotary control plate, and the detection accuracy is improved in combination with a joint detection algorithm.

Benefits of technology

It has achieved the standard implementation of hospital infection prevention and control measures in outdoor screening points or temporary medical places, improved the accuracy and reliability of early cancer screening, reduced the false positive and false negative rates, and the equipment is easy to carry and operate.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN120427912A_ABST
    Figure CN120427912A_ABST
Patent Text Reader

Abstract

The invention discloses a multi-marker kit device for early cancer screening and a use method, and relates to the technical field of cancer screening, the device comprises a centrifuge, an operation table, a centrifugal limiting tube and an electric slide rail; the bottom end of the centrifugal machine is fixedly connected with an operation table; a plurality of groups of centrifugal limiting pipes are fixedly connected into the centrifugal machine; an electric sliding rail is fixedly connected to the side, close to the centrifugal machine, of the top end of the operation table. A cleaning rod at the bottom of a motor is inserted into a centrifugal limiting pipe through an electric sliding rail, the cleaning rod is rotated through a first motor, the interior of the centrifugal limiting pipe can be disinfected through rotation of the cleaning rod, a rotary control disc is rotated through the motor, and the centrifugal limiting pipe in the centrifugal machine is disinfected through the cleaning rod in sequence; the centrifugal machine can be disinfected while being convenient to carry, can be conveniently used in outdoor screening points or temporary medical places, is not limited by environmental conditions and equipment, and can ensure that standard hospital infection prevention and control measures are implemented.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The present invention relates to the technical field of cancer screening, and in particular to a multi-marker kit device for early cancer screening and a method of use. Background Art

[0002] Cancer is one of the leading causes of death worldwide. Its early detection and treatment are crucial to improving patients' survival rate and quality of life. Patients with early-stage cancer usually have a higher cure rate and longer survival, while the treatment effect of late-stage cancer is often poor and patients suffer greater pain. Therefore, carrying out early cancer screening and timely detection of potential cancer risks are of great value in reducing cancer mortality and alleviating the social medical burden.

[0003] Traditional cancer screening methods have some limitations and cannot meet the early screening needs of large populations. On the one hand, the accuracy of single marker detection is insufficient, and false positive and false negative results are prone to occur, affecting the reliability of diagnosis. On the other hand, the detection equipment is often complex and inconvenient to carry, and needs to be operated in a professional laboratory, which limits its application in primary medical care and on-site testing. In addition, the traditional detection process is usually cumbersome and time-consuming. It may take several days from sample collection to result reporting, which cannot provide patients with diagnostic information in a timely manner, delaying the patient's further diagnosis and treatment.

[0004] Although some portable cancer screening devices have mobile detection functions, they must strictly follow post-operative disinfection procedures to prevent cross-contamination. Taking the centrifuge as an example, ultraviolet disinfection and surface sterilization are required after routine operations. However, in outdoor screening points or temporary medical facilities, due to environmental conditions and equipment limitations, it is difficult to ensure the implementation of standardized hospital infection prevention and control measures, and there are potential medical safety risks. Summary of the Invention

[0005] The purpose of the present invention is to provide a multi-marker kit device and method of use for early cancer screening, so as to solve the technical problem in the prior art that it is difficult to ensure the implementation of standardized hospital infection prevention and control measures in outdoor screening points or temporary medical facilities due to environmental conditions and equipment limitations.

[0006] The technical problem to be solved by the present invention can be achieved through the following technical solutions:

[0007] A multi-marker test kit device for early cancer screening, comprising a centrifuge, an operating table, a centrifugal limiting tube and an electric slide;

[0008] The bottom end of the centrifuge is fixedly connected to an operating table; multiple groups of centrifugal limit tubes are fixedly connected to the interior of the centrifuge; an electric slide rail is fixedly connected to the top side of the operating table close to the centrifuge; an electric push rod is slidably connected to the side end of the electric slide rail; a motor is fixedly connected to the side end of the electric push rod; a rotary control disk is fixedly connected to the bottom output end of the motor; a No. 1 motor is fixedly connected to the interior of the rotary control disk; a cleaning rod is connected to the output end of the No. 1 motor, and the cleaning rod is arranged above the centrifugal limit tube.

[0009] As a further solution of the present invention: a disinfection box is fixedly connected to the top of the operating table; a water pump is fixedly connected to the interior of the disinfection box; and a nozzle is fixedly connected to the top of the water pump.

[0010] As a further solution of the present invention: a No. 2 motor is fixedly connected to one side of the No. 1 motor inside the rotary control disk; and a drying cotton swab is connected to the bottom end of the No. 2 motor.

[0011] As a further solution of the present invention: a heater is fixedly connected to the interior of the rotating control disk; a heating wire is fixedly connected to the side end of the heating machine; a heat-conducting wire is fixedly connected to the interior of the drying cotton swab, and the heat-conducting wire is arranged below the heating wire; a plurality of groups of heating ring wires are fixedly connected to the interior of the drying cotton swab, and the heating ring wires are connected to the heat-conducting wire; a cylinder is fixedly connected to the interior of the rotating control disk, and the bottom end of the cylinder is connected to the heating wire.

[0012] As a further solution of the present invention: the output end of the second motor is fixedly connected to a positioning plug; the interior of the drying cotton swab is fixedly connected to a magnet sheet, and the magnet sheet corresponds to the positioning plug.

[0013] A method for using a multi-marker kit for early cancer screening comprises the following steps:

[0014] S1. Collect a biological sample from the patient, such as blood, pleural effusion, or ascites, using a portable sample collection device and placing the biological sample in a specific sample tube. The sample collection device uses a disposable sampling head to ensure that the sample collection is contaminant-free. The biological sample tube is then placed in a centrifuge. The centrifuge automatically adjusts the speed and time according to the type of biological sample to centrifuge the biological sample to separate the cellular and liquid components in the biological sample and obtain a supernatant.

[0015] S2. Use a sample transfer device to accurately transfer the supernatant to a multi-marker detection device. Strictly control the sample volume during the transfer process to ensure the accuracy of the test results. The multi-marker detection device detects multiple cancer-related markers in the sample, including protein markers, gene markers, and metabolite markers, using advanced detection technology and highly specific detection reagents to accurately determine the content or expression level of the markers.

[0016] S3. Compare and analyze the test reagent results with the preset threshold or reference range to comprehensively judge whether the sample presents an early risk of cancer. The data storage and transmission function of the multi-marker detection device can transmit the test results to the mobile terminal or cloud platform in real time, which is convenient for doctors and patients to view. After each centrifugation operation and detection process is completed, use a disinfection device to fully disinfect the centrifuge device and other reusable device components, using an environmentally friendly and efficient disinfection method to ensure safety for next use and prevent cross contamination between different samples.

[0017] As a further solution of the present invention: in the multi-marker detection step, a combined detection algorithm is used to comprehensively analyze the detection results of multiple markers, taking into account the correlation and synergy between the markers, so as to improve the accuracy and reliability of early cancer screening. The combined detection algorithm is based on a large amount of clinical data and statistical models, and can effectively reduce the incidence of false positives and false negatives.

[0018] As a further solution of the present invention: During the sample collection and testing process, the samples are monitored and quality controlled in real time to ensure the integrity of the samples and the stability of the testing conditions. For example, parameters such as the temperature, pH value, and integrity of the samples are monitored. Once an abnormality is found, adjustments or re-collection of the samples are made in a timely manner to ensure the reliability of the test results.

[0019] The beneficial effects of the present invention are as follows: the motor is moved to the top of the centrifuge by the electric push rod, and the cleaning rod at the bottom of the motor is inserted into the interior of the centrifuge limit tube by the electric slide rail. The cleaning rod is made of sponge material, and the surface of the cleaning rod is sprayed with disinfectant, which is % ethanol. After the cleaning rod is inserted into the interior of the centrifuge limit tube, the cleaning rod is rotated by motor No. 1. The rotation of the cleaning rod can disinfect the interior of the centrifuge limit tube, and then the electric slide rail moves the cleaning rod upward, and the rotary control disk is rotated by the motor, so that the cleaning rod can disinfect the centrifuge limit tube inside the centrifuge in sequence, so that the centrifuge is easy to carry and can be disinfected at the same time, and is convenient for use in outdoor screening points or temporary medical places. It is not limited by environmental conditions and equipment limitations, and can ensure the implementation of standardized hospital infection prevention and control measures. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The present invention will be further described below with reference to the accompanying drawings.

[0021] Figure 1 It is a flow chart of the method of the present invention;

[0022] Figure 2 It is a three-dimensional diagram of the overall structure of the present invention;

[0023] Figure 3 It is a schematic structural diagram of the centrifuge in the present invention;

[0024] Figure 4 It is a structural schematic diagram of the disinfection box in the present invention;

[0025] Figure 5 This invention Figure 3 Enlarged view of point A in the middle;

[0026] In the figure: 1. Operating table; 2. Centrifuge; 3. Centrifugal limit tube; 4. Electric slide rail; 5. Electric push rod; 6. Motor; 7. Rotary control panel; 8. Motor No. 1; 9. Cleaning rod; 10. Motor No. 2; 11. Positioning plug; 12. Drying cotton swab; 13. Heating machine; 14. Heating wire; 15. Thermal wire; 16. Heating ring wire; 17. Cylinder; 18. Disinfection box; 19. Water pump; 20. Nozzle. DETAILED DESCRIPTION

[0027] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative efforts shall fall within the scope of protection of the present invention.

[0028] like Figure 1-Figure 5 As shown, a multi-marker kit device for early cancer screening includes a centrifuge 2, an operating table 1, a centrifugal limiting tube 3 and an electric slide 4;

[0029] The bottom end of the centrifuge 2 is fixedly connected to an operating table 1; a plurality of sets of centrifugal limit tubes 3 are fixedly connected to the interior of the centrifuge 2; an electric slide rail 4 is fixedly connected to the top side of the operating table 1 close to the centrifuge 2; an electric push rod 5 is slidably connected to the side end of the electric slide rail 4; a motor 6 is fixedly connected to the side end of the electric push rod 5; a rotary control disk 7 is fixedly connected to the bottom output end of the motor 6; a No. 1 motor 8 is fixedly connected to the interior of the rotary control disk 7; a cleaning rod 9 is connected to the output end of the No. 1 motor 8, and the cleaning rod 9 is arranged above the centrifugal limit tube 3.

[0030] At work, cancer has shown a significantly higher incidence in the elderly population. However, due to objective factors such as mobility difficulties and traffic obstructions, coupled with the resistance of some elderly people to traditional medical examinations, the early cancer screening rate in this group has been at a low level for a long time. Clinical data show that about 35% of elderly cancer patients delay treatment due to missing the golden screening window. By carrying out regional screening services through mobile medical vehicles equipped with portable intelligent detection equipment, combined with AI-assisted diagnosis systems and cloud-based expert consultation mechanisms, an integrated "screening-early warning-referral" elderly health protection network can be established. This innovative model of "sinking medical resources" can not only increase the early detection rate of malignant tumors by more than 35%, but also establish dynamic health records through regular health monitoring, providing a replicable solution for promoting the healthy aging strategy, which has important public health value. Separation is required during the detection process, and the separation equipment needs to be disinfected and cleaned. In order to ensure the detection Accuracy, the sample is placed in the interior of the centrifuge 2 for separation processing, after the centrifuge 2 is turned on, the motor 6 is moved to the top of the centrifuge 2 by the electric push rod 5, and the cleaning rod 9 at the bottom of the motor 6 is inserted into the interior of the centrifugal limiting tube 3 through the electric slide 4. The cleaning rod 9 is made of sponge material, and the surface of the cleaning rod 9 is sprayed with disinfectant, which is 75% ethanol. After the cleaning rod 9 is inserted into the interior of the centrifugal limiting tube 3, the cleaning rod 9 is rotated by the No. 1 motor 8. The rotation of the cleaning rod 9 can disinfect the inside of the centrifugal limiting tube 3, and then the electric slide 4 moves the cleaning rod 9 upward, and the rotary control disk 7 is rotated by the motor 6, so that the cleaning rod 9 disinfects the centrifugal limiting tube 3 inside the centrifuge 2 in sequence, making the centrifuge 2 easy to carry and can also be disinfected, and is convenient for use in outdoor screening points or temporary medical places, without being limited by environmental conditions and equipment limitations, and can ensure the implementation of standardized hospital infection prevention and control measures;

[0031] A disinfection box 18 is fixedly connected to the top of the operating table 1 ; a water pump 19 is fixedly connected to the interior of the disinfection box 18 ; and a nozzle 20 is fixedly connected to the top of the water pump 19 .

[0032] A large amount of 75% ethanol disinfectant is stored inside the disinfection box 18. When the cleaning rod 9 finishes cleaning the centrifugal limit tube 3, the cleaning rod 9 is inserted into the disinfection box 18 through the cooperation of the electric slide rail 4 and the electric push rod 5. At this time, the cleaning rod 9 is located on one side of the nozzle 20. The liquid is pumped into the nozzle 20 through the water pump 19, and the nozzle 20 sprays the disinfectant on the surface of the cleaning rod 9. The rotation of the No. 1 motor 8 can make the surface of the cleaning rod 9 evenly coated, which is convenient for disinfection next time.

[0033] A second motor 10 is fixedly connected to one side of the first motor 8 inside the rotary control disk 7 ; a drying cotton swab 12 is connected to the bottom end of the second motor 10 .

[0034] After the cleaning rod 9 disinfects the centrifugal limiting tube 3, some disinfectant will remain inside the centrifugal limiting tube 3. The drying cotton swab 12 is made of cotton. After the rotary control disk 7 moves downward, the drying cotton swab 12 is inserted into the disinfected centrifugal limiting tube 3. The drying cotton swab 12 can be rotated inside the centrifugal limiting tube 3 by the rotation of the No. 2 motor 10. The rotation of the drying cotton swab 12 can absorb the residual liquid inside the centrifugal limiting tube 3.

[0035] A heater 13 is fixedly connected to the interior of the rotating control disk 7; a heating wire 14 is fixedly connected to the side end of the heating machine 13; a heat-conducting wire 15 is fixedly connected to the interior of the drying cotton swab 12, and the heat-conducting wire 15 is arranged below the heating wire 14; a plurality of groups of heating ring wires 16 are fixedly connected to the interior of the drying cotton swab 12, and the heating ring wires 16 are connected to the heat-conducting wire 15; a cylinder 17 is fixedly connected to the interior of the rotating control disk 7, and the bottom end of the cylinder 17 is connected to the heating wire 14.

[0036] The heating wire 14 can be heated by the heating machine 13, and the heating wire 14 is connected and contacted with the heat-conducting wire 15. The heat of the heating wire 14 will be transferred to the heat-conducting wire 15, and the heat-conducting wire 15 will then transfer and diffuse the heat to the drying cotton swab 12, so that the drying cotton swab 12 is always kept in a dry state, and the centrifugal limiting tube 3 can be liquid-absorbed; when the drying cotton swab 12 needs to be rotated, the position of the heating wire 14 is changed by the cylinder 17, so that the heating wire 14 is away from the heat-conducting wire 15, and the drying cotton swab 12 can rotate normally at this time; when the drying cotton swab 12 stops operating, the position of the heating wire 14 is reset by the cylinder 17, so that the heating wire 14 is in contact with the heat-conducting wire 15, thereby preventing the rotation of the drying cotton swab 12 from accidentally touching the heating wire 14;

[0037] A positioning plug 11 is fixedly connected to the output end of the second motor 10 ; a magnet is fixedly connected to the interior of the drying cotton swab 12 , and the magnet corresponds to the positioning plug 11 .

[0038] Both the drying cotton swab 12 and the cleaning rod 9 need to be maintained and replaced regularly. There are magnet sheets inside the drying cotton swab 12 and the cleaning rod 9. The magnet sheets are connected to the positioning plug 11 through magnetic attraction. The position of the drying cotton swab 12 is fixed by the positioning plug 11. When the drying cotton swab 12 needs to be disassembled, it can be pulled out.

[0039] A method for using a multi-marker kit device for early cancer screening comprises the following steps:

[0040] S1. Collect a biological sample from a patient, such as blood, pleural effusion, or ascites, using a portable sample collection device. The sample is placed in a specific sample tube. The sample collection device uses a disposable sampling head to ensure contamination-free sample collection. The biological sample tube is then placed in a centrifuge 2. The centrifuge 2 automatically adjusts the speed and time according to the type of biological sample to centrifuge the biological sample, separating the cellular and liquid components in the biological sample to obtain a supernatant.

[0041] S2. Use a sample transfer device to accurately transfer the supernatant to a multi-marker detection device. Strictly control the sample volume during the transfer process to ensure the accuracy of the test results. The multi-marker detection device detects multiple cancer-related markers in the sample, including protein markers, gene markers, and metabolite markers, using advanced detection technology and highly specific detection reagents to accurately determine the content or expression level of the markers.

[0042] S3. Compare and analyze the test reagent results with the preset threshold or reference range to comprehensively judge whether the sample presents an early risk of cancer. The data storage and transmission function of the multi-marker detection device can transmit the test results to the mobile terminal or cloud platform in real time, which is convenient for doctors and patients to view. After each centrifugation operation and detection process is completed, use a disinfection device to fully disinfect the centrifuge device and other reusable device components, using an environmentally friendly and efficient disinfection method to ensure safety for next use and prevent cross contamination between different samples.

[0043] As a further solution of the present invention: in the multi-marker detection step, a combined detection algorithm is used to comprehensively analyze the detection results of multiple markers, taking into account the correlation and synergy between the markers, so as to improve the accuracy and reliability of early cancer screening. The combined detection algorithm is based on a large amount of clinical data and statistical models, and can effectively reduce the incidence of false positives and false negatives.

[0044] As a further solution of the present invention: During the sample collection and testing process, the samples are monitored and quality controlled in real time to ensure the integrity of the samples and the stability of the testing conditions. For example, parameters such as the temperature, pH value, and integrity of the samples are monitored. Once an abnormality is found, adjustments or re-collection of the samples are made in a timely manner to ensure the reliability of the test results.

[0045] The working principle of the invention: Cancer has a significantly higher incidence rate in the elderly population. However, due to objective factors such as mobility difficulties and traffic obstructions, coupled with the resistance of some elderly people to traditional medical examinations, the early cancer screening rate of this group has been low for a long time; clinical data show that about 35% of elderly cancer patients delay treatment due to missing the golden screening window period; through mobile medical vehicles equipped with portable intelligent detection equipment to carry out regional screening services, combined with AI-assisted diagnosis systems and cloud-based expert consultation mechanisms, an integrated "screening-early warning-referral" elderly health protection network can be constructed; this innovative model of "sinking medical resources" can not only increase the early detection rate of malignant tumors by more than 35%, but also establish dynamic health through regular health monitoring. Archives provide replicable solutions for promoting the healthy aging strategy and have important public health value; separation is required during the detection process, and the separation equipment needs to be disinfected and cleaned. In order to ensure the accuracy of the detection, the sample is placed in the interior of the centrifuge 2 for separation processing. After the centrifuge 2 is opened, the motor 6 is moved to the top of the centrifuge 2 by the electric push rod 5, and the cleaning rod 9 at the bottom of the motor 6 is inserted into the interior of the centrifugal limit tube 3 through the electric slide 4. The cleaning rod 9 is made of sponge material, and the surface of the cleaning rod 9 is sprayed with disinfectant, which is 75% ethanol. After the cleaning rod 9 is inserted into the interior of the centrifugal limit tube 3, the cleaning rod 9 is rotated by the No. 1 motor 8. The rotation of the cleaning rod 9 can disinfect the interior of the centrifugal limit tube 3, and then the electric slide The rail 4 moves the cleaning rod 9 upwards, and the motor 6 rotates the rotary control disk 7, so that the cleaning rod 9 disinfects the centrifugal limiting tube 3 inside the centrifuge 2 in sequence, so that the centrifuge 2 can be carried conveniently and can be disinfected at the same time, and is convenient for use in outdoor screening points or temporary medical places, without being restricted by environmental conditions and equipment limitations, and can ensure the implementation of standardized hospital infection prevention and control measures; after the cleaning rod 9 disinfects the centrifugal limiting tube 3, some disinfectant will remain inside the centrifugal limiting tube 3, and the drying cotton swab 12 is made of cotton material. When the rotary control disk 7 moves downward, the drying cotton swab 12 will be inserted into the disinfected centrifugal limiting tube 3, and the drying cotton swab 12 can be rotated inside the centrifugal limiting tube 3 by the rotation of the No. 2 motor 10, and the rotation of the drying cotton swab 12 can The residual liquid inside the limiting tube 3 is absorbed; the heating wire 14 can be heated by the heating machine 13, and the heating wire 14 is connected and contacted with the heat-conducting wire 15. The heat of the heating wire 14 will be transferred to the heat-conducting wire 15, and the heat-conducting wire 15 will then transfer and diffuse the heat to the drying cotton swab 12, so that the drying cotton swab 12 is always kept in a dry state, and the liquid can be absorbed by the centrifugal limiting tube 3; when the drying cotton swab 12 needs to be rotated, the position of the heating wire 14 is changed by the cylinder 17, so that the heating wire 14 is away from the heat-conducting wire 15, and the drying cotton swab 12 can rotate normally at this time. When the drying cotton swab 12 stops operating, the position of the heating wire 14 is reset by the cylinder 17, so that the heating wire 14 is in contact with the heat-conducting wire 15, to avoid the rotation of the drying cotton swab 12 accidentally touching the heating wire 14;Both the drying swab 12 and the cleaning swab 9 require regular maintenance and replacement. Magnets are located inside each swab, which connects to a positioning block 11 through magnetic attraction. The positioning block 11 secures the position of the drying swab 12 and allows it to be removed when needed. The disinfection box 18 contains a large amount of 75% ethanol disinfectant. Once the cleaning swab 9 has finished cleaning the centrifugal limit tube 3, the electric slide 4 and electric push rod 5 cooperate to insert the cleaning swab 9 into the disinfection box 18. The cleaning swab 9 is now positioned to one side of the nozzle 20. Liquid is pumped into the nozzle 20 via the water pump 19, which then sprays disinfectant onto the surface of the cleaning swab 9. The rotation of the first motor 8 evenly coats the surface of the cleaning swab 9, facilitating disinfection for the next step.

[0046] The above is a detailed description of an embodiment of the present invention. However, the content described is only a preferred embodiment of the present invention and should not be considered to limit the scope of the present invention. All equivalent changes and improvements made within the scope of the present invention should still fall within the scope of the patent coverage of the present invention.

Claims

1. A multi-marker kit device for early cancer screening, characterized in that: It comprises a centrifuge (2), an operating table (1), a centrifugal limiting tube (3) and an electric slide rail (4); The bottom end of the centrifuge (2) is fixedly connected to an operating table (1); a plurality of centrifugal limit tubes (3) are fixedly connected inside the centrifuge (2); an electric slide rail (4) is fixedly connected to the top of the operating table (1) on the side close to the centrifuge (2); an electric push rod (5) is slidably connected to the side end of the electric slide rail (4); a motor (6) is fixedly connected to the side end of the electric push rod (5); a rotary control disk (7) is fixedly connected to the bottom output end of the motor (6); a No. 1 motor (8) is fixedly connected inside the rotary control disk (7); a cleaning rod (9) is connected to the output end of the No. 1 motor (8), and the cleaning rod (9) is arranged above the centrifugal limit tube (3).

2. A multi-marker kit device for early cancer screening according to claim 1, characterized in that: A disinfection box (18) is fixedly connected to the top of the operating table (1); a water pump (19) is fixedly connected inside the disinfection box (18); and a nozzle (20) is fixedly connected to the top of the water pump (19).

3. The multi-marker kit device for early cancer screening according to claim 1, characterized in that: A second motor (10) is fixedly connected to one side of the first motor (8) inside the rotary control disk (7); and a drying cotton swab (12) is connected to the bottom end of the second motor (10).

4. The multi-marker kit device for early cancer screening according to claim 1, characterized in that: A heating machine (13) is fixedly connected to the interior of the rotary control disk (7); a heating wire (14) is fixedly connected to the side end of the heating machine (13); a heat-conducting wire (15) is fixedly connected to the interior of the drying cotton swab (12), and the heat-conducting wire (15) is arranged below the heating wire (14); a plurality of groups of heating ring wires (16) are fixedly connected to the interior of the drying cotton swab (12), and the heating ring wires (16) are connected to the heat-conducting wire (15); a cylinder (17) is fixedly connected to the interior of the rotary control disk (7), and the bottom end of the cylinder (17) is connected to the heating wire (14).

5. The multi-marker kit device for early cancer screening according to claim 3, characterized in that: The output end of the second motor (10) is fixedly connected with a positioning plug (11); the interior of the drying cotton swab (12) is fixedly connected with a magnet sheet, which corresponds to the positioning plug (11).

6. A method for using a multi-marker kit for early cancer screening, suitable for the multi-marker kit device for early cancer screening as claimed in claim 1, characterized in that: The following steps are involved: S1. Collect biological samples from patients, such as blood, pleural effusion, or ascites, using a portable sample collection device, and place the biological samples in a specific sample tube. The sample collection device uses a disposable sampling head to ensure that the sample collection is contaminant-free; then place the biological sample tube in a centrifuge (2). The centrifuge (2) automatically adjusts the speed and time according to the type of biological sample, centrifuges the biological sample, separates the cell and liquid components in the biological sample, and obtains a supernatant; S2. Use a sample transfer device to accurately transfer the supernatant to a multi-marker detection device. Strictly control the sample volume during the transfer process to ensure the accuracy of the test results. The multi-marker detection device detects multiple cancer-related markers in the sample, including protein markers, gene markers, and metabolite markers, using advanced detection technology and highly specific detection reagents to accurately determine the content or expression level of the markers. S3. Compare and analyze the test results with the preset threshold or reference range to comprehensively determine whether the sample presents an early cancer risk. The data storage and transmission function of the multi-marker detection device can transmit the test results in real time to a mobile terminal or cloud platform for easy viewing by doctors and patients; After each centrifugation operation and testing process is completed, the centrifuge device and other reusable device components are thoroughly disinfected using a disinfection device. This environmentally friendly and efficient disinfection method ensures safety for next use and prevents cross-contamination between different samples.

7. The multi-marker kit method for early cancer screening according to claim 6, characterized in that: In the multi-marker detection step, a combined detection algorithm is used to comprehensively analyze the detection results of multiple markers, taking into account the correlation and synergy between the markers to improve the accuracy and reliability of early cancer screening. The combined detection algorithm is based on a large amount of clinical data and statistical models, and can effectively reduce the incidence of false positives and false negatives.

8. The multi-marker kit method for early cancer screening according to claim 6, characterized in that: During the sample collection and testing process, samples are monitored and quality controlled in real time to ensure the integrity of the samples and the stability of the testing conditions. For example, parameters such as sample temperature, pH value and integrity are monitored. Once abnormal conditions are found, adjustments are made or samples are recollected in a timely manner to ensure the reliability of the test results.