Detection device

By designing blood simulation fluid, dialysate simulated fluid and flow control components in the blood purification device, the flow difference problem in the flow uniformity detection of blood and dialysate is solved, and more accurate test results are achieved, ensuring the blood purification device's Flow uniformity assessment.

CN222130675UActive Publication Date: 2024-12-10SHANDONG WEIGAO BLOOD PURIFICATION PRODUCTS CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202323445472.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2023-12-18
Publication Date
2024-12-10
Estimated Expiration
2033-12-18

AI Technical Summary

Technical Problem

When the existing blood purification device detects the flow uniformity of blood and dialysate, it cannot effectively regulate the flow rate at the blood chamber outlet and dialysate chamber outlet, resulting in a difference in flow rate caused by transmembrane transportation, affecting the determination of sampling time interval and test results. Accuracy.

Method used

A detection device is designed, including a blood simulated fluid device, a dialysate simulated fluid device, a flow control component, a tracer syringe, a sensing pool and a detection control component, and the blood and dialysate are controlled through components such as peristaltic pumps and duplex pumps. Flow rate to ensure that the outlet flow rate of the dialysate chamber is consistent with the preset flow rate. Use a tracer to detect the liquid concentration and record the test data to calculate the liquid flow uniformity of the blood purification device.

Benefits of technology

By accurately controlling the outlet flow of the dialysate simulated liquid, the flow rate difference caused by transmembrane transportation is avoided, the accuracy of the test is improved, and the consistency of sampling conditions and the accuracy of the test results are ensured.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN222130675U_ABST
    Figure CN222130675U_ABST
Patent Text Reader

Abstract

The utility model discloses a detection device, which relates to the technical field of medical instruments and comprises a blood purification device, a detection device, a detection device, a detection device and a control device, and is characterized in that the blood purification device is provided with a blood chamber inlet, a blood chamber outlet, a dialysate chamber inlet and a dialysate chamber outlet; the blood simulation liquid device is communicated with the blood chamber inlet through a first peristaltic pump; the dialysate simulation liquid device is communicated with the dialysate chamber inlet, and a flow control assembly is arranged between the dialysate simulation liquid device and the blood purification device; the tracer injectors are arranged at an inlet of the blood chamber and an inlet of the dialysate chamber; the first waste liquid collecting device is respectively communicated with the blood chamber outlet and the dialysate chamber outlet; the sensing pool is communicated with the blood chamber outlet and the dialysate chamber outlet; the detection control assembly is used for controlling the time and the sample size of the tracer injector for injecting the tracer, detecting the concentration of the tracer in the liquid in the sensing pool, setting experimental data, and converting and recording the test data; through the arrangement, the uniform flowability of the dialyzer is accurately and effectively evaluated.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to a detection device. Background Art

[0002] The blood purification device is considered to be a special type of equipment that realizes the exchange of solutes and water between blood and dialysate. It contains a blood chamber and a dialysate chamber. Only when the blood chamber is in full contact with the liquid in the dialysate chamber can the removal efficiency of the blood purification device reach the highest level. However, in reality, the end cap, baffle design, filling density, and degree of curvature of the blood purification device will cause the dialysate and blood to preferentially pass through some channels with low resistance, which will cause the blood flow to be small in places with large dialysate flow. This flow mismatch has a great impact on the removal effect of the blood purification device. For this reason, some scholars have conducted research on the flow uniformity of blood purification devices in recent years.

[0003] The prior art (patent publication number: CN114577672A) discloses a flow uniformity detection device, but only uses a peristaltic pump before the entrance of the blood chamber and the dialysate chamber, and cannot adjust the blood chamber outlet flow and the dialysate chamber outlet flow, so it cannot avoid the phenomenon that the flow is inconsistent with the preset flow due to transmembrane transport, and cannot ensure the consistency of sampling conditions during sampling, thereby affecting the determination of the sampling time interval, and further causing the test result to be less accurate; the detection system of the device adopts an optical detection device, such as an ultraviolet spectrophotometer, etc., which cannot accurately detect low-concentration samples before the end of the detection, resulting in inaccurate sampling concentration, resulting in the variance cannot be an effective indicator for uniformity evaluation, thereby affecting the true evaluation of the flow uniformity of the dialyzer.

[0004] Therefore, how to accurately and effectively evaluate the uniform fluidity of the dialyzer is a technical problem that technicians in this field currently need to solve. Utility Model Content

[0005] The purpose of the present application is to provide a detection device that can accurately and effectively evaluate the uniform fluidity of a dialyzer.

[0006] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0007] A detection device, comprising:

[0008] The blood purification device is provided with a blood chamber inlet, a blood chamber outlet, a dialysate chamber inlet and a dialysate chamber outlet;

[0009] A blood simulating fluid device, connected to the blood chamber inlet via a first peristaltic pump, for providing blood simulating fluid;

[0010] A dialysate simulation liquid device is communicated with the dialysate chamber inlet and is used to provide dialysate simulation liquid. A flow control component for controlling the inflow and outflow of the dialysate simulation liquid is provided between the dialysate simulation liquid device and the blood purification device;

[0011] a tracer injector, provided at the blood chamber inlet and the dialysate chamber inlet, for injecting a tracer into the blood simulation fluid or the dialysate simulation fluid;

[0012] a first waste liquid collecting device, wherein the first waste liquid collecting device is connected to the blood chamber outlet and the dialysate chamber outlet respectively;

[0013] A sensing pool, connected to the blood chamber outlet and the dialysate chamber outlet;

[0014] The detection control component is used to control the time and injection volume of the tracer injected by the tracer injector, detect the concentration of the tracer in the liquid in the sensor pool, set experimental data, and convert and record test data.

[0015] Preferably, the detection control component comprises:

[0016] Data processors;

[0017] An electrochemical sensing detection probe, connected to the data processor via a circuit, and used to detect the concentration of the tracer in the liquid in the sensing cell;

[0018] The circuit control system is used to control the tracer injector to inject the tracer and perform sampling at the same time.

[0019] Preferably, the first waste liquid collecting device and the sensor pool are both connected to the blood chamber outlet through a first drainage channel, and the first waste liquid collecting device and the sensor pool are both connected to the dialysate chamber outlet through a second drainage channel.

[0020] Preferably, the blood simulation fluid is a glycerol solution with a mass fraction of 33%, and the dialysate simulation fluid is water for injection.

[0021] Preferably, the tracer syringe is 1 cm away from the blood chamber inlet and the dialysate chamber inlet.

[0022] Preferably, a liquid outflow outlet is provided at the bottom of the sensing pool for maintaining the flow of liquid therein.

[0023] Preferably, the flow control component is a compound pump, the dialysate chamber inlet is connected to the dialysate simulated fluid device via the compound pump, and the dialysate chamber outlet is connected to the second drainage channel via the compound pump.

[0024] Preferably, the flow control component comprises:

[0025] A second peristaltic pump is provided between the dialysate simulation fluid device and the dialysate chamber inlet;

[0026] The third peristaltic pump is arranged between the dialysate chamber outlet and the second drainage channel.

[0027] Preferably, the second peristaltic pump and the third peristaltic pump cooperate with each other to ensure that the outlet flow rate of the dialysate chamber is consistent with the set flow rate.

[0028] With respect to the above-mentioned background technology, the present application provides a detection device, comprising: a blood purification device, a blood simulation fluid device, a first peristaltic pump, a dialysate simulation fluid device, a flow control component, a tracer syringe, a first waste fluid collection device, a sensor pool and a detection control component; the blood purification device is provided with a blood chamber inlet, a blood chamber outlet, a dialysate chamber inlet and a dialysate chamber outlet; the blood simulation fluid device is connected to the blood chamber inlet through the first peristaltic pump and is used to provide blood simulation fluid; the dialysate simulation fluid device is connected to the dialysate chamber inlet and is used to provide dialysate simulation fluid, and the dialysate simulation fluid device and the blood purification device are connected. A flow control component is provided in the chamber for controlling the inflow and outflow flow of the dialysate simulation liquid; a tracer injector is arranged at the blood chamber inlet and the dialysate chamber inlet, and is used to inject the tracer into the blood simulation liquid or the dialysate simulation liquid; a first waste liquid collection device, the first waste liquid collection device is connected with the blood chamber outlet and the dialysate chamber outlet respectively; a sensing pool is connected with the blood chamber outlet and the dialysate chamber outlet; a detection control component is used to control the time and injection volume of the tracer injector to inject the tracer, detect the concentration of the tracer in the liquid in the sensing pool, set experimental data, and convert and record test data.

[0029] During the test, first check and connect the blood purification device, and test the blood simulation fluid and the dialysate simulation fluid separately; set the flow rates of the blood simulation fluid and the dialysate simulation fluid through the first peristaltic pump and the flow control component, set the tracer injection time and the detection time interval as well as the blood chamber capacity and the dialysate chamber capacity through the detection control component; after the setting is completed, start working, first test the dialysate chamber, then test the blood chamber, the blood chamber simulation fluid flows through the blood purification device through the peristaltic pump, and finally flows to the first waste liquid collection device, the dialysate simulation fluid also flows to the first waste liquid collection device through the blood purification device through the flow control component, and when the set time is reached, start testing the dialysate chamber, and the tracer injector automatically injects the tracer into the blood chamber. The tracer is automatically injected into the dialysate chamber entrance. At this time, the blood chamber simulation fluid flows normally to the first waste fluid collection device, and the dialysate simulation fluid flows into the sensor pool for data detection, which is then converted, recorded and processed by the data processor to output relevant results; then the tracer injector is controlled to automatically inject the tracer into the blood chamber entrance. At this time, the dialysate simulation fluid flows normally to the first waste fluid collection device, and the blood chamber simulation fluid flows into the sensor pool for data detection, which is then converted, recorded and processed by the data processor to output relevant results; finally, according to the pre-input blood chamber volume, flow rate and dialysate volume, flow rate, the final result is automatically calculated and output, and the liquid flow uniformity of the blood purification device is judged according to the final result.

[0030] Because the flow control component can control the consistency between the dialysate simulation fluid outlet flow and the preset flow, it avoids the inaccuracy of the test results caused by the flow difference caused by transmembrane transport, thereby greatly improving the accuracy of the test. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying any creative work.

[0032] Figure 1 A schematic diagram of the structure of a detection device provided by an embodiment of the utility model;

[0033] Figure 2 A schematic diagram of the structure of another embodiment of the detection device provided by the embodiment of the utility model;

[0034] in:

[0035] 1-blood purification device, 11-blood chamber inlet, 12-blood chamber outlet, 13-dialysis fluid chamber inlet, 14-dialysis fluid chamber outlet;

[0036] 2-blood simulation liquid device, 21-first peristaltic pump, 22-first liquid discharge channel;

[0037] 3-dialysis fluid simulation fluid device, 31-second drainage channel;

[0038] 41-compound pump, 45-second peristaltic pump, 46-third peristaltic pump;

[0039] 5-Tracer syringe;

[0040] 6- first waste liquid collection device;

[0041] 7-sensing pool, 71-liquid outlet;

[0042] 81-data processor, 82-electrochemical sensor detection probe, 83-circuit, 84-circuit control system. DETAILED DESCRIPTION

[0043] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0044] In order to enable those skilled in the art to better understand the present application, the present application is further described in detail below in conjunction with the accompanying drawings and specific implementation methods.

[0045] In the description of the present invention, it should be understood that the terms "up", "down", "front", "back", "left" and "right" etc. indicating directions or positional relationships are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the positions or elements referred to must have a specific direction, be constructed and operated in a specific direction, and therefore should not be understood as a limitation of the present invention.

[0046] See also Figure 1 to Figure 2The present embodiment provides a detection device, comprising: a blood purification device 1, a blood simulation fluid device 2, a first peristaltic pump 21, a dialysate simulation fluid device 3, a flow control component, a tracer syringe 5, a first waste fluid collection device 6, a sensor pool 7 and a detection control component; the blood purification device 1 is provided with a blood chamber inlet 11, a blood chamber outlet 12, a dialysate chamber inlet 13 and a dialysate chamber outlet 14; the blood simulation fluid device 2 is connected to the blood chamber inlet 11 through the first peristaltic pump 21, and is used to provide blood simulation fluid; the dialysate simulation fluid device 3 is connected to the dialysate chamber inlet 13, and is used to provide dialysate simulation fluid; the dialysate simulation fluid device 3 A flow control component for controlling the inflow and outflow of dialysate simulation fluid is provided between the blood purification device 1; a tracer injector 5 is provided at the blood chamber inlet 11 and the dialysate chamber inlet 13, and is used to inject tracers into the blood simulation fluid or the dialysate simulation fluid; a first waste liquid collection device 6, which is connected to the blood chamber outlet 12 and the dialysate chamber outlet 14 respectively; a sensor pool 7, which is connected to the blood chamber outlet 12 and the dialysate chamber outlet 14; a detection control component, which is used to control the time and injection volume of the tracer injected by the tracer injector 5, detect the concentration of the tracer in the liquid in the sensor pool 7, set experimental data, and convert and record test data.

[0047] Specifically, the blood purification device 1 is divided into a dialysate chamber and a blood chamber; the blood chamber inlet 11 and the blood chamber outlet 12 are respectively arranged at the two ends of the blood purification device 1, and the dialysate chamber inlet 13 and the dialysate chamber outlet 14 are arranged on the side of the blood purification device 1 in opposite directions, that is, the blood chamber inlet 11 and the dialysate chamber outlet 14 are arranged at the upper end and the upper end of the side of the blood purification device 1, and the blood chamber outlet 12 and the dialysate chamber outlet 14 are arranged at the lower end and the lower end of the side of the blood purification device 1.

[0048] The blood purification device 1, the blood simulation fluid device 2, the dialysate simulation fluid device 3, the first waste fluid collection device 6 and the sensor pool 7 are all connected by pipelines, wherein a first peristaltic pump 21 is provided on the pipeline between the blood purification device 1 and the blood simulation fluid device 2 for providing blood flow power, and a flow control component is provided on the pipeline connecting the dialysate chamber inlet 13 and the dialysate chamber outlet 14 on the blood purification device 1 for controlling the flow of the dialysate simulation fluid entering and flowing out of the dialysate chamber, maintaining the stability of the dialysate simulation fluid flow, balancing the difference between the flow caused by transmembrane transport and the set value, ensuring that the flow is the set value, and ensuring the accuracy of the sampling time interval.

[0049] It should be noted that after the blood purification device 1 is determined, the capacity of its dialysate chamber and blood chamber is also determined, that is, the total capacity of the dialysate chamber and blood chamber is certain. During the test, the flow control component maintains the stability of the dialysis simulation fluid flow, and the blood simulation fluid flow will also be stable.

[0050] Tracer injectors 5 are provided at both the blood chamber inlet 11 and the dialysate chamber inlet 13 . The blood simulation fluid flowing out of the blood chamber outlet 12 can be selectively discharged to the first waste fluid collection device 6 or the sensor pool 7 . The same is true for the dialysate simulation fluid discharged from the dialysate chamber outlet 14 .

[0051] The detection control component can detect the concentration of the tracer in the liquid discharged into the sensor pool 7, and convert and calculate through the set data to obtain the result, and then judge the uniform fluidity of the blood purification device 1.

[0052] Preferably, the detection control component includes: a data processor 81, an electrochemical sensing detection probe 82 and a circuit control system 84; the electrochemical sensing detection probe 82 is connected to the data processor 81 through a circuit 83, and is used to detect the concentration of the tracer in the liquid in the sensing cell 7; the circuit control system 84 is used to control the tracer injector 5 to inject the tracer and perform sampling work simultaneously.

[0053] In this embodiment, the data processor 81 can set test data such as experimental flow rate, sampling time interval, sampling time, etc., and has a built-in data recording and storage conversion system, which can realize the tracer concentration conversion, detection time interval, and total detection time recording of the electrochemical sensor probe detection, and automatically calculate and output the final result; the electrochemical sensor detection probe 82 can accurately detect the concentration of the tracer in the liquid, and transmit the data to the data processor 81, which is converted into signal intensity through a built-in linear equation and recorded; the circuit control system 84 is connected to the two tracer injectors 5, and is responsible for controlling the injection of tracers and sampling work at the same time.

[0054] Preferably, the first waste liquid collection device 6 and the sensor pool 7 are both connected to the blood chamber outlet 12 through the first drainage channel 22 , and the first waste liquid collection device 6 and the sensor pool 7 are both connected to the dialysate chamber outlet 14 through the second drainage channel 31 .

[0055] In this embodiment, the first drainage channel 22 and the second drainage channel 31 can be preferably opened or closed. When measuring the dialysate chamber, the waste liquid of the blood simulation fluid can be discharged through the first drainage channel 22, and the dialysate simulation fluid can be discharged into the sensor pool 7 through the second drainage channel 31 for testing; when measuring the blood chamber, the waste liquid of the dialysate simulation fluid can be discharged through the second drainage channel 31, and the blood simulation fluid can be discharged into the sensor pool 7 through the first drainage channel 22 for testing.

[0056] Preferably, the blood simulation fluid is a glycerol solution with a mass fraction of 33%, and the dialysate simulation fluid is water for injection.

[0057] It can be understood that the blood simulation fluid is composed of a glycerol solution with a mass fraction of 33%, which can simulate the viscosity of blood, and the dialysate simulation fluid is directly simulated by water for injection.

[0058] Preferably, the tracer syringe 5 is 1 cm away from the blood chamber inlet 11 and the dialysate chamber inlet 13 .

[0059] In this embodiment, the distance between the tracer syringe 5 and the blood chamber inlet 11 and the dialysate chamber inlet 13 is 1 cm. Of course, the distance can also be adjusted according to actual conditions.

[0060] Preferably, a liquid outflow port 71 is provided at the bottom of the sensing pool 7 for maintaining the flow of liquid therein.

[0061] It can be understood that in order to ensure the continuity of detection, the liquid in the detection pool needs to be kept flowing, and the liquid flowing through the electrochemical sensing detection probe 82 can flow out through this port.

[0062] Preferably, the flow control component is a compound pump, the dialysate chamber inlet is connected to the dialysate simulated fluid device via the compound pump, and the dialysate chamber outlet is connected to the second drainage channel via the compound pump.

[0063] Specifically, in the present embodiment, the pipe connected to the dialysate chamber inlet 13 and the pipe connected to the dialysate chamber outlet 14 through the second drainage channel all pass through the compound pump. The compound pump 41 can realize liquid delivery by utilizing two synchronously operating pistons through reciprocating motion, thereby controlling the consistency of the flow rate at the dialysate chamber outlet 14 with the preset flow rate, avoiding the flow difference caused by transmembrane transport, ensuring sampling under the same conditions, and thus determining the sampling time interval.

[0064] Preferably, the flow control component includes: a second peristaltic pump 45 and a third peristaltic pump 46; the second peristaltic pump 45 is arranged between the dialysate simulation fluid device 3 and the dialysate chamber inlet 13; the third peristaltic pump 46 is arranged between the dialysate chamber outlet 14 and the second drainage channel 31.

[0065] The present application also provides another embodiment, such as Figure 2 As shown, in another embodiment, a second peristaltic pump 45 is provided between the dialysate simulation fluid device 3 and the dialysate chamber inlet 13, and a third peristaltic pump 46 is provided between the dialysate chamber outlet 14 and the second drainage channel 31, wherein the second peristaltic pump 45 and the third peristaltic pump 46 can provide flow power for the dialysate simulation fluid according to the set dialysate flow rate.

[0066] Preferably, the second peristaltic pump 45 and the third peristaltic pump 46 cooperate with each other to ensure that the flow rate at the dialysate chamber outlet 14 is consistent with the set flow rate.

[0067] In this embodiment, the dialysate simulation fluid flow rate flowing through the second peristaltic pump 45 and the third peristaltic pump 46 can be set to ensure that the flow rate at the dialysate chamber outlet 14 is consistent with the set flow rate, thereby avoiding excessive dialysate flow rate caused by transmembrane transport, ensuring that the flow rate is the set value, and ensuring the accuracy of the sampling time interval.

[0068] In summary, the embodiment of the present application provides a detection device. During the detection, first check and connect the blood purification device 1, configure the corresponding simulated liquid in advance, and place it in the corresponding device. Set the flow of the blood chamber and the dialysate chamber during the experiment through the first peristaltic pump 21 and the retest pump, or set and control the flow of the blood chamber and the dialysate chamber during the experiment through the first peristaltic pump 21, the second peristaltic pump 45 and the third peristaltic pump 46. Both implementation methods can achieve the effect of controlling the flow of the dialysate simulated liquid, and then set the flow of the dialysate chamber and the blood through the data processor 81. The chamber test sequence, the tracer injection time and the detection time interval, the blood chamber capacity and the dialysate chamber capacity of the blood purification device 1, wherein in the present embodiment, the dialysate chamber is tested first, and then the blood chamber is tested, and then the switch is turned on to start working, the blood chamber simulation fluid flows through the blood purification device 1 through the first peristaltic pump 21, and is discharged to the first waste liquid collection device 6 through the first drainage channel 22; the dialysis simulation fluid flows through the dialysate chamber of the blood purification device 1 through the compound pump 41, and is discharged to the first waste liquid collection device 6 through the dialysate chamber outlet 14 to the second drainage channel 31.

[0069] When the set time is reached, the data processor 81 will control the tracer to automatically inject the tracer into the dialysate chamber inlet 13 through the circuit control system 84. At the same time, the data processor 81 starts to control the start of sampling and records data. At this time, the blood chamber simulation fluid normally flows to the first waste liquid collection device 6 through the first drainage channel 22, and the dialysate simulation fluid flows into the sensor pool 7 through the second drainage channel 31 for data detection, and then converted, recorded and processed by the data processor 81 to output relevant results; then the blood chamber is tested, and the data processor 81 controls the tracer through the circuit control system 84 The tracer is automatically injected into the blood chamber entrance 11, and the data processor 81 starts to control the sampling and record the data. At this time, the dialysate simulation liquid normally flows through the second drainage channel 31 to the first waste liquid collection device 6, and the blood chamber simulation liquid will flow into the sensor pool 7 through the first drainage channel 22 for data detection, and then converted, recorded and processed by the data processor 81, and the relevant results are output; finally, according to the pre-input blood chamber volume, flow rate and dialysate chamber volume, flow rate, the final result is automatically calculated and output, and the liquid flow uniformity of the blood purification device 1 is judged according to the final result.

[0070] In this way, the consistency of the dialysate simulation fluid outlet flow rate with the preset flow rate can be controlled through the flow control component, avoiding the inaccurate test results caused by the flow difference caused by transmembrane transport, thereby greatly improving the accuracy of the test.

[0071] The calculation principles and formulas used in this utility model are all existing technologies, which are as follows:

[0072] During the test, the electrochemical sensing probe 82 detects the concentration of the tracer in the dialysate or blood flowing into the sensing cell 7 and converts it into an intensity value through the data processor 81 to establish a time (t i )-Intensity(I i ) curve, and automatically calculate the average residence time using the following formula (1)

[0073]

[0074] The data processor 81 then inputs the dialysate chamber or blood chamber volume (V) and the dialysate chamber or blood chamber flow (Q) of the blood purification device 1, and the space time τ can be calculated according to the following formula (2).

[0075] τ=V / Q; (2)

[0076] Finally, the dimensionless residence time K of the fluid flow distribution curve is calculated according to the following formula (3).

[0077]

[0078] Generally speaking, if K is greater than 1, it indicates that there is a dead zone in the blood purification device 1 ; if K is less than 1, it indicates that there is a fast channel in the blood purification device 1 ; the closer the K value is to 1, the better the uniformity of the liquid flow in the blood purification device 1 .

[0079] It should be noted that, in this specification, relational terms such as first and second are merely used to distinguish one entity from other entities, but do not necessarily require or imply any actual relationship or order between these entities.

[0080] The above is a detailed introduction to the embodiments provided by the utility model. This article uses specific examples to illustrate the principles and implementation methods of the utility model. The description of the above embodiments is only used to help understand the method and core ideas of the utility model. It should be pointed out that for ordinary technicians in this technical field, without departing from the principles of the utility model, the utility model can also be improved and modified, and these improvements and modifications also fall within the scope of protection of the claims of the utility model.

Claims

1. A detection device, It is characterized in that include: A blood purification device (1) is provided with a blood chamber inlet (11), a blood chamber outlet (12), a dialysate chamber inlet (13) and a dialysate chamber outlet (14); A blood simulating fluid device (2), connected to the blood chamber inlet (11) via a first peristaltic pump (21), for providing blood simulating fluid; A dialysate simulation fluid device (3) is connected to the dialysate chamber inlet (13) and is used to provide dialysate simulation fluid. A flow control component for controlling the inflow and outflow of the dialysate simulation fluid is provided between the dialysate simulation fluid device (3) and the blood purification device (1); a tracer injector (5), arranged at the blood chamber inlet (11) and the dialysate chamber inlet (13), and used for injecting a tracer into the blood simulating fluid or the dialysate simulating fluid; A first waste liquid collection device (6), wherein the first waste liquid collection device (6) is connected to the blood chamber outlet (12) and the dialysate chamber outlet (14) respectively; A sensing pool (7) connected to the blood chamber outlet (12) and the dialysate chamber outlet (14); The detection control component is used to control the time and injection volume of the tracer injected by the tracer injector (5), detect the concentration of the tracer in the liquid in the sensor pool (7), set experimental data, and convert and record test data.

2. The detection device according to claim 1, It is characterized in that The detection control component comprises: Data processor (81); An electrochemical sensing detection probe (82) connected to the data processor (81) via a circuit (83) and used to detect the concentration of the tracer in the liquid in the sensing cell (7); The circuit control system (84) is used to control the tracer injector (5) to inject the tracer and perform sampling at the same time.

3. The detection device according to claim 1, It is characterized in that The first waste liquid collection device (6) and the sensor pool (7) are both connected to the blood chamber outlet (12) through a first drainage channel (22), and the first waste liquid collection device (6) and the sensor pool (7) are both connected to the dialysate chamber outlet (14) through a second drainage channel (31).

4. The detection device according to claim 1, It is characterized in that The blood simulation liquid is a glycerol solution with a mass fraction of 33%, and the dialysate simulation liquid is water for injection.

5. The detection device according to claim 1, It is characterized in that The tracer syringe (5) is 1 cm away from the blood chamber inlet (11) and the dialysate chamber inlet (13).

6. The detection device according to claim 1, It is characterized in that The bottom of the sensing pool (7) is provided with a liquid outflow outlet (71) for maintaining the flow of liquid inside the sensing pool (7).

7. The detection device according to claim 3, It is characterized in that The flow control component is specifically a compound pump (41), the dialysate chamber inlet (13) is connected to the dialysate simulation fluid device (3) via the compound pump (41), and the dialysate chamber outlet (14) is connected to the second drainage channel (31) via the compound pump (41).

8. The detection device according to claim 3, It is characterized in that The flow control component comprises: a second peristaltic pump (45), disposed between the dialysate simulation fluid device (3) and the dialysate chamber inlet (13); The third peristaltic pump (46) is arranged between the dialysate chamber outlet (14) and the second drainage channel (31).

9. The detection device according to claim 8, It is characterized in that The second peristaltic pump (45) and the third peristaltic pump (46) cooperate with each other to ensure that the flow rate at the dialysate chamber outlet (14) is consistent with the set flow rate.