Ultrafiltration centrifugal tube for centrifugal machine

Abstract

The utility model relates to the technical field of separation biochemical materials, in particular to an ultrafiltration centrifugal tube for a centrifugal machine. Comprising a shell and a filtering device installed in the shell, and the shell comprises a round-tube-shaped concentrated solution collecting tube and a tube cover screwed on the round-tube-shaped concentrated solution collecting tube in a threaded mode; the filter device comprises a filter element body which is of a blind-tube-shaped structure, two planes are symmetrically arranged on the two sides of the tail end of the filter element body, the two planes are each provided with a rectangular ultrafiltration membrane hole, a semi-cylindrical filter element supporting plate is arranged on the outer side of each ultrafiltration membrane hole, the side, on the ultrafiltration membrane holes, of each filter element supporting plate is a semi-cylindrical plane side, and the side, on the other side, of each filter element supporting plate is a rectangular plane side. A rectangular boss is arranged on the base, an ultrafiltration membrane is welded or glued on the boss, and a sealing ring is sleeved on the periphery of the rectangular boss. Flow guide holes are formed in the outer side of the filter element supporting plate, a plurality of flow guide grooves communicated with the filter element supporting plate are formed in the inner side, and a ventilation groove is formed in an annular boss arranged on the outer side of the open end of the filter element body. The filter device is plugged into the concentrated solution collecting pipe after being assembled and is in a micro-positive pressure state.

Description

Technical Field

[0001] The utility model relates to the technical field of separation of biochemical materials, in particular to an ultrafiltration centrifuge tube for a centrifuge. Background Art

[0002] Ultrafiltration, as a membrane separation technology, is widely used in the concentration, desalination and buffer exchange of biological samples. The filter membrane is usually made of polymer or ceramic materials with different pore sizes. Under the action of centrifugal force, when the solution passes through the filter membrane, large molecules are retained on the filter membrane according to the size of the molecules, while small molecules pass through the filter membrane into the centrifuge tube. In this way, the separation of substances of different molecular sizes in the solution is achieved.

[0003] The existing ultrafiltration centrifuge tubes have the problems of complex structure, complicated assembly, low recovery rate, large residual amount and protein adsorption. Therefore, the present invention provides an ultrafiltration centrifuge tube. Utility Model Content

[0004] The main purpose of the utility model is to provide an ultrafiltration centrifuge tube for a centrifuge, so as to effectively solve the problems raised in the background technology.

[0005] To achieve the above-mentioned purpose, the utility model adopts the following technical scheme: an ultrafiltration centrifuge tube for a centrifuge, comprising a shell and a filtering device installed in the shell, the shell comprising a circular tubular concentrate collection tube and a tube cover threadedly screwed thereon; the filtering device comprises a filter element main body, the filter element main body is a blind tube structure, and two planes are symmetrically opened on both sides of its tail end, and a rectangular ultrafiltration membrane hole is respectively arranged on the two planes, and a semi-cylindrical filter element support plate is arranged on the outside of the rectangular ultrafiltration membrane hole. The filter element support plate is a semi-cylindrical plane side on one side of the ultrafiltration membrane hole, and a rectangular boss is arranged on it, an ultrafiltration membrane is welded or glued on the boss, and a sealing ring is mounted around the rectangular boss.

[0006] Preferably, the filter element support plate is processed from a semi-cylinder, and a platform structure is provided in the middle of one side of the cylindrical surface of the semi-cylinder, with a semi-cylindrical surface retained at the front and rear ends respectively, the rear end surface of the rear semi-cylindrical surface being flush with the tail end of the semi-cylindrical surface, and a small platform is provided on the front side of the front semi-cylindrical surface, a groove is provided on the small platform close to the front semi-cylindrical surface, a plurality of guide holes are provided in the groove, and a plurality of guide grooves connected to the guide holes are provided on a rectangular boss provided on one side of the semi-cylindrical plane.

[0007] Preferably, the sealing ring is higher than a rectangular boss arranged on one side of the semi-cylindrical plane of the filter element support plate, and is pressed tightly against the four sides of the rectangular ultrafiltration membrane hole on the rear end plane of the filter element body.

[0008] Preferably, an annular boss is arranged outside the opening end of the filter element body, and an air-permeable groove is arranged on the annular boss.

[0009] Preferably, the filter device is inserted into the concentrate collection tube after assembly, the semi-cylindrical surface on the filter element support plate is close to the inner wall of the concentrate collection tube, presenting a slightly positive pressure state, the tail end of the filter element body is flush with the tube mouth of the concentrate collection tube, and the tube cover is screwed tightly on the concentrate collection tube.

[0010] When in use, load the biochemical solution into the filter element body, screw the tube cover onto the concentrated liquid collection tube, load it into the centrifuge, and achieve separation under high-speed centrifugation environment; the filtered solution flows into the concentrated liquid collection tube through the guide grooves and guide holes on the filter element support plate; after use, take out the filter device, pour out the concentrated macromolecular solution inside the filter element body, and what remains in the collection tube is the small molecule solution, thus achieving separation.

[0011] Beneficial effects of the utility model:

[0012] 1. The mouth of the filter element is designed with a breathable groove, so that the gas in the filter element can flow out smoothly when the filter element is inserted into the collection tube, and the installation is smooth. At the same time, there is a relay position when the filter element is taken out, so it is smooth to take out.

[0013] 2. The structure of the ultrafiltration centrifuge tube is simple, and the installation can be completed by using only one external connection process (connecting the ultrafiltration membrane with the filter element support plate).

[0014] 3. The filter element support plate and the inner wall of the concentrate collection tube are in interference fit, so that the filter element assembly and the filter element body are firmly sealed, and sealing can be achieved even in a high-speed centrifugal environment, thereby improving the recovery efficiency.

[0015] 4. The filter element assembly is suitable for existing centrifuge tube standards and is compatible with various brands of centrifuges, with good versatility;

[0016] 5. To assemble the filter element assembly, only 2 mold opening parts, 2 ultrafiltration membranes, and 2 sealing rings are required, which reduces costs. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Attached Figure 1 This is a three-dimensional diagram of the structure appearance of the utility model.

[0018] Attached Figure 2 It is an exploded view of the three-dimensional structure of the utility model.

[0019] Attached Figure 3 This is a three-dimensional structural diagram of the filter element main body of the utility model.

[0020] Attached Figure 4 This is a three-dimensional diagram of the back structure of the filter element support plate of the utility model.

[0021] Attached Figure 5 This is a front structural stereogram of the filter element support plate of the utility model.

[0022] Attached Figure 1 —5, tube cover 1, filter element body 2, ultrafiltration membrane 3, sealing ring 4, filter element support plate 5, concentrate collecting tube 6, guide groove 7, guide hole 8, air permeable groove 9, ultrafiltration membrane hole 10. DETAILED DESCRIPTION

[0023] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0024] Example 1

[0025] Attached Figure 1 As shown in FIG. 5 , an ultrafiltration centrifuge tube for a centrifuge comprises a shell and a filtering device installed in the shell, wherein the shell comprises a circular tubular concentrate collecting tube 6 and a tube cover 1 threadedly mounted thereon; the filtering device comprises a filter element body 2, which is a blind tube structure, and has two planes symmetrically provided on both sides of its tail end, each of which has a rectangular ultrafiltration membrane hole 10, and a semi-cylindrical filter element support plate 5 is provided on the outer side of the rectangular ultrafiltration membrane hole 10. The filter element support plate 5 is a semi-cylindrical plane side on one side of the ultrafiltration membrane hole 10, and a rectangular boss is provided on it, an ultrafiltration membrane 3 is welded or glued on the boss, and a sealing ring 4 is fitted around the rectangular boss.

[0026] The filter element support plate 5 is processed from a semi-cylinder, and a platform structure is provided in the middle of one side of the cylindrical surface of the semi-cylinder. A section of the semi-cylinder is retained at the front and rear ends. The rear end surface of the rear semi-cylinder is flush with the tail end of the semi-cylinder. A small platform is provided on the front side of the front semi-cylinder. A groove is provided at the position of the small platform close to the front semi-cylinder, and a plurality of guide holes 8 are provided in the groove. A plurality of guide grooves 7 connected to the guide holes 8 are provided on a rectangular boss provided on one side of the semi-cylinder plane.

[0027] The sealing ring 4 is higher than the rectangular boss arranged on one side of the semi-cylindrical plane of the filter element support plate 5, and is pressed tightly against the four sides of the rectangular ultrafiltration membrane hole on the plane of the tail end of the filter element body.

[0028] An annular boss is arranged outside the opening end of the filter element body 2 , and a venting groove 9 is arranged on the annular boss.

[0029] After the filtration device is assembled, it is inserted into the concentrated liquid collection tube 6, and the semi-cylindrical surface on the filter element support plate 5 is close to the inner wall of the concentrated liquid collection tube 6, presenting a slightly positive pressure state, the tail end of the filter element body 2 is flush with the tube mouth of the concentrated liquid collection tube 6, and the tube cover 1 is screwed on the concentrated liquid collection tube.

[0030] When in use, the biochemical solution is loaded into the filter element body 2, the tube cover 1 is screwed onto the concentrated liquid collecting tube 6, and loaded into the centrifuge to achieve separation under high-speed centrifugal environment; the filtered solution flows into the concentrated liquid collecting tube through the guide groove 7 and the guide hole 8 on the filter element support plate 5; after use, the filtering device is taken out, the concentrated macromolecular solution inside the filter element body 2 is poured out, and the small molecule solution remains in the collecting tube to achieve separation.

[0031] Beneficial effects of the utility model:

[0032] 1. The mouth of the filter element is designed with a breathable groove, so that the gas in the filter element can flow out smoothly when the filter element is inserted into the collection tube, and the installation is smooth. At the same time, there is a relay position when the filter element is taken out, so it is smooth to take out.

[0033] 2. The structure of the ultrafiltration centrifuge tube is simple, and the installation can be completed by using only one external connection process (connecting the ultrafiltration membrane with the filter element support plate).

[0034] 3. The filter element support plate and the inner wall of the concentrate collection tube are in interference fit, so that the filter element assembly and the filter element body are firmly sealed, and sealing can be achieved even in a high-speed centrifugal environment, thereby improving the recovery efficiency.

[0035] 4. The filter element assembly is suitable for existing centrifuge tube standards and is compatible with various brands of centrifuges, with good versatility;

[0036] 5. To assemble the filter element assembly, only 2 mold opening parts, 2 ultrafiltration membranes, and 2 sealing rings are required, which reduces costs.

[0037] Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments, or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. An ultrafiltration centrifuge tube for a centrifuge, characterized in that: It includes a shell and a filtering device installed in the shell, the shell includes a circular tubular concentrated liquid collection tube and a tube cover threadedly screwed thereon; the filtering device includes a filter element main body, the filter element main body is a blind tube structure, and two planes are symmetrically opened on both sides of its tail end, each of the two planes is provided with a rectangular ultrafiltration membrane hole, a semi-cylindrical filter element support plate is arranged on the outside of the rectangular ultrafiltration membrane hole, the filter element support plate is a semi-cylindrical plane side on one side of the ultrafiltration membrane hole, a rectangular boss is arranged on it, an ultrafiltration membrane is welded or glued on the boss, and a sealing ring is mounted around the rectangular boss.

2. The ultrafiltration centrifuge tube for a centrifuge according to claim 1, characterized in that: The filter element support plate is processed from a semi-cylinder, and a platform structure is provided in the middle of one side of the cylindrical surface of the semi-cylinder. A section of the semi-cylinder is retained at the front and rear ends respectively. The rear end surface of the rear semi-cylinder is flush with the tail end of the semi-cylinder, and a small platform is provided on the front side of the front semi-cylinder. A groove is provided on the small platform close to the front semi-cylinder, and a plurality of guide holes are provided in the groove. A plurality of guide grooves connected to the guide holes are provided on a rectangular boss provided on one side of the semi-cylinder plane.

3. The ultrafiltration centrifuge tube for a centrifuge according to claim 1, characterized in that: The sealing ring is higher than a rectangular boss arranged on one side of the semi-cylindrical plane of the filter element support plate, and is pressed tightly against the four peripheries of the rectangular ultrafiltration membrane hole on the plane of the tail end of the filter element body.

4. The ultrafiltration centrifuge tube for a centrifuge according to claim 1, characterized in that: An annular boss is arranged outside the opening end of the filter element body, and a venting groove is arranged on the annular boss.

5. The ultrafiltration centrifuge tube for a centrifuge according to claim 1, characterized in that: After assembly, the filter device is inserted into the concentrate collection tube, the semi-cylindrical surface on the filter element support plate is pressed against the inner wall of the concentrate collection tube, presenting a slightly positive pressure state, the tail end of the filter element body is flush with the tube opening of the concentrate collection tube, and the tube cover is screwed tightly on the concentrate collection tube.

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