Microfluidic chip bearing frame and detection equipment

By designing the structure of the support disc, fixed column, support strip and outer support ring, the fixed fan ring chip solves the problems of insufficient mechanical strength and position offset during splicing of microfluidic chips, and realizes stable fixation and efficient detection of the chip.

CN222174119UActive Publication Date: 2024-12-17SHENZHEN YHLO BIOTECH
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Patent Information

Application Number
CN202420774006.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-15
Publication Date
2024-12-17
Estimated Expiration
2034-04-15

AI Technical Summary

Technical Problem

The existing microfluidic chip splicing method has problems such as insufficient mechanical strength, resulting in chip disintegration, reduction of test items per unit area, and the chip position shifts when rotating at high speed, affecting the detection effect.

Method used

Design a bearing frame for a microfluidic chip, including a support disc, a fixed column, a support strip and an outer support ring, and fix the fan ring through the structure of the card slot and the limiting column to reduce interference with the driving device and prevent the chip from being deviated. and improve structural strength and connection firmness through the inner support ring.

Benefits of technology

The stable fixation and smooth rotation of multiple fan ring chips are achieved, reducing the risk of chip position deviation and ensuring the normal progress and efficiency of detection.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to a bearing frame of a micro-fluidic chip. The bearing frame comprises a supporting disc, fixing columns, supporting strips and an outer supporting ring. The supporting disc is provided with a supporting face in the thickness direction. The fixing column is connected to the middle of the supporting face of the supporting disc, a limiting convex rib is arranged on the peripheral face of the outer side of the fixing column, the limiting convex rib and the supporting disc are arranged in a spaced mode, and a clamping groove is defined by the limiting convex rib, the outer side of the fixing column and the supporting face; the outer supporting ring is fixed to the supporting disc through supporting strips, the other ends of the supporting strips are connected with the outer supporting ring, the outer supporting ring surrounds the supporting disc in the circumferential direction of the supporting disc, the outer supporting ring and the outer side circumferential face of the supporting disc are arranged at intervals, and a plurality of limiting columns are arranged on the supporting ring at intervals in the circumferential direction of the supporting ring; when the bearing frame bears a plurality of sector-ring-shaped chips, the clamping grooves are used for clamping inner rings of the sector-ring-shaped chips, and the limiting columns are used for being inserted into limiting holes in outer rings of the sector-ring-shaped chips so as to limit movement of the sector-ring-shaped chips.
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Description

Technical Field

[0001] The present invention relates to the field of medical technology, and in particular to a supporting frame and detection equipment for a microfluidic chip. Background Art

[0002] Microfluidic chips are microanalysis systems that integrate sample pretreatment, mixing, reaction, separation and detection into one or more chips. They can replace traditional laboratory work. Microfluidic chips require less sample, are easy to operate, and can accurately complete the entire process from sample preparation to result display in a relatively short period of time, effectively overcoming the experimental errors caused by manual operations in traditional laboratory work. Therefore, microfluidic chips have been increasingly used in chemical analysis, DNA sequencing, protein analysis, single cell analysis, single molecule analysis, food safety, environmental testing and drug screening.

[0003] In the actual testing of samples in hospitals, it often happens that a patient needs to be tested for multiple different items, or that different hospitals may perform different tests for the same symptom.

[0004] Compared with traditional detection methods, the reagents of microfluidic technology are pre-sealed in microfluidic chips. Conventional disc-shaped chips usually have a fixed combination of pre-sealed reagent items for the necessity and convenience of large-scale production. This inevitably leads to the situation that the chip disc cannot be fully adapted to the actual use needs. There will be a patient who needs to test multiple chip discs, which increases the patient's waiting time; at the same time, the excess pre-sealed reagents are not used, which increases the cost and the patient does not receive an effective diagnosis.

[0005] In order to achieve the most reasonable balance point, which can meet the actual needs of patients and the efficiency of large-scale production of manufacturers, different sector chips are needed. Each chip is pre-installed with only a few different projects. According to the needs of different patients, different sector chips are spliced ​​on demand to fully adapt to the diagnosis plan of the patient's personalized needs. For the needs of a single small number of projects, sector chip splicing can also be achieved on the same chip, and multiple patients can be measured at the same time, making the average waiting time for a single person shorter.

[0006] There are two main ways of splicing chips. The first is to splice multiple chips together, and the second is to splice multiple chips together with an external frame. In the first splicing method, when multiple chips are spliced ​​together, a certain overall mechanical strength is required to ensure that they will not fall apart during normal operation. Therefore, some buckles, concave-convex grooves, mortise and tenon structures, etc. that play a role in fixing each other will be designed on the chip. However, these additional designs occupy the effective design space on the chip, resulting in fewer test items per unit area. The second splicing method, that is, the splicing method of the chip external frame, usually adopts a chip-on-lower frame structure to form a three-layer structure of motor tray, splicing frame, and chip. Although this architectural form solves the problem of effective use of space and thickening of self-splicing, at the same time, since the motor inside the instrument also supports the chip from below to generate centrifugal rotation force, on the one hand, the frame may interfere with the motor, and on the other hand, when rotating at high speed, the risk of position displacement of the chip is relatively high, which in turn affects the normal progress and detection effect of the test.

[0007] BACKGROUND OF THE PRESENT APPLICATION The above information disclosed is only for understanding the background of the concept of the present application and may contain information that does not constitute the prior art. Summary of the invention

[0008] Based on this, it is necessary to provide a supporting frame and detection equipment for a microfluidic chip to address the above problems.

[0009] A microfluidic chip carrying frame, used for carrying a plurality of fan-shaped ring chips, the microfluidic chip carrying frame comprising:

[0010] A support plate, wherein the support plate has a support surface along a thickness direction;

[0011] A fixing column, the fixing column is connected to the middle part of the supporting surface of the supporting plate, a limiting convex rib is provided on the outer peripheral surface of the fixing column, the limiting convex rib is spaced apart from the supporting plate, and the limiting convex rib, the outer side of the fixing column and the supporting surface are surrounded to form a slot;

[0012] A support bar and an outer support ring, wherein the outer support ring is fixed to the support disk through the support bar, the other end of the support bar is connected to the outer support ring, the outer support ring surrounds the support disk along the circumference of the support disk, and the outer support ring is spaced apart from the outer circumference of the support disk, and a plurality of limit posts are provided on the support ring, and the plurality of limit posts are spaced apart along the circumference of the support ring;

[0013] Among them, when the supporting frame carries multiple fan-shaped chips, the card slot is used to clamp the inner ring of the fan-shaped chip, and the limiting column is used to insert into the limiting hole on the outer ring of the fan-shaped chip to limit the movement of the fan-shaped chip.

[0014] The supporting frame of the microfluidic chip mentioned above in the present application can at least achieve the following beneficial effects: multiple fan-shaped ring chips can be carried on the supporting frame, and the inner rings of the multiple fan-shaped ring chips can be inserted into the slots on the fixed columns, and the limiting holes on the outer rings of the multiple fan-shaped ring chips can be sleeved on the limiting columns on the outer support ring, so that the supporting frame limits the movement of the multiple fan-shaped ring chips. When in use, the supporting frame can be turned upside down to connect with the tray of the driving device, and the multiple fan-shaped ring chips are clamped between the tray and the supporting frame, and then the supporting frame and the multiple fan-shaped ring chips thereon can be rotated under the drive of the driving device. Compared with the traditional solution, the driving device and the supporting frame of the present application are farther apart, which can reduce the risk of mutual interference between the two, and the fan-shaped ring chip of the present application is not located above the frame, but is clamped between the tray and the supporting frame, which has a better fixing effect, can prevent the chip from being displaced, and ensure the smooth progress of subsequent detection.

[0015] In one embodiment, the support frame of the microfluidic chip further includes an inner support ring, which is fixed to the support bar and is located between the outer support ring and the support plate. Such a structural setting means that there are more hollow areas between the outer support ring and the inner support ring, and between the inner support ring and the support plate, which can reduce the weight and manufacturing cost of the support frame. Moreover, by adding an inner support ring between the outer support ring and the support plate, the structural strength of the support frame can be ensured to prevent the support bar from deforming. Moreover, the inner support ring can also have a certain supporting effect on the middle part of the chip, making the connection between the chip and the support frame more secure.

[0016] In one embodiment, the limiting convex rib extends in a ring shape along the circumference of the fixing column. If the limiting convex rib is in a ring shape, the clamping groove is also distributed around the circumference of the fixing column, which can ensure that the inner rings of multiple fan-shaped chips have a clamping effect and ensure that the chips are firmly fixed.

[0017] In one embodiment, the number of the support bars is set to be multiple, and the multiple support bars are connected to the outer peripheral surface of the support plate and are evenly spaced along the circumference of the support plate. Such a structural setting can further improve the structural strength of the load-bearing frame and prevent deformation.

[0018] In one embodiment, the outer support ring is also provided with a plurality of partition protrusions, and the plurality of partition protrusions are evenly spaced along the circumference of the outer support ring to separate a plurality of loading areas, and one loading area is used to load one fan-shaped ring chip. The plurality of partition protrusions is equivalent to evenly dividing the space on the bearing frame, so that the bearing area of ​​each fan-shaped ring chip is the same, and the partition protrusions can also play a role in positioning and guiding. When placing the plurality of fan-shaped ring chips on the bearing frame, each fan-shaped ring chip needs to be placed between two adjacent partition protrusions. At this time, the limit column on the outer support ring can just align with the limit hole on the chip and then be inserted into the limit hole.

[0019] In one embodiment, the cross-sectional profile of the separation protrusion is triangular and one corner thereof is aligned with the center of the support plate.

[0020] In one embodiment, the outer support ring is arranged concentrically with the support disk.

[0021] In one embodiment, a plurality of equally spaced limiting posts are provided between any two adjacent separation protrusions in the circumferential direction of the outer support ring. The equally spaced distribution of the plurality of limiting posts can allow the chip to be uniformly stressed.

[0022] In one of the embodiments, at least one of the separation protrusions is provided with a positioning notch, and the positioning notch is used to cooperate with a positioning protrusion on a detection device to perform origin positioning on the supporting frame and the microfluidic chip on the supporting frame.

[0023] In one embodiment, the limiting column is inclined toward the support plate. The inclined limiting column can cooperate with the slot on the support plate to clamp the chip between the limiting column and the slot to ensure that the chip does not fall.

[0024] In one of the embodiments, the limiting column is arranged at an acute angle to the supporting surface of the supporting plate.

[0025] In one of the embodiments, one side of the outer support ring is flush with the support surface of the support plate.

[0026] In one of the embodiments, a positioning notch is provided on the outer peripheral surface of the outer support ring, and the positioning notch is used to cooperate with a positioning protrusion on a detection device to perform origin positioning on the supporting frame and the microfluidic chip on the supporting frame.

[0027] In one embodiment, the fixing column is provided with a mounting hole along its axial direction, and the mounting hole is used for direct or indirect connection with a driving device.

[0028] The present application also provides a detection device, which includes a driving device and a supporting frame of the microfluidic chip as described in any of the above embodiments, wherein the driving device is used to drive the supporting frame of the microfluidic chip to rotate.

[0029] Since the above-mentioned detection device includes the supporting frame of the microfluidic chip described in any of the above-mentioned embodiments, the detection device also includes at least the following beneficial effects: a plurality of fan-shaped chips can be carried on the supporting frame, and the inner rings of the plurality of fan-shaped chips can be inserted into the slots on the fixing columns, and the limiting holes on the outer rings of the plurality of fan-shaped chips can be sleeved on the limiting columns on the outer support ring, so that the supporting frame limits the movement of the plurality of fan-shaped chips. When in use, the supporting frame can be turned upside down to connect with the tray of the driving device, and the plurality of fan-shaped chips are clamped between the tray and the supporting frame, and then the supporting frame and the plurality of fan-shaped chips thereon can be rotated under the drive of the driving device. Compared with the traditional scheme, the driving device of the present application is farther away from the supporting frame, which can reduce the risk of mutual interference between the two, and the fan-shaped chip of the present application is not located above the frame, but is clamped between the tray and the supporting frame, so the fixing effect is better, which can prevent the chip from being displaced, and ensure the smooth progress of subsequent detection.

[0030] In one embodiment, the driving device includes a driving motor and a tray connected to the output shaft of the driving motor, the tray is used to press the plurality of fan-shaped chips onto the supporting frame, and the driving device is used to drive the supporting frame of the microfluidic chip to rotate.

[0031] In one embodiment, the driving device includes a driving motor and a tray, the tray is used to press the plurality of fan-shaped chips onto the supporting frame, the output shaft of the driving motor is passed through the tray to be detachably connected to the supporting plate, and the driving device is used to drive the supporting frame of the microfluidic chip to rotate.

[0032] In one embodiment, the detection equipment also includes a mounting part, the driving device includes a driving motor and a tray, the tray is used to press the plurality of fan-shaped chips onto the supporting frame, the mounting part is passed through the supporting plate to be detachably connected to the tray or the output shaft of the driving motor, and the driving device is used to drive the supporting frame of the microfluidic chip to rotate. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the conventional technology, the drawings required for use in the embodiments or the conventional technology descriptions are briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0034] Figure 1 A structural stereogram of a load-bearing frame provided in one embodiment of the present invention.

[0035] Figure 2 Another structural stereoscopic diagram of a load-bearing frame provided in yet another embodiment of the present invention.

[0036] Figure 3 A schematic plan view of a load-bearing frame provided in one embodiment of the present invention.

[0037] Figure 4 Another structural stereoscopic diagram of a carrying frame provided in yet another embodiment of the present invention, on which a chip is carried.

[0038] Figure 5 A schematic structural diagram of a driving device and a supporting frame provided in one embodiment of the present invention.

[0039] Reference numerals:

[0040] 10. Carrying frame; 20. Chip; 21. Limiting hole; 22. Inner ring; 23. Outer ring; 30. Driving device; 31. Driving motor; 311. Output shaft; 32. Tray; 100. Support plate; 110. Support surface; 120. Mounting hole; 200. Fixing column; 210. Limiting rib; 220. Slot; 300. Support bar; 400. Outer support ring; 410. Limiting column; 420. Partitioning protrusion; 430. Positioning notch; 500. Inner support ring. DETAILED DESCRIPTION

[0041] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present invention, so the present invention is not limited by the specific embodiments disclosed below.

[0042] See also Figure 1 and Figure 2In some embodiments, the present application provides a support frame 10 for a microfluidic chip 20, which can be used to support multiple fan-shaped chips 20. The support frame 10 for the microfluidic chip 20 includes: a support plate 100, a fixed column 200, a support bar 300 and an outer support ring 400. The support plate 100 has a support surface 110 along the thickness direction; the fixed column 200 is connected to the middle of the support surface 110 of the support plate 100, and the outer peripheral surface of the fixed column 200 is provided with a limiting rib 210, and the limiting rib 210 is spaced from the support plate 100. The limiting rib 210, the outer side of the fixed column 200 and the support surface 110 are surrounded to form a slot 220; the outer support ring 400 is fixed to the support plate 100 through the support bar 300, and the other end of the support bar 300 is connected to the outer support ring 400. The ring 400 surrounds the support disk 100 along the circumference of the support disk 100, and the outer support ring 400 is spaced apart from the outer circumference of the support disk 100. A plurality of limit posts 410 are provided on the support ring, and a plurality of the limit posts 410 are spaced apart along the circumference of the support ring; wherein, when the supporting frame 10 carries a plurality of fan-ring chips 20, the card slot 220 is used to clamp the inner ring 22 of the fan-ring chip 20, and the limit post 410 is used to insert into the limit hole 21 on the outer ring 23 of the fan-ring chip 20 to limit the movement of the fan-ring chip 20.

[0043] The carrier frame 10 of the microfluidic chip 20 described above in the present application can at least achieve the following beneficial effects: the carrier frame 10 can carry multiple fan-shaped chips 20, and the inner rings 22 of the multiple fan-shaped chips 20 can be inserted into the slots 220 on the fixed column 200, and the limiting holes 21 on the outer rings 23 of the multiple fan-shaped chips 20 can be sleeved on the limiting columns 410 on the outer support ring 400, so that the carrier frame 10 limits the movement of the multiple fan-shaped chips 20. When in use, the carrier frame 10 can be turned upside down to connect with the tray 32 of the driving device 30, and the multiple fan-shaped chips 20 are clamped between the tray 32 and the carrier frame 10, and then the carrier frame 10 and the multiple fan-shaped chips 20 thereon can be rotated under the drive of the driving device 30. Compared with traditional solutions, the distance between the driving device 30 and the supporting frame 10 of the present application is farther, which can reduce the risk of mutual interference between the two. In addition, the fan-shaped chip 20 of the present application is not located above the frame, but is clamped between the tray 32 and the supporting frame 10, which has a better fixing effect and can prevent the chip 20 from being displaced, thereby ensuring the smooth progress of subsequent inspections.

[0044] In some embodiments, the carrier frame 10 of the microfluidic chip 20 further includes an inner support ring 500, which is fixed to the support bar 300 and is located between the outer support ring 400 and the support plate 100. Such a structural setting means that there are more hollow areas between the outer support ring 400 and the inner support ring 500, and between the inner support ring 500 and the support plate 100, which can reduce the weight and manufacturing cost of the carrier frame 10. Moreover, by adding the inner support ring 500 between the outer support ring 400 and the support plate 100, the structural strength of the carrier frame 10 can be ensured, and the deformation of the support bar 300 can be prevented. Moreover, the inner support ring 500 can also have a certain supporting effect on the middle part of the chip 20, so that the connection between the chip 20 and the carrier frame 10 is more secure.

[0045] In some embodiments, the limiting rib 210 is annularly extending along the circumference of the fixing column 200. The limiting rib 210 is annular, and the clamping groove 220 is also distributed around the circumference of the fixing column 200, which can ensure that the inner rings 22 of multiple fan-shaped chips 20 have a clamping effect, ensuring that the chips 20 are firmly fixed.

[0046] In some embodiments, the number of the support bars 300 is set to be multiple, and the multiple support bars 300 are connected to the outer peripheral surface of the support plate 100 and are evenly spaced along the circumference of the support plate 100. Such a structural setting can further improve the structural strength of the load-bearing frame 10 and prevent deformation.

[0047] In some of the embodiments, the outer support ring 400 is further provided with a plurality of partition protrusions 420, and the plurality of partition protrusions 420 are evenly spaced along the circumference of the outer support ring 400 to separate a plurality of loading areas, and one loading area is used to load one of the fan-shaped ring chips 20. The plurality of partition protrusions 420 is equivalent to evenly dividing the space on the bearing frame 10, so that the bearing area of ​​each fan-shaped ring chip 20 is the same, and the partition protrusions 420 can also play a role in positioning and guiding. When placing the plurality of fan-shaped ring chips 20 on the bearing frame 10, each fan-shaped ring chip 20 needs to be placed between two adjacent partition protrusions 420. At this time, the limiting column 410 on the outer support ring 400 can just align with the limiting hole 21 on the chip 20 and then be inserted into the limiting hole 21.

[0048] In some embodiments, the cross-sectional profile of the separation protrusion 420 is triangular and one corner thereof is aligned with the center of the support plate 100 .

[0049] In some embodiments, the outer support ring 400 is disposed concentrically with the support plate 100 .

[0050] In some embodiments, a plurality of equally spaced limiting posts 410 are disposed between any two adjacent separation protrusions 420 in the circumferential direction of the outer support ring 400. The equally spaced distribution of the plurality of limiting posts 410 allows the chip 20 constrained by the limiting posts to be uniformly stressed.

[0051] In some embodiments, at least one of the separation protrusions 420 is provided with a positioning notch 430 , and the positioning notch 430 is used to cooperate with a positioning protrusion on a detection device to perform origin positioning on the supporting frame 10 and the microfluidic chip 20 on the supporting frame 10 .

[0052] In some embodiments, the limiting column 410 is tilted toward the support plate 100. The tilted limiting column 410 can cooperate with the slot 220 on the support plate 100 to clamp the chip 20 between the limiting column 410 and the slot 220 to ensure that the chip 20 does not fall.

[0053] In some embodiments, the limiting post 410 is disposed at an acute angle to the supporting surface 110 of the supporting plate 100 .

[0054] In some embodiments, one side of the outer support ring 400 is flush with the support surface 110 of the support plate 100 .

[0055] In some embodiments, a positioning notch 430 is formed on the outer circumference of the outer support ring 400 , and the positioning notch 430 is used to cooperate with a positioning protrusion on a detection device to perform origin positioning on the supporting frame 10 and the microfluidic chip 20 on the supporting frame 10 .

[0056] In some embodiments, the fixing column 200 is provided with a mounting hole 120 along its axial direction, and the mounting hole 120 is used for direct or indirect connection with the driving device 30 .

[0057] The present application also provides a detection device, which includes a driving device 30 and a supporting frame 10 of the microfluidic chip 20 as described in any of the above embodiments, wherein the driving device 30 is used to drive the supporting frame 10 of the microfluidic chip 20 to rotate.

[0058] The above-mentioned detection device, because it includes the carrier frame 10 of the microfluidic chip 20 described in any of the above-mentioned embodiments, the detection device also includes at least the following beneficial effects: the carrier frame 10 can carry multiple fan-shaped chips 20, and the inner rings 22 of the multiple fan-shaped chips 20 can be snapped into the slots 220 on the fixed column 200, and the limiting holes 21 on the outer rings 23 of the multiple fan-shaped chips 20 can be sleeved on the limiting columns 410 on the outer support ring 400, so that the carrier frame 10 limits the movement of the multiple fan-shaped chips 20. When in use, the carrier frame 10 can be turned upside down to connect with the tray 32 of the driving device 30, and the multiple fan-shaped chips 20 are clamped between the tray 32 and the carrier frame 10, and then the carrier frame 10 and the multiple fan-shaped chips 20 thereon can be rotated under the drive of the driving device 30. Compared with traditional solutions, the distance between the driving device 30 and the supporting frame 10 of the present application is farther, which can reduce the risk of mutual interference between the two. In addition, the fan-shaped chip 20 of the present application is not located above the frame, but is clamped between the tray 32 and the supporting frame 10, which has a better fixing effect and can prevent the chip 20 from being displaced, thereby ensuring the smooth progress of subsequent inspections.

[0059] In some embodiments, the driving device 30 includes a driving motor 31 and a tray 32 connected to the output shaft 311 of the driving motor 31, the tray 32 is used to press the multiple fan-ring chips 20 onto the supporting frame 10, and the driving device 30 is used to drive the supporting frame 10 of the microfluidic chip 20 to rotate.

[0060] In some embodiments, the driving device 30 includes a driving motor 31 and a tray 32, the tray 32 is used to press the multiple fan-ring chips 20 onto the supporting frame 10, the output shaft 311 of the driving motor 31 is passed through the tray 32 to be detachably connected to the support plate 100, and the driving device 30 is used to drive the supporting frame 10 of the microfluidic chip 20 to rotate.

[0061] In some embodiments, the detection device also includes a mounting part, the driving device 30 includes a driving motor 31 and a tray 32, the tray 32 is used to press the multiple fan-ring chips 20 onto the supporting frame 10, the mounting part is passed through the support plate 100 to be detachably connected to the tray 32 or the output shaft 311 of the driving motor 31, and the driving device 30 is used to drive the supporting frame 10 of the microfluidic chip 20 to rotate.

[0062] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0063] The above-described embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be construed as limiting the scope of the patent application. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent application shall be subject to the attached claims.

[0064] In the description of the present application, it should be understood that if the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. appear, the orientation or position relationship indicated by these terms is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing the present application and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application.

[0065] In addition, if the terms "first" or "second" appear, these terms are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of the features. In the description of this application, if the term "plurality" appears, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0066] In this application, unless otherwise clearly specified and limited, if the terms "installed", "connected", "connected", "fixed" and the like appear, these terms should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integrated connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to the specific circumstances.

[0067] In the present application, unless otherwise clearly specified and limited, if there is a description that a first feature is "above" or "below" a second feature, etc., or similar descriptions appear, it may mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediate medium. Moreover, the first feature being "above", "above" and "above" the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being "below", "below" and "below" the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0068] It should be noted that if an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be a central element. If an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. If any, the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in this application are for illustrative purposes only and do not represent the only implementation method.

[0069] In the description of this specification, the description of reference terms "one embodiment", "other implementation methods", etc. means that the specific features, structures, materials or features described in conjunction with the embodiment or example are included in at least one embodiment or example of the present application. In this specification, the schematic descriptions of the above terms do not necessarily refer to the same embodiment or example. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by technicians in the technical field of the present application. The terms used herein in the specification of the present application are only for the purpose of describing specific embodiments and are not intended to limit the present application.

Claims

1. A microfluidic chip carrier frame, used to carry multiple fan-shaped chips, characterized in that: The supporting frame of the microfluidic chip comprises: A support plate, wherein the support plate has a support surface along a thickness direction; A fixing column, the fixing column is connected to the middle part of the supporting surface of the supporting plate, a limiting convex rib is provided on the outer peripheral surface of the fixing column, the limiting convex rib is spaced apart from the supporting plate, and the limiting convex rib, the outer side of the fixing column and the supporting surface are surrounded to form a slot; A support bar and an outer support ring, wherein the outer support ring is fixed to the support disk through the support bar, the other end of the support bar is connected to the outer support ring, the outer support ring surrounds the support disk along the circumference of the support disk, and the outer support ring is spaced apart from the outer circumference of the support disk, and a plurality of limit posts are provided on the support ring, and the plurality of limit posts are spaced apart along the circumference of the support ring; Among them, when the supporting frame carries multiple fan-shaped chips, the card slot is used to clamp the inner ring of the fan-shaped chip, and the limiting column is used to insert into the limiting hole on the outer ring of the fan-shaped chip to limit the movement of the fan-shaped chip.

2. The microfluidic chip support frame according to claim 1, characterized in that: The support frame of the microfluidic chip further comprises an inner support ring, which is fixed to the support bar and is located between the outer support ring and the support plate; And / or, the limiting rib extends in a ring shape along the circumference of the fixing column.

3. The microfluidic chip support frame according to claim 1, characterized in that: The number of the support bars is set to be multiple, and the multiple support bars are connected to the outer peripheral surface of the support plate and are evenly spaced along the circumference of the support plate.

4. The microfluidic chip support frame according to claim 1, characterized in that: The outer support ring is also provided with a plurality of partition protrusions, which are evenly spaced along the circumference of the outer support ring to separate a plurality of loading areas, and one loading area is used to load one of the fan-shaped ring chips.

5. The microfluidic chip support frame according to claim 4, characterized in that: The cross-sectional profile of the separation protrusion is triangular and one corner thereof is aligned with the center of the support plate; And / or, the outer support ring is arranged concentrically with the support disk; And / or, on the circumference of the outer support ring, a plurality of equally spaced limiting columns are provided between any two adjacent separation protrusions.

6. The microfluidic chip support frame according to claim 4, characterized in that: A positioning notch is formed on at least one of the separation protrusions, and the positioning notch is used to cooperate with a positioning protrusion on a detection device to perform origin positioning on the supporting frame and the microfluidic chip on the supporting frame.

7. The microfluidic chip support frame according to claim 1, characterized in that: The outer peripheral surface of the outer support ring is provided with a positioning notch, and the positioning notch is used to cooperate with the positioning protrusion on the detection device to perform origin positioning on the carrying frame and the microfluidic chip on the carrying frame; And / or, the limiting column is arranged to be inclined toward the direction close to the supporting plate; And / or, the limiting column and the supporting surface of the supporting plate are arranged at an acute angle; And / or, one side of the outer support ring is flush with the support surface of the support plate.

8. The microfluidic chip support frame according to claim 1, characterized in that: The fixing column is provided with a mounting hole along its axial direction, and the mounting hole is used for direct or indirect connection with a driving device.

9. A detection device, characterized in that: The invention comprises a driving device and a supporting frame of the microfluidic chip according to any one of claims 1 to 8, wherein the driving device is used to drive the supporting frame of the microfluidic chip to rotate.

10. The detection device according to claim 9, characterized in that: The driving device comprises a driving motor and a tray connected to the output shaft of the driving motor, the tray is used to press the plurality of fan-shaped chips onto the supporting frame, and the driving device is used to drive the supporting frame of the microfluidic chip to rotate; Alternatively, the driving device comprises a driving motor and a tray, the tray is used to press the plurality of fan-shaped chips onto the supporting frame, the output shaft of the driving motor is passed through the tray to be detachably connected to the supporting plate, and the driving device is used to drive the supporting frame of the microfluidic chip to rotate; Alternatively, the detection device also includes a mounting part, the driving device includes a driving motor and a tray, the tray is used to press the plurality of fan-ring chips onto the supporting frame, the mounting part is passed through the supporting plate to be detachably connected to the tray or the output shaft of the driving motor, and the driving device is used to drive the supporting frame of the microfluidic chip to rotate.