Bottle cleaning assembly

Abstract

The utility model discloses a cleaning bottle assembly which comprises a waste liquid bottle, a cleaning bottle, a sliding support and a mounting support. The waste liquid bottle and the cleaning bottle are arranged in the sliding bracket; the mounting bracket comprises a limiting part, a slideway and a limiting structure; the sliding bracket is slidably connected with the slideway; the limiting part is fixedly connected with the slideway; one end of the limiting structure is fixedly connected with the limiting part, and the other end is detachably connected with the sliding bracket. The exosome enrichment device has the beneficial effects that the mounting bracket is mounted in the automatic exosome enrichment device; when the waste liquid bottle and the cleaning bottle need to be replaced, the sliding bracket is driven to slide along the slide way, and the waste liquid bottle and the cleaning bottle are driven to extend out of the automatic exosome enrichment equipment; after replacement is completed, the sliding support is driven to enter the automatic exosome enrichment equipment along a waste liquid bottle and cleaning bottle slide way; after the sliding bracket is reset, the position of the sliding bracket is limited by the limiting structure, so that the waste liquid bottle and the cleaning bottle are prevented from deviating, and the influence on the operation of other parts in the automatic exosome enrichment equipment is prevented.

Description

Technical Field

[0001] The utility model belongs to the technical field of medical equipment, and in particular relates to a cleaning bottle assembly. Background Art

[0002] Exosomes refer to small membrane vesicles (30-150nm) containing complex RNA and proteins. Nowadays, they specifically refer to discoid vesicles with a diameter of 40-100nm. In 1983, exosomes were first discovered in sheep reticulocytes, and Johnstone named them "exosomes" in 1987. A variety of cells can secrete exosomes under normal and pathological conditions. They are mainly derived from multivesicular bodies formed by the invagination of intracellular lysosomal microparticles, and are released into the extracellular matrix after the multivesicular outer membrane fuses with the cell membrane.

[0003] Exosomes are considered to be specifically secreted membrane vesicles that participate in intercellular communication, and there is growing interest in studying exosomes, both to investigate their functions and to understand how they can be used in the development of minimally invasive diagnostics.

[0004] Neurodegenerative diseases are caused by the loss of neurons and / or their myelin sheaths, which worsen over time and cause functional disorders. Such as Alzheimer's disease (AD), Parkinson's disease (PD), and prion disease. At present, the clear clinical diagnosis of neurodegenerative diseases relies on PET (positron emission tomography), and when pathological changes occur, the disease often develops to an untreatable and irreversible stage. Or the detection of biomarkers through cerebrospinal fluid is highly traumatic and risky, and it is difficult to promote. With the in-depth study of exosomes, it was found that neurogenic exosomes in the blood can be used as samples to detect relevant indicators of neurodegenerative diseases, which can greatly advance the diagnosis of such diseases; and compared with cerebrospinal fluid, this type of sample has stronger compliance for subjects.

[0005] In the process of automated exosome enrichment, a centrifuge is required for centrifugation, and after the solution is centrifuged, a cleaning solution is required to clean the centrifuge rotor and collect the waste liquid after cleaning. In the process again, the cleaning bottle for storing the cleaning solution and the waste liquid bottle for collecting the waste liquid need to be placed inside the automated exosome enrichment device. Since the automated exosome enrichment device is small in size, its internal cavity is even narrower, making it inconvenient to replace the cleaning bottle and the waste liquid bottle.

[0006] Aiming at the above problems, the utility model provides a cleaning bottle assembly. Utility Model Content

[0007] In order to overcome the problems raised in the background technology, the utility model provides a cleaning bottle assembly.

[0008] A cleaning bottle assembly comprises a waste liquid bottle, a cleaning bottle, a sliding bracket and a mounting bracket; the waste liquid bottle and the cleaning bottle are both arranged inside the sliding bracket; the mounting bracket comprises a limiting portion, a slide and a limiting structure; the sliding bracket is slidably connected to the slide; the limiting portion is fixedly connected to the slide; one end of the limiting structure is fixedly connected to the limiting portion, and the other end is detachably connected to the sliding bracket.

[0009] Furthermore, the limiting structure is a magnetic attraction structure; the sliding bracket is made of one or more of iron, cobalt, and nickel.

[0010] Furthermore, a partition is provided inside the sliding bracket; the partition divides the interior of the sliding bracket into two parts.

[0011] Furthermore, a sliding block is provided at the bottom of the sliding bracket; one end of the sliding block is fixedly connected to the sliding bracket, and the other end of the sliding block is slidably connected to the slideway.

[0012] Furthermore, a first connection port is provided on the top of the waste liquid bottle; the first connection port is connected to the interior of the waste liquid bottle.

[0013] Furthermore, a first sensor is also provided on the top of the waste liquid bottle.

[0014] Furthermore, a second connection port is provided on the top of the cleaning bottle; the second connection port is communicated with the interior of the cleaning bottle; and a connection tube is provided at one end of the second connection port inserted into the cleaning bottle.

[0015] Furthermore, one end of the connecting tube away from the second connecting port contacts the inner bottom surface of the cleaning bottle.

[0016] Furthermore, a second sensor is provided on the top of the cleaning bottle.

[0017] Furthermore, the limiting portion is arranged perpendicular to the slideway.

[0018] The beneficial effects of the utility model are as follows: the mounting bracket is mounted inside the automated exosome enrichment device; the sliding bracket drives the waste liquid bottle and the cleaning bottle to move along the slide; when the waste liquid bottle and the cleaning bottle need to be replaced, the sliding bracket is driven to slide along the slide, driving the waste liquid bottle and the cleaning bottle to extend out of the automated exosome enrichment device; after the replacement is completed, the sliding bracket is driven to drive the waste liquid bottle and the cleaning bottle along the slide into the interior of the automated exosome enrichment device, so that the waste liquid bottle and the cleaning bottle can be replaced conveniently and quickly; when the sliding bracket is reset, the limiting structure limits the position of the sliding bracket to prevent the waste liquid bottle and the cleaning bottle from being displaced and affecting the operation of other components in the automated exosome enrichment device. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a structural schematic diagram of a cleaning bottle assembly for implementing the utility model;

[0020] Figure 2 It is a side view of a cleaning bottle assembly for implementing the utility model;

[0021] Figure 3 A top view of a cleaning bottle assembly for implementing the utility model;

[0022] Figure 4 for Figure 3 AA section view;

[0023] Figure 5 It is a structural schematic diagram of a sliding bracket for implementing the utility model;

[0024] Figure 6 It is a structural schematic diagram of a mounting bracket for implementing the utility model;

[0025] In the figure, 1. waste liquid bottle; 2. cleaning bottle; 3. sliding bracket; 4. mounting bracket; 11. first bottle body; 12. first sensor; 13. first connection port; 21. second bottle body; 22. second sensor; 23. second connection port; 24. connecting pipe; 31. slider; 32. partition; 41. limit part; 42. slideway; 43. magnetic attraction structure. DETAILED DESCRIPTION

[0026] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. The utility model can also be implemented or applied through other different specific implementation methods. In the absence of conflict, the following embodiments and features in the embodiments can be combined with each other. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0027] In the description of the present invention, it should be understood that the terms "upper", "lower", "front", "back", "top", "bottom", "inside", "outside", etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0028] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present utility model, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0029] like Figure 1-6 A cleaning bottle 2 assembly shown includes a waste liquid bottle 1, a cleaning bottle 2, a sliding bracket 3 and a mounting bracket 4; the waste liquid bottle 1 and the cleaning bottle 2 are both arranged inside the sliding bracket 3; the mounting bracket 4 is installed inside the automated exosome enrichment device;

[0030] The mounting bracket 4 includes a limiting portion 41, a slide 42 and a limiting structure; the sliding bracket 3 is slidably connected to the slide 42, and the sliding bracket 3 drives the waste liquid bottle 1 and the cleaning bottle 2 to move along the slide 42; the limiting portion 41 is fixedly connected to the slide 42; one end of the limiting structure is fixedly connected to the limiting portion 41, and the other end is detachably connected to the sliding bracket 3.

[0031] When the waste liquid bottle 1 and the cleaning bottle 2 need to be replaced, the sliding bracket 3 is driven to slide along the slideway 42, driving the waste liquid bottle 1 and the cleaning bottle 2 to extend out of the automated exosome enrichment device; after the replacement is completed, the sliding bracket 3 is driven to drive along the slideway 42 of the waste liquid bottle 1 and the cleaning bottle 2 to enter the interior of the automated exosome enrichment device, so as to conveniently and quickly replace the waste liquid bottle 1 and the cleaning bottle 2. When the sliding bracket 3 is reset, the limiting structure limits the position of the sliding bracket 3 to prevent the waste liquid bottle 1 and the cleaning bottle 2 from being offset and affecting the operation of other components in the automated exosome enrichment device.

[0032] Specifically, the limiting portion 41 is vertically arranged to the slideway 42 , and when the sliding bracket 3 is reset, the side wall of the sliding bracket 3 is in close contact with the limiting portion 41 .

[0033] In the exemplary embodiment of the present application, the limiting structure is a magnetic structure 43; the sliding bracket 3 is made of one or more of iron, cobalt, and nickel. When the sliding bracket 3 is reset, the magnetic force can be applied to limit the position of the sliding bracket 3. When the waste liquid bottle 1 and the cleaning bottle 2 need to be replaced, the sliding bracket 3 is pulled outward. When the pulling force provided to the sliding bracket 3 is greater than the magnetic force of the magnetic structure 43, the sliding bracket 3 can be pulled out of the automated exosome enrichment device, and the sliding bracket 3 drives the waste liquid bottle 1 and the cleaning bottle 2 to extend out of the automated exosome enrichment device.

[0034] Preferably, a handle is provided at one end of the sliding bracket 3 away from the limiting portion 41 .

[0035] The magnetic structure 43 makes the process of replacing the waste liquid bottle 1 and the cleaning bottle 2 more convenient. If other structures are used to limit the position of the sliding bracket 3, the locking of the sliding bracket 3 by the limiting structure must be released before the sliding bracket 3 can be pulled.

[0036] In other embodiments of the present application, an electromagnetic pin is used to lock the position of the sliding bracket 3. The electromagnetic pin is arranged inside the limiting portion 41; the axial direction of the electromagnetic pin is perpendicular to the direction of the slide 42. A locking structure is provided on the side wall of the sliding bracket 3; a through hole adapted to the electromagnetic pin is provided inside the locking structure. When the sliding bracket 3 is reset, the electromagnetic pin is inserted into the through hole to limit the position of the sliding bracket 3. When the waste liquid bottle 1 and the cleaning bottle 2 need to be replaced, the electromagnetic pin retracts and the electromagnetic pin is disengaged from the through hole, at which time the sliding bracket 3 can be pulled out of the automated exosome enrichment device along the slide 42.

[0037] like Figure 5 As shown, a partition 32 is provided inside the sliding bracket 3; the partition 32 divides the inside of the sliding bracket 3 into two storage spaces. The two storage spaces are respectively adapted to the waste liquid bottle 1 and the cleaning bottle 2, and the waste liquid bottle 1 and the cleaning bottle 2 are fixed inside the sliding bracket 3 to prevent the waste liquid bottle 1 and the cleaning bottle 2 from detaching from the sliding bracket 3.

[0038] like Figure 2 As shown, a slider 31 is provided at the bottom of the sliding bracket 3; one end of the slider 31 is fixedly connected to the sliding bracket 3, and the other end is slidably connected to the slideway 42. The purpose of the slider 31 is to limit the sliding bracket 3 on the slideway 42 to ensure that the sliding bracket 3 can move along the slideway 42.

[0039] like Figure 2 , 3 As shown in FIG. 4 , the waste liquid bottle 1 comprises a first bottle body 11, and a first connection port 13 is provided on the top of the first bottle body 11; the first connection port 13 is connected to the interior of the waste liquid bottle 1. When in use, waste liquid can be discharged into the waste liquid bottle 1 through the first connection port 13.

[0040] In some examples of the present application, a first sensor 12 is also provided on the top of the first bottle body 11 to sense the liquid level inside the waste liquid bottle 1. When the liquid inside the waste liquid bottle 1 reaches a predetermined height, the operator is reminded to replace the waste liquid bottle 1 to prevent the waste liquid in the waste liquid bottle 1 from overflowing.

[0041] like Figure 3 , 4 As shown, the cleaning bottle 2 includes a second bottle body 21, and a second connection port 23 is provided on the top of the second bottle body 21; the second connection port 23 is connected to the inside of the cleaning bottle 2; and a connection pipe 24 is provided at one end of the second connection port 23 inserted into the cleaning bottle 2. When in use, the cleaning liquid can be sucked out of the cleaning bottle 2 through the second connection port 23.

[0042] In a specific example of the present application, one end of the connecting tube 24 away from the second connecting port 23 contacts the inner bottom surface of the cleaning bottle 2 , so as to completely suck out the cleaning liquid in the cleaning bottle 2 .

[0043] In some examples of the present application, a second sensor 22 is further provided on the top of the second bottle body 21 to sense the liquid level inside the cleaning bottle 2. When the liquid inside the cleaning bottle 2 reaches a predetermined height, the operator is reminded to replace the cleaning bottle 2 to prevent the cleaning bottle 2 from lacking cleaning liquid and thus failing to clean the centrifuge rotor.

[0044] In the description of this specification, the description with reference to the terms "embodiment", "some embodiments", "illustrative embodiment", "example", "specific example", "some examples", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0045] The embodiments described in this application are only part of the embodiments of the utility model, not all of the embodiments. Those skilled in the art can easily understand other advantages and effects of the utility model from the contents disclosed in this specification. The utility model can also be implemented or applied through other different specific implementation methods. In the absence of conflict, the following embodiments and features in the embodiments can be combined with each other. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

Claims

1. A cleaning bottle assembly, comprising a waste liquid bottle, a cleaning bottle, a sliding bracket and a mounting bracket; the waste liquid bottle and the cleaning bottle are both arranged inside the sliding bracket; characterized in that: The mounting bracket comprises a limiting portion, a slide and a limiting structure; the sliding bracket is slidably connected to the slide; the limiting portion is fixedly connected to the slide; one end of the limiting structure is fixedly connected to the limiting portion, and the other end is detachably connected to the sliding bracket.

2. A cleaning bottle assembly according to claim 1, characterized in that: The limiting structure is a magnetic attraction structure; the sliding bracket is made of one or more of iron, cobalt and nickel.

3. A cleaning bottle assembly according to claim 1, characterized in that: A partition is provided inside the sliding bracket; the partition divides the inside of the sliding bracket into two parts.

4. A cleaning bottle assembly according to claim 1, characterized in that: A sliding block is provided at the bottom of the sliding bracket; one end of the sliding block is fixedly connected to the sliding bracket, and the other end of the sliding block is slidably connected to the slideway.

5. A cleaning bottle assembly according to claim 1, characterized in that: A first connection port is provided on the top of the waste liquid bottle; the first connection port is communicated with the interior of the waste liquid bottle.

6. A cleaning bottle assembly according to claim 5, characterized in that: A first sensor is also provided on the top of the waste liquid bottle.

7. A cleaning bottle assembly according to claim 1, characterized in that: A second connection port is provided on the top of the cleaning bottle; the second connection port is communicated with the interior of the cleaning bottle; and a connection tube is provided at one end of the second connection port inserted into the cleaning bottle.

8. A cleaning bottle assembly according to claim 7, characterized in that: One end of the connecting pipe away from the second connecting port contacts the inner bottom surface of the cleaning bottle.

9. A cleaning bottle assembly according to claim 7, characterized in that: A second sensor is also provided on the top of the cleaning bottle.

10. A cleaning bottle assembly according to any one of claims 1 to 9, characterized in that: The limiting portion is arranged perpendicular to the slideway.

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