Amplification device for nucleic acid detection

By designing the magnetic ring and magnetic arc plate structure in the nucleic acid detection and amplification device, the problem of accidentally touching the heat cover adjustment knob is solved, the heating efficiency and amplification effect are improved, and the detection accuracy is ensured.

CN222182277UActive Publication Date: 2024-12-17QINGHAI DEAN MEDICAL TESTING LAB CO LTD
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Patent Information

Application Number
CN202420820396.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-19
Publication Date
2024-12-17
Estimated Expiration
2034-04-19

AI Technical Summary

Technical Problem

In the existing nucleic acid detection and amplification device, the exposed setting of the heat cover adjustment knob leads to false touch, affecting the heating efficiency and amplification effect, and reducing the detection accuracy.

Method used

A structure including a heat cover adjustment knob, magnetic ring, magnetic arc plate and return spring is designed. By pressing the button, the magnetic arc plate and magnetic ring are staggered, the knob limit is released, and the re-adsorption and fixation are re-activated to prevent accidental contact. .

Benefits of technology

It effectively prevents the heat cover adjustment knob from accidentally touching, improves heating efficiency and amplification effect, and ensures the stability and detection accuracy of the device.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses an amplification device for nucleic acid detection, which relates to the technical field of amplification devices and comprises an amplification instrument body, the top of the amplification instrument body is rotatably connected with a sealing cover, the top of the sealing cover is connected with a base, and the top of the base is provided with a hot cover adjusting knob. A peripheral ring is connected to the top of the base and surrounds the periphery of the hot cover adjusting knob, a magnetic ring is connected to the inner wall of the peripheral ring in a surrounding and attached mode, and when the hot cover adjusting knob is rotated, a worker needs to press a pressing button towards the inner side, so that a magnetic attraction arc plate moves downwards to be staggered from the magnetic ring, and limiting of the hot cover adjusting knob is relieved; after rotation is finished, the magnetic arc plate is loosened, the magnetic arc plate and the magnetic ring are attracted together again to fix the heat cover adjusting knob, and therefore even if mistaken touch occurs, the heat cover adjusting knob is not prone to rotating, stable work of the device and the heating efficiency of the device are further guaranteed, and the amplification effect of the device is improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of amplification devices, in particular to an amplification device for nucleic acid detection. Background Art

[0002] Nucleic acid testing is a method used to detect specific DNA fragments in samples, including PCR testing, LAMP testing, and CRISPR testing. Most existing nucleic acid tests often use PCR testing. PCR is the abbreviation of polymerase chain reaction, which is an enzymatic chemical reaction that can amplify the target gene to be tested in a test tube by 500,000 times or even millions of times in a very short period of time, greatly improving the sensitivity of genetic diagnosis and reducing the difficulty of analysis. When conducting PCR testing, staff need to place the PCR plate in the amplification instrument to amplify the gene.

[0003] When the thermal amplifier is in use, the staff needs to turn the heat cover adjustment knob to adjust the height of the heat cover to ensure sufficient heating of the sample. However, the existing heat cover adjustment knob is often exposed on the top of the sealing cover, which is easy to be accidentally touched during the experiment, causing the heat cover adjustment knob to rotate, thereby causing the heat cover height to change, affecting the heating efficiency of the device, reducing the amplification effect of the device, and even having a certain impact on the accuracy of subsequent detection processes. Utility Model Content

[0004] The purpose of the utility model is to provide an amplification device for nucleic acid detection to solve the technical problems mentioned in the above background technology.

[0005] The technical problem to be solved by the utility model can be achieved through the following technical solutions:

[0006] An amplification device for nucleic acid detection, comprising an amplifier body, a sealing cover rotatably connected to the top of the amplifier body, a base connected to the top of the sealing cover, a heat cover adjustment knob arranged on the top of the base, an outer peripheral ring connected to the top of the base surrounding the outer periphery of the heat cover adjustment knob, and a magnetic ring connected to the inner wall of the outer peripheral ring surrounding the inner periphery;

[0007] The heat cover adjustment knob is symmetrically provided with T-slots inside, a communicating movable slot is provided at the bottom of the T-slot, a wedge block is transversely provided inside the T-slot, a push button is connected to one side of the wedge block, an active rod is vertically provided inside the T-slot, a lifting rod transversely provided inside the movable slot is connected to the bottom end of the active rod, a spherical head is connected to the top of the active rod, a return spring is provided on the outside of the active rod, and one end of the lifting rod passing through the movable slot is connected to a magnetic arc plate.

[0008] As a further solution of the utility model: the push button passes through one end of the T-slot, the spherical head is located below the wedge block, and the head and tail ends of the reset spring are respectively connected to the bottom wall of the T-slot and the bottom of the spherical head.

[0009] As a further solution of the utility model: a display screen is arranged on the front of the amplifier body, and heat dissipation holes are arranged on both sides of the amplifier body.

[0010] As a further solution of the utility model: a data terminal is arranged on the back of the amplifier body, and a power terminal is arranged on the back of the amplifier body, and the power terminal is located on one side of the data terminal.

[0011] As a further solution of the utility model: a protective cover is rotatably connected to the top of the base, and the protective cover is located on one side of the outer ring.

[0012] Beneficial effects of the utility model:

[0013] When the utility model rotates the heat cover adjusting knob, the staff needs to press the push button inwardly, so that the magnetic arc plate moves downward and is offset from the magnetic ring, thereby releasing the limit on the heat cover adjusting knob. After the rotation is completed, the magnetic arc plate and the magnetic ring are loosened, and the magnetic arc plate and the magnetic ring are re-adsorbed together to fix the heat cover adjusting knob. Therefore, even if an accidental touch occurs, it is not easy to cause the heat cover adjusting knob to rotate, thereby further ensuring the stable operation of the device and the heating efficiency of the device, and improving the amplification effect of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] The utility model is further described below in conjunction with the accompanying drawings.

[0015] Figure 1 It is a three-dimensional schematic diagram of the whole device in the utility model;

[0016] Figure 2 It is a schematic rear view of the whole device in the utility model;

[0017] Figure 3 This utility model Figure 1 The enlarged schematic diagram at A in the middle;

[0018] Figure 4 It is a schematic diagram of the structure of the heat cover adjusting knob in the utility model.

[0019] In the figure: 1. Amplifier body; 2. Sealing cover; 3. Display screen; 4. Heat dissipation hole; 5. Data terminal; 6. Power terminal; 7. Base; 8. Heat cover adjustment knob; 9. Peripheral ring; 10. Magnetic ring; 11. T-slot; 12. Movable slot; 13. Wedge block; 14. Press button; 15. Active rod; 16. Lifting rod; 17. Spherical head; 18. Reset spring; 19. Magnetic arc plate; 20. Protective cover. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0021] like Figure 1-4 As shown, an amplification device for nucleic acid detection includes an amplifier body 1, a sealing cover 2 is rotatably connected to the top of the amplifier body 1, a sample pool is provided in the amplifier body 1 for placing and storing nucleic acid samples for amplification processing, the sample pool is sealed by the sealing cover 2 to prevent contamination, a heat cover is provided at the bottom of the sealing cover 2 for heating, a base 7 is connected to the top of the sealing cover 2, a heat cover adjustment knob 8 is provided on the top of the base 7, an outer peripheral ring 9 is connected to the periphery of the heat cover adjustment knob 8 on the top of the base 7, and a magnetic ring is connected to the inner wall of the outer peripheral ring 9 around the outer wall. Ring 10, T-slots 11 are symmetrically provided inside the heat cover adjustment knob 8, and a communicating movable slot 12 is provided at the bottom of the T-slot 11. A wedge block 13 is horizontally provided inside the T-slot 11, and a pressing button 14 is connected to one side of the wedge block 13. The pressing button 14 passes through one end of the T-slot 11, and the wedge block 13 can be driven to move inward by pressing the pressing button 14. An active rod 15 is vertically provided inside the T-slot 11, and a lifting rod 16 horizontally provided inside the movable slot 12 is connected to the bottom end of the active rod 15, and a spherical head 17 is connected to the top of the active rod 15. The spherical head 17 is located below the wedge block 13. A return spring 18 is provided on the outside of the active rod 15. The head and tail ends of the return spring 18 are respectively connected to the bottom wall of the T-slot 11 and the bottom of the spherical head 17. One end of the lifting rod 16 that passes through the movable slot 12 is connected to a magnetic arc plate 19. The magnetic attraction of the magnetic arc plate 19 and the magnetic ring 10 can fix the heat cover adjustment knob 8. When the heat cover adjustment knob 8 needs to be rotated, the staff needs to press the push button 14 inward to drive the wedge block 13 to move to one side. The bottom of the wedge block 13 is an inclined surface. During the movement, the spherical head 17 will be squeezed downward, so that the reset spring 18 will be deformed and compressed, and the active rod 15 will drive the lifting rod 16 to descend. At this time, the magnetic arc plate 19 will move downward and staggered with the magnetic ring 10, and the two will no longer be adsorbed together, releasing the fixation of the heat cover adjustment knob 8. At this time, the heat cover adjustment knob 8 can be smoothly turned. After the adjustment is completed, the staff lets go, and under the action of the elastic force of the reset spring 18, the active rod 15 and the lifting rod 16 are reset upward, and the magnetic arc plate 19 forms a magnetic fixation with the outer ring 9 to the heat cover adjustment knob 8.

[0022] A display screen 3 is provided on the front of the amplifier body 1, heat dissipation holes 4 are opened on both sides of the amplifier body 1, a data terminal 5 is provided on the back of the amplifier body 1, and a power terminal 6 is provided on the back of the amplifier body 1. The power terminal 6 is located on one side of the data terminal 5.

[0023] The top of the base 7 is rotatably connected with a protective cover 20, which is located on one side of the outer ring 9. The protective cover 20 can cover and protect the heat cover adjustment knob 8, further reducing the probability of accidental touch.

[0024] The working principle of the utility model is as follows: when the device is working, the sample can be placed in the sample pool in the amplification instrument body 1, the sealing cover 2 is closed for sealing, and the push button 14 is pressed inwardly so that the magnetic arc plate 19 is offset from the magnetic ring 10, and the fixation of the heat cover adjustment knob 8 is released, so that the heat cover adjustment knob 8 is turned to adjust the height of the heat cover. After the adjustment is completed, the staff lets go, and under the action of the elastic force of the reset spring 18, the various components are reset, and the magnetic arc plate 19 forms a magnetic bond with the outer ring 9 to fix the heat cover adjustment knob 8.

[0025] The above is a detailed description of an embodiment of the utility model, but the content is only a preferred embodiment of the utility model and cannot be considered to limit the scope of implementation of the utility model. All equivalent changes and improvements made within the scope of application of the utility model should still fall within the scope of the patent coverage of the utility model.

Claims

1. An amplification device for nucleic acid detection, comprising an amplifier body (1), the top of which is rotatably connected to a sealing cover (2); characterized in that: The top of the sealing cover (2) is connected to a base (7), a heat cover adjustment knob (8) is arranged on the top of the base (7), an outer peripheral ring (9) is connected to the top of the base (7) surrounding the periphery of the heat cover adjustment knob (8), and a magnetic ring (10) is connected to the inner wall of the outer peripheral ring (9) in a surrounding and fitting manner; The heat cover adjusting knob (8) is symmetrically provided with T-shaped slots (11) inside, and a communicating movable slot (12) is provided at the bottom of the T-shaped slot (11). A wedge block (13) is transversely provided inside the T-shaped slot (11), and a pressing button (14) is connected to one side of the wedge block (13). An active rod (15) is vertically provided inside the T-shaped slot (11), and a lifting rod (16) transversely provided inside the movable slot (12) is connected to the bottom end of the active rod (15). A spherical head (17) is connected to the top of the active rod (15), and a return spring (18) is provided on the outside of the active rod (15). One end of the lifting rod (16) passing through the movable slot (12) is connected to a magnetic arc absorption plate (19).

2. A nucleic acid detection amplification device according to claim 1, characterized in that: The push button (14) passes through one end of the T-slot (11), the spherical head (17) is located below the wedge block (13), and the head and tail ends of the return spring (18) are respectively connected to the bottom wall of the T-slot (11) and the bottom of the spherical head (17).

3. A nucleic acid detection amplification device according to claim 1, characterized in that: A display screen (3) is provided on the front of the amplifier body (1), and heat dissipation holes (4) are provided on both sides of the amplifier body (1).

4. A nucleic acid detection amplification device according to claim 1, characterized in that: A data terminal (5) is arranged on the back of the amplifier body (1), and a power terminal (6) is arranged on the back of the amplifier body (1), wherein the power terminal (6) is located on one side of the data terminal (5).

5. The amplification device for nucleic acid detection according to claim 1, characterized in that: The top of the base (7) is rotatably connected to a protective cover (20), and the protective cover (20) is located on one side of the outer ring (9).