Target table device of time-of-flight mass spectrometer and time-of-flight mass spectrometer

By simplifying horizontal adjustment in the target platform device of the time-of-flight mass spectrometer using adjustment bolts and fixing springs, and achieving accurate alignment and stability of the target plate through the slide rail structure, the complex leveling of the target platform device in the prior art is solved. The problem of poor stability improves the accuracy and sensitivity of detection.

CN222281921UActive Publication Date: 2024-12-31RONGZHI BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202421019366.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-11
Publication Date
2024-12-31
Estimated Expiration
2034-05-11

AI Technical Summary

Technical Problem

The leveling mechanism of the existing target table device of the time-of-flight mass spectrometer is complex in operation and has poor stability, which affects the authenticity and repetition of the detection.

Method used

A target table device including a base, an adjustment plate, a target table, a first adjustment bolt and a fixing spring is designed. The level of the adjustment plate is adjusted by adjusting the bolt and the stability of the adjustment plate is improved by fixing spring, thereby simplifying the The horizontal adjustment process is used to realize the movement and angle adjustment of the target platform through the slide rail and slide structure to ensure the accurate alignment and stability of the target plate.

Benefits of technology

The rapid leveling and stability of the target plate are achieved, the sensitivity and accuracy of detection are improved, the leveling process is simplified, and the controllability of the ion flight trajectory is ensured.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of mass spectrometer equipment, particularly provides a target table device of a time-of-flight mass spectrometer and the time-of-flight mass spectrometer, and aims to solve the problems that a leveling mechanism of a target table device of a conventional time-of-flight mass spectrometer is complex in operation and poor in stability after leveling. In order to achieve the purpose, the target table device comprises a base, the adjusting plate is mounted on the base; the target carrying table is mounted on the adjusting plate; the two ends of each first adjusting bolt are in threaded connection with the base and the adjusting plate correspondingly so as to adjust the distance between the base and the adjusting plate, and therefore the levelness of the adjusting plate can be adjusted; the two ends of the fixing spring are fixedly connected with the base and the adjusting plate correspondingly so that the adjusting plate can be tensioned in the direction of the base. Through the arrangement, the levelness of the target carrying table can be quickly adjusted through the combination of the adjusting bolts and the fixing springs, and the stability of the leveled target carrying table can be guaranteed.
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Description

Technical Field

[0001] The utility model relates to the technical field of mass spectrometer equipment, and specifically provides a target platform device of a time-of-flight mass spectrometer and a time-of-flight mass spectrometer. Background Art

[0002] The two-dimensional moving target stage is a target stage used to carry the target plate in the time-of-flight mass spectrometer. The target plate is moved by moving the target stage in the horizontal XY direction, thereby controlling the different target points on the target plate to align with the laser beam emitted by the ion source. The target plate and the laser beam must remain relatively perpendicular so that the ions generated after the sample to be tested on the target point is excited can enter the time-of-flight analyzer.

[0003] Therefore, after installation, the two-dimensional mobile target stage needs to be adjusted to a horizontal level so that it remains perpendicular to the vertical laser beam. Otherwise, the flight trajectory of the ions after the sample is excited will be uncontrollable, which will seriously affect the authenticity and repeatability of the time-of-flight mass spectrometer detection. This makes the leveling of the two-dimensional mobile target stage very important.

[0004] However, the existing leveling mechanism of the target stage device of the time-of-flight mass spectrometer is complicated to operate and has the problem of poor stability after leveling.

[0005] Therefore, this field needs a new technical solution to solve the above problems. Utility Model Content

[0006] The utility model aims to solve the above technical problem, that is, to solve the problem that the leveling mechanism of the target platform device of the existing time-of-flight mass spectrometer is complicated in operation and has poor stability after leveling.

[0007] In the first aspect, the utility model provides a target stage device for a time-of-flight mass spectrometer, the target stage device comprising: a base; an adjustment plate, the adjustment plate being mounted on the base; a target carrier, the target carrier being mounted on the adjustment plate; a plurality of first adjustment bolts, the two ends of the first adjustment bolts being threadedly connected to the base and the adjustment plate, respectively, to adjust the distance between the adjustment plate and the base, so as to be able to adjust the horizontality of the adjustment plate; a fixing spring, the two ends of the fixing spring being fixedly connected to the base and the adjustment plate, respectively, to tighten the adjustment plate toward the base.

[0008] In a preferred technical solution of the above-mentioned target platform device, the target platform device further comprises a moving component, the moving component is slidably connected to the adjustment plate, and the target platform is mounted on the moving component.

[0009] In the preferred technical solution of the above-mentioned target platform device, the moving component includes a first slide rail arranged on the adjustment plate along a first direction, a second slide rail extending along a second direction perpendicular to the first direction and slidably connected to the first slide rail, and a slider slidably connected to the second slide rail, and the target platform is mounted on the slider.

[0010] In the preferred technical solution of the above-mentioned target platform device, the target platform device also includes a connecting block and a plurality of second adjusting bolts, both ends of the second adjusting bolts are respectively threadedly connected to the connecting block and the slider to adjust the distance between the connecting block and the slider, and the target platform is fixedly connected to the connecting block.

[0011] In a preferred technical solution of the above-mentioned target stage device, the target stage is provided with a first limiting structure, and the first limiting structure can limit the target plate assembly included in the time-of-flight mass spectrometer.

[0012] In a second aspect, the utility model provides a time-of-flight mass spectrometer, which includes a shell, a target plate assembly and the above-mentioned target stage device, wherein the target stage device and the target plate assembly are located in the shell, and the target carrier stage loads the target plate assembly.

[0013] In a preferred technical solution of the above-mentioned target stage device, the target plate assembly includes a target plate and a target holder, and the target plate is detachably connected to the target holder.

[0014] In a preferred technical solution of the above-mentioned target stage device, the target plate assembly further includes a magnet mounted on the target holder, and the magnet can adsorb the target plate on the target holder.

[0015] In the preferred technical solution of the above-mentioned target stage device, a second limiting structure is further provided on the target support, and the second limiting structure can limit the target plate.

[0016] In the preferred technical solution of the above-mentioned target stage device, the time-of-flight mass spectrometer also includes a target changing device located outside the shell, and a target changing port is provided on the shell. The target changing device is connected to the vacuum chamber through the target changing port to replace the target plate.

[0017] In the case of adopting the above technical solution, the target platform device of the utility model includes: a base; an adjustment plate, the adjustment plate is mounted on the base; a target platform, the target platform is mounted on the adjustment plate; a plurality of first adjustment bolts, the two ends of the first adjustment bolts are respectively threadedly connected to the base and the adjustment plate to adjust the distance between the adjustment plate and the base, so that the horizontality of the adjustment plate can be adjusted; a fixed spring, the two ends of the fixed spring are respectively fixedly connected to the base and the adjustment plate to tighten the adjustment plate toward the base. Through such a setting, on the one hand, the horizontal adjustment mechanism of the target platform device is simplified, which is helpful for the rapid adjustment of the horizontality, thereby realizing the rapid leveling of the target platform and the target plate; on the other hand, the tensioning effect of the fixed spring on the adjustment plate improves the stability of the adjustment plate, the target platform and the target plate after leveling, ensuring the sensitivity and accuracy of the detection.

[0018] Furthermore, the target stage device of the utility model also includes a moving component, which is slidably connected to the adjustment plate, and the target stage is installed on the moving component. Through such an arrangement, the moving component can drive the target stage and the target plate assembly to move, so as to adjust the position of different target points on the target plate, so that the target point can be aligned with the laser beam emitted by the ion source, so that the sample on the target point can be accurately excited to generate ions, and the target plate assembly can also be transported to the outside.

[0019] Furthermore, the mobile assembly of the utility model comprises a first slide rail arranged on the adjustment plate along a first direction, a second slide rail extending along a second direction perpendicular to the first direction and slidably connected to the first slide rail, and a slider slidably connected to the second slide rail, and the target platform is mounted on the slider. Through such an arrangement, the smoothness and stability of the operation of the mobile assembly are ensured by utilizing the characteristics of simple slide structure and mature technology.

[0020] Furthermore, the target platform device of the utility model also includes a connecting block and a plurality of second adjusting bolts, the two ends of the second adjusting bolts are respectively threadedly connected to the connecting block and the slider to adjust the distance between the connecting block and the slider, and the target platform is fixedly connected to the connecting block. Through such an arrangement, the angle of the target platform and the target plate assembly can be fine-tuned by the adjusting block and the second adjusting bolts, so that the angle of the target plate assembly can adapt to the position of the target changing port and the target changing device, so as to be able to dock accurately, which is conducive to the loading and removal of the target plate.

[0021] Furthermore, the target carrier of the utility model has a first limiting structure, which can limit the target plate assembly included in the time-of-flight mass spectrometer. Through such a setting, on the one hand, the target plate assembly is fixed to prevent the target plate assembly from being offset or falling off during the movement of the target carrier; on the other hand, it is convenient to take and place the target carrier assembly.

[0022] In addition, the time-of-flight mass spectrometer further provided by the utility model on the basis of the above-mentioned target stage device includes a shell, a target plate assembly and the above-mentioned target stage device, wherein the target stage device and the target plate assembly are located in the shell, and the target stage is loaded with the target plate assembly. Due to the use of the above-mentioned target stage device, the technical effect possessed by the above-mentioned time-of-flight mass spectrometer is achieved. Compared with the time-of-flight mass spectrometer before the improvement, the leveling process of the target plate of the time-of-flight mass spectrometer of the utility model is simple and reliable, so that the flight trajectory of the ions generated after the sample is excited is concentrated, and can smoothly enter the time-of-flight analyzer, thereby improving the sensitivity and accuracy of the detection.

[0023] Furthermore, the target plate assembly of the utility model includes a target plate and a target holder, and the target plate and the target holder are detachably connected. Through such a setting, on the one hand, it is convenient to disassemble and replace the target plate, realize the reuse of the target plate, and reduce the cost; on the other hand, the target holder can play a role in fixing and protecting the target plate.

[0024] Furthermore, the target plate assembly of the utility model further comprises a magnet mounted on the target holder, and the magnet can adsorb the target plate on the target holder. Through such an arrangement, the stability of the target plate on the target holder is enhanced, and the target plate is prevented from deflecting or falling off.

[0025] Furthermore, the target holder of the utility model is also provided with a second limiting structure, which can limit the target plate. Through such a setting, namely, through the joint action of the second limiting structure and the magnet, the stability of the target plate on the target holder is further enhanced.

[0026] Furthermore, the time-of-flight mass spectrometer of the utility model further includes a target changing device located outside the housing, and a target changing port is provided on the housing, and the target changing device is connected to the vacuum chamber through the target changing port to replace the target plate. With such a configuration, the target plate can be replaced by using the target changing device, so as to maximize the vacuum degree inside the housing during the target changing process. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The preferred embodiments of the present invention are described below in conjunction with the accompanying drawings, in which:

[0028] Figure 1 This is a schematic diagram of the structure of the target platform device of the utility model. Figure 1 ;

[0029] Figure 2 This is a schematic diagram of the structure of the target platform device of the utility model. Figure 2 ;

[0030] Figure 3 This is a schematic diagram of the structure of the target platform device of the utility model. Figure 3 ;

[0031] Figure 4 yes Figure 3 Sectional view at AA in the middle;

[0032] Figure 5 It is an exploded view of the target plate assembly of the utility model.

[0033] List of reference numerals:

[0034] 1. Target stage device; 11. Base; 12. Adjustment plate; 13. Target stage; 131. First limiting structure; 14. First adjusting bolt; 15. Fixing spring; 161. First slide rail; 162. Second slide rail; 163. Slider; 17. Connecting block; 18. Second adjusting bolt; 2. Target plate assembly; 21. Target plate; 22. Target holder; 221. Second limiting structure; 222. Mounting groove; 23. Magnet; 3. Shell; 31. Target changing port; 4. Target changing device; 41. Sealing cover. DETAILED DESCRIPTION

[0035] The preferred embodiments of the present invention are described below with reference to the accompanying drawings. It should be understood by those skilled in the art that these embodiments are only used to explain the technical principles of the present invention and are not intended to limit the protection scope of the present invention.

[0036] It should be noted that in the description of the present invention, the terms "inside", "outside", "upper", "lower", "top", "bottom" and other terms indicating directions or positional relationships are based on the directions or positional relationships shown in the drawings, which are only for the convenience of description, and do not indicate or imply that the device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation of the present invention. In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.

[0037] In addition, it should be noted that in the description of the present invention, unless otherwise clearly specified and limited, the terms "set", "connect", and "install" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection. For those skilled in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0038] Based on the problems pointed out in the background technology that the leveling mechanism of the target platform device of the existing time-of-flight mass spectrometer is complicated to operate and has poor stability after leveling. The utility model provides a target platform device of a time-of-flight mass spectrometer and a time-of-flight mass spectrometer, by arranging an adjusting bolt and a fixing spring between the base of the target platform device and the adjustment plate, using the adjusting bolt to adjust the horizontality of the adjustment plate, and using the fixing spring to improve the stability of the adjustment plate, thereby realizing rapid leveling of the target plate and stable maintenance after leveling.

[0039] A time-of-flight mass spectrometer is an instrument that uses electronic measurement technology to measure the mass-to-charge ratio (m / z) of ions and their intensity. It uses an injection system to introduce the sample to be tested into the mass spectrometer, uses an ion source to ionize it, and uses an electric field to separate the ions according to their mass-to-charge ratio in the mass analyzer. The detector records the separated ion signals according to their mass-to-charge ratio and intensity.

[0040] Matrix-assisted laser desorption (MALDI) is also one of the soft ionization techniques for mass spectrometry to ionize samples. Matrix-assisted laser desorption is to mix the analyte and the matrix in a certain proportion and then irradiate with laser. After absorbing the laser energy, the matrix transfers the laser energy to the analyte molecules, causing them to vaporize and ionize to form ions, including analyte ions and matrix ions. The mass spectrometer using matrix-assisted laser desorption technology is usually a matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometer.

[0041] Specifically, Figures 1 to 5 As shown, the time-of-flight mass spectrometer of the utility model includes a target plate assembly 2, and the target platform device 1 includes: a base 11; an adjustment plate 12, the adjustment plate 12 is installed on the base 11; a target platform 13, the target platform 13 is installed on the adjustment plate 12; a plurality of first adjustment bolts 14, the two ends of the first adjustment bolts 14 are respectively threadedly connected to the base 11 and the adjustment plate 12 to adjust the distance between the adjustment plate 12 and the base 11, so that the horizontality of the adjustment plate 12 can be adjusted; a fixing spring 15, the two ends of the fixing spring 15 are respectively fixedly connected to the base 11 and the adjustment plate 12 to tighten the adjustment plate 12 toward the base 11.

[0042] Exemplarily, the time-of-flight mass spectrometer of the present invention includes a vacuum chamber surrounded by a shell 3, inside which are arranged a target stage device 1 and a target plate assembly 2, a deflection electrode assembly (not shown in the figure), a flight tube (not shown in the figure), a detector (not shown in the figure) and a light source assembly (not shown in the figure) from bottom to top. The light source assembly can irradiate the emitted laser onto the matrix on the target plate 21 and the crystals of the sample to be tested, thereby generating ions, which are finally incident into the detector through the flight tube.

[0043] The vacuum chamber is the main space for ion flight in the matrix-assisted laser desorption time-of-flight mass spectrometer, which can ensure that the ionized ions will not be affected by the collision of air molecules during the flight.

[0044] The target stage device 1 of the utility model is installed at the bottom of the vacuum chamber, and is used to carry the target plate assembly 2, and can drive the target plate assembly 2 to move in the horizontal direction to control different target points on the target plate 21 to align with the laser beam emitted by the ion source. At the same time, since the target plate 21 and the laser beam must remain relatively vertical so that the ions generated after the sample to be tested on the target point is excited can enter the flight tube, the target stage device 1 needs to adjust the target plate 21 to a horizontal position after installation so that it remains perpendicular to the vertical laser beam, otherwise the flight trajectory of the ions after the sample is excited will be uncontrollable, thereby seriously affecting the authenticity and repeatability of the time-of-flight mass spectrometer detection.

[0045] Based on this, the base 11 of the utility model is horizontally arranged at the bottom of the vacuum chamber, and the adjustment plate 12 is installed on the top surface of the base 11 through the first adjustment bolt 14 and the fixing spring 15. The base 11 and the adjustment plate 12 are both arranged as rectangular plate structures. The bottom surface of the adjustment plate 12 is not in direct contact with the top surface of the base 11, but a certain gap is maintained to leave space for adjustment of the distance between the two. The target platform 13 is installed in the middle of the adjustment plate 12, and its horizontality can change with the adjustment plate 12.

[0046] In practical applications, technicians in this field can flexibly set the installation position and quantity of the first adjusting bolt 14 and the fixing spring 15, as long as the horizontal adjustment of the adjusting plate 12 can be achieved. In the present solution, it is preferred to set three groups of first adjusting bolts 14 and fixing springs 15, each group includes a first adjusting bolt 14 and a fixing spring 15, two of which are arranged on one side edge of the adjusting plate 12 and the base 11, and the other group is arranged on the other side edge of the adjusting plate 12 and the base 11. The two ends of the first adjusting bolt 14 are respectively threadedly connected to the threaded holes on the base 11 and the adjusting plate 12, thereby forming three adjustment points, and the connecting line of the three adjustment points forms a triangle, which is conducive to the adjustment of the horizontality and can maintain the stability of the adjusting plate 12 after leveling.

[0047] By rotating the three first adjusting bolts 14, the distance between the adjusting plate 12 and the base 11 at each first adjusting bolt 14 can be changed respectively, and then the horizontality of the adjusting plate 12 can be changed, so as to realize the leveling of the target platform 13 and the target plate assembly 2 on the adjusting plate 12. The fixing spring 15 is always in a tensioned state between the adjusting plate 12 and the base 11, which can prevent the frame movement caused by the thread matching clearance between the first adjusting bolt 14 and the base 11 and the adjusting plate 12, and effectively improves the stability of the adjusting plate 12, the target platform 13 and the target plate assembly 2 after leveling.

[0048] Therefore, such a setting not only simplifies the horizontal adjustment mechanism of the target stage device 1, helps to quickly adjust the horizontality, and realizes rapid leveling of the target stage 13 and the target plate 21; it can also improve the stability of the adjustment plate 12, the target stage 13 and the target plate 21 after leveling by tightening the adjustment plate 12 and the base 11 through the fixed spring 15, thereby ensuring the stability of the ion emission trajectory and ensuring the sensitivity and accuracy of the detection.

[0049] Preferably, if Figure 1 and Figure 2 As shown, the target platform device 1 of the present invention further comprises a moving component, the moving component is slidably connected to the adjustment plate 12, and the target platform 13 is mounted on the moving component.

[0050] The moving component is slidably connected to the top surface of the adjustment plate 12, and can slide freely on the adjustment plate 12, and drive the target carrier 13 and the target plate assembly 2 to move synchronously, so as to adjust the position of different target points on the target plate 21, so that the target point can be aligned with the laser beam emitted by the ion source, and then the sample on the target point can be accurately excited to generate ions.

[0051] In addition, the moving assembly can also transport the target plate assembly 2 , and can transport the target plate assembly 2 to the outside of the housing 3 to replace the target plate 21 .

[0052] Preferably, if Figure 1 and Figure 2 As shown, the moving component of the utility model includes a first slide rail 161 arranged on the adjustment plate 12 along a first direction (i.e., the X-axis direction in the figure), a second slide rail 162 extending along a second direction (i.e., the Y-axis direction in the figure) and slidably connected to the first slide rail 161, and a slider 163 slidably connected to the second slide rail 162, and the target platform 13 is mounted on the slider 163.

[0053] In addition, the moving component also includes a driving device, which can be configured as a driving motor or a cylinder, etc., which can drive the second slide rail 162 to slide on the first slide rail 161 along the X-axis, and the slider 163 to slide on the second slide rail 162 along the Y-axis direction, thereby realizing the movement of the target platform 13 and the target plate assembly 2.

[0054] It should be noted that, in practical applications, those skilled in the art can also flexibly set the moving component to other structural forms, such as pulleys and slideways, etc., which are all conventional technical means in the field, as long as they can drive the target carrier 13 and the target plate assembly 2 to move. Such flexible adjustment and change does not deviate from the principle and scope of the utility model, and should be limited within the protection scope of the utility model.

[0055] The preferred slide rail structure of the utility model is simple and reliable, with mature technology, which ensures the smoothness and stability of the moving component during operation.

[0056] Preferably, if Figure 1 and Figure 2 As shown, the target platform device 1 of the utility model also includes a connecting block 17 and a plurality of second adjusting bolts 18, and the two ends of the second adjusting bolts 18 are respectively threadedly connected to the connecting block 17 and the slider 163 to adjust the distance between the connecting block 17 and the slider 163, and the target platform 13 is fixedly connected to the connecting block 17.

[0057] It should be noted that a target changing port 31 is provided on the shell 3, and the target changing port 31 is docked with the end of the first slide rail 161. Controlling the slider 163 to move along the first slide rail 161 can transport the target carrier 13 to the target changing port 31, and send the target carrier 13 and the target plate assembly 2 out of the shell 3 through the target changing port 31 to replace the target plate 21.

[0058] In order to maximize the vacuum degree inside the shell 3, the target changing port 31 is adapted to the size of the target loading platform 13, and the size of the target changing port 31 can just allow the target loading platform 13 to pass through. Therefore, before controlling the target loading platform 13 to enter the target changing port 31, it is necessary to adjust the angle and position of the target loading platform 13 so that it can smoothly enter the target changing port 31.

[0059] Therefore, similar to the adjustment plate 12 and the first adjustment bolt 14, the angles of the target platform 13 and the target plate assembly 2 can be fine-tuned through the adjustment block and the second adjustment bolt 18, so that the target platform 13 can adapt to the position of the target changing port 31 and the target changing device 4, so that it can be accurately docked with the target changing port 31, thereby facilitating the loading and removal of the target plate 21.

[0060] The target loading platform 13 is fixed to one side of the connecting block 17 close to the target changing port 31 , and the bottom is suspended in the air, so that the target loading platform 13 can pass through the target changing port 31 as a whole.

[0061] Preferably, if Figure 1 As shown, the target carrier 13 of the present invention has a first limiting structure 131 , and the first limiting structure 131 can limit the target plate assembly 2 included in the time-of-flight mass spectrometer.

[0062] Exemplarily, the first limiting structure 131 is configured as a limiting groove, the size of which is adapted to the target plate assembly 2, and can fix the target plate assembly 2 on the target platform 13 to prevent the target plate assembly 2 from shifting or falling off as the target platform 13 moves; at the same time, an opening is provided at one end of the limiting groove close to the target changing port 31 to facilitate the sliding in and out of the target plate assembly 2, making the target changing operation more convenient.

[0063] In addition, the time-of-flight mass spectrometer further provided by the present invention on the basis of the above-mentioned target stage device 1 includes a shell 3, a target plate assembly 2 and the above-mentioned target stage device 1, wherein the target stage device 1 and the target plate assembly 2 are located in the shell, and the target carrier 13 is loaded with the target plate assembly 2. Due to the use of the above-mentioned target stage device 1, the technical effect possessed by the above-mentioned target stage device 1 is possessed. Compared with the time-of-flight mass spectrometer before the improvement, the time-of-flight mass spectrometer of the present invention has a simpler and more reliable leveling process for the target plate 21, so that the flight trajectory of the ions generated after the sample is excited is more concentrated, and can smoothly enter the time-of-flight analyzer, thereby improving the sensitivity and accuracy of the detection.

[0064] Preferably, if Figure 5 As shown, the target plate assembly 2 of the present invention comprises a target plate 21 and a target holder 22 , and the target plate 21 and the target holder 22 are detachably connected.

[0065] Exemplarily, the target plate 21 is configured as a sheet structure, which is easy to deform. The setting of the target holder 22 can provide certain protection and support for the target plate 21. At the same time, the detachable structure facilitates the disassembly, assembly and replacement of the target plate 21, thereby achieving the reuse of the target plate 21 and reducing costs. In addition, compared with the target carrier 13 installed inside the shell 3, the flatness of the surface of the target holder 22 is also easier to observe.

[0066] Preferably, if Figure 5 As shown, the target plate assembly 2 of the present invention further includes a magnet 23 mounted on the target holder 22 , and the magnet 23 can adsorb the target plate 21 onto the target holder 22 .

[0067] Exemplarily, a plurality of mounting grooves 222 for mounting magnets 23 are provided on the target holder 22, and the magnets 23 can be embedded in the target holder 22, so that the magnets 23 will not protrude from the surface of the target holder 22 and affect the horizontality of the target plate 21. The target plate 21 is set to be made of metal material. The target plate 21 in this scheme preferably uses 416 stainless steel. When the target plate 21 is placed on the surface of the target holder 22, the magnets 23 will generate suction on the target plate 21, thereby limiting the movement of the target plate 21 on the surface of the target holder 22, enhancing the stability of the target plate 21 on the target holder 22, and effectively avoiding the displacement or falling off of the target plate 21.

[0068] Preferably, if Figure 5 As shown, the target holder 22 of the present invention is further provided with a second limiting structure 221 , and the second limiting structure 221 can limit the target plate 21 .

[0069] Exemplarily, the second limiting structure 221 is configured as a slot, similar to the slot structure on the target carrier 13, the three sides of the slot have a blocking structure, and the other side is an opening, so that the second limiting structure 221 can both limit the target plate 21 and facilitate the removal and placement of the target plate 21.

[0070] The second limiting structure 221 and the magnet 23 work together to further enhance the stability of the target plate 21 on the target holder 22 .

[0071] Preferably, if Figures 1 to 4 As shown, the time-of-flight mass spectrometer of the present invention further includes a target changing device 4 located outside the housing 3 . A target changing port 31 is provided on the housing 3 . The target changing device 4 is connected to the vacuum chamber through the target changing port 31 to replace the target plate 21 .

[0072] Exemplarily, the target changing device 4 is configured as a pipeline structure, with a target changing channel formed inside. The end close to the shell 3 is sealed and connected to the target changing port 31, so that the target carrier 13 and the target plate 21 enter the target changing channel through the target changing port 31, and a sealing cover 41 is provided at the end away from the shell 3, which can close the target changing channel to maintain the vacuum degree inside it.

[0073] When it is necessary to change the target, the slider 163 slides along the first slide rail 161 toward the target changing device 4, and sends the target platform 13 and the target plate assembly 2 into the target changing channel through the target changing port 31. When the target platform 13 completely enters the target changing channel, the connection between the target platform 13 and the slider 163 can completely block the target changing port 31 to maintain the vacuum degree in the shell 3. At this time, at the other end of the target changing channel, the sealing cover 41 can be opened to replace the target plate 21. After the replacement is completed, the sealing cover 41 must be closed first, and then the target changing channel must be evacuated. When the vacuum degree in the target changing channel approaches or reaches the vacuum degree in the shell 3, the target platform 13 and the target plate assembly 2 are retracted into the shell 3 together, thereby maximizing the vacuum degree inside the shell 3 during the target changing process.

[0074] So far, the technical solution of the present invention has been described in conjunction with the preferred embodiments shown in the accompanying drawings. However, it is easy for those skilled in the art to understand that the protection scope of the present invention is obviously not limited to these specific embodiments. Without departing from the principle of the present invention, those skilled in the art can make equivalent changes or substitutions to the relevant technical features, and the technical solutions after these changes or substitutions will fall within the protection scope of the present invention.

Claims

1. A target station device for a time-of-flight mass spectrometer, characterized in that: The target platform device comprises: Pedestal; An adjustment plate, the adjustment plate being mounted on the base; A target loading platform, wherein the target loading platform is mounted on the adjustment plate; a plurality of first adjusting bolts, wherein two ends of the first adjusting bolts are respectively threadedly connected to the base and the adjusting plate to adjust the distance between the adjusting plate and the base, thereby being able to adjust the horizontality of the adjusting plate; A fixing spring, two ends of which are fixedly connected to the base and the adjusting plate respectively, so as to tighten the adjusting plate toward the base.

2. The target platform device according to claim 1, characterized in that: The target platform device also includes a moving component, which is slidably connected to the adjustment plate, and the target platform is installed on the moving component.

3. The target platform device according to claim 2, characterized in that: The moving assembly includes a first slide rail arranged on the adjustment plate along a first direction, a second slide rail extending along a second direction perpendicular to the first direction and slidably connected to the first slide rail, and a slider slidably connected to the second slide rail, and the target platform is mounted on the slider.

4. The target platform device according to claim 3, characterized in that: The target platform device also includes a connecting block and a plurality of second adjusting bolts, the two ends of the second adjusting bolts are respectively threadedly connected to the connecting block and the slider to adjust the distance between the connecting block and the slider, and the target platform is fixedly connected to the connecting block.

5. The target stage device according to any one of claims 1 to 4, characterized in that: The target platform has a first limiting structure, and the first limiting structure can limit the target plate assembly included in the time-of-flight mass spectrometer.

6. A time-of-flight mass spectrometer, characterized in that: The time-of-flight mass spectrometer comprises a housing, a target plate assembly and a target stage device according to any one of claims 1 to 5, wherein the target stage device and the target plate assembly are located in the housing, and the target carrying stage carries the target plate assembly.

7. The time-of-flight mass spectrometer according to claim 6, characterized in that The target plate assembly comprises a target plate and a target holder, and the target plate is detachably connected to the target holder.

8. The time-of-flight mass spectrometer according to claim 7, characterized in that: The target plate assembly further comprises a magnet mounted on the target holder, and the magnet can adsorb the target plate onto the target holder.

9. The time-of-flight mass spectrometer according to claim 7 or 8, characterized in that: The target holder is also provided with a second limiting structure, and the second limiting structure can limit the target plate.

10. The time-of-flight mass spectrometer according to claim 6, characterized in that: The time-of-flight mass spectrometer further comprises a target changing device located outside the shell. The shell is provided with a target changing port. The target changing device is connected to the shell through the target changing port to replace the target plate.