Freezer for cryopreservation of stem cells

Abstract

The utility model discloses a freezing box for cryopreservation of stem cells, which comprises a box body, a placing groove is arranged inside the box body, a plurality of groups of inner containers are arranged inside the placing groove, the inner containers are arranged in a columnar structure, a liquid nitrogen freezing bin is arranged inside the box body, an inlet is arranged on the upper portion of the liquid nitrogen freezing bin, and the liquid nitrogen freezing bin is arranged in the box body. And a sealing cover is arranged at the inlet. The containing groove is formed in the box body, the multiple sets of inner containers are arranged in the containing groove, the inner containers are of a columnar structure, stem cell test tubes can be conveniently placed, the liquid nitrogen freezing bin is arranged in the box body, the inlet is formed in the upper portion of the liquid nitrogen freezing bin, and the sealing cover is arranged at the inlet. By means of the arrangement, liquid nitrogen can be conveniently added, the liquid nitrogen can be added in time in the transferring process, and therefore the cryopreservation time is guaranteed, the box cover is arranged on the top of the box body, the sealing block is arranged on the lower portion of the box cover, the sealing block and the containing groove are mutually embedded, and the sealing performance of the box body is guaranteed.

Description

Technical Field

[0001] The utility model relates to the technical field of stem cell cryopreservation, and more specifically to a freezing box for cryopreservation of stem cells. Background Art

[0002] Stem cell cryopreservation is a major method of cell preservation, and its main purpose is to achieve long-term preservation by placing stem cells in a low-temperature environment to reduce cell metabolism. This technology can temporarily remove stem cells from the growth state while maintaining their cell characteristics so that they can be revived and used when needed.

[0003] The cryopreservation of stem cells also needs to maintain the storage temperature during transportation, and the general incubator cannot guarantee long-distance transportation. Therefore, a new technical solution is needed to solve the problem. Utility Model Content

[0004] The utility model aims to provide a freezing box for cryopreservation of stem cells, which solves the problem that the freezing and preservation of stem cells also needs to ensure the preservation temperature during transportation, and the general insulation box cannot ensure long-distance transportation.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a freezing box for cryopreservation of stem cells, comprising: a box body, a placement groove is arranged inside the box body, and a plurality of groups of liner are arranged inside the placement groove, the liner is arranged in a columnar structure, a liquid nitrogen freezing chamber is arranged inside the box body, and an inlet is arranged at the upper part of the liquid nitrogen freezing chamber, a sealing cover is arranged at the inlet, and the sealing cover and the inlet are interlocked with each other, a box cover is arranged on the top of the box body, and a sealing block is arranged at the lower part of the box cover, the sealing block and the placement groove are interlocked with each other, a clamping plate is arranged on both sides of the box cover, and a clamping block corresponding to the clamping plate is arranged on both sides of the box body, the bottom of the clamping plate and the clamping block are in contact with each other and clamped, so as to ensure the firmness and sealing of the connection between the box cover and the box body, a telescopic groove matching the inner gear is arranged inside the sealing block, and a spring column is arranged inside the telescopic, a pressing plate is arranged at the lower part of the spring column, and the pressing plate is telescopically connected between the spring column and the telescopic groove, and the pressing plate is in contact with the top of the stem cell test tube.

[0006] As a preferred embodiment of the utility model, an elastic ring is arranged inside the inner container and the elastic ring is arranged in a conical structure.

[0007] As a preferred embodiment of the present invention, a temperature sensor is arranged inside the placement groove and a digital display is arranged on the surface of the box, and the digital display is electrically connected to the temperature sensor.

[0008] As a preferred embodiment of the present invention, protective pads are provided on both sides of the box body and are fixedly connected to the box body.

[0009] As a preferred embodiment of the present invention, a base is provided at the bottom of the box body and the base is fixedly connected to the box body, and the base is made of elastic material.

[0010] As a preferred embodiment of the present utility model, the clamping block is arranged in a trapezoidal structure and the side surfaces of the clamping plate are provided with oblique edges of the clamping blocks corresponding to each other.

[0011] As a preferred embodiment of the present utility model, a groove is provided inside the box cover and a handle is provided inside the groove, and the handle is rotatably connected to the groove.

[0012] Compared with the prior art, the beneficial effects of the utility model are as follows:

[0013] The utility model is provided with a placement groove inside the box body, and a plurality of groups of inner liner are provided inside the placement groove, and the inner liner is provided with a columnar structure, which is convenient for placing the stem cell test tube; a liquid nitrogen freezing chamber is provided inside the box body, and an entrance is provided at the upper part of the liquid nitrogen freezing chamber, and a sealing cover is provided at the entrance, which is convenient for adding liquid nitrogen, and liquid nitrogen can be added in time during the transportation process, so as to ensure the freezing storage time; a box cover is provided on the top of the box body, and a sealing block is provided at the lower part of the box cover, and the sealing block and the placement groove are interlocked, and this arrangement ensures that the box In order to improve the sealing of the box body, clamping plates are arranged on both sides of the box cover and corresponding clamping blocks are arranged on both sides of the box body. During installation, the clamping plates and the bottoms of the clamping blocks are in contact with each other to achieve clamping, thereby ensuring the firmness and sealing of the connection between the box cover and the box body. A telescopic groove matching the inner gear is arranged inside the sealing block, and a spring column is arranged inside the telescopic groove. A pressing plate is arranged at the lower part of the spring column and the pressing plate is telescopically connected between the spring column and the telescopic groove. The pressing plate is in contact with the top of the stem cell test tube. This arrangement ensures the stability and safety of the installation of the stem cell test tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0015] Figure 2 This is a schematic diagram of the front view structure of the utility model;

[0016] Figure 3 This is a side view of the structure of the utility model;

[0017] Figure 4 It is a schematic diagram of the cross-sectional structure of the utility model.

[0018] In the figure: 1. box body; 2. placement slot; 3. box cover; 4. groove; 5. handle; 6. clamp block; 7. clamping plate; 8. anti-slip pad; 9. digital display; 10. sealing block; 11. base; 12. entrance; 13. sealing cover; 14. liquid nitrogen freezing chamber; 15. liner; 16. elastic ring; 17. temperature sensor; 18. telescopic slot; 19. pressure plate; 20. spring column. DETAILED DESCRIPTION

[0019] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0020] See also Figure 1-4The utility model provides a technical solution: a freezing box for cryopreservation of stem cells, comprising: a box body 1, a placement slot 2 is arranged inside the box body 1, and a plurality of groups of liner 15 are arranged inside the placement slot 2, and the liner 15 is arranged in a columnar structure, a liquid nitrogen freezing chamber 14 is arranged inside the box body 1, and an inlet 12 is arranged on the upper part of the liquid nitrogen freezing chamber 14, a sealing cover 13 is arranged at the inlet 12, and the sealing cover 13 and the inlet 12 are mutually embedded, a box cover 3 is arranged on the top of the box body 1, and a sealing block 10 is arranged at the lower part of the box cover 3, and the sealing block 10 and the placement slot 2 are connected. The box cover 3 is interlocked with each other, and the two sides of the box body 1 are provided with a card block 6 corresponding thereto, and the card plate 7 and the bottom of the card block 6 are in contact with each other and are connected to each other, thereby ensuring the firmness and sealing of the connection between the box cover 3 and the box body 1. The interior of the sealing block 10 is provided with a telescopic groove 18 that matches the inner gear, and a spring column 20 is provided inside the telescopic groove. A pressing plate 19 is provided at the lower part of the spring column 20, and the pressing plate 19 is telescopically connected between the spring column 20 and the telescopic groove 18. The pressing plate 19 contacts the top of the stem cell test tube, and a placement is provided inside the box body 1. The box 1 is provided with a plurality of inner tanks 15, the inner tanks 15 are arranged in a columnar structure, which is convenient for placing the stem cell test tubes. A liquid nitrogen freezing chamber 14 is arranged inside the box 1, and an inlet 12 is arranged on the upper part of the liquid nitrogen freezing chamber 14. A sealing cover 13 is arranged at the inlet 12. This arrangement is convenient for adding liquid nitrogen. Liquid nitrogen can be added in time during the transportation process, so as to ensure the freezing storage time. A box cover 3 is arranged on the top of the box 1, and a sealing block 10 is arranged at the lower part of the box cover 3. The sealing block 10 and the placement slot 2 are mutually embedded. This arrangement ensures the sealing of the box 1. Snap-on plates 7 are provided on both sides of the cover 3 and snap-on blocks 6 corresponding thereto are provided on both sides of the box body 1. During installation, the snap-on plates 7 and the bottom of the snap-on blocks 6 are in contact with each other to achieve snap connection, thereby ensuring the firmness and sealing of the connection between the box cover 3 and the box body 1. A telescopic groove 18 matching the inner gear is provided inside the sealing block 10, and a spring column 20 is provided inside the telescopic groove. A pressing plate 19 is provided at the lower part of the spring column 20, and the pressing plate 19 is telescopically connected to the telescopic groove 18 through the spring column 20, and the pressing plate 19 is in contact with the top of the stem cell test tube. This arrangement ensures the stability and safety of the installation of the stem cell test tube.

[0021] Further improvements, such as Figure 4 As shown: the inner part of the inner container 15 is provided with an elastic ring 16 and the elastic ring 16 is arranged in a conical structure, which is convenient for the installation of the stem cell test tube and ensures stability.

[0022] Further improvements, such as Figure 1 , 4As shown: a temperature sensor 17 is arranged inside the placement slot 2 and a digital display 9 is arranged on the surface of the box body 1. The digital display 9 is electrically connected to the temperature sensor 17. This arrangement can monitor the temperature in the placement slot 2 and display it through the digital display 9, which is convenient for external personnel to observe.

[0023] Further improvements, such as Figure 1 As shown: protective pads 8 are arranged on both sides of the box body 1 and the protective pads 8 are fixedly connected to the box body 1. This arrangement reduces temperature transfer and provides a certain thermal insulation performance.

[0024] Further improvements, such as Figure 2 As shown: a base 11 is arranged at the bottom of the box 1 and the base 11 is fixedly connected to the box 1. The base 11 is made of elastic material. This arrangement ensures the stability of the box 1.

[0025] Further improvements, such as Figure 2 As shown, the block 6 is arranged in a trapezoidal structure and the side surfaces of the clamping plate 7 are provided with oblique edges corresponding to each other of the block 6 , which facilitates the clamping portion to slide into the bottom of the block 6 .

[0026] Further improvements, such as Figure 1 As shown: a groove 4 is provided inside the box cover 3 and a handle 5 is provided inside the groove 4. The handle 5 is rotatably connected to the groove 4. This arrangement facilitates the lifting and placing of the box body 1.

[0027] The utility model is provided with a placement groove 2 inside the box body 1 and a plurality of groups of liner 15 are provided inside the placement groove 2. The liner 15 is provided in a columnar structure, which is convenient for placing the stem cell test tube. A liquid nitrogen freezing chamber 14 is provided inside the box body 1 and an inlet 12 is provided on the upper part of the liquid nitrogen freezing chamber 14. A sealing cover 13 is provided at the inlet 12. This arrangement is convenient for adding liquid nitrogen. Liquid nitrogen can be added in time during the transportation process, thereby ensuring the freezing storage time. A box cover 3 is provided on the top of the box body 1 and a sealing block 10 is provided at the lower part of the box cover 3. The sealing block 10 and the placement groove 2 are interlocked with each other. This arrangement ensures that the box In order to improve the sealing performance of the box body 1, snap-on plates 7 are arranged on both sides of the box cover 3 and corresponding snap-on blocks 6 are arranged on both sides of the box body 1. During installation, the snap-on plates 7 and the bottom of the snap-on blocks 6 are in contact with each other to achieve snap connection, thereby ensuring the firmness and sealing performance of the connection between the box cover 3 and the box body 1. A telescopic groove 18 matching the inner gear is arranged inside the sealing block 10, and a spring column 20 is arranged inside the telescopic groove. A pressing plate 19 is arranged at the lower part of the spring column 20, and the pressing plate 19 is telescopically connected to the telescopic groove 18 through the spring column 20, and the pressing plate 19 is in contact with the top of the stem cell test tube. This arrangement ensures the stability and safety of the installation of the stem cell test tube.

[0028] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It is obvious to those skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic features of the present invention. Therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the present invention is defined by the attached claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims are included in the present invention. Any figure mark in the claims should not be regarded as limiting the claims involved.

[0029] Finally, a few points should be explained: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, and can be mechanical or electrical connections, or internal connectivity between two components, or direct connections. "Up", "down", "left", "right", etc. are only used to indicate relative position relationships. When the absolute position of the object being described changes, the relative position relationship may change.

[0030] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A freezing box for cryopreservation of stem cells, characterized in that: include: A box body (1), wherein a placement groove (2) is arranged inside the box body (1), and a plurality of groups of inner liner (15) are arranged inside the placement groove (2), and the inner liner (15) is arranged in a columnar structure. A liquid nitrogen freezing chamber (14) is arranged inside the box body (1), and an inlet (12) is arranged at the top of the liquid nitrogen freezing chamber (14), and a sealing cover (13) is arranged at the inlet (12), and the sealing cover (13) and the inlet (12) are interlocked with each other. A box cover (3) is arranged at the top of the box body (1), and a sealing block (10) is arranged at the bottom of the box cover (3), and the sealing block (10) and the placement groove (2) are interlocked with each other. The box cover (3) is provided with a clamping plate (7) on both sides, and the box body (1) is provided with a clamping block (6) corresponding thereto. The clamping plate (7) and the bottom of the clamping block (6) are in contact with each other and are clamped, thereby ensuring the firmness and sealing of the connection between the box cover (3) and the box body (1). The sealing block (10) is provided with a telescopic groove (18) matching the inner stop, and a spring column (20) is provided inside the telescopic groove. A pressing plate (19) is provided at the lower part of the spring column (20), and the pressing plate (19) is telescopically connected to the telescopic groove (18) through the spring column (20). The pressing plate (19) is in contact with the top of the stem cell test tube.

2. A freezing box for cryopreservation of stem cells according to claim 1, characterized in that: An elastic ring (16) is arranged inside the inner container (15), and the elastic ring (16) is arranged in a conical structure.

3. A freezing box for cryopreservation of stem cells according to claim 1, characterized in that: A temperature sensor (17) is arranged inside the placement groove (2) and a digital display (9) is arranged on the surface of the box body (1), and the digital display (9) is electrically connected to the temperature sensor (17).

4. A freezing box for cryopreservation of stem cells according to claim 1, characterized in that: Protection pads (8) are provided on both sides of the box body (1), and the protection pads (8) are fixedly connected to the box body (1).

5. A freezing box for cryopreservation of stem cells according to claim 1, characterized in that: A base (11) is provided at the bottom of the box body (1), and the base (11) is fixedly connected to the box body (1), and the base (11) is made of an elastic material.

6. A freezing box for cryopreservation of stem cells according to claim 1, characterized in that: The clamping block (6) is arranged in a trapezoidal structure and the side surfaces of the clamping plate (7) are provided with mutually corresponding oblique edges of the clamping block (6).

7. A freezing box for cryopreservation of stem cells according to claim 1, characterized in that: A groove (4) is provided inside the box cover (3), and a handle (5) is provided inside the groove (4), and the handle (5) is rotatably connected to the groove (4).

Images