Constant temperature equipment for cell culture

Abstract

The utility model discloses constant temperature equipment for cell culture, which comprises a constant temperature box, when a cell culture bottle needs to be placed, the cell culture bottle can be directly inserted between two groups of arc-shaped clamping plates which are oppositely arranged, and the cell culture bottle can be conveniently inserted by virtue of outwards turned arc edges which are integrally formed at the tops of the two groups of arc-shaped clamping plates; arc-shaped clamping plates are extruded through cooperation of telescopic rods and springs, so that the cell culture bottle can be stably fixed between the two groups of arc-shaped clamping plates in the placing groove, the clamping and fixing efficiency of the cell culture bottle is improved, and meanwhile, the cell culture bottle is relatively convenient to take out; a heating device and a refrigerating device in the equipment box are matched with a temperature sensor in the constant-temperature box, so that the temperature in the constant-temperature box is kept at a constant temperature which is convenient for cell culture, and a raised strip on the thermal-insulation box door is matched with a sealing groove in the constant-temperature box to seal the joint of the thermal-insulation box door and the constant-temperature box; therefore, the leakage condition in the culture process can be effectively avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of cell culture, in particular to a constant temperature device for cell culture. Background Art

[0002] When culturing cells, it is necessary to ensure that the external temperature is at an appropriate temperature, so a constant temperature device is required.

[0003] For example, a thermostatic device for cell culture (Announcement No.: CN219326779U) includes a main body, a safety disturbance mechanism and a stable clamping mechanism, wherein the safety disturbance mechanism is located above the main body, and the stable clamping mechanism is located in the middle of the main body. The main body includes a fixed base, a support foot, a cell culture thermostatic box, a heat preservation movable door, a culture chamber and a heating plate, wherein the support foot is fixedly mounted at the lower end of the fixed base, and the cell culture thermostatic box is fixedly mounted at the upper end of the fixed base. The thermostatic device for cell culture allows the thermostatic device to be disturbed after the cell culture bottle is fixed, so that the substances in the cell culture bottle can be fully fused. Through the cooperation of the speed reduction driven gear and the transmission gear, the cell culture bottle can be disturbed more gently, avoiding the influence of the violent disturbance of the cell culture bottle on the culture result, and the culture effect is good and the practicality of use is high.

[0004] Based on the search of the above patents and in combination with the equipment in the prior art, it is found that when the above equipment clamps and fixes the cell culture bottle, it is necessary to first open the two sets of clamping plates that are relatively set in sequence, and then place the cell culture bottle between the two sets of clamping plates. When there are too many cell culture bottles, it takes a lot of time and there is a problem of inconvenience in clamping and fixing the cell culture bottle. Therefore, we need to propose a constant temperature device for cell culture. Utility Model Content

[0005] The utility model aims to provide a constant temperature device for cell culture, which has the advantage of improving the clamping and fixing efficiency of cell culture bottles, so as to solve the problems raised in the above-mentioned background technology.

[0006] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0007] A constant temperature device for cell culture, comprising a constant temperature box, one side of the constant temperature box is hinged with an incubator door by a hinge, the bottom of the constant temperature box is fixedly connected with an equipment box, the inside of the equipment box is installed with a heating device and a cooling device for maintaining a constant temperature inside the constant temperature box, the heating device is composed of a mounting seat and a heating pipe, the cooling device is composed of a compressor, an evaporator and a condenser, and the bottom of the constant temperature box is provided with a ventilation mesh slot communicating with the inside of the equipment box;

[0008] A placement mechanism for placing cell culture bottles is rotatably installed inside the constant temperature box, and the placement mechanism includes a rotating rod, and the two ends of the rotating rod are rotatably installed on the inner top and inner bottom of the constant temperature box respectively, and the top of the rotating rod passes through the constant temperature box and is fixedly connected to a reduction motor, and three groups of discharge trays are fixedly installed at equal intervals on the outer wall of the rotating rod, and the surface of the discharge tray is provided with six groups of placement grooves in a circular array, and a clamping assembly for clamping and fixing the cell culture bottle is arranged inside the placement groove.

[0009] Preferably, the clamping assembly includes two groups of arc-shaped clamps, and the two groups of arc-shaped clamps are correspondingly movably installed inside the placement groove. Two groups of telescopic rods are fixedly installed on one side of the two groups of arc-shaped clamps, one end of the two groups of telescopic rods is fixedly connected to the inner wall of the placement groove, and the outer wall of the telescopic rod is provided with a spring.

[0010] Preferably, the tops of the two groups of arc-shaped splints are integrally formed with outward-turned arc edges for facilitating the insertion of cell culture bottles, and the outward-turned arc edges at the tops of the two groups of arc-shaped splints are trumpet-shaped.

[0011] Preferably, the inner wall of the placement groove is symmetrically provided with four groups of installation grooves, and one ends of the four groups of telescopic rods are respectively fixedly installed inside the four groups of installation grooves.

[0012] Preferably, a partition is fixedly installed at the center of the interior of the equipment box, the heating device and the cooling device are respectively located on both sides of the partition, and a ventilation slot is provided on the side of the equipment box located on the cooling device.

[0013] Preferably, the top of the thermostatic box is fixedly connected to an exhaust pipe, and an exhaust valve is provided on the outer wall of the exhaust pipe.

[0014] Preferably, a temperature sensor is fixedly installed on the inner top of the constant temperature box, an observation window is opened on the door of the insulated box, and a control panel is fixedly installed on the insulated box door on one side of the observation window.

[0015] Preferably, a sealing groove is provided on one side of the thermostatic box door, and a raised strip matching the sealing groove is fixedly installed on one side of the thermostatic box door, and the raised strip abuts against the inside of the sealing groove.

[0016] Compared with the prior art, the beneficial effects of the utility model are:

[0017] 1. The utility model cooperates with two groups of arc-shaped clamping plates in the clamping assembly. When a cell culture bottle needs to be placed, the cell culture bottle can be directly inserted between the two groups of arc-shaped clamping plates arranged opposite to each other. The outward-turned arc edges formed integrally on the tops of the two groups of arc-shaped clamping plates can facilitate the insertion of the cell culture bottle. The arc-shaped clamping plates are squeezed by the cooperation of the telescopic rod and the spring, so that the cell culture bottle can be stably fixed between the two groups of arc-shaped clamping plates in the placement groove, which has the advantage of improving the clamping and fixing efficiency of the cell culture bottle, and the cell culture bottle can also be taken out more conveniently;

[0018] 2. The heating device and refrigeration device in the equipment box cooperate with the temperature sensor in the constant temperature box to keep the temperature in the constant temperature box at a constant temperature that is convenient for cell culture. The raised strip on the incubator door cooperates with the sealing groove on the incubator to seal the connection between the incubator door and the constant temperature box, thereby increasing the sealing effect of the incubator door after closing and the closed part of the constant temperature box, thereby effectively avoiding leakage during the culture process. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a three-dimensional structural schematic diagram of the utility model;

[0020] Figure 2 It is a schematic diagram of the structure inside the thermostatic box and the equipment box of the utility model;

[0021] Figure 3 It is a structural schematic diagram of the placement mechanism of the utility model;

[0022] Figure 4 It is a structural schematic diagram of the placement groove and clamping components on the surface of the discharge tray of the utility model.

[0023] In the figure: 1. Constant temperature box; 2. Insulation box door; 3. Equipment box; 4. Heating device; 5. Refrigeration device; 6. Ventilation mesh slot; 7. Placement mechanism; 71. Rotating rod; 72. Speed ​​reduction motor; 73. Discharge tray; 74. Placement slot; 75. Clamping assembly; 751. Arc clamping plate; 752. Telescopic rod; 753. Spring; 754. Installation slot; 8. Temperature sensor; 9. Exhaust pipe; 10. Partition; 11. Ventilation slot; 12. Observation window; 13. Control panel; 14. Sealing slot. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] See also Figure 1-4 , the utility model provides a technical solution:

[0026] A constant temperature device for cell culture, comprising a constant temperature box 1, a heat preservation box door 2 is hingedly connected to one side of the constant temperature box 1 by a hinge, an equipment box 3 is fixedly connected to the bottom of the constant temperature box 1, a heating device 4 and a refrigeration device 5 for maintaining a constant temperature inside the constant temperature box 1 are installed inside the equipment box 3, the heating device 4 is composed of a mounting seat and a heating pipe, the refrigeration device 5 is composed of a compressor, an evaporator and a condenser, and a ventilation mesh slot 6 communicating with the inside of the equipment box 3 is opened at the bottom of the constant temperature box 1;

[0027] A placement mechanism 7 for placing cell culture bottles is rotatably installed inside the constant temperature box 1. The placement mechanism 7 includes a rotating rod 71. The two ends of the rotating rod 71 are rotatably installed on the inner top and inner bottom of the constant temperature box 1 respectively, and the top of the rotating rod 71 passes through the constant temperature box 1 and is fixedly connected to a reduction motor 72. Three groups of discharge trays 73 are fixedly installed at equal intervals on the outer wall of the rotating rod 71. The surface of the discharge tray 73 is provided with six groups of placement grooves 74 in a circular array. A clamping assembly 75 for clamping and fixing the cell culture bottle is arranged inside the placement groove 74.

[0028] The clamping assembly 75 includes two groups of arc-shaped splints 751, which are movably installed in correspondence inside the placement groove 74. Two groups of telescopic rods 752 are fixedly installed on one side of the two groups of arc-shaped splints 751. One end of the two groups of telescopic rods 752 is fixedly connected to the inner wall of the placement groove 74, and the outer wall of the telescopic rod 752 is sleeved with a spring 753, which facilitates the arc-shaped splint 751 to be squeezed by the cooperation of the telescopic rod 752 and the spring 753, so that the cell culture bottle can be stably fixed between the two groups of arc-shaped splints 751 in the placement groove 74.

[0029] The tops of the two sets of arc splints 751 are integrally formed with outward arc edges for easy insertion of cell culture bottles. The outward arc edges of the tops of the two sets of arc splints 751 are trumpet-shaped, which is convenient for inserting cell culture bottles and also makes it easier and quicker to remove cell culture bottles.

[0030] The inner wall of the placement groove 74 is symmetrically provided with four groups of installation grooves 754, and one end of the four groups of telescopic rods 752 are respectively fixedly installed inside the four groups of installation grooves 754, so as to facilitate the arc-shaped clamping plate 751 to avoid the telescopic rods 752 and springs 753 when they are squeezed by force, thereby reducing the space occupied by the telescopic rods 752 and springs 753 in the placement groove 74.

[0031] A partition 10 is fixedly installed at the center of the interior of the equipment box 3, and the heating device 4 and the refrigeration device 5 are respectively located on both sides of the partition 10. The equipment box 3 is divided by the partition 10, and a ventilation slot 11 is provided on one side of the equipment box 3 located at the refrigeration device 5 to facilitate ventilation of the refrigeration device 5 in the equipment box 3.

[0032] The top of the thermostatic box 1 is fixedly connected with an exhaust pipe 9, and the outer wall of the exhaust pipe 9 is provided with an exhaust valve, so as to exhaust the inside of the thermostatic box 1 through the exhaust pipe 9 and keep the air pressure inside the thermostatic box 1 stable.

[0033] A temperature sensor 8 is fixedly installed on the inner top of the constant temperature box 1, an observation window 12 is opened on the incubator door 2, and a control panel 13 is fixedly installed on the incubator door 2 on one side of the observation window 12. The control panel 13 is electrically connected to the heating device 4, the refrigeration device 5, the reduction motor 72, the temperature sensor 8 and the exhaust valve through wires.

[0034] A sealing groove 14 is provided on one side of the thermostatic box door 2 of the thermostatic box 1 . A raised strip matching the sealing groove 14 is fixedly installed on one side of the thermostatic box door 2 . The raised strip abuts against the inside of the sealing groove 14 .

[0035] Working principle: When the utility model is used, the cell culture bottle can be directly inserted between the two groups of arc-shaped clamping plates 751 arranged opposite to each other. The outward arc edge formed integrally on the top of the two groups of arc-shaped clamping plates 751 can facilitate the insertion of the cell culture bottle. The arc-shaped clamping plates 751 are squeezed by the cooperation of the telescopic rod 752 and the spring 753, so that the cell culture bottle can be stably fixed between the two groups of arc-shaped clamping plates 751 in the placement groove 74. The cell culture bottle is sequentially placed in the clamping assembly 75 in the placement groove 74, so that the placement grooves 74 on the surfaces of the three groups of discharge trays 73 in the placement mechanism 7 are filled, and the connection between the insulation box door 2 and the constant temperature box 1 is sealed by the raised strip on the insulation box door 2 and the sealing groove 14 on the constant temperature box 1;

[0036] The heating device 4 and the cooling device 5 in the equipment box 3 are controlled by the control panel 13, so that the heating device 4 and the cooling device 5 cooperate with the temperature sensor 8 in the constant temperature box 1 to keep the temperature in the constant temperature box 1 at a constant temperature that is convenient for cell culture. The output shaft of the reduction motor 72 in the placement mechanism 7 drives the rotating rod 71 to rotate slowly, so that the cell culture bottles clamped and fixed on the three groups of discharge trays 73 on the outer wall of the rotating rod 71 are disturbed with appropriate force.

[0037] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A constant temperature device for cell culture, comprising a constant temperature box (1), characterized in that: A heat preservation box door (2) is hingedly connected to one side of the thermostatic box (1), and a device box (3) is fixedly connected to the bottom of the thermostatic box (1). A heating device (4) and a refrigeration device (5) for maintaining a constant temperature inside the thermostatic box (1) are installed inside the device box (3). The heating device (4) is composed of a mounting seat and a heating pipe, and the refrigeration device (5) is composed of a compressor, an evaporator and a condenser. A ventilation mesh groove (6) communicating with the inside of the device box (3) is provided at the bottom of the thermostatic box (1); A placement mechanism (7) for placing a cell culture bottle is rotatably installed inside the thermostatic box (1), and the placement mechanism (7) comprises a rotating rod (71), the two ends of the rotating rod (71) are rotatably installed on the inner top and inner bottom of the thermostatic box (1), and the top of the rotating rod (71) passes through the thermostatic box (1) and is fixedly connected to a reduction motor (72), three groups of discharge trays (73) are fixedly installed at equal intervals on the outer wall of the rotating rod (71), and the surface of the discharge tray (73) is provided with six groups of placement grooves (74) in a circular array, and a clamping assembly (75) for clamping and fixing the cell culture bottle is arranged inside the placement groove (74).

2. A constant temperature device for cell culture according to claim 1, characterized in that: The clamping assembly (75) comprises two groups of arc-shaped clamping plates (751), the two groups of arc-shaped clamping plates (751) are correspondingly movably mounted inside the placement groove (74), two groups of telescopic rods (752) are fixedly mounted on one side of the two groups of arc-shaped clamping plates (751), one end of the two groups of telescopic rods (752) is fixedly connected to the inner wall of the placement groove (74), and the outer wall of the telescopic rod (752) is provided with a spring (753).

3. A constant temperature device for cell culture according to claim 2, characterized in that: The tops of the two groups of arc-shaped splints (751) are integrally formed with outward-turned arc edges for facilitating the insertion of cell culture bottles, and the outward-turned arc edges at the tops of the two groups of arc-shaped splints (751) are arranged in a trumpet shape.

4. A constant temperature device for cell culture according to claim 3, characterized in that: The inner wall of the placement groove (74) is symmetrically provided with four groups of installation grooves (754), and one end of the four groups of telescopic rods (752) is respectively fixedly installed inside the four groups of installation grooves (754).

5. A constant temperature device for cell culture according to claim 1, characterized in that: A partition (10) is fixedly installed at the center of the interior of the equipment box (3), the heating device (4) and the refrigeration device (5) are respectively located on both sides of the partition (10), and a ventilation slot (11) is provided on the side of the equipment box (3) located on the refrigeration device (5).

6. A constant temperature device for cell culture according to claim 1, characterized in that: The top of the thermostatic box (1) is fixedly connected to an exhaust pipe (9), and an exhaust valve is provided on the outer wall of the exhaust pipe (9).

7. A constant temperature device for cell culture according to claim 1, characterized in that: A temperature sensor (8) is fixedly mounted on the inner top of the thermostatic box (1); an observation window (12) is provided on the thermostatic box door (2); and a control panel (13) is fixedly mounted on the thermostatic box door (2) on one side of the observation window (12).

8. A constant temperature device for cell culture according to claim 1, characterized in that: The thermostatic box (1) is provided with a sealing groove (14) on one side of the insulation box door (2), and a raised strip matching the sealing groove (14) is fixedly installed on one side of the insulation box door (2), and the raised strip abuts against the inside of the sealing groove (14).

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