Production device of gamma cyclodextrin

Abstract

The utility model belongs to the technical field of cyclodextrin production, and particularly relates to a gamma cyclodextrin production device which comprises a reaction kettle and a distillation tower connected with the reaction kettle through a pipeline, the top of the reaction kettle is provided with a feed port and an additive port, a stirrer is arranged in the reaction kettle, and the top of the stirrer penetrates through the top of the reaction kettle and is provided with a motor. A material suction disc is arranged at the lower part of the inner side of the reaction kettle, a discharge pipe is arranged on the inner wall of the reaction kettle, a material suction pump positioned outside the reaction kettle is connected onto the material suction disc, the material suction pump is connected with a buffer tank, the bottom of the buffer tank is connected with the discharge pipe, a filter screen is arranged in the buffer tank, and a filter is arranged on a pipeline between the reaction kettle and the distillation tower. According to the utility model, complexes generated in the production process of gamma cyclodextrin can be separated, the complexes generated in a reaction system can be effectively collected through the structure of the suction disc, the contact area between the complexes and gamma cyclodextrin is reduced, and the yield and the product quality of gamma cyclodextrin are improved.

Description

Technical Field

[0001] The utility model belongs to the technical field of cyclodextrin production, and specifically relates to a production device for gamma cyclodextrin. Background Art

[0002] Gamma cyclodextrin is a non-reducing cyclic sugar. It is formed by the conversion of starch into 8 glucose units through cyclodextrin glucosyltransferase and then cyclized into D-pyranose units connected by α-1,4-bonds. Adding chemical additives during the conversion process can improve the conversion rate. Gamma cyclodextrin has a high solubility in water, and a larger cavity structure is formed in the gamma cyclodextrin molecule, which makes gamma cyclodextrin suitable for inclusion of larger molecular groups in water. Its larger cavity structure gives gamma cyclodextrin excellent inclusion capacity and can include a wider range of guest molecules.

[0003] Therefore, gamma cyclodextrin is often used as a pharmaceutical excipient and food additive, but the chemical additives added during the preparation process will form insoluble matter with the partially converted gamma cyclodextrin. The traditional conversion reaction is completed in the reactor and then processed. The insoluble matter formed will always exist in the reactor, which is likely to cause further degradation of gamma cyclodextrin, reduce the conversion rate of gamma cyclodextrin, and the impurity content in the product is high. Utility Model Content

[0004] In view of the above deficiencies in the prior art, the technical problem to be solved by the utility model is: to provide a production device for gamma cyclodextrin, which can separate the complex produced during production and improve the purity and product quality of gamma cyclodextrin.

[0005] The technical solution adopted by the utility model to solve its technical problems is:

[0006] The production device of gamma cyclodextrin described in the utility model comprises a reactor and a distillation tower connected to the reactor by a pipeline, a feed inlet and an auxiliary agent inlet are provided on the top of the reactor, an agitator is arranged inside the reactor, a motor is arranged on the top of the agitator and penetrates through the top of the reactor, a suction plate is arranged at the lower part of the inner side of the reactor, a discharge pipe is arranged on the inner wall of the reactor, a suction pump located outside the reactor is connected to the suction plate, the suction pump is connected to a buffer tank, the bottom of the buffer tank is connected to the discharge pipe, a filter screen is arranged in the buffer tank, and a filter is arranged on the pipeline between the reactor and the distillation tower.

[0007] in:

[0008] The reactor is provided with a jacket outside, a water inlet is provided at the lower part of the jacket, and a water outlet is provided at the upper part of the jacket.

[0009] The discharge pipe is vertically arranged on the inner wall of the reaction kettle, and a plurality of through holes are arranged on the discharge pipe.

[0010] The suction plate is integrally arranged to match the inner bottom surface of the reaction kettle, the top of the suction plate is screen mesh 1, and the bottom of the suction plate is screen mesh 2.

[0011] The aperture size of the screen one is larger than the aperture size of the screen two.

[0012] The suction pump is connected to the upper part of the side wall of the buffer tank, and the connection between the suction pump and the buffer tank is located above the filter net.

[0013] The aperture size of the filter screen is smaller than the aperture size of the second screen screen.

[0014] The bottom of the buffer tank is funnel-shaped, and the center of the bottom of the buffer tank is connected to the discharge pipe.

[0015] The bottom of the distillation tower is connected with a storage tank through a pipeline.

[0016] The bottom of the filter is arranged in a funnel shape, and a filter outlet is arranged at the center of the bottom.

[0017] The beneficial effects of the utility model are:

[0018] The utility model can separate the complex generated in the production process of gamma-cyclodextrin by arranging structures such as a suction plate and a discharge pipe in a reactor, thereby avoiding affecting the purity of the gamma-cyclodextrin. The structure of the suction plate can effectively collect the complex generated in the reaction system, reduce the contact area between the complex and the gamma-cyclodextrin, and can reduce the amount of the gamma-cyclodextrin solution sucked by the suction pump when separating the complex, thereby minimizing the decomposition of the gamma-cyclodextrin. The filter screen in the buffer tank can separate the sucked gamma-cyclodextrin solution from the complex, and re-transport the gamma-cyclodextrin solution back to the reactor, thereby improving the yield and product quality of the gamma-cyclodextrin. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the structure of the utility model;

[0020] Figure 2 It is a structural schematic diagram of the suction plate in the utility model;

[0021] Figure 3 It is a structural schematic diagram of the screen mesh 1 in the utility model;

[0022] Figure 4 It is a structural schematic diagram of the screen mesh 2 in the utility model;

[0023] Figure 5 It is a structural schematic diagram of the filter screen in the utility model;

[0024] In the figure: 1. Reactor; 2. Jacket; 3. Motor; 4. Agitator; 5. Feed inlet; 6. Auxiliary agent inlet; 7. Discharge pipe; 8. Suction plate; 9. Filter; 10. Distillation tower; 11. Storage tank; 12. Suction pump; 13. Buffer tank; 14. Filter screen; 201. Water inlet; 202. Water outlet; 801. Screen one; 802. Screen two. DETAILED DESCRIPTION

[0025] The embodiments of the present utility model are further described below in conjunction with the accompanying drawings.

[0026] Example 1

[0027] like Figure 1-5 As shown, the production device of gamma cyclodextrin includes a reactor 1 and a distillation tower 10 connected to the reactor 1 by a pipeline, a feed inlet 5 and an auxiliary agent inlet 6 are opened on the top of the reactor 1, a stirrer 4 is arranged inside the reactor 1, a motor 3 is arranged on the top of the stirrer 4 and penetrates through the top of the reactor 1, a suction plate 8 is arranged on the lower inner side of the reactor 1, a discharge pipe 7 is arranged on the inner wall of the reactor 1, a suction pump 12 located outside the reactor 1 is connected to the suction plate 8, the suction pump 12 is connected to a buffer tank 13, the bottom of the buffer tank 13 is connected to the discharge pipe 7, a filter screen 14 is arranged in the buffer tank 13, and a filter 9 is arranged on the pipeline between the reactor 1 and the distillation tower 10.

[0028] The buffer tank 13 can further separate the complex in the gamma-cyclodextrin solution and transport the gamma-cyclodextrin solution back to the reactor 1. The filter 9 can further filter the gamma-cyclodextrin solution to avoid decomposition of the gamma-cyclodextrin solution during distillation.

[0029] A jacket 2 is disposed outside the reactor 1 , a water inlet 201 is disposed at the lower portion of the jacket 2 , and a water outlet 202 is disposed at the upper portion of the jacket 2 .

[0030] The discharge pipe 7 is vertically arranged on the inner wall of the reactor 1, and a plurality of through holes are arranged on the discharge pipe 7. The buffer tank 13 re-transports the solution in the reactor 1, and the solution is dispersed into the reactor 1 through the through holes on the discharge pipe 7 for full reaction.

[0031] The suction plate 8 is integrally arranged to cooperate with the inner bottom surface of the reaction kettle 1 , the top of the suction plate 8 is a screen 1 801 , and the bottom of the suction plate 8 is a screen 2 802 .

[0032] The aperture size of the mesh 1 801 is larger than that of the mesh 2 802. The mesh 1 801 allows the complex in the reaction kettle 1 to enter the suction plate 8 and be intercepted by the mesh 2 802. The suction pump 12 can minimize the discharge of the solution when sucking the complex.

[0033] The suction pump 12 is connected to the upper side wall of the buffer tank 13, and the connection between the suction pump 12 and the buffer tank 13 is located above the filter 14. After the gamma-cyclodextrin solution enters the buffer tank 13, the complex is intercepted by the filter 14, which can improve the purity of the solution.

[0034] The aperture size of the filter screen 14 is smaller than the aperture size of the screen screen 2 802 .

[0035] The bottom of the buffer tank 13 is funnel-shaped, and the center of the bottom of the buffer tank 13 is connected to the discharge pipe 7 .

[0036] The bottom of the distillation tower 10 is connected to a storage tank 11 through a pipeline.

[0037] The bottom of the filter 9 is arranged in a funnel shape, and a filter outlet is arranged at the center of the bottom.

[0038] Working principle and process:

[0039] During production, the starch raw material is transported to the reactor 1 through the feed port 5, cyclodextrin glucosyltransferase is added through the additive port 6 for reaction, the motor 3 is turned on to drive the stirrer 4 for stirring, and then chemical additives are added to promote the conversion of gamma cyclodextrin, the solution condition in the reactor 1 is observed and the suction pump 12 is turned on in time, and the pressure of the suction pump 12 is set to a constant value, so that the complex generated in the solution can be continuously deposited in the suction disk 8 and transported to the buffer tank 13 by the suction pump 12. The filter screen 14 in the buffer tank 13 can intercept the complex, and the remaining gamma cyclodextrin solution is transported back to the reactor 1. After the reaction is completed, the gamma cyclodextrin solution is filtered through the filter 9, and then enters the distillation tower 10 for distillation to obtain a pure gamma cyclodextrin solution, which is stored in the storage tank 11. The separated complex can be recycled and used as a reaction raw material again.

Claims

1. A gamma-cyclodextrin production device, comprising a reactor (1) and a distillation tower (10) connected to the reactor (1) via a pipeline, characterized in that: The reactor (1) is provided with a feed inlet (5) and an auxiliary agent inlet (6) at the top, a stirrer (4) is arranged inside the reactor (1), a motor (3) is arranged at the top of the stirrer (4) penetrating the top of the reactor (1), a suction plate (8) is arranged at the lower part of the inner side of the reactor (1), a discharge pipe (7) is arranged on the inner wall of the reactor (1), the suction plate (8) is connected to a suction pump (12) located outside the reactor (1), the suction pump (12) is connected to a buffer tank (13), the bottom of the buffer tank (13) is connected to the discharge pipe (7), a filter screen (14) is arranged in the buffer tank (13), and a filter (9) is arranged on the pipeline between the reactor (1) and the distillation tower (10).

2. The production device of gamma-cyclodextrin according to claim 1, characterized in that: A jacket (2) is arranged outside the reaction kettle (1); a water inlet (201) is arranged at the lower part of the jacket (2); and a water outlet (202) is arranged at the upper part of the jacket (2).

3. The production device of gamma-cyclodextrin according to claim 1, characterized in that: The discharge pipe (7) is vertically arranged on the inner wall of the reaction kettle (1), and a plurality of through holes are arranged on the discharge pipe (7).

4. The production device of gamma-cyclodextrin according to claim 1, characterized in that: The suction plate (8) is integrally arranged to match the inner bottom surface of the reaction kettle (1); the top of the suction plate (8) is screen mesh 1 (801), and the bottom of the suction plate (8) is screen mesh 2 (802).

5. The production device of gamma-cyclodextrin according to claim 4, characterized in that: The aperture size of the screen one (801) is larger than the aperture size of the screen two (802).

6. The production device of gamma-cyclodextrin according to claim 1, characterized in that: The suction pump (12) is connected to the upper part of the side wall of the buffer tank (13), and the connection between the suction pump (12) and the buffer tank (13) is located above the filter screen (14).

7. The production device of gamma-cyclodextrin according to claim 5, characterized in that: The pore size of the filter screen (14) is smaller than the pore size of the second screen screen (802).

8. The production device of gamma-cyclodextrin according to claim 1, characterized in that: The bottom of the buffer tank (13) is funnel-shaped, and the center of the bottom of the buffer tank (13) is connected to the discharge pipe (7).

9. The production device of gamma-cyclodextrin according to claim 1, characterized in that: The bottom of the distillation tower (10) is connected to a storage tank (11) via a pipeline.

10. The production device of gamma-cyclodextrin according to claim 1, characterized in that: The bottom of the filter (9) is arranged in a funnel shape, and a filter outlet is arranged at the center of the bottom.

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