Energy-saving type solid-phase extraction column blow-drying device

Abstract

The utility model provides an energy-saving solid-phase extraction column blow-drying device, which relates to the technical field of solid-phase extraction devices and comprises a nitrogen source, a gas diverter and a plurality of blow-drying components. The nitrogen source is connected with the gas flow divider, a plurality of flow divider gas outlets are formed in the gas flow divider, and the blow-drying assembly comprises a gas blowing pipe and a solid-phase extraction column; an air inlet plug is arranged at the air inlet end of the solid-phase extraction column, an air guide pipe is axially arranged on the air inlet plug, one end of an air blowing pipe is connected with an air outlet of the flow divider, the other end of the air blowing pipe is connected with the air guide pipe, and an air pressure regulating valve is arranged on the air blowing pipe. The device has the beneficial effects that the gas inlet plug of the device can seal the gas inlet of the solid-phase extraction column, and the gas pressure regulating valve can regulate the gas inlet amount of the solid-phase extraction column, so that the flow of nitrogen blown by a nitrogen source through the gas guide pipe meets the nitrogen blow-drying requirement, the nitrogen is prevented from overflowing, and the service life of the solid-phase extraction column is prolonged. Therefore, the nitrogen blow-drying efficiency is improved, and the nitrogen consumption in the nitrogen blow-drying process is reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of solid phase extraction devices, in particular to an energy-saving solid phase extraction column drying device. Background Art

[0002] Solid-Phase Extraction (SPE) is a sample pretreatment technology developed in recent years. It is developed by combining liquid-solid extraction columns and liquid chromatography technology. It is mainly used for sample separation, purification and concentration. Compared with traditional liquid-liquid extraction, solid-phase extraction can improve the recovery rate of analytes, more effectively separate analytes from interfering components, reduce sample pretreatment processes, and is simple to operate, time-saving and labor-saving.

[0003] Solid phase extraction requires nitrogen blowing to dry the solid phase extraction column, that is, nitrogen needs to be continuously introduced into the solid phase extraction column to blow dry part of the solvent in the solid phase extraction column. The traditional method of use is to directly use a nitrogen source (usually a nitrogen bottle) to blow dry the solid phase extraction column through a blowing tube. Since the air inlet end of the solid phase extraction column is not closed, the nitrogen blowing process is prone to nitrogen leakage and the nitrogen flow rate into the solid phase extraction column cannot be adjusted, which will lead to nitrogen waste and a long nitrogen blowing process. Utility Model Content

[0004] In view of this, in order to reduce the nitrogen waste and time-consuming problem in the nitrogen drying process of solid phase extraction column, the utility model provides an energy-saving solid phase extraction column drying device, including a nitrogen source, a gas splitter and a plurality of drying components;

[0005] The nitrogen source is connected to the gas splitter, a plurality of splitter gas outlets are provided on the gas splitter, and the drying assembly includes a blow pipe and a solid phase extraction column;

[0006] The air inlet end of the solid phase extraction column is provided with an air inlet plug, which is fixed to the air inlet end of the solid phase extraction column by a buckle assembly, and the air inlet plug is axially provided with an air guide tube, one end of which is located in the solid phase extraction column, and the other end of which passes through the air inlet plug and extends to the outside of the solid phase extraction column;

[0007] One end of the air blowing pipe is connected to the air outlet of the diverter, and the other end is connected to the air guide pipe. An air pressure regulating valve is arranged on the air blowing pipe.

[0008] Furthermore, the nitrogen source and the gas diverter are connected via a gas pipeline, and a pressure reducing valve is provided on the gas pipeline.

[0009] Furthermore, each of the air blowing pipes is also provided with an air pressure gauge.

[0010] Furthermore, both ends of the air blowing pipe are provided with C-type quick connectors, and the air blowing pipe is connected to the air outlet of the diverter and the air guide pipe through the C-type quick connectors.

[0011] Furthermore, the air inlet plug includes a connecting plate and a conical plug body connected to a surface of the connecting plate, wherein the thicker end of the conical plug body is connected to the connecting plate, and the thinner end of the conical plug body extends into the solid phase extraction column, and the connecting plate is fixed to the air inlet end of the solid phase extraction column by a snap assembly.

[0012] Furthermore, the air inlet plug and the air guide pipe are both made of transparent PP plastic material and are integrally formed.

[0013] Furthermore, a connecting skirt is provided at the edge of the air inlet end of the solid phase extraction column, the edge of the connecting piece is attached to the connecting skirt, and the buckle assembly clamps the connecting piece and the connecting skirt.

[0014] Furthermore, the buckle assembly includes two half-ring buckles, which are closed to form a circular ring structure. Each half-ring buckle includes an upper clamping plate and a lower clamping plate whose outer edges are connected together. The upper clamping plate and the lower clamping plate are respectively located on the upper side of the connecting plate and the lower side of the connecting skirt, thereby clamping the connecting plate and the connecting skirt.

[0015] Furthermore, the two half-ring buckles are both made of stainless steel.

[0016] Furthermore, a threaded boss is provided on the lower surface of the lower clamping plate, a locking threaded hole penetrating the lower clamping plate is provided in the threaded boss, a locking screw is provided in the locking threaded hole, and the end of the locking screw presses the connecting skirt upward.

[0017] The utility model discloses an energy-saving solid phase extraction column drying device with beneficial effects as follows: the solid phase extraction column drying device comprises a nitrogen source, a gas diverter and a plurality of drying components; the nitrogen source is connected to the gas diverter, a plurality of diverter gas outlets are arranged on the gas diverter, and the drying components comprise a gas blowing pipe and a solid phase extraction column; an inlet plug is arranged at the gas inlet end of the solid phase extraction column, an air guide pipe is arranged axially on the inlet plug, one end of the gas blowing pipe is connected to the diverter gas outlet, and the other end is connected to the air guide pipe, and an air pressure regulating valve is arranged on the gas blowing pipe, wherein the inlet plug can close the gas inlet of the solid phase extraction column, and the air pressure regulating valve can adjust the gas intake of the solid phase extraction column, so as to ensure that the nitrogen flow rate blown in by the nitrogen source through the air guide pipe meets the nitrogen drying needs, avoid nitrogen overflow, thereby improving the nitrogen drying efficiency and reducing the nitrogen consumption in the nitrogen drying process.

[0018] In addition, the drying device as a whole has multiple drying components, which can simultaneously process multiple samples at different stages of solid phase extraction. It can be used in steps such as activation, loading, washing and elution in the solid phase extraction process, and has wide applicability and high practicality. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a working principle diagram of an energy-saving solid phase extraction column drying device according to an embodiment of the utility model;

[0020] Figure 2 yes Figure 1 A schematic diagram of the connection structure between a buckle assembly and an air inlet plug of an energy-saving solid phase extraction column drying device in an embodiment of the utility model;

[0021] Figure 3 yes Figure 2 Cross-sectional view of the middle snap assembly.

[0022] In the figure: 1-gas splitter, 2-splitter outlet, 3-nitrogen source, 4-pressure reducing valve, 5-C-type quick connector, 6-pressure gauge, 7-air guide tube, 8-semi-ring assembly, 81-semi-ring buckle, 811-upper splint, 812-lower splint, 9-locking screw, 10-inlet plug, 101-connecting piece, 102-conical plug body, 11-gas pressure regulating valve, 12-solid phase extraction column, 121-connecting skirt. DETAILED DESCRIPTION

[0023] In order to make the purpose, technical solution and advantages of the utility model clearer, the implementation mode of the utility model will be further described below in conjunction with the accompanying drawings.

[0024] Please refer to Figures 1 to 3 , an energy-saving solid phase extraction column drying device, comprising a nitrogen source 3, a gas splitter 1 and a plurality of drying components. In this embodiment, the nitrogen source 3 is a nitrogen bottle filled with high-pressure nitrogen.

[0025] The nitrogen source 3 is connected to the gas diverter 1, and a plurality of diverter gas outlets 2 are provided on the gas diverter 1. The drying component includes a blowing pipe and a solid phase extraction column 12; each drying component is connected to a diverter gas outlet 2, so that the nitrogen source 3 can blow gas to a plurality of solid phase extraction columns 12 at the same time.

[0026] The upper end of the solid phase extraction column 12 is an air inlet end, and an air inlet plug 10 is provided at the air inlet end of the solid phase extraction column 12. The air inlet plug 10 is fixed to the air inlet end of the solid phase extraction column 12 by a snap assembly. The air inlet plug 10 is used to seal the upper end of the solid phase extraction column 12 as the air inlet end. The air inlet plug 10 is axially provided with an air guide pipe 7, one end of the air guide pipe 7 is located in the solid phase extraction column 12, and the other end passes through the air inlet plug 10 and extends to the outside of the solid phase extraction column 12; one end of the air blowing pipe is connected to the diverter air outlet 2, and the other end is connected to the air guide pipe 7. The air blowing pipe is provided with an air pressure regulating valve 11 and a barometer 6.

[0027] After the nitrogen bottle is opened, the nitrogen in it enters the solid phase extraction column 12 through the gas splitter, the blowing pipe, and the air guide pipe 7, thereby drying the solvent in the solid phase extraction column 12. The air inlet plug 10 seals the gap between the air guide pipe 7 and the upper side wall of the solid phase extraction column 12 to prevent the gas from escaping from the upper end of the solid phase extraction column 12. The pressure regulating valve 11 and the pressure gauge 6 can accurately adjust the air intake of the air guide pipe 7 to meet the nitrogen flow requirements during the nitrogen blowing process of the solid phase extraction column 12. The nitrogen blowing efficiency of the solid phase extraction column 12 is improved and the nitrogen blowing time of the solid phase extraction column 12 is shortened.

[0028] Preferably, the nitrogen source and the gas diverter are connected via an air delivery pipe, and the air delivery pipe is provided with a pressure reducing valve 4. The pressure reducing valve 4 is used to adjust the outlet pressure of the nitrogen source 3 to maintain a stable gas supply of the nitrogen source 3. Both ends of the air blowing pipe are provided with C-type quick connectors, and the air blowing pipe is connected to the diverter outlet 2 and the air guide pipe 7 through the C-type quick connector. The C-type quick connector allows the air blowing pipe to be conveniently connected to the diverter outlet 2 and the air guide pipe 7.

[0029] Preferably, the air inlet plug includes a connecting piece 101 and a truncated cone plug body connected to a surface of the connecting piece 101, wherein the thicker end of the truncated cone plug body is connected to the connecting piece 101, and the thinner end of the truncated cone plug body extends into the solid phase extraction column 12, and the connecting piece 101 is fixed to the air inlet end of the solid phase extraction column 12 through a buckle assembly. The air inlet plug and the air guide pipe 7 are both made of transparent PP plastic material, and the two are integrally formed.

[0030] Preferably, a connecting skirt 121 is provided at the edge of the air inlet end of the solid phase extraction column 12, the edge of the connecting piece 101 is attached to the connecting skirt 121, and the buckle assembly clamps the connecting piece 101 and the connecting skirt 121. The buckle assembly includes two semi-ring buckles 811, and the two semi-ring buckles 81 are buckled together to form a circular ring structure. Each semi-ring buckle 811 includes an upper clamping plate 811 and a lower clamping plate 812 connected together at the outer edges. The upper clamping plate 811 and the lower clamping plate 812 are respectively located on the upper side of the connecting piece 101 and the lower side of the connecting skirt 121. A threaded boss is provided on the lower surface of the lower clamping plate 812, and a locking threaded hole penetrating the lower clamping plate 812 is provided in the threaded boss. A locking screw 9 is provided in the locking threaded hole, and the end of the locking screw 9 presses the connecting skirt 121 upward. In this embodiment, the two semi-ring buckles 81 are made of stainless steel.

[0031] Furthermore, a threaded boss is provided on the lower surface of the lower clamping plate 812, a locking threaded hole penetrating the lower clamping plate 812 is provided in the threaded boss, a locking screw 9 is provided in the locking threaded hole, and the end of the locking screw 9 presses the connecting skirt 121 upward.

[0032] In this document, the directional words such as front, back, top, and bottom are defined by the positions of the components in the drawings and the positions of the components relative to each other, and are only for the sake of clarity and convenience in expressing the technical solution. It should be understood that the use of the directional words should not limit the scope of protection claimed in this application.

[0033] In the absence of conflict, the above embodiments and features in the embodiments may be combined with each other.

[0034] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. An energy-saving solid phase extraction column drying device, characterized in that: It includes a nitrogen source, a gas splitter, and a plurality of drying components; The nitrogen source is connected to the gas splitter, a plurality of splitter gas outlets are provided on the gas splitter, and the drying assembly includes a blow pipe and a solid phase extraction column; The air inlet end of the solid phase extraction column is provided with an air inlet plug, which is fixed to the air inlet end of the solid phase extraction column by a buckle assembly, and the air inlet plug is axially provided with an air guide tube, one end of which is located in the solid phase extraction column, and the other end of which passes through the air inlet plug and extends to the outside of the solid phase extraction column; One end of the air blowing pipe is connected to the air outlet of the diverter, and the other end is connected to the air guide pipe. An air pressure regulating valve is arranged on the air blowing pipe.

2. The energy-saving solid phase extraction column drying device according to claim 1, characterized in that: The nitrogen source and the gas diverter are connected via a gas pipeline, and a pressure reducing valve is provided on the gas pipeline.

3. The energy-saving solid phase extraction column drying device according to claim 1, characterized in that: Each of the air blowing pipes is also provided with an air pressure gauge.

4. The energy-saving solid phase extraction column drying device according to claim 1, characterized in that: Both ends of the air blowing pipe are provided with C-type quick connectors, and the air blowing pipe is connected to the air outlet of the diverter and the air guide pipe through the C-type quick connectors.

5. The energy-saving solid phase extraction column drying device according to claim 1, characterized in that: The air inlet plug includes a connecting plate and a conical plug body connected to a surface of the connecting plate, wherein the thicker end of the conical plug body is connected to the connecting plate, and the thinner end of the conical plug body extends into the solid phase extraction column, and the connecting plate is fixed to the air inlet end of the solid phase extraction column by a snap assembly.

6. The energy-saving solid phase extraction column drying device according to claim 1, characterized in that: The air inlet plug and the air guide pipe are both made of transparent PP plastic material and are integrally formed.

7. The energy-saving solid phase extraction column drying device according to claim 5, characterized in that: The edge of the air inlet end of the solid phase extraction column is provided with a connecting skirt, the edge of the connecting piece is attached to the connecting skirt, and the buckle assembly clamps the connecting piece and the connecting skirt.

8. The energy-saving solid phase extraction column drying device according to claim 7, characterized in that: The buckle assembly includes two half-ring buckles, which are closed to form a circular ring structure. Each half-ring buckle includes an upper clamping plate and a lower clamping plate whose outer edges are connected together. The upper clamping plate and the lower clamping plate are respectively located on the upper side of the connecting plate and the lower side of the connecting skirt, thereby clamping the connecting plate and the connecting skirt.

9. The energy-saving solid phase extraction column drying device according to claim 8, characterized in that: The two half-ring buckles are both made of stainless steel.

10. The energy-saving solid phase extraction column drying device according to claim 8, characterized in that: A threaded boss is provided on the lower surface of the lower clamping plate, a locking threaded hole penetrating the lower clamping plate is provided in the threaded boss, a locking screw is provided in the locking threaded hole, and the end of the locking screw presses the connecting skirt upwards.

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