Sheath flow impedance detection device

Abstract

The utility model provides a sheath flow impedance detection device. The sheath flow impedance detection device comprises a front pool shell, a rear pool shell, a counting assembly, a sample needle group and a capture tube, a first notch and a second notch are respectively formed in two opposite ends of the forebay shell; a forebay cavity communicated with the first notch and the second notch is formed in the forebay shell; a rear pond cavity is formed in the rear pond shell; the rear pond shell is inserted into the second notch; the counting assembly is arranged at the communication part of the front tank cavity and the rear tank cavity; the sample needle group is inserted into the front tank cavity from the first notch and faces the counting assembly; the capturing pipe is inserted into the rear pond cavity from the second notch; the sample needle group and the first notch are matched to realize fastening connection; and the capturing pipe is matched with the second notch to realize fastening connection. According to the sheath flow impedance detection device provided by the invention, the sample needle group is in fastening connection with the forebay shell through the first notch, and the capture tube is in fastening connection with the forebay shell through the second notch, so that the risk that the sample needle group and the capture tube group are not coaxial is avoided.

Description

Technical Field

[0001] The present application relates to the technical field of medical equipment, and in particular to a sheath flow impedance detection device. Background Art

[0002] The sheath flow impedance counting detection device is a commonly used counting device in a blood analyzer, which is mainly composed of a front cell housing, a sample needle, a rear cell housing, a capture tube, a plurality of connectors connected to the front cell housing and the rear cell housing, and a counting assembly (including a gem hole). In order to ensure the accuracy of the counting, the sheath flow impedance counting detection device with this structure requires that the sample needle and the capture tube remain coaxial during measurement.

[0003] In the related art, the sample needle is tightly assembled with the front cell shell, the capture tube is tightly assembled with the rear cell shell, and the front cell shell and the rear cell shell are fixedly assembled or detachably assembled. This leads to the risk of misalignment between the sample needle and the capture tube due to the cumulative tolerance of the assembly, thus affecting the accuracy of the counting. Utility Model Content

[0004] The technical problem to be solved by the present application is to provide a sheath flow impedance detection device to solve the defect of the risk of misalignment between the sample needle and the capture tube in the existing sheath flow impedance detection device.

[0005] An embodiment of the present application provides a sheath flow impedance detection device, which includes a front pool shell, a rear pool shell, a counting component, a sample needle group and a capture tube; the front pool shell is provided with a first slot and a second slot at opposite ends thereof; the front pool shell is provided with a front pool cavity which is respectively connected with the first slot and the second slot; the rear pool shell is provided with a rear pool cavity; the rear pool shell is inserted into the second slot so that the rear pool cavity is connected with the front pool cavity; the counting component is provided at the connection between the front pool cavity and the rear pool cavity; the sample needle group is inserted into the front pool cavity from the first slot and faces the counting component; the capture tube is inserted into the rear pool cavity from the second slot and faces the counting component; wherein the sample needle group and the first slot cooperate to achieve a fastened connection; the capture tube and the second slot cooperate to achieve a fastened connection.

[0006] The sheath flow impedance detection device provided in the embodiment of the present application can avoid the risk of misalignment between the sample needle group and the capture tube group due to the assembly tolerance between the front cell shell and the rear cell shell by respectively setting a first notch and a second notch at the opposite ends of the front cell shell, and making the sample needle group fastened to the front cell shell through the first notch, and making the capture tube fastened to the front cell shell through the second notch, thereby improving the detection counting efficiency and accuracy of the sheath flow impedance detection device. BRIEF DESCRIPTION OF THE DRAWINGS

[0007] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0008] Figure 1 is a schematic diagram of the structure of a sheath flow impedance detection device in some embodiments of the present application;

[0009] Figure 2 yes Figure 1 A schematic diagram of the structural disassembly of the sheath flow impedance detection device in the embodiment;

[0010] Figure 3 yes Figure 1 A schematic diagram of the cross-sectional structure of the sheath flow impedance detection device along the AA direction in the embodiment;

[0011] Figure 4 is a schematic diagram of the cross-sectional structure of a sample needle assembly in some embodiments of the present application;

[0012] Figure 5 is a schematic diagram of the cross-sectional structure of a capture tube in some embodiments of the present application;

[0013] Figure 6 It is a schematic diagram of the structural disassembly of the fore cell housing and the sample needle assembly in some embodiments of the present application;

[0014] Figure 7 It is a schematic diagram of the partial structural disassembly of the sheath flow impedance detection device in some embodiments of the present application. DETAILED DESCRIPTION

[0015] The present application is further described in detail below in conjunction with the accompanying drawings and examples. It is particularly noted that the following examples are only used to illustrate the present application, but are not intended to limit the scope of the present application. Similarly, the following examples are only some embodiments of the present application rather than all embodiments, and all other embodiments obtained by ordinary technicians in the field without making creative work are within the scope of protection of the present application.

[0016] Reference to "embodiments" herein means that a particular feature, structure, or characteristic described in conjunction with the embodiments may be included in at least one embodiment of the present application. The appearance of the phrase in various locations in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described herein may be combined with other embodiments.

[0017] See also Figures 1 to 3 , Figure 1 is a schematic diagram of the structure of a sheath flow impedance detection device 100 in some embodiments of the present application, Figure 2 yes Figure 1 A schematic diagram of the structural disassembly of the sheath flow impedance detection device 100 in the embodiment, Figure 3 yes Figure 1 Schematic diagram of the cross-sectional structure of the sheath flow impedance detection device 100 along the AA direction in the embodiment.

[0018] The sheath flow impedance detection device 100 may include a front pool housing 10, a rear pool housing 20, a counting assembly 30, a sample needle group 40 and a capture tube 50. The front pool housing 10 has two opposite ends, namely a first end 101 and a second end 102, and a front pool chamber 103 disposed between the first end 101 and the second end 102 and disposed inside the front pool housing 10. The rear pool chamber 201 is disposed in the rear pool housing 20. When the front pool housing 10 and the rear pool housing 20 are docked and assembled, the front pool chamber 103 is connected to the rear pool chamber 201. The counting assembly 30 is disposed at the connection between the front pool chamber 103 of the front pool housing 10 and the rear pool chamber 201 of the rear pool housing 20.

[0019] Further, the sample needle group 40 is arranged on the first end 101 of the front pool housing 10 and faces the counting assembly 30. The capture tube 50 is arranged on the second end 102 of the front pool housing 10 and faces the counting assembly 30. The rear pool housing 20 is assembled on the second end 102 of the front pool housing 10, and the capture tube 50 is inserted into the rear pool cavity 201 of the rear pool housing 20 from the side of the rear pool housing 20 away from the front pool housing 10, and cooperates with the front pool housing 10 to achieve a fastening connection. The sample needle group 40 is inserted into the front pool cavity 103 of the front pool housing 10 from the side of the front pool housing 10 away from the rear pool housing 20, and cooperates with the front pool housing 10 to achieve a fastening connection.

[0020] In one embodiment, the first end 101 and the second end 102 of the front pool housing 10 are respectively provided with a first notch 110 and a second notch 120, and the first notch 110 and the second notch 120 are respectively connected to the front pool chamber 103, that is, the front pool housing 10 is provided with a front pool chamber 103 connected to the first notch 110 and the second notch 120. The rear pool housing 20 is inserted in the second notch 120 so that the rear pool chamber 201 is connected to the front pool chamber 103. The sample needle group 40 is inserted in the front pool chamber 103 from the first notch 110 and faces the counting assembly 30. The capture tube 50 is inserted in the rear pool chamber 201 from the second notch 120 and faces the counting assembly 30. Among them, the sample needle group 40 and the first notch 110 cooperate to achieve a fastening connection, so that the sample needle group 40 and the front pool housing 10 are fastened. The capture tube 50 and the second notch 120 cooperate to achieve a fastening connection, so that the capture tube 50 and the front pool shell 10 are fastened together. In the actual assembly process, the capture tube 50 can first be docked with the rear pool shell 20 to form an integral structure, and then the integral structure is inserted into the second notch 120, so that the rear pool cavity 201 of the rear pool shell 20 communicates with the front pool cavity 103 of the front pool shell 10, and the capture tube 50 cooperates with the second notch 230 to achieve a fastening connection.

[0021] Of course, in other embodiments, the sample needle assembly 40 and the capture tube 50 may also be fastened to the fore cell housing 10 by connection methods such as threading, bonding or welding.

[0022] It can be understood that the sample needle group 40 and the capture tube 50 are respectively fastened to the front cell housing 10, which can eliminate or reduce the influence of the assembly tolerance between the front cell housing 10 and the rear cell housing 20 on the coaxiality of the sample needle group 40 and the capture tube 50. That is, through the above-mentioned structural setting, the risk of the sample needle group 40 and the capture tube 50 not being coaxial due to the assembly tolerance between the front cell housing 10 and the rear cell housing 20 can be avoided, thereby ensuring the detection accuracy of the sheath flow impedance detection device.

[0023] In one embodiment, one of the sample needle group 40 and the first notch 110 is provided with a first screw-in ear 401, and the other is provided with a first screw-in seat 402, and the first screw-in ear 401 and the first screw-in seat 402 cooperate to achieve a fastening connection, so that the sample needle group 40 is fastened to the fore cell housing 10. One of the capture tube 50 and the second notch 120 is provided with a second screw-in ear 501, and the other is provided with a second screw-in seat 502, and the second screw-in ear 501 and the second screw-in seat 502 cooperate to achieve a fastening connection, so that the capture tube 50 is fastened to the fore cell housing 10. Of course, in other embodiments, the sample needle group 40 and the first notch 110 can also be fastened by screwing, welding or bonding; the capture tube 50 and the second notch 120 can also be fastened by screwing, welding or bonding.

[0024] like Figures 1 to 3 As shown, the sample needle assembly 40 is provided with a first screw-in ear 401, and the first notch 110 is provided with a first screw-in seat 402. The first screw-in ear 401 and the first screw-in seat 402 cooperate to achieve a fastening connection, so that the sample needle assembly 40 is fastened to the fore cell housing 10. The capture tube 50 is provided with a second screw-in ear 501, and the second notch 120 is provided with a second screw-in seat 502. The second screw-in ear 501 and the second screw-in seat 502 cooperate to achieve a fastening connection, so that the capture tube 50 is fastened to the fore cell housing 10.

[0025] Of course, in other embodiments, the first screw-in ear 401 can be arranged on the first slot 110, and the first screw-in seat 402 can be arranged on the sample needle group 40; the second screw-in ear 501 can be arranged on the second slot 120, and the second screw-in seat 502 can be arranged on the capture tube 50. Those skilled in the art can directly obtain it by adaptively adjusting the technical solution provided in the embodiment of the present application, so it will not be elaborated here.

[0026] In addition, in some embodiments, the difference from the above structure is that only the first screw buckle ear 401 is installed on the sample needle group 40, and the first screw buckle seat 402 is set on the first notch 110. The sample needle group 40 is detachably connected and fixed to the forecell housing 10 through the clamping connection between the first screw buckle ear 401 and the first screw buckle seat 402. The capture tube 50 and the forecell housing 10 can be connected by common adhesive connection or screw connection, which can also be implemented.

[0027] In some other embodiments, only the second screw buckle ear 501 is installed on the capture tube 50, and the second screw buckle seat 502 is provided on the second notch 120. The capture tube 50 is connected to the forecell housing 10 by the second screw buckle ear 501 and the second screw buckle seat 502, so as to be detachably connected and fixed. The sample needle assembly 40 and the forecell housing 10 can be connected by common adhesive or screw connection, which does not affect the implementation.

[0028] As a variation of the above embodiment, the first turn buckle ear 401 and the first turn buckle seat 402 can also be installed by a clamping connection method instead of the above-mentioned turn buckle connection method. For example, during the installation process, the first turn buckle seat 402 can be deformed to a certain extent (recoverable) by external force, so that there is a large enough space between them to place the first turn buckle ear 401 in its groove. After the placement is completed, the external force is removed, the first turn buckle seat 402 is reset, and its groove clamps the first turn buckle ear 401 therein to complete the installation, and the disassembly process is reversed. The above structure does not change the essence of the clamping connection between the two in the present application.

[0029] As a variation of the above embodiment, the second turn buckle ear 501 and the second turn buckle seat 502 can also be installed by a clamping connection method instead of the above-mentioned turn buckle connection method. For example, during the installation process, the second turn buckle seat 502 can be deformed to a certain extent (recoverable) by external force, so that there is a large enough space between them to place the second turn buckle ear 501 in its groove. After the placement is completed, the external force is removed, the second turn buckle seat 502 is reset, and its groove clamps the second turn buckle ear 501 therein to complete the installation, and the disassembly process is reversed. The above structure does not change the essence of the clamping connection between the two in the present application.

[0030] It is understandable that the present application is not limited to the above-mentioned embodiments, and a screw-in seat may be provided on the sample needle group and / or the capture tube, and a screw-in ear may be provided on the front pool housing, and the detachable and fixed connection mode between the screw-in ear and the screw-in seat has not changed; at the same time, the number of the installed screw-in ears and the screw-in seat is not limited to two in the above-mentioned embodiments, and it can be adjusted according to the size of the equipment and the sealing strength, such as more than two. As long as the screw-in ears and the screw-in seats are matched and fixedly connected. Of course, the fixing structure of the screw-in ears and the screw-in seat of the present application can also be applied to other sheath flow impedance detection devices of the same or similar structures, as long as the sample needle group is detachably fixed on the front pool housing to seal the front pool inner cavity, and the capture tube is detachably fixed on the front pool housing to seal the rear pool inner cavity, the purpose of convenient disassembly can be achieved.

[0031] Furthermore, the sample needle assembly 40 is detachably fixed to the front cell housing 10 and seals the front cell cavity 103 , and the capture tube 50 is detachably fixed to the front cell housing 10 and seals the rear cell cavity 201 .

[0032] The front pool housing 10 and the rear pool housing 20 can be connected and fixed as one. The connection method of the front pool housing 10 and the rear pool housing 20 can adopt common connection methods such as bonding or screws.

[0033] In one embodiment, a receiving groove 104 is provided on one side of the front pool cavity 103 of the front pool housing 10 close to the second end 102 of the front pool housing 10, and an outer convex annular wall 202 is provided on one side of the rear pool cavity 201 of the rear pool housing 20 close to the first end 101 of the front pool housing 10, and the receiving groove 104 and the outer convex annular wall 202 are respectively connected with the front pool cavity 103 and the rear pool cavity 201, and the outer diameter of the outer convex annular wall 202 is equivalent to the inner diameter of the receiving groove 104, and can be placed in the receiving groove 104 to achieve docking. Optionally, the end faces of the front pool housing 10 and the rear pool housing 20 that are connected to each other can be assembled and connected by screwing, bonding or welding.

[0034] It is understandable that the purpose of providing the receiving groove 104 and the outer convex annular wall 202 in the front pool housing 10 and the rear pool housing 20 is, on the one hand, to play a positioning role in the process of connecting the front pool housing 10 and the rear pool housing 20, so as to achieve rapid installation; it can also play a positioning role in the front pool cavity 103 and the rear pool cavity 201, so that the central axes of the two are in the same straight line, ensuring the accuracy of the instrument measurement. On the other hand, the outer convex annular wall 202 extending into the receiving groove 104 can also press the counting component 30 located therein, playing a fixing role.

[0035] Of course, in other embodiments, the front pool housing 10 and the rear pool housing 20 can also be assembled and connected by other structures. Figures 1 to 3 As shown, the sheath flow impedance detection device 100 may further include a fixing member 60, which is used to position and assemble the front pool housing 10 and the rear pool housing 20. For example, the front pool housing 10 may have a first convex portion 105 located outside the front pool cavity 103, and the rear pool housing 20 may have a second convex portion 203 located outside the rear pool cavity 201. The first convex portion 105 and the second convex portion 203 may be provided with fixing holes or screw holes, and the fastening and assembly connection is achieved by screws with the fixing member 60. Among them, the first convex portion 105 may be in a plate-like or block-like shape, the second convex portion 203 may be in a plate-like or block-like shape, and the fixing member 60 may be a fixing plate or a fixing sheet, etc. Optionally, when the front pool shell 10 and the rear pool shell 20 are butt-connected, the first protrusion 105 and the second protrusion 203 are in contact and fit, and the fixing member 60 can be arranged on the side of the first protrusion 105 facing away from the second protrusion 203, or on the side of the second protrusion 203 facing away from the first protrusion 105; the screws or bolts pass through the fixing holes or screw holes on the first protrusion 105 and the second protrusion 203 in turn and are connected to the fixing member 60 so that the first protrusion 105 and the second protrusion 203 are fastened to the fixing member 60.

[0036] In addition, in some embodiments, the fixing member 60 may also be located between the first convex portion 105 and the second convex portion 203, that is, when the front pool housing 10 and the rear pool housing 20 are butt-connected, the first convex portion 105 and the second convex portion 203 cooperate to clamp the fixing member 60. The first convex portion 105 may be fixedly connected to the fixing member 60 by screwing, bonding, welding or clamping, and the second convex portion 203 may be fixedly connected to the fixing member 60 by screwing, bonding, welding or clamping. Of course, the connection may also be achieved by sequentially passing the same screw or bolt through the first convex portion 105, the fixing member 60 and the second convex portion 203.

[0037] Further, the front pool cavity 103 of the front pool housing 10 and the rear pool cavity 201 of the rear pool housing 20 can be a cylindrical chamber structure (circular in cross section), and the two inner cavities are relatively narrowed at their respective bottoms and sealed and docked. Wherein, the bottom of each of the two inner cavities can be understood as the end where the front pool cavity 103 and the rear pool cavity 201 are close to each other and connected. After the front pool housing 10 and the rear pool housing 20 are fixed according to the installation method of the aforementioned front pool housing 10 and the rear pool housing 20, the counting component 30 can be just set at the docking point (between the accommodating groove 104 and the outer convex annular wall 202) of the front pool cavity 103 and the rear pool cavity 201, and connected through the middle small hole of the gem hole in the counting component 30.

[0038] In one embodiment, the bottom of the first notch 110 (e.g., the first bottom wall 113 described below) is provided with a first annular groove 1001 communicating with the front pool chamber 103, and a first sealing ring 701 is provided in the first annular groove 1001, so that when the sample needle assembly 40 is inserted into the front pool chamber 103, the first sealing ring 701 is squeezed to seal the front pool chamber 103. A second annular groove 1002 communicating with the rear pool chamber 201 is provided on the end of the rear pool housing 20 away from the first notch 110, and a second sealing ring 702 is provided in the second annular groove 1002, so that when the capture tube 50 is inserted into the rear pool chamber 201, the second sealing ring 702 is squeezed to seal the rear pool chamber 201.

[0039] Optionally, the first sealing ring 701 and the second sealing ring 702 may be annular gasket structures with an O-shaped or square cross-section. Optionally, the first sealing ring 701 and the second sealing ring 702 may be made of silicone, sealing foam, or other materials that can achieve a sealing effect.

[0040] See also Figure 4 , Figure 4 1 is a schematic diagram of the cross-sectional structure of the sample needle group 40 in some embodiments of the present application, wherein the sample needle group 40 is a structural component connected to the first notch 110 of the fore cell housing 10. The sample needle group 40 may be an axisymmetric structure.

[0041] The sample needle group 40 includes a sample needle 410, a fixing seat 420 and a three-way pipe joint 430. The fixing seat 420 includes an integrally formed first terminal 421 and a first end cap 422, and a through hole 423 that is arranged through the middle of the first terminal 421 and the first end cap 422; the sample needle 410 is bonded and fixed in the through hole 423, and a three-way pipe joint 430 connected to the tail of the sample needle 410 is connected and arranged. The sample needle 410 is in the shape of an elongated needle tube, and a liquid circulation channel is arranged inside it, one end of which is a liquid outlet end (the left side as shown in the figure) for ejecting liquid, and the other end opposite to it is connected to the three-way pipe joint 430, and the two components are liquid-connected. Among them, the first terminal 421 and the first end cap 422 are integrally formed, and the shapes of the two are roughly stepped truncated cones. The main functions of the two structures are to fix the sample needle 410 and to close the front pool chamber 103. When the fixed seat 420 is placed in the front pool cavity 103, since the outer diameter of the first terminal 421 is set to be the same as the inner diameter of the front pool cavity 103, the outer wall of the first terminal 421 is pressed (or in contact) on the inner wall of the front pool cavity 103, and the first end cover 422 extending on the first terminal 421 can seal the open end of the front pool cavity 103. When the fixed seat 420 is completely fixed on the open end of the front pool cavity 103, the front pool cavity 103 is closed to form an annular hollow space. The first sealing ring 701 in the first annular groove 1001 is compressed to a certain extent by the first end cover 422 of the fixed seat 420, so that the fixed seat 420 can seal the front pool inner cavity 31.

[0042] It can be understood that the axially symmetrical structure of the sample needle group 40 in the present application means that the central axes of the sample needle 410 and the fixed seat 420 are on the same straight line, and when the sample needle group 40 is fixed in the front pool cavity 103, the sample needle group 40 can rotate along the common central axis of the sample needle 410 and the fixed seat 420 during the installation process, but will not change the position of the sample needle 410 and the fixed seat 420 relative to the front pool cavity 103, that is, after fixation, the central axes of the front pool cavity 103, the sample needle 410 and the fixed seat 420 are on the same straight line.

[0043] See also Figure 5 , Figure 5 1 is a schematic diagram of a cross-sectional structure of a capture tube 50 in some embodiments of the present application, wherein the capture tube 50 is a structural member connected to the second notch 120 of the forebay housing 10. The capture tube 50 may be an axisymmetric structure.

[0044] The capture tube 50 may include a seat body 510 and a back pool electrode 520 disposed on the seat body 510. The seat body 510 is a tubular structure, and the hollow portion therein is a sample flow capture channel 530, which is used to capture the sample flow ejected from the sample needle group 40. The back pool electrode 520 is fixed by the seat body 510. Among them, the structure of the seat body 510 is similar to the structure of the fixing seat 420 of the above-mentioned sample needle group 40, and is mainly composed of a second terminal 511 and a second end cap 512, and the two are integrally formed. When the seat body 510 is placed in the back pool cavity 201, the outer wall of the second terminal 511 is squeezed (or contacted) on the inner wall of the back pool cavity 201, and the second end cap 512 can seal the open end of the back pool cavity 201. When the seat body 510 is completely fixed on the open end of the back pool cavity 201, the back pool cavity 201 is closed to form an annular hollow space. The second sealing ring 702 in the second annular groove 1002 is compressed to a certain extent by the second end cover 512 of the seat body 510, so that the seat body 510 seals the rear pool cavity 201. The axisymmetric structure of the capture tube 50 means that after the capture tube 50 is fixed to the rear pool shell 20, the central axes of the rear pool cavity 201, the capture tube 50 and the seat body 510 are on the same straight line, and the capture tube 50 can rotate during the installation process without changing the relative positions of the capture tube 50 and the seat body 510 relative to the rear pool cavity 201.

[0045] See again Figures 1 to 3 The sample needle assembly 40 is provided with a first screw-in ear 401, and the first notch 110 is provided with a first screw-in seat 402. The first screw-in ear 401 and the first screw-in seat 402 cooperate to achieve a fastening connection, so that the sample needle assembly 40 is fastened to the fore cell housing 10. The capture tube 50 is provided with a second screw-in ear 501, and the second notch 120 is provided with a second screw-in seat 502. The second screw-in ear 501 and the second screw-in seat 502 cooperate to achieve a fastening connection, so that the capture tube 50 is fastened to the fore cell housing 10.

[0046] Combined with reference Figure 6 , Figure 6 1 is a schematic diagram of the assembly structure of the forepool housing 10 and the sample needle group 40 in some embodiments of the present application. The first end 101 of the forepool housing 10 is provided with a first notch 110 connected to the forepool cavity 103, and the sample needle group 40 is inserted into the forepool cavity 103 from the first notch 110 and seals the forepool cavity 103. Specifically, the first notch 110 may include a first groove wall 111 and a second groove wall 112 that are arranged opposite to each other, and a first bottom wall 113 connected between the first groove wall 111 and the second groove wall 112, and the forepool cavity 103 is connected to the first bottom wall 113. The first annular groove 1001 is provided on the first bottom wall 113 and communicates with the forepool cavity 103. The first screw seat 402 is provided on the first groove wall 111 and / or the second groove wall 112, and the first screw ear 401 is provided on the first end cover 422 of the sample needle group 40.

[0047] Wherein, the first turn buckle ear 401 can rotate relative to the first turn buckle seat 402 so that the sample needle group 40 and the front pool housing 10 are fastened and assembled, or the sample needle group 40 and the front pool housing 10 are disassembled and separated, that is, the sample needle group 40 and the front pool housing 10 can be detachably assembled and connected by the first turn buckle ear 401 and the first turn buckle seat 402. Specifically, the first turn buckle ear 401 is extended and arranged on the side body of the first end cap 422 of the sample needle group 40, and it is two symmetrical flange structures with relative positions. Since the first turn buckle ear 401 is connected as one with the first end cap 422, the purpose of fastening the first end cap 422 can be achieved by fixing the first turn buckle ear 401. In the present embodiment, the end face of the first turn buckle ear 401 away from the first end cap 422 is a cambered surface, and its function is to reduce the area occupied by the first turn buckle ear 401 during the rotation process, and reduce the gap into which the first turn buckle ear 401 is screwed on the first turn buckle seat 402. Optionally, the opposite ends of the end surface of the first screw-in ear 401 facing away from the first end cover 422 are set as wedge surfaces or transition chamfers. The wedge surface can be a plane or an arc surface, etc., and its function is to facilitate the first screw-in ear 401 to be smoothly guided into the first screw-in seat 402 or rotated away from the first screw-in seat 402 during the assembly and disassembly process.

[0048] like Figure 6 As shown, the first groove wall 111 and the second groove wall 112 are both provided with a first turn-button seat 402, and the first turn-button seat 402 on the first groove wall 111 and the first turn-button seat 402 on the second groove wall 112 are staggered, which can avoid interference when the first turn-button ear 401 is screwed into or rotated out of the first turn-button seat 402. Wherein, the staggered arrangement of the first turn-button seat 402 on the first groove wall 111 and the first turn-button seat 402 on the second groove wall 112 refers to the misalignment of the two in the rotation direction of the first turn-button ear 401, rather than the misalignment of the two in the direction in which the sample needle group 40 is inserted into the front pool cavity 103. Further, the first turn-button seat 402 can be a hollow slotted structure arranged on the first groove wall 111 and / or the second groove wall 112, in a strip shape or a block shape. The opening direction of the groove body of the first turn-button seat 402 is perpendicular to the opening direction of the first notch 110.

[0049] in, Figure 6The three directions X, Y, and Z of the sheath flow impedance detection device 100 are defined. Among them, the rotation plane of the first buckle ear 401 can be parallel to the XY plane, and the Z direction is perpendicular to the XY plane. In other words, the Z direction can be understood as the direction in which the sample needle group 40 moves into the front pool cavity 103, and the opposite direction of the Z direction can be understood as the direction in which the sample needle group 40 moves out of the front pool cavity 103. The direction in which the sample needle group 40 moves in or out of the front pool cavity 103 is perpendicular to the XY plane. Optionally, the X direction can be perpendicular to the Y direction. Of course, in other embodiments, the X direction can intersect with the Y direction.

[0050] When the first groove wall 111 and the second groove wall 112 are arranged relative to each other in the X direction, the first turn-on seat 402 on the first groove wall 111 and the first turn-on seat 402 on the second groove wall 112 are staggered in the Y direction; when the first groove wall 111 and the second groove wall 112 are arranged relative to each other in the Y direction, the first turn-on seat 402 on the first groove wall 111 and the first turn-on seat 402 on the second groove wall 112 are staggered in the X direction.

[0051] The first turn-on buckle ear 401 and the first turn-on buckle seat 402 are matched and fixedly connected, which means that in a specific implementation, the first turn-on buckle ear 401 is screwed into the groove body of the corresponding first turn-on buckle seat 402, and the end face of the first turn-on buckle ear 401 is pressed on the inner wall of the corresponding first turn-on buckle seat 402, and an extrusion surface is formed where the first turn-on buckle ear 401 and the first turn-on buckle seat 402 are fixedly connected. It should be pointed out that in addition to the fixing between the first turn-on buckle ear 401 and the first turn-on buckle seat 402, the first sealing ring 701 fastened at the connection between the first end 421 and the first end cover 422 also plays an extrusion role. After the first sealing ring 701 is fastened by the first end cover 422 and compressed and deformed, the first sealing ring 701 will generate a rebound force in the opposite direction of the force acting on the first end cover 422, and the end face of the first turn-on buckle ear 401 arranged on the fixed seat 420 is further pressed against the first turn-on buckle seat 402, thereby increasing the force between the two and preventing loosening.

[0052] In addition, in some embodiments, the first screw-in seat 402 can be provided only on the first groove wall 111 or the second groove wall 112, and at this time, the number of the first screw-in ears 401 and the first screw-in seat 402 is consistent to achieve matching and clamping connection. When the first screw-in seat 402 is provided on the first groove wall 111, when the first screw-in ears 401 are screwed into the first screw-in seat 402 and a tight fit is achieved, the second groove wall 112 and the first end cap 422 can be connected by means of interference fit, so that the connection between the sample needle group 40 and the front pool housing 10 is relatively stable. When the first screw-in seat 402 is provided on the second groove wall 112, when the first screw-in ears 401 are screwed into the first screw-in seat 402 and a tight fit is achieved, the first groove wall 111 and the first end cap 422 can be connected by means of interference fit, so that the connection between the sample needle group 40 and the front pool housing 10 is relatively stable.

[0053] Combined with reference Figure 7 , Figure 7 1 is a schematic diagram of the partial assembly structure of the sheath flow impedance detection device 100 in some embodiments of the present application. The second end 102 of the front pool housing 10 is provided with a second notch 120 connected to the front pool cavity 103, and the capture tube 50 is inserted into the rear pool cavity 201 of the rear pool housing 20 from the second notch 120, and the rear pool cavity 201 is sealed. Specifically, the second notch 120 may include a third groove wall 121 and a fourth groove wall 122 that are relatively arranged, and a second bottom wall 123 connected between the third groove wall 121 and the fourth groove wall 122, and the front pool cavity 103 is connected to the second bottom wall 123. As mentioned above, the accommodating groove 104 is arranged on the side of the second bottom wall 123 away from the first end 101 and is located between the third groove wall 121 and the fourth groove wall 122. The outer convex annular wall 202 on the rear pool housing 20 is inserted into the accommodating groove 104 to realize the assembly positioning of the front pool housing 10 and the rear pool housing 20. The second annular groove 1002 is disposed on the side of the rear pool housing 20 away from the second bottom wall 123 and communicates with the rear pool cavity 201. The second screw seat 502 is disposed on the third groove wall 121 and / or the fourth groove wall 122, and the second screw ear 501 is disposed on the second end cover 512 of the capture tube 50.

[0054] Wherein, the second turn buckle ear 501 can rotate relative to the second turn buckle seat 502 so that the capture tube 50 and the forepool housing 10 are fastened and assembled, or the capture tube 50 and the forepool housing 10 are disassembled and separated, that is, the capture tube 50 and the forepool housing 10 can be connected by the second turn buckle ear 501 and the second turn buckle seat 502 to realize detachable assembly. Specifically, the second turn buckle ear 501 is extended on the side body of the second end cap 512 of the capture tube 50, and it is two symmetrical flange structures that are relatively arranged in position. Because the second turn buckle ear 501 is connected as one with the second end cap 512, the purpose of fastening the second end cap 512 can be achieved by fixing the second turn buckle ear 501. In the present embodiment, the end face of the second turn buckle ear 501 away from the second end cap 512 is a cambered surface, and its effect is to reduce the area occupied by the second turn buckle ear 501 in the rotation process, and reduce the gap into which the second turn buckle ear 501 is screwed on the second turn buckle seat 502. Optionally, the opposite ends of the end surface of the second screw-in ear 501 facing away from the second end cover 512 are set as wedge surfaces or transition chamfers. The wedge surface can be a plane or an arc surface, etc., and its function is to facilitate the second screw-in ear 501 to be smoothly guided into the second screw-in seat 502 or rotated away from the second screw-in seat 502 during the assembly and disassembly process.

[0055] like Figure 7 As shown, the third groove wall 121 and the fourth groove wall 122 are both provided with a second turn-on seat 502, and the second turn-on seat 502 on the third groove wall 121 and the second turn-on seat 502 on the fourth groove wall 122 are staggered, which can avoid interference when the second turn-on ear 501 is screwed into or rotated out of the second turn-on seat 502. Wherein, the second turn-on seat 502 on the third groove wall 121 and the second turn-on seat 502 on the fourth groove wall 122 are staggered, which means that the two are staggered in the rotation direction of the second turn-on ear 501, rather than the two are staggered in the direction of the capture tube 50 inserted into the rear pool cavity 201. Further, the second turn-on seat 502 can be a hollow slotted structure arranged on the third groove wall 121 and / or the fourth groove wall 122, in a strip shape or a block shape. The opening direction of the groove body of the second turn-on seat 502 is perpendicular to the opening direction of the second notch 120.

[0056] Among them, the rotation plane of the second buckle ear 501 can be parallel to the XY plane, and the Z direction is perpendicular to the XY plane. In other words, the Z direction can be understood as the direction in which the capture tube 50 moves into the rear pool cavity 201, and the opposite direction of the Z direction can be understood as the direction in which the capture tube 50 moves out of the rear pool cavity 201. The direction in which the capture tube 50 moves in or out of the rear pool cavity 201 is perpendicular to the XY plane. Optionally, the X direction can be perpendicular to the Y direction. Of course, in other embodiments, the X direction can intersect with the Y direction.

[0057] When the third groove wall 121 and the fourth groove wall 122 are arranged relative to each other in the X direction, the second turn-button seat 502 on the third groove wall 121 and the second turn-button seat 502 on the fourth groove wall 122 are staggered in the Y direction; when the third groove wall 121 and the fourth groove wall 122 are arranged relative to each other in the Y direction, the second turn-button seat 502 on the third groove wall 121 and the second turn-button seat 502 on the fourth groove wall 122 are staggered in the X direction.

[0058] The second turn-lock ear 501 and the second turn-lock seat 502 are matched and fixedly connected, which means that in a specific implementation, the second turn-lock ear 501 is screwed into the groove body of the corresponding second turn-lock seat 502, and the end face of the second turn-lock ear 501 is pressed on the inner wall of the corresponding second turn-lock seat 502, and an extrusion surface is formed where the second turn-lock ear 501 and the second turn-lock seat 502 are fixed. It should be pointed out that in addition to the fixing between the second turn-lock ear 501 and the second turn-lock seat 502, the second sealing ring 702 fastened at the connection between the second end 511 and the second end cover 512 also plays an extrusion role. After the second sealing ring 702 is fastened by the second end cover 512 and compressed and deformed, the second sealing ring 702 will generate a rebound force in the opposite direction of the force acting on the second end cover 512, and the end face of the second turn-lock ear 501 arranged on the second end cover 512 is further pressed against the second turn-lock seat 502, thereby increasing the force between the two and preventing loosening.

[0059] In addition, in some embodiments, the second screw-in seat 502 can be arranged only on the third groove wall 121 or the fourth groove wall 122, and at this time, the number of the second screw-in ears 501 and the second screw-in seat 502 is consistent to achieve matching and clamping connection. When the second screw-in seat 502 is arranged on the third groove wall 121, when the second screw-in ears 501 are screwed into the second screw-in seat 502 and a tight fit is achieved, the fourth groove wall 122 and the second end cover 512 can be connected by interference fit or the like, so that the connection between the capture tube 50 and the front pool housing 10 is more stable. When the second screw-in seat 502 is arranged on the fourth groove wall 122, when the second screw-in ears 501 are screwed into the second screw-in seat 502 and a tight fit is achieved, the third groove wall 121 and the second end cover 512 can be connected by interference fit or the like, so that the connection between the capture tube 50 and the front pool housing 10 is more stable.

[0060] During the matching and installation process of the front pool housing 10 and the rear pool housing 20, the sample needle group 40 is inserted into the first notch 110 and cooperates with the front pool housing 10 to achieve a fast connection, and the front pool cavity 103 can be sealed at the same time; the rear pool housing 20 is inserted into the second notch 120 and is fastened with the front pool housing 10, so that the rear pool cavity 201 is connected with the front pool cavity 103. The capture tube 50 is inserted into the second notch 120 and cooperates with the front pool housing 10 to achieve a fast connection, and the rear pool cavity 201 can be sealed. After the front pool cavity 103 and the rear pool cavity 201 are sealed, the sheath flow impedance detection device 100 can be operated. The counting component 30 is located at the connection between the front pool cavity 103 and the rear pool cavity 201, and is fixed by the extrusion between the accommodating groove 104 and the outer convex annular wall 202, respectively, and is a structural member for counting the tiny particles contained in the sample liquid.

[0061] As mentioned above, the receiving groove 104 can be arranged on the side of the second bottom wall of the second notch 120 close to the rear pool housing, and the outer convex annular wall 202 can be arranged on the side of the second bottom wall of the rear pool housing 20 close to the second notch 120. The receiving groove 104 and the outer convex annular wall 202 are respectively connected with the front pool cavity 103 and the rear pool cavity 201. The outer diameter of the outer convex annular wall 202 is equivalent to the inner diameter of the receiving groove 104, and can be placed in the receiving groove 104 to achieve docking. The counting component 30 is arranged between the receiving groove 104 and the outer convex annular wall 202.

[0062] like Figures 1 to 3 As shown, the counting component 30 may include a front pool gasket 310, a gem hole 320 and a gem hole gasket 330 which are stacked in sequence. The gem hole gasket 330 is arranged on a side close to the outer convex ring wall 202. The principle of the counting component 30 for counting tiny particles in the sample liquid is: the sample liquid containing tiny particles passes through the gem hole 320. Since the sample liquid is a good conductor of electricity, and the particles therein are poor conductors of electricity, when the particles pass through the gem hole 320, the resistance on both sides of the gem hole 320 will be significantly greater than the resistance on both sides when no particles pass through the gem hole 320. At this time, the relevant information of the particles can be obtained by detecting the electrical signal generated by the change of resistance between the front pool chamber 103 and the back pool chamber 201.

[0063] The specific process of realizing the detachable connection between the sample needle group 40 and the fore cell housing 10 by the matching and fastening connection between the first screw buckle ear 401 and the first screw buckle seat 402 is as follows: first, the front end of the sample needle group 40 is inserted into the fore cell chamber 103, the outer wall of the first terminal 421 is pressed (or in contact) on the inner wall of the fore cell chamber 103, and the first end cap 422 is fitted on the open end of the fore cell chamber 103. Then, the sample needle group 40 is rotated so that the first screw buckle ear 401 is screwed into the first screw buckle seat 402. In this process, the sample needle group 40 simultaneously compresses the first sealing ring 701 in the first annular groove 1001, so as to realize the sealing effect of the sample needle group 40 on the fore cell chamber 103 and the fastening connection between the sample needle group 40 and the fore cell housing 10.

[0064] The specific process of realizing the detachable connection between the capture tube 50 and the front pool shell 10 by matching and fixing the second screw-in ear 501 and the second screw-in seat 502 in the present application is as follows: first, the rear pool electrode 520 is connected and fixed to the capture tube 50, and then the front end of the capture tube 50 is inserted into the rear pool cavity 201, and the outer wall of the second end cap 511 is squeezed (or contacts) on the inner wall of the rear pool cavity 201, and the second end cover 512 is fitted on the open end of the rear pool cavity 201. Next, the docked capture tube 50 and rear pool shell 20 are synchronously inserted into the second slot 120 of the front pool shell 10, so that the rear pool cavity 201 of the rear pool shell 20 is connected with the front pool cavity 103 of the front pool shell 10, and then the capture tube 50 is rotated so that the second screw buckle ear 501 is screwed into the second screw buckle seat 502. During this process, the capture tube 50 synchronously compresses the second sealing ring 702 in the second annular groove 1002, thereby realizing the sealing effect of the capture tube 50 on the rear pool cavity 201 and the fastening connection between the capture tube 50 and the front pool shell 10.

[0065] After the assembly is completed, the sheath flow impedance detection device 100 can perform counting according to the above counting process. At the same time, based on the sample needle assembly 40 and the capture tube 50 being fastened and assembled with the front cell housing 10, respectively, the risk of misalignment between the sample needle assembly 40 and the capture tube assembly 50 due to the assembly tolerance between the front cell housing 10 and the rear cell housing 20 can be avoided.

[0066] See again Figures 1 to 3 , the sheath flow impedance detection device 100 may also include a plurality of connectors respectively connected to the front pool chamber 103 and the rear pool chamber 201. Optionally, the sheath flow impedance detection device 100 may include a first connector 801 and a second connector 802 provided on the front pool housing 10, and a third connector 803 and a fourth connector 804 provided on the rear pool housing 20, wherein the first connector 801 and the second connector 802 are respectively connected to the front pool chamber 103, and the third connector 803 and the fourth connector 804 are respectively connected to the rear pool chamber 201.

[0067] It should be understood that the meaning of "multiple" is at least two, such as two, three, etc., unless otherwise clearly and specifically limited. It should be noted that the terms "first", "second", and "third" in this application are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, the features defined as "first", "second", and "third" may explicitly or implicitly include at least one of the features. All directional indications in the embodiments of the present application (such as up, down, left, right, front, back...) are only used to explain the relative position relationship, movement, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication also changes accordingly.

[0068] Further, one of the first joint 801 and the second joint 802 can be used as an inlet joint for the cleaning liquid, and the other can be used as an outlet joint for the cleaning liquid, so that the cleaning liquid can enter and exit the front tank chamber 103, thereby achieving a cleaning effect. One of the third joint 803 and the fourth joint 804 can be used as an inlet joint for the cleaning liquid, and the other can be used as an outlet joint for the cleaning liquid, so that the cleaning liquid can enter and exit the rear tank chamber 201, thereby achieving a cleaning effect. Figure 1 and Figure 3 As shown, for the front tank housing 10, the cleaning liquid can enter the front tank cavity 103 from the second joint 802 and flow out of the front tank cavity 103 through the first joint 801, so that the cleaning liquid can effectively clean the front tank cavity 103 and the counting component 30 exposed in the front tank cavity 103. For the rear tank housing 20, the cleaning liquid can enter the rear tank cavity 201 from the fourth joint 804 and flow out of the rear tank cavity 201 through the third joint 803, so that the cleaning liquid can effectively clean the rear tank cavity 201 and the counting component 30 exposed in the rear tank cavity 201.

[0069] Optionally, the central axis of the connection between the first joint 801 and the front pool chamber 103 is substantially perpendicular to the central axis of the front pool chamber 103, and the angle between the central axis of the connection between the second joint 802 and the front pool chamber 103 and the central axis of the front pool chamber 103 is less than 90°, and is inclined toward the counting component 30, so that when the front pool chamber 103 is cleaned, the cleaning fluid entering the second joint 802 can be smoothly flushed into the counting component 30 in the inner cavity, thereby improving the cleaning effect.

[0070] Optionally, the central axis of the connection point between the third joint 803 and the rear pool cavity 201 is substantially perpendicular to the central axis of the rear pool cavity 201, and the angle between the central axis of the connection point between the fourth joint 804 and the rear pool cavity 201 and the central axis of the rear pool cavity 201 is less than 90°, and is inclined toward the counting component 30, so that when the rear pool cavity 201 is cleaned, the cleaning fluid entering the fourth joint 804 can be smoothly flushed into the counting component 30 in the inner cavity, thereby improving the cleaning effect.

[0071] In one embodiment, the first connector 801 can be used as a front cell electrode, that is, the material of the first connector 801 is a conductor. The rear cell electrode 520 is inserted into the rear cell cavity 201. When the sheath flow impedance detection device 100 performs counting detection, sheath liquid is first injected into the front cell cavity 103 and the rear cell cavity 201, and the front cell electrode and the rear cell electrode are energized to make the sheath liquid a conductive medium. Since the sheath liquid is a good conductor of electricity and the tiny particles are poor conductors of electricity, when the sheath liquid containing tiny particles passes through the gem hole, the resistance on both sides of the gem hole will be significantly greater than that when no particles pass through the gem hole. In this way, the relevant information of the particles can be obtained by detecting the electrical signal generated by the change in resistance. The number of cells in the blood can be calculated by the frequency change of the electrical signal, and the type and size of the cells in the blood can be calculated by the amplitude change of the electrical signal. Among them, the sample needle group 40 is arranged toward the counting component 30, and the sample needle group 40 is used to launch the blood sample toward the counting component 30 so that the blood sample passes through the counting component 30, and the capture tube 50 is used to capture the blood sample flowing through the counting component 30.

[0072] Of course, in other embodiments, a conductor (such as a wire, etc.) may also be provided on the first connector 801 to be used as a forecell electrode. In this case, the material of the first connector 801 is a conductor or a non-conductor.

[0073] Optionally, the material of the second connector 802 , the third connector 803 , and / or the fourth connector 804 may be a conductor or a non-conductor, which will not be described in detail.

[0074] As mentioned above, the first connector 801, the second connector 802, the third connector 803 and the fourth connector 804 serve as the inlet and outlet of the cleaning liquid, and they generally need to be connected to the external pipeline. Generally, the external pipeline can be respectively sleeved on the first connector 801, the second connector 802, the third connector 803 and the fourth connector 804. However, there is a certain pressure in the liquid in the sheath flow impedance detection device 100 and the external pipeline will age after long-term use, which may cause the risk of tube detachment. Based on this, the present application further proposes a corresponding solution.

[0075] Specifically, at least one of the first joint 801 , the second joint 802 , the third joint 803 and the fourth joint 804 is provided with an anti-dropout portion to reduce the risk of the external pipeline being dropped out.

[0076] Wherein, the first joint 801 may include a first pipe 8011 connected to the front pool chamber 103, and a first anti-slip portion 8012 arranged on the end of the first pipe 8011 away from the front pool chamber 103, and the first pipe 8011 and the first anti-slip portion 8012 constitute an integrated first joint 801. The first pipe 8011 and the first anti-slip portion 8012 are both hollow tubular structures, and are roughly coaxially arranged between the two. Further, the outer diameter of the end of the first anti-slip portion 8012 connected to the first pipe 8011 is greater than the outer diameter of the first pipe 8011, so as to form an anti-slip structure between the first anti-slip portion 8012 and the first pipe 8011 to prevent the external pipe from slipping off.

[0077] Wherein, the second joint 802 may include a second pipe 8021 connected to the front pool chamber 103, and a second anti-detachment portion 8022 provided on the end of the second pipe 8021 away from the front pool chamber 103, and the second pipe 8021 and the second anti-detachment portion 8022 constitute an integral second joint 802. The second pipe 8021 and the second anti-detachment portion 8022 are both hollow tubular structures, and are roughly coaxially arranged therebetween. Further, the outer diameter of the end of the second anti-detachment portion 8022 connected to the second pipe 8021 is greater than the outer diameter of the second pipe 8021, so as to form an anti-detachment structure between the second anti-detachment portion 8022 and the second pipe 8021 to prevent the external pipe from detaching.

[0078] The third joint 803 may include a third pipe 8031 ​​connected to the rear pool cavity 201, and a third anti-slip portion 8032 disposed on the end of the third pipe 8031 ​​away from the rear pool cavity 201, and the third pipe 8031 ​​and the third anti-slip portion 8032 constitute an integrated third joint 803. The third pipe 8031 ​​and the third anti-slip portion 8032 are both hollow tubular structures, and are roughly coaxially arranged therebetween. Further, the outer diameter of the end of the third anti-slip portion 8032 connected to the third pipe 8031 ​​is greater than the outer diameter of the third pipe 8031, so as to form an anti-slip structure between the joint of the third anti-slip portion 8032 and the third pipe 8031 ​​to prevent the external pipe from slipping out of the pipe.

[0079] The fourth joint 804 may include a fourth pipe 8041 connected to the rear pool cavity 201, and a fourth anti-detachment portion 8042 provided on the end of the fourth pipe 8041 away from the rear pool cavity 201, and the fourth pipe 8041 and the fourth anti-detachment portion 8042 form an integral fourth joint 804. The fourth pipe 8041 and the fourth anti-detachment portion 8042 are both hollow tubular structures, and are roughly coaxially arranged therebetween. Further, the outer diameter of the end of the fourth anti-detachment portion 8042 connected to the fourth pipe 8041 is greater than the outer diameter of the fourth pipe 8041, so as to form an anti-detachment structure between the joint of the fourth anti-detachment portion 8042 and the fourth pipe 8041 to prevent the external pipe from detaching.

[0080] It can be understood that the above-mentioned embodiment only exemplifies the connector setting method on the sheath flow impedance detection device, but is not limited to it. The variation schemes directly derived by those skilled in the art based on the technical scheme of the present application should be understood to be within the protection scope of the present application.

[0081] See again Figure 2 and Figure 3 , the rear pool electrode 520 is arranged on the capture tube 50, and enters the rear pool cavity 201 when the capture tube 50 seals the rear pool cavity 201. Among them, the part of the rear pool electrode 520 located in the rear pool cavity 201 is arranged at a distance from the part of the capture tube 50 located in the rear pool cavity 201, that is, there is a gap space 901 between the two. Further, the rear pool electrode 520 is arranged on the side of the capture tube 50 close to the fourth joint 804, and the extension direction of the rear pool electrode 520 in the rear pool cavity 201 points to the counting component 30, and the end of the rear pool electrode 520 close to the counting component 30 does not cover the connection between the fourth joint 804 and the rear pool cavity 201. Through the above-mentioned structural arrangement, when liquid is injected into the rear pool cavity 201 through the fourth joint 804, the liquid is less resisted by the rear pool electrode 520, and the bubbles generated in the rear pool cavity can be prevented from accumulating in the gap space 901, which is conducive to the discharge of bubbles, thereby facilitating the improvement of cleaning efficiency.

[0082] The sheath flow impedance detection device provided in the embodiment of the present application can avoid the risk of misalignment between the sample needle group and the capture tube group due to the assembly tolerance between the front cell shell and the rear cell shell by respectively setting a first notch and a second notch at the opposite ends of the front cell shell, and making the sample needle group fastened to the front cell shell through the first notch, and making the capture tube fastened to the front cell shell through the second notch, thereby improving the detection counting efficiency and accuracy of the sheath flow impedance detection device.

[0083] In the actual assembly process, the front end of the capture tube is inserted into the rear pool cavity of the rear pool housing to seal the rear pool cavity, and then the docked capture tube and rear pool housing are inserted into the second notch of the front pool housing, so that the rear pool cavity of the rear pool housing communicates with the front pool cavity of the front pool housing, and then the capture tube is rotated so that the capture tube is tightly connected with the second notch, that is, the sealing effect of the capture tube on the rear pool cavity and the tight connection of the capture tube with the front pool housing are realized. The sample needle group is inserted into the first notch and cooperates with the first notch to achieve a tight connection, and the sample needle group can also seal the front pool cavity of the front pool housing.

[0084] It should be noted that the terms "include" and "have" and any variations thereof are intended to cover non-exclusive inclusions. For example, a process, method, system, product or device comprising a series of steps or units is not limited to the listed steps or units, but may optionally include steps or units not listed, or may optionally include other steps or units inherent to these processes, methods, products or devices.

[0085] The above description is only a preferred embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A sheath flow impedance detection device, characterized in that: The sheath flow impedance detection device comprises: A forebay shell, wherein the first and second slots are respectively provided at opposite ends of the forebay shell; a forebay cavity is provided in the forebay shell and is respectively connected to the first slot and the second slot; A rear pool shell, wherein a rear pool cavity is provided in the rear pool shell; the rear pool shell is inserted into the second notch so that the rear pool cavity is connected to the front pool cavity; A counting component, the counting component is arranged at the connection point between the front pool cavity and the rear pool cavity; A sample needle assembly is inserted into the front pool cavity from the first notch and faces the counting assembly; A capture tube is inserted into the rear pool cavity from the second notch and faces the counting assembly; Wherein, the sample needle group and the first notch cooperate to achieve a tight connection; the capture tube and the second notch cooperate to achieve a tight connection.

2. The sheath flow impedance detection device according to claim 1, characterized in that: One of the sample needle assembly and the first notch is provided with a first screw-in ear, and the other is provided with a first screw-in seat, and the first screw-in ear cooperates with the first screw-in seat to achieve a fastened connection; A second turn buckle ear is provided on one of the capture tube and the second notch, and a second turn buckle seat is provided on the other, and the second turn buckle ear cooperates with the second turn buckle seat to achieve a fastened connection.

3. The sheath flow impedance detection device according to claim 2, characterized in that: The first slot includes a first slot wall and a second slot wall that are arranged opposite to each other, the first screw-in seat is arranged on the first slot wall and / or the second slot wall, and the first screw-in ear is arranged on the first end cover of the sample needle group; the second slot includes a third slot wall and a fourth slot wall that are arranged opposite to each other, the second screw-in seat is arranged on the third slot wall and / or the fourth slot wall, and the second screw-in ear is arranged on the second end cover of the capture tube.

4. The sheath flow impedance detection device according to claim 3, characterized in that: The first groove wall and the second groove wall are both provided with a first turn-button seat, and the first turn-button seat on the first groove wall and the first turn-button seat on the second groove wall are staggered; The third groove wall and the fourth groove wall are both provided with a second turn-button seat, and the second turn-button seat on the third groove wall and the second turn-button seat on the fourth groove wall are staggered.

5. The sheath flow impedance detection device according to claim 3 or 4, characterized in that: The first notch also includes a first bottom wall arranged between the first groove wall and the second groove wall, the first bottom wall is provided with a first annular groove connected with the front pool cavity, the first annular groove is provided with a first sealing ring, and the sample needle group squeezes the first sealing ring to seal the front pool cavity; the second notch also includes a second bottom wall arranged between the third groove wall and the fourth groove wall, the side of the rear pool shell facing away from the second bottom wall is provided with a second annular groove connected with the rear pool cavity, the second annular groove is provided with a second sealing ring, and the capture tube squeezes the second sealing ring to seal the rear pool cavity.

6. The sheath flow impedance detection device according to claim 5, characterized in that: A receiving groove connected to the front pool cavity is provided on one side of the second bottom wall close to the rear pool shell, and an outer convex annular wall connected to the rear pool cavity is provided on one side of the rear pool shell close to the second bottom wall; the outer convex annular wall is inserted into the receiving groove, and the counting component is arranged between the receiving groove and the outer convex annular wall.

7. The sheath flow impedance detection device according to any one of claims 1 to 4, characterized in that: The sheath flow impedance detection device also includes a first joint and a second joint arranged on the front pool shell, and a third joint and a fourth joint arranged on the rear pool shell; the first joint and the second joint are respectively connected to the front pool cavity, and the third joint and the fourth joint are respectively connected to the rear pool cavity.

8. The sheath flow impedance detection device according to claim 7, characterized in that: The central axis of the connection between the first joint and the front pool cavity is perpendicular to the central axis of the front pool cavity, and the angle between the central axis of the connection between the second joint and the front pool cavity and the central axis of the front pool cavity is less than 90°; And / or, the central axis of the connection point between the third joint and the rear pool cavity is perpendicular to the central axis of the rear pool cavity, and the angle between the central axis of the connection point between the fourth joint and the rear pool cavity and the central axis of the rear pool cavity is less than 90°.

9. The sheath flow impedance detection device according to claim 8, characterized in that: A back cell electrode is provided on the capture tube, and the back cell electrode is provided on a side of the capture tube close to the fourth joint. The extension direction of the back cell electrode in the back cell cavity points to the counting component, and the end of the back cell electrode close to the counting component does not cover the connection between the fourth joint and the back cell cavity.

10. The sheath flow impedance detection device according to claim 7, characterized in that: The first joint comprises a first pipe connected to the front pool cavity, and a first anti-slip portion provided on an end of the first pipe away from the front pool cavity, wherein the outer diameter of the end of the first anti-slip portion connected to the first pipe is larger than the outer diameter of the first pipe; and / or The second joint comprises a second pipe connected to the front pool cavity, and a second anti-slip portion provided on the end of the second pipe away from the front pool cavity, the outer diameter of the end of the second anti-slip portion connected to the second pipe is larger than the outer diameter of the second pipe; and / or The third joint comprises a third pipe connected to the rear pool cavity, and a third anti-slip portion provided on the end of the third pipe away from the rear pool cavity, and the outer diameter of the end of the third anti-slip portion connected to the third pipe is larger than the outer diameter of the third pipe; and / or The fourth joint includes a fourth pipe connected to the rear pool cavity, and a fourth anti-detachment portion provided on the end of the fourth pipe away from the rear pool cavity, and the outer diameter of the end of the fourth anti-detachment portion connected to the fourth pipe is larger than the outer diameter of the fourth pipe.

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