The invention discloses a device, system and method for training upper and lower limbs. The system comprises the device for training upper and lower limbs, information processing equipment connected to the device for training upper and lower limbs, and display equipment connected to the information processing equipment. The system for training upper and lower limbs can realize high-interactivity active and passive cooperative rehabilitation training of upper and lower limbs under the induction of a virtual-reality three-dimensional training scene, realizes overall spatial perception closed-loop motion feedback from the eyes to the brain, then to the upper limbs and finally to the lower limbs, and is beneficial for improving the training participation degree of a patient. Meanwhile, the system has four modes including a constant-speed movement mode, a passive movement mode, a power-assisted movement mode and an active movement mode, so movement scenes are enriched. In addition, a human-computer interaction force can be estimated through the current change of a lower limb motor, and the torque feedback adjustment control of the lower limb motor is realized according to the interaction force, so active compliance control is realized.