Target gene methylation evaluation device

Abstract

The utility model discloses a target gene methylation evaluation device, which relates to the technical field of gene detection and comprises a base, supporting legs are fixedly mounted at four corners of the top of the base, a top frame is fixedly mounted at the tops of the supporting legs, and a supporting frame is fixedly mounted at the bottom of the top frame. And a lifting mechanism is movably mounted in the supporting frame. By adopting the structure, the first motor is used for driving the first lead screw to slide, the top plate moves up and down by spirally abutting against the sliding rod, the overall height is easily adjusted, meanwhile, a sample is very convenient to place, the sample can be automatically retracted into the detector by placing the sample in the placing frame and starting the second motor, and when the sample needs to be taken out, the sample can be conveniently taken out. And the placing frame can be easily removed through reverse driving, so that the sample taking and placing process is simplified, the overhaul and maintenance efficiency of the device is improved, the device is more convenient and flexible in the use period, and the use adaptability of the device is enhanced.

Description

Technical Field

[0001] The utility model belongs to the technical field of gene detection, and particularly relates to a target gene methylation evaluation device. Background Art

[0002] The evaluation of methylation of multiple specific target genes is a complex and delicate process, which involves the accurate detection and quantification of the methylation status of specific gene sites. Methylation is an important modification of DNA that can affect gene expression and regulation. Therefore, methylation evaluation has important application value in the fields of disease research, drug development, and personalized medicine. In the evaluation of methylation of multiple specific target genes, it is first necessary to determine the target genes and their methylation sites to be evaluated. This is usually based on the existing research foundation and experimental purpose. Once the target genes and sites are determined, the appropriate methylation detection method can be selected for evaluation;

[0003] At present, during the existing gene detection evaluation, a gene detection device needs to be used to assist in the detection. However, the existing gene detection device has certain defects and shortcomings. For example, the Chinese patent with the publication number "CN211445739U" discloses a gene detection device for safe medication for children, which includes a body and a hinge, and the interior of the body is movably connected to the door panel through the hinge. The gene detection device for safe medication for children, by providing a dust removal box, an exhaust fan and a dust hood, can exhaust air upwards through the exhaust fan, and then extract the dust inside the body outward through the dust hood, and then filter it through the filter element inside the dust removal box, so that the dust in the body can be discharged and filtered, so that the discharged gas is fresh air. By providing an adjustment rod, it is convenient to move the detection object placed on the placement plate, and it can avoid adjusting the detection position by opening the door panel after the detection object is placed. The adjustment rod is provided to adjust the position through the adjustment rod. This structure achieves the effect of convenient dust cleaning, avoids manual cleaning of the dust inside the body, and saves the time and energy required for cleaning.

[0004] Although the above-mentioned device can assist in a certain dust-proof function during use, during its specific application, the height of the overall dust hood is relatively fixed, and the dust located at the bottom of the detector is obviously difficult to be adsorbed, and the samples are generally placed at the bottom of the detector. It is obvious that the dust hood has limited dust-proof and dust-absorbing capabilities. In addition, it is not convenient to quickly take out and adjust the placed samples during use, and it is not convenient to flexibly adjust its adaptation height. The overall device cannot be flexibly adapted to people of different heights, so it needs to be improved. Utility Model Content

[0005] In view of the problems mentioned in the background technology, the purpose of the present invention is to provide a target gene methylation evaluation device to solve the problems raised by the background technology.

[0006] The above technical objectives of the utility model are achieved through the following technical solutions:

[0007] A target gene methylation assessment device comprises a base, wherein support legs are fixedly installed at the four corners of the top of the base, a top frame is fixedly installed on the top of the support legs, a support frame is fixedly installed on the bottom of the top frame, a lifting mechanism is movably installed inside the support frame, a detector body is fixedly installed on the top of the lifting mechanism, a holding mechanism is movably installed inside the detector body, a dustproof mechanism is fixedly installed on the middle of the back of the detector body, a detection mechanism is fixedly installed on the middle of the upper end of the detector body, the lower end of the detection mechanism extends to the inner side of the detector body, a sealed door is hingedly installed on the front of the detector body, a controller is fixedly installed on the lower end of the front of the sealed door, a control keyboard is fixedly installed on the top of the controller, and a display screen is fixedly installed on the upper end of the front of the sealed door;

[0008] The holding mechanism includes a movable groove and a second motor, the movable groove is opened in the middle of the bottom of the detector body, the second motor is fixedly installed at the lower end of the back of the detector body, the output end of the second motor passes through the detector body and is fixedly installed with a second screw rod, the second screw rod is rotatably connected to the inner side of the movable groove, the outer surface of the second screw rod is threadedly connected with a sliding column, and a placement frame is fixedly installed on the top of the sliding column. The base and the support legs provide a stable support foundation for the entire device to ensure the stability of the device during use. The top frame and the support frame constitute the main frame of the device and provide a platform for the installation of other components. The design of the lifting mechanism enables the detector body to move up and down, so as to adapt to different working environments and height requirements. This flexibility enables the device to perform at its best in a variety of scenarios. The detector body is the core part of the device, and it is internally installed with multiple functional modules such as a holding mechanism, a dustproof mechanism and a detection mechanism. The holding mechanism realizes automatic placement and removal of samples through components such as the movable groove, the second motor, the second screw rod and the sliding column, which greatly improves the convenience of operation.

[0009] As a preferred technical solution, the lifting mechanism includes a first motor and a base frame, the base frame is fixedly installed in the middle inner side of the support frame, the first motor is fixedly installed at the bottom of the support frame, the output end of the first motor is fixedly installed with a first screw rod, the first screw rod is rotatably connected to the inner side of the base frame, the outer surface of the first screw rod is threadedly connected with a sliding rod, the top of the sliding rod is fixedly installed with a top plate, the top of the top plate and the bottom of the detector body are fixedly connected, the base frame serves as a supporting structure of the lifting mechanism, and is fixedly installed in the middle inner side of the support frame, thereby ensuring the stability and reliability of the entire lifting mechanism, and the first motor is fixedly installed at the bottom of the support frame, providing a lifting mechanism A power source is provided. When the first motor is started, its output end drives the first screw rod to rotate. The first screw rod is rotatably connected to the inner side of the base frame, and its outer surface is connected to the slide rod by a thread. This design enables the rotation of the first screw rod to be converted into the up and down sliding of the slide rod. As the first screw rod rotates, the slide rod slides up and down on the inner side of the base frame, thereby realizing the lifting action. A top plate is fixedly installed on the top of the slide rod, and the top plate is fixedly connected to the bottom of the detector body. Therefore, when the slide rod slides up and down, the top plate moves accordingly, thereby driving the detector body to lift and lower. This design enables the lifting mechanism to flexibly adjust the height of the detector body to meet the needs of different working scenarios.

[0010] As a preferred technical solution, the lifting mechanism includes a first motor and a base frame, the base frame is fixedly installed in the middle inner side of the support frame, the first motor is fixedly installed at the bottom of the support frame, the output end of the first motor is fixedly installed with a first screw rod, the first screw rod is rotatably connected to the inner side of the base frame, the outer surface of the first screw rod is threadedly connected with a sliding rod, the top of the sliding rod is fixedly installed with a top plate, the top of the top plate and the bottom of the detector body are fixedly connected, the base frame serves as a supporting structure of the lifting mechanism, and is fixedly installed in the middle inner side of the support frame, thereby ensuring the stability and reliability of the entire lifting mechanism, and the first motor is fixedly installed at the bottom of the support frame, providing a lifting mechanism A power source is provided. When the first motor is started, its output end drives the first screw rod to rotate. The first screw rod is rotatably connected to the inner side of the base frame, and its outer surface is connected to the slide rod by a thread. This design enables the rotation of the first screw rod to be converted into the up and down sliding of the slide rod. As the first screw rod rotates, the slide rod slides up and down on the inner side of the base frame, thereby realizing the lifting action. A top plate is fixedly installed on the top of the slide rod, and the top plate is fixedly connected to the bottom of the detector body. Therefore, when the slide rod slides up and down, the top plate moves accordingly, thereby driving the detector body to lift and lower. This design enables the lifting mechanism to flexibly adjust the height of the detector body to meet the needs of different working scenarios.

[0011] As a preferred technical solution, the detection mechanism includes an electric push rod, which is fixedly installed on the top of the detector body. The output end of the electric push rod passes through the dustproof box and is fixedly installed with a base plate. Detection probes are fixedly installed at equal intervals on the bottom of the base plate. The electric push rod serves as a driving component of the detection mechanism and is fixedly installed on the top of the detector body. It has the characteristics of fast, stable and precise, and can respond quickly after receiving a control signal to push the base plate and the detection probe to move up and down. This design allows the detection mechanism to flexibly adjust the distance between the detection probe and the sample according to actual needs, thereby ensuring the accuracy and reliability of the detection process. The base plate serves as an installation platform for the detection probe, and multiple detection probes are fixedly installed at equal intervals on its bottom. This equal spacing design can ensure that each detection probe can perform uniform and comprehensive detection on the sample.

[0012] As an optimal technical solution, the dust suction component includes a connecting pipe rack, which is fixedly installed on the top of the base plate, and a hose is fixedly installed on one side of the connecting pipe rack, and the output end of the hose is connected to the dustproof box, and suction pipes are fixedly installed at equal intervals on the outside of the connecting pipe rack, and a suction hopper is fixedly installed on the bottom of the suction pipe. The connecting pipe rack is fixedly installed on the top of the base plate. As the main structure of the dust suction component, it connects the hose and each suction pipe to ensure that the airflow can flow smoothly. The output end of the hose is connected to the dustproof box to form a complete dust suction channel. When the dust suction component is started, the suction fan in the dustproof box starts to work and introduces the airflow into the connecting pipe rack through the hose. A plurality of suction pipes are fixedly installed at equal intervals on the outside of the connecting pipe rack. These suction pipes are evenly distributed and can cover a wider area, thereby more effectively removing dust. A suction hopper is fixedly installed at the bottom of each suction pipe. The shape and design of the suction hopper can ensure that dust can be sucked in to the greatest extent when approaching the sample or detection area, preventing dust from spreading to other parts of the device.

[0013] As an optimal technical solution, a sealing plate is fixedly installed on the top of the filter frame, and magnetic plates are fixedly installed on both ends of the sealing plate. The magnetic plate and the dustproof box are magnetically connected. The main function of the filter frame is to filter the airflow entering the dustproof box and effectively remove dust and impurities therein, thereby keeping the inside of the device clean and preventing dust from interfering with the detection results. Its filtering effect directly affects the performance of the dust collection component and the overall use effect of the device. The setting of the sealing plate further strengthens the sealing of the filter frame, ensuring that the airflow will not leak when passing through the filter frame, thereby improving the filtering effect. At the same time, the magnetic plates fixedly installed on both ends of the sealing plate make the installation and disassembly of the filter frame easier, and the magnetic connection design between the magnetic plate and the dustproof box not only ensures the stability of the connection, but also makes the replacement of the filter frame easy and quick.

[0014] As an optimal technical solution, both sides of the bottom of the placement frame are slidably connected with supporting strips, and both sides of the bottom of the detector body are provided with supporting grooves, and the supporting strips are slidably connected to the inside of the supporting grooves. The overall cross-sectional shapes of the supporting strips and the supporting grooves are both convex. Both sides of the bottom of the placement frame are designed with slidably connected supporting strips. This design not only enhances the stability of the placement frame, but also makes it more convenient to take and put the placement frame. When the placement frame needs to be placed or taken out, the supporting strips can slide in the supporting grooves. This sliding connection method not only ensures the stable support of the placement frame, but also allows it to make necessary displacements. The supporting grooves opened on both sides of the inner bottom of the detector body match the convex cross-sectional shape of the supporting strips. This design ensures that the supporting strips can be firmly inserted into the supporting grooves without shaking or falling off. The convex cross-sectional shape design increases the contact area and stability, so that the placement frame can be reliably supported in the detector body.

[0015] In summary, the utility model mainly has the following beneficial effects:

[0016] First, the device can flexibly adjust the height of the detector body by setting a lifting mechanism to meet the needs of different occasions. The first motor is used to drive the first screw rod to slide, and the top plate is moved up and down by the spiral contact slide rod, so as to easily adjust the overall height. At the same time, the sample placement is also very convenient. The sample is placed in the placement frame, and the second motor is started to automatically retract into the detector. When it needs to be taken out, the placement frame can be easily removed by reverse driving. This design not only simplifies the sample placement process, but also improves the inspection and maintenance efficiency of the device, making the device more convenient and flexible during use, and enhancing its use adaptability;

[0017] Second, by setting up dust prevention and detection mechanisms, the device achieves efficient detection and dust prevention functions. The electric push rod drives the bottom plate and the detection probe to move up and down, and simultaneously detects multiple samples, which is convenient for multiple specific target gene methylation evaluation and detection, and improves the detection capability. At the same time, the suction fan is started, and the air inside the detector is sucked into the dust prevention box through the hose, connecting pipe rack and suction hopper. The filter frame absorbs dust to effectively prevent dust. The electric push rod can also adjust the height of the suction hopper according to the detection requirements to achieve adaptive dust removal. This design not only ensures the detection accuracy, but also avoids the interference of dust on sample detection, and improves the overall detection performance of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0019] Figure 2 It is a rear view structural schematic diagram of the utility model;

[0020] Figure 3It is a schematic diagram of the internal structure of the detector of the utility model;

[0021] Figure 4 This is a schematic diagram of the structure of the detection mechanism of the utility model when viewed from above;

[0022] Figure 5 It is a rear structural schematic diagram of the dustproof box and the suction fan of the utility model.

[0023] 1. Base; 2. Support legs; 3. Top frame; 4. Support frame; 5. Lifting mechanism; 51. First motor; 52. Base frame; 53. First screw rod; 54. Slide rod; 55. Top plate; 6. Detector body; 7. Holding mechanism; 71. Movable slot; 72. Second motor; 73. Second screw rod; 74. Support bar; 75. Support slot; 76. Placement frame; 77. Slide column; 8. Detection mechanism; 81. Electric push rod; 82. Bottom plate; 83. Detection probe; 9. Dustproof mechanism; 91. Dustproof box; 92. Dust suction assembly; 921. Connecting pipe rack; 922. Hose; 923. Suction pipe; 924. Suction bucket; 93. Suction fan; 94. Filter frame; 95. Sealing plate; 96. Magnetic plate; 10. Sealing door; 11. Control keyboard; 12. Display screen. DETAILED DESCRIPTION

[0024] Example

[0025] refer to Figures 1 to 5 , a target gene methylation assessment device of the present embodiment comprises a base 1, support legs 2 are fixedly installed at the four corners of the top of the base 1, a top frame 3 is fixedly installed on the top of the support legs 2, a support frame 4 is fixedly installed on the bottom of the top frame 3, a lifting mechanism 5 is movably installed inside the support frame 4, a detector body 6 is fixedly installed on the top of the lifting mechanism 5, a holding mechanism 7 is movably installed inside the detector body 6, a dustproof mechanism 9 is fixedly installed on the middle part of the back of the detector body 6, a detection mechanism 8 is fixedly installed on the middle part of the upper end of the detector body 6, the lower end of the detection mechanism 8 extends to the inner side of the detector body 6, a sealed door 10 is hingedly installed on the front of the detector body 6, a controller is fixedly installed on the lower end of the front of the sealed door 10, and a control keyboard 11 is fixedly installed on the top of the controller, and a display screen 12 is fixedly installed on the upper end of the front of the sealed door 10;

[0026] The holding mechanism 7 includes a movable groove 71 and a second motor 72. The movable groove 71 is opened in the middle of the bottom of the detector body 6. The second motor 72 is fixedly installed at the lower end of the back of the detector body 6. The output end of the second motor 72 passes through the detector body 6 and is fixedly installed with a second screw rod 73. The second screw rod 73 is rotatably connected to the inner side of the movable groove 71. The outer surface of the second screw rod 73 is threadedly connected with a sliding column 77. The top of the sliding column 77 is fixedly installed with a placement frame 76. The base 1 and the support leg 2 provide a stable support foundation for the entire device to ensure the stability of the device during use. The top frame 3 and the support frame 4 constitute the main frame of the device and provide a platform for the installation of other components. The design of the lifting mechanism 5 enables the detector body 6 to move up and down, thereby adapting to different working environments and height requirements. This flexibility makes the device It can exert the best performance in various scenarios. The detector body 6 is the core part of the device. It is equipped with multiple functional modules such as the containing mechanism 7, the dustproof mechanism 9 and the detecting mechanism 8. The containing mechanism 7 realizes the automatic placement and removal of samples through the movable groove 71, the second motor 72, the second screw rod 73 and the sliding column 77 and other components, which greatly improves the convenience of operation. The existence of the dustproof mechanism 9 effectively prevents the influence of dust on the inside of the device and ensures the accuracy of the test results. The detecting mechanism 8 is responsible for the methylation evaluation of the sample and is the key to the function of the device. The design of the sealing door 10 not only protects the internal components of the device, but also makes the operation safer. The controller and the operating keyboard 11 enable the user to easily control the operation of the device, and the display screen 12 displays the test results in real time for the user to view.

[0027] refer to Figure 1-Figure 3The lifting mechanism 5 includes a first motor 51 and a base frame 52. The base frame 52 is fixedly installed in the middle of the inner side of the support frame 4. The first motor 51 is fixedly installed at the bottom of the support frame 4. The output end of the first motor 51 is fixedly installed with a first screw rod 53. The first screw rod 53 is rotatably connected to the inner side of the base frame 52. The outer surface of the first screw rod 53 is threadedly connected with a slide rod 54. The top of the slide rod 54 is fixedly installed with a top plate 55. The top of the top plate 55 is fixedly connected to the bottom of the detector body 6. The base frame 52 serves as a supporting structure of the lifting mechanism 5 and is fixedly installed in the middle of the inner side of the support frame 4 to ensure the stability and reliability of the entire lifting mechanism 5. The first motor 51 is fixedly installed at the bottom of the support frame 4 to provide a power source for the lifting mechanism 5. When the first motor 51 is started, its output end drives the first screw rod 53 to rotate. The first screw rod 53 is rotatably connected to the inner side of the base frame 52, and its outer surface is connected to the slide rod 54 through Threaded connection, this design enables the rotation of the first screw rod 53 to be converted into the up and down sliding of the slide bar 54. As the first screw rod 53 rotates, the slide bar 54 slides up and down on the inner side of the base frame 52, thereby realizing the lifting action. A top plate 55 is fixedly installed on the top of the slide bar 54, and the top plate 55 is fixedly connected to the bottom of the detector body 6. Therefore, when the slide bar 54 slides up and down, the top plate 55 moves accordingly, thereby driving the detector body 6 to rise and fall. This design enables the lifting mechanism 5 to flexibly adjust the height of the detector body 6 to meet the needs of different working scenes. In addition, the lifting mechanism 5 also has the advantages of simple structure, easy operation, and stable operation. It can perform precise height adjustment according to actual needs, thereby improving work efficiency and convenience of use. At the same time, due to the use of motor drive and screw transmission, the lifting speed and stability of the lifting mechanism 5 are well guaranteed.

[0028] refer to Figure 1-Figure 3The lifting mechanism 5 includes a first motor 51 and a base frame 52. The base frame 52 is fixedly installed in the middle of the inner side of the support frame 4. The first motor 51 is fixedly installed at the bottom of the support frame 4. The output end of the first motor 51 is fixedly installed with a first screw rod 53. The first screw rod 53 is rotatably connected to the inner side of the base frame 52. The outer surface of the first screw rod 53 is threadedly connected with a slide rod 54. The top of the slide rod 54 is fixedly installed with a top plate 55. The top of the top plate 55 is fixedly connected to the bottom of the detector body 6. The base frame 52 serves as a supporting structure of the lifting mechanism 5 and is fixedly installed in the middle of the inner side of the support frame 4 to ensure the stability and reliability of the entire lifting mechanism 5. The first motor 51 is fixedly installed at the bottom of the support frame 4 to provide a power source for the lifting mechanism 5. When the first motor 51 is started, its output end drives the first screw rod 53 to rotate. The first screw rod 53 is rotatably connected to the inner side of the base frame 52, and its outer surface is connected to the slide rod 54 through Threaded connection, this design enables the rotation of the first screw rod 53 to be converted into the up and down sliding of the slide bar 54. As the first screw rod 53 rotates, the slide bar 54 slides up and down on the inner side of the base frame 52, thereby realizing the lifting action. A top plate 55 is fixedly installed on the top of the slide bar 54, and the top plate 55 is fixedly connected to the bottom of the detector body 6. Therefore, when the slide bar 54 slides up and down, the top plate 55 moves accordingly, thereby driving the detector body 6 to rise and fall. This design enables the lifting mechanism 5 to flexibly adjust the height of the detector body 6 to meet the needs of different working scenes. In addition, the lifting mechanism 5 also has the advantages of simple structure, easy operation, and stable operation. It can perform precise height adjustment according to actual needs, thereby improving work efficiency and convenience of use. At the same time, due to the use of motor drive and screw transmission, the lifting speed and stability of the lifting mechanism 5 are well guaranteed.

[0029] refer to Figure 1-Figure 4The detection mechanism 8 includes an electric push rod 81, which is fixedly installed on the top of the detector body 6. The output end of the electric push rod 81 passes through the dustproof box 91 and is fixedly installed with a bottom plate 82. The bottom of the bottom plate 82 is fixedly installed with detection probes 83 at equal intervals. The electric push rod 81 is used as a driving component of the detection mechanism 8 and is fixedly installed on the top of the detector body 6. It has the characteristics of fast, stable and accurate. It can respond quickly after receiving the control signal to push the bottom plate 82 and the detection probe 83 to move up and down. This design allows the detection mechanism 8 to flexibly adjust the distance between the detection probe 83 and the sample according to actual needs, thereby ensuring the accuracy and reliability of the detection process. The bottom plate 82 serves as a mounting platform for the detection probe 83, and multiple detection probes 83 are fixedly installed at equal intervals at its bottom. The detection probe 83, this equally spaced design can ensure that each detection probe 83 can perform uniform and comprehensive detection on the sample, thereby improving the accuracy and consistency of the detection results. At the same time, the stability and firmness of the base plate 82 can also effectively ensure the normal operation of the detection probe 83 during the detection process, thereby avoiding errors or damage. In addition, the detection mechanism 8 is also closely integrated with the dustproof mechanism 9, and the detection probe 83 is protected by the dustproof box 91 to avoid dust and other impurities from interfering with the detection process. This design not only improves the accuracy of the detection results, but also extends the service life of the detection probe 83. The detection mechanism 8 realizes efficient and accurate evaluation of target gene methylation through the coordinated work of the electric push rod 81, the base plate 82 and the detection probe 83. The design is reasonable and the functions are complete.

[0030] refer to Figure 4The dust suction component 92 includes a connecting pipe rack 921, which is fixedly installed on the top of the bottom plate 82. A hose 922 is fixedly installed on one side of the connecting pipe rack 921. The output end of the hose 922 is connected to the dust box 91. Suction pipes 923 are fixedly installed at equal intervals on the outside of the connecting pipe rack 921. Suction buckets 924 are fixedly installed at the bottom of the suction pipes 923. The connecting pipe rack 921 is fixedly installed on the top of the bottom plate 82 as the main structure of the dust suction component 92. It connects the hose 922 and each suction pipe 923 to ensure that the airflow can flow smoothly. The output end of the hose 922 is connected to the dust box 91 to form a complete dust suction channel. When the dust suction component 92 is started, the suction fan 93 in the dust box 91 starts to work, and the airflow is introduced into the connecting pipe rack 921 through the hose 922. A plurality of suction pipes 923 are fixedly installed at equal intervals on the outside of the connecting pipe rack 921. These suction pipes 923 are divided into The dust is evenly distributed and can cover a wider area, thereby more effectively sucking out dust. A suction hopper 924 is fixedly installed at the bottom of each suction pipe 923. The shape and design of the suction hopper 924 can ensure that dust can be sucked in to the greatest extent when approaching the sample or detection area, preventing dust from spreading to other parts of the device. During the detection process, as the electric push rod 81 pushes the bottom plate 82 and the detection probe 83 up and down, the dust suction component 92 can also adaptively adjust the height of the suction hopper 924 to ensure that the dust generated in the detection area can always be effectively sucked out. This adaptive adjustment method greatly improves the practicality and efficiency of the dust suction component 92. The dust suction component 92 can effectively remove the dust generated by the target gene methylation evaluation device during the detection process through its unique design and component configuration, thereby ensuring the accuracy of the test results and the long-term stable operation of the device. This design not only improves the practicality and reliability of the device.

[0031] refer to Figure 1-Figure 3 and Figure 5A sealing plate 95 is fixedly installed on the top of the filter frame 94, and magnetic plates 96 are fixedly installed on both ends of the sealing plate 95. The magnetic plates 96 are magnetically connected to the dust box 91. The main function of the filter frame 94 is to filter the airflow entering the dust box 91, effectively remove the dust and impurities therein, thereby keeping the inside of the device clean and preventing dust from interfering with the detection results. Its filtering effect directly affects the performance of the dust collection component 92 and the overall use effect of the device. The setting of the sealing plate 95 further strengthens the sealing of the filter frame 94, ensuring that the airflow will not occur when passing through the filter frame 94. At the same time, the magnetic plates 96 fixedly installed at both ends of the sealing plate 95 make the installation and disassembly of the filter frame 94 easier. The magnetic connection design between the magnetic plate 96 and the dustproof box 91 not only ensures the stability of the connection, but also makes the replacement of the filter frame 94 easy and quick, greatly improving the convenience and efficiency of device maintenance. The design of the filter frame 94 and its related components not only improves the filtering effect of the dust suction component 92 of the target gene methylation evaluation device, but also greatly simplifies the maintenance process of the device, providing a strong guarantee for the long-term stable operation of the device.

[0032] refer to Figure 3 , both sides of the bottom of the placement frame 76 are slidably connected with supporting strips 74, and both sides of the bottom of the detector body 6 are provided with supporting grooves 75, and the supporting strips 74 are slidably connected to the inside of the supporting grooves 75. The overall cross-sectional shapes of the supporting strips 74 and the supporting grooves 75 are both convex. Both sides of the bottom of the placement frame 76 are designed with slidably connected supporting strips 74. This design not only enhances the stability of the placement frame 76, but also makes it more convenient to take and put the placement frame 76. When the placement frame 76 needs to be placed or taken out, the supporting strips 74 can slide in the supporting grooves 75. This sliding connection method not only ensures the stable support of the placement frame 76, but also allows it to make necessary displacements. The supporting grooves 75 opened on both sides of the inner bottom of the detector body 6 match the convex cross-sectional shape of the supporting strips 74. This design ensures that the supporting strips 74 can be firmly inserted into the supporting grooves 75. The convex cross-sectional shape design increases the contact area and stability, so that the placement frame 76 can be reliably supported in the detector body 6. The overall cross-sectional shape of the supporting strip 74 and the supporting groove 75 are both convex. This design not only enhances the stability of the structure, but also makes the entire device more coordinated and unified in appearance. The convex structural feature makes the movement of the supporting strip 74 in the supporting groove 75 smoother, and can also effectively prevent dust and impurities from entering the supporting groove 75, thereby ensuring the cleanliness and service life of the device. Through the sliding connection design of the supporting strip 74 and the supporting groove 75, and the application of the convex cross-sectional shape, the stability of the placement frame 76 in the detector body 6 and the convenience of taking and placing are effectively improved, and the structural stability and appearance coordination of the entire device are also enhanced.

[0033] Principle and advantages of use: By setting the lifting mechanism 5, the device can be used to start the first motor 51 to run. The first motor 51 can be used to drive the first screw rod 53 to slide on the inner side of the base frame 52. The first screw rod 53 can be assisted by the sliding rod 54 to slide up and down on the inner side of the base frame 52 through the spiral resistance of the first screw rod 53. The sliding rod 54 can assist in driving the top plate 55 to slide up and down. The top plate 55 can be assisted in adjusting the height of the entire detector body 6 by sliding the top plate 55 up and down. By adjusting the movable displacement of the detector body 6 up and down, the overall adaptation height of the device can be flexibly adjusted, and during the detection, the detection device 6 can be used to adjust the height of the entire device. During the test, the sample can be placed inside the placement frame 76. By starting the second motor 72, the second screw rod 73 can be driven to drive the slide column 77 to slide inside the movable groove 71, so that the placement frame 76 can be automatically retracted into the inside of the detector body 6. When the sample needs to be taken out, the second motor 72 is started to drive the screw rod to rotate in the reverse direction, so that the slide column 77 inside the movable groove 71 can be driven forward, and then the placement frame 76 can be automatically removed from the inside of the detector body 6, so that the device as a whole is convenient for rapid maintenance and taking and placing of sample solutions, which can improve the convenience of use and the adaptability of the device during overall use;

[0034] By arranging the dustproof mechanism 9 to cooperate with the detection mechanism 8, the device can be used in the process of use by starting the electric push rod 81 to push the bottom plate 82 to move up and down. The bottom plate 82 can be moved up and down to assist in pushing the detection probe 83 to move up and down. The detection probe 83 can be inserted into the placement frame 76 through the up and down movement. The detection probe 83 is arranged at equal intervals, and it can simultaneously detect multiple detection samples in the placement frame 76, which can improve the overall detection capability of the device. In addition, during the detection process, the suction fan 93 can be started to run. The suction fan 93 can assist in the suction of the inside of the detector body 6 through the hose 922, the connecting pipe rack 921 and the suction bucket 924 at the bottom of the suction pipe 923. Air is sucked into the interior of the dustproof box 91, and the dust is assisted by the filter frame 94 inside the dustproof box 91, which can play a good dust-proof role, and as the electric push rod 81 pushes the bottom plate 82 to move up and down, the suction bucket 924 can be adaptively adjusted to move up and down during the detection process, so that the suction and dust removal of the device can adaptively adjust the height, and can suction and dust the interior of the detector body 6 to the greatest extent, and can prevent dust and impurities from affecting the detection conditions inside the placement frame 76, and can improve the overall detection performance of the device, and when disassembly and maintenance are required, only the sealing plate 95 needs to be lifted to remove the filter frame 94, and the setting of the magnetic suction plate 96 can adsorb and fix the sealing plate 95, which can improve its overall stability and facilitate the use of the device.

Claims

1. A target gene methylation assessment device, comprising a base (1), characterized in that: Support legs (2) are fixedly mounted at the four corners of the top of the base (1), a top frame (3) is fixedly mounted on the top of the support legs (2), a support frame (4) is fixedly mounted on the bottom of the top frame (3), a lifting mechanism (5) is movably mounted inside the support frame (4), a detector body (6) is fixedly mounted on the top of the lifting mechanism (5), a containing mechanism (7) is movably mounted inside the detector body (6), a dustproof mechanism (9) is fixedly mounted on the middle of the back of the detector body (6), a detection mechanism (8) is fixedly mounted on the middle of the upper end of the detector body (6), the lower end of the detection mechanism (8) extends to the inner side of the detector body (6), a sealing door (10) is hingedly mounted on the front of the detector body (6), a controller is fixedly mounted on the lower end of the front of the sealing door (10), and a control keyboard (11) is fixedly mounted on the top of the controller, and a display screen (12) is fixedly mounted on the upper end of the front of the sealing door (10); The containing mechanism (7) comprises a movable groove (71) and a second motor (72), wherein the movable groove (71) is arranged in the middle of the bottom of the detector body (6), the second motor (72) is fixedly mounted on the lower end of the back of the detector body (6), the output end of the second motor (72) passes through the detector body (6) and is fixedly mounted with a second screw rod (73), the second screw rod (73) is rotatably connected to the inner side of the movable groove (71), the outer surface of the second screw rod (73) is threadedly connected with a slide column (77), and a placement frame (76) is fixedly mounted on the top of the slide column (77); The dustproof mechanism (9) comprises a dustproof box (91) and a dust suction assembly (92); the dustproof box (91) is fixedly mounted on the middle of the back of the detector body (6); a suction fan (93) is fixedly mounted on the back of the dustproof box (91); an input end of the suction fan (93) is connected to the inside of the dustproof box (91); the dust suction assembly (92) is fixedly mounted on the outside of the detection mechanism (8); and a filter frame (94) is slidably connected to the inside of the dustproof box (91); The detection mechanism (8) comprises an electric push rod (81), the electric push rod (81) is fixedly mounted on the top of the detector body (6), the output end of the electric push rod (81) passes through the dustproof box (91) and is fixedly mounted with a bottom plate (82), and detection probes (83) are fixedly mounted at equal intervals on the bottom of the bottom plate (82); The dust collection assembly (92) comprises a connecting pipe rack (921), wherein the connecting pipe rack (921) is fixedly mounted on the top of the bottom plate (82), a hose (922) is fixedly mounted on one side of the connecting pipe rack (921), an output end of the hose (922) is connected to the dustproof box (91), suction pipes (923) are fixedly mounted at equal intervals on the outside of the connecting pipe rack (921), and a suction hopper (924) is fixedly mounted on the bottom of the suction pipe (923).

2. A target gene methylation assessment device according to claim 1, characterized in that: The lifting mechanism (5) comprises a first motor (51) and a base frame (52), wherein the base frame (52) is fixedly mounted on the inner middle part of the support frame (4), the first motor (51) is fixedly mounted on the bottom of the support frame (4), a first screw rod (53) is fixedly mounted on the output end of the first motor (51), the first screw rod (53) is rotatably connected to the inner side of the base frame (52), a sliding rod (54) is threadedly connected to the outer surface of the first screw rod (53), a top plate (55) is fixedly mounted on the top of the sliding rod (54), and the top of the top plate (55) is fixedly connected to the bottom of the detector body (6).

3. A target gene methylation assessment device according to claim 2, characterized in that: A sealing plate (95) is fixedly mounted on the top of the filter frame (94), and magnetic plates (96) are fixedly mounted on both ends of the sealing plate (95), and the magnetic plates (96) are magnetically connected to the dustproof box (91).

4. A target gene methylation assessment device according to claim 1, characterized in that: Both sides of the bottom of the placement frame (76) are slidably connected with support bars (74), and both sides of the bottom of the detector body (6) are provided with support grooves (75), and the support bars (74) are slidably connected to the inside of the support grooves (75), and the overall cross-sectional shapes of the support bars (74) and the support grooves (75) are both convex.

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