Cell suspension collecting device

By designing a cell suspension acquisition device containing a thermosol insulator and a semiconductor refrigeration sheet, low-temperature storage is realized, solving the problem of short cell storage time in the prior art and extending the survival time of cells.

CN222455040UActive Publication Date: 2025-02-11TIANJIN MAILUO MEDICAL LAB CO LTD
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Patent Information

Application Number
CN202420850403.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-23
Publication Date
2025-02-11
Estimated Expiration
2034-04-23

AI Technical Summary

Technical Problem

The lack of a low-temperature storage structure in the prior art leads to the inability to reduce the cell metabolism rate, which easily causes cells to age and die, thereby affecting the storage time of cells.

Method used

A cell suspension collection device including a thermostatic chamber, a thermostatic cover, a key controller, a heat insulation pad, a thermal conductivity box, a liquid storage test tube, a temperature sensor, a semiconductor refrigeration sheet, a heat dissipation fin and a heat dissipation fan were designed, and it was automatically Control semiconductor refrigeration sheets and heat dissipation fans to achieve low temperature storage and extend the storage time of cells.

Benefits of technology

It effectively reduces the metabolic rate of cells, extends the storage time of cells, and avoids the problems of cells aging and death due to lack of low-temperature storage structures.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a cell suspension collection device, which belongs to the technical field of cell suspension collection and comprises a thermal insulation box, a thermal insulation cover is movably hinged to the right side face of the thermal insulation box, a key controller is fixedly connected to the left side face of the thermal insulation box, and a thermal insulation pad and a cooling fan are fixedly connected to the inner wall of the thermal insulation box respectively. The inner wall of the heat insulation pad is fixedly connected with a heat conduction box. According to the cell suspension collection device, through mutual cooperation of the thermal insulation box, the thermal insulation cover, the key controller, the thermal insulation pad, the heat conduction box, the liquid storage test tube, the temperature sensor, the semiconductor chilling plate, the heat dissipation fins and the heat dissipation fan, the thermal insulation box, the thermal insulation cover and the thermal insulation pad have a good thermal insulation function, and cell suspension can be stored in the liquid storage test tube; a storage temperature range required by cells in the device can be set by operating the key controller, so that when the temperature sensor monitors that the temperature in the heat conduction box is higher than the temperature range, the key controller can automatically control the upper surface of the semiconductor chilling plate to refrigerate the heat conduction box.
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Description

Technical Field

[0001] The present application belongs to the technical field of cell suspension collection, and in particular, relates to a cell suspension collection device. Background Art

[0002] Cell suspension collection refers to the process of obtaining cells from the tissues, organs or other sources of an organism through specific methods and techniques, and suspending them in a suitable liquid medium to form a cell suspension. It provides an important means for biological and medical research, which can help us better understand the characteristics and functions of cells and provide strong support for the diagnosis and treatment of diseases. The key is to maintain the integrity and activity of cells for subsequent analysis and research, and the process requires the use of corresponding cell suspension collection devices.

[0003] The utility model with the existing authorization announcement number CN220098966U discloses a cell suspension collection device. By setting the cooperation between the placement port, the movable port, the sealing ring, the movable rod and the driving part, the epidermis separated from the patient's normal skin can be evenly stored. During storage, the epidermis can be fully immersed in the culture medium for reaction, which is convenient for the subsequent pinching and transplantation of the epidermis. By setting the cooperation between the installation port, the limit spring, the limit block and the limit port, the movable rod can be limited, and there is no need to manually hold the pull rod all the time, which further facilitates the acquisition of the melanocyte epidermis, saves time and effort, and is highly practical.

[0004] Although the above technical solution facilitates uniform storage of cells and is easy to access, it lacks a low-temperature storage structure, which makes it impossible to reduce the cell metabolism rate and easily causes cell aging and death, thereby affecting the storage time of the cells.

[0005] To this end, we proposed a cell suspension collection device to solve the above problems. Utility Model Content

[0006] The purpose of the present application is to solve the problem in the prior art that the cell metabolism rate cannot be reduced, which easily causes cell aging and death, thereby affecting the storage time of the cells, and to propose a cell suspension collection device.

[0007] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0008] A cell suspension collection device comprises a thermal insulation box, the right side of the thermal insulation box is movably hinged with a thermal insulation cover, the left side of the thermal insulation box is fixedly connected to a button controller, the inner walls of the thermal insulation box are respectively fixedly connected with a thermal insulation pad and a heat dissipation fan, the inner wall of the thermal insulation pad is fixedly connected with a heat conduction box, a plurality of identical liquid storage test tubes are arranged inside the thermal conduction box, the inner wall of the thermal conduction box is fixedly connected with a temperature sensor, the bottom surface of the thermal conduction box and the inner wall of the thermal insulation box are jointly fixedly connected with a semiconductor refrigeration sheet, and the bottom surface of the semiconductor refrigeration sheet is fixedly connected with heat dissipation fins.

[0009] Preferably, the bottom surface of the thermally conductive box is fixedly connected to the inner bottom wall of the thermal isolation box, the outer surface of each of the liquid storage test tubes is in contact with the inner wall of the thermally conductive box, the temperature sensor, semiconductor refrigeration sheet and heat dissipation fan are electrically connected to the button controller through wires, and two groups of pads are fixedly connected to the bottom surface of the thermal isolation box, and two anti-slip pads are fixedly connected to the bottom surface of each group of pads.

[0010] Preferably, two fixing rods are fixedly connected to the left side of the thermal insulation box, and two limiting rods are fixedly connected to the left side of the thermal insulation cover.

[0011] Preferably, two limit plates are provided on the left side of the temperature isolation box, the inner wall of each limit plate is rotatably connected to the outer surface of the fixing rod, and the interior of each limit plate is clamped with the outer surface of the limit rod.

[0012] Preferably, the front side and the back side of the thermal insulation box are both fixedly connected with a pull shell, and the inner wall of each pull shell is fixedly connected with a pull rod.

[0013] Preferably, a handle is provided inside each of the pull shells, and the inner wall of each handle is rotatably connected to the outer surface of the pull rod.

[0014] In summary, the technical effects and advantages of this application are:

[0015] Through the mutual cooperation of the temperature insulation box, the temperature insulation cover, the button controller, the insulation pad, the thermal conductive box, the liquid storage tube, the temperature sensor, the semiconductor refrigerator, the heat sink fins and the heat sink fan, the temperature insulation box, the temperature insulation cover and the insulation pad have good heat insulation function, the cell suspension can be stored in the liquid storage tube, the operation button controller can set the storage temperature range required for the cells in the device, and then when the temperature sensor detects that the temperature in the thermal conductive box is higher than the temperature range, the button controller can automatically control the upper surface of the semiconductor refrigerator to cool the thermal conductive box, and the button controller automatically controls the heat sink fan to exhaust downward, and cooperates with the heat sink fins to accelerate the heat dissipation of the bottom heating surface of the semiconductor refrigerator, until the temperature sensor detects that the temperature in the thermal conductive box is in the temperature range set by the button controller, which plays the role of low-temperature storage of cell suspension and increases the cell storage time, avoiding the problem that the lack of low-temperature storage structure makes it impossible to reduce the cell metabolic rate, which easily causes cell aging and death, thereby affecting the storage time of the cells. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a three-dimensional overall structural schematic diagram of the cell suspension collection device of the utility model;

[0017] Figure 2 It is a three-dimensional structural schematic diagram of the thermal insulation box of the utility model;

[0018] Figure 3 It is a schematic diagram of the structure of the utility model of the heat insulation box cut into three dimensions;

[0019] Figure 4 It is a schematic diagram of the three-dimensional structure of the thermal insulation box of the utility model when viewed from the side.

[0020] In the figure: 1. Insulation box; 2. Insulation cover; 3. Button controller; 4. Insulation pad; 5. Heat conduction box; 6. Liquid storage tube; 7. Temperature sensor; 8. Semiconductor refrigeration plate; 9. Heat dissipation fin; 10. Heat dissipation fan; 11. Fixing rod; 12. Limit rod; 13. Limit plate; 14. Pad; 15. Anti-slip pad; 16. Pull shell; 17. Pull rod; 18. Handle. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0022] Reference Figure 1-4A cell suspension collection device comprises a temperature-isolating box 1, a temperature-isolating cover 2 is movably hinged on the right side of the temperature-isolating box 1, a button controller 3 is fixedly connected to the left side of the temperature-isolating box 1, two groups of pads 14 are fixedly connected to the bottom of the temperature-isolating box 1, and two anti-skid pads 15 are fixedly connected to the bottom of each group of pads 14. By providing the pads 14, the bottom of the temperature-isolating box 1 can be raised, thereby facilitating air circulation at the bottom of the temperature-isolating box 1, thereby cooperating with other structures to help the cooling and heat dissipation process of the entire collection device. By providing the anti-skid pads 15, the friction of the bottom of the pads 14 can be increased, thereby increasing the stability of the entire collection device when placed.

[0023] The inner walls of the thermal insulation box 1 are respectively fixedly connected with a thermal insulation pad 4 and a heat dissipation fan 10, the inner wall of the thermal insulation pad 4 is fixedly connected with a heat conduction box 5, the bottom surface of the heat conduction box 5 is fixedly connected to the inner bottom wall of the thermal insulation box 1, the left side surface of the thermal insulation box 1 is fixedly connected with two fixing rods 11, and the left side surface of the thermal insulation cover 2 is fixedly connected with two limiting rods 12. By providing the fixing rods 11, a rotation base surface can be provided for other limiting structures, and by providing the limiting rods 12, the above-mentioned limiting structures can be limited.

[0024] A number of identical liquid storage tubes 6 are arranged inside the heat-conducting box 5, and a temperature sensor 7 is fixedly connected to the inner wall of the heat-conducting box 5. The outer surface of each liquid storage tube 6 is in contact with the inner wall of the heat-conducting box 5. Two limit plates 13 are arranged on the left side of the thermal insulation box 1. The inner wall of each limit plate 13 is rotatably connected to the outer surface of the fixed rod 11, and the interior of each limit plate 13 is snapped with the outer surface of the limit rod 12. By setting the limit plate 13, it can rotate around the outer surface of the fixed rod 11 and then snap-fit ​​with the outer surface of the limit rod 12, thereby increasing the closing tightness and sealing of the thermal insulation cover 2 and the thermal insulation box 1.

[0025] The bottom surface of the heat-conducting box 5 and the inner wall of the temperature-isolating box 1 are fixedly connected with a semiconductor refrigeration plate 8. The temperature sensor 7, the semiconductor refrigeration plate 8 and the heat dissipation fan 10 are electrically connected to the button controller 3 through wires. The front and the back of the temperature-isolating box 1 are fixedly connected with a pull shell 16. The inner wall of each pull shell 16 is fixedly connected with a pull rod 17. By providing the pull rod 17, a rotation base surface can be provided for the hand-gripping structure in the pull shell 16, thereby increasing the flexibility of use of the hand-gripping structure. By providing the pull shell 16 and the pull rod 17, the above-mentioned hand-gripping structure can be cooperated to lift and carry the entire collection device.

[0026] The bottom surface of the semiconductor refrigeration plate 8 is fixedly connected with the heat dissipation fins 9, and a handle 18 is provided inside each pull shell 16. The inner wall of each handle 18 is rotatably connected to the outer surface of the pull rod 17. By providing the handle 18, it can be rotated around the outer surface of the pull rod 17 inside the pull shell 16, thereby facilitating the lifting and carrying of the entire collection device.

[0027] The working principle of the utility model is as follows: when in use, according to the characteristics of the cells to be collected, first operate the button controller 3 to control the ambient temperature in the heat conduction box 5, and operate the button controller 3 to activate the temperature monitoring function of the temperature sensor 7. When the temperature sensor 7 detects that the temperature in the heat conduction box 5 is higher than the temperature range set by the button controller 3, the button controller 3 controls the semiconductor refrigeration sheet 8 to be powered on and the upper surface of the semiconductor refrigeration sheet 8 begins to cool the heat conduction box 5. At the same time, the heat dissipation fins 9 accelerate the heat dissipation of the bottom heat dissipation surface of the semiconductor refrigeration sheet 8, and the button controller 3 controls the heat dissipation fan 10 to be powered on to start accelerating the heat dissipation of the heat dissipation fins 9, until the temperature sensor 7 detects that the ambient temperature of the heat conduction box 5 is close to the low temperature limit of the temperature range set by the button controller 3, and the button controller 3 can stop the semiconductor refrigeration The cooling surface of the sheet 8 faces the cooling of the heat conduction box 5, and then the limit plate 13 is moved to rotate around the fixed rod 11 and away from the limit rod 12, the insulation cover 2 is flipped up and away from the insulation box 1, and an appropriate amount of cell culture fluid is placed in each liquid storage tube 6, and then the cell tissue to be suspended and stored is put into the corresponding liquid storage tube 6 as evenly and in an appropriate amount as possible, and the liquid storage tube 6 containing the cell suspension can be taken out of the heat conduction box 5, shaken and then put into the heat conduction box 5, and finally, the insulation cover 2 and the insulation box 1 are tightly closed, and the limit plate 13 is moved to rotate around the fixed rod 11 and then engaged with the limit rod 12. The design of the entire cell suspension collection device effectively solves the problem that the lack of a low-temperature storage structure makes it impossible to reduce the cell metabolic rate, which easily causes cell aging and death, thereby affecting the storage time of the cells.

[0028] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0029] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present utility model, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0030] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A cell suspension collection device, comprising an incubator (1), characterized in that: The right side of the thermal insulation box (1) is movably hinged with a thermal insulation cover (2), the left side of the thermal insulation box (1) is fixedly connected with a button controller (3), the inner wall of the thermal insulation box (1) is respectively fixedly connected with a thermal insulation pad (4) and a heat dissipation fan (10), the inner wall of the thermal insulation pad (4) is fixedly connected with a heat conduction box (5), a plurality of identical liquid storage test tubes (6) are arranged inside the thermal conduction box (5), the inner wall of the thermal conduction box (5) is fixedly connected with a temperature sensor (7), the bottom surface of the thermal conduction box (5) and the inner wall of the thermal insulation box (1) are jointly fixedly connected with a semiconductor cooling plate (8), and the bottom surface of the semiconductor cooling plate (8) is fixedly connected with a heat dissipation fin (9).

2. A cell suspension collection device according to claim 1, characterized in that: The bottom surface of the heat-conducting box (5) is fixedly connected to the inner bottom wall of the thermal isolation box (1); the outer surface of each of the liquid storage test tubes (6) is in contact with the inner wall of the heat-conducting box (5); the temperature sensor (7), the semiconductor refrigeration sheet (8) and the heat dissipation fan (10) are electrically connected to the key controller (3) through wires; two groups of pads (14) are fixedly connected to the bottom surface of the thermal isolation box (1); and the bottom surface of each group of pads (14) is fixedly connected to two anti-slip pads (15).

3. A cell suspension collection device according to claim 1, characterized in that: The left side of the thermal insulation box (1) is fixedly connected to two fixing rods (11), and the left side of the thermal insulation cover (2) is fixedly connected to two limiting rods (12).

4. A cell suspension collection device according to claim 3, characterized in that: Two limit plates (13) are arranged on the left side of the temperature isolation box (1), the inner wall of each limit plate (13) is rotatably connected to the outer surface of the fixing rod (11), and the interior of each limit plate (13) is clamped with the outer surface of the limit rod (12).

5. A cell suspension collection device according to claim 1, characterized in that: The front side of the thermal insulation box (1) and the back side of the thermal insulation box (1) are both fixedly connected with a pull shell (16), and the inner wall of each pull shell (16) is fixedly connected with a pull rod (17).

6. A cell suspension collection device according to claim 5, characterized in that: A handle (18) is provided inside each of the pull shells (16), and the inner wall of each of the handles (18) is rotatably connected to the outer surface of the pull rod (17).

Citation Information

Patent Citations

  • Cell suspension collection equipment

    CN220098966U