Fermentation device for preparing porous material of artificial bone scaffold

By setting up high-efficiency filters and ultraviolet disinfection lamps in the intake pipe of the fermentation device, the problem of microbial contamination in traditional fermentation devices is solved, and the biocompatibility and safety guarantee of the porous materials of artificial bone stents is achieved.

CN222476573UActive Publication Date: 2025-02-14HUAFENG DINGYE (BEIJING) TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202420788961.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-16
Publication Date
2025-02-14
Estimated Expiration
2034-04-16

AI Technical Summary

Technical Problem

Traditional fermentation devices have a risk of microbial contamination when preparing artificial bone stent porous materials, which may pose a potential threat to the biocompatibility and safety of the materials.

Method used

A fermentation device for the preparation of porous materials of artificial bone stents is designed, including a fermentation tube and an outlet tube on the outer wall of the fermentation tank, and a disinfection component is provided inside the intake tube. The disinfection component includes a high-efficiency filter and an ultraviolet disinfection lamp to Remove dust, suspended microorganisms, bacteria, viruses, etc. from the gas.

Benefits of technology

Through the design of this device, microbial contamination in the gas is effectively removed, the safety and stability of the fermentation process are ensured, and the biocompatibility and safety of the porous materials of artificial bone stents are ensured.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a fermentation device for preparing a porous material of an artificial bone scaffold, which comprises a fermentation tank, an air inlet pipe is fixedly communicated with the outer wall of the fermentation tank, and the air inlet pipe and an air outlet pipe are arranged on the outer wall of the fermentation tank and used for providing necessary oxygen and carbon dioxide exchange for the porous material of the artificial bone scaffold in the fermentation process. According to the present invention, the sterilization assembly is arranged in the gas inlet pipe, such that the gas needing to enter the fermentation tank through the gas inlet pipe is firstly filtered through the high efficiency filter so as to remove the dust and the suspended microorganisms in the gas; the filtered gas is disinfected by the ultraviolet disinfection lamp, bacteria, viruses and the like possibly existing in the gas can be effectively removed, so that the safety and the stability of the fermentation process are guaranteed, and the stirring assembly is arranged, so that uniform mixing of the raw materials and smooth proceeding of the fermentation process are facilitated.
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Description

Technical Field

[0001] The utility model relates to the technical field of artificial bone scaffold preparation, in particular to a fermentation device for preparing porous materials of artificial bone scaffolds. Background Art

[0002] With the growing demand for bone defect repair in the medical field, traditional bone defect repair methods can no longer meet clinical needs. In the preparation process of artificial bone scaffold materials, fermentation technology has attracted much attention due to its unique advantages. Fermentation technology can utilize the metabolic activities of microorganisms to prepare materials with specific structures and properties through biosynthesis under specific environmental conditions. For the preparation of porous materials for artificial bone scaffolds, fermentation technology can achieve precise regulation of the material microstructure, thereby meeting the requirements of bone defect repair for material performance.

[0003] However, traditional fermentation devices have some limitations when preparing porous materials for artificial bone scaffolds. For example, traditional fermentation devices require oxygen and carbon dioxide exchange during the preparation process, and there may be a risk of microbial contamination inside the air inlet pipe, which may cause potential threats to the biocompatibility and safety of the materials during subsequent fermentation. Therefore, we need to propose a fermentation device for preparing porous materials for artificial bone scaffolds. Utility Model Content

[0004] The utility model aims to provide a fermentation device for preparing porous materials of artificial bone scaffolds, aiming to solve the problem that the fermentation device in the prior art may have the risk of microbial contamination during the preparation process, posing a potential threat to the biocompatibility and safety of the material.

[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0006] A fermentation device for preparing porous materials for artificial bone scaffolds comprises a fermentation tank, an air inlet pipe is fixedly connected to the outer wall of the fermentation tank, an air outlet pipe is fixedly connected to the side of the fermentation tank away from the air inlet pipe, a disinfection component for sterilizing the gas entering the fermentation tank is arranged inside the air inlet pipe, and a stirring component for fully mixing the raw materials for preparing the artificial bone scaffold is arranged inside the fermentation tank.

[0007] Preferably, the disinfection component includes a high-efficiency filter, and the high-efficiency filter is arranged inside the air intake pipe. The air intake pipe is fixedly connected to an ultraviolet disinfection lamp on one side of the high-efficiency filter.

[0008] Preferably, two groups of slide grooves are symmetrically opened on the inner wall of the air intake pipe, and two groups of sliders matching the slide grooves are symmetrically fixedly connected to the outer wall of the high-efficiency filter. The two groups of sliders are respectively slidably connected to the inside of the two groups of slide grooves, and the two groups of sliders are bolted and fixed to the air intake pipe by fixing screws.

[0009] Preferably, two groups of fixing seats are symmetrically fixed on the outer wall of the air intake pipe, threaded through holes are respectively opened on the outer walls of the two groups of fixing seats, threaded blind holes corresponding to the threaded through holes are respectively opened on the outer walls of the two groups of sliding blocks, and one ends of the two groups of fixing screws respectively pass through the two groups of threaded through holes and the air intake pipe threads in sequence and are connected to the inside of the two groups of threaded blind holes.

[0010] Preferably, the stirring assembly includes a rotating rod, the top end of which is rotatably mounted on the inner top of the fermentation tank, the top end of the rotating rod passes through the fermentation tank and is connected to a drive motor, and a stirring paddle is fixedly connected to the outer wall of the rotating rod.

[0011] Preferably, the driving motor is fixedly mounted on the top of the fermentation tank, and one end of the output shaft of the driving motor is fixedly connected to the top end of the rotating rod.

[0012] Preferably, the top of the fermentation tank is fixedly connected with a feed pipe, and the bottom of the fermentation tank is fixedly connected with a discharge pipe.

[0013] Compared with the prior art, the beneficial effects of the utility model are:

[0014] The utility model provides an air inlet pipe and an air outlet pipe on the outer wall of the fermentation tank to provide necessary oxygen and carbon dioxide exchange for the artificial bone scaffold porous material during the fermentation process to maintain the normal growth and metabolism of microorganisms. A disinfection component is arranged inside the air inlet pipe, so that the gas that needs to enter the fermentation tank through the air inlet pipe is first filtered by a high-efficiency filter to remove dust and suspended microorganisms in the gas. The filtered gas is then disinfected by an ultraviolet disinfection lamp to effectively remove bacteria, viruses, etc. that may be present in the gas, thereby ensuring the safety and stability of the fermentation process. The provision of a stirring component is conducive to promoting uniform mixing of raw materials and smooth progress of the fermentation process. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of the structure of the utility model;

[0016] Figure 2 This is a schematic diagram of the structure of the stirring assembly of the utility model;

[0017] Figure 3 It is a structural schematic diagram of the air intake pipe and the disinfection component of the utility model.

[0018] In the figure: 1. fermentation tank; 2. air inlet pipe; 3. air outlet pipe; 4. disinfection component; 401. high efficiency filter; 402. ultraviolet disinfection lamp; 5. stirring component; 501. rotating rod; 502. driving motor; 503. stirring paddle; 6. slide groove; 7. slider; 8. fixing seat; 9. threaded through hole; 10. threaded blind hole; 11. feed pipe; 12. discharge pipe. DETAILED DESCRIPTION

[0019] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0020] See also Figure 1-3 , the utility model provides a technical solution:

[0021] A fermentation device for preparing porous materials for artificial bone scaffolds, comprising a fermentation tank 1, an air inlet pipe 2 is fixedly connected to the outer wall of the fermentation tank 1, an air outlet pipe 3 is fixedly connected to the side of the fermentation tank 1 away from the air inlet pipe 2, a disinfection component 4 for sterilizing the gas entering the fermentation tank is arranged inside the air inlet pipe 2, a stirring component 5 for fully mixing the raw materials for preparing the artificial bone scaffold is arranged inside the fermentation tank 1, the disinfection component 4 comprises a high-efficiency filter 401, the high-efficiency filter 401 is arranged inside the air inlet pipe 2, and an ultraviolet disinfection lamp 402 is fixedly connected to the air inlet pipe 2 on one side of the high-efficiency filter 401. The invention provides an air inlet pipe 2 and an air outlet pipe 3 on the outer wall of the fermentation tank 1 to provide necessary oxygen and carbon dioxide exchange for the artificial bone scaffold porous material during the fermentation process to maintain the normal growth and metabolism of microorganisms. A disinfection component is provided inside the air inlet pipe 2 so that the gas entering the fermentation tank 1 through the air inlet pipe 2 is first filtered by a high-efficiency filter 401 to remove dust and suspended microorganisms in the gas. The filtered gas is then disinfected by an ultraviolet disinfection lamp 402 to effectively remove bacteria, viruses, etc. that may be present in the gas, thereby ensuring the safety and stability of the fermentation process.

[0022] Two groups of slide grooves 6 are symmetrically provided on the inner wall of the air inlet pipe 2, and two groups of sliders 7 adapted to the slide grooves 6 are symmetrically fixedly connected to the outer wall of the high efficiency filter 401. The two groups of sliders 7 are slidably connected to the inside of the two groups of slide grooves 6, and the two groups of sliders 7 are bolted and fixed to the air inlet pipe 2 by fixing screws.

[0023] Two sets of fixing seats 8 are symmetrically fixedly installed on the outer wall of the air intake pipe 2, and threaded through holes 9 are respectively opened on the outer walls of the two sets of fixing seats 8. Threaded blind holes 10 corresponding to the threaded through holes 9 are respectively opened on the outer walls of the two sets of sliders 7. One ends of the two sets of fixing screws respectively pass through the two sets of threaded through holes 9 and the air intake pipe 2 in sequence and are threadedly connected to the inside of the two sets of threaded blind holes 10.

[0024] Specifically, when the high efficiency filter 401 needs to be disassembled for maintenance or replacement, the two sets of fixing screws can be removed first, and then the high efficiency filter 401 can be directly pulled out to complete the disassembly work, so that the high efficiency filter 401 has the characteristic of being easy to disassemble and assemble;

[0025] The stirring assembly 5 includes a rotating rod 501, the top of which is rotatably mounted on the inner top of the fermentation tank 1, the top of which passes through the fermentation tank 1 and is connected to a driving motor 502, and a stirring paddle 503 is fixedly connected to the outer wall of the rotating rod 501;

[0026] The driving motor 502 is fixedly installed on the top of the fermentation tank 1, and one end of the output shaft of the driving motor 502 is fixedly connected to the top of the rotating rod 501;

[0027] Specifically, by setting the driving motor 502, the rotating rod 501 and the stirring paddle 503 for coordinated use, the output shaft of the driving motor 502 drives the rotating rod 501 to rotate, thereby driving the stirring paddle 503 to rotate, thereby achieving the effect of mixing and stirring the raw materials inside the fermentation tank 1, which is conducive to promoting uniform mixing of the raw materials and smooth fermentation process;

[0028] A feed pipe 11 is fixedly connected to the top of the fermentation tank 1, and the porous raw materials of the artificial bone scaffold can enter the fermentation tank 1 through the feed pipe 11 for fermentation treatment. A discharge pipe 12 is fixedly connected to the bottom of the fermentation tank 1, and the fermented raw materials can be discharged through the discharge pipe 12. A control system (not shown in the figure) is also provided inside the fermentation tank 1. The control system includes a temperature control system, a humidity control system and a pressure control system, etc., which can realize the precise adjustment of various parameters during the fermentation process of the porous raw materials of the artificial bone scaffold. Through the control system, the data of the fermentation process can be monitored and recorded in real time. During the fermentation process of the porous raw materials of the artificial bone scaffold, it is necessary to regularly observe and record the changes of various parameters for timely adjustment.

[0029] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A fermentation device for preparing porous materials for artificial bone scaffolds, comprising a fermentation tank (1), characterized in that: An air inlet pipe (2) is fixedly connected to the outer wall of the fermentation tank (1); an air outlet pipe (3) is fixedly connected to the side of the fermentation tank (1) away from the air inlet pipe (2); a disinfection component (4) for sterilizing the gas entering the fermentation tank is arranged inside the air inlet pipe (2); and a stirring component (5) for fully mixing the raw materials for preparing the artificial bone scaffold is arranged inside the fermentation tank (1).

2. The fermentation device for preparing porous materials of artificial bone scaffolds according to claim 1, characterized in that: The disinfection component (4) comprises a high-efficiency filter (401), wherein the high-efficiency filter (401) is arranged inside the air intake pipe (2), and an ultraviolet disinfection lamp (402) is fixedly connected to one side of the air intake pipe (2) located on the high-efficiency filter (401).

3. The fermentation device for preparing porous materials of artificial bone scaffolds according to claim 2, characterized in that: Two groups of slide grooves (6) are symmetrically provided on the inner wall of the air intake pipe (2), and two groups of sliders (7) adapted to the slide grooves (6) are symmetrically fixedly connected to the outer wall of the high-efficiency filter (401). The two groups of sliders (7) are respectively slidably connected to the inside of the two groups of slide grooves (6), and the two groups of sliders (7) are bolted and fixed to the air intake pipe (2) by fixing screws.

4. The fermentation device for preparing porous materials of artificial bone scaffolds according to claim 3, characterized in that: Two groups of fixing seats (8) are symmetrically fixedly installed on the outer wall of the air intake pipe (2), and threaded through holes (9) are respectively opened on the outer walls of the two groups of fixing seats (8). Threaded blind holes (10) corresponding to the threaded through holes (9) are respectively opened on the outer walls of the two groups of sliding blocks (7), and one end of the two groups of fixing screws respectively penetrates the two groups of threaded through holes (9) and the air intake pipe (2) in sequence and is threadedly connected to the inside of the two groups of threaded blind holes (10).

5. The fermentation device for preparing porous materials of artificial bone scaffolds according to claim 1, characterized in that: The stirring assembly (5) comprises a rotating rod (501), the top end of which is rotatably mounted on the inner top of the fermentation tank (1), the top end of which passes through the fermentation tank (1) and is connected to a driving motor (502), and a stirring paddle (503) is fixedly connected to the outer wall of the rotating rod (501).

6. A fermentation device for preparing porous materials of artificial bone scaffolds according to claim 5, characterized in that: The driving motor (502) is fixedly mounted on the top of the fermentation tank (1), and one end of the output shaft of the driving motor (502) is fixedly connected to the top end of the rotating rod (501).

7. The fermentation device for preparing porous materials of artificial bone scaffolds according to claim 1, characterized in that: The top of the fermentation tank (1) is fixedly connected to a feed pipe (11), and the bottom of the fermentation tank (1) is fixedly connected to a discharge pipe (12).