Heat exchange device for biological pharmacy
By using partition components and protective components in the biopharmaceutical heat exchange device, the problems of uneven heat exchange, low cooling efficiency and difficult dirt in the prior art are solved, and more efficient cooling and more stable exchange are achieved Thermal effect.
Patent Information
- Application Number
- CN202420736855.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-11
- Publication Date
- 2025-02-14
- Estimated Expiration
- 2034-04-11
AI Technical Summary
The existing heat exchange devices have problems such as uneven heat exchange, low cooling efficiency, high energy consumption, and difficulty in cleaning dirt and scale during the biopharmaceutical process.
A heat exchange device for biopharmaceuticals is designed, using partition components and protective components. The partition components achieve uniform cooling of the drug liquid through an annular partition plate and a square tube. The protective components achieve cleaning of the partition plate through the roof plate, connecting rod and cleaning brush. .
Through the design of partition components, uniform cooling of the medicine liquid is achieved, cooling efficiency is improved, cooling time and energy consumption is reduced; through the design of protective components, the accumulation of dirt and scale is effectively avoided, and the heat exchange effect is maintained.
Smart Images
Figure CN222481232U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of biopharmaceuticals, in particular to a heat exchange device for biopharmaceuticals. Background Art
[0002] A heat exchange device is a device that transfers heat from one fluid to another. In the biopharmaceutical process, a heat exchanger is needed to heat the drug solution to achieve thermal sterilization and ensure the sterility of the drug solution, or to use a heat exchanger to cool the injection solution to lower the product temperature and maintain the stability of the drug properties, as well as to heat starch paste, etc. Heat exchange is an important link in pharmaceutical production.
[0003] Existing heat exchange devices mostly use shell-and-tube heat exchangers. Due to their structure, the shell and tube are located in the middle of the liquid medicine, and the reserved space on the upper and lower sides is large. The depth of the liquid medicine is deep, which can easily lead to uneven heat exchange. When cooling the injection liquid, etc., the heat exchange efficiency is low, so the required cooling time is long and the energy consumption is high. At the same time, the liquid medicine and water flowing through the heat exchanger are prone to produce dirt and scale, which is not easy to clean. In addition, the dirt or scale accumulates for a long time and adheres to the inner wall of the heat exchange tube, which will increase the thickness of the heat exchange tube and affect the heat exchange effect.
[0004] To this end, we propose a heat exchange device for biopharmaceuticals. Utility Model Content
[0005] The utility model provides a heat exchange device for biopharmaceuticals.
[0006] To achieve the above object, the utility model provides the following technical solution: a heat exchange device for biopharmaceuticals, comprising a shell assembly, a partition assembly is fixedly connected to the interior of the shell assembly, and a protective assembly is rotatably connected to the upper surface of the partition assembly;
[0007] The partition assembly includes a partition plate, one side of which is fixedly connected to the inside of the shell assembly, a groove is provided on the lower surface of the partition plate, a square tube is fixedly connected to the inside of the groove, and a bottom plate is fixedly connected to the lower surface of the square tube.
[0008] Preferably, there are several partition plates, which are annular and equidistantly arranged in a sleeve-type manner from large to small; the partition plates have uniform thickness to maintain a consistent thermal conductivity effect, and a square tube is fixedly connected inside the groove on the lower surface of every two partition plates to facilitate the entry and exit of the medicine solution.
[0009] Preferably, the shell assembly includes an anti-corrosion layer, the interior of the anti-corrosion layer is fixedly connected to the outer surface of the partition plate, the outer surface of the anti-corrosion layer is fixedly connected to the thermal insulation layer, and the outer surface of the thermal insulation layer is fixedly connected to the outer shell; the anti-corrosion layer prevents the chemical solution from corroding the thermal insulation layer and causing temperature loss, and the thermal insulation layer facilitates maintaining a relatively constant temperature inside the outer shell to avoid being affected by the external temperature, which makes it difficult to control the heat exchange time, and the outer shell protects the outside of the thermal insulation layer to prevent external collisions from damaging the thermal insulation layer.
[0010] Preferably, the protective assembly includes a top plate, the lower surface of the top plate is rotatably connected to the lower surface of the partition plate, the lower surface of the top plate is fixedly connected to a connecting rod, the outer surface of the connecting rod is fixedly connected to a cleaning brush, and the outer surface of the top plate is fixedly connected to a turning handle; the turning handle is held to rotate the top plate, so that the connecting rod drives the cleaning brush to rotate, and the two sides of the partition plate where the medicine liquid and cold water flow through are scrubbed to prevent dirt or scale from forming on the inner wall of the partition plate, which increases the thickness of the partition plate, resulting in a decrease in the temperature conduction effect and affecting the heat exchange effect. At the same time, a circular groove consistent with the bottom plate is opened on the upper surface of the top plate to facilitate the entry of cold water.
[0011] Preferably, the lower surface of the shell assembly is fixedly connected to a bottom cover, the upper surface of the protective assembly is rotatably connected to a top cover, and the middle part of the lower surface of the bottom cover and the middle part of the upper surface of the top cover are fixedly connected to connecting ports; the connecting port on the upper surface of the top cover is externally connected to a cold water supplier, and cold water enters the top cover through the connecting port, flows into between the partition plates corresponding to the through grooves opened on the top plate, and then flows into the bottom cover through the through grooves opened on the bottom plate, and then flows out through the connecting port on the lower surface of the bottom cover, thereby realizing cold water circulation.
[0012] Preferably, a leg is fixedly connected to the edge of the lower surface of the bottom cover, and an anti-skid pad is fixedly connected to the bottom end of the leg; the anti-skid pad improves the stability of the leg placement to prevent the device from tipping over, and the leg places the shell assembly at a suitable height, making it convenient for the operator to connect a drain pipe to the connection port on the lower surface of the bottom cover to collect the cold water after heat exchange.
[0013] Preferably, a sealing cover is inserted into one end of the square tube, and a sealing gasket is fixedly connected to the inside of the sealing cover; the sealing cover facilitates sealing of the square tube to prevent dust and the like from entering the medicine storage area through the square tube when not in use and causing pollution to the medicine storage area, and the sealing gasket improves the sealing performance.
[0014] Compared with the prior art, the beneficial effects of the utility model are:
[0015] 1. The utility model provides a partition assembly, wherein the number of partition boards is several, the thickness is uniform, and the partition boards are equidistantly arranged. A square tube is fixedly connected to the groove on the lower surface of each two partition boards. The upper surface of the bottom and top boards is provided with several through grooves, and the top board is provided with a through groove corresponding to the bottom board. Cold water is added through the connecting port between the partition boards corresponding to the through grooves, and the injection liquid required for cooling is added through the square tube between the partition boards corresponding to the ports of the square tubes, so that the cold water and the medicine liquid between the partition boards are arranged at intervals, which is convenient for cooling both sides of the medicine liquid by cold water at the same time, and the heat exchange is uniform, thereby improving the efficiency of cooling the injection liquid, etc., to reduce the cooling time and reduce energy consumption.
[0016] 2. The utility model provides a protective component, and the top plate is driven to rotate by holding the handle, so that the connecting rod drives the cleaning brush to rotate, and the two sides of the partition plate where the liquid medicine and cold water flow through are scrubbed to prevent dirt or scale from forming on the inner wall of the partition plate, which increases the thickness of the partition plate, resulting in a decrease in the temperature conduction effect and affecting the heat exchange effect. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 It is a schematic diagram of the overall structure of the utility model;
[0018] Figure 2 It is a schematic cross-sectional structure diagram of the utility model as a whole;
[0019] Figure 3 This is a schematic diagram of the structure of the housing assembly of the utility model;
[0020] Figure 4 This is a schematic diagram of the partition assembly structure of the utility model.
[0021] In the figure: 1. Shell assembly; 101. Anti-corrosion layer; 102. Insulation layer; 103. Shell; 2. Partition assembly; 201. Partition board; 202. Square tube; 203. Bottom plate; 3. Protection assembly; 301. Top plate; 302. Connecting rod; 303. Cleaning brush; 304. Turning handle; 4. Bottom cover; 5. Top cover; 6. Connection port; 7. Leg. DETAILED DESCRIPTION
[0022] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0023] Example 1
[0024] See also Figure 1-4, a heat exchange device for biopharmaceuticals shown in the figure includes a shell component 1, a partition component 2 is fixedly connected to the inside of the shell component 1, and a protection component 3 is rotatably connected to the upper surface of the partition component 2;
[0025] The partition assembly 2 includes a partition plate 201, one side of which is fixedly connected to the inside of the shell assembly 1, a groove is provided on the lower surface of the partition plate 201, a square tube 202 is fixedly connected inside the groove, and a bottom plate 203 is fixedly connected to the lower surface of the square tube 202.
[0026] In this embodiment: there are several partition plates 201 with uniform thickness and equidistant arrangement. A square tube 202 is fixedly connected to the inside of the groove on the lower surface of every two partition plates 201. Several through grooves are provided on the upper surface of the bottom plate 203. A through groove corresponding to the bottom plate 203 is provided on the top plate 301. Cold water is added between the partition plates 201 corresponding to the through grooves through the connecting port 6. The injection liquid required for cooling is added between the partition plates 201 corresponding to the ports of the square tube 202 through the square tube 202. The cold water and the medicine liquid between the partition plates 201 are arranged at intervals, which is convenient for cooling both sides of the medicine liquid by cold water at the same time, and the heat exchange is uniform, thereby improving the efficiency of cooling the injection liquid, etc., to reduce the cooling time and reduce energy consumption.
[0027] See also Figure 1 , Figure 2 and Figure 4 In the figure, there are several partition plates 201, which are ring-shaped and are equidistantly arranged in a sleeve-type manner from large to small.
[0028] In this embodiment: the partition plates 201 have a uniform thickness to maintain a uniform temperature conduction effect, and a square tube 202 is fixedly connected inside the grooves on the lower surfaces of every two partition plates 201, and the square tube 202 facilitates the entry and exit of the drug solution.
[0029] Working principle: First, the anti-corrosion layer 101 prevents the chemical solution from corroding the thermal insulation layer 102 and causing temperature loss. The thermal insulation layer 102 is convenient for maintaining a relatively constant temperature inside the shell 103 to avoid being affected by the external temperature, which makes it difficult to control the heat exchange time. The shell 103 protects the outside of the thermal insulation layer 102 to prevent external collisions from damaging the thermal insulation layer 102. Then, the connection port 6 on the upper surface of the top cover 5 is externally connected to a cold water supplier. Through this connection port 6, cold water enters the interior of the top cover 5, flows into the partition plates 201 corresponding to the through grooves opened on the top plate 301, and then flows into the bottom cover 4 through the through grooves opened on the bottom plate 203, and then flows out through the connection port 6 on the lower surface of the bottom cover 4 to realize cold water circulation. Secondly, there are several partition plates 201 with uniform thickness and equidistant arrangement. A square tube 202 is fixedly connected to the grooves on the lower surfaces of every two partition plates 201. The bottom plate 203 A plurality of through grooves are provided on the upper surface, and a through groove corresponding to the bottom plate 203 is provided on the top plate 301. Cold water is added between the partition plates 201 corresponding to the through grooves through the connecting port 6, and the injection liquid required for cooling is added between the partition plates 201 corresponding to the ports of the square tube 202 through the square tube 202, so that the cold water and the medicine liquid between the partition plates 201 are arranged at intervals, which is convenient for cooling both sides of the medicine liquid by cold water at the same time, and the heat exchange is uniform, thereby improving the efficiency of cooling the injection liquid, etc., so as to reduce the cooling time and reduce energy consumption. Finally, when it needs to be cleaned, the handle 304 is held by hand to drive the top plate 301 to rotate, so that the connecting rod 302 drives the cleaning brush 303 to rotate, and the two sides of the partition plate 201 where the medicine liquid and the cold water flow are scrubbed to avoid dirt or scale forming on the inner wall of the partition plate 201, which increases the thickness of the partition plate 201, resulting in a decrease in the temperature conduction effect and affecting the heat exchange effect.
[0030] Example 2
[0031] See also Figure 1 , Figure 2 , Figure 3 and Figure 4 This embodiment further explains Example 1. In the figure, the shell assembly 1 includes an anti-corrosion layer 101. The inside of the anti-corrosion layer 101 is fixedly connected to the outer surface of the partition plate 201. The outer surface of the anti-corrosion layer 101 is fixedly connected to the insulation layer 102. The outer surface of the insulation layer 102 is fixedly connected to the outer shell 103.
[0032] In this embodiment: the anti-corrosion layer 101 prevents the chemical solution from corroding the insulation layer 102 and causing temperature loss. The insulation layer 102 facilitates maintaining a relatively constant temperature inside the shell 103 to avoid being affected by the external temperature, which makes it difficult to control the heat exchange time. The shell 103 protects the outside of the insulation layer 102 to avoid damage to the insulation layer 102 caused by external collisions.
[0033] See also Figure 1 , Figure 2 and Figure 4 In the figure, the protective component 3 includes a top plate 301, the lower surface of the top plate 301 is rotatably connected to the lower surface of the partition plate 201, the lower surface of the top plate 301 is fixedly connected to a connecting rod 302, the outer surface of the connecting rod 302 is fixedly connected to a cleaning brush 303, and the outer surface of the top plate 301 is fixedly connected to a turning handle 304.
[0034] In this embodiment: the handle 304 is held by hand to drive the top plate 301 to rotate, so that the connecting rod 302 drives the cleaning brush 303 to rotate, and the two sides of the partition plate 201 where the medicine and cold water flow through are scrubbed to prevent dirt or scale from forming on the inner wall of the partition plate 201, which increases the thickness of the partition plate 201, resulting in a decrease in the temperature conduction effect and affecting the heat exchange effect. At the same time, a circular groove consistent with the bottom plate 203 is opened on the upper surface of the top plate 301 to facilitate the entry of cold water.
[0035] See also Figure 1 and Figure 2 In the figure, the lower surface of the shell component 1 is fixedly connected with a bottom cover 4, the upper surface of the protection component 3 is rotatably connected with a top cover 5, and the middle part of the lower surface of the bottom cover 4 and the middle part of the upper surface of the top cover 5 are fixedly connected with a connecting port 6.
[0036] In this embodiment: the connection port 6 on the upper surface of the top cover 5 is externally connected to a cold water supplier, through which cold water enters the interior of the top cover 5, flows through the through grooves opened on the top plate 301 into between the partition plates 201 corresponding to the through grooves, and then flows through the through grooves opened on the bottom plate 203 into the bottom cover 4, and then flows out through the connection port 6 on the lower surface of the bottom cover 4, thereby realizing cold water circulation.
[0037] Example 3
[0038] See also Figure 1 and Figure 2 As shown in the figure, a leg 7 is fixedly connected to the edge of the lower surface of the bottom cover 4, and an anti-slip pad is fixedly connected to the bottom end of the leg 7.
[0039] In this embodiment: the anti-skid pad improves the stability of the support leg 7 to prevent the device from tipping over. The support leg 7 places the shell assembly 1 at a suitable height, which is convenient for the operator to connect the drain pipe to the connection port 6 on the lower surface of the bottom cover 4 to collect the cold water after heat exchange.
[0040] See also Figure 1 , Figure 2 and Figure 4 In the figure, a sealing cover is inserted into one end of the square tube 202, and a sealing gasket is fixedly connected to the inside of the sealing cover.
[0041] In this embodiment: the sealing cover facilitates sealing of the square tube 202 to prevent dust and the like from entering the medicine storage area through the square tube 202 when not in use, thereby contaminating the medicine storage area, and the sealing gasket improves the sealing performance.
[0042] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include"-"comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process-method-article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process-method-article or device.
[0043] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A heat exchange device for biopharmaceuticals, characterized in that: It comprises a shell component (1), the interior of the shell component (1) is fixedly connected to a partition component (2), and the upper surface of the partition component (2) is rotatably connected to a protection component (3); The partition assembly (2) comprises a partition plate (201), one side of the partition plate (201) is fixedly connected to the interior of the shell assembly (1), a groove is provided on the lower surface of the partition plate (201), a square tube (202) is fixedly connected to the interior of the groove, and a bottom plate (203) is fixedly connected to the lower surface of the square tube (202).
2. A biopharmaceutical heat exchange device according to claim 1, characterized in that: The number of the partition plates (201) is several, and the partition plates (201) are ring-shaped and are arranged equidistantly in a sleeve-type manner from large to small.
3. A heat exchange device for biopharmaceuticals according to claim 1, characterized in that: The shell assembly (1) comprises an anti-corrosion layer (101), the interior of the anti-corrosion layer (101) is fixedly connected to the outer surface of the partition plate (201), the outer surface of the anti-corrosion layer (101) is fixedly connected to the thermal insulation layer (102), and the outer surface of the thermal insulation layer (102) is fixedly connected to the outer shell (103).
4. A biopharmaceutical heat exchange device according to claim 1, characterized in that: The protection component (3) comprises a top plate (301), the lower surface of the top plate (301) is rotatably connected to the lower surface of the partition plate (201), the lower surface of the top plate (301) is fixedly connected to a connecting rod (302), the outer surface of the connecting rod (302) is fixedly connected to a cleaning brush (303), and the outer surface of the top plate (301) is fixedly connected to a turning handle (304).
5. A biopharmaceutical heat exchange device according to claim 1, characterized in that: The lower surface of the shell component (1) is fixedly connected to a bottom cover (4), the upper surface of the protection component (3) is rotatably connected to a top cover (5), and the middle part of the lower surface of the bottom cover (4) and the middle part of the upper surface of the top cover (5) are both fixedly connected to a connection port (6).
6. A heat exchange device for biopharmaceuticals according to claim 5, characterized in that: A support leg (7) is fixedly connected to the edge of the lower surface of the bottom cover (4), and an anti-slip pad is fixedly connected to the bottom end of the support leg (7).
7. A biopharmaceutical heat exchange device according to claim 1, characterized in that: A sealing cover is inserted into one end of the square tube (202), and a sealing gasket is fixedly connected inside the sealing cover.