Pipetting workstation
By designing automatic moving sample tubes and a pipetting workstation that achieves drip protection, the problems of low automation and liquid contamination in the prior art are solved, and the operation efficiency and equipment cleanliness are improved.
Patent Information
- Application Number
- CN202421149540.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-24
- Publication Date
- 2025-02-18
- Estimated Expiration
- 2034-05-24
AI Technical Summary
The existing pipetting workstations have low degree of automation and require manual operation. They are prone to dripping liquid during the pipetting process, causing contamination of samples and equipment.
A pipetting workstation including a rack, a sample tube rack, a sample tube operating unit, a gun head rack and a pipetting unit are designed. The workstation automatically moves the sample tube and opens the screw cap through the first moving mechanism and the robot assembly; through the second moving mechanism, the pipette handle and the anti-drip assembly, the liquid is absorbed and discharged, and passes through the waste liquid pallet Carry dripping liquid to prevent contamination.
It improves the automation level of the pipetting workstation, reduces manual operation, avoids the problem of liquid contamination of samples and equipment, and provides greater operating space, which facilitates the removal and replacement of sample tube racks and gun head racks.
Smart Images

Figure CN222490115U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of liquid transfer, in particular to a liquid transfer workstation. Background Art
[0002] In biochemical laboratories, due to the complexity of the research objects, it is necessary to frequently draw liquid samples, transfer liquid samples to designated locations, and inject liquid samples into containers. This process is mostly done manually, which is inefficient, labor-intensive, time-consuming and labor-intensive. To solve this problem, some existing technologies process liquid samples through a pipetting workstation.
[0003] The pipetting workstation includes a moving mechanism and a pipette placed on the moving mechanism, the pipette includes a pipette handle and a gun head, the liquid sample is sucked by the pipette, the liquid sample is transferred by the moving mechanism, and then the liquid sample is injected into the container by the pipette. However, in the operation of the existing pipetting workstation, some processes need to be operated manually, the degree of automation is low, and during the pipetting process, the liquid in the pipette may drip and contaminate the sample and the equipment. Utility Model Content
[0004] The utility model aims to provide a liquid transfer workstation with a high degree of automation. During the liquid transfer process, liquid will not contaminate samples and equipment. In addition, the operation space is large, which is convenient for manual disassembly and replacement of sample tube racks and gun tip racks.
[0005] To achieve this purpose, the utility model adopts the following technical solutions:
[0006] A liquid transfer workstation, comprising:
[0007] A frame, comprising a base and a side plate arranged on one side of the base;
[0008] A sample tube rack, arranged on the base, for placing sample tubes;
[0009] The sample tube operation unit comprises a first moving mechanism and a manipulator assembly, wherein the first moving mechanism is arranged on the side plate, and the manipulator assembly is arranged at the output end of the first moving mechanism, and the manipulator assembly is used to grab the sample tube, and after the first moving mechanism moves the sample tube to a position to be clamped and clamps it, the manipulator assembly is used to open the screw cap of the sample tube;
[0010] A gun tip rack, arranged on the base, for placing the gun tip;
[0011] The pipetting unit includes a second moving mechanism, a pipette handle and an anti-drip component, wherein the second moving mechanism is arranged on the side panel, the pipette handle is arranged at the output end of the second moving mechanism, and the pipette handle can be connected or separated from the gun head; the anti-drip component includes a waste liquid supporting plate, one end of the waste liquid supporting plate is rotatably connected to the second moving mechanism, and the other end of the waste liquid supporting plate can be located below the gun head after being connected to the pipette handle, so as to carry liquid dripping during the pipetting process.
[0012] Preferably, the first moving mechanism comprises an X-axis moving component, a Y-axis moving component and a Z-axis moving component connected in sequence, the X-axis moving component is arranged on the side plate, and the Y-axis moving component can move along the X-axis direction on the X-axis moving component; the Z-axis moving component moves along the Y-axis direction on the Y-axis moving component; the manipulator component is arranged on the Z-axis moving component and can move along the Z-axis direction on the Z-axis moving component; the X-axis direction is the length direction of the side plate, and the X-axis direction, the Y-axis direction and the Z-axis direction are perpendicular to each other.
[0013] Preferably, the X-axis moving assembly includes an X-axis driving member, an X-axis synchronous belt, an X-axis sliding plate and an X-axis slide rail. The X-axis driving member and the X-axis slide rail are both arranged on the side plate. The output end of the X-axis driving member is transmission-connected to the X-axis synchronous belt. The X-axis sliding plate is fixed on the X-axis synchronous belt and is slidingly connected to the X-axis slide rail.
[0014] Preferably, the X-axis driving member is arranged on a side of the side plate away from the sample tube rack, and an output end of the X-axis driving member passes through the side plate and is connected to the X-axis synchronous belt transmission.
[0015] Preferably, the Y-axis moving assembly includes a Y-axis driving member and a Y-axis output member, the Y-axis driving member is arranged on a side of the side plate away from the sample tube rack, the side plate is provided with a penetration groove along the X-axis direction, and the Y-axis driving member is fixed to the X-axis sliding plate through the penetration groove; the output end of the Y-axis driving member penetrates the X-axis sliding plate and is transmission-connected to the Y-axis output member.
[0016] Preferably, the Y-axis driving member is slidably connected to the penetration groove.
[0017] Preferably, the pipetting workstation further comprises a waste gun tip box, which is arranged on the base and has a feed port for discarding used gun tips.
[0018] Preferably, at least two clamping parts are provided at the bottom of the pipette handle along the circumferential direction, and at least two of the clamping parts can enter the gun tip through the connecting port at the upper end of the gun tip and be clamped with the clamping groove of the gun tip; the feed port includes a first opening and a second opening, the second opening is connected to the first opening, the gun tip can enter the waste gun tip box through the first opening, the size of the second opening is smaller than the outer diameter of the connecting port of the gun tip, and the pipette handle can be separated from the gun tip through the second opening.
[0019] Preferably, the anti-drip assembly further comprises a driving member and a connecting rod, wherein the driving member is arranged on the second moving mechanism, the connecting rod is connected to the output end of the driving member, and one end of the waste liquid support plate is detachably connected to the connecting rod.
[0020] Preferably, the structure of the second moving mechanism is the same as that of the first moving mechanism.
[0021] Beneficial effects of the utility model:
[0022] The utility model provides a pipetting workstation, including a frame, a sample tube rack, a sample tube operation unit, a gun head rack and a pipetting unit, wherein the frame includes a base and a side plate arranged on one side of the base; the sample tube rack and the gun head rack are both arranged on the base; the sample tube operation unit includes a first moving mechanism and a manipulator assembly, and the pipetting unit includes a second moving mechanism, a pipetting gun handle and an anti-drip assembly; the anti-drip assembly includes a waste liquid support plate. The pipetting workstation has a high degree of automation. When working, the sample tube is moved to a position to be clamped and the screw cap is in an open state through the cooperation of the first moving mechanism and the manipulator assembly; after the pipetting gun handle is clamped with the gun head, the second moving mechanism moves the pipetting gun handle and the gun head to a position to be clamped to absorb the liquid in the sample tube, and then moves the liquid to a position to be discharged to discharge the liquid, after which the pipetting gun handle is separated from the gun head, and finally the screw cap of the sample tube is tightened by the first moving mechanism, and the sample tube is put back into the sample tube rack. During the pipetting process, the liquid dripping during the pipetting process is carried by the waste liquid support plate, and the sample and the equipment will not be contaminated. In addition, the first moving mechanism and the second moving mechanism are both arranged on the side panel, so that the staff has a large operating space, which is convenient for disassembly and replacement of the sample tube rack and the gun tip rack, and convenient for observing the operation of the pipetting workstation. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] Figure 1 It is a structural schematic diagram of the liquid transfer workstation provided by the utility model;
[0024] Figure 2 It is a structural schematic diagram of the liquid transfer workstation (installation part of the housing) provided by the utility model;
[0025] Figure 3It is a schematic diagram of the first viewing angle of the first moving mechanism involved in the utility model;
[0026] Figure 4 It is a schematic diagram of the structure of the first moving mechanism involved in the utility model from a second viewing angle;
[0027] Figure 5 It is a schematic diagram of the structure of the second moving mechanism involved in the utility model from a first viewing angle;
[0028] Figure 6 It is a schematic diagram of the second viewing angle of the second moving mechanism involved in the utility model;
[0029] Figure 7 It is a partial structural exploded diagram of the manipulator assembly involved in the utility model;
[0030] Figure 8 It is a structural schematic diagram of the base involved in the utility model;
[0031] Fig. 9 It is a structural schematic diagram of the anti-drip assembly involved in the utility model.
[0032] In the figure:
[0033] 1. frame; 11. base; 12. side panel; 121. penetration groove; 13. housing; 131. first housing; 132. second housing; 133. third housing;
[0034] 2. Sample tube rack;
[0035] 3. Sample tube operation unit; 31. First moving mechanism; 311. X-axis moving assembly; 3111. X-axis driving member; 3112. X-axis synchronous belt; 3113. X-axis sliding plate; 3114. X-axis slide rail; 312. Y-axis moving assembly; 3121. Y-axis driving member; 3122. Y-axis output member; 3123. Y-axis fixing plate; 3124. Y-axis sliding plate; 3125. Y-axis sliding plate rail; 313, Z-axis moving assembly; 3131, Z-axis fixing plate; 3132, Z-axis driving member; 3133, Z-axis synchronous pulley; 3134, Z-axis lead screw; 3135, Z-axis sliding plate; 3136, Z-axis slide rail; 314, photoelectric switch; 32, manipulator assembly; 321, base; 3211, T-slot; 322, claw; 3221, T-sliding block; 3222, clamping head;
[0036] 4. Gun head rack;
[0037] 5. Liquid transfer unit; 51. Second moving mechanism; 52. Liquid transfer gun handle; 53. Anti-drip assembly; 531. Waste liquid support plate; 532. Driving member; 533. Connecting rod;
[0038] 6. Electrical drag chain;
[0039] 8. Waste gun tip box; 81. Feed inlet;
[0040] 9. Deep hole plate;
[0041] 10. Clamping mechanism;
[0042] 100. Sample tube; 101. Screw cap. DETAILED DESCRIPTION
[0043] The present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It is to be understood that the specific embodiments described herein are only used to explain the present invention, rather than to limit the present invention. It should also be noted that, for ease of description, only the parts related to the present invention, rather than all structures, are shown in the accompanying drawings.
[0044] In the description of the present invention, unless otherwise clearly specified and limited, the terms "connected", "connected", and "fixed" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0045] In the present utility model, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may include that the first and second features are in direct contact, or may include that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, a first feature being "above", "above" and "above" a second feature includes that the first feature is directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below", "below" and "below" a second feature includes that the first feature is directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.
[0046] In the description of this embodiment, the terms "upper", "lower", "right", etc., are based on the directions or positions shown in the drawings, and are only for the convenience of description and simplified operation, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation of the present invention. In addition, the terms "first" and "second" are only used to distinguish in the description and have no special meaning.
[0047] like Figures 1 to 9As shown, the utility model provides a pipetting workstation, which includes a rack 1, a sample tube rack 2, a sample tube operating unit 3, a gun head rack 4 and a pipetting unit 5. The rack 1 includes a base 11 and a side plate 12 arranged on one side of the base 11; the sample tube rack 2 is arranged on the base 11 and is used to place a sample tube 100; the sample tube operating unit 3 includes a first moving mechanism 31 and a manipulator assembly 32, the first moving mechanism 31 is arranged on the side plate 12, the manipulator assembly 32 is arranged at the output end of the first moving mechanism 31, the manipulator assembly 32 is used to grab the sample tube 100, and the sample tube 100 is moved to a position to be clamped and clamped by the first moving mechanism 31. Afterwards, the manipulator assembly 32 is used to open the screw cap 101 of the sample tube 100; the gun tip rack 4 is arranged on the base 11 for placing the gun tip; the pipetting unit 5 includes a second moving mechanism 51, a pipette gun handle 52 and an anti-drip assembly 53, the second moving mechanism 51 is arranged on the side plate 12, the pipette gun handle 52 is arranged at the output end of the second moving mechanism 51, and the pipette gun handle 52 can be connected to or separated from the gun tip; the anti-drip assembly 53 includes a waste liquid support plate 531, one end of the waste liquid support plate 531 is rotatably connected to the second moving mechanism 51, and the other end of the waste liquid support plate 531 can be located below the gun tip after being connected to the pipette gun handle 52, so as to carry the liquid dripping during the pipetting process.
[0048] The degree of automation of the liquid transfer workstation is relatively high. When working, the sample tube 100 on the sample tube rack 2 is grasped by the manipulator assembly 32, and the sample tube 100 is moved to the position to be clamped by the first moving mechanism 31. After the sample tube 100 is clamped at the position to be clamped, the manipulator assembly 32 opens the screw cap 101 of the sample tube 100; at the same time, the pipette gun handle 52 is clamped with the gun head, and the pipette gun handle 52 and the gun head are moved to the position to be clamped by the second moving mechanism 51 to absorb the liquid in the sample tube 100, and then the liquid is moved to the position to be discharged to discharge the liquid, and then the pipette gun handle 52 is separated from the gun head, and finally the screw cap 101 of the sample tube 100 is tightened by the manipulator assembly 32, and the sample tube 100 is put back into the sample tube rack 2 by the first moving mechanism 31. Similarly, the liquids in other sample tubes 100 on the sample tube rack 2 are transferred by the above operation.
[0049] After the pipette gun handle 52 is engaged with the gun head to absorb the liquid, during the pipetting process until the gun head is separated from the pipette gun handle 52 and discarded, the waste liquid support plate 531 carries the liquid dripping during the pipetting process, and will not contaminate the sample and the equipment. When the pipette gun handle 52 is engaged with the gun head, when the gun head is discharging liquid at the position to be discharged, and when the pipette gun handle 52 is separated from the gun head, the waste liquid support plate 531 is rotated to other positions without affecting the work of these three stations. In addition, the first moving mechanism 31 and the second moving mechanism 51 are both arranged on the side plate 12, which saves space, increases the operating space for the staff, facilitates the disassembly and replacement of the sample tube rack 2 and the gun head rack 4 at multiple positions, and facilitates the observation of the operation of the pipetting workstation.
[0050] Optionally, in this embodiment, the first moving mechanism 31 includes an X-axis moving component 311, a Y-axis moving component 312, and a Z-axis moving component 313 connected in sequence, the X-axis moving component 311 is arranged on the side plate 12, the Y-axis moving component 312 can move along the X-axis direction on the X-axis moving component 311; the Z-axis moving component 313 moves along the Y-axis direction on the Y-axis moving component 312; the manipulator component 32 is arranged on the Z-axis moving component 313, and can move along the Z-axis direction on the Z-axis moving component 313; the X-axis direction is the length direction of the side plate 12, and the X-axis direction, the Y-axis direction, and the Z-axis direction are perpendicular to each other. The X-axis moving component 311, the Y-axis moving component 312, and the Z-axis moving component 313 can realize the movement of the manipulator component 32 to different positions in the space on one side of the side plate 12.
[0051] Optionally, in this embodiment, if Figure 3 and Figure 4 As shown, the X-axis moving assembly 311 includes an X-axis driving member 3111, an X-axis synchronous belt 3112, an X-axis sliding plate 3113 and an X-axis slide rail 3114. The X-axis driving member 3111 and the X-axis slide rail 3114 are both arranged on the side plate 12. The output end of the X-axis driving member 3111 is connected to the X-axis synchronous belt 3112 by transmission. The X-axis sliding plate 3113 is fixed on the X-axis synchronous belt 3112 and is connected to the X-axis slide rail 3114 by sliding. The movement of the X-axis sliding plate 3113 is realized by the synchronous belt transmission, and the transmission is stable and the cost is low. The X-axis slide rail 3114 is arranged to guide the movement of the X-axis sliding plate 3113. Optionally, in the present embodiment, two X-axis slide rails 3114 are provided, and the two X-axis slide rails 3114 are respectively located on the opposite sides of the X-axis synchronous belt 3112, so as to have a good guiding effect.
[0052] Optionally, in this embodiment, if Figures 2 to 4As shown, the X-axis driving member 3111 is arranged on the side of the side plate 12 away from the sample tube rack 2, and the output end of the X-axis driving member 3111 passes through the side plate 12 and is connected to the X-axis synchronous belt 3112. The X-axis driving member 3111 is arranged on the side of the side plate 12 away from the sample tube rack 2, which increases the operating space of the staff, has a compact structure, avoids interference between the X-axis sliding plate 3113 and the X-axis driving member 3111, and relatively increases the moving stroke of the X-axis sliding plate 3113. Optionally, in other embodiments, the X-axis driving member 3111 is arranged on the side of the side plate 12 close to the sample tube rack 2. The position of the X-axis driving member 3111 is not limited, as long as it can achieve the driving effect, and is not limited to this embodiment.
[0053] Optionally, in this embodiment, if Figure 3 and Figure 4 As shown, the Y-axis moving assembly 312 includes a Y-axis driving member 3121 and a Y-axis output member 3122. The Y-axis driving member 3121 is arranged on the side of the side plate 12 close to the sample tube rack 2. The side plate 12 is provided with a through groove 121 along the X-axis direction. The Y-axis driving member 3121 is fixed on the X-axis sliding plate 3113 through the through groove 121; the output end of the Y-axis driving member 3121 is through the X-axis sliding plate 3113 and is connected to the Y-axis output member 3122 in a transmission manner. The Y-axis driving member 3121 is arranged on the side of the side plate 12 away from the sample tube rack 2, and the Y-axis driving member 3121 is fixed on the Y-axis sliding plate 3124 through the through groove 121, which increases the operating space of the staff and has a compact structure. Optionally, in this embodiment, the Y-axis driving member 3121 is slidably connected to the through groove 121, which has a good guiding effect on the X-axis sliding plate 3113 and increases the support strength of the Y-axis output member 3122.
[0054] Optionally, in this embodiment, if Figure 4 As shown, the Y-axis moving assembly 312 also includes a Y-axis fixed plate 3123, a Y-axis sliding plate 3124 and a Y-axis slide rail 3125 arranged on the Y-axis fixed plate 3123, the Y-axis fixed plate 3123 is fixed to the X-axis sliding plate 3113, the Y-axis output member 3122 is a lead screw, the Y-axis sliding plate 3124 is connected to the lead screw in a transmission manner, and is slidably connected to the Y-axis slide rail 3125. The movement of the Y-axis sliding plate 3124 is achieved through the lead screw transmission, and the transmission accuracy is high. The Y-axis slide rail 3125 is provided to guide the movement of the Y-axis sliding plate 3124. Optionally, in other embodiments, the Y-axis output member 3122 can also be an electric push rod.
[0055] Optionally, in this embodiment, if Figure 4As shown, the Z-axis moving assembly 313 also includes a Z-axis fixed plate 3131, a Z-axis driving member 3132, a Z-axis synchronous pulley 3133, a Z-axis synchronous belt, a Z-axis lead screw 3134 and a Z-axis sliding plate 3135. The Z-axis fixed plate 3131 is fixed on the Y-axis sliding plate 3124. The Z-axis driving member 3132 is arranged on a side of the Z-axis fixed plate 3131 close to the Y-axis fixed plate 3123, and is located between the Y-axis fixed plate 3123 and the Z-axis fixed plate 3131; the output end of the Z-axis driving member 3132 is connected to the Z-axis lead screw 3134 through the Z-axis synchronous pulley 3133 and the Z-axis synchronous belt, the Z-axis sliding plate 3135 is connected to the Z-axis lead screw 3134, and the manipulator assembly 32 is fixed on the Z-axis sliding plate 3135. The Z-axis drive member 3132 is arranged on the side of the Z-axis fixed plate 3131 close to the Y-axis fixed plate 3123, and is located between the Y-axis fixed plate 3123 and the Z-axis fixed plate 3131, with a compact structure and space saving. Through synchronous belt transmission, the transmission is stable and the cost is low. The manipulator assembly 32 is driven to move by the lead screw, and the transmission accuracy is high. Optionally, in other embodiments, the Z-axis drive member 3132 is arranged on the side of the Z-axis fixed plate 3131 away from the Y-axis fixed plate 3123, and the Z-axis drive member 3132 is arranged above the Z-axis fixed plate 3131 and the output end of the Z-axis drive member 3132 is arranged downward. The position of the Z-axis drive member 3132 is not limited, and the driving effect can be achieved, which is not limited to this embodiment. Optionally, in this embodiment, the Z-axis moving assembly 313 also includes a Z-axis slide rail 3136, which is fixed on the Z-axis fixed plate 3131 and is slidably connected to the Z-axis sliding plate 3135. A Z-axis slide rail 3136 is provided to guide the movement of the Z-axis sliding plate 3135 .
[0056] Optionally, in this embodiment, the X-axis drive 3111, the Y-axis drive 3121 and the Z-axis drive 3132 are all motors, which are easy to control and have high reliability. Optionally, the first moving mechanism 31 also includes a photoelectric switch 314, which is used to control the operation and stop of the X-axis moving assembly 311, the Y-axis moving assembly 312 and the Z-axis moving assembly 313, and plays a limiting role. Optionally, in this embodiment, the first moving mechanism 31 also includes an electrical drag chain 6, which is used to organize and protect the wires of the motor.
[0057] Optionally, in this embodiment, the structure of the second moving mechanism 51 is the same as that of the first moving mechanism 31. The structure of the first moving mechanism 31 has good versatility, and the structure of the second moving mechanism 51 is the same as that of the first moving mechanism 31. When installing the second moving mechanism 51, it can be installed according to the installation method of the first moving mechanism 31, thereby improving the installation efficiency. Optionally, in this embodiment, the pipette handle 52 is fixed on the Z-axis sliding plate of the second moving mechanism 51.
[0058] Optionally, in this embodiment, a photoelectric switch 314 is disposed at a position of the side plate 12 close to the penetration groove 121 to limit the position of the Y-axis moving component 312 moving along the X-axis direction; Figure 3 As shown, a photoelectric switch 314 is disposed on the Y-axis fixed plate 3123 to limit the position of the Z-axis moving component 313 moving along the Y-axis direction; Figure 2 As shown, a photoelectric switch 314 is disposed on the Z-axis fixing plate 3131 to limit the position of the manipulator assembly 32 or the pipette handle 52 moving along the Z-axis direction.
[0059] Optionally, in this embodiment, the manipulator assembly 32 includes a first rotating drive member, a second rotating drive member and a manipulator, the first rotating drive member is connected to the Z-axis sliding plate 3135 of the first moving mechanism 31, and the second rotating drive member is arranged at the output end of the first rotating drive member, and the manipulator grasps the sample tube 100 by rotating the second rotating drive member, and the manipulator unscrews or tightens the screw cap 101 of the sample tube 100 by rotating the first rotating drive member. Specifically, as Figure 7 and Figure 8 As shown, the manipulator includes a base 321 and a clamping claw 322. The base 321 is fixed at the output end of the second rotating drive member. Two T-slots 3211 are parallelly and symmetrically arranged at the lower end of the base 321. Two clamping claws 322 are correspondingly arranged in the T-slots 3211, and the clamping claws 322 are slidably connected with the T-slots 3211. The output end of the second rotating drive member passes through the end face of the base 321. A gear is provided at the output end of the second rotating drive member. A rack is provided on one side of the clamping claw 322. The racks provided on the two clamping claws 322 are meshed with the gear. The two clamping claws 322 are driven to move closer or farther from each other by the rotation of the gear, so as to realize the grasping and releasing of the sample tube 100. The structure is simple. Figure 8 In the perspective shown, the output end of the second rotating drive member penetrates the lower end surface of the base 321. Optionally, in this embodiment, the clamping claw 322 includes a T-shaped slider 3221 and a clamping head 3222, the clamping head 3222 is detachably connected to the T-shaped slider 3221, and the rack is arranged on the T-shaped slider 3221, so that the clamping head 3222 can be replaced. Optionally, in this embodiment, one side of the clamping head 3222 is provided with a clamping groove conforming to the outer wall of the sample tube 100, so as to facilitate clamping of the sample tube 100.
[0060] Optionally, in this embodiment, if Figure 1As shown, the pipetting workstation also includes a waste gun tip box 8, which is arranged on the base 11. The waste gun tip box 8 is provided with a feed port 81, which is used as a discard port for the gun tips after use. Optionally, in this embodiment, the bottom of the pipetting gun handle 52 is provided with at least two clamping parts along the circumferential direction, and at least two clamping parts can enter the gun tip through the connection port at the upper end of the gun tip and clamp with the clamping groove of the gun tip; the feed port 81 includes a first opening and a second opening, the second opening is connected to the first opening, the gun tip can enter the waste gun tip box 8 through the first opening, the size of the second opening is smaller than the outer diameter of the connection port of the gun tip, and the pipetting gun handle 52 can be separated from the gun tip through the second opening. When the pipette handle 52 is engaged with the gun tip, the second moving mechanism 51 moves downward along the Z-axis direction, and at least two engaging parts enter the gun tip through the connecting port at the upper end of the gun tip and engage with the engaging groove of the gun tip; when the pipette handle 52 is separated from the gun tip, the second moving mechanism 51 moves downward along the Z-axis direction, so that the gun tip enters the waste gun tip box 8 through the first opening, and then the second moving mechanism 51 moves along the X-axis direction, so that the gun tip moves from below the first opening to below the second opening, and finally, the second moving mechanism 51 moves upward along the Z-axis direction, so that the pipette handle 52 is separated from the gun tip. To facilitate the processing of the gun tips in the waste gun tip box 8, optionally, in this embodiment, the waste gun tip box 8 includes a box body and a box cover, the box cover is provided on the box body, and is detachably connected to the box body, and the feed port 81 is provided on the box cover.
[0061] Optionally, in this embodiment, if Fig. 9 As shown, the anti-drip assembly 53 also includes a driver 532 and a connecting rod 533, the driver 532 is arranged on the second mobile mechanism 51, the connecting rod 533 is connected to the output end of the driver 532, and one end of the waste liquid supporting plate 531 is detachably connected to the connecting rod 533. The waste liquid supporting plate 531 is driven to rotate by the driver 532, which improves the degree of automation. One end of the waste liquid supporting plate 531 is detachably connected to the connecting rod 533, and the waste liquid supporting plate 531 and the connecting rod 533 are disassembled, which is convenient for pouring waste liquid. Optionally, in the present embodiment, the driver 532 is a rotary motor, and the driver 532 is arranged on the side wall of the Z-axis fixed plate of the second mobile mechanism 51 away from the side of the liquid transfer gun handle 52, with a compact structure and space saving. Optionally, in other embodiments, the driver 532 is arranged at the bottom of the Z-axis fixed plate of the second mobile mechanism 51.
[0062] Optionally, in this embodiment, if Figure 1As shown, the frame 1 also includes a housing 13, which includes a first housing 131, a second housing 132 and a third housing 133. The first housing 131 is covered on the periphery of the side plate 12, the second housing 132 is covered on the periphery of the Y-axis moving assembly 312, and the third housing 133 is covered on the periphery of the Z-axis moving assembly 313 for protection. Optionally, in this embodiment, a plurality of support columns are provided at the bottom of the base 11. The support columns are in contact with the ground for easy transportation.
[0063] Optionally, in this embodiment, if Figure 1 As shown, the pipetting workstation also includes a deep well plate 9, which is arranged on the base 11 and is used to accommodate the liquid sucked from the sample tube 100 after the pipette handle 52 is engaged with the gun head. Optionally, in this embodiment, a deep well plate support seat is provided on the base 11, and a groove is provided on the deep well plate support seat, and the deep well plate 9 is inserted into the groove for firm support. Specifically, the deep well plate support seat includes two T-shaped plates, and a receiving groove is provided on one side of the upper end of the T-shaped plate. The two T-shaped plates are opposite and spaced apart on the base 11, and the two ends of the deep well plate 9 are respectively inserted into the two receiving grooves, which has a simple structure and saves costs.
[0064] Optionally, in this embodiment, the waste tip box 8 is an L-shaped structure, and the tip rack 4 and the deep well plate 9 are arranged on the inner side of the waste tip box 8, and the structure is compact. Optionally, in this embodiment, the pipetting workstation further includes a clamping mechanism 10, which is arranged on the base 11 and is used to clamp the sample tube 100. Optionally, in this embodiment, the pipetting workstation further includes a control mechanism for controlling the operation of the sample tube operation unit 3 and the pipetting unit 5.
[0065] Obviously, the above embodiments of the present invention are merely examples for the purpose of clearly illustrating the present invention, and are not intended to limit the implementation methods of the present invention. For those skilled in the art, various obvious changes, readjustments and substitutions can be made without departing from the scope of protection of the present invention. It is not necessary and impossible to list all implementation methods here. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention shall be included in the scope of protection of the claims of the present invention.
Claims
1. A liquid transfer workstation, characterized in that: include: A frame (1) comprising a base (11) and a side plate (12) arranged on one side of the base (11); A sample tube rack (2), arranged on the base (11) and used for placing the sample tube (100); A sample tube operation unit (3), comprising a first moving mechanism (31) and a manipulator assembly (32), wherein the first moving mechanism (31) is arranged on the side plate (12), and the manipulator assembly (32) is arranged at the output end of the first moving mechanism (31), and the manipulator assembly (32) is used to grab the sample tube (100), and after the first moving mechanism (31) moves the sample tube (100) to a position to be clamped and clamps it, the manipulator assembly (32) is used to open the screw cap (101) of the sample tube (100); A gun tip rack (4), arranged on the base (11) and used for placing the gun tip; The pipetting unit (5) comprises a second moving mechanism (51), a pipetting gun handle (52) and an anti-drip assembly (53), wherein the second moving mechanism (51) is arranged on the side plate (12), the pipetting gun handle (52) is arranged at the output end of the second moving mechanism (51), and the pipetting gun handle (52) can be connected to or separated from the gun head; the anti-drip assembly (53) comprises a waste liquid supporting plate (531), one end of the waste liquid supporting plate (531) is rotatably connected to the second moving mechanism (51), and the other end of the waste liquid supporting plate (531) can be located below the gun head after being connected to the pipetting gun handle (52), so as to carry liquid dripping during the pipetting process.
2. The liquid handling workstation according to claim 1, characterized in that: The first moving mechanism (31) comprises an X-axis moving component (311), a Y-axis moving component (312) and a Z-axis moving component (313) which are connected in sequence; the X-axis moving component (311) is arranged on the side plate (12); the Y-axis moving component (312) can move along the X-axis direction on the X-axis moving component (311); the Z-axis moving component (313) moves along the Y-axis direction on the Y-axis moving component (312); the manipulator component (32) is arranged on the Z-axis moving component (313) and can move along the Z-axis direction on the Z-axis moving component (313); the X-axis direction is the length direction of the side plate (12); the X-axis direction, the Y-axis direction and the Z-axis direction are perpendicular to each other.
3. The liquid handling workstation according to claim 2, characterized in that: The X-axis moving assembly (311) comprises an X-axis driving member (3111), an X-axis synchronous belt (3112), an X-axis sliding plate (3113) and an X-axis slide rail (3114); the X-axis driving member (3111) and the X-axis slide rail (3114) are both arranged on the side plate (12); the output end of the X-axis driving member (3111) is transmission-connected to the X-axis synchronous belt (3112); the X-axis sliding plate (3113) is fixed on the X-axis synchronous belt (3112) and is slidingly connected to the X-axis slide rail (3114).
4. The liquid handling workstation according to claim 3, characterized in that: The X-axis driving member (3111) is arranged on a side of the side plate (12) away from the sample tube rack (2), and an output end of the X-axis driving member (3111) passes through the side plate (12) and is drivingly connected to the X-axis synchronous belt (3112).
5. The liquid handling workstation according to claim 3, characterized in that: The Y-axis moving component (312) comprises a Y-axis driving member (3121) and a Y-axis output member (3122); the Y-axis driving member (3121) is arranged on a side of the side plate (12) away from the sample tube rack (2); the side plate (12) is provided with a penetration groove (121) along the X-axis direction; the Y-axis driving member (3121) is fixed to the X-axis sliding plate (3113) through the penetration groove (121); the output end of the Y-axis driving member (3121) penetrates the X-axis sliding plate (3113) and is drivingly connected to the Y-axis output member (3122).
6. The liquid handling workstation according to claim 5, characterized in that: The Y-axis driving member (3121) is slidably connected to the penetration groove (121).
7. The liquid handling workstation according to claim 1, characterized in that: The pipetting workstation further comprises a waste gun tip box (8), wherein the waste gun tip box (8) is arranged on the base (11), and the waste gun tip box (8) is provided with a feed port (81) for serving as a discarding port for used gun tips.
8. The liquid handling workstation according to claim 7, characterized in that: The bottom of the pipette handle (52) is provided with at least two clamping parts along the circumferential direction, and at least two of the clamping parts can enter the gun tip through the connecting port at the upper end of the gun tip and be clamped with the clamping groove of the gun tip; the feed port (81) includes a first opening and a second opening, the second opening is connected to the first opening, the gun tip can enter the waste gun tip box (8) through the first opening, the size of the second opening is smaller than the outer diameter of the connecting port of the gun tip, and the pipette handle (52) can be separated from the gun tip through the second opening.
9. The liquid handling workstation according to claim 1, characterized in that: The anti-drip assembly (53) further comprises a driving member (532) and a connecting rod (533); the driving member (532) is arranged on the second moving mechanism (51); the connecting rod (533) is connected to the output end of the driving member (532); and one end of the waste liquid supporting plate (531) is detachably connected to the connecting rod (533).
10. The liquid handling workstation according to any one of claims 1 to 9, characterized in that: The structure of the second moving mechanism (51) is the same as that of the first moving mechanism (31).