Culture device for research on premature ovarian failure and intestinal flora
By installing pH sensors and temperature sensors in the intestinal microbial culture device, the pH value and temperature of the culture medium are monitored in real time, and the mixing of microbials is promoted through the shaking device, the problem of inability to monitor and manage the culture environment in real time in the prior art is solved. , improves the growth and reproduction success rate of bacterial flora.
Patent Information
- Application Number
- CN202420044151.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-01-09
- Publication Date
- 2025-02-18
- Estimated Expiration
- 2034-01-09
AI Technical Summary
The existing intestinal flora culture device cannot monitor the pH value and temperature in the culture dish in real time, making it difficult to monitor and manage the experimental process, and it is prone to abnormal pH value and temperature, resulting in failure of intestinal flora culture.
A culture device for research on premature ovarian failure and intestinal flora was designed. By installing pH sensors and temperature sensors on the installation parts of the culture device, the pH value and temperature in the culture container can be monitored in real time, and the culture container can be made through the installation mechanism. Shake, promote the mixing of bacterial flora and dispersion of bacterial moss, and improve the growth and reproduction environment of bacterial flora.
Real-time monitoring and management of the pH value and temperature of the culture medium is achieved, abnormal situations are avoided, the success rate of intestinal microbial culture is improved, and the uniform growth and reproduction of microbial species is promoted.
Smart Images

Figure CN222499149U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of flora culture equipment, in particular to a culture device for studying premature ovarian failure and intestinal flora. Background Art
[0002] Premature ovarian failure refers to the phenomenon of ovarian dysfunction in women before the age of 40, manifested by decreased estrogen levels, abnormal menstruation and other symptoms. Studies in recent years have shown that there is a close connection between intestinal flora and the occurrence and development of premature ovarian failure. The human gastrointestinal tract is home to a wide variety of microorganisms, which are called intestinal flora. The intestinal flora is combined in a certain proportion, and the bacteria restrict and depend on each other, forming an ecological balance in quality and quantity. The intestinal flora responds to the nutrients consumed by the host through various hormones, and also responds to the state of the host.
[0003] Existing intestinal flora culture devices are not convenient for real-time monitoring of the pH value in the culture dish, and it is not convenient for researchers to monitor and manage the experimental process to avoid abnormal pH and temperature, which may lead to failure of intestinal flora culture. In addition, the culture dish cannot be moved, which affects the growth and reproduction of the flora. Utility Model Content
[0004] The utility model provides a culture device for studying premature ovarian failure and intestinal flora. By installing a pH sensor and a temperature sensor on a component, the pH value of a culture solution in a culture container and the temperature in the culture container can be monitored, so that researchers can monitor and manage the experimental process conveniently, and avoid abnormal pH value and temperature, which may lead to failure of intestinal flora culture. The installation mechanism is used to place the culture container and shake the culture container so that the flora in the culture container is evenly mixed and the bacterial moss is dispersed, which is conducive to better growth and reproduction of the flora in the culture container.
[0005] To achieve the above objectives, the utility model is implemented through the following technical solutions: a culture device for studying premature ovarian failure and intestinal flora, comprising:
[0006] Incubator;
[0007] A mounting mechanism is arranged in the incubator, the mounting mechanism comprises a moving part, a moving plate and a plurality of mounting racks, the moving part is arranged in the incubator, the moving plate is arranged on the moving part, and each mounting rack is fixedly arranged at an equal distance on the top of the outer wall of the moving plate in the horizontal direction;
[0008] A heating device is installed at the bottom of the inner wall of the incubator;
[0009] a culture container mounted on an inner wall of the mounting frame; and
[0010] The monitoring mechanism is arranged in the incubator, and the monitoring mechanism comprises a mounting component, a plurality of pH sensors and a plurality of temperature sensors. The mounting component is arranged in the incubator, each of the pH sensors is arranged on the mounting component, and each of the temperature sensors is arranged on the mounting component.
[0011] Furthermore, the moving component includes a moving cylinder and four groups of elastic components. The moving cylinder is installed on one side of the outer wall of the incubator, and each group of elastic components is arranged on both sides of the outer wall of the moving plate.
[0012] Furthermore, each group of the elastic components includes a moving groove, a moving block and two springs. The moving groove is opened on one side of the outer wall of the incubator, the moving block is slidably embedded in the inner wall of the moving groove, and the moving block is fixedly arranged at the bottom of the outer wall of the moving plate, and each of the springs is fixedly arranged between the moving groove and the moving block.
[0013] Furthermore, one of the moving blocks is fixedly arranged at the output end of the moving cylinder, and the moving plate is located above the heating device.
[0014] Furthermore, the mounting component includes a telescopic cylinder and a mounting plate, the telescopic cylinder is mounted on one side of the inner wall of the incubator, and the mounting plate is fixedly arranged on the output end of the telescopic cylinder.
[0015] Furthermore, each of the pH sensors is installed at an equal distance on the top of the outer wall of the mounting plate, and each of the temperature sensors is installed at an equal distance on the top of the outer wall of the mounting plate.
[0016] The utility model provides a culture device for the study of premature ovarian failure and intestinal flora.
[0017] Beneficial effects:
[0018] (1) The culture device for the study of premature ovarian failure and intestinal flora can monitor the pH value of the culture fluid in the culture container and the temperature in the culture container by installing a pH sensor and a temperature sensor on the components, so as to facilitate researchers to monitor and manage the experimental process and avoid abnormal pH value and temperature, which may lead to failure of intestinal flora culture.
[0019] (2) The culture device for the study of premature ovarian failure and intestinal flora is used to place a culture container through an installation mechanism, and shake the culture container to mix the flora in the culture container evenly and disperse the bacterial moss, which is conducive to better growth and reproduction of the flora in the culture container. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 It is a three-dimensional diagram of the utility model;
[0021] Figure 2 It is a cross-sectional view of the utility model;
[0022] Figure 3 It is a partial cross-sectional view of the utility model.
[0023] In the figure: 1. incubator; 2. mounting mechanism; 201. moving plate; 202. mounting frame; 203. moving cylinder; 204. moving slot; 205. moving block; 206. spring; 3. heating device; 4. culture container; 5. monitoring mechanism; 501. pH sensor; 502. temperature sensor; 503. telescopic cylinder; 504. mounting plate. DETAILED DESCRIPTION
[0024] The following will clearly and completely describe the technical solutions in the embodiments of the utility model in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0025] See also Figure 1-3 The utility model provides a technical solution: a culture device for studying premature ovarian failure and intestinal flora, comprising:
[0026] Incubator 1;
[0027] The mounting mechanism 2 is arranged in the incubator 1, and the mounting mechanism 2 comprises a moving part, a moving plate 201 and a plurality of mounting racks 202. The moving part is arranged in the incubator 1, and the moving plate 201 is arranged on the moving part. Each mounting rack 202 is fixedly arranged at the top of the outer wall of the moving plate 201 at equal intervals in the horizontal direction.
[0028] A heating device 3 is installed at the bottom of the inner wall of the incubator 1;
[0029] A culture container 4 is mounted on the inner wall of the mounting frame 202; and
[0030] The monitoring mechanism 5 is arranged in the incubator 1. The monitoring mechanism 5 includes a mounting component, multiple pH sensors 501 and multiple temperature sensors 502. The mounting component is arranged in the incubator 1. Each pH sensor 501 is arranged on the mounting component, and each temperature sensor 502 is arranged on the mounting component.
[0031] In this embodiment: the incubator 1 is provided with a gas control device, which can introduce an appropriate amount of oxygen and carbon dioxide into the incubator 1 according to the experimental needs, so as to simulate the gas environment in the human intestine. The incubator 1 is provided with an observation window on the cover, so as to observe the intestinal flora in the culture container 4. The mounting mechanism 2 is used to place the culture container 4 and shake the culture container 4 so that the flora in the culture container 4 is evenly mixed and the bacterial moss is dispersed, which is conducive to the better growth and reproduction of the flora in the culture container 4. The moving plate 201 is driven by the moving component to move, so that the culture container 4 on the mounting frame 202 can be moved, and the culture liquid in the culture container 4 can be shaken to mix the flora evenly. The heating device 3 is used to adjust the temperature in the incubator 1 to simulate the normal body temperature of the human body. The container 4 is made of transparent glass. The pH value of the culture solution in the culture container 4 and the temperature in the culture container 4 can be monitored through the pH sensor 501 and the temperature sensor 502, which is convenient for researchers to monitor and manage the experimental process and avoid abnormal pH value and temperature, which may lead to failure of intestinal flora culture. The pH value of the culture solution can be monitored through the pH sensor 501, which can ensure that the culture environment is maintained within an appropriate pH range, which is conducive to the normal growth of the flora. The installation components are used to install and place the pH sensor 501 and the temperature sensor 502, and drive the pH sensor 501 and the temperature sensor 502 into the culture container 4. The number of pH sensors 501 and temperature sensors 502 can be set according to actual needs.
[0032] Specifically, the moving component includes a moving cylinder 203 and four groups of elastic components. The moving cylinder 203 is installed on one side of the outer wall of the incubator 1 , and each group of elastic components is arranged on both sides of the outer wall of the moving plate 201 .
[0033] In this embodiment, the moving cylinder 203 is used to drive the moving plate 201 to move, and each group of elastic components guides the movement of the moving plate 201.
[0034] Specifically, each group of elastic components includes a moving groove 204, a moving block 205 and two springs 206. The moving groove 204 is opened on one side of the outer wall of the incubator 1. The moving block 205 is slidably embedded in the inner wall of the moving groove 204, and the moving block 205 is fixedly set at the bottom of the outer wall of the moving plate 201. Each spring 206 is fixedly set between the moving groove 204 and the moving block 205.
[0035] In this embodiment, the moving block 205 moves in the moving groove 204 to guide the movement of the moving plate 201 , and the spring 206 acts as a buffer to increase the stability of the moving block 205 .
[0036] Specifically, one of the moving blocks 205 is fixedly disposed at the output end of the moving cylinder 203 , and the moving plate 201 is located above the heating device 3 .
[0037] In this embodiment: by driving one of the moving blocks 205 to move in the moving groove 204 through the moving cylinder 203, the moving plate 201 can be driven to move, thereby moving the culture container 4 on the mounting frame 202, and the culture liquid in the culture container 4 can be shaken to mix the bacterial flora evenly.
[0038] Specifically, the mounting component includes a telescopic cylinder 503 and a mounting plate 504 . The telescopic cylinder 503 is mounted on one side of the inner wall of the incubator 1 , and the mounting plate 504 is fixedly disposed on the output end of the telescopic cylinder 503 .
[0039] In this embodiment: the mounting plate 504 is driven to rise and fall by the telescopic cylinder 503, which can drive the pH sensor 501 and the temperature sensor 502 to enter the culture container 4. The power of the telescopic cylinder 503, the movable cylinder 203, the pH sensor 501, the temperature sensor 502 and the heating device 3 comes from an external power supply, which should be electrically connected to the external power supply. The internal circuit principle structure belongs to the common knowledge of technicians in this field and will not be introduced in detail here. The model can be selected according to actual usage.
[0040] Specifically, each pH sensor 501 is installed at an equal distance on the top of the outer wall of the mounting plate 504 , and each temperature sensor 502 is installed at an equal distance on the top of the outer wall of the mounting plate 504 .
[0041] In this embodiment, a temperature sensor 502 is provided next to each pH sensor 501 , and both the pH sensor 501 and the temperature sensor 502 are located above each mounting bracket 202 .
[0042] When in use, first place the culture container 4 into the mounting frame 202, then start the moving cylinder 203, drive one of the moving blocks 205 to move in the moving groove 204, so that the moving plate 201 drives the culture container 4 to move, which can make the culture liquid in the culture container 4 shake and make the bacterial flora evenly mixed, and then start the telescopic cylinder 503 to drive the mounting plate 504 to rise and fall, which can drive the pH sensor 501 and the temperature sensor 502 to enter the culture container 4 to monitor the pH value of the culture liquid, which can ensure that the culture environment is maintained within the appropriate pH range, and monitor the temperature in the culture container 4, so as to facilitate researchers to monitor and manage the experimental process and avoid abnormal pH and temperature, which may lead to failure of intestinal flora culture.
[0043] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.
Claims
1. A culture device for the study of premature ovarian failure and intestinal flora, characterized in that: include: Incubator (1); A mounting mechanism (2) is arranged in the incubator (1), the mounting mechanism (2) comprising a moving component, a moving plate (201) and a plurality of mounting racks (202), the moving component is arranged in the incubator (1), the moving plate (201) is arranged on the moving component, and each mounting rack (202) is fixedly arranged at equal distances in a horizontal direction on the top of the outer wall of the moving plate (201); A heating device (3) is installed at the bottom of the inner wall of the incubator (1); A culture container (4) mounted on the inner wall of the mounting frame (202); and A monitoring mechanism (5) is arranged in an incubator (1), the monitoring mechanism (5) comprising a mounting component, a plurality of pH sensors (501) and a plurality of temperature sensors (502); the mounting component is arranged in the incubator (1), each of the pH sensors (501) is arranged on the mounting component, and each of the temperature sensors (502) is arranged on the mounting component.
2. A culture device for studying premature ovarian failure and intestinal flora according to claim 1, characterized in that: The moving component comprises a moving cylinder (203) and four groups of elastic components. The moving cylinder (203) is installed on one side of the outer wall of the incubator (1), and each group of elastic components is arranged on both sides of the outer wall of the moving plate (201).
3. A culture device for studying premature ovarian failure and intestinal flora according to claim 2, characterized in that: Each group of the elastic components comprises a moving groove (204), a moving block (205) and two springs (206); the moving groove (204) is opened on one side of the outer wall of the incubator (1); the moving block (205) is slidably embedded in the inner wall of the moving groove (204); the moving block (205) is fixedly arranged at the bottom of the outer wall of the moving plate (201); and each of the springs (206) is fixedly arranged between the moving groove (204) and the moving block (205).
4. A culture device for studying premature ovarian failure and intestinal flora according to claim 3, characterized in that: One of the moving blocks (205) is fixedly arranged at the output end of the moving cylinder (203), and the moving plate (201) is located above the heating device (3).
5. A culture device for studying premature ovarian failure and intestinal flora according to claim 4, characterized in that: The mounting component comprises a telescopic cylinder (503) and a mounting plate (504); the telescopic cylinder (503) is mounted on one side of the inner wall of the incubator (1); and the mounting plate (504) is fixedly arranged on the output end of the telescopic cylinder (503).
6. A culture device for studying premature ovarian failure and intestinal flora according to claim 5, characterized in that: Each of the pH sensors (501) is installed at an equal distance on the top of the outer wall of the mounting plate (504), and each of the temperature sensors (502) is installed at an equal distance on the top of the outer wall of the mounting plate (504).