Microfluidic detector
By forming a cooling chamber on the support of the microfluidic detector, the problem of overheating of the eccentric motor is solved, and efficient heat dissipation and miniaturization are achieved.
Patent Information
- Application Number
- CN202420490741.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-13
- Publication Date
- 2025-02-18
- Estimated Expiration
- 2034-03-13
AI Technical Summary
In existing microfluidic detectors, eccentric motors are prone to overheating after long use, resulting in unstable vibration frequency and affecting experimental accuracy. The existing heat dissipation structure occupies a large space and is difficult to miniaturize.
A heat dissipation structure with a small space is designed. By hinging the bracket on the bracket, a cooling chamber is formed, and an inlet and outlet are opened on the bracket to increase the heat exchange area and heat dissipation efficiency.
It realizes efficient heat dissipation, reduces the space occupied by the heat dissipation structure, and improves the accuracy and miniaturization capabilities of the microfluidic detector.
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Figure CN222506326U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of microfluidics, in particular to a microfluidics detector. Background Art
[0002] At present, it is common to use the immunomagnetic bead method to detect substances to be tested in microfluidic chips. The test objects include proteins, electrolytes, microorganisms, etc. However, due to the small size of the reaction chamber of the microfluidic chip, the contact efficiency between the immunomagnetic beads and the substances to be tested is low in a static state and the detection time is long. Generally, an eccentric motor is used to vibrate the reaction chamber to increase the number of collisions between the substances to be tested and the immunomagnetic beads. However, severe overheating of the eccentric motor after long-term use can cause unstable vibration frequency, which greatly affects the accuracy of the experiment.
[0003] In response to the above problems, the prior art, such as a Chinese utility model patent with patent number CN202310862214.9 (publication number CN116943758A) entitled "A Microfluidic Chip and Detector", discloses a fan for dissipating heat from a motor. The fan is arranged on a motor bracket. The fan in this patent takes away part of the heat from the surface of the motor casing through thermal convection, so that the motor does not overheat. However, the components used in microfluidic instruments are generally small in size. If the fan wants to quickly take away the heat from the surface of the motor casing, its volume must be significantly larger than the volume of the motor, which is not conducive to the miniaturization of the functional modules of the microfluidic instrument. Summary of the invention
[0004] The technical problem to be solved by the utility model is to provide a microfluidic detector with a heat dissipation structure that occupies a small space in view of the above-mentioned existing technical status.
[0005] The technical solution adopted by the utility model to solve the above technical problems is: the microfluidic detector includes a shell and a support arranged in the shell, the upper surface of the support is provided with a microfluidic chip, and the support is provided with a vibration element acting on the microfluidic chip, characterized in that: a bracket is hinged on the support, a mounting seat for mounting the vibration element is provided in the center of the bracket, the bracket surrounds the wall of the mounting seat, the gap between the wall of the mounting seat and the bracket forms a cooling cavity, and an inlet and an outlet connected to the cooling cavity fluid are opened on the bracket.
[0006] In order to further reduce the volume of the bracket, from the perspective of simple structure, preferably, the bracket is tubular, including an inner ring wall surface and an outer ring wall surface arranged at intervals, and a first wall surface connecting the inner ring wall surface and the outer ring wall surface, the inner ring wall surface encloses the mounting seat, and the gap between the inner ring wall surface and the outer ring wall surface constitutes the cooling cavity. The inner ring wall surface has a dual-purpose function, and the sandwich structure formed by the inner ring wall surface and the outer ring wall surface not only constitutes the cooling cavity, but also the inner ring wall surface encloses the mounting seat, so that the user does not need to separately set the mounting seat in the bracket, further reducing the installation space of the overall heat dissipation structure.
[0007] In order to achieve the connection between the vibration element and the bracket, the bracket further includes a connecting piece at least partially embedded in the ends of the inner ring wall and the outer ring wall, and the vibration element is inserted into the mounting seat by cooperating with the connecting piece.
[0008] In order to ensure the sealing of the cooling chamber when in use, preferably, the connecting piece is sealed with the cooling chamber, and the tail of the vibration element is radially outwardly protruded with an annular convex ring, and the annular convex ring is connected to the connecting piece. The sealing relationship between the connecting piece and the cooling chamber prevents the cooling chamber from leaking water from the tail end of the vibration element after installation, and the annular convex ring also facilitates the user to install the vibration element, and the annular convex ring also plays a corresponding anti-leakage role.
[0009] In order to further enhance the sealing performance of the cooling cavity, preferably, the inner side of the annular convex ring is provided with an annular stopper plugged with the connector, and the outer diameter of the stopper is larger than the inner diameter of the outer ring wall and the inner diameter of the stopper is smaller than the outer diameter of the inner ring wall. The setting of the stopper has the following functions: first, it ensures that the connector is only embedded at the ends of the inner ring wall and the outer ring wall, and the position setting of the connector itself is not too deep relative to the inner ring, thereby reducing the volume of the cooling cavity and increasing the heat dissipation area to the greatest extent; second, it prevents accidental leakage at the matching gap of the connector, and has the advantage of "one thing for two purposes".
[0010] In order to facilitate the user to adjust the vibration intensity of the vibration element on the reaction chamber, preferably, a hinge assembly is connected between the bracket and the support, and the hinge assembly includes:
[0011] A connecting hoop, wherein the hoop body of the connecting hoop partially surrounds the outer ring wall surface and extends downward at both ends of the hoop body to form a first connecting leg and a second connecting leg respectively, a connecting rib is provided between the first connecting leg and the second connecting leg, and the lower ends of the first connecting leg and the second connecting leg are provided on the sleeve;
[0012] A rotating shaft, passing through the sleeve;
[0013] The hinged frame is arranged on one side of the support, and the hinged frame is rotatably connected to the connecting hoop through a rotating shaft. The user can control the distance between the vibration head of the vibration element and the reaction chamber through the rotation angle of the rotating shaft.
[0014] In order to ensure that the reaction and detection processes of the microfluidic detector do not interfere with each other, preferably, the microfluidic chip has a reaction chamber and a detection chamber, and the vibration element acts on the reaction chamber. The separate arrangement of the reaction chamber and the detection chamber prevents the positions of the detection module and the bracket from interfering with each other, which is convenient for installation; the arrangement of the vibration element acting on the reaction chamber concentrates the action area of the vibration element, so that the magnetic beads in the reaction chamber are evenly mixed.
[0015] In order to reduce the volume of the microfluidic detector, preferably, the microfluidic detector further includes a detection module for detecting the optical signal in the detection chamber, the detection module is connected to the support, and the detection module includes:
[0016] A detection cabinet, wherein the detection cabinet is provided with a detection slot on a side facing the microfluidic chip, the microfluidic chip is partially placed on the lower slot wall of the detection slot, and the detection slot covers the detection chamber;
[0017] An emitting sensor, wherein a first mounting hole is formed on the lower wall of the detection slot, the emitting sensor is disposed in the first mounting hole, the emitting end of the emitting sensor is disposed upward and directly facing the detection chamber, the emitting sensor serves as a light source and can adjust the wavelength of the light source;
[0018] The receiving sensor is provided with a second mounting hole on the upper wall of the detection slot, and the receiving sensor is arranged in the second mounting hole. The sensing end of the receiving sensor is arranged downward and directly opposite to the detection chamber, and is used to receive the light signal emitted by the transmitting sensor. The transmitting sensor and the receiving sensor are both integrated into the detection cabinet, and the microfluidic chip is partially placed in the detection slot, which makes full use of the space of the detection slot.
[0019] In order to facilitate the user to control the movement state of the magnetic beads, preferably, the support forms a mounting cavity below the microfluidic chip, and a magnetic field generating module for controlling the movement state of the magnetic beads in the reaction chamber is provided at the bottom of the mounting cavity. The user determines whether the magnetic beads are magnetically attracted by controlling whether the magnetic field generating module generates a magnetic field.
[0020] In order to increase the detection range of the detection module for the optical signal, preferably, a signal box installation groove is recessed on one side of the support, and a signal processing box is arranged in the signal box installation groove, and the signal processing box is connected to the transmitting sensor and the receiving sensor, and is used to control the wavelength of the light source of the transmitting sensor and receive and process the optical signal received by the receiving sensor. The wavelength of the light source of the transmitting sensor is adjusted to adapt to the maximum absorption wavelength of different reaction products.
[0021] In order to facilitate the user to use the microfluidic detector, preferably, a mounting plate is connected to the outward side of the signal box mounting slot, and a display screen connected to the signal processing box is provided on the mounting plate, and the display screen is used to display the optical information of the receiving sensor and the wavelength value of the receiving sensor input by touch screen. The direct feedback of the optical information and the touch screen operation facilitate the user to understand and adjust the results and parameters of the detection module.
[0022] Compared with the prior art, the advantages of the utility model are:
[0023] 1. The cooling cavity of the microfluidic detector is formed in the gap between the wall of the mounting seat and the bracket. This design not only increases the heat exchange area with the vibration element, but also improves the heat dissipation efficiency;
[0024] 2. The arrangement of the cooling chamber at the gap does not require the installation of an additional heat dissipation module, so that the overall space occupied by the vibration module is small, and it has the advantages of high heat dissipation efficiency and small space occupation. BRIEF DESCRIPTION OF THE DRAWINGS
[0025] Figure 1 It is a schematic diagram of the structure of an embodiment of the utility model;
[0026] Figure 2 This is a schematic diagram of a partial structure of an embodiment of the utility model after removing the shell;
[0027] Figure 3 A schematic diagram of the structure of a vibration element and a bracket according to an embodiment of the utility model;
[0028] Figure 4 A longitudinal cross-sectional view of a vibration element and a bracket according to an embodiment of the utility model;
[0029] Figure 5 A longitudinal cross-sectional view of the vibration element and the bracket of the embodiment of the utility model at another angle;
[0030] Figure 6 It is a structural explosion diagram of the vibration element and the bracket of the embodiment of the utility model;
[0031] Figure 7 It is a schematic diagram of the structure of the bracket and the hinge assembly of the embodiment of the utility model;
[0032] Figure 8 It is a structural exploded diagram of the hinge assembly of an embodiment of the utility model;
[0033] Fig. 9 This is a schematic diagram of the structure of the microfluidic chip of an embodiment of the utility model;
[0034] Fig.10 for Figure 2 A longitudinal section of
[0035] Fig.11 This is a schematic diagram of the structure of the detection module of an embodiment of the utility model;
[0036] Fig.12 A longitudinal cross-sectional view of a detection module according to an embodiment of the present utility model;
[0037] Fig.13 for Figure 2 A schematic diagram of the structure from another angle. DETAILED DESCRIPTION
[0038] The present invention will be described in further detail below in conjunction with the accompanying drawings.
[0039] like Figures 1 to 13 The figure shows the best embodiment of the utility model. The microfluidic detector is mainly used for rapid detection of biological samples. When a vibrating element (such as a vibrating element) is used in the microfluidic detector to accelerate biochemical reactions, a module for dissipating heat from the vibrating element must be provided in the microfluidic detector. However, due to the high density of integrated components in the microfluidic instrument, the volume of the heat dissipation module cannot be too large to save space for installing modules with other functions. Therefore, it would be beneficial to provide a microfluidic detector with a motor heat dissipation module that occupies a small space. The following will expand the structural description of the microfluidic detector:
[0040] See also Figures 1 to 6 The microfluidic detector includes a housing 1 and a support 2 disposed in the housing 1. A microfluidic chip 3 is disposed on the upper surface of the support 2. A vibration element 4 acting on the microfluidic chip 3 is disposed on the support 2. A bracket 5 is hinged on the support 2. A mounting seat 6 for mounting the vibration element 4 is disposed in the center of the bracket 5. The bracket 5 surrounds the wall of the mounting seat 6. A cooling cavity 50 is formed between the wall of the mounting seat 6 and the bracket 5. An inlet 501 and an outlet 502 in fluid communication with the cooling cavity 50 are provided on the bracket 5. The vibration element 4 may be a vibration motor.
[0041] See also Figure 4The bracket 5 of this embodiment is tubular, including an inner ring wall 51 and an outer ring wall 52 arranged at intervals, and a first wall 53 connecting the inner ring wall 51 and the outer ring wall 52; the inner ring wall 51 surrounds the mounting seat 6, and the gap between the inner ring wall 51 and the outer ring wall 52 constitutes a cooling cavity 50. The inner ring wall 51 has a dual-purpose function. The sandwich structure formed by the inner ring wall 51 and the outer ring wall 52 not only constitutes the cooling cavity 50, but also surrounds the mounting seat 6, so that the user does not need to separately set the mounting seat 6 in the bracket 5, further reducing the installation space of the entire heat dissipation structure. The bracket 5 also includes a connector 54 at least partially embedded in the ends of the inner ring wall 51 and the outer ring wall 52, and the vibration element 4 is inserted into the mounting seat 6 by cooperating with the connector 54. The connector 54 is sealed with the cooling cavity 50, and the tail of the vibration element 4 is radially outwardly protruded with an annular convex ring 41, which is connected to the connector 54. The sealing relationship between the connector 54 and the cooling cavity 50 prevents the cooling cavity 50 from leaking from the tail end after the vibration element 4 is installed, plays a corresponding anti-leakage role, and ensures the sealing of the cooling cavity 50 when in use. The annular convex ring 41 also facilitates the user to install the vibration element 4, wherein the connector 54 can be an elastic rubber sealing plug. An annular stopper 55 is provided on the inner side of the annular convex ring 41, which is plugged with the connector 54 and is annular. The outer diameter of the stopper 55 is larger than the inner diameter of the outer ring wall 52, and the inner diameter of the stopper 55 is smaller than the outer diameter of the inner ring wall 51. The setting of the stopper 55 has the following functions: first, it ensures that the connector 54 is only embedded at the ends of the inner ring wall 51 and the outer ring wall 52, and the position setting of the connector 54 itself is not too deep relative to the inner ring wall 51, thereby reducing the volume of the cooling cavity 50 and increasing the heat dissipation area to the greatest extent; second, it prevents accidental leakage at the matching gap between the connector 54 and the inner ring wall 51, has the advantage of "one thing for two purposes", and further enhances the sealing of the cooling cavity 50. The annular convex ring 41 is provided with a screw hole, and the annular convex ring 41 is threadedly connected to the stopper 55, which is convenient for users to disassemble the vibration element 4 separately.
[0042] See also Figures 7 and 8, a hinge assembly 56 is connected between the bracket 5 and the support 2, and the hinge assembly 56 includes a connecting hoop 561, a rotating shaft 562 and a hinge frame 563, wherein the hoop body 5611 of the connecting hoop 561 partially surrounds the outer ring wall 52 and extends downward at both ends of the hoop body 5611 to form a first connecting leg 5612 and a second connecting leg 5613, respectively, a connecting rib 5614 is provided between the first connecting leg 5612 and the second connecting leg 5613, and the lower ends of the first connecting leg 5612 and the second connecting leg 5613 are arranged on the sleeve 5615; the rotating shaft 562 is passed through the sleeve 5615; the hinge frame 563 is arranged on one side of the support 2, and the hinge frame 563 and the connecting hoop 561 are rotatably connected through the rotating shaft 562. The user can control the distance between the vibration head of the vibration element 4 and the reaction chamber 31 through the rotation angle of the rotating shaft 562, which is convenient for the user to adjust the vibration intensity of the vibration element 4 on the reaction chamber 31.
[0043] In addition, see Fig. 9 , the microfluidic chip 3 has a reaction chamber 31 and a detection chamber 32, and the vibration element 4 acts on the reaction chamber 31. The microfluidic chip 3 also has a liquid inlet for adding samples and a liquid outlet for discharging waste liquid. The separate arrangement of the reaction chamber 31 and the detection chamber 32 prevents the positions of the detection module 7 and the bracket 5 from interfering with each other, which is convenient for installation; the arrangement of the vibration element 4 acting on the reaction chamber 31 concentrates the action area of the vibration element 4, so that the magnetic beads in the reaction chamber 31 are evenly mixed, so that the reaction and detection processes of the microfluidic detector do not interfere with each other. The microfluidic detector also includes a detection module 7 for detecting optical signals in the detection chamber 32, the detection module 7 is connected to the support 2, and the detection module 7 includes a detection cabinet 71, a transmitting sensor 72 and a receiving sensor 73. The detection cabinet 71 is recessed with a detection groove 711 on the side facing the microfluidic chip 3, and the microfluidic chip 3 is partially placed on the lower groove wall of the detection groove 711, and the detection groove 711 covers the detection chamber 32; a first mounting hole 712 is penetrated on the lower groove wall of the detection groove 711, and the transmitting sensor 72 is arranged in the first mounting hole 712, and the transmitting end of the transmitting sensor 72 is arranged upward and facing the detection chamber 32, and the transmitting sensor 72 serves as a light source and can adjust the wavelength of the light source; a second mounting hole 713 is penetrated on the upper groove wall of the detection groove 711, and the receiving sensor 73 is arranged in the second mounting hole 713, and the sensing end of the receiving sensor 73 is arranged downward and facing the detection chamber 32, for receiving the light signal emitted by the transmitting sensor 72. The bottom of the detection slot 711 is provided with a discharge hole for passing the waste liquid discharge pipe. The transmitting sensor 72 and the receiving sensor 73 are integrated in the detection cabinet 71 and the microfluidic chip 3 is partially placed in the detection slot 711. This arrangement fully utilizes the space of the detection slot 711 and reduces the volume of the microfluidic detector. For details, please refer to 10 to 12.
[0044] Finally, see Fig.13The support 2 is formed with an installation cavity 21 below the microfluidic chip 3. The bottom of the installation cavity 21 is provided with a magnetic field generating module 8 for controlling the movement state of the magnetic beads in the reaction chamber 31. The user determines whether the magnetic beads in the reaction chamber 31 are magnetically attracted by controlling whether the magnetic field generating module 8 generates a magnetic field, which facilitates the user to control the movement state of the magnetic beads. Among them, a signal box installation groove 22 is recessed on one side of the support 2, and a signal processing box 9 is provided in the signal box installation groove 22. The signal processing box 9 is connected to the transmitting sensor 72 and the receiving sensor 73, and is used to control the wavelength of the light source of the transmitting sensor 72 and receive and process the light signal received by the receiving sensor 73. At the same time, the signal processing box 9 can also control the opening and closing of the vibration element 4 and the opening and closing of the magnetic field generating module 8 at the same time. The rotating shaft 562 can also be driven by a rotating motor, and the rotating motor is controlled by the signal processing box 9 to realize automatic adjustment of the rotation angle of the rotating shaft 562. By adjusting the wavelength of the light source of the transmitting sensor 72 to adapt to the maximum absorption wavelength of different reaction products, the detection range of the detection module 7 for the light signal is increased. The mounting plate 23 is connected to the outward side of the signal box mounting groove 22, and a display screen 10 connected to the signal processing box 9 is provided on the mounting plate 23, and the display screen 10 is used to display the optical information of the receiving sensor 73 and the wavelength value of the receiving sensor 73 input by touch screen. The direct feedback of the optical information and the touch screen operation are convenient for users to understand and adjust the results and parameters of the detection module, and are convenient for users to use the microfluidic detector. The user can also set a sampling module in the housing 1, and the sampling module includes a sampling chamber and a sampling pump. The sampling chamber is connected to the microfluidic chip 3 by pipeline, and the sampling pump is connected to the signal processing box 9 control. The reaction liquid is added to the sampling chamber in advance, and the sampling pump is turned on through the signal processing box 9 when sampling is required.
[0045] The use process of the present microfluidic detector is as follows: the user first adds an antimagnetic bead and a sample solution to be detected into the reaction chamber 31 through the liquid inlet. After the antimagnetic bead and the sample solution to be detected have completely entered the reaction chamber 31, the signal processing box 9 controls the rotating motor through a pre-set program to drive the rotating shaft 562 to rotate counterclockwise so that the vibration head of the vibration element 4 is close to the reaction chamber 31. After the position of the vibration head is adjusted to be directly above the reaction chamber 31, the vibration element 4 is started to start incubation; after 0.5 to 1 minute of incubation, the vibration element 4 is turned off, the rotating motor controls the rotating shaft 562 to rotate clockwise to the original state, and then the magnetic field generating module 8 is turned on to incubate the antimagnetic bead that has been incubated. Perform magnetic separation, discharge the separated waste liquid in the reaction chamber 31 from the liquid outlet, add enzyme-labeled secondary antibody reagent into the reaction chamber 31, turn off the magnetic field generating module 8, and rotate the motor to drive the rotating shaft 562 to rotate counterclockwise so that the vibration head of the vibration element 4 is close to the reaction chamber 31, start the vibration element 4 to start the secondary incubation, turn off the vibration element 4 after the secondary incubation, turn on the magnetic field generating module 8 to magnetically separate the immunomagnetic beads after the secondary incubation, then empty it, add the color developing solution and the stop solution in turn to obtain the liquid to be detected, push the liquid to be detected into the detection chamber 32, turn on the detection module 7 to detect and read the data, and rinse and empty the microfluidic chip 3 after the experiment is completed.
Claims
1. A microfluidic detector, comprising a housing (1) and a support (2) arranged in the housing (1), a microfluidic chip (3) being arranged on the upper surface of the support (2), and a vibrating element (4) acting on the microfluidic chip (3) being arranged on the support (2), characterized in that: A bracket (5) is hingedly connected to the support (2), a mounting seat (6) for mounting a vibration element (4) is provided in the center of the bracket (5), the bracket (5) surrounds the wall of the mounting seat (6), a cooling cavity (50) is formed in the gap between the wall of the mounting seat (6) and the bracket (5), and an inlet (501) and an outlet (502) which are in fluid communication with the cooling cavity (50) are provided on the bracket (5).
2. The microfluidic detector according to claim 1, characterized in that: The bracket (5) is tubular and includes an inner ring wall (51) and an outer ring wall (52) that are spaced apart and a first wall (53) connecting the inner ring wall (51) and the outer ring wall (52); the inner ring wall (51) surrounds the mounting seat (6); and the gap between the inner ring wall (51) and the outer ring wall (52) constitutes the cooling cavity (50).
3. The microfluidic detector according to claim 2, characterized in that: The bracket (5) also includes a connecting piece (54) at least partially embedded in the ends of the inner ring wall surface (51) and the outer ring wall surface (52), and the vibration element (4) is inserted into the mounting seat (6) by cooperating with the connecting piece (54).
4. The microfluidic detector according to claim 3, characterized in that: The connecting piece (54) is sealed with the cooling cavity (50); the tail of the vibration element (4) is provided with an annular convex ring (41) protruding radially outward; and the annular convex ring (41) is connected to the connecting piece (54).
5. The microfluidic detector according to claim 4, characterized in that: An annular stopper (55) is provided on the inner side of the annular protrusion (41) and is plugged into the connecting member (54). The outer diameter of the stopper (55) is larger than the inner diameter of the outer ring wall (52), and the inner diameter of the stopper (55) is smaller than the outer diameter of the inner ring wall (51).
6. The microfluidic detector according to claim 2, characterized in that: A hinge assembly (56) is connected between the bracket (5) and the support (2), and the hinge assembly (56) includes: A connecting hoop (561), wherein a hoop body (5611) of the connecting hoop (561) partially surrounds the outer ring wall surface (52) and extends downward at both ends of the hoop body (5611) to form a first connecting leg (5612) and a second connecting leg (5613), a connecting rib (5614) is provided between the first connecting leg (5612) and the second connecting leg (5613), and the lower ends of the first connecting leg (5612) and the second connecting leg (5613) are provided on the sleeve (5615); A rotating shaft (562) is inserted into the sleeve (5615); The hinged frame (563) is arranged on one side of the support (2), and the hinged frame (563) is rotatably connected to the connecting hoop (561) via a rotating shaft (562).
7. The microfluidic detector according to any one of claims 1 to 6, characterized in that: The microfluidic chip (3) has a reaction chamber (31) and a detection chamber (32) therein, and the vibration element (4) acts on the reaction chamber (31).
8. The microfluidic detector according to claim 7, characterized in that: The microfluidic detector further comprises a detection module (7) for detecting optical signals in the detection chamber (32), wherein the detection module (7) is connected to the support (2), and the detection module (7) comprises: A detection cabinet (71), wherein the detection cabinet (71) is provided with a detection groove (711) on a side facing the microfluidic chip (3), the microfluidic chip (3) is partially placed on the lower groove wall of the detection groove (711), and the detection groove (711) covers the detection chamber (32); An emitting sensor (72), wherein a first mounting hole (712) is formed on the lower groove wall of the detection groove (711), the emitting sensor (72) is arranged in the first mounting hole (712), the emitting end of the emitting sensor (72) is arranged upward and directly facing the detection chamber (32), and the emitting sensor (72) serves as a light source and can adjust the wavelength of the light source; A receiving sensor (73), wherein a second mounting hole (713) is formed on the upper groove wall of the detection groove (711), and the receiving sensor (73) is arranged in the second mounting hole (713). The sensing end of the receiving sensor (73) is arranged downward and directly opposite to the detection chamber (32), and is used to receive the light signal emitted by the emitting sensor (72).
9. The microfluidic detector according to claim 7, characterized in that: The support (2) is formed with a mounting cavity (21) below the microfluidic chip (3), and a magnetic field generating module (8) for controlling the movement state of magnetic beads in the reaction chamber (31) is provided at the bottom of the mounting cavity (21).
10. The microfluidic detector according to claim 8, characterized in that: A signal box installation groove (22) is recessed on one side of the support (2), and a signal processing box (9) is arranged in the signal box installation groove (22). The signal processing box (9) is connected to the transmitting sensor (72) and the receiving sensor (73) and is used to control the wavelength of the light source of the transmitting sensor (72) and to receive and process the optical signal received by the receiving sensor (73).
11. The microfluidic detector according to claim 10, characterized in that: A mounting plate (23) is connected to the outward side of the signal box mounting groove (22), and a display screen (10) connected to the signal processing box (9) is provided on the mounting plate (23). The display screen (10) is used to display optical information of the receiving sensor (73) and touch screen input of the wavelength value of the receiving sensor (73).
Citation Information
Patent Citations
Micro-fluidic chip and detector
CN116943758A