Blending device for chemiluminescence immunoassay

Abstract

The utility model discloses a chemiluminescence immunoassay blending device which comprises a mixing rack, a mixing motor is arranged on one side of the mixing rack, a pair of positioning grooves are symmetrically formed in the mixing rack, a pair of rotating seats are assembled in the pair of positioning grooves, a pair of inserting grooves are formed between the pair of rotating seats, and the pair of inserting grooves are matched with the positioning grooves. A supporting rod is arranged between the pair of inserting grooves. The utility model relates to the technical field of uniform mixing in immunoassay, in particular to a uniform mixing device for chemiluminescence immunoassay, which is characterized in that on the basis of a common rotary mixer, an ultrasonic transducer is arranged on one side corresponding to a rotary mixing motor of the rotary mixer, and an extended rod piece is directly and fully contacted with a support rod for placing a reagent tube; ultrasonic vibration generated by the ultrasonic transducer enables the reagent tube on the supporting rod to generate ultrasonic vibration, so that an immunoassay reagent in the reagent tube generates a cavitation effect, and the mixing effect and efficiency are improved.

Description

Technical Field

[0001] The utility model relates to the technical field of immunoassay mixing, in particular to a chemiluminescent immunoassay mixing device. Background Art

[0002] During chemiluminescent immunoassay testing, the chemiluminescent immunoassay reagents need to be mixed. Currently, chemiluminescent immunoassay mixing is mostly performed using a test tube rotary mixer to mix the reagents in the chemiluminescent immunoassay.

[0003] The current rotary mixer is mainly composed of a detachable bracket, a mixing motor and a mixing bracket. However, during the mixing process, the acridinium ester or luminol used in the chemiluminescent immunoassay is not a component that is very easy to mix evenly with the immunoassay. However, since the rotary mixer only has a rotational mixing function, the mixed chemiluminescent immunoassay reagents cannot be quickly mixed, resulting in low mixing efficiency, which leads to a decrease in the overall efficiency of the luminescent immunoassay. In view of this, in-depth research was conducted on the above-mentioned problem, resulting in this case. Utility Model Content

[0004] In view of the deficiencies of the prior art, the utility model provides a chemiluminescence immunoassay mixing device, which solves the problems of the prior art.

[0005] To achieve the above objectives, the utility model is implemented through the following technical solutions: a chemiluminescent immunoassay mixing device, comprising a mixing frame, a mixing motor is arranged on one side of the mixing frame, a pair of positioning grooves are symmetrically arranged on the mixing frame, a pair of rotating seats are assembled in the pair of positioning grooves, a pair of insertion grooves are opened between the pair of rotating seats, and a support rod is arranged between the pair of insertion grooves;

[0006] The support rod is equipped with a placement plate, and a plurality of insertion holes are evenly arranged on the placement plate. A gear set is connected to the driving end of the hybrid motor, and the gear set is connected to one of the rotating seats;

[0007] An ultrasonic transducer is arranged on one side of the mixing frame corresponding to the mixing motor, a vibration rod is connected to the vibration end of the ultrasonic transducer, one end of the vibration rod extends into the insertion slot and is connected to one end of the support rod;

[0008] The end of the vibration rod is a rod of a columnar structure, and the end of the vibration rod passes through one side of the rotating seat. The end of the support rod is provided with a limiting groove, and the vibration rod passes through the limiting groove and contacts the support rod.

[0009] Preferably, the pair of rotating seats are plates of columnar structure, and the pair of rotating seats are connected to the mixing frame by limiting.

[0010] Preferably, the support rod is a plate with a cross-shaped structure, and the middle support frame of the support rod is a columnar structure.

[0011] Preferably, the limiting groove on one side of the support rod and the vibration rod are in transitional fit, the vibration rod is a columnar rod, and the corresponding insertion groove is a columnar groove.

[0012] Beneficial Effects

[0013] The utility model provides a chemiluminescent immunoassay mixing device. It has the following beneficial effects: based on a common rotary mixer, the chemiluminescent immunoassay mixing device is provided with an ultrasonic transducer on the corresponding side of the rotary mixing motor of the rotary mixer, and the extended rod is directly in full contact with the support rod on which the reagent tube is placed, and the ultrasonic vibration generated by the ultrasonic transducer is used to make the reagent tube on the support rod vibrate ultrasonically, so that the immunoassay reagent in the reagent tube undergoes cavitation effect, thereby improving the mixing effect and efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a schematic diagram of the three-dimensional structure of a chemiluminescent immunoassay mixing device described in the utility model.

[0015] Figure 2 This is a schematic diagram of the three-dimensional explosion structure of a chemiluminescent immunoassay mixing device described in the utility model.

[0016] Figure 3 It is a side view cross-sectional structural schematic diagram of a chemiluminescent immunoassay mixing device described in the utility model.

[0017] In the figure: 1. mixing frame; 2. mixing motor; 3. positioning slot; 4. rotating seat; 5. support rod; 6. placement plate; 7. ultrasonic transducer; 8. vibration rod; 9. limit slot. DETAILED DESCRIPTION

[0018] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0019] See also Figure 1-3The utility model provides an implementation scheme: In the modern chemiluminescent immunoassay process, reagents or substrates need to be mixed. At present, a rotary mixer is mostly used for mixing chemiluminescent immunoassay in laboratories. However, acridinium ester or luminol in chemiluminescent immunoassay reagents are substances with high viscosity. Simple shaking mixing often cannot mix them evenly, or the mixing time is long.

[0020] Therefore, in view of the above problems, the present application discloses a chemiluminescent immunoassay mixing device, which is designed based on an existing rotary mixer and adopts a mixing frame 1 as the main body. The mixing frame 1 is a frame of a concave structure, and a mixing motor 2 is arranged on a vertical frame on one side of the mixing frame 1. A pair of positioning grooves 3 are symmetrically arranged on the mixing frame 1, and a pair of rotating seats 4 are assembled in the pair of positioning grooves 3, wherein one of the rotating seats 4 is connected to the driving end of the mixing motor 2 through a gear set, and the mixing motor 2 can drive the rotating seat 4 on this side to rotate, and then drive the rotating seat 4 on the other side to rotate synchronously through the connection effect of the support rod 5, and at the same time, the rotating seats 4 on both sides are arranged relatively to each other, which can support and limit the support rod 5;

[0021] Specifically, a pair of insertion grooves are provided between the pair of rotating seats 4, and the support rod 5 is assembled between the pair of insertion grooves. Specifically, the spline structure on the support rod 5 is used to realize the limited insertion with the insertion groove of the rotating seat 4;

[0022] At the same time, a placement plate 6 is mounted on the support rod 5, and the placement plate 6 is connected to the support rod 5 by a snap-on connection, and a number of insertion holes are evenly arranged on the placement plate 6, through which a number of reagent tubes for luminescent immunoassay are inserted, so as to play a role in installing the reagent tubes. At the same time, a gear set is connected to the driving end of the mixing motor 2, and the gear set is connected to one of the rotating seats 4. During mixing, the mixing motor 2 drives the gear set to rotate, so that the gear set drives the rotating seat 4 to rotate, and then the support rod 5 drives the placement plate 6 and the reagent tubes thereon to rotate, completing the action of rotating mixing;

[0023] Further, in order to improve the mixing effect and efficiency, an ultrasonic transducer 7 is provided on one side of the mixing frame 1 corresponding to the mixing motor 2, and a vibration rod 8 is connected to the vibration end of the ultrasonic transducer 7, one end of the vibration rod 8 extends into the insertion slot and is connected to one end of the support rod 5, and the end of the vibration rod 8 is a rod member of a columnar structure, and the end of the vibration rod 8 passes through one side of the rotating seat 4, and a limiting groove 9 is provided at the end of the support rod 5, and the vibration rod 8 passes through the limiting groove 9 and contacts with the support rod 5;

[0024] During the specific implementation process, an ultrasonic transducer 7 with a vibrating effect is arranged on the side of the mixing motor 2 corresponding to the mixing frame 1, and the ultrasonic transducer 7 drives the vibration rod 8 to vibrate ultrasonically. The vibration rod 8 passes through the rotating seat 4 and does not contact the rotating seat 4, but extends to the limiting groove 9 and contacts the support rod 5 in the limiting groove 9. The ultrasonic transducer 7 transmits the ultrasonic vibration effect to the support rod 5 through the conduction of the vibration rod 8, and then transmits it to the placement plate 6 through the support rod 5, so that the internal reagent of the reagent tube on the placement plate 6 undergoes cavitation under the action of vibration, making the mixing more uniform and rapid.

[0025] As a preferred solution, further, the pair of rotating seats 4 are plates of a columnar structure, and the pair of rotating seats 4 are connected to the mixing frame 1 by a limiting connection to prevent the rotating seats 4 from being separated from the mixing frame 1.

[0026] As a preferred solution, further, the support rod 5 is a cross-shaped structure plate, and the middle support frame of the support rod 5 is a columnar structure, which plays a supporting role on the placement plate 6 through the limiting connection between the support rod 5 and the placement plate 6.

[0027] As a preferred solution, further according to the attached specification Figure 1-3 It can be seen that the limiting groove 9 on one side of the support rod 5 and the vibration rod 8 adopt a transition fit. The vibration rod 8 is a cylindrical rod, and the corresponding insertion groove is a cylindrical groove. The ultrasonic vibration is efficiently transmitted to the support rod 5 through the high fit between the vibration rod 8 and the limiting groove 9.

[0028] From the above, it can be generally known that the chemiluminescent immunoassay mixing device, based on a common rotary mixer, is provided with an ultrasonic transducer 7 on the corresponding side of the rotary mixing motor 2 of the rotary mixer, and an extended rod is used to directly make full contact with the support rod 5 on which the reagent tube is placed, and the ultrasonic vibration generated by the ultrasonic transducer 7 is used to make the reagent tube on the support rod 5 ultrasonically vibrate, thereby causing a cavitation effect on the immunoassay reagent in the reagent tube, thereby improving the mixing effect and efficiency.

[0029] Although the embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A chemiluminescent immunoassay mixing device, comprising a mixing frame (1), a mixing motor (2) is arranged on one side of the mixing frame (1), and a pair of positioning grooves (3) are symmetrically arranged on the mixing frame (1), characterized in that: A pair of rotating seats (4) are installed in the pair of positioning grooves (3), a pair of insertion grooves are provided between the pair of rotating seats (4), and a support rod (5) is provided between the pair of insertion grooves; The support rod (5) is equipped with a placement plate (6), and a plurality of insertion holes are evenly arranged on the placement plate (6). A gear set is connected to the driving end of the hybrid motor (2), and the gear set is connected to one of the rotating seats (4); An ultrasonic transducer (7) is provided on one side of the mixing frame (1) corresponding to the mixing motor (2); a vibration rod (8) is connected to the vibration end of the ultrasonic transducer (7); one end of the vibration rod (8) extends into the insertion slot and is connected to one end of the support rod (5); The end of the vibration rod (8) is a rod of a columnar structure, and the end of the vibration rod (8) passes through one side of the rotating seat (4). The end of the support rod (5) is provided with a limiting groove (9), and the vibration rod (8) passes through the limiting groove (9) and contacts the support rod (5).

2. A chemiluminescent immunoassay mixing device according to claim 1, characterized in that: The pair of rotating seats (4) are plates of a columnar structure, and the pair of rotating seats (4) are connected to the mixing frame (1) in a position-limiting manner.

3. A chemiluminescent immunoassay mixing device according to claim 2, characterized in that: The support rod (5) is a plate with a cross-shaped structure, and the middle support frame of the support rod (5) is a columnar structure.

4. A chemiluminescent immunoassay mixing device according to claim 3, characterized in that: The limiting groove (9) on one side of the support rod (5) and the vibration rod (8) adopt transitional matching; the vibration rod (8) is a columnar rod, and the corresponding insertion groove is a columnar groove.

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