Pipetting and sampling structure for sixteen-pore plate

Abstract

The utility model discloses a pipetting and sample adding structure for a sixteen-hole plate, which comprises a pipetting component and a sample adding component, a support assembly; the supporting assembly comprises a supporting frame placed on the outer side of the sixteen-hole plate, a pulley slidably connected to the inner position of the upper end of the supporting frame, a moving plate fixedly connected to the top end of the pulley, first hollow grooves formed in the two sides of the moving plate, and telescopic springs fixedly connected to the inner positions of the first hollow grooves. The movable block is fixedly connected to the outer end of the telescopic spring; the second hollow groove is formed in the outer side face of the supporting frame; and a movable assembly. The utility model solves the problems that when a pipettor is used for adding a biological sample solution into holes of an existing sixteen-hole plate, the biological sample solution needs to be added for several times, the dropping pipettes need to be kept flush with the sixteen-hole plate due to the fact that the number of the dropping pipettes is large during adding, otherwise, the biological sample solution is dropped out from the upper end of the sixteen-hole plate, and the number of the dropping pipettes is large. And time is wasted when the dropping pipette and the sixteen-hole plate are aligned.

Description

Technical Field

[0001] The utility model relates to the technical field of liquid transfer and sample addition equipment, in particular to a liquid transfer and sample addition structure for a sixteen-well plate. Background Art

[0002] A sixteen-well plate is a plate used in biomedicine, and sixteen groups of holes are provided on its upper end for placing biological samples or cell samples. During the use of the sixteen-well plate, a pipette is required to add the sample solution into the interior of the sixteen-well plate.

[0003] However, it still has the following disadvantages in actual use:

[0004] When adding biological sample solutions into the wells of the existing 16-well plate using a pipette, the addition needs to be performed in batches. When adding, due to the large number of dropper tubes, the dropper tubes need to be kept flush with the 16-well plate, otherwise the biological sample solution will drip out from the upper end of the 16-well plate, which wastes time in aligning the dropper tubes with the 16-well plate.

[0005] Therefore, a new pipetting structure for a sixteen-well plate is proposed to solve the above problems. Utility Model Content

[0006] Technical issues to be solved

[0007] The utility model aims to provide a pipetting sample adding structure for a sixteen-well plate, so as to solve the problem in the above-mentioned background technology that when adding biological sample solution into the wells of the existing sixteen-well plate using a pipette, the addition needs to be performed in batches. When adding, due to the large number of dropper tubes, the dropper tube and the sixteen-well plate need to be kept flush, otherwise the biological sample solution will drip out from the upper end of the sixteen-well plate, and it is time-consuming to align the dropper tube and the sixteen-well plate.

[0008] Technical Solution

[0009] In order to solve the above technical problems, the utility model is realized by the following technical solutions:

[0010] The utility model is a liquid transfer and sample adding structure for a sixteen-well plate, comprising:

[0011] a pipetting assembly, including a sixteen-well plate;

[0012] Support assembly; the support assembly includes a support frame placed at the outer side of the sixteen-hole plate, a pulley slidably connected to the inner position of the upper end of the support frame, a movable plate fixedly connected to the top position of the pulley, a first hollow groove opened at both sides of the movable plate, a telescopic spring fixedly connected to the inner position of the first hollow groove, a movable block fixedly connected to the outer end position of the telescopic spring, and a second hollow groove opened on the outer side of the support frame;

[0013] The movable component is fixedly connected to the rear side of the support frame.

[0014] Furthermore, the pipetting assembly also includes a dropper placed above the sixteen-well plate and a pipette fixedly connected to the upper end of the dropper;

[0015] Specifically, the pipette is used to suck the biological sample solution into the inside of the dropper, the dropper is used to place the biological sample solution, and the sixteen-well plate is used to observe or react the biological sample.

[0016] Furthermore, the upper end of the support frame has a hollow structure opened relative to the pulley, and the support frame is a U-shaped structure;

[0017] Specifically, the pulley can move on the upper end of the support frame, and when the pulley moves, it will drive the moving plate to move.

[0018] Further, the first hollow groove and the second hollow groove are opened relative to the movable block, and the center line of the second hollow groove is collinear with the center line of the first hollow groove;

[0019] Specifically, when the movable block is located in the first hollow groove, the telescopic spring is in a compressed state, and when the movable block is located in the second hollow groove, the telescopic spring is in a stress-free state, and the front end of the movable block is an arc-shaped structure.

[0020] Furthermore, the upper end of the movable plate has a T-shaped groove opened relative to the pipette, and the movable plate is located above the sixteen-well plate;

[0021] Specifically, the pipette can be placed on the upper end of the movable plate, and when the movable plate moves, the pipette can be driven to move.

[0022] Further, the movable component includes a protective plate fixedly connected to the rear end position of the inner side of the support frame, a rotating shaft rotatably connected to the lower end position of the inner side of the support frame, a driven shaft rotatably connected to the upper end position of the inner side of the support frame, and a protective film whose outer end is fixedly connected to the rear side surface of the movable plate;

[0023] Specifically, the protective plates are located on both sides of the rotating shaft and the driven shaft. The rotating shaft is used to place the protective film, the driven shaft is used to keep the protective film and the moving plate parallel, and the protective film is used to block the upper end of the sixteen-hole plate.

[0024] Furthermore, a section of the protective film is fixed on the outer surface of the rotating shaft, the inner side of the protective film is in contact with the outer surface of the driven shaft, and a coil spring is fixedly connected inside the rotating shaft;

[0025] Specifically, when the protective film moves outward under the pull of the moving block, the rotating shaft rotates forwardly, and when the moving block moves reversely, the protective film is rolled up under the drive of the coil spring and the rotating shaft.

[0026] Beneficial Effects

[0027] Compared with the prior art, the advantages of the present invention are:

[0028] 1. The utility model provides a fixed component so that when pipetting and adding samples to a sixteen-well plate, there is no need to visually align the dropper with the holes of the sixteen-well plate. The pipette only needs to be placed on the upper end of the movable plate and moved under the drive of the movable plate. The movable plate moves to the inside of the second hollow groove through the movable block to align the dropper with the holes of the sixteen-well plate.

[0029] 2. Based on the first beneficial effect, by setting up a movable component, when pipetting and adding samples to a 16-well plate, the protective film is driven by the movable plate to block the upper end of the well where the sample has been added, thereby avoiding contamination caused by misoperation or leakage of the dropper.

[0030] Of course, any product implementing the present invention does not necessarily need to achieve all of the advantages described above at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] In order to more clearly illustrate the technical solutions of the embodiments of the utility model, the drawings required for describing the embodiments are briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0032] Figure 1 This is the front view of the utility model;

[0033] Figure 2 This is a structural diagram of the liquid transfer component of the utility model;

[0034] Figure 3 This is a structural diagram of the support assembly of the utility model;

[0035] Figure 4 This is a structural diagram of the active components of the utility model.

[0036] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0037] 1. Liquid transfer assembly; 11. Sixteen-well plate; 12. Dropper; 13. Pipette; 2. Support assembly; 21. Support frame; 22. Pulley; 23. Moving plate; 24. First hollow groove; 25. Telescopic spring; 26. Movable block; 27. Second hollow groove; 3. Movable assembly; 31. Protective plate; 32. Rotating shaft; 33. Driven shaft; 34. Protective film. DETAILED DESCRIPTION

[0038] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below with reference to the accompanying drawings.

[0039] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific implementation methods disclosed below.

[0040] Secondly, the present invention is described in detail with reference to the schematic diagram. When describing the implementation of the present invention, for the sake of convenience, the cross-sectional diagram showing the device structure will not be partially enlarged according to the general scale, and the schematic diagram is only an example, which should not limit the scope of protection of the present invention. In addition, in actual production, the three-dimensional dimensions of length, width and depth should be included.

[0041] In order to make the purpose, technical solution and advantages of the present invention more clear, the implementation mode of the present invention will be further described in detail below with reference to the accompanying drawings.

[0042] Example 1

[0043] See also Figure 1-3 As shown, this embodiment is a liquid transfer sample adding structure for a sixteen-well plate, comprising:

[0044] The liquid transfer assembly 1 comprises a sixteen-well plate 11;

[0045] Support assembly 2; the support assembly 2 includes a support frame 21 placed at the outer side of the sixteen-hole plate 11, a pulley 22 slidably connected to the inner position of the upper end of the support frame 21, a movable plate 23 fixedly connected to the top position of the pulley 22, a first hollow groove 24 opened at both sides of the movable plate 23, a telescopic spring 25 fixedly connected to the inner position of the first hollow groove 24, a movable block 26 fixedly connected to the outer end position of the telescopic spring 25, and a second hollow groove 27 opened on the outer side of the support frame 21;

[0046] The movable component 3 is fixedly connected to the rear side of the support frame 21;

[0047] The liquid transfer assembly 1 further comprises a dropper 12 placed above the 16-well plate 11 and a pipette 13 fixedly connected to the upper end of the dropper 12;

[0048] The upper end of the support frame 21 has a hollow structure opened relative to the pulley 22, and the support frame 21 is a U-shaped structure;

[0049] The first hollow groove 24 and the second hollow groove 27 are opened relative to the movable block 26, and the center line of the second hollow groove 27 is collinear with the center line of the aperture of the sixteen-hole plate 11;

[0050] The upper end of the movable plate 23 has a T-shaped groove opened relative to the pipette 13, and the movable plate 23 is located above the sixteen-well plate 11;

[0051] How to use the support assembly 2, the following steps are published:

[0052] When it is necessary to add samples to the sixteen-hole plate 11, the sample is sucked into the dropper 12 through the pipette 13, and then the pipette 13 is placed in the inner position of the upper end of the movable plate 23. At this time, since the movable plate 23 and the sixteen-hole plate 11 remain parallel, the dropper 12 and the holes of the sixteen-hole plate 11 remain parallel, and then an outward force is applied to the movable plate 23, so that the movable plate 23 moves on the upper end of the support frame 21 driven by the pulley 22. Since the movable block 26 is blocked by the outer side of the support frame 21, the movable block 26 generates pressure on the telescopic spring 25 and drives the inside of the first hollow groove 24. When the movable plate 23 moves to the outer end of the second hollow groove 27 where the movable block 26 is located, the outer end of the movable block 26 is not subjected to force and moves outward under the elastic force of the telescopic spring 25. Since the center line of the second hollow groove 27 is collinear with the center line of the first hollow groove 24, the dropper 12 is located directly above the hole.

[0053] In this step, there is no need to visually align the dropper 12 and the sixteen-well plate 11 , and the dropper 12 can be ensured to be located directly above the holes of the sixteen-well plate 11 by simply pushing the movable plate 23 .

[0054] Example 2

[0055] See also Figure 4 As shown, this embodiment is based on the above embodiment 1 and also includes:

[0056] The movable component 3 is fixedly connected to the rear side of the support frame 21;

[0057] The movable assembly 3 includes a protective plate 31 fixedly connected to the inner rear end of the support frame 21, a rotating shaft 32 rotatably connected to the lower end of the inner rear end of the support frame 21, a driven shaft 33 rotatably connected to the upper end of the inner rear end of the support frame 21, and a protective film 34 whose outer end is fixedly connected to the rear side of the movable plate 23;

[0058] A section of the protective film 34 is fixed on the outer surface of the rotating shaft 32, the inner side of the protective film 34 is in contact with the outer surface of the driven shaft 33, and a coil spring is fixedly connected inside the rotating shaft 32;

[0059] How to use activity component 3, publish the following steps:

[0060] After the movable plate 23 drives the pipette 13 to drip liquid, it is necessary to push the movable plate 23 outward to align with the next group of holes. During the movement of the movable plate 23, the protective film 34 is pulled outward, and the protective film 34 drives the rotating shaft 32 to rotate, and is always kept flush with the movable plate 23 through the driven shaft 33. The protective film 34 can block the upper end of the sixteen-well plate 11 after the sample is added.

[0061] When the moving plate 23 moves inward to reset, the rotating shaft 32 rotates in the opposite direction under the drive of the coil spring, and the rotating shaft 32 rotates in the opposite direction to wind the protective film 34 .

[0062] In this step, when the pipette 13 is driven by the movable plate 23 to drip liquid, the movable plate 23 will drive the protective film 34 to cover the upper end of the sixteen-well plate 11 on which the sample has been added, thereby preventing contamination caused by leakage.

[0063] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0064] Finally, it should be noted that the above description is only a preferred embodiment of the utility model and is not intended to limit the utility model. Although the utility model is described in detail with reference to the above embodiments, those skilled in the art can still modify the technical solutions recorded in the above embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.

Claims

1. A liquid transfer sample adding structure for a sixteen-well plate, characterized in that: include: A liquid transfer assembly (1) comprising a sixteen-well plate (11); A support assembly (2); the support assembly (2) comprises a support frame (21) placed at an outer position of a sixteen-hole plate (11), a pulley (22) slidably connected to an inner position of an upper end of the support frame (21), a movable plate (23) fixedly connected to a top position of the pulley (22), a first hollow groove (24) provided at positions on both sides of the movable plate (23), a telescopic spring (25) fixedly connected to an inner position of the first hollow groove (24), a movable block (26) fixedly connected to an outer end position of the telescopic spring (25), and a second hollow groove (27) provided on an outer surface of the support frame (21); The movable component (3) is fixedly connected to the rear side of the support frame (21).

2. A sixteen-well plate pipetting structure according to claim 1, characterized in that: The liquid transfer assembly (1) further comprises a dropper (12) placed above the sixteen-well plate (11) and a pipette (13) fixedly connected to the upper end of the dropper (12).

3. A sixteen-well plate pipetting structure according to claim 1, characterized in that: The upper end of the support frame (21) has a hollow structure opened relative to the pulley (22), and the support frame (21) is a U-shaped structure.

4. A sixteen-well plate pipetting structure according to claim 1, characterized in that: The first hollow groove (24) and the second hollow groove (27) are opened relative to the movable block (26), and the center line of the second hollow groove (27) is colinear with the center line of the first hollow groove (24).

5. The liquid transfer and sample loading structure for a sixteen-well plate according to claim 1, characterized in that: The upper end of the movable plate (23) is provided with a T-shaped groove which is opened relative to the pipette (13), and the movable plate (23) is located above the sixteen-hole plate (11).

6. The liquid transfer and sample loading structure for a sixteen-well plate according to claim 1, characterized in that: The movable component (3) comprises a protective plate (31) fixedly connected to the inner rear end position of the support frame (21), a rotating shaft (32) rotatably connected to the lower end position of the inner rear end of the support frame (21), a driven shaft (33) rotatably connected to the upper end position of the inner rear end of the support frame (21), and a protective film (34) whose outer end is fixedly connected to the rear side surface of the movable plate (23).

7. A sixteen-well plate pipetting structure according to claim 6, characterized in that: One end of the protective film (34) is fixed on the outer surface of the rotating shaft (32), the inner side of the protective film (34) is in contact with the outer surface of the driven shaft (33), and a coil spring is fixedly connected inside the rotating shaft (32).

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