Wrapping type rat fixing device

Abstract

The utility model discloses a wrapping type rat fixing device, which belongs to the technical field of medical animal experiments, and is technically characterized by comprising a grid base, a head fixing belt and a trunk wrapping belt, the grid base is made of a planar net-shaped stainless steel material, and internal steel wires of the grid base can be tailored according to the body type of a rat; the base is connected with the head fixing belt and the trunk wrapping belt, the head fixing belt is formed by splicing a hook-and-loop fastener with a hook face and a loop face in a front-and-back mode, the head fixing belt is arranged above the trunk wrapping belt and used for fixing the head position of a rat, and the trunk wrapping belt is formed by sewing a piece of rectangular coarse cotton cloth and two pieces of rectangular hook-and-loop fasteners. The rat fixing device is arranged at the reserved position in the center of the grid base and used for wrapping the upper limbs, the trunk and the buttocks of a rat, is suitable for animal experiments of non-invasive intervention treatment, can effectively fix rats of different figures and reduce stress behaviors of the rats in the experiment process, and has the advantages of being stable in structure, low in cost, easy to operate and easy to clean and store.

Description

Technical Field

[0001] The utility model relates to the field of medical animal experiments, in particular to a wrapped rat fixing device. Background Art

[0002] At present, with the gradual deepening and development of basic medical experiments, the instruments for specific animal experiments are also constantly enriched. Therefore, a variety of rat fixators have appeared on the market, which are mainly used to facilitate experimenters to fix rats during animal experiments, so as to carry out a series of interventions (acupuncture at different parts, stereotaxic injection of the brain, intraperitoneal injection, gavage) or sampling (blood sampling from the tail vein) and other experimental operations.

[0003] However, traditional rat fixators are complex in structure, expensive, and difficult to store, and can no longer meet the needs of large-scale animal experiments. In addition, for some non-invasive treatment methods, such as transauricular vagus nerve stimulation, transcranial magnetic stimulation, transcranial direct current stimulation, trigeminal nerve stimulation, and ear bean pressure points, these intervention methods act directly on the body to exert therapeutic effects. Rats will not feel pain during the treatment process and only need to keep their bodies stable. However, most rat fixators on the market are made of acrylic, and the control over the rat's body shape is very limited. Rats are extremely prone to rolling and struggling in the fixator, accompanied by strong discomfort and stress behavior.

[0004] Studies have found that heavy quilts can mimic the feeling of being hugged and caressed. Using heavy quilts can increase the amount of melatonin naturally produced in the body (melatonin is a hormone that helps sleep), help the body relax, and thus get a better sleep. Similarly, the pressure applied by the trunk wrapping belt used in the utility model can increase the tactile and thermal stimulation of the rat's body, activate the rat's skin sensory nerve conduction mechanism, and transmit sensory information to the solitary nucleus through the spinal cord. After the solitary nucleus receives the "pressure" signal, it further projects it to the paraventricular nucleus of the hypothalamus. The paraventricular nucleus neurons can not only produce oxytocin to enhance the rat's inner peace and happiness, reduce fear, stress and pain, but these neurons are also connected to the pineal gland, thereby promoting the release of melatonin to produce a sense of security and relaxation.

[0005] Relevant studies have shown that the occurrence of stress behavior in animals will prompt the body to release stress cytokines, such as pro-inflammatory cytokines, corticosteroids and apoptotic cytokines, which will then activate the hypothalamus-pituitary-adrenal axis and have irreversible effects on the body and brain development, resulting in biased experimental results that cannot meet the needs of actual use.

[0006] Therefore, it is necessary to provide a wrapping rat fixing device to solve the above problems. Utility Model Content

[0007] In view of the deficiencies in the prior art, the purpose of the embodiments of the present utility model is to provide a wrapped rat fixation device, aiming to solve the technical problems raised in the background technology.

[0008] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0009] A wrapping rat fixing device comprises a mesh base, a head fixing belt and a trunk wrapping belt, wherein a plurality of spaces are cut out on the mesh base to accommodate the head fixing belt and the trunk wrapping belt for fixing the rat;

[0010] The head fixing strap is made of two Velcro strips with the front and back sides connected together. The width of the head fixing strap is based on the width of a single grid on the grid base, which is generally 0.8 to 1.2 cm. It is inserted into the reserved position in the grid base and fixed above the torso wrapping strap.

[0011] The torso wrap is composed of a rectangular piece of coarse cotton cloth and two pieces of Velcro (one hook side and one fleece side). The hook side is located on the left side of the front side of the torso wrap, and the fleece side is located on the right side of the back side of the torso wrap. The front side of the torso wrap is placed in the central space of the base with a reserved gap, below the head fixing strap.

[0012] As a further solution of the utility model, the grid base is a mesh structure, and the same fixing frame is cut into stainless steel grids multiple times according to experimental requirements. Generally, a 40 cm long grid fixing frame can fix 2 to 3 adult rats (220±20g) at the same time.

[0013] As a further solution of the utility model, the front side of the trunk wrapping belt is inserted into the space cut out in the center of the grid base, and the front Velcro hook surface and the back Velcro fleece surface are adhered to wrap the upper limbs, trunk and buttocks of the rat.

[0014] In summary, the embodiments of the present invention have the following beneficial effects compared with the prior art:

[0015] 1. The fixed base adopted is a flat mesh structure, which has the following three advantages: 1. The contact area between the flat structure fixing device and the desktop is increased, making the overall device more solid, not prone to displacement, and easy to store; 2. The mesh structure can facilitate the experimenter to position and adjust according to the body shape of the rat, so as to create a wrapping and fixing device that fully fits the body shape of the rat, and the grid structure can completely clamp the head fixing strap and the torso wrapping strap to prevent the fixing device from slipping during the experiment; 3. The mesh hollow stainless steel material is more convenient for cleaning the rat's excrement; it solves the disadvantages of traditional rat fixers, which are mostly made of three-dimensional acrylic material, with a variety of parts, and the material is bulky and difficult to store.

[0016] 2. The trunk wrapping strap used is made of cheesecloth and Velcro. Cheesecloth is the main material and has the following advantages: 1. It is soft, comfortable, and inelastic, with strong wrapping properties for rats and a higher fit; 2. The rough surface can greatly increase the friction between the rat and the cotton cloth, preventing the rat from slipping during the experiment; 3. It is thick and wear-resistant, which can prevent the rat from wearing the wrapping strap during the experiment; in addition, Velcro can be adhered and adsorbed according to the rat's body shape, so a single experimenter can easily fix the rat's upper limbs, trunk and buttocks.

[0017] 3. The head fixing strap is made of two Velcro strips (one hook side and one fleece side) spliced ​​together front and back, and inserted into the mesh base to fix the position of the rat's head. The Velcro strips have strong adhesion and moderate width, which can effectively prevent the rat from suffocating and produce a wrapping effect.

[0018] In order to more clearly illustrate the structural features and functions of the present invention, the present invention is described in detail below in conjunction with the accompanying drawings and specific embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic structural diagram of an embodiment of the utility model.

[0020] Figure 2 It is a schematic diagram of the animal effect state of the utility model embodiment.

[0021] Figure numerals: 1. grid base; 2. head fixing strap; 3. torso wrapping strap; 4. space. DETAILED DESCRIPTION

[0022] In order to make the purpose, technical solution and advantages of the utility model more clear, the utility model is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the utility model and are not used to limit the utility model.

[0023] The specific implementation of the present utility model is described in detail below in conjunction with specific embodiments.

[0024] See also Figure 1-2 A wrapping rat fixing device comprises a mesh base 1, a head fixing belt 2 and a trunk wrapping belt 3, wherein a plurality of spaces 4 are cut out on the mesh base 1 to accommodate the head fixing belt 2 and the trunk wrapping belt 3 for fixing the rat;

[0025] The head fixing strap 2 is made of two Velcro strips with front and back sides spliced ​​together. The width of the head fixing strap 2 is based on the width of a single grid on the grid base 1. The head fixing strap 2 is inserted into a reserved position in the grid base 1 and fixed above the torso wrapping strap 3.

[0026] The torso wrapping strap 3 is composed of a rectangular piece of coarse cotton cloth and two pieces of Velcro, the hook surface is located on the left side of the front side of the torso wrapping strap 3, and the fleece surface is located on the right side of the back side of the torso wrapping strap 3. The front side of the torso wrapping strap 3 is placed in the central space 4 of the base with a reserved gap, and is located below the head fixing strap 2.

[0027] Furthermore, the grid base 1 is a mesh structure, and the same fixing frame can cut the stainless steel grid multiple times according to experimental requirements.

[0028] Furthermore, the front side of the trunk wrapping belt 3 is inserted into the space 4 cut out in the center of the grid base 1, and the front Velcro hook surface and the back Velcro fleece surface are adhered to wrap the upper limbs, trunk and buttocks of the rat.

[0029] Preferably, the base of the fixing frame is a planar mesh structure, and the planar structure can increase the contact area between the fixing frame and the desktop, thereby increasing the overall stability of the device;

[0030] The mesh structure makes it easy for experimenters to cut and position the grid so as to reserve a fixed position that best suits the body shape of the experimental rat, thereby better fixing the rat.

[0031] The same fixed base can be used to cut the stainless steel grid multiple times according to experimental requirements. Generally, a 40 cm long grid fixing frame can fix 2 to 3 adult rats (220 ± 20 g) at the same time.

[0032] The trunk wrapping belt 3 is made of cheesecloth and Velcro, and the front side is inserted into the space 4 cut in the center of the base of the fixing frame. The cheesecloth is soft and comfortable, inelastic, and has a large contact surface resistance. The Velcro hook surface on the front side and the Velcro fleece surface on the back side are glued together to completely wrap the upper limbs, trunk and buttocks of the rat, so that the rat is in a wrapped safe environment, increasing the comfort of the rat and reducing the stress behavior of the rat.

[0033] That is, through the study published in the Journal of Sleep Research, this is the reason why the rats did not show stress behavior and showed a sense of security and comfort when we used this fixture to wrap the rats. In addition, rats have a natural tendency to dig holes, and the Velcro of the trunk wrap is fixed in a cylindrical structure, so rats often actively drill into the wrap. The experimenter can operate alone, reducing the workload and making it more convenient and quick.

[0034] It should be noted that the contents not described in detail in this specification belong to the prior art known to professional and technical personnel in this field.

[0035] It should be particularly noted that the components in this application are all universal standard parts or components well known to those skilled in the art, which effectively solve the technical problems raised in the background technology.

[0036] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A wrapped rat fixation device, characterized in that: The invention comprises a mesh base (1), a head fixing belt (2) and a trunk wrapping belt (3), wherein a plurality of spaces (4) are cut out on the mesh base (1) to accommodate the head fixing belt (2) and the trunk wrapping belt (3) for fixing rats; The trunk wrapping belt (3) is composed of a rectangular piece of coarse cotton cloth and two pieces of Velcro, the hook surface is located on the left side of the front side of the trunk wrapping belt (3), and the fleece surface is located on the right side of the back side of the trunk wrapping belt (3). The front side of the trunk wrapping belt (3) is placed in a reserved gap in the central space (4) of the base, and is located below the head fixing belt (2).

2. The wrapped rat fixing device according to claim 1, characterized in that: The head fixing strap (2) is formed by splicing two Velcro strips on the front and back. The width of the head fixing strap (2) is based on the width of a single grid on the grid base (1). The head fixing strap (2) is inserted into a reserved position in the grid base (1) and fixed above the torso wrapping strap (3).

3. The wrapped rat fixing device according to claim 1, characterized in that: The grid base (1) is a mesh structure, which is cut to provide a plurality of spaces (4) that can be fixed according to the body shape of the rat.

4. The wrapped rat fixing device according to claim 1, characterized in that: The front side of the trunk wrapping belt (3) is inserted into the space (4) cut out in the center of the grid base (1), and the front Velcro hook surface and the back Velcro fleece surface are adhered to complete the wrapping and fixing of the rat's upper limbs, trunk and buttocks.

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