RNA extraction and purification kit

Abstract

The utility model provides an RNA (Ribonucleic Acid) extraction and purification kit, which comprises a cylindrical box body, a semiconductor chilling plate is arranged at the bottom of the cylindrical box body, a plurality of windows are arranged on the periphery of the cylindrical box body, a drawing frame body is arranged in each window, a test tube support ring and a test tube bottom support are respectively arranged at the top and the bottom in each drawing frame body, and the test tube support rings and the test tube bottom supports are arranged in the cylindrical box body. A front sealing plate and a rear sealing plate which are matched with the window in a sealing mode are arranged on the front side and the rear side of the drawing frame body respectively, and the two sides of the drawing frame body are in a hollowed-out state. According to the test tube box, the drawing frame body of the drawer type structure is arranged on the peripheral wall of the cylindrical box body, the drawing frame body has the function of placing the test tubes, when the drawing frame body is opened, the test tubes can be freely taken and placed, and the test tube box has the advantage that the test tubes can be taken and placed more conveniently.

Description

Technical Field

[0001] The utility model relates to the technical field of kits, in particular to an RNA extraction and purification kit. Background Art

[0002] A test kit is a box used to hold chemical reagents for testing chemical components, drug residues, virus types, etc. It is generally used in hospitals and pharmaceutical companies. Ribonucleic acid (abbreviated as RNA) is a genetic information carrier present in biological cells and some viruses and viroids. RNA is formed by the condensation of ribonucleotides through phosphodiester bonds to form a long chain molecule. A ribonucleotide molecule is composed of phosphate, ribose and bases. There are four main bases in RNA, namely A adenine, G guanine, C cytosine, and U uracil. Among them, U (uracil) replaces T in DNA.

[0003] At present, the utility model with announcement number CN212891546U proposes an RNA purification kit, including a box body, a sleeve is fixedly installed on the bottom central inner wall of the box body, and a spring is fixedly installed on the bottom inner wall of the sleeve, a plug rod is fixedly installed on the top outer wall of the spring, and the plug rod is plugged with the sleeve, and a second support plate is fixedly installed on the circumferential top inner wall of the box body, and the top outer wall of the second support plate is provided with a first opening distributed in an annular array, and the inner walls on both sides of the first opening are connected to a rotating rod through a bearing. The RNA purification kit proposed by the utility model is provided with a second support plate inside the box body, and a first opening distributed in an annular array is provided on the second support plate, and an annular support plate and a rotating rod are provided in the first opening. When inserting the reagent tube into the annular support plate for placement, it can be directly inserted at an angle, and then the reagent tube is vertically inserted along the rotating rod, which improves the convenience of placement and material extraction.

[0004] However, the above-mentioned prior art still has some shortcomings when used: 1. When placing the test tube, it is necessary to tilt and align the rotating annular support plate, which has the defect of being difficult to dock, thereby increasing the difficulty of taking and placing the test tube. 2. When placing the test tube, the top cover needs to be opened, and when all the test tubes are placed, the top cover is covered again. When extracting the test tube, the top cover also needs to be opened. When the top cover is opened, all the test tubes are exposed, which affects the heat preservation and dustproof effects of other test tubes.

[0005] To this end, the utility model provides an RNA extraction and purification kit. Utility Model Content

[0006] In view of the deficiencies in the prior art, the purpose of the present invention is to provide an RNA extraction and purification kit to solve the problems raised in the above-mentioned background technology. The present invention has the advantages of more convenient test tube placement and better sealing and heat preservation.

[0007] In order to achieve the above-mentioned purpose, the utility model is realized through the following technical scheme: an RNA extraction and purification kit, comprising a cylindrical box body, a semiconductor refrigeration sheet is arranged at the bottom of the cylindrical box body, a plurality of windows are opened on the outer circumference of the cylindrical box body, a pull-out frame is arranged in the window, a test tube support ring and a test tube bottom support are arranged at the top and bottom of the pull-out frame respectively, a front sealing plate and a rear sealing plate which are sealed with the window are arranged at the front and rear sides of the pull-out frame respectively, and both sides of the pull-out frame are in a hollow state.

[0008] Furthermore, slide grooves are provided on both sides of the window, and limiting blocks that slide in cooperation with the slide grooves are welded on both sides of the drawer frame.

[0009] Furthermore, a circle of sealing rubber pads are bonded to the opposite sides of the front sealing plate and the rear sealing plate, a column located in the middle is arranged in the cylindrical box body, a support spring is arranged between the column and the rear sealing plate, the front side of the front sealing plate is rotatably connected to a limiting rod, and the outer peripheral wall of the cylindrical box body is welded with L-shaped hook plates located on the upper and lower sides of the front sealing plate.

[0010] Furthermore, a positioning shaft is welded to the middle of the front side of the front sealing plate, and a positioning hole rotatably connected to the positioning shaft is opened in the middle of the limiting rod.

[0011] Furthermore, a handle is welded on the front side of the limiting rod.

[0012] Furthermore, a supporting leg is provided at the bottom of the cylindrical box body, and a suction cup is provided at the bottom of the supporting leg.

[0013] Furthermore, a groove frame is welded to the top of the supporting leg, the top of the groove frame is welded to the bottom of the cylindrical box body, the bottom of the supporting leg is connected to a turntable, and the suction cup is arranged at the bottom of the turntable.

[0014] Furthermore, the turntable is provided with a plurality of connection holes close to the outer periphery, and the top of the suction cup is provided with an integral pile column which is adhesively connected to the connection holes.

[0015] The beneficial effects of the utility model are as follows:

[0016] 1. The utility model provides a drawer-type pull-out frame on the outer peripheral wall of the cylindrical box body. The pull-out frame has the function of placing test tubes. When the pull-out frame is opened, the test tubes can be freely taken in and out, which has the advantage of being more convenient for taking in and out of the test tubes.

[0017] 2. The utility model improves the dustproofness and sealing of the box body by keeping the inner cavity of the cylindrical box body in a closed state when the pull-out frame body is set to be opened and closed, and makes the temperature inside the cylindrical box body in a constant state, thereby ensuring the cooling effect of the cylindrical box body on the test tube.

[0018] 3. The utility model arranges a support spring in the cylindrical box body, and then arranges a limit rod on the front side of the pull-out frame body, the limit rod is rotatably arranged, and then an L-shaped hook plate is arranged on the outer wall of the cylindrical box body, so that the pull-out operation of the pull-out frame body is more convenient, wherein a test tube support ring and a test tube bottom support are arranged in the pull-out frame body for placing the test tube, and this arrangement makes it more convenient to take and put the test tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the structure of an RNA extraction and purification kit of the utility model after explosion expansion;

[0020] Figure 2 for Figure 1 The main view;

[0021] Figure 3 It is a schematic diagram of the connection between the semiconductor cooling sheet and the cylindrical box body of an RNA extraction and purification kit of the utility model;

[0022] In the figure: 1. cylindrical box body; 11. column; 12. L-shaped hook plate; 13. leg; 131. slotted frame; 132. turntable; 1321. connecting hole; 2. semiconductor cooling plate; 5. window; 51. slide; 6. pull-out frame; 61. limit block; 7. test tube support ring; 8. test tube bottom support; 9. front sealing plate; 91. positioning shaft; 101. rear sealing plate; 102. sealing pad; 103. support spring; 104. limit rod; 1041. positioning hole; 1042. handle; 105. suction cup; 1051. pile column. DETAILED DESCRIPTION

[0023] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.

[0024] See also Figures 1 to 3 The utility model provides a technical solution: an RNA extraction and purification kit, comprising a cylindrical box body 1, a semiconductor refrigeration sheet 2 is arranged at the bottom of the cylindrical box body 1, the inner cavity of the cylindrical box body 1 is a closed structure, the cooling surface of the semiconductor refrigeration sheet 2 is located in the inner cavity of the cylindrical box body 1, and the cylindrical box body 1 can be cooled.

[0025] A plurality of windows 5 are provided on the outer circumference of the cylindrical box body 1, and a draw-out frame body 6 is provided in the window 5. Specifically, slide grooves 51 are provided on both sides of the window 5, and limit blocks 61 are welded on both sides of the draw-out frame body 6 to slide with the slide grooves 51. A test tube support ring 7 and a test tube bottom support 8 are provided on the top and bottom of the draw-out frame body 6, respectively. The test tube support ring 7 limits the position of the test tube, and the test tube bottom support 8 supports the test tube. When the frame body 6 is drawn out, the test tube will switch inside and outside the cylindrical box body 1, which is convenient for storing and taking the test tube.

[0026] The front and rear sides of the pull-out frame 6 are respectively provided with a front sealing plate 9 and a rear sealing plate 101 which are sealed with the window 5. When the pull-out frame 6 is opened, the rear sealing plate 101 seals the window 5. When the pull-out frame 6 is closed, the front sealing plate 9 seals the window 5. Both sides of the pull-out frame 6 are hollow, which makes it easier for cold air to surround the test tube.

[0027] Specifically, a circle of sealing rubber pad 102 is bonded to the opposite sides of the front sealing plate 9 and the rear sealing plate 101 , and the sealing rubber pad 102 serves to seal the gap between the front sealing plate 9 and the rear sealing plate 101 and the cylindrical box body 1 .

[0028] Furthermore, a column 11 is provided in the middle of the cylindrical box body 1, and the top of the column 11 is welded and connected to the top of the cylindrical box body 1. A support spring 103 is provided between the column 11 and the rear sealing plate 101, and the support spring 103 applies an outward elastic thrust to the drawer frame 6 through the rear sealing plate 101. The front side of the front sealing plate 9 is rotatably connected to a limit rod 104. Specifically, a positioning shaft 91 is welded in the middle of the front side of the front sealing plate 9, and a positioning hole 1041 is provided in the middle of the limit rod 104 that is rotatably connected to the positioning shaft 91. The outer peripheral wall of the cylindrical box body 1 is welded with L-shaped hook plates 12 located on the upper and lower sides of the front sealing plate 9. When the drawer frame 6 is closed and the limit rod 104 is rotated, the two ends of the limit rod 104 will enter the L-shaped hook plate 12 to lock the drawer frame 6.

[0029] In this embodiment, a handle 1042 is welded to the front side of the limiting rod 104 , and the handle 1042 is an operating component for manually controlling the rotation of the limiting rod 104 .

[0030] In this embodiment, the bottom of the cylindrical box body 1 is provided with a leg 13, and the bottom of the leg 13 is provided with a suction cup 105, which can improve the stability of the cylindrical box body 1.

[0031] Furthermore, a slot frame 131 is welded to the top of the leg 13, and the top of the slot frame 131 is welded to the bottom of the cylindrical box body 1, and a turntable 132 is connected to the bottom of the leg 13. The suction cup 105 is arranged at the bottom of the turntable 132. This arrangement enables the cylindrical box body 1 to rotate freely, which is convenient for extracting different test tubes. The turntable 132 is provided with a plurality of connection holes 1321 near the outer periphery, and the top of the suction cup 105 is provided with an integral pile 1051 that is adhesively connected to the connection hole 1321.

[0032] Working principle: control the semiconductor refrigeration plate 2 to be energized, and the refrigeration surface of the semiconductor refrigeration plate 2 provides low temperature to the cylindrical box body 1, and then manually control the limit rod 104 to rotate through the handle 1042, and the two ends of the limit rod 104 are separated from the L-shaped hook plate 12, and the support spring 103 pushes the current pull-out frame 6 to move outward until the rear sealing plate 101 is pressed against the inner wall of the cylindrical box body 1, the window 5 is closed, and the test tube in the extended pull-out frame 6 is in an exposed state, and then the test tube can be taken out by hand. When the test tube needs to be placed, the test tube is inserted into the test tube support ring 7, and the test tube bottom support 8 supports the test tube, and then the handle is manually pressed, the limit rod 104 drives the pull-out frame 6 to be pushed into the cylindrical box body 1, and the test tube is brought into the cylindrical box body 1, and the front sealing plate 9 squeezes the outer wall of the cylindrical box body 1, and then the limit rod 104 is twisted, the L-shaped hook plate 12 hooks the limit rod 104, and the current pull-out frame 6 is closed.

[0033] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. A RNA extraction and purification kit, comprising a cylindrical box body (1), characterized in that: A semiconductor refrigeration plate (2) is arranged at the bottom of the cylindrical box body (1), and a plurality of windows (5) are opened on the outer circumference of the cylindrical box body (1). A pull-out frame (6) is arranged in the window (5), and a test tube support ring (7) and a test tube bottom support (8) are arranged at the top and bottom of the pull-out frame (6), respectively. A front sealing plate (9) and a rear sealing plate (101) which are sealed with the window (5) are arranged at the front and rear sides of the pull-out frame (6), respectively. Both sides of the pull-out frame (6) are in a hollow state.

2. The RNA extraction and purification kit according to claim 1, characterized in that: Slide grooves (51) are provided on both sides of the window (5), and limiting blocks (61) that are slidably matched with the slide grooves (51) are welded on both sides of the drawer frame (6).

3. The RNA extraction and purification kit according to claim 1, characterized in that: A circle of sealing rubber pad (102) is bonded to the opposite sides of the front sealing plate (9) and the rear sealing plate (101); a column (11) is arranged in the middle of the cylindrical box body (1); a support spring (103) is arranged between the column (11) and the rear sealing plate (101); the front side of the front sealing plate (9) is rotatably connected to a limit rod (104); and the outer peripheral wall of the cylindrical box body (1) is welded with L-shaped hook plates (12) located on the upper and lower sides of the front sealing plate (9).

4. The RNA extraction and purification kit according to claim 3, characterized in that: A positioning shaft (91) is welded to the middle of the front side of the front sealing plate (9), and a positioning hole (1041) rotatably connected to the positioning shaft (91) is opened in the middle of the limiting rod (104).

5. The RNA extraction and purification kit according to claim 4, characterized in that: A handle (1042) is welded to the front side of the limiting rod (104).

6. The RNA extraction and purification kit according to claim 3, characterized in that: The bottom of the cylindrical box body (1) is provided with a supporting leg (13), and the bottom of the supporting leg (13) is provided with a suction cup (105).

7. The RNA extraction and purification kit according to claim 6, characterized in that: A slot frame (131) is welded to the top of the supporting leg (13), the top of the slot frame (131) is welded to the bottom of the cylindrical box body (1), the bottom of the supporting leg (13) is connected to a turntable (132), and the suction cup (105) is arranged at the bottom of the turntable (132).

8. The RNA extraction and purification kit according to claim 7, characterized in that: The rotating disk (132) is provided with a plurality of connection holes (1321) near the outer periphery, and the top of the suction cup (105) is provided with an integral pile (1051) which is adhesively connected to the connection holes (1321).

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