Continuous separation device for glutathione production

Abstract

The utility model provides a continuous separation device for glutathione production, which belongs to the technical field of glutathione production and is characterized in that a cleaning component is introduced, so that a user adds raw materials into a cleaning box at the upper end of an equipment main body through a raw material box when using the continuous separation device, and the raw materials are adsorbed by ion exchange resin placed in the cleaning box; then an elution agent is added into the cleaning box through the raw material box, then a driving motor operates to drive a transmission shaft to rotate, and the transmission shaft rotates to drive stirring fan blades to rotate to stir and elute the interior of the cleaning box, so that the contact area between the elution agent and the ion exchange resin is increased; therefore, the dewatering and washing efficiency is improved, the dewatering and washing effect is better, and the problem that dewatering and washing are slow during stock solution is effectively solved. Therefore, the device not only improves the production speed of the glutathione, but also ensures the high-quality output of the glutathione.

Description

Technical Field

[0001] The utility model relates to the technical field of glutathione production, in particular to a continuous separation device used for glutathione production. Background Art

[0002] In biopharmaceuticals and related fields, glutathione plays a key role as an important biological molecule. Glutathione is a tripeptide containing an amine bond and a ketone group. It is composed of amino acids, cysteine ​​and glycine and exists in almost every cell of the body. As a small molecule peptide containing a sulfur group, it has two important physiological effects: antioxidant and integrated detoxification. Antioxidant effect refers to the ability of glutathione to neutralize free radicals in the body and reduce the damage of oxidative stress to cells. This is crucial for maintaining the stability of the intracellular environment, delaying the aging process and preventing a variety of diseases. The integrated detoxification effect is manifested in that glutathione can combine with toxic substances in the body to form a soluble complex, thereby promoting the excretion of toxins from the body and protecting the organism from harmful substances.

[0003] In the production process of glutathione, the design and optimization of continuous separation devices are of great significance for achieving efficient production and reducing production costs. However, the traditional separation device has low production efficiency and slow speed when eluting glutathione, so it is necessary to provide a device with high production efficiency and poor elution effect and low efficiency. Utility Model Content

[0004] In view of the deficiencies of the prior art, the utility model provides a continuous separation device for glutathione production, which solves the problem of low production efficiency of some continuous separation devices for glutathione production in the prior art.

[0005] A continuous separation device for glutathione production, comprising a main mechanism, an auxiliary mechanism and a collection crystallization mechanism, the main mechanism comprising an equipment body and a cleaning component, the upper part of the equipment body is set as a cleaning box, the cleaning component is set at the top of the equipment body, the cleaning component comprises a raw material box, a movable cover, a lower feed port, a driving motor, a cleaning box, a transmission shaft, a stirring fan blade and an electromagnetic valve, the raw material box is set at the upper end of the equipment body, the movable cover is movably set at the upper end of the raw material box, the lower feed port is set at the lower end of the raw material box and is connected to the cleaning box included in the equipment body, the driving motor is set at the middle of the upper end of the equipment body, the transmission shaft is movably installed on the output shaft of the driving motor and is set in the cleaning box, the stirring fan blades are evenly distributed at the left and right ends of the transmission shaft, and the electromagnetic valve is movably installed in the middle of the lower end of the cleaning box.

[0006] Preferably, the auxiliary mechanism includes a filter, a connecting pipe, a storage box, a radiator and a heater, wherein the filter is arranged at the lower end of the solenoid valve, the connecting pipe is arranged at the lower end of the filter and connected to the filter, the storage box is arranged at the lower end of the connecting pipe and connected to the connecting pipe, the radiator is arranged on both sides of the upper end of the storage box, and the heater is arranged on the left and right sides of the discharge pipe and fits the bottom of the storage box. It should be noted that the use of the filter effectively removes the solid impurities and ion exchange resin particles generated during the elution process, improves the purity of the eluent, and thus ensures that the quality of the produced glutathione meets the requirements. The connecting pipe, as a channel for liquid transmission, helps to ensure that the liquid after elution and filtration flows to the storage box. The storage box is set up to store pure glutathione solution in a centralized manner, which is convenient for subsequent processing and collection. At the same time, the raw materials discharged by the heater are heated to achieve a concentration effect, improve the concentration of glutathione, and create more favorable conditions for subsequent crystallization and collection. The radiator realizes the heat dissipation inside the fuselage on the one hand, and can also effectively control the liquid temperature and maintain a suitable temperature.

[0007] Preferably, a discharge pipe is provided at the lower end of the storage box.

[0008] Preferably, the collection crystallization mechanism includes a movable slide rail, a placement box and a collection box, the feed port of the collection box is connected to the discharge pipe, and the collection box is movably arranged in the placement box, and the bottom end of the placement box is movably connected to the movable slide rail arranged on the bottom end of the inner side of the equipment body. The material in the storage box arrives at the collection box, and crystallization is completed in the collection box. Then the movable door is opened, and the placement box is pulled out of the equipment along the movable slide rail, and then the collection box is also taken out, and then the collection box is taken out of the placement box. After the placement box replaces the new collection box, the placement box is placed in the equipment for recycling. Through this recycling process, the production efficiency is effectively improved, and the high-quality production of the crystallized product is ensured. The design of the entire collection crystallization mechanism makes the crystallization and collection process more convenient and efficient, so that sustainable operation is achieved.

[0009] Furthermore, a movable door is provided on the device body corresponding to the position of the placement box, which facilitates opening the movable door and taking out the collection box.

[0010] Preferably, a load-bearing plate is provided at the bottom of the equipment body, and a universal wheel is provided at the lower end of the load-bearing plate, so that the entire device has flexible mobility.

[0011] Preferably, an inspection door is movably provided on the top side of the device body, and a door handle is provided on the inspection door. The inspection door allows operators to easily enter the top part of the device body to perform maintenance and inspection work, such as cleaning the filter, to avoid the filter from being blocked due to long-term use. The filter can be selected as a filter plate.

[0012] Preferably, it also includes an integrated controller, which is arranged on the side of the device body to facilitate the control of the device.

[0013] Compared with the prior art, the utility model has the following beneficial effects:

[0014] The utility model provides a continuous separation device for glutathione production. By introducing a cleaning component, when using the device, the user first adds the raw material into the cleaning box at the upper end of the device body through the raw material box, and the raw material is adsorbed by the ion exchange resin placed in the cleaning box. Then, the de-washing agent is added through the raw material box to reach the cleaning box. Then, the driving motor drives the transmission shaft to rotate, and the rotation of the transmission shaft drives the stirring blade to rotate to stir and elute the cleaning box, thereby increasing the contact area between the de-washing liquid and the ion exchange resin, thereby accelerating the de-washing efficiency and making the de-washing effect better, effectively solving the problem of slow de-washing of the raw liquid. Therefore, the device not only improves the production speed of glutathione, but also ensures the high-quality output of glutathione. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 This is a schematic diagram of the structure of the continuous separation device for glutathione production according to the utility model;

[0016] Figure 2 It is a cross-sectional schematic diagram of the continuous separation device for glutathione production according to the utility model;

[0017] Figure 3 It is a partial enlarged detailed structural diagram of the cleaning component of the utility model;

[0018] Figure 4 It is a schematic diagram of a partially enlarged detailed structure of the auxiliary mechanism of the utility model.

[0019] in:

[0020] 1-main mechanism, 101-equipment body, 102-cleaning assembly, 1021-raw material box, 1022-movable cover, 1023-discharge port, 1024-drive motor, 1025-cleaning box, 1026-transmission shaft, 1027-stirring fan blade, 1028-solenoid valve, 2-auxiliary mechanism, 201-inspection door, 202-door handle, 203-integrated controller, 204-filter, 205-connecting pipe, 206-storage box, 207-radiator, 208-discharge pipe, 209-heater, 3-collection crystallization mechanism, 301-load-bearing plate, 302-universal wheel, 303-movable door, 304-movable slide rail, 305-placement box, 306-collection box, 307-feed port. DETAILED DESCRIPTION

[0021] The embodiments described below are only some embodiments of the utility model, not all embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0022] See also Figure 1 to Figure 4 The present embodiment provides a continuous separation device for glutathione production, comprising a main mechanism 1, an auxiliary mechanism 2 and a collection crystal mechanism 3, wherein the main mechanism 1 comprises an equipment body 101 and a cleaning component 102, wherein the upper portion of the equipment body 101 is provided with a cleaning box 1025, wherein the cleaning component 102 is provided at the top of the equipment body 101, wherein the cleaning component 102 comprises a raw material box 1021, a movable cover 1022, a lower material port 1023, a driving motor 1024, a cleaning box 1025, a transmission shaft 1026, a stirring fan blade 1027 and a solenoid valve 1028, wherein the raw material box 102 1 is arranged at the upper end of the equipment body 101, the movable cover 1022 is movably arranged at the upper end of the raw material box 1021, the discharge port 1023 is arranged at the lower end of the raw material box 1021 and is connected with the cleaning box 1025 included in the equipment body 101, the driving motor 1024 is arranged in the middle of the upper end of the equipment body 101, the transmission shaft 1026 is movably installed on the output shaft of the driving motor 1024 and is arranged in the cleaning box 1025, the stirring blades 1027 are evenly distributed at the left and right ends of the transmission shaft 1026, and the solenoid valve 1028 is movably installed in the middle of the lower end of the cleaning box 1025.

[0023] Combination Figure 4Preferably, the auxiliary mechanism 2 includes a filter 204, a connecting pipe 205, a storage box 206, a radiator 207 and a heater 209, the filter 204 is arranged at the lower end of the solenoid valve 1028, the connecting pipe 205 is arranged at the lower end of the filter 204 and connected to the filter 204, the storage box 206 is arranged at the lower end of the connecting pipe 205 and connected to the connecting pipe 205, the radiator 207 is arranged on both sides of the upper end of the storage box 206, and the heater 209 is arranged on the left and right sides of the discharge pipe 208 and fits the bottom 206 of the storage box. It should be noted that the use of the filter 204 effectively removes the solid impurities and ion exchange resin particles generated during the elution process, improves the purity of the eluent, and thus ensures that the quality of the produced glutathione meets the requirements. The connecting pipe 205 serves as a channel for liquid transmission, which helps to ensure that the eluted and filtered liquid flows to the storage box 206. The storage box 206 is set to store pure glutathione solution in a centralized manner, which is convenient for subsequent processing and collection. At the same time, the raw materials discharged by the heater 209 are heated to achieve a concentration effect, increase the concentration of glutathione, and create more favorable conditions for subsequent crystallization and collection. The radiator 207 realizes the heat dissipation inside the fuselage on the one hand, and can also effectively control the liquid temperature and maintain a suitable temperature. Preferably, a discharge pipe 208 is provided at the lower end of the storage box 206.

[0024] Combination Figure 2 , Figure 3 Preferably, the collection crystallization mechanism 3 includes a movable slide rail 304, a placement box 305 and a collection box 306, the feed port 307 of the collection box 306 is connected to the discharge pipe 208, and the collection box 306 is movably arranged in the placement box 305, and the bottom end of the placement box 305 is movably connected to the movable slide rail 304 arranged on the bottom end of the inner side of the device body 101. The material in the storage box 206 arrives in the collection box 306, and crystallization is completed in the collection box 306. Then the movable door 303 is opened, and the placement box 305 is pulled out of the device along the movable slide rail 304, and then the collection box 306 is also taken out, and then the collection box 306 is taken out from the placement box 305. After the placement box 305 replaces the new collection box 306, the placement box 305 is placed in the device for recycling. Through this recycling process, the production efficiency is effectively improved and the high-quality production of the crystallized product is ensured. The design of the entire collection and crystallization mechanism 3 makes the crystallization and collection process more convenient and efficient, thereby achieving sustainable operation.

[0025] Furthermore, the device body 101 is provided with a movable door 303 at the position corresponding to the placement box 305, which facilitates opening the movable door 303 and taking out the collection box 306. Preferably, a load-bearing plate 301 is provided at the bottom of the device body 101, and a universal wheel 302 is provided at the lower end of the load-bearing plate 301, so that the entire device has flexible mobility.

[0026] Preferably, an inspection door 201 is movably provided on the top side of the device body 101, and a door handle 202 is provided on the inspection door 201. The provision of the inspection door 201 allows the operator to conveniently enter the top part of the device body 101 to perform maintenance and overhaul work, such as cleaning the filter 204, to avoid the filter 204 from being blocked due to long-term use. The filter 204 can be a filter plate. Preferably, an integrated controller 203 is also included, and the integrated controller 203 is provided on the side of the device body 101 to facilitate the control of the device.

[0027] It should be noted that when in use, first, open the movable cover 1022 and pour the raw material into the raw material box 1021. Then, the raw material is introduced into the cleaning box 1025 at the upper end of the equipment body 101 through the discharge port 1023, and the raw material is adsorbed by the ion exchange resin in the cleaning box 1025. Next, the user adds a de-washing agent to the raw material box 1021, and the de-washing agent enters the cleaning box 1025 through the discharge port 1023. Then, the driving motor 1024 is started to rotate the transmission shaft 1026. The movement of the transmission shaft 1026 drives the stirring blade 1027 to rotate, and the material in the cleaning box 1025 is stirred and eluted. After stirring and eluting, the electromagnetic valve 1028 is controlled to open, and the eluted raw material passes through the electromagnetic valve 1028 and is filtered by the filter 204. The connecting pipe 205 guides the filtered raw material to the storage box 206. The raw material is heated by the heater 209 to be concentrated. Then the raw material reaches the collection box 306 through the discharge pipe 208. In the collection box 306, the raw material completes the crystallization process. Thereafter, the user opens the movable door 303, pulls the placement box 305 out of the device through the movable slide rail 304, and takes out the collection box 306. Subsequently, the user can replace the new collection box 306 and put it back into the device to achieve recycling.

[0028] The utility model provides a continuous separation device for glutathione production. By introducing a cleaning component 102, when using, the user first adds the raw material to the cleaning box 1025 at the upper end of the equipment body 101 through the raw material box 1021, and the raw material is adsorbed by the ion exchange resin placed in the cleaning box 1025. Then, the de-washing agent is added through the raw material box 1021 to reach the cleaning box 1025, and then the transmission shaft 1026 is driven to rotate by the operation of the driving motor 1024, and the stirring blade 1027 is driven to rotate by the rotation of the transmission shaft 1026 to stir and elute the cleaning box 1025, so that the contact area between the de-washing liquid and the ion exchange resin is increased, thereby accelerating the de-washing efficiency and making the de-washing effect better, effectively solving the problem of slow de-washing of the raw liquid. Therefore, the device not only improves the production speed of glutathione, but also ensures the high-quality output of glutathione.

[0029] The above disclosures are only several preferred embodiments of the present invention, which certainly cannot be used to limit the scope of rights of the present invention. Therefore, equivalent changes made according to the scope of the patent application of the present invention are still within the scope covered by the present invention.

Claims

1. A continuous separation device for glutathione production, comprising a main mechanism, an auxiliary mechanism and a collection crystal mechanism, characterized in that: The main mechanism includes an equipment body and a cleaning component, the upper part of the equipment body is set as a cleaning box, the cleaning component is set at the top of the equipment body, the cleaning component includes a raw material box, a movable cover, a lower feed port, a driving motor, a cleaning box, a transmission shaft, a stirring fan blade and a solenoid valve, the raw material box is set at the upper end of the equipment body, the movable cover is movably set at the upper end of the raw material box, the lower feed port is set at the lower end of the raw material box and is connected to the cleaning box included in the equipment body, the driving motor is set in the middle of the upper end of the equipment body, and the transmission shaft is movably installed on the output shaft of the driving motor and It is arranged in the cleaning box, the stirring blades are evenly distributed at the left and right ends of the transmission shaft, the solenoid valve is movably installed in the middle of the lower end of the cleaning box, the auxiliary mechanism includes a filter, a connecting pipe, a storage box, a radiator and a heater, the filter is arranged at the lower end of the solenoid valve, the connecting pipe is arranged at the lower end of the filter and connected to the filter, the storage box is arranged at the lower end of the connecting pipe and connected to the connecting pipe, the radiator is arranged on both sides of the upper end of the storage box, and a discharge pipe is arranged at the lower end of the storage box, and the heater is arranged on the left and right sides of the discharge pipe and fits with the bottom of the storage box.

2. The continuous separation device for glutathione production according to claim 1, characterized in that: The crystallization collection mechanism includes a movable slide rail, a placement box and a collection box. The feed port of the collection box is connected to the discharge pipe, and the collection box is movably arranged in the placement box. The bottom end of the placement box is movably connected to the movable slide rail arranged on the bottom end of the inner side of the equipment body.

3. The continuous separation device for glutathione production according to claim 2, characterized in that: The device body is provided with a movable door corresponding to the position of the placement box.

4. The continuous separation device for glutathione production according to claim 1, characterized in that: A load-bearing plate is arranged at the bottom of the equipment body, and a universal wheel is arranged at the lower end of the load-bearing plate.

5. The continuous separation device for glutathione production according to claim 1, characterized in that: An inspection door is movably provided on the top side of the equipment body.

6. The continuous separation device for glutathione production according to claim 5, characterized in that: It also includes an integrated controller, which is arranged on the side of the device body.

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