Animal spinal cord semi-transection injury modeling device
By designing a semi-transverse injury molding device for animal spinal cord including a stent, positioning needle, adjustment mechanism and telescopic mechanism, the problem of the inability to accurately locate and control spinal cord injury in the prior art is solved, and the precise damage to the spinal cord of different experimental animals is achieved, and the accuracy and stability of experimental data are improved.
Patent Information
- Application Number
- CN202421124500.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-22
- Publication Date
- 2025-03-11
- Estimated Expiration
- 2034-05-22
AI Technical Summary
The prior art cannot accurately locate the center position of the spinal cord of experimental animals, the degree of injury is difficult to control, and it cannot be adjusted according to different types of experimental animals, resulting in inaccurate position of spinal cord injury, affecting the accuracy and stability of experimental data.
An animal spinal cord semi-transverse injury molding device is designed, including a stent, a positioning needle, an adjustment mechanism and a telescopic mechanism. By setting a positioning needle on one side of the bracket and an adjustment mechanism for the positioning needle is provided at the upper end of the bracket. The positioning needle can move freely in the through groove and movable groove, and is fixed at a limit through the reinforcement sleeve to ensure the accurate position of the positioning needle. The telescopic mechanism includes a micro motor, a micro screw and a resistance shaft, which can realize the rotation and expansion of the cutting edge and adapt to the spinal cord structure of different experimental animals.
Through this modeling device, the center position of the spinal cord of the experimental animal can be accurately positioned, the degree of damage can be controlled, and different types of experimental animals can be adapted to, improving the accuracy and stability of the experimental data.
Smart Images
Figure CN222584710U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of basic medical research, in particular to a modeling device for semi-transverse injury of animal spinal cord. Background Art
[0002] Animal hemisection spinal cord injury is a common experimental model, which is often used to study nerve regeneration, injury treatment and rehabilitation. This model involves surgical operation to create a hemisection injury on the animal's spinal cord, that is, the injury will transect the longitudinal conduction pathway of half of the spinal cord, but the other half will remain. The animal hemisection spinal cord injury model provides an important platform for the study of the pathogenesis of spinal cord injury and injury repair.
[0003] In the prior art, in order to cause hemi-transection injury to the spinal cord of experimental animals, an animal spinal cord injury modeler is usually used to strike or cut the spine of the experimental animal, thereby forming a hemi-transection injury to the spinal cord. However, most modelers used for hemi-transection injury to the animal spinal cord (surgical blades and scissors, etc.) cannot accurately locate the median position of the spinal cord, the degree of injury is difficult to control, and the modeler cannot be adjusted according to different types of experimental animals. This often leads to inaccurate positioning of the spinal cord injury of the experimental animals, thereby affecting the accuracy and stability of the experimental data. Utility Model Content
[0004] The utility model aims at the deficiencies of the prior art and provides the following technical solutions:
[0005] A modeling device for semi-transverse injury of animal spinal cord, comprising a bracket and a positioning pin arranged on one side of the bracket, wherein the upper end of the bracket is provided with a through slot penetrating the inside thereof, the positioning pin is movably inserted in the through slot, the upper end of the bracket is provided with an adjustment mechanism for the positioning pin, the lower end of the bracket is provided with a cutting blade, and a telescopic mechanism is provided between the bracket and the cutting blade;
[0006] The adjustment mechanism includes a fixing part arranged at the upper end of the bracket, the fixing part is welded and fixed to the inner upper end of the bracket, a movable groove is opened inside the fixing part, the fixing part is located directly below the through groove, and the movable groove corresponds to the through groove, the positioning pin passes through the through groove and the movable groove in sequence from top to bottom, a limiting head is welded and fixed at the top end of the positioning pin, the limiting head is located above the through groove, a reinforcement sleeve is screwed and installed on the outer surface of the positioning pin, and the reinforcement sleeve is located directly below the fixing part.
[0007] As an improvement of the above technical solution, the bracket is in an inverted "L" shape.
[0008] As an improvement of the above technical solution, the outer surface of the upper end of the positioning pin is provided with a thread, and the interior of the reinforcement sleeve is provided with a thread groove that matches the thread on the outer surface of the positioning pin.
[0009] As an improvement of the above technical solution, the telescopic mechanism includes a connecting plate that is movably inserted into the inside of the bracket, a groove is opened at the inner lower end of the bracket, the connecting plate is arranged inside the groove, a resistance shaft 1 is installed in the middle position of the connecting plate, the lower end of the connecting plate is rotatably connected to the cutting blade through a resistance shaft 2, a movable part is fixedly installed on one side of the outer surface of the connecting plate, a micro screw is screwed inside the movable part, a micro motor is fixedly installed on the inner side of the lower end of the bracket, and the output shaft of the micro motor is fixedly connected to the upper end of the micro screw.
[0010] As an improvement of the above technical solution, a threaded hole adapted to the micro screw is provided inside the movable part, and the micro screw is located outside the connecting plate.
[0011] As an improvement of the above technical solution, a placement groove is provided at the bottom of the bracket, and the placement groove corresponds to and fits the position of the cutting blade.
[0012] Beneficial effects of the utility model:
[0013] A positioning needle is arranged on one side of the bracket, and a positioning needle adjustment mechanism is arranged at the upper end of the bracket. Under the cooperation of the fixing part, the movable groove, the reinforcement sleeve and the limit head in the adjustment mechanism, the positioning needle can move freely in the through groove and the movable groove to adjust the orientation of the positioning needle, and after adjusting the position of the positioning needle, the positioning needle is limited and fixed by the reinforcement sleeve, thereby increasing the convenience of adjusting the positioning needle and increasing the stability after adjustment, so as to facilitate the use of the positioning needle in the mid-position positioning of the spinal cord tissue of different experimental animals, and further facilitate the semi-transverse injury of the spinal cord of different experimental animals. BRIEF DESCRIPTION OF THE DRAWINGS
[0014] Figure 1 It is a three-dimensional structural diagram of the utility model;
[0015] Figure 2 It is a side structural diagram of the utility model;
[0016] Figure 3 This is a bottom structural diagram of the bracket in the utility model;
[0017] Figure 4 For this utility model Figure 2 Enlarged structural diagram of point A in the middle.
[0018] Figure numerals: 1, bracket; 101, through slot; 102, placement slot; 2, positioning pin; 201, limit head; 202, reinforcement sleeve; 3, fixing piece; 301, movable slot; 4, cutting blade; 401, connecting plate; 402, movable piece; 403, micro screw; 404, micro motor; 405, groove; 406, resistance shaft one; 407, resistance shaft two. DETAILED DESCRIPTION
[0019] In order to make the purpose, technical solution and advantages of the utility model more clear, the utility model is further described in detail below. It should be understood that the specific embodiments described here are only used to explain the utility model, and are not used to limit the utility model.
[0020] See also Figure 1-4 The utility model provides a technical solution: a modeling device for semi-transverse injury of animal spinal cord, comprising a bracket 1 and a positioning pin 2 arranged on one side of the bracket 1, a through slot 101 penetrating the inside of the bracket 1 is provided at the upper end of the bracket 1, the positioning pin 2 is movably inserted in the inside of the through slot 101, an adjustment mechanism for the positioning pin 2 is provided at the upper end of the bracket 1, a cutting blade 4 is provided at the lower end of the bracket 1, and a telescopic mechanism is provided between the bracket 1 and the cutting blade 4;
[0021] The adjustment mechanism includes a fixing part 3 arranged at the upper end of the bracket 1, the fixing part 3 is welded and fixed to the inner upper end of the bracket 1, a movable groove 301 is opened inside the fixing part 3, the fixing part 3 is located directly below the through groove 101, and the movable groove 301 corresponds to the through groove 101, the positioning pin 2 passes through the through groove 101 and the movable groove 301 from top to bottom in sequence, a limiting head 201 is welded and fixed at the top end of the positioning pin 2, the limiting head 201 is located above the through groove 101, a reinforcement sleeve 202 is screwed and installed on the outer surface of the positioning pin 2, and the reinforcement sleeve 202 is located directly below the fixing part 3.
[0022] In the present embodiment, a positioning needle 2 is provided on one side of the bracket 1, and an adjustment mechanism for the positioning needle 2 is provided at the upper end of the bracket 1. With the cooperation of the fixing part 3, the movable groove 301, the reinforcing sleeve 202 and the limiting head 201 in the adjusting mechanism, the positioning needle 2 can move freely in the through groove 101 and the movable groove 301 to adjust the orientation of the positioning needle 2. After adjusting the position of the positioning needle 2, the positioning needle 2 is limited and fixed by the reinforcing sleeve 202, thereby increasing the convenience of adjusting the positioning needle 2 and increasing the stability after adjustment, so as to facilitate the use of the positioning needle 2 in different positions, and further facilitate the overall device to cause semi-transverse injury to the spinal cord of experimental animals.
[0023] Specifically, the bracket 1 is in an inverted "L" shape.
[0024] Specifically, the outer surface of the upper end of the positioning pin 2 is provided with a thread, and the interior of the reinforcing sleeve 202 is provided with a thread groove that matches the thread on the outer surface of the positioning pin 2 .
[0025] Specifically, the telescopic mechanism includes a connecting plate 401 movably inserted into the inside of the bracket 1, a groove 405 is provided at the inner lower end of the bracket 1, the connecting plate 401 is arranged inside the groove 405, a resistance shaft 1 406 is installed at the middle position of the connecting plate 401, the lower end of the connecting plate 401 is rotatably connected to the cutting blade 4 through a resistance shaft 2 407, a movable part 402 is fixedly installed on one side of the outer surface of the connecting plate 401, a micro screw 403 is screwed inside the movable part 402, a micro motor 404 is fixedly installed on the inner side of the lower end of the bracket 1, the output shaft of the micro motor 404 is fixedly connected to the upper end of the micro screw 403, a threaded hole matched with the micro screw 403 is provided inside the movable part 402, and the micro screw 403 is located on the outer side of the connecting plate 401, and a mounting groove 102 is provided at the bottom of the bracket 1, and the mounting groove 102 corresponds to and matches the position of the cutting blade 4.
[0026] In this embodiment, a cutting blade 4 is arranged at the bottom of the bracket 1, and a telescopic mechanism is arranged between the bracket 1 and the cutting blade 4. In the telescopic mechanism, the connecting plate 401, the movable part 402, the micro screw 403, and the micro motor 404 cooperate with each other, and the micro screw 403 is driven by the micro motor 404 to rotate, and at the same time, the movable part 402 and the connecting plate 401 are driven to move upward or downward. A resistance shaft 2 407 is arranged between the connecting plate 401 and the cutting blade 4, which can realize the rotation of the cutting blade 4, so that the blade direction of the cutting blade 4 is perpendicular to the bracket 1, so that the cutting blade 4 can be convenient for cutting. At the same time, a placement groove 102 is arranged at the bottom of the bracket 1, which can facilitate the storage of the cutting blade 4. When the device is not in use, the experimenter is prevented from being cut by the cutting blade 4.
[0027] The above embodiments are only used to illustrate the technical solution of the present invention, but not to limit it.
Claims
1. A modeling device for semi-transverse injury of animal spinal cord, comprising a support (1) and a positioning needle (2) arranged on one side of the support (1), characterized in that: The upper end of the support (1) is provided with a through slot (101) penetrating the interior thereof, the positioning needle (2) is movably inserted into the interior of the through slot (101), the upper end of the support (1) is provided with an adjustment mechanism for the positioning needle (2), the lower end of the support (1) is provided with a cutting blade (4), and a telescopic mechanism is provided between the support (1) and the cutting blade (4); The adjustment mechanism comprises a fixing member (3) arranged at the upper end of the bracket (1), the fixing member (3) being welded and fixed to the inner upper end of the bracket (1), a movable groove (301) being provided inside the fixing member (3), the fixing member (3) being located directly below the through groove (101), and the movable groove (301) and the through groove (101) corresponding to each other, the positioning pin (2) passing through the through groove (101) and the movable groove (301) in sequence from top to bottom, a limiting head (201) being welded and fixed at the top end of the positioning pin (2), the limiting head (201) being located above the through groove (101), a reinforcing sleeve (202) being screwed and installed on the outer surface of the positioning pin (2), and the reinforcing sleeve (202) being located directly below the fixing member (3).
2. The animal spinal cord hemisection injury modeler according to claim 1, characterized in that: The bracket (1) is in an inverted "L" shape.
3. The animal spinal cord hemisection injury modeler according to claim 1, characterized in that: The upper outer surface of the positioning pin (2) is provided with a thread, and the interior of the reinforcement sleeve (202) is provided with a thread groove that matches the thread on the outer surface of the positioning pin (2).
4. The animal spinal cord hemisection injury modeler according to claim 1, characterized in that: The telescopic mechanism comprises a connecting plate (401) movably inserted into the interior of the bracket (1); a groove (405) is provided at the inner lower end of the bracket (1); the connecting plate (401) is arranged inside the groove (405); a resistance shaft (406) is installed at the middle position of the connecting plate (401); the lower end of the connecting plate (401) is rotatably connected to the cutting blade (4) via a resistance shaft (407); a movable part (402) is fixedly installed on one side of the outer surface of the connecting plate (401); a micro screw (403) is screwedly installed inside the movable part (402); a micro motor (404) is fixedly installed on the inner side of the lower end of the bracket (1); and the output shaft of the micro motor (404) is fixedly connected to the upper end of the micro screw (403).
5. The animal spinal cord hemisection injury modeler according to claim 4, characterized in that: A threaded hole matched with a micro screw rod (403) is provided inside the movable part (402), and the micro screw rod (403) is located outside the connecting plate (401).
6. The animal spinal cord hemisection injury modeler according to claim 1, characterized in that: The bottom of the bracket (1) is provided with a placement groove (102), and the placement groove (102) corresponds to and fits the position of the cutting blade (4).