Liquid medicine extraction device for biopharmacy

Abstract

The utility model provides a biopharmacy liquid medicine extraction device, including: box and extraction cylinder, the bottom of said box is movably connected with the rotating column through the sealing bearing, the lower surface of box is fixedly connected with the main motor, the main motor output shaft is fixedly connected with the rotating column through the connecting piece, and the upper surface of rotating column is fixedly connected with the extraction cylinder, the outer side surface of the upper end of the extraction cylinder is fixedly connected with a positioning ring, the positioning ring is slidably connected into a positioning groove formed in a limiting ring, the outer side surface of the limiting ring is symmetrically connected with fixing plates, and the ends, away from the limiting ring, of the fixing plates are fixedly connected with the inner side surface of the box body. Through cooperation of the extraction barrel, the rotating column, the air cylinder, the pressing plate, the stirring plate and the main motor, the extraction device can conduct corresponding medicine smashing treatment on medicinal materials in the extraction device, liquid medicine left in the medicinal materials can be correspondingly extruded out through extrusion, and therefore the extraction effect of the extraction device is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of extraction, in particular to a drug liquid extraction device for biopharmaceuticals. Background Art

[0002] In the process of biopharmaceuticals, the effective components of medicinal materials need to be extracted accordingly. Extraction refers to a method in which the compounds are transferred from one solvent to another solvent by utilizing the difference in solubility or distribution coefficient of the compounds in two immiscible or slightly soluble solvents. After repeated extraction, most of the compounds are extracted. The existing medicinal material extraction device is mainly composed of an extraction tank, a crushing device, a heating device, a feed port, a liquid discharge port, and a filtering device. When working, the medicinal materials are placed in the extraction tank, first crushed, and then heated with water. Generally, a high-temperature extraction method is adopted to dissolve the effective substances in the medicinal materials in water by high temperature, and then the medicinal materials are filtered and the liquid is collected; however, the existing medicinal material extraction device cannot guarantee the complete dissolution of the effective components during the extraction process, and the extract is also prone to uneven mixing, which will inevitably affect the extraction quality. In order to fully extract, some extraction operations will first pound the medicine in the pounding pot, and then transport the treated medicinal materials to the extraction site for extraction. However, the intermediate transportation time is long and the degree of drug oxidation is large, which is not conducive to extraction and will also reduce the quality of extraction. Utility Model Content

[0003] In order to overcome the defects of the prior art, a biopharmaceutical liquid extraction device is now provided to solve the problems raised in the above background technology.

[0004] To achieve the above-mentioned purpose, a biopharmaceutical liquid extraction device is provided, comprising: a housing and an extraction cylinder, wherein the bottom of the housing is movably connected to a rotating column via a sealed bearing, and the lower surface of the housing is fixedly connected to a main motor, the output shaft of the main motor is fixedly connected to the rotating column via a connecting piece, and the upper surface of the rotating column is fixedly connected to the extraction cylinder, and the side of the rotating column is symmetrically connected to a stirring plate, while the bottom of the housing is fixedly connected to an intelligent heater, the top of the housing is fixedly connected to a guide plate, and the upper surface of the housing is fixedly connected to a cylinder, and the multi-stage telescopic rods of the cylinder are movably connected to a pressure plate via a bearing, and the outer side surface of the upper end of the extraction cylinder is fixedly connected to a positioning ring, the positioning ring is slidably connected to a positioning groove provided in a limit ring, and the outer side surface of the limit ring is symmetrically connected to a fixing plate, and the end of the fixing plate away from the limit ring is fixedly connected to the inner side surface of the housing.

[0005] Preferably, the rotating column is an overall cylindrical structure, and the axial cross-section of the rotating column is a T-shaped structure, and the outer arc surface of the upper end of the rotating column is circumferentially surrounded by multiple sets of stirring plates fixedly connected at equal intervals. At the same time, the stirring plates are an overall rectangular structure, and the cross-section of the stirring plates is a parallelogram structure.

[0006] Preferably, the extraction cylinder has a cylindrical structure, a plurality of filter holes are evenly arranged on the outer arc surface of the extraction cylinder, and a plurality of protrusions are evenly fixedly connected to the bottom of the extraction cylinder, the protrusions have a hemispherical structure, and the sizes of the inner cavity of the extraction cylinder and the pressing plate are matched, and a plurality of protrusions are evenly fixedly connected to the lower surface of the pressing plate.

[0007] Preferably, the upper end of the outer arc surface of the extraction cylinder is fixedly connected to a positioning ring, the positioning ring is annular in structure, and the outer arc surface of the positioning ring is provided with a plurality of movable grooves at equal intervals along the circumferential direction, and the balls are movably connected in the movable grooves.

[0008] Preferably, the limiting ring is in a circular ring structure, the inner diameter of the limiting ring is matched with the outer diameter of the extraction tube, and the positioning groove formed on the inner arc surface of the limiting ring is matched with the size of the positioning ring, and at the same time, a slide groove is formed on the side of the positioning groove corresponding to the position of the ball, and the cross-section of the slide groove is in an arc-shaped structure.

[0009] Preferably, the outer arc surface of the limiting ring is circumferentially connected to multiple groups of fixing plates at equal intervals, and the multiple groups of fixing plates are all T-shaped structures, and the axial cross-section formed by the combination of the limiting ring and the positioning groove is a concave structure.

[0010] Preferably, the guide plate is cylindrical in structure, and the size of the upper opening of the guide plate is larger than that of the lower opening, while the size of the lower opening of the guide plate is matched with the size of the inner cavity of the extraction tube, and the feed port opened on the upper surface of the box body is connected to the upper opening of the guide plate.

[0011] Compared with the prior art, the beneficial effects of the utility model are as follows: through the cooperation of the cylinder, the pressing plate and the extraction tube, the medicinal materials can be subjected to the corresponding pounding treatment in the extraction tube, and then after the medicinal materials are processed, the corresponding extraction treatment can be quickly carried out, effectively reducing the probability of the medicine being oxidized, and then being able to assist in improving the quality of the extraction, and at the same time, through the cooperation of the main motor, the rotating column, the stirring plate, the cylinder and the pressing plate, the extracting liquid can be fully mixed with the effective ingredients in the medicinal materials, thereby improving the extraction efficiency of the extracting liquid for the medicine, and the cooperation of the pressing plate and the extraction tube can perform the corresponding extrusion treatment on the medicinal materials remaining in the extraction tube, thereby squeezing out the residual medicinal liquid in the medicinal materials and improving the extraction efficiency of the medicinal materials. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 It is a front view schematic diagram of an embodiment of the utility model.

[0013] Figure 2 This is a schematic diagram of the pressure plate resetting embodiment of the utility model.

[0014] Figure 3 It is a top view schematic diagram of an embodiment of the utility model.

[0015] Figure 4For the utility model embodiment Figure 1 An enlarged schematic diagram of point A.

[0016] In the figure: 1. main motor; 2. rotating column; 3. intelligent heater; 4. box; 5. stirring plate; 6. extraction cylinder; 7. limit ring; 8. fixing plate; 9. pressing plate; 10. guide plate; 11. cylinder; 12. ball; 13. positioning ring. DETAILED DESCRIPTION

[0017] Reference Figures 1 to 4 As shown, the utility model provides a biopharmaceutical liquid extraction device, comprising: a box body 4 and an extraction cylinder 6, the bottom of the box body 4 is movably connected to the rotating column 2 through a sealed bearing, and the lower surface of the box body 4 is fixedly connected to the main motor 1, the output shaft of the main motor 1 is fixedly connected to the rotating column 2 through a connecting piece, and the upper surface of the rotating column 2 is fixedly connected to the extraction cylinder 6, and the side of the rotating column 2 is symmetrically connected to the stirring plate 5, while the bottom of the box body 4 is fixedly connected to the intelligent heater 3, the top of the box body 4 is fixedly connected to the guide plate 10, and the upper surface of the box body 4 is fixedly connected to the cylinder 11, the multi-stage telescopic rod of the cylinder 11 is movably connected to the pressing plate 9 through a bearing, the outer side surface of the upper end of the extraction cylinder 6 is fixedly connected to the positioning ring 13, the positioning ring 13 is slidably connected to the positioning groove opened by the limit ring 7, and the outer side surface of the limit ring 7 is symmetrically connected to the fixing plate 8, and the end of the fixing plate 8 away from the limit ring 7 is fixedly connected to the inner side surface of the box body 4.

[0018] In this embodiment, in the process of biopharmaceuticals, it is necessary to perform corresponding extraction treatment on the medicinal materials, so the medicinal materials are first put into the box body 4 through the feed port, and the medicinal materials will fall into the extraction cylinder 6 under the guidance of the guide plate 10, and then the switch of the cylinder 11 is started, and the multi-stage telescopic rod of the cylinder 11 pushes the pressing plate 9 to move downward periodically, so that the pressing plate 9 can extend into the extraction cylinder 6, and under the mutual cooperation of the pressing plate 9 and the extraction cylinder 6, the medicinal materials in the extraction cylinder 6 can be subjected to corresponding medicine pounding treatment. After the medicinal materials are processed, the pressing plate 9 is reset under the drive of the cylinder 11, and the extractant is injected into the box body 4 through the feed port, and the cylinder 11 is started again, so that the pressing plate 9 keeps the state of closing the opening of the extraction cylinder 6, and then the main motor 1 and The intelligent heater 3 is switched on and off, and the output shaft of the main motor 1 drives the rotating column 2 to rotate through the connecting piece, and the rotating column 2 drives the fixedly connected stirring plate 5 and the extraction cylinder 6 to rotate synchronously, wherein the intelligent heater 3 is a common brand model on the market, and the stirring plate 5 can stir the extractant so that the extractant can fully contact with the medicinal materials, ensuring that the effective ingredients in the medicinal materials can be evenly mixed in the extractant, and then the valve of the drain pipe is opened, the extract can be discharged from the drain pipe, and the switch of the cylinder 11 is started, and the cylinder 11 pushes the pressing plate 9 downward, so that the pressing plate 9 can perform corresponding extrusion treatment on the residual medicinal materials in the extraction cylinder 6, ensuring that the residual liquid in the medicinal materials can be squeezed out smoothly, thereby enhancing the extraction effect of the device.

[0019] As a preferred embodiment, the rotating column 2 is an overall cylindrical structure, and the axial cross-section of the rotating column 2 is a T-shaped structure, and the outer arc surface of the upper end of the rotating column 2 is circumferentially surrounded by a plurality of groups of stirring plates 5 fixedly connected at equal intervals, and the stirring plates 5 are an overall rectangular structure, and the cross-section of the stirring plates 5 is a parallelogram structure.

[0020] In this embodiment, if Figure 1 and Figure 3 The structural setting of the rotating column 2 can enhance the stability of the extraction cylinder 6 when it rotates in the box 4. At the same time, the setting of the stirring plate 5 can stir the extractant in the box 4 accordingly, ensuring that the extractant and the medicinal materials can fully contact, avoiding the effective ingredients of the medicinal materials in some areas of the extractant being too high, and improving the extraction efficiency of the extractant.

[0021] As a preferred embodiment, the extraction cylinder 6 has a cylindrical structure, and a plurality of filter holes are evenly arranged on the outer arc surface of the extraction cylinder 6. A plurality of protrusions are evenly fixedly connected to the bottom of the extraction cylinder 6, and the protrusions have a hemispherical structure. At the same time, the sizes of the inner cavity of the extraction cylinder 6 and the pressing plate 9 are matched, and a plurality of protrusions are evenly fixedly connected to the lower surface of the pressing plate 9.

[0022] In this embodiment, if Figure 1 and Figure 2 The filter holes provided in the extraction cylinder 6 enable the rotating extraction cylinder 6 to perform corresponding solid-liquid separation on the internal medicinal materials and the extract, thereby helping to improve the extraction efficiency of the device. At the same time, the setting of the protrusions can help to enhance the pounding effect between the extraction cylinder 6 and the pressing plate 9, reduce the difficulty of extracting the medicinal materials, and the pressing plate 9 is movably connected to the cylinder 11 through the bearing, so the pressing plate 9 can rotate with the extraction cylinder 6.

[0023] As a preferred embodiment, the upper end of the outer arc surface of the extraction cylinder 6 is fixedly connected to the positioning ring 13, the positioning ring 13 is a circular ring structure, and the outer arc surface of the positioning ring 13 is circumferentially arranged with multiple groups of movable grooves at equal intervals, and the ball 12 is movably connected in the movable groove.

[0024] In this embodiment, if Figure 3 and Figure 4 The arrangement of the ball 12 can help reduce the friction resistance encountered by the positioning ring 13 when it rotates in the positioning groove. The arrangement of the positioning ring 13 can enhance the stability of the upper end of the extraction cylinder 6 when the extraction cylinder 6 rotates, and can reduce the probability of the extraction cylinder 6 being accidentally driven by the pressing plate 9, thereby ensuring the stability of the installation of the extraction cylinder 6.

[0025] As a preferred embodiment, the limiting ring 7 is in a circular ring structure, the inner diameter of the limiting ring 7 is matched with the outer diameter of the extraction tube 6, and the positioning groove formed on the inner arc surface of the limiting ring 7 is matched with the size of the positioning ring 13, and at the same time, a slide groove is formed on the side of the positioning groove corresponding to the position of the ball 12, and the cross-section of the slide groove is in an arc-shaped structure.

[0026] In this embodiment, if Figure 3 and Figure 4 The arc surface of the slide groove fits with the surface of the ball 12, which can increase the force-bearing area of ​​the ball 12, thereby effectively reducing the probability of wear of the ball 12. At the same time, the setting of the limit ring 7 can help enhance the stability of the extraction cylinder 6 during rotation.

[0027] As a preferred embodiment, the outer arc surface of the limit ring 7 is circumferentially surrounded by multiple groups of fixed plates 8 with equal intervals, and the multiple groups of fixed plates 8 are all T-shaped structures, and the axial cross-section formed by the combination of the limit ring 7 and the positioning groove is a concave structure.

[0028] In this embodiment, if Figure 1 and Figure 3 The setting of the fixing plate 8 enables the limiting ring 7 to be stably fixedly connected to the inside of the box body 4, thereby enhancing the limiting effect of the limiting ring 7 on the upper end of the extraction cylinder 6.

[0029] As a preferred embodiment, the guide plate 10 has a cylindrical structure, and the size of the upper opening of the guide plate 10 is larger than the size of the lower opening, and the size of the lower opening of the guide plate 10 is compatible with the size of the inner cavity of the extraction tube 6. At the same time, the feed port opened on the upper surface of the box body 4 is connected to the upper opening of the guide plate 10.

[0030] In this embodiment, if Figure 1 and Figure 2 The structural setting of the guide plate 10 allows the medicinal materials put into the box body 4 to automatically fall into the extraction cylinder 6, thereby preventing the medicinal materials from being scattered inside the box body 4. This can not only improve the extraction efficiency of the medicinal materials by the device, but also help reduce the difficulty of subsequent cleaning. The box body 4 is composed of a main body and a top cover, which is convenient for subsequent cleaning.

[0031] The biopharmaceutical liquid extraction device of the utility model cooperates with the extraction cylinder 6, the rotating column 2, the cylinder 11, the pressing plate 9, the stirring plate 5 and the main motor 1, so that the extraction device can perform corresponding pounding treatment on the internal medicinal materials, and can also squeeze out the residual liquid medicine in the medicinal materials, thereby improving the extraction effect of the extraction device, and through the rotation of the extraction cylinder 6, it can assist in improving the solid-liquid separation efficiency of the extraction liquid.

Claims

1. A biopharmaceutical liquid extraction device, comprising: A housing (4) and an extraction cylinder (6), characterized in that: the bottom of the housing (4) is movably connected to the rotating column (2) via a sealed bearing, and the bottom surface of the housing (4) is fixedly connected to the main motor (1), the output shaft of the main motor (1) is fixedly connected to the rotating column (2) via a connecting piece, and the upper surface of the rotating column (2) is fixedly connected to the extraction cylinder (6), and the side of the rotating column (2) is symmetrically connected to the stirring plate (5), and at the same time, the bottom of the housing (4) is fixedly connected to the intelligent heater (3), the top of the housing (4) is fixedly connected to the guide plate (10), and the upper surface of the housing (4) is fixedly connected to the cylinder (11), and the multi-stage telescopic rod of the cylinder (11) is movably connected to the pressure plate (9) via a bearing, and the outer side surface of the upper end of the extraction cylinder (6) is fixedly connected to the positioning ring (13), the positioning ring (13) is slidably connected to the positioning groove opened by the limit ring (7), and the outer side surface of the limit ring (7) is symmetrically connected to the fixing plate (8), and the end of the fixing plate (8) away from the limit ring (7) is fixedly connected to the inner side surface of the housing (4).

2. A biopharmaceutical liquid extraction device according to claim 1, characterized in that: The rotating column (2) is in an overall cylindrical structure, while the axial cross section of the rotating column (2) is in a T-shaped structure, and the outer arc surface of the upper end of the rotating column (2) surrounds a plurality of groups of stirring plates (5) fixedly connected at equal intervals along the circumferential direction, while the stirring plates (5) are in an overall rectangular structure, while the cross section of the stirring plates (5) is in a parallelogram structure.

3. A biopharmaceutical liquid extraction device according to claim 1, characterized in that: The extraction cylinder (6) has a cylindrical structure, the outer arc surface of the extraction cylinder (6) is evenly provided with a plurality of groups of filter holes, and the bottom of the extraction cylinder (6) is evenly fixedly connected with a plurality of groups of protrusions, the protrusions having a hemispherical structure, and the inner cavity of the extraction cylinder (6) and the pressing plate (9) have matching sizes, and the lower surface of the pressing plate (9) is evenly fixedly connected with the plurality of groups of protrusions.

4. The biopharmaceutical liquid extraction device according to claim 1, characterized in that: The upper end of the outer arc surface of the extraction cylinder (6) is fixedly connected to a positioning ring (13), the positioning ring (13) is in a circular ring structure, and the outer arc surface of the positioning ring (13) is provided with a plurality of groups of movable grooves at equal intervals along the circumferential direction, and the balls (12) are movably connected in the movable grooves.

5. The biopharmaceutical liquid extraction device according to claim 1, characterized in that: The limiting ring (7) is in the form of a circular ring structure, the inner diameter of the limiting ring (7) is matched to the outer diameter of the extraction tube (6), and the positioning groove formed on the inner arc surface of the limiting ring (7) is matched to the size of the positioning ring (13), and a slide groove is formed on the side of the positioning groove corresponding to the position of the ball (12), and the cross section of the slide groove is in the form of an arc surface.

6. The biopharmaceutical liquid extraction device according to claim 1, characterized in that: The outer arc surface of the limiting ring (7) is circumferentially connected to a plurality of fixed plates (8) at equal intervals, and the plurality of fixed plates (8) are all in a T-shaped structure, and the axial cross-section formed by the limiting ring (7) and the positioning groove combined together is in a concave-shaped structure.

7. The biopharmaceutical liquid extraction device according to claim 1, characterized in that: The guide plate (10) is of cylindrical structure, and the size of the opening at the upper end of the guide plate (10) is larger than the size of the opening at the lower end, while the size of the opening at the lower end of the guide plate (10) matches the size of the inner cavity of the extraction cylinder (6), and the feed port opened on the upper surface of the box body (4) is connected to the upper end opening of the guide plate (10).

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