The invention belongs to the field of preparation of medical materials, and particularly relates to a preparation method of medical-grade high-purity
lithium carbonate, which comprises the following steps: carrying out replacement reaction on
metal lithium and deionized water to prepare a
lithium hydroxide solution; introducing
carbon dioxide gas into the
lithium hydroxide solution, carrying out
carbonization treatment, controlling the pH at the end point of the
carbonization reaction to be 8-10.5, and then carrying out
solid-liquid separation treatment to obtain a
lithium bicarbonate solution; carrying out heat preservation treatment on the
lithium bicarbonate solution at the temperature T and the pressure P, and separating to obtain pharmaceutical-grade high-purity
lithium carbonate; the temperature T ranges from 90 DEG C to 98 DEG C, and the P ranges from 0.01 Mpa to 0.09 Mpa. According to the method,
lithium carbonate is synthesized by utilizing a
reaction mechanism of replacement-
carbonization and
thermal insulation transformation treatment, and on the basis, the combination of the pH value of carbonization and the temperature T and pressure P of
thermal insulation treatment is further matched, so that the
nucleation behavior of
lithium carbonate can be accidentally controlled, the
nucleation wrapping of impurities is reduced, and the purity of lithium
carbonate is improved. Therefore, lithium
carbonate which meets medical application requirements and has excellent particle size uniformity can be prepared with high direct yield based on a simple means.