Oligopeptide enzymolysis reaction device

By designing an oligopeptidase enzymatic reaction device that can simultaneously complete pulverization, enzymatic decomposition and separation, the existing device has solved the problems of complex structure and troublesome operation, and improved the reaction efficiency and continuity.

CN222613353UActive Publication Date: 2025-03-14GUOZHEN PEPTIDE (DALIAN) BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202323350698.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2023-12-09
Publication Date
2025-03-14
Estimated Expiration
2033-12-09

AI Technical Summary

Technical Problem

The existing oligopeptidase reaction device has complex structure and troublesome operation, resulting in low reaction efficiency.

Method used

A oligopeptidase enzyme-removing reaction device is designed to realize the crushing, enzymatic dissolution and separation of substrates through a power device, and the meshing of the active bevel gear and the driven bevel gear are used to transmit power, so as to achieve stirring and centrifugal separation.

Benefits of technology

The device structure is simplified, the continuity and efficiency of reactions are improved, and the operation complexity is reduced.

✦ Generated by Eureka AI based on patent content.

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    Figure CN222613353U_ABST
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Abstract

The utility model discloses an oligopeptide enzymolysis reaction device and belongs to the technical field of oligopeptide enzymolysis. Comprising a supporting frame, and a reaction box is fixedly arranged on the supporting frame; a crushing box is fixedly arranged on the side wall of the reaction box, and the crushing box is communicated with the reaction box through a connecting pipe; a motor is arranged on the side wall of the crushing box, a crushing shaft is fixedly connected to an output shaft of the motor, and the crushing shaft extends into the reaction box; a driving bevel gear located in the reaction box is fixedly arranged on the crushing shaft; a stirring shaft is rotationally arranged in the reaction box, and a driven bevel gear meshed with the driving bevel gear is fixedly connected to the stirring shaft; a centrifugal barrel positioned below the reaction box is rotationally arranged in the support frame, and is fixedly connected with the stirring shaft. According to the oligopeptide enzymolysis reaction device, only one power device is arranged, crushing, enzymolysis and separation of a substrate can be completed at the same time through one power device, and the problems that an existing oligopeptide enzymolysis reaction device is complex in structure and troublesome to operate can be solved.
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Description

Technical Field

[0001] The utility model provides an oligopeptide enzymolysis reaction device, belonging to the technical field of oligopeptide enzymolysis. Background Art

[0002] In the field of oligopeptide technology, enzymatic hydrolysis of oligopeptides is often required in order to decompose them into smaller peptides or amino acids. Certain oligopeptides have specific biological activities. When oligopeptides are hydrolyzed, they can release these biologically active peptides to exert their corresponding functions. At the same time, peptides of different lengths may have different activities and properties, and their application range can be expanded through enzymatic hydrolysis.

[0003] The enzymatic hydrolysis process usually includes three steps: crushing, enzymatic hydrolysis, and separation. The purpose of crushing is to crush some insoluble solid substrates into smaller particles or grind them to increase the contact area between the substrate and the enzyme and promote the enzymatic hydrolysis reaction. Separation is to separate the components in the mixed solution after the enzymatic hydrolysis reaction. The prior art often requires separate operations for the three steps of oligopeptide enzymatic hydrolysis reaction, which is complex in structure and cumbersome in operation, greatly reducing the efficiency of oligopeptide enzymatic hydrolysis reaction, and therefore needs to be improved. Utility Model Content

[0004] The utility model provides an oligopeptide enzymatic hydrolysis reaction device, which is only provided with one power device and can simultaneously complete the crushing, enzymatic hydrolysis and separation of the substrate by using the one power device, thereby solving the problems of complex structure and troublesome operation of the existing oligopeptide enzymatic hydrolysis reaction device.

[0005] In order to solve the above problems, the utility model proposes the following technical solutions: an oligopeptide enzymatic hydrolysis reaction device, comprising a support frame, on which a reaction box is fixedly arranged; a crushing box is fixedly arranged on the side wall of the reaction box, and the crushing box is connected to the reaction box through a connecting pipe; a motor is arranged on the side wall of the crushing box, a crushing shaft is fixedly connected to the output shaft of the motor, and the crushing shaft extends into the reaction box; an active bevel gear located in the reaction box is fixedly arranged on the crushing shaft; a stirring shaft is rotatably arranged in the reaction box, and a driven bevel gear meshing with the active bevel gear is fixedly connected to the stirring shaft; a centrifugal cylinder located below the reaction box is rotatably arranged in the support frame, and the centrifugal cylinder is fixedly connected to the stirring shaft.

[0006] As an improvement, a feed port is provided on the crushing box, a discharge pipe is provided at the bottom of the reaction box, and an electric control valve is provided on the discharge pipe.

[0007] As an improvement, the centrifugal cylinder is provided with an entry hole corresponding to the discharge pipe, and a screw plug is threadedly connected to the entry hole; a signal receiver is fixedly provided on the screw plug, and a signal transmitter corresponding to the signal receiver is provided on the discharge pipe.

[0008] As an improvement, a heating resistor is arranged in the reaction box, and a power supply device for providing power to the heating resistor is arranged on the outer wall of the reaction box; and an air inlet pipe is arranged and connected to the reaction box.

[0009] As an improvement, a control module is provided on the power supply device, and the control module is connected to the motor circuit; the control module is connected to the signal receiver circuit.

[0010] Beneficial effects of the utility model:

[0011] The crushing shaft 12 is fixedly provided with a driving bevel gear 13 located in the reaction box 2, and the stirring shaft 15 is fixedly connected with a driven bevel gear 14 meshing with the driving bevel gear 13; by setting the mutually meshing driving bevel gear 13 and the driven bevel gear 14, the rotation of the crushing shaft 12 can be transmitted to the stirring shaft 15 to speed up the efficiency of the enzymatic hydrolysis reaction, and there is no need to provide an additional power device to stir the enzymatic hydrolysis reaction. At the same time, a centrifugal cylinder 7 located below the reaction box 2 is rotatably provided in the support frame, and the centrifugal cylinder 7 is fixedly connected to the stirring shaft 15; by setting the centrifugal cylinder 7 fixedly connected to the stirring shaft 15, the rotation of the stirring shaft 15 can be used to provide centrifugal force to the centrifugal cylinder 7, so as to achieve the effect of separating the enzymatic hydrolysis reactants. Therefore, the utility model only provides one power device, which can provide crushing force, stirring force and centrifugal force required for separation for the enzymatic hydrolysis reaction at the same time, greatly simplifying the structure, increasing continuity, and improving the efficiency of the enzymatic hydrolysis reaction. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 It is a stereoscopic diagram of an oligopeptide enzymatic hydrolysis reaction device of the utility model.

[0013] Figure 2 This is a diagram showing the internal structure of a crushing box of an oligopeptide enzymatic hydrolysis reaction device of the utility model.

[0014] Figure 3 The utility model is a diagram showing the internal structure of a reaction box of an oligopeptide enzymatic hydrolysis reaction device.

[0015] Figure 4 The utility model is a cross-sectional view of an oligopeptide enzymatic hydrolysis reaction device.

[0016] 1. Support frame; 2. Reaction box; 3. Connecting pipe; 4. Crushing box; 5. Power supply device; 6. Control module; 7. Centrifugal cylinder; 8. Motor; 9. Feed inlet; 10. Discharge pipe; 11. Signal transmitter; 12. Crushing shaft; 13. Active bevel gear; 14. Driven bevel gear; 15. Stirring shaft; 16. Inlet pipe; 17. Screw plug; 18. Signal receiver; 19. Heating resistor; 20. Inlet hole; 21. Electric control valve. DETAILED DESCRIPTION

[0017] The utility model is further described below in conjunction with the accompanying drawings.

[0018] according to Figure 1-4 As shown: the utility model provides an oligopeptide enzymatic hydrolysis reaction device: it includes a support frame 1, on which a reaction box 2 is fixedly arranged; a crushing box 4 is fixedly arranged on the side wall of the reaction box 2, and the crushing box 4 is connected to the reaction box 2 through a connecting pipe 3; a motor 8 is arranged on the side wall of the crushing box 4, and a crushing shaft 12 is fixedly connected to the output shaft of the motor 8, and the crushing shaft 12 extends into the reaction box 2; an active bevel gear 13 located in the reaction box 2 is fixedly arranged on the crushing shaft 12; a stirring shaft 15 is rotatably arranged in the reaction box 2, and a driven bevel gear 14 meshing with the active bevel gear 13 is fixedly connected to the stirring shaft 15; a centrifugal drum 7 located below the reaction box 2 is rotatably arranged in the support frame 1, and the centrifugal drum 7 is fixedly connected to the stirring shaft 15.

[0019] Only one power device is provided, and the crushing, enzymolysis and separation of the substrate can be completed simultaneously by using the power device, which can solve the problems of complex structure and troublesome operation of the existing oligopeptide enzymolysis reaction device.

[0020] The crushing box 4 is provided with a feed port 9, the bottom of the reaction box 2 is provided with a discharge pipe 10, and the discharge pipe 10 is provided with an electric control valve 21. The centrifugal cylinder 7 is provided with an entry hole 20 corresponding to the discharge pipe 10, and a screw plug 17 is threadedly connected to the entry hole 20; a signal receiver 18 is fixedly provided on the screw plug 17, and a signal transmitter 11 corresponding to the signal receiver 18 is provided on the discharge pipe 10.

[0021] When the motor 8 is working, it will drive the centrifuge cylinder 7 to rotate, so that the positions of the discharge pipe 10 and the entrance hole 20 no longer correspond; and by setting the signal transmitter 11 and the signal receiver 18, they can be realigned before centrifuging the enzymatic hydrolysate, so that the discharge pipe 10 and the entrance hole 20 are aligned, so that the reacted solution in the reaction box 2 enters the centrifuge cylinder 7.

[0022] A heating resistor 19 is arranged in the reaction box 2 , and a power supply device 5 for providing power to the heating resistor 19 is arranged on the outer wall of the reaction box 2 ; an air inlet pipe 16 is arranged and connected to the reaction box 2 .

[0023] The heating resistor 19 can provide a suitable temperature for the enzymatic hydrolysis reaction, and the provision of the air inlet pipe 16 facilitates the addition of specific gas into the reaction box 2 to assist the reaction.

[0024] The power supply device 5 is provided with a control module 6 , and the control module 6 is connected to the motor 8 circuit; the control module 6 is connected to the signal receiver 18 circuit.

[0025] The control module 6 can receive the signal transmitted by the signal receiver 18 , and the control module 6 can control the motor 8 to work.

[0026] Principle of the utility model

[0027] When the utility model is used, the motor 8 is started, and the substrate is added into the crushing box 4 from the feed port 9. The motor 8 rotates at high speed to drive the crushing shaft 12 to crush the substrate in the crushing box 4, and the crushed substrate enters the reaction box 2 through the connecting pipe 3 for enzymolysis reaction. Due to the meshing action of the active bevel gear 13 and the driven bevel gear 14, the crushing shaft 12 drives the stirring shaft 15 to rotate when it rotates, so the stirring shaft 15 can stir the enzymolyzate and accelerate the reaction rate.

[0028] When the enzymatic hydrolysis reaction is finished, the speed of the control motor 8 is reduced to make the signal transmitter 11 and the signal receiver 18 work; when the stirring shaft 15 rotates, it can drive the centrifugal drum 7 to rotate; when the centrifugal drum 7 rotates to the point where the signal receiver 18 is directly below the signal transmitter 11, the signal receiver 18 immediately transmits a signal to the control module 6 upon receiving the signal, so that the control module 6 controls the motor 8 to stop working. At this time, the discharge pipe 10 is aligned with the entry hole 20, the screw plug 17 is taken out, and the electric control valve 21 is opened through the control module 6, so that the enzymatic solution and other substances in the reaction box 2 enter the centrifugal drum 7 through the discharge pipe 10; the screw plug 17 is inserted again, and the motor 8 is controlled to rotate at a high speed, thereby providing centrifugal force for the centrifugal drum 7 to separate the enzymatic product. In summary, the utility model only sets up one power device, and uses one power device to simultaneously complete the crushing, enzymatic hydrolysis and separation of the substrate, which can solve the problems of complex structure and cumbersome operation of the existing oligopeptide enzymatic hydrolysis reaction device.

[0029] The above description of the utility model and its implementation methods is not restrictive. The drawings show only one implementation method of the utility model, and the actual structure is not limited thereto. In short, if ordinary technicians in this field are inspired by it and design structural methods and embodiments similar to the technical solution without creativity without departing from the purpose of the invention of the utility model, they should all fall within the protection scope of the utility model.

Claims

1. An oligopeptide enzymatic hydrolysis reaction device, comprising a support frame (1), on which a reaction box (2) is fixedly arranged; characterized in that: A crushing box (4) is fixedly arranged on the side wall of the reaction box (2), and the crushing box (4) is connected to the reaction box (2) through a connecting pipe (3); a motor (8) is arranged on the side wall of the crushing box (4), and a crushing shaft (12) is fixedly connected to the output shaft of the motor (8), and the crushing shaft (12) extends into the reaction box (2); a driving bevel gear (13) located in the reaction box (2) is fixedly arranged on the crushing shaft (12); a stirring shaft (15) is rotatably arranged in the reaction box (2), and a driven bevel gear (14) meshing with the driving bevel gear (13) is fixedly connected to the stirring shaft (15); a centrifugal cylinder (7) located below the reaction box (2) is rotatably arranged in the support frame (1), and the centrifugal cylinder (7) is fixedly connected to the stirring shaft (15).

2. The oligopeptide enzymatic hydrolysis reaction device according to claim 1, characterized in that: The crushing box (4) is provided with a feed port (9), the bottom of the reaction box (2) is provided with a discharge pipe (10), and the discharge pipe (10) is provided with an electric control valve (21).

3. An oligopeptide enzymatic hydrolysis reaction device according to claim 2, characterized in that: The centrifugal cylinder (7) is provided with an entry hole (20) corresponding to the discharge pipe (10), and a screw plug (17) is threadedly connected to the entry hole (20); a signal receiver (18) is fixedly provided on the screw plug (17), and a signal transmitter (11) corresponding to the signal receiver (18) is provided on the discharge pipe (10).

4. The oligopeptide enzymatic hydrolysis reaction device according to claim 3, characterized in that: A heating resistor (19) is arranged inside the reaction box (2), and a power supply device (5) for providing power to the heating resistor (19) is arranged on the outer wall of the reaction box (2); an air intake pipe (16) is arranged and connected to the reaction box (2).

5. An oligopeptide enzymatic hydrolysis reaction device according to claim 4, characterized in that: The power supply device (5) is provided with a control module (6), and the control module (6) is connected to the motor (8) circuit; the control module (6) is connected to the signal receiver (18) circuit.