Automatic dialysis circulating device

Abstract

The utility model discloses an automatic dialysis circulating device which comprises a container, a reverse osmosis device, a liquid pump and a temperature control device, the container, the reverse osmosis device, the liquid pump and the temperature control device are communicated to form a circulating pipeline, the container is connected with the reverse osmosis device through a liquid outlet pipe, the reverse osmosis device is connected with the liquid pump through a first connecting pipe, and the liquid pump is connected with the temperature control device through a second connecting pipe. The temperature control device is connected with the container through the liquid inlet pipe, at least one pair of clamping plates which are oppositely arranged is installed in the container, the dialysis bag can be clamped between the pair of clamping plates, and the dialysis bag is kept in a horizontal state. According to the device, reverse dialysis is adopted through the circulating pipeline, the use amount of dialysate is reduced, deionized water can be recycled, and waste is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of silk fibroin dialysis devices, and more specifically to an automatic dialysis circulation device. Background Art

[0002] Silk fibroin is usually not easily soluble in water due to the characteristics of its molecular structure. In order to dissolve it, a specific salt solution system is usually required. However, these added small molecule salts may have an adverse effect on the application of silk fibroin solution, so they must be removed by dialysis. Traditional dialysis methods usually put the silk fibroin solution into a dialysis bag and soak it in deionized water, and reduce the concentration of small molecules in the solution by frequently changing the deionized water. This approach not only consumes a large amount of deionized water, but also requires a lot of human resources. In addition, silk fibroin can only remain stable under low temperature conditions to prevent denaturation due to high temperature. Therefore, it is common practice to perform dialysis in a refrigerator, but this limits the possibility of using stirring to accelerate the flow of dialysate, so a technical solution is needed to solve the above problems. Utility Model Content

[0003] The purpose of the utility model is to overcome the above-mentioned shortcomings of the prior art, enable deionized water to be circulated and utilized to reduce the amount of deionized water used, and provide an automatic dialysis circulation device.

[0004] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0005] The utility model discloses an automatic dialysis circulation device, comprising a container, a reverse osmosis device, a liquid pump, and a temperature control device. The container, the reverse osmosis device, the liquid pump, and the temperature control device are connected to form a circulation pipeline. The container is connected to the reverse osmosis device through a liquid outlet pipe, the reverse osmosis device is connected to the liquid pump through a first connecting pipe, the liquid pump is connected to the temperature control device through a second connecting pipe, the temperature control device is connected to the container through a liquid inlet pipe, at least a pair of clamps arranged opposite to each other are installed inside the container, a dialysis bag can be clamped between the pair of clamps, and the dialysis bag is kept in a horizontal state.

[0006] Furthermore, the container includes a shell and a top cover, the upper end of the shell is open, the top cover is installed at the upper end opening of the shell, the lower end surface of the shell is provided with a liquid outlet, the liquid outlet is connected to the liquid outlet pipe, and the upper end of the side wall of the shell is provided with a first liquid inlet, which is connected to the liquid inlet pipe.

[0007] Furthermore, a second liquid inlet is provided at an upper end of the side wall of the shell.

[0008] Furthermore, a plurality of pairs of the clamping plates are arranged in the container, the plurality of pairs of the clamping plates are arranged equidistantly along the height direction of the container, and two adjacent pairs of the clamping plates are arranged vertically and staggered in the horizontal direction.

[0009] Furthermore, a baffle is provided on the side wall of the shell, and the baffle can support the clamping plate.

[0010] Furthermore, the baffle is provided with a clamping plate, the clamping plate extends upward, a buckle is provided at the upper end of the clamping plate, a step is provided at the upper end surface of the clamping plate, and the buckle is buckled with the step.

[0011] Furthermore, the clamping plate is provided with a clamping groove, the clamping groove is connected to the upper end surface of the clamping plate, and bag clamps are provided at both ends of the dialysis bag, and the bag clamps can be inserted into the clamping groove.

[0012] Furthermore, the clamping plate is provided with a through groove, and the through groove communicates with the clamping groove and the side wall of the clamping plate.

[0013] Furthermore, the clamp includes a fixed platform and a rotating rod, wherein the fixed platform is located on the upper end surface of the clamp, the fixed platform is provided with a rotating groove, the rotating rod is rotatably installed in the rotating groove, and the rotating rod rotates to form a limit on the upper side of the bag clamp.

[0014] Furthermore, the upper end surface of the clamping plate is provided with a concave hole, and the rotating rod is provided with a convex block corresponding to the concave hole, and the convex block can be inserted into the concave hole.

[0015] The beneficial effects of the utility model are:

[0016] 1. The utility model reduces the amount of dialysate through a circulating pipeline, so that the dialysate can be recycled. The dialysis bag in the container is immersed in deionized water, and the deionized water is drawn from the bottom of the container and passes through a reverse osmosis device and a temperature control device. The reverse osmosis device removes salt and other small molecular impurities therein, and the temperature control device keeps the temperature of the deionized water at a low temperature, so that the deionized water can be recycled, thereby ensuring the quality stability of the dialysate during the dialysis process.

[0017] 2. The staggered adjacent clamps in the utility model enable the upper and lower adjacent layers of dialysis bags to be vertically arranged, and the ionic liquid in the container will form a flow obstruction when flowing through the dialysis bag, so that the flowing deionized water can better pass through the dialysis bag to dialyze the silk fibroin in the dialysis bag, thereby improving the dialysis efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 is a schematic diagram of this embodiment.

[0019] Figure 2 It is a partial cross-sectional view of the container in this embodiment.

[0020] Figure 3 for Figure 2 Enlarged view of point A in the middle.

[0021] Figure 4 Schematic diagram of the structure of the splint and the dialysis bag in this embodiment.

[0022] Figure numerals: 1. container; 11. shell; 111. baffle; 112. clamping plate; 113. buckle; 12. liquid outlet; 13. first liquid inlet; 14. second liquid inlet; 15. liquid outlet pipe; 16. liquid inlet pipe; 17. top cover; 2. reverse osmosis device; 21. first connecting pipe; 3. liquid pump; 31. second connecting pipe; 4. temperature control device; 5. clamping plate; 51. clamping groove; 511. through groove; 52. fixing table; 521. rotating groove; 53. rotating rod; 54. recessed hole; 55. step; 6. dialysis bag; 61. bag clamp. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in this embodiment to clearly and completely describe the technical solution in this embodiment. Obviously, the described embodiment is only a part of the embodiment of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0024] like Figure 1 , Figure 2 As shown, this embodiment discloses an automatic dialysis circulation device, including a container 1, a reverse osmosis device 2, a liquid pump 3, and a temperature control device 4. The container 1 includes a shell 11 and a top cover 17. The upper end of the shell 11 is open, and the dialysis bag 6 can be placed in the shell 11 from the upper end opening of the shell 11. The top cover 17 is installed at the upper end opening of the shell 11. The top cover 17 can cover the upper end opening of the shell 11 to play a dust-proof role. The lower end surface of the shell 11 is provided with a liquid outlet 12, and the liquid outlet 12 is connected to a liquid outlet pipe 15. The container 1 is connected to the reverse osmosis device 2 through the liquid outlet pipe 15. The upper end of the side wall of the shell 11 is provided with a liquid outlet 12. A first liquid inlet 13 is provided, the first liquid inlet 13 is connected to a liquid inlet pipe 16, the reverse osmosis device 2 is connected to a liquid pump 3 through a first connecting pipe 21, the liquid pump 3 is connected to a temperature control device 4 through a second connecting pipe 31, the temperature control device 4 is connected to a container 1 through the liquid inlet pipe 16, the container 1, the reverse osmosis device 2, the liquid pump 3, and the temperature control device 4 are connected to form a circulation pipeline, the container 1 is used to place a dialysis bag 6 of silk fibroin that needs to be dialyzed, the dialysis bag 6 is completely immersed in the solution of the container 1, and the deionized water in the entire circulation pipeline is driven by the liquid pump 3 to flow, so that the solution in the container 1 flows from top to bottom;

[0025] The reverse osmosis device 2 is responsible for purifying the dialysate. It effectively removes salt and other small molecular impurities from the dialysate produced during the continuous circulation dialysis process, thereby regenerating pure dialysate for use in subsequent dialysis steps, thereby improving the dialysis efficiency and ensuring the quality stability of the dialysate during the dialysis process.

[0026] The temperature control device 4 is located in front of the first liquid inlet 13 to ensure that the temperature of the deionized water entering the container 1 meets the requirements. The temperature control device 4 has the function of accurately adjusting the solution temperature to ensure that the dialysate reaches a preset temperature during the circulation process. The temperature control mechanism effectively prevents the denaturation and precipitation of silk fibroin due to the increase in temperature during the dialysis process, thereby maintaining the quality and stability of the silk fibroin solution.

[0027] like Figure 2 As shown, a second liquid inlet 14 is provided at the upper end of the side wall of the shell 11. The second liquid inlet 14 has the same height as the first liquid inlet 13. A liquid level sensing device is installed below the second liquid inlet 14. When the liquid level is too low, deionized water can be added to the container 1 through the second liquid inlet 14.

[0028] like Figure 2 , Figure 3 , Figure 4 As shown, a plurality of pairs of splints 5 are provided in the container 1, and the plurality of pairs of splints 5 are equidistantly arranged along the height direction of the container 1, and two adjacent pairs of splints 5 are vertically staggered in the horizontal direction. The staggered adjacent splints 5 enable the dialysis bags 6 of the upper and lower adjacent layers to be vertically arranged, and a flow obstruction is formed when the deionized water in the container 1 flows through the dialysis bag 6, so that the flowing deionized water can better dialyze the silk fibroin in the dialysis bag 6 through the dialysis bag 6, thereby improving the dialysis efficiency.

[0029] The side wall of the shell 11 is provided with a baffle 111, which can support the lower end surface of the clamp 5. The baffle 111 is provided with a clamping plate 112, which extends upward. The upper end of the clamping plate 112 is provided with a buckle 113, and the upper end surface of the clamp 5 is provided with a step 55. The buckle 113 is engaged with the step 55. The clamp 5 is installed into the shell 11 from the upper end opening of the shell 11. The clamp 5 is placed on the upper end surface of the baffle 111 and is fixed by the buckle 113 of the clamp 112 which can be elastically deformed.

[0030] The splints 5 are respectively installed on two opposite side walls of the shell 11. The dialysis bag 6 can be clamped between the two splints 5, and the dialysis bag 6 remains in a horizontal state. The horizontally arranged dialysis bag 6 can be perpendicular to the flow direction of the deionized water in the container 1, which can improve the dialysis efficiency of silk fibroin.

[0031] like Figure 4As shown, the splint 5 is provided with a clamping groove 51, which is connected to the upper end surface of the splint 5, and bag clamps 61 are provided at both ends of the dialysis bag 6, which can be inserted into the clamping groove 51. The splint 5 is provided with a through groove 511, which is connected to the clamping groove 51 and the side wall of the splint 5, and the through groove 511 is used to accommodate the part of the dialysis bag 6 connected to the bag clamp 61. The outer edge of the through groove 511 and the upper edge of the part of the clamping groove 51 connected to the through groove 511 are rounded to prevent damage to the dialysis bag 6.

[0032] The splint 5 includes a fixed platform 52 and a rotating rod 53. The fixed platform 52 is located on the upper end surface of the splint 5. The fixed platform 52 is provided with a rotating groove 521. The rotating rod 53 is rotatably installed in the rotating groove 521. The rotating rod 53 rotates to form a limit on the upper side of the bag clamp 61. When the bag clamp 61 is inserted into the clamping groove 51, the rotating rod 53 is rotated to rotate the rotating rod 53 to the upper side of the clamping groove 51 and the bag clamp 61. The upper end surface of the splint 5 is provided with a concave hole 54, and the rotating rod 53 can be inserted into the concave hole 54. The lower end surface of the rotating rod 53 is provided with a protrusion corresponding to the concave hole 54, and the protrusion can be inserted into the concave hole 54. The rotating rod 53 has the ability of elastic deformation. When the protrusion is against the upper end surface of the splint 5, the rotating rod 53 can still rotate.

[0033] The above is only a preferred embodiment of the present invention. The protection scope of the present invention is not limited to the above embodiments. All technical solutions under the concept of the present invention belong to the protection scope of the present invention. It should be pointed out that for ordinary technicians in this technical field, some improvements and modifications without departing from the principle of the present invention should also be regarded as the protection scope of the present invention.

Claims

1. An automatic dialysis circulation device, characterized in that: The invention comprises a container (1), a reverse osmosis device (2), a liquid pump (3), and a temperature control device (4); the container (1), the reverse osmosis device (2), the liquid pump (3), and the temperature control device (4) are connected to form a circulation pipeline; the container (1) is connected to the reverse osmosis device (2) via a liquid outlet pipe (15); the reverse osmosis device (2) is connected to the liquid pump (3) via a first connecting pipe (21); the liquid pump (3) is connected to the temperature control device (4) via a second connecting pipe (31); the temperature control device (4) is connected to the container (1) via a liquid inlet pipe (16); at least one pair of clamping plates (5) arranged opposite to each other are installed inside the container (1); a dialysis bag (6) can be clamped between the pair of clamping plates (5); and the dialysis bag (6) is kept in a horizontal state.

2. An automatic dialysis circulation device according to claim 1, characterized in that: The container (1) comprises a shell (11) and a top cover (17); the upper end of the shell (11) is open; the top cover (17) is mounted on the upper end opening of the shell (11); a liquid outlet (12) is provided on the lower end surface of the shell (11); the liquid outlet (12) is connected to the liquid outlet pipe (15); a first liquid inlet (13) is provided on the upper end of the side wall of the shell (11); the first liquid inlet (13) is connected to the liquid inlet pipe (16).

3. An automatic dialysis circulation device according to claim 2, characterized in that: A second liquid inlet (14) is provided at the upper end of the side wall of the housing (11).

4. The automatic dialysis circulation device according to claim 1, characterized in that: A plurality of pairs of the clamping plates (5) are arranged in the container (1), the plurality of pairs of the clamping plates (5) are arranged equidistantly along the height direction of the container (1), and two adjacent pairs of the clamping plates (5) are arranged vertically and staggered in the horizontal direction.

5. The automatic dialysis circulation device according to claim 2, characterized in that: A baffle (111) is provided on the side wall of the housing (11), and the baffle (111) is capable of supporting the clamping plate (5).

6. An automatic dialysis circulation device according to claim 5, characterized in that: The baffle (111) is provided with a clamping plate (112), the clamping plate (112) extends upward, a buckle (113) is provided at the upper end of the clamping plate (112), a step (55) is provided at the upper end surface of the clamping plate (5), and the buckle (113) is buckled with the step (55).

7. An automatic dialysis circulation device according to claim 1, characterized in that: The clamping plate (5) is provided with a clamping groove (51), and the clamping groove (51) is connected to the upper end surface of the clamping plate (5). Both ends of the dialysis bag (6) are provided with bag clamps (61), and the bag clamps (61) can be inserted into the clamping groove (51).

8. An automatic dialysis cycle device according to claim 7, characterized in that: The clamping plate (5) is provided with a through groove (511), and the through groove (511) communicates with the clamping groove (51) and the side wall of the clamping plate (5).

9. An automatic dialysis cycle device according to claim 7, characterized in that: The clamping plate (5) comprises a fixed platform (52) and a rotating rod (53). The fixed platform (52) is located on the upper end surface of the clamping plate (5). The fixed platform (52) is provided with a rotating groove (521). The rotating rod (53) is rotatably installed in the rotating groove (521). The rotating rod (53) rotates to form a limit on the upper side of the bag clamp (61).

10. An automatic dialysis cycle device according to claim 9, characterized in that: The upper end surface of the clamping plate (5) is provided with a concave hole (54), and the rotating rod (53) is provided with a convex block corresponding to the concave hole (54), and the convex block can be inserted into the concave hole (54).

Images